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Rationale: Sjogren's syndrome(SS) is a chronic autoimmune disease, which damages exocrine glands especially salivary and lacrimal glands, with xerostomia and xerophthalmia as common symptoms. Patient concerns: We report a case of a 49-year-old woman presented with pancytopenia. Her laboratory examinations lead us diagnose her as Sjogren's syndrome complicating pancytopenia. She had neurological symptoms during her treatment, which represent only 4.5% of Sjogren's syndrome complicating damage in nervous system. Diagnoses: Sjogren's syndrome complicating pancytopenia. Interventions: Dexamethasone (40mg QD for 4 days) and immunoglobulin (25g QD for 2 days) were administered for intensive treatment followed by oral methylprednisolone 40mg QD as maintenance treatment. Total glucosides of paeony 0.6g TID and danazol 0.2g BID per os were given. We also gave her Piperacillin-tazobactam and moxifloxacin for anti-infection and Fluconazole for anti-fungal therapy, as well as other supportive treatments. Outcomes: Follow-up of the patient observed the normalization of peripheral blood cell count, immunity indices and neurological examinations 6 months after discharge. Lessons: For patients presented with blood system abnormalities unilineage or multiple-lineage cytopenia in particular, history investigations and relevant examinations should be considered to exclude the existence of autoimmune diseases like Sjogren's syndrome.

In this paper, researches have been carried out on how to improve microprocessor system reliability using fault tolerant theory and technique. A kind of three module redundant fault-tolerant microprocessor system structure has been proposed which can mask both transient fault and permanent fault. This fault-tolerant system has been realized in hardware using microcontroller 80c552 as core. The fault-tolerant system consists of three functional modules with the same hardware and a fault-masking network. The three modules are alternative in function and the fault-masking network is used for fault-detection and fault-tolerance. The fault-tolerant microprocessor system has been applied in robotization automatic drilling machine and as the main control unit which executes key tasks. Its powerful fault-tolerance and high reliability have been proved by practice.