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Objectives. Bellidifolin (BEL) is one type of tetraoxygenated xanthone that is particularly found in Swertia and Gentiana (Gentianaceae). Despite its broad range of pharmacological activities, it is still unclear whether BEL could be used for lung cancer treatment. Hence, we presently demonstrate the roles of BEL towards the proliferative inhibition of the prototypical A549 lung cancer cells. Materials and Methods. The antiproliferative activity of BEL was initially verified by cellular experiments. A network pharmacology method was then pursued to assess BEL potential molecular targets from the platform for pharmacological analysis of Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). Disease enrichment of potential targets and construction of compound-target-disease network maps were performed based on a total of 20 diseases. Two core targets related to the BEL-mediated effect in A549 cells were obtained by importing potential targets into a protein-protein interaction database (STRING) and also analyzing respective data of related targets into this database. Last, these core targets were examined by in vitro analysis and molecular docking. Results. CCK8 assays indicated that treatment with 50–100 μm BEL had an inhibitory effect on the proliferation of human A549 lung cancer cells, whereas this effect was time- and concentration-dependent. As control, treatment with 50–100 μm BEL did not inhibit the proliferation of normal lung epithelial cells (BEAS-2b cell line). H&E staining of BEL-treated A549 cells showed that, upon an increase of drug concentration, nuclear condensation and fragmentation were largely observed. Cell cycle analysis showed that in vitro treatment with 75–100 μm BEL could block A549 cells in S and G2 phases. Western blot analyses showed that after 72 hours of BEL treatment, the level of caspase-8/3 in A549 cells increased, and the level of PARP1 decreased in a dose-dependent manner. Network pharmacology analysis also indicated that lung cancer was the major disease susceptible to BEL treatment. At the same time, STAT3 and COX-2 were identified as two core targets of BEL in lung cancer treatment. Functional analyses further revealed that the cytotoxicity effect of BEL in A549 cells potentially involved the STAT3/COX-2 pathway. Moreover, molecular docking analysis indicated that BEL structure properly matches with COX-2 and STAT3 in space shape, thus illustrating the putative molecular mechanism of BEL’s anticancer effect. Conclusions. Based on a series of in vitro analyses, network pharmacology, and molecular docking, the potential mechanism involving the antiproliferative and cytotoxic effects of BEL in lung cancer cells was investigated. Our study may help providing some theoretical basis for the discovery of novel phytotherapy drugs applicable for the treatment of lung cancer.

The gas generation features of coals at different maturities were studied by the anhydrous pyrolysis of Jurassic coal from the Minhe Basin in sealed gold tubes at 50 MPa. The gas component yields (C1, C2, C3, i-C4, n-C4, i-C5, n-C5, and CO2); the δ13C of C1, C2, C3, and CO2; and the mass of the liquid hydrocarbons (C6+) were measured. On the basis of these data, the stage changes of δ13C1, δ13C2, δ13C3, and δ13CO2 were calculated. The diagrams of δ13C1–δ13C2 vs ln (C1/C2) and δ13C2–δ13C1 vs δ13C3–δ13C2 were used to evaluate the gas generation features of the coal maturity stages. At the high maturity evolution stage (T > 527.6 °C at 2 °C/h), the stage change of δ13C1 and the CH4 yield are much higher than that of CO2, suggesting that high maturity coal could still generate methane. When T 2 is generated by breaking bonds between carbons and heteroatoms. The reaction between different sources of coke and water may be the reason for the complicated stage change in $$\delta^{{{13}}} {\text{C}}_{{{\text{CO}}_{{2}} }}$$ δ 13 C CO 2 when the temperature was higher than 455 °C. With increasing pyrolysis temperature, δ13C1–δ13C2 vs ln (C1/C2) has four evolution stages corresponding to the early stage of breaking bonds between carbon and hetero atoms, the later stage of breaking bonds between carbon and hetero atoms, the cracking of C6+ and coal demethylation, and the cracking of C2–5. The δ13C2–δ13C1 vs δ13C3–δ13C2 has three evolution stages corresponding to the breaking bonds between carbon and hetero atoms, demethylation and cracking of C6+, and cracking of C2–5.

The wide application of artificial intelligence in the field of translation has changed the traditional mode of translation industry. Through market research and data analysis, it is found that translation education in the age of artificial intelligence also faces many challenges, such as the outdated hardware and software facilities, the traditional training mode, the shortage of translation technology teachers and the limited teaching material resources. To solve these problems, colleges should have the courage to make changes in laboratory construction, talent training mode, teachers' technology teaching ability and textbook compilation.

