302 results on '"M. Ono"'
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2. 28-GHz ECHCD system with beam focusing launcher on the QUEST spherical tokamak
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Atsushi Fukuyama, Shin Kubo, Takahiro Nagata, Yuichi Takase, M. Sakaguchi, Hiroshi Idei, K. Mishra, Makoto Hasegawa, Akira Ejiri, Masaharu Fukuyama, M. Ono, Yoshihiko Nagashima, Satoru Kobayashi, A. Higashijima, Toru Ii Tsujimura, Shinichiro Kojima, Katsumasa Nakamura, Osamu Watanabe, Tsuyoshi Imai, Kengoh Kuroda, Naoki Matsumoto, Tsuyoshi Kariya, S. Shimabukoro, Takumi Onchi, Kazuaki Hanada, Miu Yunoki, and Sadayoshi Murakami
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Physics ,business.industry ,Mechanical Engineering ,Launched ,Beam steering ,Plasma ,Polarizer ,Spherical tokamak ,Polarization (waves) ,01 natural sciences ,010305 fluids & plasmas ,law.invention ,Optics ,Nuclear Energy and Engineering ,law ,0103 physical sciences ,Incident beam ,Physics::Accelerator Physics ,General Materials Science ,010306 general physics ,business ,Civil and Structural Engineering - Abstract
New polarizer and launcher systems on a 28-GHz electron-cyclotron (EC) heating and current drive (HCD) system have been developed for non-inductive second-harmonic EC-plasma-current ramp-up in the QUEST spherical tokamak. A launcher system with two quasi-optical mirrors providing beam steering capability was designed to focus the incident beam to a small-sized waist of ∼0.05 m at the second-harmonic EC resonance layer. A relatively large focusing mirror was designed based on a Kirchhoff integral code developed to derive wave solutions. The focusing property of the launched beam was first confirmed with a 3-dimensional (3D) electromagnetic-wave simulator. Focusing characteristics were also checked at low-power test facilities, together with the steering capability. The performance of this launcher system was demonstrated to work as designed, and assembled in the QUEST device. The system was applied to the non-inductive second-harmonic EC plasma ramp-up experiments with no optimization required regarding the incident polarization. The results obtained for the non-inductive plasma ramp-up are also presented.
- Published
- 2019
3. Impact of common cardio-metabolic risk factors on fatal and non-fatal cardiovascular disease in Latin America and the Caribbean: an individual-level pooled analysis of 31 cohort studies
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José Boggia, Alvaro Cc Maciel, Pablo Perel, Marselle B Amadio, Flávio Danni Fuchs, Jorge Tartaglione, Carla Do Bernardo, João Luiz Bastos, Jorge Salmerón, Claudia Bambs, Karen Oppermann, Gilbert Brenes-Camacho, J. Jaime Miranda, Poli Mara Spritzer, Nohora I Rodriguez, Oscar Muñoz, Pollyanna Kássia de Oliveira Borges, Edward W. Gregg, Laura Gutierrez, Ramon A Sanchez, Walter G Espeche, Paula Ramírez-Palacios, Rodrigo M. Carrillo-Larco, Juan E. Blümel, Nelson A S Silva, Marco Aurélio Peres, Leila Beltrami Moreira, Martin Lajous, Clicerio González-Villalpando, Eleonora d'Orsi, Karina Mary de Paiva, Sérgio Viana Peixoto, Alexandre C. Pereira, Majid Ezzati, Betty S Manrique-Espinoza, Miguel Bravo, Ramón Álvarez-Vaz, Maria S. Castillo Rascon, Suely Ga Gimeno, Luis Rosero-Bixby, Rosalba Rojas-Martínez, Elard Koch, Ricardo Oliveira Guerra, Dalia Stern, Anselm Hennis, Vilma Irazola, Aaron Salinas-Rodriguez, Catterina Ferreccio, Carlos A. Aguilar-Salinas, Paulo A. Lotufo, Blanca H. Ceballos, Goodarz Danaei, Cassiano Ricardo Rech, Donaji Gomez-Velasco, Adrian Cortes-Valencia, Thiago L N Silva, Andrea R. V. R. Horimoto, Adolfo Rubinstein, Mariachiara Di Cesare, Cecilia Baccino, Roberto de Sa Cunha, Liam Smeeth, Verônica Colpani, Sandra C. Fuchs, Maria Fernanda Lima-Costa, Larissa Pruner Marques, Ruy Lopez-Ridaura, Gonzalo Grazioli, Horacio A Carbajal, Andrea Huidobro, Sandra Cortés, Karen Glazer Peres, Berenice Rivera-Paredez, Antonio Bernabe-Ortiz, Martin R Salazar, Álvaro Ruiz-Morales, José Geraldo Mill, Ian Hambleton, María-Elena González-Villalpando, Gloria L. Beckles, William H. Dow, Fiorella Tartaglione, David Alejandro González-Chica, Jackie A. Cooper, Rafael Velázquez-Cruz, Katia Vergetti Bloch, Lariane M Ono, Fernando Luiz Herkenhoff, and Wellcome Trust
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business.industry ,Regression dilution ,Disease ,Blood pressure ,Relative risk ,Medicine ,Public aspects of medicine ,RA1-1270 ,Risk factor ,business ,Body mass index ,Disease burden ,Cohort study ,Demography ,Research Paper - Abstract
Background: Estimates of the burden of cardio-metabolic risk factors in Latin America and the Caribbean (LAC) rely on relative risks (RRs) from non-LAC countries. Whether these RRs apply to LAC remains unknown. Methods: We pooled LAC cohorts. We estimated RRs per unit of exposure to body mass index (BMI), systolic blood pressure (SBP), fasting plasma glucose (FPG), total cholesterol (TC) and non-HDL cholesterol on fatal (31 cohorts, n=168,287) and non-fatal (13 cohorts, n=27,554) cardiovascular diseases, adjusting for regression dilution bias. We used these RRs and national data on mean risk factor levels to estimate the number of cardiovascular deaths attributable to non-optimal levels of each risk factor. Results: Our RRs for SBP, FPG and TC were like those observed in cohorts conducted in high-income countries; however, for BMI, our RRs were consistently smaller in people below 75 years of age. Across risk factors, we observed smaller RRs among older ages. Non-optimal SBP was responsible for the largest number of attributable cardiovascular deaths ranging from 38 per 100,000 women and 54 men in Peru, to 261 (Dominica, women) and 282 (Guyana, men). For non-HDL cholesterol, the lowest attributable rate was for women in Peru (21) and men in Guatemala (25), and the largest in men (158) and women (142) from Guyana. Interpretation: RRs for BMI from studies conducted in high-income countries may overestimate disease burden metrics in LAC; conversely, RRs for SBP, FPG and TC from LAC cohorts are similar to those estimated from cohorts in high-income countries. Funding: Wellcome Trust (214185/Z/18/Z)
- Published
- 2021
4. Author response: Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
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Zahra Mohammadi, Abdul Basit, Helena I. S. Nogueira, Soile E. Puhakka, Hongsheng Bi, Ari Voutilainen, Davood Khalili, Bin Zhou, Dermot O'Reilly, Natascia Rinaldo, Paulo A. Lotufo, Bahareh Kheiri, Thein Thein Htay, Simona Giampaoli, Goodarz Danaei, M. Fernanda Lima-Costa, Simona Bo, Peter Schnohr, Jerzy Chudek, Francesco Panza, Ling Yang, Katia Vergetti Bloch, Vincenzo Capuano, Holly E. Syddall, Dong Zhao, Indah Suci Widyahening, Maria Lorenza Muiesan, Leng Huat Foo, Mohsen Azimi-Nezhad, Merete Osler, Laura Torres-Collado, Manu Raj, Adroaldo Cesar Araujo Gaya, Susi Kriemler, Ali Akbar Shayesteh, Aneta Grajda, Anette Varbo, Kazem Mohammad, Leila Beltrami Moreira, Shu Ti Chiou, Iuliia A Rusakova, Jyh Eiin Wong, Torben Jørgensen, Lela Sturua, Lubica Ticha, Hamid Hakimi, Hazzaa M. Al-Hazzaa, Yanina Zócalo, Freda Pitakaka, Savvas C. Savva, Rajeev Gupta, Jennifer Servais, Marie Kunešová, Johanna M. Geleijnse, Elysée Claude Bika Lele, Yannis Manios, Jorge Escobedo-de la Peña, Yufang Bi, Chinh Nguyen Huu, Sibel Gogen, Viviane Cunha Cardoso, Kristine H. Allin, Ana Azevedo, Line Tang Møllehave, Vincent Jr DeGennaro, Novie O. Younger-Coleman, Gretchen A Stevens, Dickman Gareta, Holger Theobald, Anja Schienkiewitz, Bekbolat Zholdin, Janice Luisa Lukrafka, Adela Chirita-Emandi, Ulla Roggenbuck, Kenisha Russell Jonsson, Robespierre Ribeiro, Gabriele Eiben, Eero Kajantie, Sounnia Mediene Benchekor, Fariborz Mansour-Ghanaei, Mary Simon, Prakash C. Gupta, Mohammad Esmaeel Motlagh, Emanuela Gualdi-Russo, María Elena Díaz-Sánchez, Pilar Guallar-Castillón, Bee Koon Poh, Cristina Padez, Azaliia M Tuliakova, Sarah P. Garnett, William R. Tebar, Yingfeng Zheng, Suhad Bahijri, Christina Mavrogianni, Mihaela Vladulescu, Jan A. Staessen, Paula Duarte de Oliveira, Rui Ornelas, Michael Sjöström, Charles Agyemang, Slawomir Koziel, Shohreh Naderimagham, Jari Jokelainen, Stephen T. McGarvey, Patrick Pasquet, Farnam Mohebi, Nader Saki, Aida Pilav, Azim Nejatizadeh, Marianna Noale, Habiba Ben Romdhane, Luís B. Sardinha, Laura Lauria, Jun Hata, Kodanda R Kanala, Gert B. M. Mensink, Nils Lehmann, Elio Riboli, Carolina Tarqui-Mamani, Rodrigo M. Carrillo-Larco, Rosangela Fernandes Lucena Batista, Victoria E Soto-Rojas, Luis Serra-Majem, Martina Müller-Nurasyid, Felipe Vogt Cureau, Lekhraj Rampal, Zhamilya Battakova, Ludmila Sevcikova, Suhaila Abdul Ghaffar, Fikru Tullu, Aung Soe Htet, Angel R. Gonzalez, Annette J. Dobson, Kavumpurathu Raman Thankappan, Hélène Delisle, Francisco J. Félix-Redondo, Ramón Suárez-Medina, Annika Rosengren, Sania Nishtar, Tanja G. M. Vrijkotte, Wolfgang Ahrens, Osvaldo Santos, Maria Cecília Formoso Assunção, Kazi M. Jamil, Stefano Marventano, Wenbin Wei, Norsyamlina Che Abdul Rahim, Shukri F. Mohamed, Bente Sparboe-Nilsen, Soon-Woo Park, Ana Isabel Rito, David Goltzman, W. M. Monique Verschuren, Catterina Ferreccio, Marta Buoncristiano, Ramón Alberto Rascón-Pacheco, Pradeep Joshi, Edward D Janus, Laetitia Huiart, Ala'a Alkerwi, Lorenza Pilotto, Mohannad Al Nsour, Daan Kromhout, Marius B. Bjertness, Oanh T. H. Trinh, Nico Dragano, Angélica Ochoa-Avilés, Ingunn Holden Bergh, Yuki Fujita, Juraci Almeida Cesar, Hajer Aounallah-Skhiri, Maria Dorobantu, Jordi Sunyer, Wolfgang Kratzer, Susanne R. de Rooij, Drude Molbo, Rebecca Goldsmith, Jean Woo, Mohammad El-khateeb, Tiffany K. Gill, Nish Chaturvedi, Benjamin Acosta-Cazares, Erik Lykke Mortensen, Nikhil D. Patel, Francesco Pistelli, Yuan He, Ivana Radic, Yi Zeng, Ilse Khouw, Reynaldo Martorell, Ching-Yu Cheng, Stine Schramm, Hana Shimizu-Furusawa, Jacek Jóźwiak, Radwan Qasrawi, Isti Ilmiati Fujiati, Charles Sossa Jérome, Ben Schöttker, Mikhail Benet, Anastasia Markaki, Christopher T. Cowell, Bharathi Viswanathan, Renata Kuciene, Jose Eugenio Lozano, Pedro J Ortiz, Delphine De Smedt, Elaine M. Murtagh, Kamel Ajlouni, Carlos A. Aguilar-Salinas, Graziella D'Arrigo, Xiangjun Wang, Lars Lind, Macia Enguerran, Marjeta Mišigoj-Duraković, Bo Werner, Jean-Michel Gaspoz, Kyungwon Oh, Seyed Rasoul Zakavi, Daniel Fernández-Bergés, Felix Kaducu, Ramon O. Jimenez, Jonathan E. Shaw, Nipa Rojroongwasinkul, Aicha Soumare, Astrid Petersmann, Tomasz Grodzicki, Parvina Mukhtorova, Eha Nurk, Bhawesh Koirala, Óscar Lopes, Ana Jelakovic, Karolina Milkowska, Magda Gasull, Regina Heidinger-Felso, Marcela González-Gross, Belong Cho, Daphne Mirkopoulou, Salvador Villalpando, Tran Quoc Bao, José Boggia, Daniela Galeone, Josep Redon, Matthias Bopp, Abbas Rezaianzadeh, Dusko Bjelica, Amir Houshang Mehrparvar, Felipe F. Casanueva, Khairil Si-Ramlee, Soheir H Ahmed, Maria Nordendahl, Luciana Zaccagni, Mahboubeh Parsaeian, Rod Jackson, Jorge Motta, Keiu Nelis, Fernando Rigo, Andrzej Pajak, Christa Meisinger, Clara Homs, Namuna Shrestha, Mar Alvarez-Pedrerol, Xun Tang, Johann Willeit, Motahareh Kheradmand, Jean Dallongeville, Jean-Bernard Ruidavets, Anne Tjønneland, Diana A. Santos, Lynne M. Boddy, Jie Hao, David Alejandro González-Chica, Elin Kolle, Jingli Gao, Małgorzata Mossakowska, Isabel O. Oliveira, Giuseppe Grosso, Seongjun Ha, Olfa Saidi, Albina A Fakhretdinova, Oye Gureje, Raluca Pop, Iulia Jurca Simina, Nuno Lunet, Maria Forsner, Peter Bjerregaard, Rachael McLean, Antonio Cabrera de León, Guy De Backer, José A. Casajús, Guang Ning, Emmanuella Magriplis, Laura Censi, Graziella Bruno, Valentina Peterkova, Angelique Chan, Yvonne T. van der Schouw, Charalambos Hadjigeorgiou, Anjani Kumar Jha, Toomas Veidebaum, Thamara Hubler Figueiró, Jana Kratenova, Michelle Cilia, Ivo Rakovac, Bill Stavreski, Ya Xing Wang, Oscar Noboa, Romana Roccaldo, Sara Magnacca, Johan Sundström, Peter Stehle, Tania Lopez, Francis Delpeuch, Julianne Williams, Ellisiv B. Mathiesen, Leanne M. Riley, Claudia M. Hormiga, Joanne Katz, Ekaterina Stoyanova, Heloisa Bettiol, Gabriele Nagel, Alireza Khosravi, Lars Bo Andersen, João Breda, Jørgen Meisfjord, Ahmad Faudzi Yusoff, Marjeta Majer, Robert Beaglehole, Caleb Ochimana, Shynar Abdrakhmanova, George S. Stergiou, Blanca Sandra Ruiz-Betancourt, Leon A. Simons, Eng Joo Tan, Victoria Farrugia Sant'Angelo, Gry Skodje, Maryam Keramati, Liv Elin Torheim, Seppo Koskinen, Assembekov Batyrbek, Jaakko Tuomilehto, Marjo-Riitta Järvelin, Ming-Hui Zhao, Krista Fischer, Tobias F. Rinke de Wit, Agnès Le Port, Reza Homayounfar, James E. Bennett, Yuna He, Matsuda Fumihiko, Qi Sheng You, Angela Spinelli, Scott B. McLean, Shirin Djalalinia, Thet Thet Mu, Yves Martin-Prével, Rafael N. Pichardo, Gailute Bernotiene, Pietro Amedeo Modesti, Frederick C. W. Wu, Chandini Nekkantti, Daniela Rodrigues, Tandi E. Matsha, Mihai Gafencu, Xingwang Ye, Salar Rahimikazerooni, Trevor S. Ferguson, Christophe Tzourio, Marie Zins, Fernando Rodríguez-Artalejo, Xu Ma, Elin Pettersen Sørgjerd, Lourdes Ribas-Barba, Nalan Uysal, Salim Berkinbayev, Enisa Kujundzic, Sari Voutilainen, Iraj Mohebbi, Heiner Boeing, Jorge Mota, Jana Námešná, Maria Tsigga, Zivka Dika, Gulmira Aitmurzaeva, Xu Lin, Valéria Regecová, Herman Schargrodsky, Stevo Popovic, Amelia C. Crampin, Hannu Uusitalo, André Luiz Sena Guimarães, Ali Esmaeili, Catherine Kyobutungi, Virginija Dulskiene, Diego Augusto Santos Silva, David De Ridder, Lizzy M. Brewster, Hashem Jaddou, Eunice Ugel, José Camolas, Azli Baharudin, Idris Guessous, Sok King Ong, Tabara Yasuharu, Ali Ghanbari, Anne W. Taylor, Iraj Nabipour, Justyna Godos, Cyrus Cooper, Bruna Gonçalves Cordeiro da Silva, Gonzalo Valdivia, Gyulli M. Kazakbaeva, Takuro Furusawa, Pawel Kurjata, Diego Vanuzzo, Marvin Cervantes-Loaiza, Karen Morgan, Mostafa Qorbani, Rute Santos, Marika Ferrari, Diego Salmerón, Ida Maria Schmidt, Gao Pei, Abu Am Hanif, Balkish M. Naidu, Maria Wany Louzada Strufaldi, Moesijanti Soekatri, Marcia Scazufca, Katharina Maruszczak, Jacqueline Ramke, Elvis Oa Wambiya, Kairit Mikkel, Napoleón Pérez-Farinós, Natalia Nowak-Szczepanska, Miao Li Chee, Jose Sanchez-Abanto, Rajaa Al-Raddadi, Michel Joffres, Vayia Rarra, Ningli Wang, Charmaine A. Duante, Sheikh Mohammed Shariful Islam, Manoli Garcia-de-la-Hera, Weili Yan, Dong Wook Shin, Rômulo Araújo Fernandes, Ilona Nenko, Sanjib Kumar Sharma, Alfonso Siani, Indrapal I. Meshram, Imelda A. Agdeppa, Ei Ei K. Nang, Ian Rouse, Avula Laxmaiah, Ana M. B. Menezes, Yih Chung Tham, Ebrahim Eftekhar, María José Tormo, Felicia Cañete, Marie Eliasen, Lutgart Braeckman, Dirk Vanderschueren, Genc Burazeri, Kari Kuulasmaa, Jesús Vioque, Marisa K. Sophiea, Agneta Sjöberg, Katarzyna Dereń, Albertino Damasceno, Jochanan Stessman, Stig E. Bojesen, Aline Meirhaeghe, Else Karin Grøholt, Flávio Danni Fuchs, Robert Lundqvist, Frédéric Gottrand, Jeongseon Kim, Helmut Schröder, Joanna Baran, Karina Mary de Paiva, Yousef Khader, Eric Monterrubio-Flores, Aneta Weres, Hans Concin, Damaskini Valvi, Sari Hantunen, Machi Suka, Elena Sacchini, Norbert Amougou, Ursula Kiechl-Kohlendorfer, Edwige Landais, Viktoria Anna