Aim: To identify the health gains related to nursing interventions in the telephone follow -up of adult patients with cardiac pathology. Methodology: Systematic literature review by research in EBSCO, (CINAHL and MEDLINE) in the publication time interval between January 2012 and October 2017, using the PICO method. Elected 8 articles for analysis. Results: Health Gains were identified related to: symptomatic control, management of the therapeutic regimen, use of health services, safety/adverse events and quality of life. Conclusions: The telephone follow -up contributes to optimize the follow -up to the patient, translating into health gains sensitive to nursing care. Implication to professional practice: In the contexts of nursing practice for adult patients with cardiac pathology, telephone follow -up proves to be an intervention to be taken into account, translating into gains in health, promoting patient follow -up, improving training in disease management. Key words: Tele-nursing; counseling; nursing; cardiac patient