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The structural distortion problem of large thin-walled aerospace components has roused much concern on more agile, digitized and cost-efficient precision manufacturing techniques, in particular, designing suitable machining plans according to the real shape of workpieces. To improve the machining accuracy of large thin-walled aerospace components, a methodology of three-dimensional machining allowance modeling and analysis is proposed in this paper. Firstly, the fundamental principles of 3D models matching and alignment between the casting blank and the design part are presented. And by datum transformation from virtual design references to real-world references on casting blanks which are accessible more easily, measuring, positioning and machining the casting blank will be more convenient to realize. Furthermore, the technical character of a large thin-walled aerospace component is considered and a technical framework for 3D machining allowance analysis is given. Finally, the proposed methodology is validated by an experimental study using a typical large thin-walled aerospace component of a hypersonic vehicle. Improvements in accuracy and efficiency performance are realized in comparison with traditional methods.

The combination of near-infrared spectroscopy and pattern recognition methods, including soft independent modeling of class analogy, least squares support machine, and extreme learning machine, was employed for textile fabrics classification. The fabrics of cotton, viscose, acrylic, polyamide, polyester, and blend fabric of cotton-viscose were divided into training and prediction sets (60:60) for developing models and evaluating the classification abilities of the models. The classification accuracy and speed of soft independent modeling of class analogy, least squares support machine, and extreme learning machine were compared. Both least squares support machine and extreme learning machine achieved the classification accuracy of 100% for the prediction set. However, extreme learning machine performed much faster than least squares support machine, which suggested that extreme learning machine may be a promising method for real-time textile fabrics classification with a comparable accuracy based ...

Ethnopharmacological relevance The calyxes and fruits of Physalis alkekengi L. var. franchetii (Mast.) Makino (Physalis Calyx seu Fructus), have been widely used in traditional and indigenous Chinese medicines for the therapy of cough, excessive phlegm, pharyngitis, sore throat, dysuria, pemphigus, eczema, and jaundice with a long history. Aim of the review The present review aims to achieve a comprehensive and up-to-date investigation in ethnomedical uses, phytochemistry, pharmacology, and toxicity of P. alkekengi var. franchetii, particularly its calyxes and fruits. Through analysis of these findings, evidences supporting their applications in ethnomedicines are illustrated. Possible perspectives and opportunities for the future research are analyzed to highlight the gaps in our knowledge that deserves further investigation. Material and Methods Information on P. alkekengi var. franchetii was collected via electronic search of major scientific databases (e.g. Web of Science, SciFinder, Google Scholar, Pubmed, Elsevier, SpringerLink, Wiley online and China Knowledge Resource Integrated) for publications on this medicinal plant. Information was also obtained from local classic herbal literature on ethnopharmacology. Results About 124 chemical ingredients have been characterized from different parts of this plant. Steroids (particularly physalins) and flavonoids are the major characteristic and bioactive constituents. The crude extracts and the isolated compounds have demonstrated various in vitro and in vivo pharmacological functions, such as anti-inflammation, inhibition of tumor cell proliferation, antimicrobial activity, diuretic effect, anti-diabetes, anti-asthma, immunomodulation, and anti-oxidation. Conclusions P. alkekengi var. franchetii is an important medicinal plant for the ethnomedical therapy of microbial infection, inflammation, and respiratory diseases (e.g. cough, excessive phlegm, pharyngitis). Phytochemical and pharmacological investigations of this plant definitely increased in the past half century. The chemical profiles, including ingredients and structures, have been adequately verified. Modern pharmacological studies supported its uses in the traditional and folk medicines, however, the molecular mechanisms of purified compounds remained unclear and were worth of further exploration. Therefore, the researchers should be paid more attention to a better utilization of this plant.

This paper aims at getting a way to obtain the suitable track tension by analyzing a heavy tracked vehicles driving prototype which is consisted of the sprocket and the meshing tracks. First, by analyzing the force state in the driving part in the multi-body dynamics simulation tool: RecurDyn, a critical condition to judge the peel-off of tracks in heavy tracked vehicle is proposed. Second, by comparing the different models built in RecurDyn, an ideal track distribution around the sprocket is obtained and also the relationship between the driving torque and the track tension under that ideal situation is concluded. Third, basing on the data from the simulation, the force state of each track meshed with the sprocket is analyzed, and an assumption about the proportion between each tracks upper and bottom pulling force is proposed.