Kovacs, Rosemarie Martin, Kenneth James, Amaneh Shayanrad, Grethe S. Tell, Norazizah Ibrahim Wong, Vedrana Sember, Anelise Reis Gaya, Konrad Jamrozik, Thorkild I. A. Sørensen, Martin Neovius, Urho M. Kujala, Nathalie Michels, Marcel Goldberg, Alexandra Cucu, Liliana Dacica, Adelheid Weber, Hermann Pohlabeln, Sandjaja, Jukka T. Salonen, Patricia Varona-Pérez, Tiina Laatikainen, Jolanta Słowikowska-Hilczer, Ana Paula Carlos Cândido, Julie Taylor, Anabela Mota-Pinto, Cora L. Craig, Teresa Shamah-Levy, María Dolores Chirlaque, Mohd Azahadi Omar, Dominique Cottel, Charumathi Sabanayagam, Andrea Gazzinelli, Mieczysław Litwin, Sadaf G. Sepanlou, Adolfo Rubinstein, Abbas Dehghan, Rildo de Souza Wanderley Júnior, Wenhua Zhao, Aleksandra Piwońska, Yong Tao, Bontha V. Babu, Marc J. Gunter, Harunobu Nakamura, Wojciech Drygas, Eiji Oda, Jia Li Duan, Stefan Söderberg, Anthony Kafatos, Lynell V Maniego, Els Clays, Wei-Yen Lim, Marshall K. Tulloch-Reid, Mariachiara Di Cesare, Mattias Johansson, Simona Costanzo, Margot González-León, Matthias Nauck, Henry Völzke, George Luiz Lins Machado-Coelho, Annette Peters, Rajiv T Erasmus, Juan Francisco Miquel, Andrea Gualtieri, Abdul Hamid Zargar, Kaare Christensen, Peter Willeit, Tanja Stocks, Christine Cameron, Samuel C. Dumith, Janina Petkeviciene, Boyd Swinburn, Magdalena Muc, Sabine Schipf, Tajana Zeljkovic Vrkic, Martin Bobak, Damian K Francis, Veronica Mocanu, Karien Stronks, Antonisamy Belavendra, Artur Mazur, Nagalla Balakrishna, Jardena J. Puder, Mehrdad Azmin, Shelly R. McFarlane, Sara Santos Sanz, Yang Yang, Anneke Blokstra, Rafel Ramos, Ertugrul Celikcan, Jody C Miller, Jesús Ibarluzea, Svetlana A. Shalnova, Maria Elisa Zapata, Guansheng Ma, Fereidoun Azizi, Beatriz D'Agord Schaan, Pedro Marques-Vidal, William A. Neal, Ana B. Crujeiras, Zhenyu Zhang, Naser Ahmadi, Abdullatif Husseini, Alun Evans, Jiang He, Edyta Łuszczki, Maria G. Stathopoulou, Alibek Mereke, Mari-Liis Tammesoo, Axel C. Carlsson, Helen Gonçalves, Idowu O Senbanjo, Jim Mann, Rajendra Pradeepa, Juel Jarani, Eva Martos, Eugene Sobngwi, Themistoklis Tzotzas, Vassilis Zafiropulos, Reina Engle-Stone, Atul Trivedi, Hui Cai, Sarah Filippi, Georg Posch, Galina Obreja, Cecily Kelleher, Sareh Eghtesad, Chung T Nguyen, Kay-Tee Khaw, Joseph Cacciottolo, Ana Henriques, Yi-Ting Lin, Anil Poudyal, Liam Smeeth, Kenji Shibuya, Emma Ruiz Moreno, Annamari Lundqvist, Thor Aspelund, Caroline H.D. Fall, Philippe Amouyel, Kristyna Zejglicova, Argyro Karakosta, Piotr Bandosz, Juvenal Soares Dias-da-Costa, Maria Lazo-Porras, Maung Maung Than Htike, Dalia Luksiene, Jutta Stieber, Augusto Di Castelnuovo, Aryeh D. Stein, Lechaba Tshepo, Judith Benedics, Aletta E. Schutte, Jürgen König, Magdalena Korzycka, Grzegorz Sobek, Dimitrios Trichopoulos, Tai Hing Lam, Yn-Tz Sung, Masanori Iwasaki, Elias F. Gudmundsson, Antonio Mistretta, Daniel Lemogoum, Nimmathota Arlappa, Isabelle Herter-Aeberli, Khanh Le Nguyen Bao, Shoichiro Tsugane, Kaosar Afsana, Alireza Sadjadi, Myriam Galfo, Jean Claude Mbanya, Bernardo L. Horta, Marleen E. Hendriks, M. Arfan Ikram, Fadia AlBuhairan, Huashuai Chen, Marzieh Katibeh, Sidsel Graff-Iversen, Sahar Saeedi Moghaddam, Larissa Pruner Marques, Louise Eriksen, Aleksandra Gomula, Ricky Eddie, Maciej Banach, Jost B. Jonas, Andrea R. V. R. Horimoto, Slavica Sović, Charles Mondo, Felix Gutzwiller, Mariana Sbaraini, Aye Aye Sein, Henrike Galenkamp, Jaume Marrugat, Nazan Yardim, Cecilia Björkelund, Luigi Palmieri, Roya Kelishadi, Jie Mi, Nahla Hwalla, Jing Liu, Davide Noto, Panayiotis K. Yiallouros, Kelias P. Msyamboza, Judith Simons, Sofia Malyutina, Michele Monroy-Valle, Andres Metspalu, Lariane M Ono, Rafaela Rosário, Flora A. Ukoli, Efthymios Kapantais, Enzo Manzato, S. Goya Wannamethee, Alison J Price, Gregorio Varela-Moreiras, Ali Reza Safarpour, Erfan Ghasemi, Janine Clarke, René Charles Sylva, Wan Nazaimoon Wan Mohamud, Zhamyila Usupova, Chaoqiang Jiang, Julio Zuñiga Cisneros, Freja B Kampmann, Wei Cheng Lo, Reza Mohammadpourhodki, Kaspar Staub, Mojtaba Farjam, Vincenzo Solfrizzi, Garry L. Jennings, Fabio Galvano, Monika Zuziak, Karin De Ridder, Lucie Viet, Anna Bugge, Mehdi Yaseri, Safiah Md Yusof, Sandra C. Fuchs, Emmanuel Cohen, Snehalatha Chamukuttan, Maria Ruiz-Castell, Karen Sparrenberger, Pedro Plans-Rubio, Wei Zheng, Eldridge Ferrer, Martijn Huisman, Maria Hassapidou, Iris Pigeot, Jakub Stokwiszewski, Domenico Palli, Ewelina Czenczek-Lewandowska, Ramiro Guerrero, Farzad Hadaegh, Han Cg Kemper, Saeid Safiri, Ivan Pećin, Arnaud Chiolero, Niels Møller, Jorge Bezerra, Ulrike Gehring, Iná S. Santos, Dénes Molnár, Muhammad Fadhli Mohd Yusoff, Marie Moitry, Nizal Sarrafzadegan, Jacqueline F. Price, Ranko Stevanovic, Sai Yin Ho, Georg Lappas, Alberto Palloni, Malay K. Mridha, Elaine M. Dennison, Jeonghee Lee, Saeid Eslami, Rahman Shiri, Japhet Killewo, Juergen Breckenkamp, Mathilde Kersting, Y Nikitin, Iqbal Bata, Geetha R Menon, Maria Avdicova, Sanjay Rampal, Antônio Augusto Moura da Silva, Kirsten Mehlig, Chien-An Sun, Ramin Heshmat, Violeta Iotova, Stefaan Demarest, Mette Rasmussen, Dirk De Bacquer, San-Lin You, Suzanne N Morin, Martin Gulliford, Maties Torrent, Luc Dauchet, Fred Paccaud, Paibul Suriyawongpaisal, Sherali Rakhmatulloev, Hyeon Chang Kim, Markku Peltonen, Ruth Frikke-Schmidt, Vera Musil, Ahmad Ali Zainuddin, Angela Chetrit, Dan Zhu, Gowri Mahasampath, Ulrich Keil, Sérgio Viana Peixoto, Haiquan Xu, Helle-Mai Loit, Valérie Deschamps, Ilpo Huhtaniemi, Lijuan Liu, Marialaura Bonaccio, Altan Onat, Rody G. Sy, José María Huerta, Ko Ko Zaw, Akihiro Yoshihara, Peter Ueda, Belgin Ünal, Rachel Dankner, Andrzej Wiecek, Eman Aly, Ruzena Kubinova, Justina Vaitkeviciute, Hanna Tolonen, Priscilla Duboz, Orn Olafsson, Yin Guo, Chiara Donfrancesco, Salim Mohanna, Dusan Grafnetter, Daniel Weghuber, Ali Ahmadi, Rosemary B. Duda, E. Shyong Tai, Louise A. Baur, Nihal Thomas, Prabhdeep Kaur, Norlaila Mustafa, Shariq Rashid Masoodi, Liis Nelis, Badreya Al-Lahou, J. Jaime Miranda, Lèlita Santos, Aroor Bhagyalaxmi, Mohamed Bamoshmoosh, Børge G. Nordestgaard, Jeannette Lee, Ahmad Reza Dorosty, Alain Morejon, Ying-Wei Wang, Jakob Tarp, Rosalba Rojas-Martínez, Luxia Zhang, Bahram Mohajer, Maja Bæksgaard Jørgensen, Jurate Klumbiene, Zhengming Chen, Ambady Ramachandran, Andrea Rodriguez-Martinez, Alisha N. Wade, Suyeon Park, Janne Schurmann Tolstrup, Lucjan Szponar, Krishna Kumar Aryal, Tahir Aris, Mahfuzar Rahman, Dorja Vočanec, Juan P. González-Rivas, Rob M. van Dam, Daniel Bia, Oonagh Markey, Ryutaro Ohtsuka, Kumiko Ohara, Ričardas Radišauskas, Jurate Medzioniene, Tiina Vlasoff, Tania Tello, Suzanne C. Ho, Kodavanti Mallikharjuna Rao, May Soe Aung, Vesselka Duleva, Michael Hobbs, Lutgarde Thijs, Marjolein Visser, Parasmani Dasgupta, Inge Huybrechts, Raimund Erbel, Alice Bonilla-Vargas, Hermann Brenner, Mohammad Reza Fattahi, Jolanda Hyska, Roman Topor-Madry, Ranjit Mohan Anjana, Merike Liivak, Eruke E. Egbagbe, Mathilde Savy, Herculina S. Kruger, Neil Murphy, Vinay Nangia, Cesar G. Victora, Mostafa K. Mohamed, H. Bas Bueno-de-Mesquita, Gabriella Gruden, Marcos André Moura-dos-Santos, Mohammed Rasoul Tarawneh, Maria Teresa Menzano, Francesco Branca, Abdonas Tamosiunas, Elena Bogova, Niveen M E Abu-Rmeileh, Maroje Sorić, Aleksander Giwercman, Elżbieta Dziankowska-Zaborszczyk, Tatjana Hejgaard, Yves Kameli, Margarita Samoutian, Andreia N. Pizarro, Jin Soo Moon, Frank Claessens, Zulfiqar A Bhutta, Frank Tanser, Nor Azwany Yaacob, Vanina Bongard, Gregor Jurak, Johan G. Eriksson, Christina-Paulina Lambrinou, Hanspeter Stamm, Kim Overvad, Yanping Li, Carsten Oliver Schmidt, Thomas Meinertz Dantoft, Wichai Aekplakorn, Anwar Batieha, Eduardo Capuano, Teresa Haugsgjerd, Jeremy M. Jacobs, Paola Russo, Nguyen D Nguyen, Luis Revilla, Hossein Poustchi, Farid Najafi, Giovanni de Gaetano, Wan Mohamad Wan Bebakar, Paul Elliott, Denise Eldemire-Shearer, Angela Döring, Giovanni Viegi, Xiaoguang Yang, María-Elena González-Villalpando, Maria Puiu, Maria Benedetta Donati, Andrew Wong, Tomasz Zdrojewski, Carlos P. Boissonnet, Mohamad Hasnan Ahmad, Mahmudur Rahman, Günther Fink, Marcia Makdisse, Dragana P Jovic, Aline Wagner, Coimbatore Subramaniam Shanthirani, Pascal Bovet, Dong Wook Kim, Tom Wilsgaard, Anders Grøntved, Thirunavukkarasu Sathish, Antonia Trichopoulou, Noushin Mohammadifard, Igor Spiroski, Natasja M. van Schoor, Cláudia S. Minderico, Betina H. Thuesen, Queenie Chan, Ulf Ekelund, Laura A. Rodríguez-Villamizar, Line Lund Kårhus, Cihangir Erem, Amina Barkat, Maria Paula Santos, Fernanda Cunha Soares, Constanta Huidumac Petrescu, Allan G. Hill, Honor Bixby, Benoît Salanave, Joana Carvalho, Maigeng Zhou, Ofra Kalter-Leibovici, Roy A Wong-McClure, Kim F. Michaelsen, Doris Stöckl, Rosalynn Siantar, Jouko Saramies, José R. Banegas, Quang Ngoc La, Uruwan Yamborisut, Parinaz Mehdipour, Farhad Pourfarzi, Sudha Ramachandra Rao, Katsuyasu Kouda, Chien-Jen Chen, Rafael dos Santos Henrique, Martin Nankap, Allan Linneberg, Ronald D. Gregor, Rudolf Kaaks, Maria do Carmo Franco, Marta García-Solano, Beata Gurzkowska, Bahman Cheraghian, Stefaan De Henauw, Daniel Ferrante, Johanna A. Otero, Jamila Abubakar Garba, Antonio Pedro Graça, Sumit Bharadwaj, Shiqi Zhen, Xiu-Hua Guo, Prashant Mathur, Raphael Mendes Ritti-Dias, Kouamelan Doua, Esteban Carmuega, Majid Shirani, Przemyslaw Slusarczyk, Petra Rust, Visnja Djordjic, Farahnaz Joukar, Johanna Gunnlaugsdottir, Leila Houti, Nayu Ikeda, Imperia Brajkovich, Amirabbas Momenan, Erik J. Timmermans, Marcin Rutkowski, Biruta Velika, Joana Araújo, Jostein Steene-Johannessen, Christa L. Lilly, Per Tynelius, Michael Tornaritis, Anne Juolevi, Fatima Zahra Laamiri, Carl Lachat, Kai-Uwe Saum, Espen Bjertness, Ana P. Ortiz, Joel G. R. Roy, Himanshu K. Chaturvedi, Michelle Holdsworth, Niels Wedderkopp, Johan Van der Heyden, Mukharram M. Bikbov, Hsien-Ho Lin, Eva Corpeleijn, Harshpal Singh Sachdev, Mohammad Reza Mirjalili, Maria del Cristo Rodriguez-Perez, Michala Lustigová, Tuyen D Le, Teresa Norat, Hana Zamrazilová, Garry Brian, Tien Yin Wong, Rosa Haghshenas, Clive Osmond, Diego Giulliano Destro Christofaro, Mahmood Moosazadeh, Vilma Irazola, Olli T. Raitakari, Marco Aurélio Peres, Terho Lehtimäki, Shuohua Chen, Dimitrios Papandreou, Robert J. Adams, Sigmund A. Anderssen, Peter T. Katzmarzyk, Luisa M Macieira, Félicité Tchibindat, Lital Keinan Boker, Toshiharu Ninomiya, Morten Sodemann, Jytte Halkjær, Zbigniew Kułaga, Sophie Visvikis-Siest, Farshad Farzadfar, N Capkova, Zumin Shi, Maria Turley, Zbigniew Gaciong, Giovanni Veronesi, Martin McKee, Veikko Salomaa, Gilad Twig, Elisabetta L. Romeo, Peter Kristensen, Grazyna Jasienska, Victor Guillermo Sequera, Mario V. Capanzana, Con Burns, Emanuela Pettenuzzo, Ming-Dong Wang, Jonathan Giovannelli, Stela McLachlan, Ellis Owusu-Dabo, Stefania Toselli, Maria Teresa Anselmo Olinto, Senthil K Vasan, Sara Schramm, Xenophon Theodoridis, Moyses Szklo, Ramfis Nieto-Martínez, Viswanathan Mohan, Guillermo Frontera, Rahul Malhotra, Thomas Ferrao, Dongfeng Gu, Tomas Vega, Hynek Pikhart, Päivi Mäki, Heba Fouad, Vilnis Dzerve, Christina Howitt, Seyed Mohammad Hashemi-Shahri, Jenny M. Kindblom, Marjolijn C. E. Bragt, G. K. Mini, Qian Wang, Liufu Cui, Andrzej Galbarczyk, Sylvain Sebert, Vilmundur Gudnason, Loreto Santa Marina, Kairat Davletov, Afshin Ostovar, Niloofar Peykari, Nicholas J. Wareham, Wilma M. Hopman, Karl-Heinz Jöckel, Jussi Kauhanen, Breige A. McNulty, Alina Kerimkulova, Youcef Laid, Claes Ohlsson, Stefan Kiechl, Alicia Matijasevich, Boban Mugoša, Srinivasan Kannan, Jyrki K. Virtanen, Mohan Deepa, Mangesh S. Pednekar, Shahla AlDhukair, Cynthia M. Pérez, Vera Lanska, Tint Swe Latt, Dominique Hange, João Luiz Bastos, Eliza Markidou Ioannidou, Leticia Hernandez Cadena, Maya Tanrygulyyeva, Reza Malekzadeh, Dimitrios Poulimeneas, Pedro Ordunez, Thomas Waldhör, Ioannis Pagkalos, Carlo M. Barbagallo, Abla M. Sibai, Peter Vollenweider, Asher Fawwad, Emily Sonestedt, Elena Pahomova, Santosh K. Bhargava, Patrick Kolsteren, Aya Mostafa, Fangfang Chen, Flavio Nervi, Imre Janszky, Arvind Pandey, Renata Cifkova, Alexandre C. Pereira, Alejandro Diaz, Alireza Ansari-Moghaddam, Rachakulla Hari Kumar, Jaakko Mursu, Luis A. Moreno, Glen Gironella, Jelena Kos, Tilema Cama, Haakon E. Meyer, Jun Ma, Raphael E. Arku, Ziad Abdeen, Rusidah Selamat, Dianna J. Magliano, Jitendra Jonnagaddala, Konstantinos Gkiouras, Paul Korrovits, Paola Nardone, Paolo Vineis, Kotsedi D Monyeki, Khuong Quynh Long, Alberto Barceló, Camilla T. Damsgaard, Constance Schultsz, Frank J Rühli, Santiago F. Gomez, Tara Coppinger, Muhammad Islam, Pierre Traissac, Eleonora d'Orsi, Irfan Nuhoglu, Rui Providência, Bernard Maire, Leandra Abarca-Gómez, Sinead Brophy, Daniela Pierannunzio, Cristina Taddei, Wen-Harn Pan, Gregor Starc, Abdullah Alkandari, Saeed Dastgiri, Lien Braeckevelt, Gustavo Velasquez-Melendez, Sudhir Kowlessur, Bagher Larijani, Cynthia Robitaille, Mohamed M. Ali, Steiner Krokstad, Noor Ani Ahmad, Anar Dushpanova, Agustinus Soemantri, Susana Sans, Ionela Pascanu, Gwenaëlle Le Coroller, Inger Ariansen, Abhijit Sen, Sergej M. Ostojic, Silvana Donoso, Felix K. Assah, Juan A Rivera, Peter H. Whincup, Oana-Florentina Gheorghe-Fronea, Hanan F. Abdul Rahim, Yadlapalli S. Kusuma, Michael Knoflach, Moein Yoosefi, Cassiano Ricardo Rech, Paul Ferdinand M. Reganit, Tomi-Pekka Tuomainen, Francesco Gianfagna, Stefania Maggi, Mohammad Hossein Somi, Behrooz Hamzeh, Bethlehem D. Solomon, Herman Borghs, Zhanna Kalmatayeva, Heidi Klakk, Akram Pourshams, Naomi S. Levitt, Miquel Porta, Vesna Jureša, Alexander D. Deev, Son Thai Pham, Paula Margozzini, Silvia Bel-Serrat, Dora Romaguera, Monira Alarouj, Winsome R. Parnell, Marloes Cardol, David Faeh, Antonio Bernabe-Ortiz, Giota Touloumi, Maryam Kavousi, Sanja Musić Milanović, Jalila El Ati, Sauli Herrala, Liang Xu, Sirkka Keinänen-Kiukaanniemi, Ian Hambleton, Stefan Savin, Andre Pascal Kengne, R. Krishna Kumar, Kurt Widhalm, Marco M Ferrario, Parisa Amiri, Yi Song, Jianfeng Wu, Jeannette Klimont, Jean Ferrières, Farhad Zamani, Shina Avi, Luis Paulo Gomes Mascarenhas, Aluísio J D Barros, Reecha Sofat, Koen Van Herck, Hoang Van Minh, Enrique Gutiérrez-González, Martine Vrijheid, Susana Cararo Confortin, Antonis Zampelas, Bogdan Wojtyniak, Ausra Petrauskiene, Juha Auvinen, Maryam Sharafkhah, Emanuel Zitt, Majid Ezzati, Young-Ho Khang, Ellina Rakhimova, Magdalena Klimek, Luís Lopes, Erkin M. Mirrakhimov, Maria Lc Iurilli, Günay Can, Mark Woodward, Esther Lopez-Garcia, Mauro Virgílio Gomes de Barros, Ahmed A. Madar, Rainford J. Wilks, Shoaib Afzal, Melanie J. Cowan, Gareth Stratton, Eduardo Salazar Martinez, Sameer Narake, Norie Sawada, Li Juan Wu, Adrian Richter, Licia Iacoviello, Hanno Ulmer, Deepak Amarapurkar, Mohsen Ibrahim, Hamed Pouraram, Massimo Salvetti, Hung-Kwan So, Yonghua Hu, Lars Ängquist, Thi Tuyet-Hanh Tran, Charles Lunogelo, Sabina Zambon, Angelika Schaffrath Rosario, Lauren Lissner, Kamarul Imran Musa, Deepa Weerasekera, Bihungum Bista, Takafumi Ishida, Ekaterina Chikova-Iscener, Mirjam M. Heinen, Tazeen H. Jafar, Semánová Csilla, Raija Korpelainen, Edward W. Gregg, Laura Gutierrez, Victor M. Herrera, Aristides M. Machado-Rodrigues, Fatemeh Malekzadeh, Shouling Wu, Jennifer L. Baker, Clicerio González-Villalpando, Irene G. M. van Valkengoed, Anna Fijałkowska, Meghnath Dhimal, Murat Topbaş, George Moschonis, Robert Eggertsen, Quang Ngoc Nguyen, Janette Walton, Elnaz Faramarzi, Nasheeta Peer, Radka Taxová Braunerová, Harald Geiger, Morteza Shamshirgaran, Lela Shengelia, María Ángeles Dal Re Saavedra, Khem Bahadur Karki, Timothy J. Key, Maria G. Grammatikopoulou, Susana Vale, Bernhard O. Boehm, Songhomitra Panda-Jonas, Iveta Pudule, Elisabete Ramos, Lacramioara Aurelia Brinduse, Paul H. Lee, Terence W O'Neill, Javad Aghazadeh-Attari, Margus Punab, Bojan Jelaković, Eliza Cinteza, Ha Tp Do, and Alison J. Hayes