Introgressing one-eighth of synthetic hexaploid wheat genome through a double top-cross plus a two-phase selection is an effective strategy to develop high-yielding wheat varieties. The continued expansion of the world population and the likely onset of climate change combine to form a major crop breeding challenge. Genetic advances in most crop species to date have largely relied on recombination and reassortment within a relatively narrow gene pool. Here, we demonstrate an efficient wheat breeding strategy for improving yield potentials by introgression of multiple genomic regions of de novo synthesized wheat. The method relies on an initial double top-cross (DTC), in which one parent is synthetic hexaploid wheat (SHW), followed by a two-phase selection procedure. A genotypic analysis of three varieties (Shumai 580, Shumai 969 and Shumai 830) released from this program showed that each harbors a unique set of genomic regions inherited from the SHW parent. The first two varieties were generated from very small populations, whereas the third used a more conventional scale of selection since one of bread wheat parents was a pre-breeding material. The three varieties had remarkably enhanced yield potential compared to those developed by conventional breeding. A widely accepted consensus among crop breeders holds that introducing unadapted germplasm, such as landraces, as parents into a breeding program is a risky proposition, since the size of the breeding population required to overcome linkage drag becomes too daunting. However, the success of the proposed DTC strategy has demonstrated that novel variation harbored by SHWs can be accessed in a straightforward, effective manner. The strategy is in principle generalizable to any allopolyploid crop species where the identity of the progenitor species is known.

The phase characteristics of petroleum fluids are directly related to the hydrocarbon accumulation, and through exploration and development, the evolution process of hydrocarbon generation from coal is found to be complex, with variable fluid phases. To explore the relationship between the hydrocarbon generation process and fluid phase evolution of the coal, we derive the kinetic parameters for the gaseous hydrocarbons and methane generated from a series of closed-system laboratory pyrolysis tests of a Jurassic coal from the Minhe Basin and established a phase evolution diagram of the coal-generated fluids and the corresponding geological conditions. The study shows that with a fixed frequency factor of 1.0 × 10 14 /s, the mean values of activation energies of C 1 and C 1–5 are 64.55 kCal/mol and 63.93 kCal/mol, respectively. The phase of the coal-generated hydrocarbon fluids produced under geological conditions shows that an undersaturated oil phase or an oil–gas phases is possible when Easy%Ro 2.05. The hydrocarbon generated from the Jurassic coal of the Minhe Basin started as an oil phase in the Early Cretaceous, and the fluid phase may have changed from oil phase to oil–gas phases in the late Early Cretaceous, The fluid changed to gas phase after the Miocene. Additionally, the source rock is still in the stage of gas generation currently.

How the human brain does recognition is still an open question. No physical or biological experiment can fully reveal this process. Psychological evidence is more about describing phenomena and laws than explaining the physiological processes behind them. The need for interpretability is well recognized. This paper proposes a new method for supervised pattern recognition based on the working pattern of implicit memory. The artificial neural network (ANN) is trained to simulate implicit memory. When an input vector is not in the training set, the ANN can treat the input as a “do not care” term. The ANN may output any value when the input is a “do not care” term since the training process needs to use as few neurons as possible. The trained ANN can be expressed as a function to design a pattern recognition algorithm. Using the Mixed National Institute of Standards and Technology database, the experiments show the efficiency of the pattern recognition method.

With the increasingly fierce global economic competition and the continuous escalation of competition pressure in the workplace, as an important positive psychological element, psychological capital can not only enhance the competitive advantage of individuals and organizations, but also effectively alleviate and improve people's unhealthy physical and mental conditions. In order to accurately grasp the current status of psychological capital research in China, this paper uses VOSviewer information visualization software to conduct a comprehensive analysis of the current research status of 280 core studies in the CSSCI database based on the basic principles of scientometrics and information visualization, including time distribution and core author relationships network, keyword co-occurrence, author co-citation network, etc. It turns out that the research hotspots are mainly concentrated in four areas: The positive role of psychological capital in promoting the mental health of specific groups, the research on the mechanism of employee psychological capital in organizational management, the research on the impact of psychological capital on the work attitude of migrant workers, the research on the mechanism of psychological capital in college students. This result can provide some guidance for future researchers to clarify and carry out their own psychological capital research.

