11 results on '"Jooyoung Jung"'
Search Results
2. Effects of Grid Characteristics on High Speed Circuit Breaker for Railway Vehicle
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Jooyoung Jung, Jinnil Choi, and Ji-Won Park
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010302 applied physics ,Engineering ,business.industry ,Strategy and Management ,020208 electrical & electronic engineering ,Geography, Planning and Development ,Electrical engineering ,Energy Engineering and Power Technology ,Transportation ,02 engineering and technology ,Grid ,01 natural sciences ,0103 physical sciences ,Automotive Engineering ,0202 electrical engineering, electronic engineering, information engineering ,business ,Circuit breaker ,Civil and Structural Engineering - Published
- 2016
3. Voluntary Movements as a Possible Non-Reflexive Pain Assay
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Hawon Cho, Uhtaek Oh, Byeongjun Lee, Hyeyoun Chun, Sun Wook Hwang, Jooyoung Jung, Yongwoo Jang, and Sung Min Kim
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Male ,medicine.medical_specialty ,Neurology ,Rearing ,Inflammatory pain ,Total distance moved ,Pain medicine ,Voluntary movement ,Pain ,TRPV Cation Channels ,Mice, Inbred Strains ,Motor Activity ,Neuropathic pain ,Carrageenan ,Mice ,Cellular and Molecular Neuroscience ,Pain assessment ,medicine ,Animals ,Pain Measurement ,Inflammation ,Analgesics ,Hypoalgesia ,business.industry ,Research ,Anti-Inflammatory Agents, Non-Steroidal ,Visceral pain ,TRPV1 ,medicine.disease ,Rats ,Disease Models, Animal ,Anesthesiology and Pain Medicine ,Anesthesia ,Morphine ,Neuralgia ,Molecular Medicine ,medicine.symptom ,business ,medicine.drug - Abstract
Background The quantification of pain intensity in vivo is essential for identifying the mechanisms of various types of pain or for evaluating the effects of different analgesics. A variety of behavioral tests for pain measurement have been devised, but many are limited because animals are physically restricted, which affects pain sensation. In this study, pain assessment was attempted with minimal physical restriction, and voluntary movements of unrestrained animals were used to evaluate the intensities of various types of pain. Results The number of times animals reared or total distances traveled was measured using a motion-tracking device and found to be markedly reduced in carrageenan-induced inflammatory, acetic acid-induced visceral, and streptozotocin-induced neuropathic pain tests. These two voluntary movement parameters were found to be highly correlated with paw withdrawal latency from irradiating heat. In addition, these parameters were markedly reversed by morphine and by non-steroidal anti-inflammatory drugs in inflammatory pain models. These parameters were also useful to detect hypoalgesia in TRPV1−/− mice. Conclusions These results suggest that parameters of voluntary movement, such as, number of rearing and total distance moved, are effective indicators of pain intensity for many types of pain and that they can be used to evaluate degree of pain perception.
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- 2013
4. Comparison of Intrathecal Chemotherapy for Leptomeningeal Carcinomatosis of a Solid Tumor: Methotrexate Alone Versus Methotrexate in Combination with Cytosine Arabinoside and Hydrocortisone
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Dae-Young Kim, Tae-You Kim, Yung-Jue Bang, Noe Kyeong Kim, Dong Wan Kim, Tak Yun, Keun Wook Lee, Dae Seog Heo, Jooyoung Jung, and Sook Ryun Park
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Adult ,Male ,Oncology ,Cancer Research ,medicine.medical_specialty ,Adolescent ,Hydrocortisone ,Adenocarcinoma ,Gastroenterology ,Drug Administration Schedule ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,Meningeal Neoplasms ,medicine ,Carcinoma ,Humans ,Radiology, Nuclear Medicine and imaging ,Carcinoma, Small Cell ,Survival rate ,Injections, Spinal ,Aged ,Retrospective Studies ,business.industry ,Stomach ,Cytarabine ,General Medicine ,Middle Aged ,medicine.disease ,Chemotherapy regimen ,Survival Rate ,Methotrexate ,medicine.anatomical_structure ,Female ,business ,medicine.drug - Abstract
To compare the efficacy of intrathecal methotrexate single therapy with three-drug combination therapy in patients with leptomeningeal carcinomatosis.Fifty-five patients who had pathologically proven leptomeningeal carcinomatosis of a solid tumor were evaluated in terms of pathological response. Group M (n = 29) received methotrexate 15 mg and group MHA (n = 26) received methotrexate 15 mg, hydrocortisone 15 mg/m(2) and ara-C 30 mg/m(2) twice a week intrathecally until a cytological response was obtained.Primary sites of the tumor were the lung (n = 33), breast (n = 13) and stomach (n = 5). The pathology of 45 patients was adenocarcinoma. The cytological response rate to intrathecal chemotherapy was significantly higher in the MHA group than in the M group (38.5 vs 13.8%, P = 0.036). The median survival was 18.6 weeks in the MHA arm and 10.4 weeks in the M arm (P = 0.029).Combination intrathecal chemotherapy with methotrexate, cytosine arabinoside and hydrocortisone showed more favorable effects than methotrexate single therapy for leptomeningeal carcinomatosis in solid tumors.