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education.field_of_study ,business.industry ,Population ,Distribution (economics) ,medicine.disease ,Obesity ,Geography ,medicine ,Underweight ,medicine.symptom ,education ,business ,Body mass index ,Demography - Published
- 2020
5. Trends in cardiometabolic risk factors in the Americas between 1980 and 2014: A pooled analysis of population-based surveys
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J Jaime Miranda, Rodrigo M Carrillo-Larco, Catterina Ferreccio, Ian R Hambleton, Paulo A Lotufo, Ramfis Nieto-MartSínez, Bin Zhou, James Bentham, Honor Bixby, Kaveh Hajifathalian, Yuan Lu, Cristina Taddei, Leandra Abarca-Gómez, Benjamin Acosta-Cazares, Carlos A Aguilar-Salinas, Dolores S Andrade, Maria Cecília F Assunção, Alberto Barceló, Aluisio JD Barros, Mauro VG Barros, Joao Luiz D Bastos, Iqbal Bata, Rosangela L Batista, Mikhail Benet, Antonio Bernabe-Ortiz, Heloísa Bettiol, Daniel Bia, Katia V Bloch, Jose G Boggia, Carlos P Boissonnet, Imperia Brajkovich, Lizzy M Brewster, Christine Cameron, Ana Paula C Cândido, Felicia Cañete, Viviane C Cardoso, Esteban Carmuega, Juraci A Cesar, Queenie Chan, Diego G Christofaro, Janine Clarke, Susana C Confortin, Cora L Craig, Felipe V Cureau, Juvenal Soares Dias-da-Costa, Alejandro Diaz, Silvana C Donoso, Eleonora d'Orsi, Paula Duarte de Oliveira, Samuel C Dumith, Denise Eldemire-Shearer, Paul Elliott, Jorge Escobedo-de la Peña, Trevor S Ferguson, Romulo A Fernandes, Daniel Ferrante, Damian K Francis, Flavio D Fuchs, Sandra C Fuchs, Andrea Gazzinelli, David Goltzman, Helen Gonçalves, Bruna Goncalves Cordeiro da Silva, Angel R Gonzalez, David A Gonzalez-Chica, Margot González-Leon, Juan P González-Rivas, Clicerio González-Villalpando, María-Elena González-Villalpando, Mariano Gorbea Bonet, Ronald D Gregor, Ramiro Guerrero, Andre L Guimaraes, Martin C Gulliford, Laura Gutierrez, Leticia Hernandez Cadena, Victor M Herrera, Wilma M Hopman, Andrea RVR Horimoto, Claudia M Hormiga, Bernardo L Horta, Christina Howitt, Vilma E Irazola, Kenneth James, Ramon O Jimenez, Santa Magaly Jiménez-Acosta, Michel Joffres, Patrick Kolsteren, Orlando Landrove, Maria Lazo-Porras, Christa L Lilly, M Fernanada Lima-Costa, Tania Lopez, George LL Machado-Coelho, Aristides M Machado-Rodrigues, Marcia Makdisse, Paula Margozzini, Larissa Pruner Marques, Reynaldo Martorell, Luis Mascarenhas, Alicia Matijasevich, Anselmo J Mc Donald Posso, Shelly R McFarlane, Scott B McLean, Ana Maria B Menezes, Juan Francisco Miquel, Michele Monroy-Valle, Eric A Monterrubio, Eric Monterubio Flores, Leila B Moreira, Alain Morejon, Suzanne N Morin, Jorge Motta, William A Neal, Flavio Nervi, Ramfis E Nieto-Martínez, Oscar A Noboa, Angélica M Ochoa-Avilés, Maria Teresa Olinto Anselmo, Isabel O Oliveira, Lariane M Ono, Pedro Ordunez, Ana Paula C Ortiz, Pedro J Ortiz, Johanna A Otero, Alberto Palloni, Sergio Viana Peixoto, Alexandre C Pereira, Marco A Peres, Cynthia M Pérez, Rafael N Pichardo, Daniel A Rangel Reina, Ramon A Rascon-Pacheco, Luis Revilla, Robespierre Ribeiro, Raphael M Ritti-Dias, Juan A Rivera, Cynthia Robitaille, Laura A Rodríguez-Villamizar, Rosalba Rojas-Martinez, Joel GR Roy, Adolfo Rubinstein, Blanca Sandra Ruiz-Betancourt, Eduardo Salazar Martinez, Jose Sánchez-Abanto, Ina S Santos, Diego Augusto Santos Silva, Mariana Sbaraini, Marcia Scazufca, Beatriz D Schaan, Herman Schargrodsky, Victor Sequera, Jennifer Servais, Antonio M Silva, Victoria E Soto-Rojas, Karen Sparrenberger, Aryeh D Stein, Ramón Suárez-Medina, Moyses Szklo, William R Tebar, Tania Tello, Marshall K Tulloch-Reid, Peter Ueda, Eunice Ugel, Gonzalo Valdivia, Gustavo Velasquez-Melendez, Roosmarijn Verstraeten, Cesar G Victora, Rildo S Wanderley Jr, Ming-Dong Wang, Rainford J Wilks, Roy A Wong-McClure, Novie O Younger-Coleman, Maria Elisa Zapata, Yanina Zocalo, Julio Zuñiga Cisneros, Goodarz Danaei, Gretchen A Stevens, Leanne M Riley, Majid Ezzati, Mariachiara Di Cesare, Universidad Peruana Cayetano Heredia, Imperial College London, Pontificia Universidad Catolica de Chile, University of the West Indies, Universidade de São Paulo (USP), Miami Veterans Affairs Healthcare System, University of Kent, Cleveland Clinic, Yale University, Caja Costarricense de Seguro Social, Instituto Mexicano Del Seguro Social, Instituto Nacional de Ciencias Medicas y Nutricion, Universidad de Cuenca, Federal University of Pelotas, Pan American Health Organization, University of Pernambuco, Dalhousie University, Federal University of Maranhao, CAFAM University Foundation, University Medical Science, Universidad de la Republica, Centro de Educacion Medica e Investigaciones Clinicas, University of Amsterdam, Canadian Fitness and Lifestyle Research Institute, Universidade Federal de Juiz de Fora, Universidade Estadual Paulista (UNESP), Universidade Federal de Santa Catarina (UFSC), University of Montreal, Universidade Do Vale Do Rio Dos Sinos, National Council of Scientific and Technical Research, Ministry of Health, Instituto Nacional de Salud Publica, Hospital de Clinicas de Porto Alegre, Universidade Federal Do Rio Grande Do sul, McGill University, Andes Clinic of Cardio-Metabolic Studies, Epidemiology and Microbiology, Universidad Icesi, State University of Montes Claros, King's College London, Institute for Clinical Effectiveness and Health Policy, National Institute of Public Health, Universidad Autonoma de Bucaramanga, Kingston General Hospital, Heart Institute, Fundacion Oftalmologica de Santander, Simon Fraser University, Institute of Tropical Medicine, Ministerio de Salud Publica, Harvard TH Chan School of Public Health, West Virginia University, Oswaldo Cruz Foundation Rene Rachou Research Institute, Universidade Federal de Ouro Preto, Hospital Israelita Albert Einstein, Emory University, Gorgas Memorial Institute of Health Studies, Statistics Canada, Gorgas Memorial Institute of Public Health, University of Vale Do Rio Dos Sinos, University of Puerto Rico Medical Sciences Campus, University of Wisconsin-Madison, Minas Gerais State Secretariat for Health, Universidade Nove de Julho, Public Health Agency of Canada, Universidad Industrial de Santander, National Institute of Health, Hospital Italiano de Buenos Aires, Universidad Centro-Occidental Lisandro Alvarado, Epidemiology and Microbiology Institute, Universidade Federal de Minas Gerais (UFMG), World Health Organization, Middlesex University, and Wellcome Trust
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AWARENESS ,Latin Americans ,030231 tropical medicine ,Population ,1117 Public Health and Health Services ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,NCD Risk Factor Collaboration (NCD-RisC)—Americas Working Group ,Medicine ,030212 general & internal medicine ,education ,Public, Environmental & Occupational Health ,Cardiometabolic risk ,education.field_of_study ,Science & Technology ,HYPERTENSION ,business.industry ,1. No poverty ,LATIN-AMERICA ,General Medicine ,Anthropometry ,medicine.disease ,Obesity ,PREVALENCE ,3. Good health ,Blood pressure ,Pooled analysis ,WORLDWIDE TRENDS ,OBESITY ,business ,Life Sciences & Biomedicine ,purl.org/pe-repo/ocde/ford#3.02.18 [http] ,0605 Microbiology ,Demography - Abstract
Made available in DSpace on 2022-04-28T19:28:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 National Cancer Institute National Institute of Mental Health National Heart, Lung, and Blood Institute Fogarty International Center Alliance for Health Policy and Systems Research Medical Research Council Background Describing the prevalence and trends of cardiometabolic risk factors that are associated with noncommunicable diseases (NCDs) is crucial for monitoring progress, planning prevention, and providing evidence to support policy efforts. We aimed to analyse the transition in body-mass index (BMI), obesity, blood pressure, raised blood pressure, and diabetes in the Americas, between 1980 and 2014. Methods We did a pooled analysis of population-based studies with data on anthropometric measurements, biomarkers for diabetes, and blood pressure from adults aged 18 years or older. A Bayesian model was used to estimate trends in BMI, raised blood pressure (systolic blood pressure =140 mm Hg or diastolic blood pressure =90 mm Hg), and diabetes (fasting plasma glucose =7.0 mmol/L, history of diabetes, or diabetes treatment) from 1980 to 2014, in 37 countries and six subregions of the Americas. Findings 389 population-based surveys from the Americas were available. Comparing prevalence estimates from 2014 with those of 1980, in the non-English speaking Caribbean subregion, the prevalence of obesity increased from 3.9% (95% CI 2.2-6.3) in 1980, to 18.6% (14.3-23.3) in 2014, in men; and from 12.2% (8.2-17.0) in 1980, to 30.5% (25.7-35.5) in 2014, in women. The English-speaking Caribbean subregion had the largest increase in the prevalence of diabetes, from 5.2% (2.1-10.4) in men and 6.4% (2.6-10.4) in women in 1980, to 11.1% (6.4-17.3) in men and 13.6% (8.2-21.0) in women in 2014). Conversely, the prevalence of raised blood pressure has decreased in all subregions; the largest decrease was found in North America from 27.6% (22.3-33.2) in men and 19.9% (15.8-24.4) in women in 1980, to 15.5% (11.1-20.9) in men and 10.7% (7.7-14.5) in women in 2014. Interpretation Despite the generally high prevalence of cardiometabolic risk factors across the Americas, estimates also showed a high level of heterogeneity in the transition between countries. The increasing prevalence of obesity and diabetes observed over time requires appropriate measures to deal with these public health challenges. Our results support a diversification of health interventions across subregions and countries. Universidad Peruana Cayetano Heredia Imperial College London Pontificia Universidad Catolica de Chile University of the West Indies University of Sao Paulo Miami Veterans Affairs Healthcare System University of Kent Cleveland Clinic Yale University Caja Costarricense de Seguro Social Instituto Mexicano Del Seguro Social Instituto Nacional de Ciencias Medicas y Nutricion Universidad de Cuenca Federal University of Pelotas Pan American Health Organization University of Pernambuco Dalhousie University Federal University of Maranhao CAFAM University Foundation University Medical Science Universidad de la Republica Centro de Educacion Medica e Investigaciones Clinicas University of Amsterdam Canadian Fitness and Lifestyle Research Institute Universidade Federal de Juiz de Fora Universidade Estadual Paulista Universidade Federal de Santa Catarina University of Montreal Universidade Do Vale Do Rio Dos Sinos National Council of Scientific and Technical Research Ministry of Health Instituto Nacional de Salud Publica Federal University of Sao Paulo Hospital de Clinicas de Porto Alegre Universidade Federal Do Rio Grande Do sul McGill University Andes Clinic of Cardio-Metabolic Studies National Institute of Hygiene Epidemiology and Microbiology Universidad Icesi State University of Montes Claros King's College London Institute for Clinical Effectiveness and Health Policy National Institute of Public Health Universidad Autonoma de Bucaramanga Kingston General Hospital Heart Institute Fundacion Oftalmologica de Santander Simon Fraser University Institute of Tropical Medicine Ministerio de Salud Publica Harvard TH Chan School of Public Health West Virginia University Oswaldo Cruz Foundation Rene Rachou Research Institute Universidade Federal de Ouro Preto Hospital Israelita Albert Einstein Emory University Gorgas Memorial Institute of Health Studies Statistics Canada Gorgas Memorial Institute of Public Health University of Vale Do Rio Dos Sinos University of Puerto Rico Medical Sciences Campus University of Wisconsin-Madison Minas Gerais State Secretariat for Health Universidade Nove de Julho Public Health Agency of Canada Universidad Industrial de Santander National Institute of Health University of Sao Paulo Clinics Hospital Hospital Italiano de Buenos Aires Federal University of Santa Catarina Universidad Centro-Occidental Lisandro Alvarado Epidemiology and Microbiology Institute Universidade Federal de Minas Gerais World Health Organization Middlesex University Universidade Estadual Paulista National Cancer Institute: 1P20CA217231 National Institute of Mental Health: 1U19MH098780 National Heart, Lung, and Blood Institute: 1UM1HL134590 National Heart, Lung, and Blood Institute: 5U01HL114180 Fogarty International Center: D71TW010877 National Heart, Lung, and Blood Institute: HHSN268200900033C Alliance for Health Policy and Systems Research: HQHSR1206660 Medical Research Council: MR/P008984/1 Medical Research Council: MR/P02386X/1 Medical Research Council: MR/P024408/1 Fogarty International Center: R21TW009982
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- 2020
6. Overview of TAE technologies’ HHFW project on LAPD
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X. Yang, M. Binderbauer, Y. Song, T. Carter, R. Goulding, Q. Yang, G. Chen, J. Schroeder, T. DeHaas, B. Van Compernolle, F. Ceccherini, L. Galeotti, I. Allfrey, S. Dettrick, A. Sibley, P. Feng, T. Valentine, W. Waggoner, C. Lau, S. Shiraiwa, J. Wright, N. Bertelli, M. Ono, and W. Horton
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Coupling ,Full wave ,Physics::Plasma Physics ,Wave propagation ,Computer science ,business.industry ,Harmonic ,Mechanical design ,Antenna (radio) ,Aerospace engineering ,business ,Electromagnetic simulation - Abstract
Simulation survey performed at TAE Technologies, has demonstrated that high harmonic fast wave (HHFW) heating is a promising scenario to heat core electrons of FRC plasma. To prepare the proposed experimental study of HHFW antenna-plasma coupling and wave propagation on LAPD machine at UCLA, a high-power-capable 4-strap antenna has been calculated and designed through collaboration among TAE, ORNL, ASIPP, and UCLA. This antenna was mechanically designed and fabricated by ASIPP and it has been installed recently on LAPD. Meanwhile, by using the Petra-M code, a newly developed generic electromagnetic simulation tool for modeling RF wave propagation, the RF-SciDAC team starts 3D full wave simulations. Detailed information on antenna electromagnetic simulations and mechanical design, as well as preliminary experimental results of wave propagation study with the newly installed phased- array antenna, will be presented in this paper.