With the continuous advancement of educational informatization and the rapid development of artificial intelligence, deep learning, as an efficient learning method, will be constantly integrated into the development of higher education. In order to accurately grasp the current research status of deep learning in China, this paper based on the basic principle of scientometrics and information visualization, using VOSviewer information visualization software to comprehensively analyze the research status of 342 core studies in CSSCI database, including time distribution, core authors relationship network, keywords co-occurrence, literature cited network, etc. The results show that the research focuses mainly on five aspects: teaching practice based on traditional deep learning, principle and algorithm of deep learning technology, deep learning based on educational informationization, research on internal mechanism of deep learning, and application of deep learning technology. This result can provide some guidance for future researchers to clarify and carry out their own deep learning research.

With the advent of boundaryless career and the continuous advancement of the new college entrance examination reform, theoretical and practical researchers pay more and more attention to professional career. In order to accurately grasp the current status of professional career research, CiteSpace (i.e. an information visualization software) was utilized to conduct objective quantitative analysis on 572 core research literatures of professional career, based on the basic principles of scientometrics and information visualization. The literatures were derived from Chinese Social Sciences Citation Index (CSSCI) database, publication dates ranged from 1998 to 2018 and the corresponding knowledge maps were gained from the analyses finally.

In this paper, the dynamic modelling and simulation of a batch-wise solar driven liquid desiccant air conditioning system (SLDACS) using TRNSYS platform is presented. The dynamic models of dehumidifier and regenerator are developed on the strength of discretization of coupled heat and mass transfer process and depicted by customized component of TRNSYS. Other devices, such as solar thermal subsystem, chiller, pump, are modeled by the standard TRNSYS components. With the developed dynamic SLDACS model, the influence of parameters on system performance are analyzed and investigated to choose the proper system design parameter, collect area, and operational parameters, such as solution flowrate, hot water flowrate and chilled water temperature are discussed. Through this work, we get a better understanding of dynamic performance of the SLDACS, and hope to give a guide to optimal dynamic control strategy in further research.

Laser spectroscopy based techniques have the advantages of high sensitivities, high selectivities, non-invasiveness and in situ, real-time observations. They are widely used in numerous fields, such as environmental monitoring, life science, medical diagnostics, manned space flight, and planetary exploration. Owing to the merits of low cost, compact volume and strong environment adaptability, quartz-enhanced photoacoustic spectroscopy (QEPAS) based sensing is an important laser spectroscopy-based method of detecting the trace gas, which was invented in 2002. Detection sensitivity is a key parameter for gas sensors because it determines their real applications. In this paper, focusing on the detection sensitivity, the common methods for QEPAS are summarized. High power laser including amplified diode laser by erbium doped fiber amplifier (EDFA), and quantum cascade laser are used to improve the excitation intensity of acoustic wave. The absorption line of gas molecules located at the fundamental bands of mid-infrared region is adopted to increase the laser absorption strength. Micro-resonator is employed to enhance the generated acoustic pressure by forming a standing wave cavity. Quartz tuning forks (QTFs) with low resonant frequency are used to increase the accumulation time of acoustic energy in itself. Multi-pass strategy is utilized to amplify the action length between laser beam and target gas in the prongs of QTF. The advantages and disadvantages of the above methods are discussed respectively. For the issues in real applications, the all-fiber strucure in near-infared region and mid-infrared region and miniaturization using three-dimensional(3D) printing technique for QEPAS sensor are summarized. A QEPAS technique based multi-gas sensor is used to quantify the concentration of carbon monoxide (CO), carbon dioxide (CO2), hydrogen cyanide (HCN), and hydrogen chloride (HCl) for post-fire cleanup aboard spacecraft, which is taken for example for the real application.Finally, the methods of further improving the sensitivity of QEPAS sensor are proposed.

Large-scale cultivation of Aconitum carmichaelii Debeaux has been carried out on medicinal plant farms in western China for over 1000 years. After detoxification, the fleshy roots are officially used as aconite in herbal medicine.

In this paper, the optical fiber sensing technology is taken as the research object. Firstly, according to the demand of the sensing layer of the power Internet of things, a transmission line environment online monitoring system is proposed based on the multi risk monitoring of external breakage, fire, icing, galloping and so on of the cable (overhead line), the composition and deployment of the monitoring system are introduced. Secondly, based on the research of temperature field and stress field distribution of optical fiber, combined with big data and artificial intelligence, the important environmental parameters of the line can be monitored. Finally, taking different monitoring scenarios as examples, this paper expounds the different monitoring functions of the environmental monitoring system of the Internet of things for transmission lines, which provides useful reference for environmental monitoring of transmission lines.