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- 2003
5. Airway Obstruction after Acute Ozone Exposure in BALB/c Mice Using Barometric Plethysmography
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Chung Ho Yeum, An Soo Jang, Jooyoung Jung, Sun Wook Kim, Byung-Cheol Song, and Inseon S. Choi
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Ozone ,Risk Assessment ,Sensitivity and Specificity ,Statistics, Nonparametric ,Time ,BALB/c ,Mice ,chemistry.chemical_compound ,Reference Values ,Animals ,Medicine ,Plethysmograph ,Ozone exposure ,Plethysmography, Whole Body ,Probability ,Mice, Inbred BALB C ,Enhanced Pause ,biology ,Inhalation ,business.industry ,Sulfuric Acids ,respiratory system ,Airway obstruction ,biology.organism_classification ,medicine.disease ,Respiratory Function Tests ,respiratory tract diseases ,Airway Obstruction ,Disease Models, Animal ,Animals, Newborn ,chemistry ,Anesthesia ,Female ,Original Article ,business ,Bronchoalveolar Lavage Fluid ,Airway responsiveness - Abstract
Background Airway responsiveness after acute inhalation of ozone is related to the concentration and duration of ozone exposure. Using barometric whole-body plethysmography and increase in enhanced pause (Penh) as an index of airway obstruction, we measured the response of BALB/c mice to acute ozone inhalation to study the time course change of pulmonary function after ozone exposure. Methods Penh was measured before and after exposure to filtered air or 0.12, 0.5, 1, or 2 ppm ozone for 3 hr (n=6/group). In addition, Penh was measured 24, 48 and 72 hr after ozone exposure. Bronchoalveolar lavage (BAL) and histopathologic examinations were performed. Results The increase in Penh after ozone exposure was significantly higher in the 0.12, 0.5, 1 and 2 ppm groups compared with the control group (all p
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- 2003
6. Fast subpel motion estimation using selective motion vector accuracy of inter-mode decision for H.264/AVC
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Byeungwoo Jeon, Yong-Serk Kim, Bongsoo Jung, Woong Choi, Jooyoung Jung, and Dae-Sung Cho
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Motion compensation ,business.industry ,Computer science ,Motion estimation ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Computer vision ,Artificial intelligence ,business ,Motion vector ,Transform coding ,Quarter-pixel motion - Abstract
MPEG-4 Part-10 AVC/H.264 (H.264/AVC) is the newest video coding standard developed and finalized in March 2003 by the Joint Video Team (JVT) of ISO/IEC (MPEG) and ITU-T (VCEG). It includes many powerful features such as multiple reference pictures, variable block-size motion compensation, quarter-pel accuracy motion compensation, and so on. As a result, it achieves high coding performance but at the expense of huge computational complexity. To reduce the complexity while keeping the same coding performance, we propose a low complexity subpel motion estimation method using two content-aware decision criteria. Based on the criteria, four different levels of subpel motion estimation are proposed to achieve low complexity subpel motion estimation. Simulation results show that the proposed method reduces total encoding time by 55.53% on average and subpel motion estimation time by 82.2% on average.