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- 2020
7. Modulation of methotrexate-induced intestinal mucosal injury by dietary factors
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Seiya Mizuno, S Yuhara, Naoyuki Tsuchiya, Shomi Oka, M Yoshimura, Takashi Higuchi, Shigeto Tohma, M Ono, T Naito, Satoru Takahashi, Eiji Warabi, K Tanaka, and Hiroshi Furukawa
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0301 basic medicine ,Male ,medicine.medical_specialty ,Sucrose ,Health, Toxicology and Mutagenesis ,Toxicology ,Diet, High-Fat ,Pathogenesis ,Excretion ,03 medical and health sciences ,Feces ,0302 clinical medicine ,Oral administration ,Internal medicine ,medicine ,Metabolome ,Animals ,Tissue Distribution ,Intestinal Mucosa ,skin and connective tissue diseases ,business.industry ,General Medicine ,Neomycin ,Survival Analysis ,Gastrointestinal Microbiome ,Mice, Inbred C57BL ,Disease Models, Animal ,Intestinal Diseases ,030104 developmental biology ,Endocrinology ,Methotrexate ,030220 oncology & carcinogenesis ,Toxicity ,business ,medicine.drug - Abstract
Methotrexate (MTX)-induced intestinal mucosal injury in animals has been studied to understand how MTX can cause gastrointestinal disorders, but the pathogenesis of gastrointestinal disorders is still uncertain. We have attempted to reveal how dietary factors influence intestinal toxicity due to MTX. Mice were fed normal chow (NC) or a high-fat high-sucrose diet (HFHSD) before oral administration of MTX. While MTX significantly decreased the survival rates of mice fed HFHSD, the intestinal epithelial injury was detected. MTX excretion in the feces of mice fed HFHSD was reduced. Change of diets between NC and HFHSD influences the survival. The survival rates of the mice fed a high-sucrose diet or control diet were higher than those fed HFHSD. Higher survival rates were observed in mice fed a high-fat high-sucrose diet modified (HFHSD-M) in which casein was replaced by soybean-derived proteins. The survival rates of mice treated with vancomycin were lower than those administered neomycin. Microbiome and metabolome analyses on feces suggest a similarity of the intestinal environments of mice fed NC and HFHSD-M. HFHSD may modify MTX-induced toxicity in intestinal epithelia on account of an altered MTX distribution as a result of change in the intestinal environment.
- Published
- 2019
8. WEST actively cooled load resilient ion cyclotron resonance heating system results
- Author
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L. Colas, Nicola Bertelli, West Team, R. Ragona, Cornwall Lau, Patrick Mollard, E. Delmas, P. Garibaldi, Y. P. Zhao, A. Ekedahl, H. D. Xu, C. Christopher Klepper, Yinglin Song, Bo Lu, Shuai Yuan, E. Lerche, G.M. Wallace, Elijah Martin, F. Durodié, N. Faure, Walid Helou, G.T. Hoang, Karl Vulliez, Patrick Maget, Qingxi Yang, Jean-Marc Delaplanche, J.M. Bernard, Clarisse Bourdelle, C. Desgranges, F. Ferlay, Julien Hillairet, G Urbanczyk, M. Ono, M. Goniche, C. Guillemaut, Y.M. Wang, Daniele Milanesio, V. Bobkov, Z. Chen, R. J. Dumont, F Durand, Riccardo Maggiora, Syun'ichi Shiraiwa, R. Volpe, Gilles Lombard, Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), ITER organization (ITER), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP), Ecole Royale Militaire / Koninklijke Militaire School (ERM KMS), Princeton Plasma Physics Laboratory (PPPL), Princeton University, Max-Planck-Institut für Plasmaphysik [Garching] (IPP), Oak Ridge National Laboratory [Oak Ridge] (ORNL), UT-Battelle, LLC, Southwestern Institute of Physics, Politecnico di Torino = Polytechnic of Turin (Polito), Laboratoire d'Innovation pour les Technologies des Energies Nouvelles et les nanomatériaux (LITEN), Institut National de L'Energie Solaire (INES), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Plasma Science and Fusion Center (PSFC), Massachusetts Institute of Technology (MIT), The WEST team, Southwestern Institute of Physics (SWIP), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Nuclear and High Energy Physics ,WEST ,Materials science ,Phase (waves) ,02 engineering and technology ,7. Clean energy ,01 natural sciences ,010305 fluids & plasmas ,[PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph] ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,ICRF ,business.industry ,[SPI.PLASMA]Engineering Sciences [physics]/Plasmas ,020206 networking & telecommunications ,Plasma ,Condensed Matter Physics ,ion cyclotronion cyclotron resonance heating ICRH ,ICRH ,High-confinement mode ,[SPI.ELEC]Engineering Sciences [physics]/Electromagnetism ,Ion cyclotron resonance heating ,Optoelectronics ,Resilience (materials science) ,Antenna (radio) ,business - Abstract
International audience; Three identical new WEST Ion Cyclotron Resonance Heating (ICRH) antennas have been designed, assembled then commissioned on plasma from 2013 to 2019. The WEST ICRH system is both load-resilient and compatible with long-pulse operations. The three antennas have been successfully operated together on plasma in 2019 and 2020. The load resilience capability has been demonstrated and the antenna feedback controls for phase and matching have been developed. The breakdown detection systems have been validated and successfully protected the antennas. The use of ICRH in combination with Lower Hybrid has triggered the first high confinement mode transitions identified on WEST.
- Published
- 2021
9. Multi-energy reconstructions, central electron temperature measurements, and early detection of the birth and growth of runaway electrons using a versatile soft x-ray pinhole camera at MST
- Author
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M. Rissi, B. E. Chapman, B. C. Stratton, N. C. Hurst, T. Barbui, B. Luethi, Hibiki Yamazaki, Manfred Bitter, K. W. Hill, N. A. Pablant, Patrick Vanmeter, M. Ono, Tilman Donath, L. M. Reusch, J. S. Sarff, L. F. Delgado-Aparicio, O. Chellai, P. Hofer, Yuichi Takase, John C. Wallace, N. Pilet, S. Kojima, D.J. Den Hartog, A. F. Almagari, and Karsten McCollam
- Subjects
010302 applied physics ,Physics ,Photon ,Tokamak ,business.industry ,Detector ,01 natural sciences ,Madison Symmetric Torus ,010305 fluids & plasmas ,law.invention ,Optics ,law ,0103 physical sciences ,Emissivity ,Pinhole camera ,Electron temperature ,business ,Instrumentation ,Smoothing - Abstract
A multi-energy soft x-ray pinhole camera has been designed, built, and deployed at the Madison Symmetric Torus to aid the study of particle and thermal transport, as well as MHD stability physics. This novel imaging diagnostic technique employs a pixelated x-ray detector in which the lower energy threshold for photon detection can be adjusted independently on each pixel. The detector of choice is a PILATUS3 100 K with a 450 μm thick silicon sensor and nearly 100 000 pixels sensitive to photon energies between 1.6 and 30 keV. An ensemble of cubic spline smoothing functions has been applied to the line-integrated data for each time-frame and energy-range, obtaining a reduced standard-deviation when compared to that dominated by photon-noise. The multi-energy local emissivity profiles are obtained from a 1D matrix-based Abel-inversion procedure. Central values of Te can be obtained by modeling the slope of the continuum radiation from ratios of the inverted radial emissivity profiles over multiple energy ranges with no a priori assumptions of plasma profiles, magnetic field reconstruction constraints, high-density limitations, or need of shot-to-shot reproducibility. In tokamak plasmas, a novel application has recently been tested for early detection, 1D imaging, and study of the birth, exponential growth, and saturation of runaway electrons at energies comparable to 100 × Te,0; thus, early results are also presented.
- Published
- 2021
10. Cohort Profile: The Cohorts Consortium of Latin America and the Caribbean (CC-LAC)
- Author
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Leila Beltrami Moreira, Betty S Manrique-Espinoza, Elard Koch, Dalia Stern, Catterina Ferreccio, Claudia Bambs, Adrian Cortes-Valencia, Ione Jayce Ceola Schneider, Marselle B Amadio, José Geraldo Mill, José Boggia, Gilbert Brenes-Camacho, Lariane M Ono, Alvaro Cc Maciel, Walter G Espeche, Poli Mara Spritzer, Fernando Luiz Herkenhoff, J. Jaime Miranda, Adolfo Rubinstein, Horacio A Carbajal, Cecilia Baccino, Andrea R. V. R. Horimoto, Anselm Hennis, Gonzalo Grazioli, Mariachiara Di Cesare, Katia Vergetti Bloch, Ricardo Oliveira Guerra, Gloria L. Beckles, João Luiz Bastos, Álvaro Ruiz-Morales, Alexandre C. Pereira, Ramon A Sanchez, Fiorella Tartaglione, Antonio Bernabe-Ortiz, Roberto de Sa Cunha, Luis Rosero-Bixby, Vilma Irazola, Rodrigo M. Carrillo-Larco, Martin R Salazar, Thiago L N Silva, Pollyanna Kássia de Oliveira Borges, Ian Hambleton, Juan E. Blümel, Flávio Danni Fuchs, Aaron Salinas-Rodriguez, Ramón Álvarez-Vaz, Eleonora d'Orsi, David Alejandro González-Chica, Paulo A. Lotufo, Sérgio Viana Peixoto, Sandra Cortés, Goodarz Danaei, Rosalba Rojas-Martínez, Suely Godoy Agostinho Gimeno, Karen Glazer Peres, Jackie A. Cooper, Maria Fernanda Lima-Costa, Larissa Pruner Marques, Marco Aurélio Peres, Nohora I Rodriguez, William H. Dow, Edward W. Gregg, Laura Gutierrez, Clicerio González-Villalpando, Liam Smeeth, Jorge Tartaglione, Miguel Bravo, Oscar Muñoz, Maria S. Castillo Rascon, Karen Oppermann, María-Elena González-Villalpando, Blanca H. Ceballos, Susana Cararo Confortin, Ruy Lopez-Ridaura, Majid Ezzati, Andrea Huidobro, Carlos A. Aguilar-Salinas, Verônica Colpani, Sandra C. Fuchs, Nelson A S Silva, Donaji Gomez-Velasco, Pablo Perel, Martin Lajous, and Carla de Oliveira Bernardo
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Framingham Risk Score ,Latin Americans ,Epidemiology ,business.industry ,General Medicine ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Health care ,Cohort ,Global health ,Medicine ,AcademicSubjects/MED00860 ,030212 general & internal medicine ,business ,Cohort Profiles ,Disease burden ,Demography ,Cohort study - Abstract
Why was the cohort set up? Latin America and the Caribbean (LAC) are characterized by much diversity in terms of socio-economic status, ecology, environment, access to health care,1,2 as well as the frequency of risk factors for and prevalence or incidence of non-communicable diseases;3–7 importantly, these differences are observed both between and within countries in LAC.8,9 LAC countries share a large burden of non-communicable (e.g. diabetes and hypertension) and cardiovascular (e.g. ischaemic heart disease) diseases, with these conditions standing as the leading causes of morbidity, disability and mortality in most of LAC.10–12 These epidemiological estimates—e.g. morbidity—cannot inform about risk factors or risk prediction, which are relevant to identify prevention avenues. Cohort studies, on the other hand, could provide this evidence. Pooled analysis, using data from multiple cohort studies, have additional strengths such as increased statistical power and decreased statistical uncertainty.13 LAC cohort studies have been under-represented,14 or not included at all,15–17 in international efforts aimed at pooling data from multiple cohort studies. We therefore set out to pool data from LAC cohorts to address research questions that individual cohort studies would not be able to answer. Drawing from previous successful regional enterprises (e.g. Asia Pacific Cohort Studies Collaboration),18,19 we established the Cohorts Consortium of Latin America and the Caribbean (CC-LAC). The main aim of the CC-LAC is to start a collaborative cohort data pooling in LAC to examine the association between cardio-metabolic risk factors (e.g. blood pressure, glucose and lipids) and non-fatal and fatal cardiovascular outcomes (e.g. stroke or myocardial infarction). In so doing, we aim to provide regional risk estimates to inform disease burden metrics, as well as other ambitious projects including a cardiovascular risk score to strengthen cardiovascular prevention in LAC. Initial funding has been provided by a fellowship from the Wellcome Trust Centre for Global Health Research at Imperial College London (Strategic Award, Wellcome Trust–Imperial College Centre for Global Health Research, 100693/Z/12/Z). Additional funding is being provided by an International Training Fellowship from the Wellcome Trust (214185/Z/18/Z). At the time of writing, the daily operations and pooled database are hosted at Imperial College London, though a mid-term goal is to transfer this expertise and operations to LAC. The collaboration relies fundamentally on a strong regional network of health researchers and practitioners
- Published
- 2020
11. PRO12 Investigation of Consistency of Haemophilia a Care in JAPAN: A Claims-Based Cohort Study
- Author
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H. Ueda, M. Ono, A. Oh, Y. Miyaguchi, E. Kinai, and M. Ota
- Subjects
medicine.medical_specialty ,business.industry ,Consistency (statistics) ,Health Policy ,Family medicine ,Economics, Econometrics and Finance (miscellaneous) ,Haemophilia A ,Medicine ,business ,medicine.disease ,Pharmacology, Toxicology and Pharmaceutics (miscellaneous) ,Cohort study - Published
- 2020
12. Anti-E alloimmunization in a pregnancy with a low antibody titer
- Author
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K. Murakami, M. Ono, S. Kitamura, Kazuo Sengoku, A. Nozawa, E. Nakamura, K. Nakanishi, Toshinobu Miyamoto, and Y. Oishi
- Subjects
Pregnancy ,Reproductive Medicine ,business.industry ,Immunology ,Antibody titer ,medicine ,Obstetrics and Gynecology ,medicine.disease ,business - Published
- 2020
13. Simulation, design, and first test of a multi-energy soft x-ray (SXR) pinhole camera in the Madison Symmetric Torus (MST)
- Author
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L. F. Delgado-Aparicio, Hibiki Yamazaki, P. C. Efthimion, D.J. Den Hartog, B. Luethi, L. M. Reusch, M. Rissi, Akira Ejiri, John C. Wallace, N. A. Pablant, T. Donath, J Maddox, P.J. Weix, M. Ono, K. W. Hill, Yuichi Takase, B. Stratton, Patrick Vanmeter, John Goetz, Mark Nornberg, A. F. Almagari, and J. S. Sarff
- Subjects
010302 applied physics ,Physics ,Pixel ,Reversed field pinch ,business.industry ,Detector ,Plasma ,01 natural sciences ,Madison Symmetric Torus ,010305 fluids & plasmas ,law.invention ,Optics ,law ,0103 physical sciences ,Emissivity ,Pinhole camera ,business ,Instrumentation ,Energy (signal processing) - Abstract
A multi-energy soft x-ray pinhole camera has been designed and built for the Madison Symmetric Torus reversed field pinch to aid the study of particle and thermal-transport, as well as MHD stability physics. This novel imaging diagnostic technique combines the best features from both pulse-height-analysis and multi-foil methods employing a PILATUS3 x-ray detector in which the lower energy threshold for photon detection can be adjusted independently on each pixel. Further improvements implemented on the new cooled systems allow a maximum count rate of 10 MHz per pixel and sensitivity to the strong Al and Ar emission between 1.5 and 4 keV. The local x-ray emissivity will be measured in multiple energy ranges simultaneously, from which it is possible to infer 1D and 2D simultaneous profile measurements of core electron temperature and impurity density profiles with no a priori assumptions of plasma profiles, magnetic field reconstruction constraints, high-density limitations, or need of shot-to-shot reproducibility. The expected time and space resolutions will be 2 ms and
- Published
- 2018
14. The hybrid energy spectrum of Telescope Array’s Middle Drum Detector and surface array
- Author
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R.U. Abbasi, M. Abe, T. Abu-Zayyad, M.G. Allen, R. Anderson, R. Azuma, E. Barcikowski, J.W. Belz, D.R. Bergman, S.A. Blake, R. Cady, M.J. Chae, B.G. Cheon, J. Chiba, M. Chikawa, W.R. Cho, T. Fujii, M. Fukushima, T. Goto, W. Hanlon, Y. Hayashi, N. Hayashida, K. Hibino, K. Honda, D. Ikeda, N. Inoue, T. Ishii, R. Ishimori, H. Ito, D. Ivanov, C.C.H. Jui, K. Kadota, F. Kakimoto, O. Kalashev, K. Kasahara, H. Kawai, S. Kawakami, S. Kawana, K. Kawata, E. Kido, H.B. Kim, J.H. Kim, S. Kitamura, Y. Kitamura, V. Kuzmin, Y.J. Kwon, J. Lan, S.I. Lim, J.P. Lundquist, K. Machida, K. Martens, T. Matsuda, T. Matsuyama, J.N. Matthews, M. Minamino, K. Mukai, I. Myers, K. Nagasawa, S. Nagataki, T. Nakamura, T. Nonaka, A. Nozato, S. Ogio, J. Ogura, M. Ohnishi, H. Ohoka, K. Oki, T. Okuda, M. Ono, A. Oshima, S. Ozawa, I.H. Park, M.S. Pshirkov, D.C. Rodriguez, G. Rubtsov, D. Ryu, H. Sagawa, N. Sakurai, A.L. Sampson, L.M. Scott, P.D. Shah, F. Shibata, T. Shibata, H. Shimodaira, B.K. Shin, H.S. Shin, J.D. Smith, P. Sokolsky, R.W. Springer, B.T. Stokes, S.R. Stratton, T.A. Stroman, T. Suzawa, M. Takamura, M. Takeda, R. Takeishi, A. Taketa, M. Takita, Y. Tameda, H. Tanaka, K. Tanaka, M. Tanaka, S.B. Thomas, G.B. Thomson, P. Tinyakov, I. Tkachev, H. Tokuno, T. Tomida, S. Troitsky, Y. Tsunesada, K. Tsutsumi, Y. Uchihori, S. Udo, F. Urban, G. Vasiloff, T. Wong, R. Yamane, H. Yamaoka, K. Yamazaki, J. Yang, K. Yashiro, Y. Yoneda, S. Yoshida, H. Yoshii, R. Zollinger, and Z. Zundel
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Physics ,Physics::Instrumentation and Detectors ,business.industry ,Astrophysics::High Energy Astrophysical Phenomena ,Detector ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astronomy and Astrophysics ,Cosmic ray ,Drum ,Scintillator ,law.invention ,Telescope ,Optics ,Air shower ,law ,Ultra-high-energy cosmic ray ,business ,Energy (signal processing) - Abstract
The Telescope Array experiment studies ultra high energy cosmic rays using a hybrid detector. Fluorescence telescopes measure the longitudinal development of the extensive air shower generated when a primary cosmic ray particle interacts with the atmosphere. Meanwhile, scintillator detectors measure the lateral distribution of secondary shower particles that hit the ground. The Middle Drum (MD) fluorescence telescope station consists of 14 telescopes from the High Resolution Fly’s Eye (HiRes) experiment, providing a direct link back to the HiRes measurements. Using the scintillator detector data in conjunction with the telescope data improves the geometrical reconstruction of the showers significantly, and hence, provides a more accurate reconstruction of the energy of the primary particle. The Middle Drum hybrid spectrum is presented and compared to that measured by the Middle Drum station in monocular mode. Further, the hybrid data establishes a link between the Middle Drum data and the surface array. A comparison between the Middle Drum hybrid energy spectrum and scintillator Surface Detector (SD) spectrum is also shown.