Differentiation is important to business competition, particularly when value propositions, technologies, and markets are converging to blur the boundaries between industries and create new hybridized segments at their intersections. Convergence from new technologies presents new packages of performance attributes and for underserved or non-consumers implies new sets of value propositions, allowing both challengers and disruptors to create new markets ignored or untapped by their competitors. Taking nutraceuticals as an example, this paper uses a case study to investigate differentiation under convergence of the food, biotechnology, and pharmaceutical industries. We study a startup in Taiwan, GWOXI, to examine how it took advantage of the convergence of technologies from the supply side, and that of markets from the demand side, to differentiate and defend itself against incumbents and other new entrants. As opposed to previous works that put more emphasis on the attributes of products themselves, we pay special attention to legitimating strategies that affect consumers' perceptions of product attributes. We propose three legitimating strategies - theorization, authorization, and validation - which are instructive for new product development and marketing in the nutraceuticals industry in particular and in other converged industries in general.

In Autonomous Driving (AD), detection and tracking of obstacles on the roads is a critical task. Deep-learning based methods using annotated LiDAR data have been the most widely adopted approach for this. Unfortunately, annotating 3D point cloud is a very challenging, time- and money-consuming task. In this paper, we propose a novel LiDAR simulator that augments real point cloud with synthetic obstacles (e.g., cars, pedestrians, and other movable objects). Unlike previous simulators that entirely rely on CG models and game engines, our augmented simulator bypasses the requirement to create high-fidelity background CAD models. Instead, we can simply deploy a vehicle with a LiDAR scanner to sweep the street of interests to obtain the background point cloud, based on which annotated point cloud can be automatically generated. This unique "scan-and-simulate" capability makes our approach scalable and practical, ready for large-scale industrial applications. In this paper, we describe our simulator in detail, in particular the placement of obstacles that is critical for performance enhancement. We show that detectors with our simulated LiDAR point cloud alone can perform comparably (within two percentage points) with these trained with real data. Mixing real and simulated data can achieve over 95% accuracy., Comment: 10 pages

To adjust the energy structure, protect the environment and deal with climate change, China has proposed that non-fossil energy would constitute 15 percent of the total energy consumption at the end of the “13th Five-Year Plan” period (2016–2020), and the use of biomass would account for 4 percent of primary energy consumption. Firstly, the current situation, the internal environment and the external environment of the biomass direct combustion power generation are analyzed. Then, the financial model of biomass direct combustion power generation project is established, and contrasts with other major new energy projects are carried out in terms of operation models, opportunities and risks so as to explore the investment features of this project in depth. Finally, appropriate investment strategies are proposed with respect of the investors, and policy recommendations for the development of the industry are attempted as well.

The optical design based on foci mapping ellipse flow-patch method has many advantages, such as clear geometric meaning, design flexibility and explicit method of optimization, but there is a drawback that the surface is not smooth. In order to sew up each ellipse flow-patch on the freeform reflector smoothly, the surface of reflector started from one point on the edge and a smooth ellipse flow-patch was built in the direction, then the discontinuity in the direction could be reduced by the energy adjusting method. The time consumption for the surface reconstruction from 40 000 ellipsoid pieces with this method is only about 2 min. The free-form surface cannot only ensure the energy distributed equally, but also improve the smoothness greatly.

