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1. QSM reconstruction challenge 2.0: A realistic in silico head phantom for MRI data simulation and evaluation of susceptibility mapping procedures

Author

Renaud Hedouin, Jakob Meineke, Carlos Milovic, Berkin Bilgic, Christian Langkammer, Kwok-Shing Chan, José P. Marques, Ferdinand Schweser, Wietske van der Zwaag, Donders Institute for Brain, Cognition and Behaviour, Radboud University [Nijmegen], Philips Research [Germany], Philips Research, Department of Medical Physics and Biomedical Engineering (UCL), University College of London [London] (UCL), Pontificia Universidad Católica de Chile (UC), Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School [Boston] (HMS)-Massachusetts General Hospital [Boston], Harvard Medical School [Boston] (HMS), Harvard-MIT Division of Health Sciences and Technology [Cambridge], Massachusetts Institute of Technology (MIT), Neuroimagerie: méthodes et applications (Empenn), Institut National de la Santé et de la Recherche Médicale (INSERM)-Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE (IRISA-D5), Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Spinoza Center for Neuroimaging [Amsterdam], Medical University of Graz, State University of New York [Buffalo], Radboud university [Nijmegen], Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile., Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile., Massachusetts General Hospital [Boston]-Harvard Medical School [Boston] (HMS), Empenn, Université de Bretagne Sud (UBS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National de Recherche en Informatique et en Automatique (Inria)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-CentraleSupélec-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Bretagne Sud (UBS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), spinoza centre for neuroimaging, Center for biomedical imaging [Bufalo], University at Buffalo [SUNY] (SUNY Buffalo), State University of New York (SUNY)-State University of New York (SUNY), center for biomedical imaging [Buffalo], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes 1 (UR1), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), and Spinoza Centre for Neuroimaging

Subjects
Source code, Computer science, Property (programming), media_common.quotation_subject, computer.software_genre, Imaging phantom, 030218 nuclear medicine & medical imaging, law.invention, Full Papers—Computer Processing and Modeling, 03 medical and health sciences, 0302 clinical medicine, law, Voxel, [INFO.INFO-IM]Computer Science [cs]/Medical Imaging, Image Processing, Computer-Assisted, Humans, Radiology, Nuclear Medicine and imaging, Cartesian coordinate system, Computer vision, Computer Simulation, media_common, Ground truth, in silico head phantom, quantitative susceptibility mapping, Full Paper, business.industry, Phantoms, Imaging, [SCCO.NEUR]Cognitive science/Neuroscience, Relaxation (iterative method), Brain, Quantitative susceptibility mapping, MRI simulations, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Magnetic Resonance Imaging, Artificial intelligence, business, computer, Head, 030217 neurology & neurosurgery, Algorithms
Abstract

Purpose To create a realistic in silico head phantom for the second QSM reconstruction challenge and for future evaluations of processing algorithms for QSM. Methods We created a digital whole-head tissue property phantom by segmenting and postprocessing high-resolution (0.64 mm isotropic), multiparametric MRI data acquired at 7 T from a healthy volunteer. We simulated the steady-state magnetization at 7 T using a Bloch simulator and mimicked a Cartesian sampling scheme through Fourier-based processing. Computer code for generating the phantom and performing the MR simulation was designed to facilitate flexible modifications of the phantom in the future, such as the inclusion of pathologies as well as the simulation of a wide range of acquisition protocols. Specifically, the following parameters and effects were implemented: TR and TE, voxel size, background fields, and RF phase biases. Diffusion-weighted imaging phantom data are provided, allowing future investigations of tissue-microstructure effects in phase and QSM algorithms. Results The brain part of the phantom featured realistic morphology with spatial variations in relaxation and susceptibility values similar to the in vivo setting. We demonstrated some of the phantom's properties, including the possibility of generating phase data with nonlinear evolution over TE due to partial-volume effects or complex distributions of frequency shifts within the voxel. Conclusion The presented phantom and computer programs are publicly available and may serve as a ground truth in future assessments of the faithfulness of quantitative susceptibility reconstruction algorithms.