- Published
- 2015
15. SU-E-I-91: Development of a Compact Radiographic Simulator Using Microsoft Kinect
- Author
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K Kozono, Hidetaka Arimura, Yoshiyuki Umezu, A. Mizoguchi, M. Aoki, Y. Kamikawa, Fukai Toyofuku, and M Ono
- Subjects
medicine.diagnostic_test ,Computer science ,business.industry ,Radiography ,Computed tomography ,General Medicine ,Imaging phantom ,Computational photography ,Position (vector) ,medicine ,Medical imaging ,Calibration ,Irradiation ,Image sensor ,Projection (set theory) ,business ,Image resolution ,Rotation (mathematics) ,Simulation - Abstract
Purpose:Radiographic simulator system is useful for learning radiographic techniques and confirmation of positioning before x‐ray irradiation. Conventional x‐ray simulators have drawbacks in cost and size, and are only applicable to situations in which position of the object does not change. Therefore, we have developed a new radiographic simulator system using an infrared‐ray based three‐dimensional shape measurement device (Microsoft Kinect). Methods: We made a computer program using OpenCV and OpenNI for processing of depth image data obtained from Kinect, and calculated the exact distance from Kinect to the object by calibration. Theobject was measured from various directions, and positional relationship between the x‐ray tube and the object was obtained. X‐ray projection images were calculated by projecting x‐rays onto the mathematical three‐dimensional CT data of a head phantom with almost the same size. The object was rotated from 0 degree (standard position) through 90 degrees in increments of 10 degrees, and the accuracy of the measured rotation angle values was evaluated. In order to improve the computational time, the projection image size was changed (512*512, 256*256, and 128*128). Results: The x‐ray simulation images corresponding to the radiographicimages produced by using the x‐ray tube were obtained. The three‐dimensional position of the object was measured with good precision from 0 to 50 degrees, but above 50 degrees, measured position error increased with the increase of the rotation angle. The computational time and image size were 30, 12, and 7 seconds for 512*512, 256*256, and 128*128, respectively. Conclusions: We could measure the three‐dimensional position of the object using properly calibrated Kinect sensor, and obtained projection images at relatively high‐speed using the three‐dimensional CTdata. It was suggested that this system can be used for obtaining simulated projection x‐ray images before x‐ray exposure by attaching this device onto an x‐ray tube.
- Published
- 2017
16. Defect-based compact modeling for RTN and BTI variability
- Author
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Praveen Raghavan, Alessio Spessot, S. Yamakawa, Marko Simicic, M. Ono, Pieter Weckx, Anda Mocuta, Bertrand Parvais, K. Nomoto, Diederik Verkest, Ben Kaczer, Ken Sawada, Dimitri Linten, and H. Ammo
- Subjects
010302 applied physics ,Engineering ,business.industry ,Hardware_PERFORMANCEANDRELIABILITY ,02 engineering and technology ,01 natural sciences ,Noise (electronics) ,020202 computer hardware & architecture ,Threshold voltage ,Data modeling ,Reliability (semiconductor) ,Logic gate ,Black box ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,Electronic design automation ,Voltage source ,business - Abstract
This paper describes a defect-centric based compact modeling methodology for time-dependent threshold voltage variability (V TH ), induced by Bias Temperature Instability (BTI) and Random Telegraph Noise (RTN). A Verilog-A based model wrapper is used to implement a threshold voltage shift by adding a variable voltage source at the gate of the core device model. This compact model allows to incorporate all BTI and RTN related electrostatics and kinetics in standard EDA-tools as a ‘black box’ without any custom simulation flow. It can therefore be used in either a manual configuration for academic purposes or be integrated as is into industry standard EDA tools and simulation flows.
- Published
- 2017
17. The first nurse practitioner graduate programme in <scp>J</scp> apan
- Author
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M. Ono, M. Tonai, Shinji Miyauchi, Hiromi Fukuda, J.K. Magilvy, and Sachiyo Murashima
- Subjects
education.field_of_study ,business.industry ,Nurse practitioners ,Population ,Nurse Practitioner ,Nursing Education ,Homecare ,Nurse Practitioner Education ,Nursing Homes ,Oncology nursing ,Nursing care ,Japan ,Nursing ,Graduate level ,Humans ,Medicine ,Nurse Practitioners ,Credentialing ,business ,Nursing homes ,education ,Education, Nursing, Graduate ,General Nursing ,Super-Ageing Populations - Abstract
Aim This paper describes the establishment of the first Japanese nurse practitioner graduate programme and legislative activities to institutionalize nurse practitioners in Japan. Background To address the super-ageing population, Oita University of Nursing and Health Sciences initiated the first academic graduate level nurse practitioner programme in Japan, based upon the global standard defined by the International Council of Nurses. Conclusion In 2010, Oita University of Nursing and Health Sciences graduated the first nurse practitioner. We believe that nurse practitioners will be highly valued in Japan for thoughtful nursing care to the fragile elders living in rural and urban Japan.
- Published
- 2014
18. Design Details of the Transient CHI Plasma Start-up System on NSTX-U
- Author
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Stephen Jardin, Roger Raman, D. Mueller, Brian Nelson, Jonathan Menard, M. Ono, Thomas Jarboe, and C. Neumeyer
- Subjects
Physics ,Nuclear and High Energy Physics ,Tokamak ,business.industry ,Divertor ,Nuclear engineering ,Electrical engineering ,Solenoid ,Plasma ,Condensed Matter Physics ,law.invention ,Front and back ends ,Physics::Plasma Physics ,law ,Nuclear fusion ,Transient (oscillation) ,Coaxial ,business - Abstract
Elimination of the central solenoid would simplify the engineering design of a fusion nuclear science facility and tokamak based devices. The method of transient coaxial helicity injection (CHI) has successfully demonstrated formation of a high-quality closed flux plasma in NSTX and will be used as the front end of the start-up method for a full demonstration of noninductive current start-up, followed by noninductive current ramp-up using neutral beams in the NSTX-U device that is now under construction at the Princeton Plasma Physics Laboratory. CHI is implemented by driving current along open field lines that connect the lower inner and outer divertor plates of a spherical torus. The engineering system requirements and the design of the CHI system on NSTX-U are described.
- Published
- 2014
19. Moderne Therapiestrategien bei Fallot-Tetralogie
- Author
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H. Niehaus and M. Ono
- Subjects
Pulmonary and Respiratory Medicine ,Gynecology ,medicine.medical_specialty ,business.industry ,medicine ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Abstract
Die Fallot-Tetralogie gehort zu den haufigsten angeborenen Herzerkrankungen und war eine der ersten, die einer chirurgischen Therapie zuganglich waren. Derzeitig ist die primare Korrekturoperation im Sauglingsalter die Therapie der Wahl. Diese kann auch beim symptomatischen Neugeborenen mit guten Ergebnissen durchgefuhrt werden. Indikationen fur eine palliative Therapie werden kontrovers diskutiert und stellen heutzutage eher die Ausnahme dar. Dennoch kann eine Palliation, z. B. bei besonderen Risikofaktoren, weiterhin indiziert sein. Neben den chirurgischen Verfahren stehen hierzu auch moderne katheterinterventionelle Techniken zur Verfugung. Die Korrekturoperation wird heute standardmasig uber einen transatrialen Zugang durchgefuhrt, ggf. in Kombination mit einer begrenzten Infundibulotomie. Auf ein transanulares Vorgehen im Bereich des rechtsventrikularen Ausflusstrakts wird moglichst verzichtet. Ziel ist die Vermeidung einer Pulmonalklappeninsuffizienz, die langfristig zu einer irreversiblen Beeintrachtigung der rechtsventrikularen Funktion fuhren kann. Sie stellt heute das fuhrende Problem im Langzeitverlauf dar. Aktuelle Entwicklungen, wie der interventionelle Pulmonalklappenersatz und mithilfe des „tissue engineering“ hergestellte Herzklappen, konnten in Zukunft das Risiko der Reeingriffe deutlich reduzieren oder diese vollstandig vermeiden.
- Published
- 2014
20. Bad dog: feral and free-roaming dogs as agents of conflict
- Author
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M. Ono, Julie K. Young, and David L. Bergman
- Subjects
0106 biological sciences ,Geography ,Free roaming ,Ecology ,business.industry ,010604 marine biology & hydrobiology ,Internet privacy ,business ,010603 evolutionary biology ,01 natural sciences ,Nature and Landscape Conservation - Published
- 2018
21. Development of high power gyrotrons for advanced fusion devices
- Author
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Hiroshi Idei, Takumi Onchi, Kazuaki Hanada, M. Ono, Fumiya Motoyoshi, Maki Okada, Kazunobu Nagasaki, Tsuyoshi Imai, Ryosuke Ikeda, Yoshika Mitsunaka, Tsuyoshi Kariya, Yasuhisa Oda, Ryutaro Minami, Keishi Sakamoto, Takashi Shimozuma, Hiroyuki R. Takahashi, Tomoharu Numakura, T. Eguchi, Yousuke Nakashima, Yasuo Yoshimura, and Shin Kubo
- Subjects
Physics ,Nuclear and High Energy Physics ,Fusion ,law ,business.industry ,Gyrotron ,Electrical engineering ,Condensed Matter Physics ,business ,Power (physics) ,law.invention - Published
- 2019
22. Endometriosis, endometrium, implantation and fallopian tube
- Author
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C. W. Tan, Y. H. Lee, M. Choolani, H. H. Tan, L. Griffith, J. Chan, P. C. Chuang, M. H. Wu, Y. J. Lin, S. J. Tsai, M. Rahmati, M. Petitbarat, S. Dubanchet, A. Bensussan, G. Chaouat, N. Ledee, L. Bissonnette, D. Haouzi, C. Monzo, S. Traver, S. Bringer, J. Faidherbe, H. Perrochia, O. Ait-Ahmed, H. Dechaud, S. Hamamah, M. G. Ibrahim, M. L. B. de Arellano, M. Sachtleben, V. Chiantera, S. Frangini, S. Younes, A. Schneider, J. Plendl, S. Mechsner, M. Ono, H. Hamai, A. Chikawa, S. Teramura, R. Takata, T. Sugimoto, K. Iwahashi, N. Ohhama, R. Nakahira, M. Shigeta, I. H. Park, K. H. Lee, H. G. Sun, S. G. Kim, J. H. Lee, Y. Y. Kim, H. J. Kim, G. H. Jeon, C. M. Kim, S. Bocca, H. Wang, S. Anderson, L. Yu, J. Horcajadas, S. Oehninger, E. Bastu, M. F. Mutlu, C. Celik, C. Yasa, O. Dural, F. Buyru, F. Quintana, A. Cobo, J. Remohi, M. Ferrando, R. Matorras, A. Bermejo, C. Iglesias, M. Cerrillo, M. Ruiz, D. Blesa, C. Simon, J. A. Garcia-Velasco, L. Chamie, D. M. F. Ribeiro, M. Riboldi, R. Pereira, M. B. Rosa, C. Gomes, P. H. de Mello, P. Fettback, T. Domingues, A. Cambiaghi, A. C. P. Soares, C. Kimati, E. L. A. Motta, P. Serafini, D. K. Hapangama, A. J. Valentijn, H. Al-Lamee, K. Palial, J. A. Drury, T. von Zglinicki, G. Saretzki, C. E. Gargett, C. Y. Liao, Y. J. Sung, H. Y. Li, M. Morotti, V. Remorgida, P. L. Venturini, S. Ferrero, M. Nabeta, A. Iki, H. Hashimoto, M. Koizumi, Y. Matsubara, K. Hamada, T. Fujioka, K. Matsubara, Y. Kusanagi, A. Nawa, A. Zanatta, A. M. da Rocha, J. L. Guerra, B. Cogliati, P. d. M. Bianchi, B. Prieto, A. Exposito, R. Mendoza, A. Rabanal, M. Bedaiwy, L. Yi, W. Dahoud, J. Liu, W. Hurd, T. Falcone, C. Biscotti, S. Mesiano, R. Sugiyama, K. Nakagawa, Y. Nishi, Y. Kuribayashi, S. Akira, A. Germeyer, S. Rosner, J. Jauckus, T. Strowitzki, M. von Wolff, K. N. Khan, M. Kitajima, A. Fujishita, M. Nakashima, H. Masuzaki, T. Kajihara, O. Ishihara, J. Brosens, K. Vezmar, V. Savournin, R. Balet, S. F. Loh, S. R. Tannenbaum, J. K. Y. Chan, A. Scarella, V. Chamy, L. Devoto, M. Abrao, H. Sovino, K. Krasnopolskaya, A. Popov, D. Kabanova, A. Beketova, V. Ivakhnenko, A. Shohayeb, A. Wahba, A. Abousetta, H. al-inany, A. El Daly, M. Zayed, M. Kvaskoff, J. Han, S. A. Missmer, P. Navarro, J. Meola, C. P. Ribas, C. P. Paz, R. A. Ferriani, F. C. Donabela, E. Tafi, U. L. R. Maggiore, C. Scala, J. Hackl, J. Strehl, D. Wachter, R. Dittrich, S. Cupisti, T. Hildebrandt, L. Lotz, M. Attig, I. Hoffmann, S. Renner, A. Hartmann, M. W. Beckmann, F. Urquiza, C. Ferrer, E. Incera, A. Azpiroz, G. Junovich, C. Pappalardo, G. Guerrero, S. Pasqualini, G. Gutierrez, L. Corti, A. M. Sanchez, P. P. Bordignon, P. Santambrogio, S. Levi, P. Persico, P. Vigano, E. Papaleo, S. Ferrari, M. Candiani, L. E. E. van der Houwen, A. M. F. Schreurs, C. B. Lambalk, R. Schats, P. G. A. Hompes, V. Mijatovic, S. Y. Xu, J. Li, X. Y. Chen, S. Q. Chen, L. Y. Guo, D. Mathew, Q. Nunes, B. Lane, D. Fernig, D. Hapangama, T. Lind, M. Hammarstrom, D. Golmann, K. Rodriguez-Wallberg, A. Hestiantoro, A. Cakra, A. Aulia, H. Al-Inany, B. Houston, C. Farquhar, V. Tagliaferri, D. Gagliano, V. Immediata, C. Tartaglia, A. Zumpano, G. Campagna, A. Lanzone, M. Guido, S. Matsuzaki, C. Darcha, R. Botchorishvili, J. L. Pouly, G. Mage, M. Canis, S. B. Shivhare, J. N. Bulmer, B. A. Innes, G. E. Lash, A. A. de Graaff, H. Zandstra, L. J. Smits, J. J. Van Beek, G. A. J. Dunselman, G. Bozdag, P. T. Calis, D. O. Demiralp, B. Ayhan, N. Igci, H. Yarali, N. Acar, H. Er, A. Ozmen, I. Ustunel, E. T. Korgun, K. Kuroda, M. Kuroda, A. Arakawa, M. Kitade, A. I. Brosens, J. J. Brosens, S. Takeda, and T. Yao
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Gynecology ,medicine.medical_specialty ,Obstetrics ,business.industry ,Rehabilitation ,Endometriosis ,Obstetrics and Gynecology ,medicine.disease ,Endometrium ,medicine.anatomical_structure ,Reproductive Medicine ,medicine ,business ,Fallopian tube - Published
- 2013
23. Calibration and Characterization of the IceCube Photomultiplier Tube
