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In the context of the current widespread large classes teaching in universities of China, an in-depth analysis was carried out from the perspective of knowledge dissemination within internal organization and Collaborative Knowledge Building, the existing teaching pattern was generalized as a pyramid-shaped model, which is not conducive to the spread of knowledge in large classes. In order to achieve good teaching effects, the traditional communication way should be changed. An open communication network platform should be employed to promote knowledge dissemination within large classes. Easyclass was used to facilitate teaching for a large class over 150 registered students in Database Application. An outline of the teaching mode was given thoroughly in this paper.