Published
2021

2. Cardiac displacement tracking with data assimilation combining a biomechanical model and an automatic contour detection

Author

Gautier Bureau, Dominique Chapelle, Jürgen Weese, Jaroslav Tintera, Radomir Chabiniok, Alexandra Groth, Philippe Moireau, Mathematical and Mechanical Modeling with Data Interaction in Simulations for Medicine (M3DISIM), Laboratoire de mécanique des solides (LMS), École polytechnique (X)-MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Inria Saclay - Ile de France, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), King‘s College London, Philips Research [Germany], Philips Research, Institute for Clinical and Experimental Medicine (IKEM), Zemzemi, Nejib, Ozenne, Valéry, Vigmond, Edward, Coudière, Yves, École polytechnique (X)-Mines Paris - PSL (École nationale supérieure des mines de Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Mines Paris - PSL (École nationale supérieure des mines de Paris)

Subjects
Computational model, Computer science, business.industry, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, 0206 medical engineering, 02 engineering and technology, Tracking (particle physics), 020601 biomedical engineering, Biophysical heart modeling, cine MRI, Displacement (vector), Bottleneck, 030218 nuclear medicine & medical imaging, Term (time), Cine mri, 03 medical and health sciences, 0302 clinical medicine, Data assimilation, Computer vision, Artificial intelligence, business, [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials, Cardiac imaging
Abstract

International audience; Data assimilation in computational models represents an essential step in building patient-specific simulations. This work aims at circumventing one major bottleneck in the practical use of data assimilation strategies in cardiac applications, namely, the difficulty of formulating and effectively computing adequate data-fitting term for cardiac imaging such as cine MRI. We here provide a proof-of-concept study of data assimilation based on automatic contour detection. The tissue motion simulated by the data assimilation framework is then assessed with displacements extracted from tagged MRI in six subjects, and the results illustrate the performance of the proposed method, including for circumferential displacements, which are not well extracted from cine MRI alone.

Published
2019

3. Spectral Photon-counting CT: Initial Experience with Dual-Contrast Agent K-Edge Colonography

Author

Heiner Daerr, Ernst J. Rummeny, Bernhard Brendel, Loic Boussel, Philippe Douek, Peter B. Noël, Daniela Muenzel, Ira Blevis, Ewald Roessl, Julia Herzen, Franz Pfeiffer, Daniel Bar-Ness, Philippe Coulon, Felix K. Kopp, Roland Proksa, Stefan Ruschke, Matthias Bartels, Alexander A. Fingerle, Axel Thran, Michal Rokni, Philips Healthcare, Philips Research [Germany], Philips Research, Imagerie et modélisation Vasculaires, Thoraciques et Cérébrales (MOTIVATE), Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physics Department, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Department of Radiology, Cardiological Hospital, Hospices Civils de Lyon, Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), and Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Gadolinium, media_common.quotation_subject, Iodine Compounds, chemistry.chemical_element, Lumen (anatomy), Contrast Media, Iodine, Imaging phantom, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Medicine, Contrast (vision), Radiology, Nuclear Medicine and imaging, media_common, Photons, business.industry, Phantoms, Imaging, Photon counting, digestive system diseases, chemistry, K-edge, 030220 oncology & carcinogenesis, business, Nuclear medicine, Material decomposition, Colonography, Computed Tomographic
Abstract

[DOI:\hrefhttps://dx.doi.org/10.1148/radiol.201616089010.1148/radiol.2016160890] [PubMed:\hrefhttps://www.ncbi.nlm.nih.gov/pubmed/2791870927918709]; International audience; Purpose To investigate the feasibility of using spectral photon-counting computed tomography (CT) to differentiate between gadolinium-based and nonionic iodine-based contrast material in a colon phantom by using the characteristic k edge of gadolinium. Materials and Methods A custom-made colon phantom was filled with nonionic iodine-based contrast material, and a gadolinium-filled capsule representing a contrast material-enhanced polyp was positioned on the colon wall. The colon phantom was scanned with a preclinical spectral photon-counting CT system to obtain spectral and conventional data. By fully using the multibin spectral information, material decomposition was performed to generate iodine and gadolinium maps. Quantitative measurements were performed within the lumen and polyp to quantitatively determine the absolute content of iodine and gadolinium. Results In a conventional CT section, absorption values of both contrast agents were similar at approximately 110 HU. Contrast material maps clearly differentiated the distributions, with gadolinium solely in the polyp and iodine in the lumen of the colon. Quantitative measurements of contrast material concentrations in the colon and polyp matched well with those of actual prepared mixtures. Conclusion Dual-contrast spectral photon-counting CT colonography with iodine-filled lumen and gadolinium-tagged polyps may enable ready differentiation between polyps and tagged fecal material. © RSNA, 2016.