In this paper, the Urea-SCR system is first introduced; then change of the urea solution concentration under different temperatures with time lapsing is given. Meanwhile, conditions for the urea crystallization are analyzed and SCR converter adaptability is tested under high sulfur environment on engine test bench. As the efficiency of NOx conversion is not significantly reduced after aging and the activity of the catalyst is very little damaged by dense sulfur content in fuel, SCR catalyst is able to adapt to the application of high-sulfur-contained fuel environment in our country.

In order to fulfill future emission standards for middle and heavy-duty vehicles like state Ⅳ and Ⅴ, advanced measures on exhaust gas and engine functionality are required. Selective Catalytic Reduction (SCR) technology is the unique technology currently which can improve the emission and reduce fuel consumption simultaneously. Firstly the reductants and its chemical reactions, SCR system configurations and its working principle and urea dosing control strategy are introduced. Then tests are conducted on a diesel engine with SCR system at bench. The results of ESC cycle show that NOx emission is decreased by more than 67% with the open-loop control strategy. Additionally, the urea and fuel consumption and ammonia leakage have been compared and analyzed respectively, the experiment data indicates that the urea water solution consumption ratio is only 5.7% of fuel for this SCR system, while its average ammonia slip is below 5 ppm.

In order to analyze the performances of direct driven PMSG, an optimal power control model which includes maximum power extraction control model under low wind speed and pitch angle control model under high wind speed is established. The concept of the model is analyzed in a 1.5 MW direct drive variable speed permanent magnet synchronous generator (D-PMSG) WECS with back-to-back IGBT frequency converter. Vector control of the generator side rectifier is realized in the grid voltage vector reference frame. Confirmation of models and control schemes is demonstrated by using the EMTDC/PSCAD environment.

According to nondestructive testing principle for the terahertz time domain spectroscopy Imaging, using digital image processing techniques, through Terahertz time-domain spectroscopy system collected images and two-dimensional datas and using a range of processing methods, including selecting regions of interest, contrast enhancement, edge detection, and defects being detected. In the paper, Matlab programming is been use to defect recognition of Terahertz, by figuring out the pixels to determine defects defect area and border length, roundness, diameter size. Through the experiment of the qualitative analysis and quantitative calculation of Matlab image processing, this method of detection of defects of geometric dimension of the sample to get a better result.

Prostaglandin E2 was successfully incorporated into low molecular weight polylactic acid microcapsules. The size distribution of the microcapsules ranges from 20 to 50 micron. The microcapsules released drug continuously up to three days in vitro. The galactosamine induced fulminant hepatic failure rats model was used. 36 hours after the injection of galactosamine, those rats in grade II coma were chosen and pairs were matched for comparable degree of coma. Then each of the pair was randomly selected as control or treated. Each rat in the treated group received an intraperitoneal injection of PGE2 microcapsules containing 0.55 mg of PGE2. The control received blank PLA microcapsules only. The survival rate of the treated group was 40% compared to 10% in the control group. There was a significant (P less than 0.05) increase in the survival rate in the treated group.

Background Chronic obstructive pulmonary disease (COPD) is a major public health problem and gives arise to severe chronic morbidity and mortality in the world. Inflammatory response and oxidative stress play dominant roles in the pathological mechanism of COPD, and have been regarded to be two important targets for the COPD therapy. Traditional Chinese medicines (TCMs) possess satisfying curative effects on COPD under guidance of the TCM theory in China, and merit in-depth investigations as a resource of lead compounds. Methods One hundred ninety-six of TCMs were collected, and extracted to establish a TCM extract library, and then further evaluated for their potency on inhibitions of oxidative stress and inflammatory response using NADP(H):quinone oxidoreductase (QR) assay and nitric oxide (NO) production assay, respectively. Results Our investigation observed that 38 of the tested TCM extracts induced QR activity in hepa 1c1c7 murine hepatoma cells, and 55 of them inhibited NO production in RAW 264.7 murine macrophages at the tested concentrations. Noteworthily, 20 of TCM extracts simultaneously inhibited oxidative stress and inflammatory responses. Conclusion The observed bioactive TCMs, particularly these 20 TCMs with dual inhibitory effects, might be useful for the treatment of COPD. More importantly, the results of the present research afford us an opportunity to discover new lead molecules as COPD therapeutic agents from these active TCMs. Electronic supplementary material The online version of this article (doi:10.1186/s12906-016-1347-y) contains supplementary material, which is available to authorized users.