1. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for the diagnosis and prognosis in patients with restenosis following CAS
- Author
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Fengfeng Jiang, Zhou Gezhi, Bao Xiang, Wei Xu, Liu Xiaobo, and Ye Zhijun
- Subjects
Male ,medicine.medical_specialty ,Neutrophils ,Lymphocyte ,Clinical Biochemistry ,030204 cardiovascular system & hematology ,Coronary Restenosis ,03 medical and health sciences ,0302 clinical medicine ,Restenosis ,Internal medicine ,Drug Discovery ,Medicine ,Humans ,In patient ,Platelet ,Lymphocyte Count ,Lymphocytes ,Neutrophil to lymphocyte ratio ,Aged ,Retrospective Studies ,Receiver operating characteristic analysis ,business.industry ,Incidence (epidemiology) ,fungi ,Biochemistry (medical) ,Angioplasty ,Area under the curve ,Middle Aged ,medicine.disease ,Prognosis ,humanities ,eye diseases ,medicine.anatomical_structure ,Carotid Arteries ,embryonic structures ,Cardiology ,Female ,Stents ,business ,human activities ,030217 neurology & neurosurgery - Abstract
Aim: In this study, we investigated the effect of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio on restenosis status in patients undergoing carotid angioplasty stenting (CAS). Methodology & results: Clinical imageology and receiver operating characteristic analysis were utilized to study the prognostic significance of NLRs/platelet-to-lymphocyte ratios and their correlation with survival. NLR of restenosis (+) patients was evidently increased after the CAS procedures, while the NLR of restenosis (-) patients before the CAS procedures being the lowest. Area under the curve of pre-CAS NLR or/and post-CAS NLR were all evidently higher than 50%. Also, restenosis incidence was the highest in patients with both high pre-CAS and high post-CAS values. Conclusion: Therefore, NLR can be utilized as an independent prognostic indicator to predict the incidence of restenosis after CAS procedures.
- Published
- 2020