Published
2016

4. Photon counting spectral CT component analysis of coronary artery atherosclerotic plaque samples

Author

Gerhard Martens, Axel Thran, Monica Sigovan, Loic Boussel, Ewald Roessl, Philippe Douek, Philippe Coulon, Service de Radiologie [Hôpital de la Croix-Rousse - HCL], Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon ( HCL ) -Hospices Civils de Lyon ( HCL ), 1 - Imagerie et modélisation Vasculaires, Thoraciques et Cérébrales ( MOTIVATE ), Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé ( CREATIS ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon ( INSA Lyon ), Université de Lyon-Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Hospices Civils de Lyon ( HCL ) -Université Jean Monnet [Saint-Étienne] ( UJM ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Hospices Civils de Lyon ( HCL ) -Université Jean Monnet [Saint-Étienne] ( UJM ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Philips Healthcare, Philips Research [Germany], Philips Research, Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Imagerie et modélisation Vasculaires, Thoraciques et Cérébrales (MOTIVATE), Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Photon, Materials science, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Contrast Media, Coronary Artery Disease, Coronary artery disease, medicine, Humans, Scattering, Radiation, Radiology, Nuclear Medicine and imaging, [ SDV.IB.IMA ] Life Sciences [q-bio]/Bioengineering/Imaging, Photons, Full Paper, business.industry, Compton scattering, General Medicine, medicine.disease, Photon counting, Plaque, Atherosclerotic, Intensity (physics), Coronary arteries, medicine.anatomical_structure, Radiographic Image Interpretation, Computer-Assisted, Tomography, Autopsy, Nuclear medicine, business, Tomography, X-Ray Computed, Artery
Abstract

International audience; Objectives. To evaluate the capabilities of Photon Counting Spectral CT to differentiate components of coronary atherosclerotic plaque based on differences in spectral attenuation and iodine-based contrast agent concentration. Methods. 10 calcified and 13 lipid-rich atheromatous plaques from postmortem human coronary arteries were scanned with a Photon Counting Spectral CT scanner. Individual photons were counted and classified in one of 6 energy bins from 25 to 70 keV.Based on a maximum likelihood approach, maps of Photoelectric Absorption (PA), Compton Scattering (CS) and Iodine Concentration (IC) were reconstructed. Intensity measurements were performed on each map in the vessel wall, the surrounding perivascular fat, the lipid-rich and the calcified plaques. PA and CS values are expressed relative to pure water values. Comparison between these different elements was performed using Kruskal-Wallis tests with pairwise post-hoc Mann-Whitney U tests and Sidak p-values adjustment. Results. Results for vessel wall, surrounding perivascular fat, lipid-rich, and calcified plaques were respectively 1.19+/-0.09, 0.73+/-0.05, 1.08+/-0.14, 17.79+/-6.70 for PA; 0.96+/-0.02, 0.83+/-0.02, 0.91+/-0.03, 2.53+/-0.63 for CS, and 83.3+/-10.1, 37.6+/-8.1, 55.2+/-14.0, 4.9+/-20.0 mmol/l for IC, with significant differences between all tissues for PA, CS and IC (p

Published
2014

5. Deconvolution for limited-view streak artifacts removal: improvements upon an existing approach

Author

Michael Grass, Françoise Peyrin, Vincent Auvray, Loic Boussel, Bo Zhang, Cyril Mory, Philippe Douek, Simon Rit, Dirk Schäfer, Imagerie Tomographique et Radiothérapie, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), MedisysResearch Lab (Medisys), Philips Research, Philips Research [Germany], Imagerie et modélisation Vasculaires, Thoraciques et Cérébrales (MOTIVATE), Service de Radiologie [Hôpital de la Croix-Rousse - HCL], Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), and Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
Artifact (error), Radon transform, business.industry, Iterative method, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Streak, Inverse, Iterative reconstruction, Inverse problem, 01 natural sciences, 030218 nuclear medicine & medical imaging, 010309 optics, 03 medical and health sciences, 0302 clinical medicine, 0103 physical sciences, Computer vision, Artificial intelligence, Deconvolution, business, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, Mathematics
Abstract

International audience; Cardiac C-Arm computed tomography leads to a view-starved reconstruction problem because of electrocardiogram gating. Reconstruction with the Feldkamp, Davis and Kress method (FDK) generates large streak artifacts in the reconstructed volumes, hampering the medical interpretation. In order to remove these artifacts, deconvolution techniques have been proposed. In this paper, we start from a recent inverse filtering method developed for streak artifact removal. Two ways to improve upon this method are described. It is then proposed to replace inverse filtering with an iterative deconvolution scheme. Finally, we show that the iterative deconvolution method can itself be replaced by iterative filtered back projection (IFBP). The IFBP approach is flexible and could be used in a broad range of applications, while the improved inverse filtering approaches are computationally less demanding and better suited for time-critical applications.

