1. Poster Abstracts
- Author
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Antonio Carrillo, J. M. Campistol, P. Ventura, J. V. Torregrosa, Frederic Cofan, Fritz Diekmann, Nuria Esforzado, I. Revuelta, Gastón J Piñeiro, Beatriu Bayés, Marc Xipell, Jessica Ugalde-Altamirano, David Cucchiari, Frederic Oppenheimer, E. Montagud, and A. Molina
- Subjects
Transplantation ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,medicine.disease ,Gastroenterology ,vitamin D deficiency ,Bolus (medicine) ,medicine.anatomical_structure ,Methylprednisolone ,Apoptosis ,Internal medicine ,Vitamin D and neurology ,Immunology and Allergy ,Medicine ,Pharmacology (medical) ,In patient ,business ,Pancreas ,medicine.drug - Abstract
Purpose: The protective role of Vitamin D as an immunomodulator has been demonstrated in different pathologies included the viral etiology. This effect has been described by different mechanisms among these acting as an immunoprotein inducer, participates in growth and cell differentiation and acts as a mediator of apoptosis. Some evidence suggests that it could influence the SARS-COV 2 infection and its prognosis. Kidney transplant (KT) patients are more susceptible to 25 (OH) VitD (Calcidiol) deficiencies. The purpose of this study is to evaluate the Vitamin D status in transplant patients who have been diagnosed with COVID-19 and its possible correlation with prognosis. Methods: It is an observational, retrospective, cross-sectional and descriptive study that includes kidney transplant patients diagnosed with COVID-19 and with serum 25 (OH) Vit D Results: 79 patients were evaluated. The mean age was 58 years, 60.8% were men. 86% were KT, 11% were simultaneous pancreas and kidney transplant (SPK). 39 (48%) presented neumonia, 22 (28%)flu-like syndrom. 14 (17%) asyntomatic and 2(2,5%) fever. From this patients 39,2% had not changes in the antiinflamatorie therapy, 20.3%, required increased dose of corticosteroids, and 30.4% required methylprednisolone bolus or initiation of anti-interleukin therapy. The mean of Vit D was 21.41+/- 11% we found that 52% has Vit D 30 ng / dl In 32 patientes who required intensification of treatment we found that 73% had Vit D levels
- Published
- 2021