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- 2009
7. Non-small cell lung cancer initially presenting with intracardiac metastasis
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Sang Ik Hwang, Chull Sung Jung, Sang Hak Lee, Young Iee Park, Jung Han Kim, Jooyoung Jung, and Chong Woo Yoo
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Male ,medicine.medical_specialty ,Pathology ,Lung Neoplasms ,Heart Ventricles ,Case Report ,Malignancy ,Intracardiac injection ,Metastasis ,Heart Neoplasms ,Carcinoma, Non-Small-Cell Lung ,Carcinoma ,Medicine ,Humans ,cardiovascular diseases ,Lung cancer ,Lymph node ,Cardiac metastasis ,Lung ,business.industry ,Middle Aged ,medicine.disease ,medicine.anatomical_structure ,PET ,Ventricle ,cardiovascular system ,Radiology ,business - Abstract
Intracardiac metastasis as the initial presentation of malignant neoplasm is very rare. We report here on a 64-year-old man with non-small cell lung cancer (NSCLC) initially presenting with intracardiac metastasis which was identified with 18-F fluorodeoxyglucose positron emission tomography (FDG PET). The patient was admitted with complaints of exertional dyspnea and vague chest discomfort that had developed a few weeks ago. Two-dimensional echocardiography revealed a heart mass attached to its akinetic wall in the right ventricular chamber. CT and MRI demonstrated a large tumor involving the epicardium and myocardium in the right ventricle, and there was a mass in the right lower lobe of the lung along with multiple lymphadenopathies. Cytologic examination of the percutaneous needle aspiration of a lymph node in the anterior mediastinum revealed malignant epithelial cell nests, and this was strongly suggestive of squamous cell carcinoma. Subsequent FDG PET confirmed that the intracardiac mass had an abnormally increased FDG uptake, and again this was strongly suggestive of malignancy. By systemically considering these imaging studies, we were able to diagnose the mass as intracardiac metastasis of NSCLC.
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- 2005
8. Induction chemotherapy followed by radiotherapy in the treatment of anal cancer
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Noe Kyeong Kim, Dae Ho Lee, Sung Whan Ha, Jooyoung Jung, Inho Kim, Keun Wook Lee, Dae-Young Kim, Hun Ho Song, Jae-Gahb Park, Tae-You Kim, Dae Seog Heo, and Yung-Jue Bang
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Adult ,Male ,Cancer Research ,medicine.medical_specialty ,medicine.drug_class ,Mitomycin ,medicine.medical_treatment ,Antimetabolite ,Cohort Studies ,Antineoplastic Combined Chemotherapy Protocols ,Humans ,Medicine ,Anal cancer ,Survival rate ,Aged ,Neoplasm Staging ,Retrospective Studies ,Chemotherapy ,business.industry ,Remission Induction ,Cancer ,Induction chemotherapy ,General Medicine ,Middle Aged ,Anus Neoplasms ,medicine.disease ,Combined Modality Therapy ,Surgery ,Survival Rate ,Radiation therapy ,Oncology ,Fluorouracil ,Carcinoma, Squamous Cell ,Female ,Cisplatin ,business ,Follow-Up Studies ,medicine.drug - Abstract
This study was conducted to investigate the efficacy of the induction chemotherapy followed by radiotherapy in anal cancer. Twenty-three patients diagnosed with anal cancer between March 1991 and February 1999 were treated with induction chemotherapy with 5-fluorouracil based regimens followed by external beam radiation. After a median follow-up of 78 months, the overall survival and the disease-free survival at 5 years was 71.3 and 67.5%, respectively. The colostomy-free survival at 5 years was 91%, as the inguinal lymph nodes were the most frequent site of relapse. Serious side effects did not occur and late complications did not develop either. Induction chemotherapy followed by radiotherapy in patients with anal cancer is effective in terms of its response and preserving the anal sphincter without serious acute and late complications.
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- 2003
9. An Adult with Aplastic Crisis induced by Human Parvovirus B19 as an Initial Presentation of Hereditary Spherocytosis
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Jung Han Kim, Kwang Hyuk Park, Chi Hun Choi, Min Jeong Park, Sook Eui Oh, Jooyoung Jung, and Young Lee Park
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Adult ,Anemia ,viruses ,Aplastic crisis ,Spherocytosis ,Case Report ,Spherocytosis, Hereditary ,Hereditary spherocytosis ,Parvoviridae Infections ,hemic and lymphatic diseases ,Parvovirus B19, Human ,medicine ,Humans ,Reticulocytopenia ,Parvovirus B 19 ,business.industry ,Anemia, Aplastic ,virus diseases ,medicine.disease ,Pancytopenia ,Sickle cell anemia ,medicine.anatomical_structure ,Immunology ,Female ,Bone marrow ,Packed red blood cells ,business ,Pancyopenia - Abstract
The association between aplastic crisis and human parvovirus (HPV) B19 infection is well described in patients with sickle cell anemia. This association has also been described, although much less frequently, in patients with hereditary spherocytosis (HS). However, most cases of aplastic crises in patients with HS and induced by HPV B19 have been reported in children or adolescents. In this paper, we describe an aplastic crisis induced by HPV B19 in an adult with HS. A 34-year-old female presented with presyncope, febrile sensation, and myalgia. The complete blood counts showed severe anemia. The peripheral blood smear revealed spherocytosis with reticulocytopenia and pancytopenia. The direct Coombs' test was negative; the osmotic fragility test was positive. In the bone marrow aspirates, a few giant pronormoblasts with deep blue cytoplasm, pseudopods, and intracellular inclusion bodies were observed. The patient was given eight units of packed red blood cells. HPV B19 infection was proven by the presence of IgM antibodies to HPV B19 and the detection of viral DNA using the PCR technique. To the best of our knowledge, this is the first report in Korea that describes an adult with aplastic crisis presenting initially with HS.