Background: Intrauterine growth restriction (IUGR) is considered to be a major risk for cerebral palsy and disability after birth. However, IUGR lacks effective treatment strategies. We aimed to establish a rat model of bilateral uterine artery ischemia-reperfusion as a surgical model of IUGR.Methods: At the 17th day of pregnancy, six Sprague-Dawley (SD) rats were randomly divided into sham (NOR) and growth restriction (GR) groups. In the GR groups, four small artery clamps were used to occlude the uterine vessels near the lower and upper ends of the bilateral horns for 25 min; then, the clamps were removed, and the horns were placed back into the abdomen cavity. In the sham-operated animals, the uterine horns were exposed for 25 min without artery clamping. After labour and delivery, the death rates and weights during the first 8 days of newborn rats were recorded. A pathological examination was performed with hematoxylin-eosin staining (HE) staining and terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling staining (TUNEL) on 4-day-old and 8-day-old brain tissues of the newborn rats.Results: The mortality within the first 24 h of rats in the GR group were increased (66.7% vs 0.0%), and their daily weights within the first 8 postnatal days were decreased. In addition, the karyopyknosis percentages of 4-day-old and 8-day-old rats were increased (4-day-old: 45% vs 11%; 8-day-old: 34.7% vs 5.3%), and the numbers of TUNEL-positive cells were increased (4-day-old: 110 vs 12.7; 8-day-old: 146.7 vs 4).Conclusions: This model of foetal IUGR produced a decrease in weight, an increase in the death rate within 24 h and an increase in apoptosis in newborn rats. The establishment of the model was successful. Citation: Min Diao, Hao Li, Yi Qu, Hui Liu, Yu-Shan Ma, Xue-Mei Lin. A model of intrauterine growth restriction was induced by bilateral uterine vessel clamping in pregnant rats. J Anesth Perioper Med 2017;4: 101-7. doi:10.24015/JAPM.2017.0026This is an open-access article, published by Evidence Based Communications (EBC). This work is licensed under the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium or format for any lawful purpose. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Currently, many defects have appeared in wind and solar power generation systems. Utilizing the complementary of wind and solar power generation will break the bottleneck of new energy development. How to select the site of wind/solar hybrid power station scientifically is a primary problem. First, the framework of the indicator system is obtained from the literature review and refined according to the resources evaluation standards and different perspectives of the various scholars. Then this paper selects seven wind/solar hybrid power stations which have been put into operation as the case study, weights the indicators through the method of order relations, and evaluates these seven regions via ELECTRE-II. The conclusions are consistent with the related research findings and have better correctness, proving the feasibility and effectiveness of the method. It may provide some theoretical basis for the macro-site selection of wind/solar hybrid power station.

The vertical, steady-state breeze vibration of transmission line with dampers attached are studied using FEM analysis. The lines are simulated by cable element, the dampers by mass element and beam element. The parameters of FEM emulation mode such as breeze vibration force, the conductor self-damping and dampers damping are emphasized by the energy equivalent theory. The breeze vibration force induced by vortex is educed by wind power curve, the hysteresis damping and friction damping of conductor and damper are translated into viscous damping. Results of the FEM emulation show the calculation accuracy of natural frequency of dampers, and prove that it can effectively restrain breeze vibration of transmission lines by installing dampers. The method lays foundation for further research on protecting breeze vibration of transmission lines.

The article have described the optimization of the engine performance problem as nonlinear multi-objective programming, and have analyzed the operation principle of the variable cycle engine, made models of maximum thrust , maximum unit thrust, minimum oil consumption, and then adopts the genetic algorithm to solve the model, gained the guide vane angle of CDFS,the guide vane angle of low-pressure.Turbine and the nozzle throat area when the performance is optimal . It is a problem about multi-objective optimization, obtained a series of satisfactory solution and then selected a set of approximate optimal solution as the final argument. Lastly, The matlab software is used to illustrate the effectiveness of the results.

This paper is mainly focused on the analysis of the subspan oscillation to bundled conductors.The mechanics of subspan oscillation were analyzed. Considering anti-adsorption conditions and the amplitude 1imitations of sub-conductors, the calculating methods of largest subspan distance of bundle conductors were given. The mechanics of anti-subspan oscillation of spacer dampers was analyzed and a mechanical model of damping spacer damper was established. By calculating an engineering example, a real problem was calculated and evaluated, which was validated to be reasonable. Finally, a suit of calculation and simulation software was developed to facilitate the designers.

Exciton (or spin) statistics is a physical principle based on the statistics of spin multiplicity. In electroluminescence, injected electrons and holes have randomized spin states, and usually form singlet or triplet excitons in the ratio of 1:3. Exciton statistics determines that the upper limit of internal quantum efficiency is 25% in fluorescent devices, since only singlet exciton can decay radiatively. However, both experimental and theoretical evidence indicate that the actual efficiency can exceed the exciton statistics limit of 25% by utilizing materials with special electronic structure and optimized device structures. These results bring light to break through the exciton statistics limit and develop new-generation fluorescent materials with low cost and high efficiency. Recently, the exciton statistics, which has attracted great attention in the past decade, is being rejuvenated due to the discovery of some fluorescent materials with abnormally high efficiencies. In view of their significance in theoretical research of organic semiconductors and developing new-generation OLED materials, such materials are widely investigated in both academic institutions and industry. Several key issues still require further clarification for this kind of materials, such as the molecular design concepts. Herein, we review the progress of the materials with efficiency exceeding the exciton statistics limit, and the routes to improve exciton utilization efficiency. In the end, we present an innovative pathway to fully harvest the excitons in fluorescent devices, namely, “hot exciton” model and relevant fluorescence material with hybridized local and charge-transfer (HLCT) excited state.

