6 results on '"Poo Lee Ong"'
Search Results
2. The Safety of Treatment with Cefepime in Elderly Patients
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Joyce Mallari Cabradilla, Yew Yoong Ding, Eloisa Marasigan, Huei Nuo. Tan, Nathalie Declarador, Poo Lee Ong, Keng Teng Tan, and Ela Villaverde
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medicine.medical_specialty ,business.industry ,Cefepime ,Internal medicine ,Medicine ,Geriatrics and Gerontology ,business ,medicine.drug - Published
- 2019
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3. Acute Functional Outcomes in Critically Ill COVID-19 Patients
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Ser Hon Puah, Poo Lee Ong, Matthew Rong Jie Tay, and Shuen Loong Tham
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medicine.medical_specialty ,Multivariate analysis ,Coronavirus disease 2019 (COVID-19) ,intensive care units ,medicine.medical_treatment ,coronavirus ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,medicine ,Dependent Ambulation ,critical illness ,030212 general & internal medicine ,muscle weakness ,lcsh:R5-920 ,Rehabilitation ,Critically ill ,business.industry ,SARS-CoV-2 ,General Medicine ,Odds ratio ,Brief Research Report ,acute respiratory distress syndrome ,dyspnea ,Intensive care unit ,030228 respiratory system ,Emergency medicine ,dependent ambulation ,Medicine ,business ,lcsh:Medicine (General) ,Cohort study - Abstract
Background:COVID-19 (Coronavirus Disease 2019) is a global cause of morbidity and mortality currently. We aim to describe the acute functional outcomes of critically ill coronavirus disease 2019 (COVID-19) patients after transferring out of the intensive care unit (ICU).Methods:51 consecutive critically ill COVID-19 patients at a national designated center for COVID-19 were included in this exploratory, retrospective observational cohort study from January 1 to May 31, 2020. Demographic and clinical data were collected and analyzed. Functional outcomes were measured primarily with the Functional Ambulation Category (FAC), and divided into 2 categories: dependent ambulators (FAC 0–3) and independent ambulators (FAC 4–5). Multivariate analysis was performed to determine associations.Results:Many patients were dependent ambulators (47.1%) upon transferring out of ICU, although 92.2% regained independent ambulation at discharge. On multivariate analysis, we found that a Charlson Comorbidity Index of 1 or more (odds ratio 14.02, 95% CI 1.15–171.28,P= 0.039) and a longer length of ICU stay (odds ratio 1.50, 95% CI 1.04–2.16,P= 0.029) were associated with dependent ambulation upon discharge from ICU.Conclusions:Critically ill COVID-19 survivors have a high level of impairment following discharge from ICU. Such patients should be screened for impairment and managed appropriately by rehabilitation professionals, so as to achieve good functional outcomes on discharge.
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- 2020
4. Immediate Functional Outcomes of Survivors with Critically-ill COVID-19
- Author
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Matthew Rong Jie Tay, Poo Lee Ong, Ser Hon Puah, and Shuen-Loong Tham
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medicine.medical_specialty ,Muscle Weakness ,Rehabilitation ,Multivariate analysis ,SARS-CoV-2 ,Dependent Ambulation Intensive Care Units ,business.industry ,Critically ill ,medicine.medical_treatment ,Psychological intervention ,Physical Therapy, Sports Therapy and Rehabilitation ,Odds ratio ,Intensive care unit ,law.invention ,law ,Emergency medicine ,medicine ,Dependent Ambulation ,business ,Acute Respiratory Distress Syndrome ,Research Poster 1709874 ,Cohort study - Abstract
Research Objectives To describe the functional outcomes of patients with critically ill coronavirus disease 2019 (COVID-19) after transfer out of intensive care unit (ICU). Design Retrospective observational cohort study. Setting National designated center for patients with COVID-19. Participants 51 consecutive critically ill COVID-19 patients admitted to the ICU. Interventions Patients were referred for physical therapy after transferring out from ICU if they had functional impairments. Main Outcome Measures Functional outcomes were measured primarily with the Functional Ambulation Category (FAC), and divided into 2 categories: dependent ambulators (FAC 0-3) and independent ambulators (FAC 4-5). Secondary outcomes measured included ADL dependence of patients and the need for supplemental oxygen. Results All patients were premorbidly independent in walking and in basic ADLs, and did not require supplementary oxygen. Upon transfer out of ICU, there were 24 patients (47.1%) who were dependent walkers (defined as FAC of 0-3) with 22 patients (43.1%) who were dependent in 1 or more basic ADLs. However, upon discharge, a majority achieved independence in ambulation and basic ADLs (92.2% and 90.2% respectively). All 41 patients (80.4%) who required continuous supplementary oxygen upon transferring out of ICU did not require supplementary oxygen on discharge. On multivariate analysis, we found that a Charlson Comorbidity Index of 1 or more (odds ratio 14.02, 95% CI 1.15-171.28, P=0.039) and a longer length of ICU stay (odds ratio 1.50, 95% CI 1.04-2.16, P=0.029) were associated with dependent ambulation upon discharge from ICU. Conclusions Critically ill COVID-19 survivors have a high level of impairment following discharge from ICU. Such patients should be screened for impairment and managed appropriately by rehabilitation professionals, so as to achieve good functional outcomes on discharge. Author(s) Disclosures None to disclose.