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Ignacio Taboada, C. Pérez de los Heros, F. Rothmaier, Peter Mészáros, Matthias Geisler, Todor Stanev, Dawn Williams, M. R. Duvoort, Darren Grant, B. Ruzybayev, F. Descamps, A. Slipak, S. Tilav, H. Miyamoto, Jay Gallagher, J. van Santen, Y. Hasegawa, P. Nießen, A. Tepe, R. L. Imlay, M. Labare, G. Wikström, T. Griesel, R. Franke, C. Walck, A. Schukraft, K. Laihem, R. Ehrlich, Dirk Ryckbosch, K. Beattie, O. Schulz, Thomas K. Gaisser, G. B. Yodh, K. Wiebe, Christian Bohm, M. Krasberg, M. V. D'Agostino, Axel Groß, Q. Swillens, David A. Schneider, A. Olivas, John Clem, Jon Dumm, A. Goldschmidt, G. C. Hill, M. Matusik, M. Prikockis, T. Waldenmaier, Joanna Kiryluk, Michael J. Baker, J. Dreyer, S. Seunarine, J. M. Joseph, A. Laundrie, G. Stephens, Spencer Klein, S. Westerhoff, P. B. Price, Thomas Meures, L. Gladstone, J. J. Beatty, D. Seckel, O. Tarasova, A. Piegsa, Jenni Adams, M. Danninger, A. R. Fazely, P. A. Toale, Klas Hultqvist, N. Milke, C. Ha, Kara Hoffman, Y. Sestayo, M. Merck, H. Landsman, M. L. Benabderrahmane, D. Rutledge, S. Yoshida, J. Posselt, M. Walter, A. Rizzo, Stijn Buitink, T. O. B. Schmidt, George Japaridze, J.-P. Hülß, T. Kowarik, Christian Spiering, Carsten Rott, P. Roth, R. Nahnhauer, Dave Nygren, H. S. Matis, S. H. Seo, N. van Eijndhoven, S. Knops, Justin Vandenbroucke, R. J. Lauer, M. Bissok, O. Engdegård, Paraic A. Kenny, Juanan Aguilar, A. Tamburro, Takao Kuwabara, N. Kitamura, D. Wahl, K. Mase, Reina H. Maruyama, Kurt Woschnagg, Paul Evenson, Wolfgang Rhode, Karen Andeen, D. Berley, C. De Clercq, S. Hickford, R. G. Stokstad, B. Voigt, Xinhua Bai, Christopher Wiebusch, Xianwu Xu, R. Morse, P. Robl, B. Christy, D. Turcan, Francis Halzen, L. Demirörs, J. L. Kelley, Laura C. Bradley, P. Zarzhitsky, P. Berghaus, S. Schlenstedt, O. Depaepe, G. Kroll, Markus Ahlers, K. Rawlins, R. Wischnewski, E. Blaufuss, S. Euler, S. Stoyanov, Dmitry Chirkin, R. Lehmann, P. O. Hulth, J. Eisch, G. de Vries-Uiterweerd, B. Semburg, A. Van Overloop, C. Terranova, O. Fadiran, G. W. Sullivan, Alexander Kappes, A.C. Pohl, Damian Pieloth, H. Wissing, J. Lünemann, S. M. Movit, R. Porrata, James Madsen, T. Krings, D. Hubert, Elisa Resconi, Nathan Whitehorn, E. A. Strahler, J. Berdermann, Ph. Herquet, R. C. Bay, R. W. Ellsworth, Samvel Ter-Antonyan, S. Cohen, M. Ono, D. J. Boersma, T. DeYoung, J. L. Bazo Alba, Kael Hanson, J. K. Becker, T. Abu-Zayyad, J. W. Nam, Hermann Kolanoski, A. Schultes, L. Köpke, T. Straszheim, Pratik Majumdar, H. G. Sander, S. Odrowski, A. Homeier, N. Kemming, James E. Braun, C. Colnard, M. M. Foerster, Larissa Paul, Aya Ishihara, S. Bechet, T. Feusels, Steven W. Barwick, S.J. Lafebre, P. Redl, J. E. Jacobsen, Teresa Montaruli, P. Sandstrom, Allan Hallgren, Paolo Desiati, J. Auffenberg, L. Gerhardt, Rasha Abbasi, Chun Xu, R. Ganugapati, K. Hoshina, E. Middell, Elisa Bernardini, Karl-Heinz Kampert, D. F. Cowen, Kirill Filimonov, Glenn Spiczak, Chris Wendt, Albrecht Karle, M. Kowalski, M. Ribordy, Chad Finley, Subir Sarkar, U. Naumann, A. Silvestri, K. H. Becker, J. P. Rodrigues, T. Stezelberger, J. Petrovic, R. M. Gunasingha, Michael Stamatikos, K. Meagher, S. Hussain, D. J. Koskinen, M. Olivo, J. A. Goodman, S. Grullon, M. J. Carson, S. Panknin, Y. Abdou, Fabian Kislat, J. C. Díaz-Vélez, Timo Karg, D. Z. Besson, J. Haugen, M. Schunck, C. Roucelle, K. Kuehn, D. Bertrand, M. Wallraff, M. Gurtner, B. D. Fox, Dirk Lennarz, Henrik J. Johansson, W. Huelsnitz, K. Helbing, Anna Franckowiak, K. Schatto, G. Kohnen, D. Tosi, Gerald Przybylski, M. Inaba, K. Han, Olga Botner, Max-Planck-Institut für Kernphysik (MPIK), Max-Planck-Gesellschaft, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)
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Nuclear and High Energy Physics ,Photomultiplier ,[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE] ,Photon ,Physics::Instrumentation and Detectors ,[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,Cosmic ray ,Context (language use) ,Astrophysics ,Aetiology, screening and detection [ONCOL 5] ,01 natural sciences ,IceCube Neutrino Observatory ,[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,Optics ,0103 physical sciences ,Neutrino ,Cherenkov ,ddc:530 ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,010303 astronomy & astrophysics ,Instrumentation ,Cosmic rays ,Cherenkov radiation ,Physics ,Ice ,PMT ,010308 nuclear & particles physics ,business.industry ,[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE] ,Astrophysics::Instrumentation and Methods for Astrophysics ,Photonics ,Astrophysics - Instrumentation and Methods for Astrophysics ,business - Abstract
Over 5,000 PMTs are being deployed at the South Pole to compose the IceCube neutrino observatory. Many are placed deep in the ice to detect Cherenkov light emitted by the products of high-energy neutrino interactions, and others are frozen into tanks on the surface to detect particles from atmospheric cosmic ray showers. IceCube is using the 10-inch diameter R7081-02 made by Hamamatsu Photonics. This paper describes the laboratory characterization and calibration of these PMTs before deployment. PMTs were illuminated with pulses ranging from single photons to saturation level. Parameterizations are given for the single photoelectron charge spectrum and the saturation behavior. Time resolution, late pulses and afterpulses are characterized. Because the PMTs are relatively large, the cathode sensitivity uniformity was measured. The absolute photon detection efficiency was calibrated using Rayleigh-scattered photons from a nitrogen laser. Measured characteristics are discussed in the context of their relevance to IceCube event reconstruction and simulation efforts., 40 pages, 12 figures
- Published
- 2016
24. Development of 28/35 GHz dual-frequency gyrotron for ECH study
- Author
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Y. Ebashi, Kimiya Komurasaki, Hiroshi Idei, Tsuyoshi Kariya, Tsuyoshi Imai, Yousuke Nakashima, M. Ono, R. Minami, Kazuaki Hanada, Y. Endo, K. Tsumura, and T. Numakura
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Engineering ,Sapphire window ,Oscillation ,business.industry ,Electrical engineering ,Plasma ,Power (physics) ,law.invention ,Optics ,Transmission (telecommunications) ,law ,Gyrotron ,Dual frequency ,business ,Beam (structure) - Abstract
The high power and long pulse operation of the gyrotron as well as efficient transmission of its output are quite important for achieving improved plasma performances. A 28 GHz 1 MW gyrotron developed for GAMMA 10/PDX achieved an output power of 1.38 MW in 2015 experiment after the power supply was improved. Furthermore, a new 28/35 GHz dual-frequency gyrotron (2 MW 3 s and 0.4 MW CW) for QUEST, NSTX-U, Heliotron J and GAMMA 10/PDX has been fabricated, after the preliminary test of a double-disk sapphire window installed in the gyrotron was performed. In the first experimental test, the oscillation of the main mode was confirmed at a frequency of 28.036 GHz with a Gaussian-like beam and an output power of 1.22 MW.
- Published
- 2016
25. Inflammatory bowel diseases (PP-065)
- Author
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M. Zhang, N. Kamada, A. Kimura, D. M. McKay, Y. Ohno, Z. Cheng, T. Sasaoka, M. Kainoh, K. Hirata, E. Berger, Tonny Lagerweij, M. Irie, H. J. Youn, T. Shibata, D. C. Prescott, K. Matsuo, M. Peter, T. Kawabe, D. Haller, Y. Konishi, J. S. Schaefer, P. Bland, T. Naitoh, N. Mukaida, A. Tominaga, Y. Nemoto, N. Ishii, K. Kaneko, B. Lee, S. Raghavan, T. Hibi, T. Takeuchi, J. Yamashita, F. I. Kostadinova, N. Worms, K. Tsuchiya, M. Ono, S. Thiesen, S. Matsumoto, B. Sredni, N. Nishio, G. Halpert, K. Isobe, Y. Hara, S. Mourits, I. Lee, K. Håkansson, N. Hoogenraad, A. Messlik, M. van Egmond, R. B. Sartor, M. Takahashi, Y. Kaneshiro, J. Klein, A. Asao, B. Atkinson, T. Fromme, H. Fujita, T. Uede, B. K. Popivanova, O. Grip, N. Vigneswaran, H. Funabashi, R. Saito, Y. Takada, T. Totsuka, Y. C. Götlind, I. Chinen, S. Rose-John, L. Rath-Wolfson, T. Matsuo, S. Serada, Y. Kalechman, D. Montufar-Solis, T. Takayama, Y. Azuma, I. Tanaka, S. Ito, C. Waterhouse, E. Rath, H. Tanaka, R. Okamoto, E. F. Wagner, R. Zhang, T. Nakahama, S. C. Kim, H. Nakajima, M. T. Kitazume, Y. Matsuo, N. Watanabe, A. A. Oeij, T. Kishimoto, T. Tahara, H. Susuki, T. Kanai, D. Ardelean, K. Sugamura, T. Takahashi, K. Masuda, A. Yoshida, H. Chinen, M. Nanno, M. Kuwamura, M. Jerkic, M. Watanabe, M. Nagasaka, Rob Mariman, Y. Arita, T. Hisamatsu, M. Ito, K. Nakajima, Lex Nagelkerken, T. Naka, T. K. Khiong, M. Yamamoto, S. Okamoto, M. Klingenspor, B. Liu, T. Taguchi, T. Nakamura, E. H. Hörnquist, M. Narita, F. Terabe, J. Scheller, I. Hirata, Y. Koga, T. Naito, K. Mitsuyama, M. van Erk, M. Letarte, Bas Kremer, J. Wang, and M. Fujimoto
- Subjects
medicine.medical_specialty ,business.industry ,Internal medicine ,Immunology ,medicine ,Immunology and Allergy ,Inflammatory Bowel Diseases ,General Medicine ,business ,Gastroenterology - Published
- 2010
26. Psoriasis and skin diseases (PP-055)
- Author
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N. Esmaeil, K. Ruchusatsawat, L. Komorowski, Esther Reefman, T. Muta, S. Marzouk, Y. Muro, E. V. Kryukova, M. Masjedi, R. Maruyama, A. R. Rezaee, Y. Ogawa, K. Yanaba, Z. Bahloul, S. Yang, N. Hirankarn, T. Ohba, Y. Chan, C. Rose, S. Shibuya, K. Lin, E. Kanno, V. van de Walle, A. Shigeta, M. Ritsu, A. Zuurmond, J. DiGiovanni, Y. Avihingsanon, C. Dähnrich, F. Frikha, Y. Iwakura, S. Yooyongsatit, W. Stoecker, J. Tavakkol Afsahri, M. Mohebali, C. Probst, M. Frigui, A. Okuma, N. Valizadeh, M. Takaishi, S. Emami, T. Kataoka, F. Kuper, B. Tameazyfar, K. Nakajima, M. Chiang, T. Higuchi, S. Haghjoo, W. Schlumberger, I. Bloecker, T. Kanda, K. Miyoshi, A. K. Shirakawa, R. Ludwig, T. Nakayama, S. Aiba, F. Andaleeb, H. Tanno, Y. Tomita, H. Turki, N. Suzuki, A. Momeni, H. Masmoudi, N. Takenaka, N. Kaddour, S. Sato, T. H. Huyen, J. M. Benson, M. F. Naso, K. Hieshima, L. L. Gutshall, E. Schmidt, K. Futamura, H. Saito, H. Rafatpanah Baygi, Lex Nagelkerken, M. Oka, O. Yoshie, K. Fechner, K. Rentzsch, P. Layegh, K. van der Mark, A. Mutirangura, S. Toriyabe, C. Persoon-Deen, A. Uvarovskii, K. Sugiura, T. Takeichi, Z. Shaker, K. Kawakami, J. Wongpiyabovorn, A. Asylian, D. Zillikens, E. V. Svirshchevskaya, B. Esmaeili, Y. Inoue, H. Edamatsu, M. Ono, A. Plomp, K. Matsumoto, H. Lim, S. Hong, H. Kwon, S. Sano, M. Tachi, L. Hu, K. Ishii, O. Tatsiy, M. M. Elloso, A. Yoshizaki, and N. Worms
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medicine.medical_specialty ,business.industry ,Psoriasis ,Immunology ,Immunology and Allergy ,Medicine ,General Medicine ,business ,medicine.disease ,Dermatology - Published
- 2010
27. Clinical and genetic features of 20 Japanese patients with vascular-type Ehlers-Danlos syndrome
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Tomoki Kosho, M. Ono, Shujiro Hayashi, Yoko Aoki, Atsushi Hatamochi, E. Kunii, K. Yamazaki, Toshihiro Tanaka, M. Funakoshi, Keishi Makino, T. Suzuki, T. Isei, Yoshihiko Mitsuhashi, Mari Wataya-Kaneda, and Yayoi Shimaoka
- Subjects
Mutation ,Gastrointestinal tract ,Pathology ,medicine.medical_specialty ,business.industry ,Point mutation ,Perforation (oil well) ,Dermatology ,medicine.disease_cause ,medicine.disease ,Collagen Type III ,Exon ,Ehlers–Danlos syndrome ,medicine ,business ,Gene - Abstract
Summary Background Vascular-type Ehlers–Danlos syndrome (vEDS) is a severe autosomal dominant inherited disorder resulting from mutations within the α1 type III collagen gene (COL3A1). The majority of published mutations are base changes leading to the substitution of single glycine residues within the triple-helical domain of type III collagen. Although clinical characteristics and mutations in the COL3A1 gene have been analysed for some patients from Europe and America, similar analyses have not yet been performed for Japanese patients with vEDS. Objectives To analyse the genetic and phenotypic findings in Japanese patients with vEDS. Methods We analysed the clinical features of 20 unrelated individuals with vEDS. To quantify type III collagen production, the fibroblasts were cultured with 3H-proline, and the radiolabelled collagenous proteins were analysed using sodium dodecyl sulphate–polyacrylamide gel electrophoresis and fluorography. Mutations in COL3A1 were detected by sequence analysis of cDNA from patients’ fibroblasts and subsequently by a genomic DNA sequence analysis. Results Thin and translucent skin with extensive bruising and hypermobility of the small joints were observed in about 90% of the patients, whereas the prevalence of serious clinical findings such as rupture/dissection/aneurysm of the arteries (30%) or rupture of the gastrointestinal tract (25%) was relatively low. Sequence analyses of the COL3A1 gene demonstrated heterozygous point mutations leading to glycine substitution in only nine patients (45%), while heterozygous splice-site mutations at the junction of the triple-helical exons were observed in the remaining 11 patients (55%). The average type III collagen production level in the cultured dermal fibroblasts was 14·6% of the normal value. The types of complication were not associated with specific mutations in COL3A1. Conclusion The analysis in the present series revealed a low frequency of patients presenting with serious clinical findings such as arterial rupture/arterial dissection/aneurysm and perforation or rupture of the gastrointestinal tract, and revealed a higher prevalence of splice-site mutations at the junction of the triple-helical exons than of glycine substitution mutations in COL3A1.
- Published
- 2010
28. Scenario development during commissioning operations on the National Spherical Torus Experiment Upgrade
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M. Ono, Jonathan Menard, W. Guttenfelder, Filippo Scotti, Roger Raman, S.M. Kaye, S.P. Gerhardt, Michael Jaworski, D. Mueller, Nathaniel Ferraro, R.E. Bell, Mario Podesta, B.P. LeBlanc, Jinseop Park, D. J. Battaglia, S.A. Sabbagh, M. D. Boyer, Ahmed Diallo, John Berkery, Vlad Soukhanovskii, F. Bedoya, and Clayton E. Myers
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Physics ,Nuclear and High Energy Physics ,Project commissioning ,business.industry ,Spherical tokamak ,Condensed Matter Physics ,01 natural sciences ,010305 fluids & plasmas ,Upgrade ,Development (topology) ,Real-time Control System ,0103 physical sciences ,Aerospace engineering ,010306 general physics ,business ,National Spherical Torus Experiment - Published
- 2018
29. Design and Experimental Results of Three-Phase Superconducting Fault Current Limiter Using Highly-Resistive YBCO Tapes
- Author
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Takahashi Masahiko, Naoyuki Amemiya, Yasuhiro Iijima, Masami Urata, M. Sakai, Takashi Yazawa, T. Saitoh, H. Takigami, Kei Koyanagi, M. Ono, K. Toba, and Y. Shiohara
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Materials science ,business.industry ,Electrical engineering ,Cryocooler ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,Generator (circuit theory) ,Three-phase ,Electromagnetic coil ,Fault current limiter ,Electrical and Electronic Engineering ,business ,Short circuit ,Circuit breaker ,Voltage - Abstract
As one of the programs in the Ministry of Economy, Trade and Industry (METI) R&D project on coated conductors, we developed a three-phase 6.6 kV superconducting fault current limiter (SFCL) and conducted some evaluation tests. The developed SFCL mainly comprised a set of three-phase current-limiting coils installed in a sub-cooled nitrogen cryostat with a Gifford-McMahon (GM) cryocooler, circuit breakers, and a sequence control circuit. Two tapes were wound in parallel in each limiting coil to obtain a rated current of 72 A rms. AC characteristics of each coil were measured, and relevant performance metrics were obtained. The whole system was installed in a cubicle. Short circuit experiments were then conducted with a short circuit generator. In a three-line ground fault test, the SFCL successfully restricted a short circuit current of over 1.56 kA to about 840 A with an applied voltage of 6.6 kV. The system integration ability and the obtained data show the promise of this approach for practical implementation. The SFCL was ready for user field tests.