Objective We aim to investigate the effect of manual lymphatic drainage in combination with functional exercise in the recovery from modified radical mastectomy. The outcome measurements are the incidence of lymphedema, function of upper limb, pain and life quality after operation. Methods We included 198 patients diagnosed with breast cancer in pathological examination and having received modified radical mastectomy in the First Affiliated Hospital of Jinan University from January 2016 to December 2017. The patients were randomized into experimental and control groups with 99 cases in each group. The control group was given guidance on functional exercise and health education. The control group, based on the treatment of control group was also given manual lymphatic drainage and the patients or their family members were ensured to master the practice of manual lymphatic drainage so that they could perform it after discharge. The incidence of lymphedema, pain, range of motion of shoulder joint and life quality among patients at three, six, twelve months postoperatively were recorded. Results There was no significant difference in the incidence of lymphedema at three months after operation (P 0.05). Conclusions Manual lymphatic drainage in combination with functional exercise is effective to reduce the incidence of lymphedema, difficulty in motion of shoulder joint and pain and numbness of affected limb, and improve life quality after breast cancer operation.

Objective We aim to explore the clinical effect of manual lymph drainage as a complex decongestive therapy on improving upper limb lymphedema after breast cancer operation. Methods Manual lymph drainage was performed on 28 patients with lymphedema after receiving breast cancer operation. Circumference measurement was done at transverse palmar crease, transverse carpal crease, 10cm below transverse cubital crease, 10 cm above transverse cubital crease and 20 cm above transverse cubital crease at the first day before treatment and 1 day, 1 week, 2 weeks and 3 weeks after treatment. The movement of shoulder joints, pain and numbness of patients were recorded. Results After 3 weeks of manual lymph drainage, the circumference at transverse palmar crease, transverse carpal crease, 10cm below transverse cubital crease, 10 cm above transverse cubital crease and 20 cm above transverse cubital crease was significantly lower than that before treatment. The detumescence of the middle segment of forearm (10 cm below transverse cubital crease) was better than that of the middle segment of upper arm (10 cm above transverse cubital crease) and the superior segment of upper arm (20 cm above transverse cubital crease) with a significant difference (P

A 3Dedge surface denoised tracking algorithm is proposed to reconstruct high accuracy edge surfaces from the noisy industrial CT slices based on the 3Dfractional-order integral.The 2Dfractional-order integral method has effective denoising ability to preserves the texture detail of the image,and it has low computation complexity and easy implementation due to the filtering mask.In this paper,the 2Dfractional-order integral has been extended to three-dimensional images,its 3Dcontinuous theory and the discrete filtering masks are also proposed,we call it volumetric fractional-order integral.Since the Laplacian operator shows the sensitivity to the noise,the traditional 3Dedge surface tacking method cannot extract the high precision 3Dedge surface from noisy slice images effectively,the 3Dfractional-order integral is added to the tracking method to overcome the existed shortcoming.Our method is able to detect and extract the 3Dedge surface of sub-voxel accuracy from the 2Dnoisy industrial CT slice images.The experiments have reported very encouraging results according to signal noise ratio and visual effect by comparing it to the tacking method based on 3DGaussian denosing method.