Published
2012

6. Robust pose estimation and recognition using non-Gaussian modeling of appearance subspaces

Author

Fabrice Heitz, Pierre Charbonnier, T. Vik, Philips Research [Germany], Philips Research, Laboratoire des Sciences de l'Image, de l'Informatique et de la Télédétection (LSIIT), Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Centre d'études techniques de l'équipement Est (CETE Est), Avant création Cerema, and Cadic, Ifsttar

Subjects
Gaussian, Normal Distribution, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, MODELE STATISTIQUE, Information Storage and Retrieval, 02 engineering and technology, Sensitivity and Specificity, Pattern Recognition, Automated, 03 medical and health sciences, symbols.namesake, 0302 clinical medicine, Imaging, Three-Dimensional, Artificial Intelligence, ALGORITHME, Image Interpretation, Computer-Assisted, 0202 electrical engineering, electronic engineering, information engineering, Mean-shift, TRAITEMENT DES IMAGES, Gaussian process, Pose, Mathematics, Models, Statistical, RECONNAISSANCE DE FORME, business.industry, Applied Mathematics, Cognitive neuroscience of visual object recognition, Reproducibility of Results, Pattern recognition, Visual appearance, Image Enhancement, Active appearance model, ComputingMethodologies_PATTERNRECOGNITION, Computational Theory and Mathematics, [INFO.INFO-TI] Computer Science [cs]/Image Processing [eess.IV], Computer Science::Computer Vision and Pattern Recognition, [INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV], Pattern recognition (psychology), symbols, 020201 artificial intelligence & image processing, Computer Vision and Pattern Recognition, Artificial intelligence, business, 030217 neurology & neurosurgery, Software, Algorithms
Abstract

We present an original appearance model that generalizes the usual Gaussian visual subspace model to non-Gaussian and nonparametric distributions. It can be useful for the modeling and recognition of images under difficult conditions such as large occlusions and cluttered backgrounds. Inference under the model is efficiently solved using the mean shift algorithm.

Published
2007

7. Acceleration of tissue phase mapping by k-t BLAST: a detailed analysis of the influence of k-t-BLAST for the quantification of myocardial motion at 3T

Author

Patrick Etyngier, Robert Manzke, Volker Rasche, Axel Bornstedt, Anja Lutz, G. Ulrich Nienhaus, Department of Internal Medicine II, Universitätsklinikum Ulm - University Hospital of Ulm, Philips Research [Germany], Philips Research, MedisysResearch Lab (Medisys), and Karlsruhe Institute of Technology (KIT)

Subjects
Adult, Male, lcsh:Diseases of the circulatory (Cardiovascular) system, Time Factors, Adolescent, Magnetic Resonance Imaging, Cine, Motion (physics), 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Acceleration, Young Adult, 0302 clinical medicine, Data acquisition, Cardiac motion, Germany, Image Interpretation, Computer-Assisted, [INFO.INFO-IM]Computer Science [cs]/Medical Imaging, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Phase mapping, Medicine(all), Radiological and Ultrasound Technology, business.industry, Research, Heart, Myocardial Contraction, lcsh:RC666-701, Temporal resolution, Dynamic contrast-enhanced MRI, Myocardial motion, Female, Cardiology and Cardiovascular Medicine, Nuclear medicine, business, 030217 neurology & neurosurgery, Biomedical engineering
Abstract

International audience; Background: The assessment of myocardial motion with tissue phase mapping (TPM) provides high spatiotemporal resolution and quantitative motion information in three directions. Today, whole volume coverage of the heart by TPM encoding at high spatial and temporal resolution is limited by long data acquisition times. Therefore, a significant increase in imaging speed without deterioration of the quantitative motion information is required. For this purpose, the k-t BLAST acceleration technique was combined with TPM black-blood functional imaging of the heart. Different k-t factors were evaluated with respect to their impact on the quantitative assessment of cardiac motion. Results: It is demonstrated that a k-t BLAST factor of two can be used with a marginal, but statistically significant deterioration of the quantitative motion data. Further increasing the k-t acceleration causes substantial alteration of the peak velocities and the motion pattern, but the temporal behavior of the contraction is well maintained up to an acceleration factor of six. Conclusions: The application of k-t BLAST for the acceleration of TPM appears feasible. A reduction of the acquisition time of almost 45% could be achieved without substantial loss of quantitative motion information. © 2011 Lutz et al; licensee BioMed Central Ltd. The electronic version of this article is the complete one and can be found online at: http://www.jcmr-online.com/content/13/1/5.

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