- Published
- 2009
30. Superconducting fault current limiter using high-resistive YBCO tapes
- Author
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Takahashi Masahiko, Y. Shiohara, H. Takigami, Takashi Yazawa, Kei Koyanagi, Saito Takashi, Yasuhiro Iijima, M. Ono, N. Ameniya, Masami Urata, and K. Toba
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Materials science ,business.industry ,Energy Engineering and Power Technology ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,Conductor ,Generator (circuit theory) ,Current limiting ,Electromagnetic coil ,Fault current limiter ,Optoelectronics ,Electrical and Electronic Engineering ,business ,Electrical conductor ,Short circuit ,Voltage - Abstract
One of the programs in the Ministry of Economy and Trade and Industry (METI) project regarding R & D on YBCO conductor is to evaluate the applicability of the developed conductor toward several applications. This paper focuses on a fault current limiter (FCL) as one of the expected power applications. YBCO tape conductors with ion beam assisted deposition (IBAD) substrate are used in this work. In order to obtain high resistance of the conductor, which is preferable to an FCL, the thickness of the protecting layer made of silver was decreased as possible. Then high-resistive metal stabilizing layer is attached on the silver layer to improve stability. Obtaining the relevant current limiting performance on short sample experiments, model coils were developed to aim the 6.6 kV-class FCL. Short circuit experiments were implemented with a short circuit generator. The coil successfully restricted the short circuit current over 17 kA to about 700 A by the applied voltage of 3.8 kV, which is nominal phase-to-ground voltage. The experimental results show good agreement with computer analyses and show promising toward the application.
- Published
- 2008
31. Design and Test Results of a Fault Current Limiter Coil Wound With Stacked YBCO Tapes
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Kei Koyanagi, Takashi Yazawa, Masami Urata, Takahashi Masahiko, and M. Ono
- Subjects
Materials science ,business.industry ,Electrical engineering ,Yttrium barium copper oxide ,Power factor ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,law.invention ,Lamination (geology) ,Capacitor ,chemistry.chemical_compound ,chemistry ,law ,Electromagnetic coil ,Fault current limiter ,Electrical and Electronic Engineering ,business ,Rogowski coil ,Coil tap - Abstract
This paper describes the design and test results of a 6.6 kV-class superconducting fault current limiter (FCL) coil wound with YBCO tapes. YBCO tapes, with stainless-steel lamination, were prepared for an experimental FCL coil. The main feature of this FCL coil is winding of multiple YBCO tapes in parallel in order to increase the rated current. To obtain a rated current up to several hundred amps, four tapes, electrically insulated, were wound in parallel to form a non-inductive coil. The coil specifications, such as winding pitch, number of turns, and transpositions, were carefully designed by numerical simulation to equalize the current distribution in each tape. The fault current limiting performance of the FCL coil was evaluated through over-current tests using a capacitor bank. The FCL coil successfully suppressed a fault current of 10.4 kA to below 2.1 kA.
- Published
- 2008
32. First Experiment on Levitation and Plasma With HTS Magnet in the RT-1 Plasma Device
- Author
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S. Mizumaki, Nobuo Tachikawa, K. Nakamoto, Y. Ohtani, Yuichi Ogawa, M. Shibui, Zensho Yoshida, Junji Morikawa, Toru Kuriyama, Taizo Tosaka, and M. Ono
- Subjects
Physics ,Condensed matter physics ,business.industry ,Superconducting magnet ,Plasma ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,Electromagnetic coil ,Magnet ,Water cooling ,Levitation ,Optoelectronics ,Vacuum chamber ,Electrical and Electronic Engineering ,business ,Magnetic levitation - Abstract
The high temperature superconducting (HTS) floating magnet of the ring trap 1 (RT-1) reached the first experiment on levitation and plasma. The magnet using an HTS coil was levitated stably by levitation coil, and plasma was produced around the ring-shaped HTS magnet by electron cyclotron heating with 8.2 GHz microwave. This novel plasma device was constructed at the University of Tokyo to explore means of achieving the advanced-fuel fusion. The plasma confinement mechanism is based on the concept of high-beta relaxed state that is self-organized within flowing plasma. The HTS magnet is operated in a persistent-current mode and magnetically levitated in a plasma vacuum chamber. The weight of the HTS magnet is about 110 kg. Initially the HTS coil is cooled below 20 K by an external cooling system with detachable transfer tubes. After the transfer tubes are detached, an experiment of levitation and plasma is conducted while the HTS coil temperature remains within the range of 20 K-32 K without cooling. This paper describes the HTS coil design and test results of the HTS magnet as follows; an initial cooling, a persistent-current operation without cooling and the first levitation and the first plasma experiment.
- Published
- 2007
33. Quantitative Understanding of Scanning Spreading Resistance Microscopy with Schottky Contact Model
- Author
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T. Ishihara, S. Itai, M. Ono, K. Matsuzawa, and L. Zhang
- Subjects
Materials science ,Spreading resistance profiling ,business.industry ,Schottky barrier ,Microscopy ,Optoelectronics ,business - Published
- 2015
34. Design study of superconducting sextupole magnet using HTS coated conductor for neutron-focusing device
- Author
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Kei Koyanagi, Taizo Tosaka, Kiyosumi Tsuchiya, Hirohiko M. Shimizu, Jun-ichi Suzuki, M. Ono, I. Watanabe, Toshikazu Adachi, and Toru Kuriyama
- Subjects
Materials science ,Electropermanent magnet ,Condensed matter physics ,business.industry ,Aperture ,Energy Engineering and Power Technology ,Superconducting magnet ,Condensed Matter Physics ,Sextupole magnet ,Electronic, Optical and Magnetic Materials ,Ferromagnetism ,Dipole magnet ,Condensed Matter::Superconductivity ,Magnet ,Physics::Accelerator Physics ,Optoelectronics ,Electrical and Electronic Engineering ,business ,Electrical conductor - Abstract
We performed a design study of sextupole magnet using high temperature superconducting (HTS) wires. The sextupole magnet is used as a focusing lens for neutron-focusing devices. A neutron-focusing device is desired to have a large aperture and a high magnetic field gradient of G , where G = 2 B / r 2 , B is the magnetic field and r is a distance from the sextupole magnet axis. Superconducting magnets offer promising prospects to meet the demands of a neutron-focusing device. Recently NbTi coils of low temperature superconducting (LTS) have been developed for a sextupole magnet with a 46.8 mm aperture. The maximum magnetic field gradient G of this magnet is 9480 T/m 2 at 4.2 K and 12,800 T/m 2 at 1.8 K. On the other hand, rapid progress on second generation HTS wire has been made in increasing the performance of critical current and in demonstrating a long length. The second generation HTS wire is referred to as coated conductor. It consists of tape-shaped base upon which a thin coating of superconductor, usually YBCO, is deposited or grown. This paper describes a design study of sextupole magnet using coated conductors.
- Published
- 2006
35. Bone Lengthening in Children
- Author
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Valentin Antoci, Craig M. Ono, and Ellen M. Raney
- Subjects
Adult ,medicine.medical_specialty ,Contracture ,Adolescent ,medicine.medical_treatment ,Osteogenesis, Distraction ,Bone Nails ,Osteotomy ,Bone Lengthening ,medicine ,Humans ,Orthopedics and Sports Medicine ,Femur ,Tibia ,Child ,Retrospective Studies ,business.industry ,Biomechanics ,Retrospective cohort study ,General Medicine ,Biomechanical Phenomena ,Surgery ,Torque ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Distraction osteogenesis ,medicine.symptom ,business - Abstract
Purpose: Complications arising from limb-lengthening procedures are often severe leading to long-term residuals. The aim of this study was to determine whether the complication rate and complexity could be predicted using a distraction index for bone lengthening in children. Study Design: This study retrospectively reviewed a series of 116 lower limbs lengthening in 88 consecutive patients (mean age 13.5). Mean follow-up 3.8 years. Lengthening percentage, lengthening index, distraction regenerate length, additional surgeries, and complications rate were used to evaluate the results of limb lengthening. The correlation between lengthening percentage and complication rate was particularly analyzed and its practicability illustrated. Scatter plots of complication rate (%) against lengthening percentage were constructed, and linear regression was used to investigate mathematical relationship between the variables. Results: The lengthening index was 33 ± 12.1 days/cm. The length of distraction regenerate was 6 ± 3.2 cm. The lengthening percentage was 21 ± 16.5. The scatter plots of neurological complication rate, residual deformities rate, broken pins rate, joint contractures rate, and hypertension rate against lengthening percentage showed a positive linear relationship with r = 0.8. Conclusions: The number of complications increased considerably with the increase in lengthening percentage. The lengthening percentage correlates very well with the complication rate and can be used to predict the complication rate. Clinical Relevance: During planning a lengthening procedure, the lengthening percentage should be a useful tool to predict the complications rate and to discuss the risks and benefits with patients and their families. The knowledge about predictable complications should help prevent and early detect expected complications.
- Published
- 2006
36. Test Results of an Experimental Coil with Bi-2212 Rutherford Cable for High Energy-density HTS-SMES
- Author
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Shigeo Nagaya, M. Ono, S. Nomura, Kenji Tasaki, Taizo Tosaka, Kei Koyanagi, K. Shimada, N Hirano, Tsutomu Kurusu, K. Kidoguchi, Y. Ishii, K. Ohsemochi, and H. Onoda
- Subjects
History ,Rutherford cable ,Engineering ,Electromagnet ,business.industry ,Electrical engineering ,Mechanical engineering ,Superconducting magnetic energy storage ,Superconducting magnet ,Computer Science Applications ,Education ,law.invention ,Electromagnetic coil ,law ,Magnet ,Electrical equipment ,business ,Rogowski coil - Abstract
Since FY 2004, a four-year Japanese national project has been ongoing to develop an HTS-SMES as a sub-program of the Development of Superconducting Power Network Control Technology. The purpose of this project is to confirm the performance of a high energy density SMES coil with Bi-2212 cables. This coil system is composed of an NbTi outer coil and a Bi-2212 inner coil, consisting of 16 double pancakes. A Bi2212 cable of 140 m length is used for the double-pancake windings, and reinforcing materials are co-wound with the cable. A winding inner diameter of 360 mm was set according to the bending tolerance of the cable. The magnet is to be cooled at 4.2 K by liquid helium in order to obtain high overall current density. In the first year of this project, a conceptual design and various experiments for HTS magnet were carried out. This paper describes the test results of the HTS experimental coil that was developed to evaluate the electrical and thermal characteristics of an HTS. It is important to minimize deterioration and damage to the cable, because such defects cause fatal impact to the coil. Consequentially, high accuracy measurement of V-I characteristics up to10−8 V/cm range was performed in this experiment.
- Published
- 2006
37. A new design of SMES coil for bridging instantaneous voltage dips
- Author
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I Senda, M Ono, H Ogata, S. Nomura, T Tosaka, and T Kurusu
- Subjects
History ,Key point ,Engineering ,Bridging (networking) ,business.industry ,Electromagnetic coil ,Electrical engineering ,business ,Computer Science Applications ,Education ,Voltage - Abstract
This paper describes a new design concept of SMES coil for bridging instantaneous dips and some experimental results. The technical key point of this work is the design of a NbTi coil composed of a monolith NbTi/Cu wire for DC application. In order to cover the disadvantages of the monolith wire, some solutions have been proposed and tested using a fullscale test coil. Experimental results show the validity of the design concept of the SMES coil.
- Published
- 2006
38. Development of Persistent-Current Mode HTS Coil for the RT-1 Plasma Device
- Author
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Y. Ohtani, Toru Kuriyama, Taizo Tosaka, M. Ono, Zensho Yoshida, Nobuo Tachikawa, Junji Morikawa, S. Mizumaki, M. Shibui, Yuichi Ogawa, and K. Nakamoto
- Subjects
Cryostat ,Materials science ,business.industry ,Superconducting magnet ,Plasma ,Condensed Matter Physics ,Quantitative Biology::Genomics ,Electronic, Optical and Magnetic Materials ,Nuclear magnetic resonance ,Electromagnetic coil ,Condensed Matter::Superconductivity ,Magnet ,Water cooling ,Optoelectronics ,Tube (fluid conveyance) ,Electrical and Electronic Engineering ,business ,Electrical conductor - Abstract
The plasma confinement device "RT-1" which had a high temperature superconducting (HTS) floating magnet was constructed for advanced high-beta plasma and fusion research at the University of Tokyo. The high temperature superconducting (HTS) floating magnet is magnetically levitated inside the plasma vacuum vessel. Plasma is confined by a magnetic dipole field around the HTS floating magnet. The HTS floating magnet is operated in persistent-current mode and it consists of an HTS coil, an HTS persistent-current switch (PCS), a pair of demountable joints of current leads, detachable joints of a cooling tube, a thermal shield and a vacuum vessel. The HTS coil and the PCS and the thermal shield are cooled below 20 K by a flow of helium gas through the cooling tube. The floating HTS magnet is designed to operate in the temperature range from 20 K to 30 K without being cooled while it is levitated. We fabricated a persistent-current HTS coil that consists of the HTS coil and the PCS. Persistent-current operations and protection tests were conducted with the persistent-current HTS coil before it was mounted in the floating magnet cryostat. The current-decay rate was 0.9% in an 8 hour operation. The coil energy was safely discharged by inducing PCS quench in a protection test
- Published
- 2006
39. Japanese nurse practitioner practice and outcomes in a nursing home
- Author
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M. Tonai, J.K. Magilvy, Shinji Miyauchi, Sachiyo Murashima, K. Saiki, M. Ono, Y. Edzuki, and Hiromi Fukuda
- Subjects
District nurse ,Aged, 80 and over ,Male ,medicine.medical_specialty ,Surgical nursing ,business.industry ,Nurse practitioners ,Care provision ,Nurse's Role ,Nursing Homes ,Oncology nursing ,Nursing ,Geriatric Nursing ,Japan ,Family medicine ,Intervention (counseling) ,Outcome Assessment, Health Care ,medicine ,Humans ,Female ,Nurse Practitioners ,Nurse education ,business ,General Nursing ,Primary nursing - Abstract
Aim By describing the practice of a Japanese nurse practitioner, this descriptive case study discusses role development and outcomes before and after the intervention. Background One of the first Japanese nurse practitioners intervened at a nursing home during the government-designated trial period for nurse practitioner practice. Conclusion Because of the nurse practitioner's meticulous observation and timely care provision to the residents in collaboration with the physician and the other staff in the facility, comparative data showed improvement in daily health status management of every resident and decreased deterioration of residents' health conditions requiring ambulance transfer and hospitalization.
- Published
- 2014
40. Cryocooler-Cooled High<tex>$rm T_rm c$</tex>Superconducting Magnet Excited by a Hybrid Semiconductor-HTS Thermoelectric Element
- Author
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Tetsuji Okamura, A. Oguchi, M. Ono, and Toru Kuriyama
- Subjects
Materials science ,Condensed matter physics ,business.industry ,Cryogenics ,Superconducting magnet ,Cryocooler ,Condensed Matter Physics ,Thermoelectric materials ,Electronic, Optical and Magnetic Materials ,Condensed Matter::Materials Science ,Electromagnetic coil ,Condensed Matter::Superconductivity ,Magnet ,Thermoelectric effect ,Optoelectronics ,Electrical and Electronic Engineering ,business ,Extrinsic semiconductor - Abstract
This paper describes progress in a cryocooler-cooled HTS magnet excited by a thermo-electromotive force of a thermoelectric element. Since this system requires no external power sources, there are advantages in compactness and weight over conventional HTS magnet systems. Thus, it is suitable for applications in places where constraints on space and weight are severe. For improvement of this magnet system, we present a concept of the new thermoelectric element which consists of a thermoelectric semiconductor and a superconductor. This hybrid element passively utilizes a superconductor as a thermoelectric material and decreases the cryogenic heat leakage per unit current (Q/I) ideally by half. In this paper, experiments of an HTS coil excitation with a hybrid semiconductor-HTS thermoelectric element are reported. It is shown that there are some obvious merits in using the hybrid element as a substitute for a normal p- and n-type semiconductor element.
