1. Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets
- Author
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Haihua Wang, Xin Wu, Chunyan Xie, Kai-Min Niu, Xiaoxiao Liang, Junwei Shan, and Yumei Zhang
- Subjects
Litter (animal) ,chemistry.chemical_classification ,business.industry ,medicine.drug_class ,Evaluation data ,Antibiotics ,chemistry.chemical_element ,Zinc ,Enteromorpha polysaccharide-zinc chelate ,Body weight ,Polysaccharide ,SF1-1100 ,Animal culture ,Weaned piglet ,Intestinal development ,Basal (phylogenetics) ,Animal science ,Food Animals ,chemistry ,Weaned piglets ,Medicine ,Animal Science and Zoology ,Original Research Article ,business ,Prophylactic antibiotic - Abstract
This research aimed to study whether Enteromorpha polysaccharide-zinc (EP-Zn) can act as an alternative to antibiotics in weaned piglet feeds. Two hundred and twenty-four weaned piglets from 14 pens were randomly assigned into 1 of 2 groups according to their body weight and litter size (7 pens/group). The piglets in the antibiotics group were fed with olaquindox at 400 mg/kg and enduracidin at 800 mg/kg basal diet, and piglets in the EP-Zn group were fed with EP-Zn at 800 mg/kg basal diet. One piglet per pen was selected to collect samples after 14 d of feeding. Results showed that EP-Zn supplementation significantly increased the plasma anti-oxidants level compared with the antibiotics group. However, a nonsignificant difference was observed in growth performance between treatment groups. Additionally, the intestinal tight junction (TJ) protein expression and the histopathologic evaluation data showed that EP-Zn contributed to improving intestinal development. Further, piglets in the EP-Zn group had a lower level of intestinal inflammation-related cytokines including IL-6 (P
- Published
- 2021
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