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- 2005
10. A Case of Acute Mediastinitis Associated with Fish Bone with Successful Conservative Treatment
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Byung-Cheol Song, Hong Sup Lee, Jooyoung Jung, Guk Myung Choi, Sun Wook Kim, Jin Su Hwang, Kyung Mook Kim, Chung Ho Yeum, and An Soo Jang
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,business.industry ,Optimal treatment ,medicine.disease ,Mediastinitis ,Surgery ,Conservative treatment ,Infectious Diseases ,Swallowing ,medicine ,Severe morbidity ,business ,Intensive care medicine ,Order perciformes ,Acute mediastinitis ,Fish bone - Abstract
Acute mediastinitis is a life threatening disorder that causes severe morbidity in affected patient. We experienced a case of acute mediastinitis in a 56 year-old man as a result of swallowing a fish bone (order Perciformes, Family Pomacentridae). Conservative treatment, including starvation therapy and the injection of antibiotic drugs, were successful in treating this patient. Although the optimal treatment for acute mediastinitis remains controversial, it is important to choose the appropriate strategies when encountering cases of acute mediastinitis.
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- 2002
11. Anoctamin 1 Contributes to Inflammatory and Nerve-Injury Induced Hypersensitivity
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Young Duk Yang, Uhtaek Oh, Dong-Jin Yang, Byeongjun Lee, Jooyoung Jung, and Hawon Cho
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Nociception ,Inflammatory pain ,ANO1 ,Inflammation ,Bradykinin ,Neuropathic pain ,Cellular and Molecular Neuroscience ,Mice ,Chloride Channels ,Formaldehyde ,medicine ,Noxious stimulus ,Hypersensitivity ,Animals ,RNA, Messenger ,DRG neuron ,Anoctamin-1 ,Mice, Knockout ,biology ,business.industry ,Research ,Rheobase ,Nerve injury ,Sciatic Nerve ,Allodynia ,Anesthesiology and Pain Medicine ,Gene Expression Regulation ,nervous system ,Hyperalgesia ,Organ Specificity ,Anesthesia ,biology.protein ,Molecular Medicine ,medicine.symptom ,business ,Neuroscience - Abstract
Background Various pathological conditions such as inflammation or injury can evoke pain hypersensitivity. That represents the response to innocuous stimuli or exaggerated response to noxious stimuli. The molecular mechanism based on the pain hypersensitivity is associated with changes in many of ion channels in dorsal-root ganglion (DRG) neurons. Anoctamin 1 (ANO1/TMEM16A), a Ca2+ activated chloride channel is highly visible in small DRG neurons and responds to heat. Mice with an abolished function of ANO1 in DRG neurons demonstrated attenuated pain-like behaviors when exposed to noxious heat, suggesting a role in acute thermal nociception. In this study, we further examined the function of ANO1 in mediating inflammation- or injury-induced hyperalgesia or allodynia. Results Using Advillin/Ano1 fl/fl (Adv/Ano1 fl/fl ) mice that have a functional ablation of Ano1 mainly in DRG neurons, we were able to determine its role in mediating thermal hyperalgesia and mechanical allodynia induced by inflammation or nerve injury. The thermal hyperalgesia and mechanical allodynia induced by carrageenan injection and spared-nerve injury were significantly reduced in Adv/Ano1 fl/fl mice. In addition, flinching or licking behavior after bradykinin or formalin injection was also significantly reduced in Adv/Ano1 fl/fl mice. Since pathological conditions augment nociceptive behaviors, we expected ANO1′s contribution to the excitability of DRG neurons. Indeed, the application of inflammatory mediators reduced the threshold for action potential (rheobase) or time for induction of the first action potential in DRG neurons isolated from control (Ano1 fl/fl ) mice. These parameters for neuronal excitability induced by inflammatory mediators were not changed in Adv/Ano1 fl/fl mice, suggesting an active contribution of ANO1 in augmenting the neuronal excitability. Conclusions In addition to ANO1's role in mediating acute thermal pain as a heat sensor, ANO1 is also capable of augmenting the excitability of DRG neurons under inflammatory or neuropathic conditions and thereby aggravates inflammation- or tissue injury-induced pathological pain.
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