Driven by the proliferation of data traffic and requirement of user experience improvement, mobile wireless network is evolving towards heterogeneous networks (HetNet). The telecom operator is experiencing unprecedented challenges on service maintenance and operational expenditure, which drives the demand for realizing automation in current heterogeneous networks. Cell outage detection is a functionality aiming to automatically detect and locate outages that occur in radio networks due to unexpected failures. Our work presents an automated cell outage detection mechanism in heterogeneous networks in which a clustering algorithm named Dynamic Affinity Propagation (DAP) is introduced. Minimization of drive test (MDT) measurements are collected and dimensionality reduced during regular operation and then fed into the clustering algorithm to find anomaly cells. The proposed mechanism has been implemented in the HetNet simulation environment, through which we have successfully detected the configured cell outages and located the specific outage areas.

peer-reviewed An investigation into a novel in-vivo PMMA (polymethyl methacrylate) plastic fiber-optic dosimeter for monitoring low doses of ionizing radiotherapy radiation in real time and for integrating measurements is presented. The fabricated optical fiber tip possessed an embedded structure. A scintillation material, terbium-doped gadolinium oxysulfide (Gd2O2S:Tb), capable of emitting visible light at around 545 nm which is ideal for transmission through the PMMA when exposed to ionizing radiation was embedded in the PMMA plastic fiber. The dose rate of incident ionizing radiation is measured by analyzing the signal intensity emitted from the scintillation material which propagates through the fiber to a distal MPPC (multi-pixel photon counter). The dosimeter exhibits good repeatability with an excellent linear relationship between the fiber-optic dosimeter output and the absorbed radiation dose with an outstanding isotropic response in its radial angular dependence. PUBLISHED peer-reviewed

An impact rotary motor based on a bulk piezoelectric torsional actuator with grooved helical electrodes is proposed. The prototype actuator, with dimensions of Φ 8 mm × 10 mm, produces a maximum torsional angle of 0.035° with a driving voltage of 2200 Vp-p. Its first torsional resonant frequency is 32 kHz with the fixed-free boundary condition. The rotational speed of the developed motor is proportional to both the amplitude and the frequency of the driving voltage in low frequency range. With a saw-shaped driving voltage of 1400 Vp-p at 8 kHz, the motor can rotate at a speed of 22.5 r/min with a braking torque of 0.1 mN·m, and the stall torque can reach up to 1.6 mN·m. Although its maximum efficiency is less than 0.1%, the motor produces a rather small step angle with a large driving torque. It is suitable for ultrahigh precision positioning.

Silicon photomultipliers (SiPMs) are a new generation of semiconductor-based photon counting devices with the merits of low weight, low power consumption and low voltage operation, promising to meet the needs of space particle physics experiments. In this paper, comparative studies of SiPMs and traditional vacuum photomultiplier tubes (PMTs) have been performed regarding the basic properties of dark currents, dark counts and excess noise factors. The intrinsic optical crosstalk effect of SiPMs was evaluated.

The present paper describes the design and simulation results of a position-sensitive charged particle detector based on the Double Sided Silicon Strip Detector (DSSSD). Also, the characteristics of the DSSSD and its testing result were are discussed. With the application of the DSSSD, the position-sensitive charged particle detector can not only give particle flux and energy spectra information and identify different types of charged particles, but also measure the location and angle of incident particles. As the detector can make multiparameter measurements of charged particles, it is widely used in space detection and exploration missions, such as charged particle detection related to earthquakes, space environment monitoring and solar activity inspection.

In a conventional system of quartz-enhanced photoacoustic spectroscopy (QEPAS), the size of block-like optical collimation focusing lens group is difficult to reduce, and the structural stability is poor, which makes it hard to adapt itself to some special conditions, such as narrow space and vibrating circumstance. Based on this situation, in this research the fiber evanescent wave technique is combined with QEPAS. Therefore, trace gas detection for acetylene (C2H2) based on an all-fiber structural QEPAS system is developed. To obtain the characteristics of fiber evanescent wave, the optical distribution of micro structural fiber is simulated and the evanescent wave power ratio is calculated based on the COMSOL Multiphysics software. In order to increase the QEPAS 2f signal amplitude, the optical path between fiber taper and quartz tuning fork (QTF) and the laser wavelength modulation depth are optimized. In addition, two kinds of QTFs with different resonant frequencies are optimized. Finally, a QTF with a lower resonant frequency of 30.720 kHz is adopted as the acoustic wave transducer, and a minimum detection limit (MDL) of 6.2510-4 (volume fraction) is obtained with a laser wavelength modulation depth of 0.24 cm-1. To investigate the evanescent wave power of micro structural fiber, the fiber taper diameter is measured by a scanning electron microscope. Subsequently, by combining the diameter of fiber taper with the theoretical calculation results, we determine an evanescent wave power of 455.9 W, and the normalization of noise equivalent absorption (NNEA) which indicates the sensor sensitivity is 4.1810-7 cm-1WHz-1/2.