- Published
- 2005
41. Status and Plans for the National Spherical Torus Experimental Research Facility
- Author
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W. Heidbrink, Manfred Bitter, R. Marsala, Choong-Seock Chang, R.J. Akers, Kevin Tritz, J. R. Wilson, Luca Guazzotto, R.I. Pinsker, D. Mueller, Nobuhiro Nishino, J.M. Bialek, David R. Smith, I. Semenov, M. G. Bell, Brentley Stratton, M.J. Schaffer, T. Gibney, D. Pacella, C. Domier, B. LeBlanc, M. Kalish, J. Manickam, Fred Levinton, Vlad Soukhanovskii, Stanley Kaye, E. Perry, G. Rewoldt, S. Bernabei, T.S. Bigelow, L. Dudek, Hyeon K. Park, Thomas Jarboe, S. F. Paul, K. Shinohara, R. Feder, A. von Halle, P. Roney, K. W. Hill, S. G. Lee, J. Schmidt, G. Gettelfinger, David A Rasmussen, Yueng Kay Martin Peng, S. Ramakrishnan, Masayoshi Nagata, Yuichi Takase, E.D. Fredrickson, Mark D. Carter, K. C. Lee, S. J. Zweben, David W. Johnson, M. Ono, T. Peebles, J.R. Ferron, J. Lawson, John B Wilgen, Brian Nelson, M.M. Menon, G. Oliaro, E. Mazzucato, I. Zatz, D.S. Darrow, S. Krasheninnikov, C. Jun, Zhehui Wang, J. Robinson, C. K. Phillips, N.N. Gorelenkov, C. Neumeyer, P.M. Ryan, Alan H. Glasser, J. L. Lowrance, E. Ruskov, S. J. Diem, M. R. Wade, M. Williams, Xian-Zhu Tang, Osamu Mitarai, J. Timberlake, Xueqiao Xu, Tobin Munsat, D.W. Swain, G. A. Wurden, Rajesh Maingi, Clarisse Bourdelle, D. Mastravito, W. Zhu, A. R. Field, J.E. Menard, C. E. Kessel, C.E. Bush, Roger Raman, D.A. Gates, Dan Stutman, E. Fredd, M. H. Redi, J.C. Hosea, T. Stevenson, R. Kaita, D.A. Humphreys, W. R. Blanchard, Wayne A Houlberg, W. Davis, R.J. Maqueda, P. Sichta, D. P. Stotler, Ker-Chung Shaing, P. C. Efthimion, J. Chrzanowski, J. Boedo, R. Hatcher, R. Parsells, Guoyong Fu, Robert James Goldston, J. Foley, G.D. Porter, William R. Wampler, L.L. Lao, Abhay K. Ram, Aaron Sontag, N. C. Luhmann, T. M. Biewer, R. J. Hawryluk, Michael Finkenthal, C.H. Skinner, S. S. Medley, T. K. Mau, Jayhyun Kim, S.A. Sabbagh, Wonho Choe, L. R. Grisham, R. Woolley, Richard Ellis, G. Labik, E. J. Synakowski, S. Kubota, R. W. Harvey, G. Taylor, A. L. Roquemore, P. J. Heitzenroeder, Peter Beiersdorfer, R. E. Bell, A. Pigarov, H.W. Kugel, P.T. Bonoli, and H. Schneider
- Subjects
Engineering ,Tokamak ,business.industry ,Magnetic confinement fusion ,Context (language use) ,Torus ,Fusion power ,Experimental research ,law.invention ,law ,Component (UML) ,Beta (plasma physics) ,Systems engineering ,Electrical and Electronic Engineering ,business ,Simulation - Abstract
An overview of the research capabilities and the future plans on the MA-class National Spherical Torus Experiment (NSTX) at Princeton is presented. NSTX research is exploring the scientific benefits of modifying the field line structure from that in more conventional aspect ratio devices, such as the tokamak. The relevant scientific issues pursued on NSTX include energy confinement, MHD stability at high beta, non-inductive sustainment, solenoid-free start-up, and power and particle handling. In support of the NSTX research goal, research tools are being developed by the NSTX team. In the context of the fusion energy development path being formulated in the US, an ST-based Component Test Facility (CTF) and, ultimately a high beta Demo device based on the ST, are being considered. For these, it is essential to develop high performance (high beta and high confinement), steady-state (non-inductively driven) ST operational scenarios and an efficient solenoid-free start-up concept. We will also briefly describe the Next-Step-ST (NSST) device being designed to address these issues in fusion-relevant plasma conditions.
- Published
- 2005
42. Phase I trial of concurrent chemoradiotherapy with docetaxel, cisplatin and 5-fluorouracil (TPF) in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN)
- Author
-
T. Yoshida, M. Ono, Yasunori Sakuma, Satoshi Kawai, Yoichi Ikeda, S. Hirose, Izumi Mochimatu, Hideki Matsuda, Mamoru Tsukuda, Takahide Taguchi, Yasukazu Mikami, Junichi Ishitoya, Hideaki Katori, Yuji Tanigaki, K Yamamoto, and Chouichi Horiuchi
- Subjects
Oncology ,Male ,Cancer Research ,medicine.medical_specialty ,Maximum Tolerated Dose ,medicine.medical_treatment ,cisplatin ,chemoradiotherapy ,Clinical ,Leukocytopenia ,Internal medicine ,squamous cell carcinoma of the head and neck (SCCHN) ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Mucositis ,docetaxel ,Humans ,5-fluorouracil ,Infusions, Intravenous ,Aged ,Chemotherapy ,business.industry ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Surgery ,Regimen ,Treatment Outcome ,Epidermoid carcinoma ,Docetaxel ,Fluorouracil ,Head and Neck Neoplasms ,Carcinoma, Squamous Cell ,Female ,Taxoids ,business ,Chemoradiotherapy ,medicine.drug - Abstract
The aim of this study was to evaluate the efficacy and toxicity of a concurrent chemoradiotherapy using docetaxel, cisplatin and 5-fluorouracil (5-FU) (TPF) in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). In total, 19 patients with previously untreated stage III-IV SCCHN were entered onto this trial. Patients received two cycles of chemotherapy. Cycles were repeated every 4 weeks. The starting doses (dose level 1) were docetaxel 60 mg m(-2), cisplatin 70 mg m(-2), and 5-day continuous infusion of 5-FU 600 mg m(-2) day(-1). Radiation was targeted to begin on the first day of chemotherapy, day 1. The total radiation dose to the primary tumour site and neck lymph nodes was between 63.0 and 74.0 Gy. At least three patients were examined at each dose level before advancing to the next level. The maximum-tolerated dose (MTD) of this regimen was docetaxel 60 mg m(-2), cisplatin 60 mg m(-2) and 5-FU 600 mg m(-2) day(-1). The main toxicities were mucositis (grade 3 and 4, 79%), leukocytopenia (grade 3 and 4, 53%), neutropenia (grade 3 and 4, 42%), anaemia (grade 3, 16%), liver dysfunction (grade 3, 11%) and renal dysfunction (grade 2, 11%). The overall response rate was 100%, including 84% complete responses (CRs). This concurrent chemoradiotherapy with TPF was safe and well tolerated. The high CR rate justifies further evaluation of this chemoradiotherapy modality in advanced SCCHN patients.
- Published
- 2004
43. Influences of Structure Around Gate-Edge on High Electric Field Strength in MISFETsWith High->tex<$k$>/tex<Gate Dielectrics
- Author
-
M. Ono and A. Nishiyama
- Subjects
Materials science ,business.industry ,Gate dielectric ,Electrical engineering ,Time-dependent gate oxide breakdown ,Dielectric ,Electronic, Optical and Magnetic Materials ,Computer Science::Hardware Architecture ,Computer Science::Emerging Technologies ,Gate oxide ,Electric field ,Optoelectronics ,Electrical and Electronic Engineering ,Metal gate ,business ,MISFET ,High-κ dielectric - Abstract
In this paper, dependences of electric field strength around gate-edge in gate dielectrics of MISFETs with high-k gate dielectrics on design parameters are studied. It is newly found that locations of sidewall/gate dielectric interfaces relative to gate electrode edges are critical to electric field strength of high-k MISFETs. Electric field can be as high as 4 MV/cm, which could have large influences on the yield of large scale integrated circuits (LSIs) with high-k gate dielectrics. An explanation of this phenomenon is given by considering discontinuity in electric field at interfaces between two materials with different dielectric constants. It is clarified that an electrical potential of side and top surfaces of gate dielectrics is strongly affected by the discontinuity of electric field strength at interfaces. As a result, electric field strength around gate electrode edges critically depends on locations of sidewall/gate dielectrics interfaces relative to gate electrode edges. Based on the physical considerations, a structure, in which gate sidewalls are also made of high-k materials, is studied from the viewpoint of electric field strength around gate electrode edges. It is shown that this structure effectively suppresses electric field strength around gate edges.
- Published
- 2004
44. Prognostic factors in resection of pulmonary metastasis from colorectal cancer
- Author
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M. Ono, Masaaki Ito, K Nagai, I. Watanabe, Norio Saito, T. Arai, K Kawashima, and Masanori Sugito
- Subjects
Adult ,Male ,medicine.medical_specialty ,Lung Neoplasms ,Lymphovascular invasion ,Colorectal cancer ,medicine.medical_treatment ,Gastroenterology ,Metastasis ,Risk Factors ,Internal medicine ,medicine ,Humans ,Stage (cooking) ,Survival analysis ,Aged ,Retrospective Studies ,Lung ,business.industry ,Respiratory disease ,Middle Aged ,Prognosis ,medicine.disease ,Survival Analysis ,Surgery ,medicine.anatomical_structure ,Lymphatic Metastasis ,Female ,Hepatectomy ,Colorectal Neoplasms ,business - Abstract
Background The aim of this retrospective study was to evaluate characteristics of primary colorectal cancer and pulmonary metastases in order to identify prognostic factors for overall survival and risk factors for further intrapulmonary recurrence after resection of pulmonary metastases from colorectal cancer. Methods Forty-nine patients who underwent resection of pulmonary metastases from colorectal cancer were reviewed. The factors assessed were age, sex, pathological findings of the original colorectal cancer (depth, lymphatic invasion, venous invasion, lymph node metastasis, differentiation, Dukes' stage) and pulmonary metastasis (maximum tumour size, number of tumours, completeness of resection), serum carcinoembryonic antigen level, previous hepatectomy for liver metastases, and surgical procedure for resection of pulmonary metastasis. Overall survival and intrapulmonary recurrence were also reviewed. Results Survival rates after resection of pulmonary metastases were 78 per cent at 3 years and 56 per cent at 5 years. Solitary pulmonary metastases were significantly correlated with survival (P = 0·049). The pathological features of the primary colorectal cancer had no impact on survival. Histologically incomplete resection of pulmonary metastasis significantly correlated with pulmonary re-recurrence (P = 0·034). Conclusion Long-term survival can be expected after complete resection of pulmonary metastases arising from colorectal cancer, especially in patients with a solitary pulmonary metastasis.
- Published
- 2003
45. Fate of Pesticide Metabolites on Malt during Brewing
- Author
-
M. Ono, R. Tajima, and Y. Miyake
- Subjects
0106 biological sciences ,Chromatography ,Pesticide residue ,business.industry ,Metabolite ,technology, industry, and agriculture ,food and beverages ,04 agricultural and veterinary sciences ,Pesticide ,040401 food science ,01 natural sciences ,Applied Microbiology and Biotechnology ,chemistry.chemical_compound ,0404 agricultural biotechnology ,Triadimefon ,chemistry ,010608 biotechnology ,behavior and behavior mechanisms ,Brewing ,Food science ,business ,Food Science ,Biotechnology - Abstract
The fate of fungicidally active metabolites of triadimefon and triflumizole during brewing was studied to estimate their risk of carryover into beer. The water-solubilities of these metabolites, de...
- Published
- 2003
46. Quantitative Assessment of Harmonic Power Doppler Myocardial Perfusion Imaging with Intravenous LevovistTM in Patients with Myocardial Infarction: Comparison with Myocardial Viability Evaluated by Thallium-201 Single-Photon Emission Computed Tomography and Coronary Flow Reserve
- Author
-
T. Tani, Koichi Tamita, S. Mizoguchi, Kazuaki Tanabe, M. Ono, Toshikazu Yagi, Minako Katayama, Takamitsu Takagi, Kenichi Shiratori, Shigefumi Morioka, Kenji Yamabe, M. Ibuki, K. Nagai, and Atsushi Yamamuro
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Coronary flow reserve ,General Medicine ,Blood flow ,Single-photon emission computed tomography ,Doppler echocardiography ,medicine.disease ,Myocardial perfusion imaging ,Coronary circulation ,medicine.anatomical_structure ,Internal medicine ,medicine ,Cardiology ,Radiology, Nuclear Medicine and imaging ,Myocardial infarction ,Cardiology and Cardiovascular Medicine ,business ,Emission computed tomography - Abstract
Background: Intravenous myocardial contrast echocardiography with harmonic power Doppler imaging is a novel technique for assessing myocardial perfusion. Aims: The aim of this study was to quantitatively assess myocardial perfusion by harmonic power Doppler imaging in patients with a previous myocardial infarction and compare myocardial contrast echocardiography results with myocardial viability evaluated by thallium-201 single-photon emission computed tomography (201Tl-SPECT) and the results of Doppler flow measurement of coronary flow velocity reserve. Methods: Twenty-three patients with anterior myocardial infarction who were scheduled for adenosine stress 201Tl-SPECT underwent myocardial contrast echocardiography with harmonic power Doppler imaging. Harmonic power Doppler imaging was performed at rest and during adenosine infusion (0·15 mg/kg/min) using an intravenous infusion of Levovist. The peak colour pixel intensity ratios of the risk area to the control area were used for quantitative analysis of myocardial perfusion by harmonic power Doppler imaging. Coronary blood flow velocity was measured using Doppler-tipped guidewire in the distal portion of left anterior descending artery and coronary flow velocity reserve was calculated. Results: In patients with myocardial viability assessed by 201Tl-SPECT, pixel intensity ratios both at rest and during hyperaemia were significantly higher compared with those in patients without myocardial viability (at rest: 0·62±0·28 vs 0·37±0·17, P =0·038, during hyperaemia 0·72±0·19 vs 0·40±0·18, P =0.003). Coronary flow velocity reserve was significantly different between two groups (2·35±0·43 vs 1·49±0·53, P
- Published
- 2002
47. Japan's superconducting Maglev train
- Author
-
M. Ono, H. Ohtsuki, and S. Koga
- Subjects
Engineering ,business.industry ,Superconducting magnet ,Linear motor ,Propulsion ,Automotive engineering ,law.invention ,Test line ,Electromagnetic coil ,law ,Maglev ,Electrical and Electronic Engineering ,business ,Instrumentation ,Magnetic levitation ,Armature (electrical engineering) - Abstract
We have developed a Maglev train under the guidance of the Japanese Ministry of Transport. The Maglev train is an advanced train that can run more than 500 km/h with a linear synchronous motor (LSM) that has both a superconducting magnet on board and an armature coil in the ground. The Maglev train was tested on the Yamanashi Maglev test line. Tests began in 1997, which exercised various functions of performance. The main results of the tests are reported in this article.
- Published
- 2002
48. Development of a superconducting magnet excited with thermoelectric conversion element for quasi persistent mode
- Author
-
Toru Kuriyama and M. Ono
- Subjects
Flux pumping ,Materials science ,business.industry ,Superconducting electric machine ,Superconducting magnetic energy storage ,Superconducting magnet ,Condensed Matter Physics ,Magnetic flux ,Electronic, Optical and Magnetic Materials ,law.invention ,Nuclear magnetic resonance ,law ,Condensed Matter::Superconductivity ,Magnet ,Optoelectronics ,Electrical and Electronic Engineering ,business ,Low voltage ,Excitation - Abstract
Some superconducting magnets are generally operated in persistent mode. The persistent-mode operation of these magnets is necessary to maintain field decay rates below a certain level, typically 0.01 ppm over a 1-hr period. These magnets used to be physically uncoupled from the external power source. In the case of HTS magnets, it is very difficult to keep the magnetic field stable without a high-stability external power source for large flux flow losses. A superconducting magnet is a high current and low voltage system except for excitation voltage. From this point of view, a thermoelectric conversion element is a very suitable power supply for a quasi persistent-mode magnet system. Moreover, this element seems to be particularly useful for HTS magnets. As the first step of this study, the authors tried to design a superconducting magnet excited with a thermoelectric conversion element and carried out an excitation test of a small HTS magnet by using the elements.
- Published
- 2002
49. Nizatidine and cisapride enhance salivary secretion in humans
- Author
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M. Ono, Akira Kawamura, Yoshikazu Kinoshita, Hirofumi Fujishiro, Mika Yuki, and Kyoichi Adachi
- Subjects
Saliva ,medicine.medical_specialty ,Hepatology ,business.industry ,Bicarbonate ,Gastroenterology ,Stimulation ,Famotidine ,chemistry.chemical_compound ,Endocrinology ,chemistry ,Epidermal growth factor ,Cisapride ,Internal medicine ,medicine ,Cholinergic ,Pharmacology (medical) ,business ,Nizatidine ,medicine.drug - Abstract
Background: Salivation plays an important role in the defence of the oesophageal mucosa against gastric acidic reflux and can be evoked by cholinergic stimulation. Both nizatidine and cisapride have been reported to increase acetylcholine concentrations in the cholinergic system. Aim: To investigate the effect of nizatidine and cisapride on salivary secretion, salivary epidermal growth factor and bicarbonate output. Methods: The salivary volume and concentration of salivary epidermal growth factor and bicarbonate were measured after the administration of nizatidine (150 mg), famotidine (20 mg) and cisapride (5 mg) in 30 male healthy volunteers. Results: Basal and stimulated salivary secretions were found to be increased after the administration of nizatidine and cisapride. In contrast, salivary secretion was not increased by famotidine. Although epidermal growth factor content was not augmented, nizatidine and cisapride administration also increased the bicarbonate output in mastication-stimulated saliva. Conclusions: Increased salivary secretion and bicarbonate output induced by nizatidine may be useful for the treatment of patients with gastro-oesophageal reflux disease.
- Published
- 2002
50. A Case of Metastasis to the Uterine Corpus from Rectal Cancer Showing Diagnostic Usefulness of the FDG-PET Scan
- Author
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I. Watanabe, M. Ishii, K. Kawashima, Norio Saito, S. Ohmori, C. Kosugi, Masanori Sugito, M. Ono, and Masaaki Ito
- Subjects
medicine.medical_specialty ,business.industry ,Colorectal cancer ,Uterine corpus ,Gastroenterology ,Medicine ,Surgery ,Radiology ,business ,medicine.disease ,Metastasis - Abstract
女性生殖器以外の腫瘍を原発巣とする転移性子宮腫瘍は頻度が少なく,また大腸癌からの転移は極めて稀である.我々は直腸癌の腹腔内再発及び子宮体部転移をきたした症例を経験したので報告する.患者は3年前に直腸癌の切除を受けており,術後経過観察中に血清CEA値の上昇を認めた.MRI,CTにて子宮体部に腫瘍を認め,術前のFDG-PETにて直腸癌からの子宮体部転移と判断した.切除標本の病理組織検査では中分化腺癌を認め直腸癌の子宮体部転移と考えた.転移性子宮腫瘍に対しては確立した診断法は無く,また転移性子宮腫瘍の患者は診断の時点で他臓器の転移があることが多い.転移性子宮腫瘍に対して手術を行う前に他臓器への転移の有無を確認することが重要であろう.本症例では転移性子宮腫瘍の診断と他臓器の遠隔転移の除外においてFDG-PETが有用であった.
- Published
- 2002
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