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- 2021
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5. The Validity of the Montreal Cognitive Assessment for Moderate to Severe Traumatic Brain Injury Patients: A Pilot Study
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Poo Lee Ong, Tegan Kate Plunkett, Matthew Rong Jie Tay, Keng He Kong, Wanping Huang, and Yan Ming Soh
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Adult ,Male ,030506 rehabilitation ,medicine.medical_specialty ,Repeatable Battery for the Assessment of Neuropsychological Status ,Traumatic brain injury ,Cross-sectional study ,medicine.medical_treatment ,Physical Therapy, Sports Therapy and Rehabilitation ,Pilot Projects ,Neuropsychological Tests ,Sensitivity and Specificity ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,Brain Injuries, Traumatic ,medicine ,Humans ,Cognitive Dysfunction ,Neuropsychological assessment ,Aged ,Rehabilitation ,medicine.diagnostic_test ,business.industry ,Montreal Cognitive Assessment ,Reproducibility of Results ,Middle Aged ,medicine.disease ,Mental Status and Dementia Tests ,Cross-Sectional Studies ,ROC Curve ,Predictive value of tests ,Physical therapy ,Observational study ,Female ,0305 other medical science ,business ,030217 neurology & neurosurgery - Abstract
Objective The aim of the study was to pilot the use of Montreal Cognitive Assessment as a quick clinical screen for cognitive assessment in traumatic brain injury patients. Design The study recruited 61 participants with moderate to severe traumatic brain injury presenting to a tertiary rehabilitation center under the Brain Injury Program. A Montreal Cognitive Assessment questionnaire and neuropsychological battery (Repeatable Battery for the Assessment of Neuropsychological Status and Color Trails Test) were administered to participants who had completed inpatient rehabilitation. Results Receiver operating characteristic analysis for the Montreal Cognitive Assessment revealed an optimal balance of sensitivity and specificity at 24/25 to discriminate participants who were classified as less than 5th centile on the Total Scale Index on the Repeatable Battery for the Assessment of Neuropsychological Status. This achieved a sensitivity, specificity, PPV, and NPV of 73.9%, 86.5%, 77.3%, and 84.2%, respectively. Receiver operating characteristic analysis for the trail making subtest of the Montreal Cognitive Assessment achieved a sensitivity, specificity, PPV, and NPV of 79.4%, 74.1%, 79.4%, and 74.1% in identifying patients classified as less than 5th centile on Color Trail Test part 2. Conclusions The use of Montreal Cognitive Assessment displayed good validity in identifying patients with clinically significant impairment on a standard neuropsychological assessment battery in the study population. However, it may lack sensitivity for estimating mild levels of impairment.
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- 2019
6. Rehabilitation of patients with platypnea-orthodeoxia syndrome in COVID-19 pneumonia: Two case reports
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Audrey Jia Yi Lee, Matthew Rong Jie Tay, Shuen-Loong Tham, and Poo Lee Ong
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Mechanical ventilation ,Pediatrics ,medicine.medical_specialty ,Rehabilitation ,business.industry ,medicine.medical_treatment ,COVID-19 ,acute respiratory distress syndrome ,medicine.disease ,Intensive care unit ,rehabilitation ,law.invention ,Pneumonia ,platypnea-orthodeoxia syndrome ,law ,Oxygen therapy ,Intensive care ,medicine ,case report ,pneumonia ,Respiratory system ,Complication ,business - Abstract
Platypnea-orthodeoxia syndrome, characterized by dyspnoea and arterial desaturation while upright, is a rare complication of acute respiratory distress syndrome. We report here 2 patients with COVID-19 pneumonia, who were diagnosed with platypnea-orthodeoxia syndrome during commencement of rehabilitation, 18 and 9 days respectively after admission to the intensive care unit. Both patients presented with normocapnic hypoxaemia. One patient required mechanical ventilation with supplemental oxygen during intensive care, while the other required high-flow nasal oxygen therapy. The manifestations of platypnea-orthodeoxia syndrome were most prominent during physiotherapy, when verticalization was attempted, and hindered further mobilization out of bed, including ambulation. This report describes the clinical manifestations of platypnea-orthodeoxia syndrome and the rehabilitative strategies carried out for these 2 patients. The platypnea-orthodeoxia syndrome in these patients resolved after 65 and 22 days respectively from the day of detection. This report highlights this potentially under-recognized phenomenon, which may be unmasked during rehabilitation of patients with COVID-19 pneumonia. Good functional outcomes were achieved with a combination of verticalization training with supplemental oxygen support, respiratory techniques training and progressive endurance and resistance training, whilst awaiting resolution of the platypneaorthodeoxia syndrome. LAY ABSTRACT Platypnea-orthodeoxia syndrome can be a rare complication in severe pneumonia. Patients with platypnea-orthodeoxia syndrome experience decreasing oxygen levels when assuming upright positions. This can interfere with walking and other activities that require an upright posture. We report here 2 patients with platypnea-orthodeoxia syndrome in severe COVID-19 pneumonia and describe their journey to recovery whilst undergoing rehabilitation and physical therapy. The various strategies that were helpful included the use of additional oxygen, special breathing techniques, as well as reducing the pace of the exercises delivered. By the end of their rehabilitation programmes, the 2 patients were able to walk without the need for additional oxygen. The platypnea-orthodeoxia syndrome resolved after 22 and 65 days from the day of detection.
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- 2020
- Full Text
- View/download PDF
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