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Your search keyword '"Gosego Masasa"' showing total 3 results
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3 results on '"Gosego Masasa"'

1. A Counseling and Monitoring Approach for Supporting Breastfeeding Women Living With HIV in Botswana

Author

Gosego Masasa, Mompati Mmalane, Justine Legbedze, Lena J. Volpe, Jennifer Jao, Nicholas K. Mmasa, Joseph Makhema, Shan Sun, Samuel Kgole, Elaine J. Abrams, and Kathleen M. Powis

Subjects
Counseling, medicine.medical_specialty, Botswana, business.industry, Breastfeeding, Human immunodeficiency virus (HIV), HIV Infections, medicine.disease_cause, Infectious Disease Transmission, Vertical, Article, Infectious Diseases, Breast Feeding, Family medicine, Medicine, Humans, Pharmacology (medical), Female, business
Published
2023

2. Gestational diabetes in women living with HIV in Botswana: lower rates with dolutegravir- than with efavirenz-based antiretroviral therapy

Author

Gosego Masasa, Shan Sun, Terrence Mohammed, Mompati Mmalane, Irwin J. Kurland, Kathleen M. Powis, K. N. Mmasa, Sikhulile Moyo, J. Legbedze, Samuel Kgole, Mariana Gerschenson, Elaine J. Abrams, Mitchell E. Geffner, Jennifer Jao, and Joseph Makhema

Subjects
0301 basic medicine, Adult, Cyclopropanes, medicine.medical_specialty, Efavirenz, Adolescent, Pyridones, HIV Infections, Emtricitabine, Lower risk, Piperazines, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, Diabetes mellitus, Oxazines, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Botswana, Obstetrics, business.industry, Health Policy, virus diseases, medicine.disease, 030112 virology, Benzoxazines, Gestational diabetes, Diabetes, Gestational, Infectious Diseases, chemistry, Alkynes, Dolutegravir, Gestation, Female, business, Heterocyclic Compounds, 3-Ring, medicine.drug
Abstract

BACKGROUND There are few data on the prevalence of gestational diabetes (GDM) in pregnant women living with HIV (WLHIV) in sub-Saharan Africa, particularly those using integrase strand transfer inhibitors such as dolutegravir (DTG). METHODS We prospectively enrolled pregnant WLHIV and pregnant women without HIV ≥18 years old in Gaborone, Botswana, excluding those with pre-existing diabetes. We screened for GDM using a 75 g oral glucose tolerance test (OGTT) performed at 24-28 weeks' gestation or at the earliest prenatal visit for those presenting after 28 weeks. Logistic regression models were fitted to assess the association between maternal HIV infection and GDM. Subgroup analyses were performed among WLHIV to assess the association between maternal antiretroviral therapy (ART) in pregnancy [DTG vs. efavirenz (EFV) with tenofovir/emtricitabine] and GDM. RESULTS Of 486 pregnant women, 66.5% were WLHIV, and they were older than women without HIV (median age 30 vs. 25 years, P

Published
2021

3. Fetal biometry following in-utero exposure to dolutegravir-based or efavirenz-based antiretroviral therapy

Author

Lynn M. Yee, Gosego Masasa, Joseph Makhema, Shan Sun, Francis Msume Banda, Jennifer Jao, and Kathleen M. Powis

Subjects
Cyclopropanes, Pediatrics, medicine.medical_specialty, Biometry, Efavirenz, Pyridones, Immunology, HIV Infections, Article, Piperazines, Ultrasonography, Prenatal, chemistry.chemical_compound, Fetus, Pregnancy, Oxazines, medicine, Humans, Immunology and Allergy, HIV Integrase Inhibitors, Pregnancy Complications, Infectious, business.industry, Antiretroviral therapy, Benzoxazines, Infectious Diseases, chemistry, Fetal biometry, In utero, Alkynes, Dolutegravir, Reverse Transcriptase Inhibitors, Female, business, Heterocyclic Compounds, 3-Ring
Published
2020
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