The aim of the study was to investigate the sleep patterns and the prevalence and types of sleep problems among urban Chinese children under 5 years of age. Data were gathered on 14,883 children selected by stratified random sampling from 12 cities, using the Children's Sleep Status Questionnaire (CSSQ). The parents were asked about their children's average sleep time in a 24-hour period and common sleep problems noted during the past month. Of this sample, 20.3% of the children were reported as suffering from at least one of the 14 sleep disturbances studied. The five most common sleep problems were difficulty falling asleep (found in 7.5% of pre-school children), nocturnal awakening (4.9%), bruxism (4.7%), snoring (4.4%) and mouth breathing (3.0%). Excluding the cases with sleep disorders, the average sleep time over a 24-h period progressively shortened with age, from 15.8 hours at 1 month to 13.1 hours at 6 months, 12.6 hours at 12 months, 12.0 hours at 2 years, and 11.3 hours at 5 years. The number o...

Organic crystals constructed by pi-conjugated molecules have been paid great attention to in the field of organic optoelectronic materials. The superiorities of these organic crystal materials, such as high thermal stability, highly ordered structure, and high carrier mobility over the amorphous thin film materials, make them attractive candidates for optoelectronic devices. Single crystal with definite structure provides a model to investigate the basic interactions between the molecules (supramolecular interaction), and the relationship between molecular stacking modes and optoelectronic performance (luminescence and carrier mobility). Through modulating molecular arrangement in organic crystal, the luminescence efficiency of organic crystal has exceeded 80% and carrier mobility has been up to the level of 10 cm2·V−1·s−1. Amplified stimulated emission phenomena have been observed in many crystals. In this paper, we will emphatically introduce the progress in optoelectronic functional organic crystals and some correlative principle.

Underwater glider is a new type of autonomous underwater vehicle driven by gravity. In order to study the relationship between the motion parameters and control variable of the underwater glider, solve the fluctuation problem of pitching angle and attack angle in the process of attitude changing, simulation via the software Mat lab is performed based on the kinematic equations of underwater glider in vertical plane. The results show that the longer the cycle of bary center adjusting, the smaller the fluctuating extent of the pitching angle. It seems that this fluctuation of underwater glider is not affected by the variation of buoyancy adjusting, and the fluctuation of attack angle may be affected by the time center location difference between these two adjusting cycles.

Underwater glider, as a combination product of buoy technology and underwater vehicle, has broad application prospect in marine scientific research, environmental monitoring, resource exploration and military reconnaissance etc, because of the advantages of low-noise, long range, long duration and cost-efficiency. The conceptual design, body construction design based on modularization integrative 2-DOF attitude adjustment mechanism design and buoyancy adjustment system design based on accurate measurement are introduced. Then the design of the low power control system for underwater glider is described in detail.

In the Orientalist discourse, the Orient was backward and silent and was deprived of right to have their voice heard. However, in The Hundred Secret Senses, the author Amy Tan, the famous contemporary Chinese American writer, deconstructed Orientalist discourse by using some narrative strategies: talk-story and double first-person limited point of view.

Analyses the factors in Taiwanese credit card fraud, and gives case studies in order to classify the main types of fraud; these include fraudulent use of other people’s cards, credit card applications with forged documents, use of credit cards for illicit financing, looking for authorisation loopholes to conduct scams, and frauds committed by the staff at financial institutions. Outlines the government’s solutions to the problem, including anti‐counterfeit designs, legal tasks, fraud prevention mechanisms, establishing risk systems, management of merchants, and educational promotional activities. Concludes with recommendations for further action by government agencies, credit card companies, privileged stores, and cardholders.

Discusses the history, content and shortcomings of the 2003 Money Laundering Control Act of Taiwan, with two case studies involving money laundering (by the Yeh brother and Mr Chen, and by Mr Tzeng). Begins with the history of money laundering since Taiwan opened its financial markets in 1980, culminating in the 1996 Money Laundering Control Act, which was the first specific legislation of its type ever enacted by an Asian country. Details the provisions of the 2003 Act, including the requirements for financial institutions to ascertain clients’ identities and to establish systems for detecting suspect financial transactions and preventing money laundering. Shows how the Money Laundering Prevention Center is enforcing the Act, how international cooperation is allowed for, and how institutions must operate Know Your Customer and Know Your Employee schemes. Indicates the need for still better regulations, and for improved training of financial institution employees so that the regulations can be effectively implemented.