1. Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation:an analysis from the ESC-EHRA EORP Atrial Fibrillation General Long-Term (AFGen LT) Registry
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Cuisset, Thomas, Fauchier, Laurent, Deharo, Pierre, Cohen, Ariel, Waldmann, Victor, Bouzeman, Abdeslam, Duthoit, Guillaume, Koutbi, Linda, Bessiere, Francis, Labombarda, Fabien, Marquié, Christelle, Gourraud, Jean Baptiste, Mondoly, Pierre, Sellal, Jean Marc, Bordachar, Pierre, Hermida, Alexis, Anselme, Frédéric, Asselin, Anouk, Audinet, Caroline, Bernard, Yvette, Boveda, Serge, Bru, Paul, Bun, Sok Sithikun, Clerici, Gael, da Costa, Antoine, de Guillebon, Maxime, Defaye, Pascal, Elbaz, Nathalie, Eschalier, Romain, Garcia, Rodrigue, Guenancia, Charles, Guy-Moyat, Benoit, Halimi, Franck, Irles, Didier, Iserin, Laurence, Jourda, François, Ladouceur, Magalie, Lagrange, Philippe, Laredo, Mikael, Mansourati, Jacques, Massoulié, Grégoire, Mathiron, Amel, Maury, Philippe, Messali, Anne, Narayanan, Kumar, Nguyen, Cédric, Ninni, Sandro, Perier, Marie-Cécile, Pierre, Bertrand, Pujadas, Penelope, Sacher, Frédéric, Sagnol, Pascal, Sharifzadehgan, Ardalan, Walton, Camille, Winum, Pierre, Zakine, Cyril, Martins, Raphael, Pasquié, Jean Luc, Thambo, Jean Benoit, Jouven, Xavier, Combes, Nicolas, Marijon, Eloi, Squara, Fabien, Theodore, Guillaume, Scarlatti, Didier, Hourdain, Jérome, Deharo, Jean-Claude, Ollitrault, Pierre, Milliez, Paul, Champ-Rigot, Laure, Bader, Hugues, Duplantier, Cécile, Milhem, Antoine, Sagnard, Audrey, Bertaux, Géraldine, Laurent, Gabriel, Badoz, Marc, Bortone, Agustin, Laborie, Guillaume, Rollin, Anne, Stephanopoli, Quentin Voglimacci, Mandel, Franck, Duparc, Alexandre, Domain, Guillaume, Albenque, Jean-Paul, Cardin, Christèle, Combes, Stéphane, Tanese, Nikita, Hasni, Karim, Leclercq, Christophe, Galand, Vincent, Pavin, Dominique, Mabo, Philippe, Behar, Nathalie, Clementy, Nicolas, Loose, Christophe, Otmani, Akli, Venier, Sandrine, Carabelli, Adrien, Jacon, Peggy, Kilani, Mouna Ben, Guichard, Jean Bapstist, Romeyer-Bouchard, Cécile, Le Gloan, Laurianne, Probst, Vincent, Freysz, Luc, Blangy, Hugues, Chillou, Christian De, Sadoul, Nicolas, Khattar, Pierre, Potelle, Charlotte, Jean, Frederic, Puie, Paul, Khoueiry, Ziad, Chevallier, Philippe, Dulac, Arnaud, Filippo, Sylvie Di, Gardey, Kevin, Frey, Pierre, Akret, Chrystelle, Dompnier, Antoine, Maupain, Carole, Waintraub, Xavier, Hidden-Lucet, Françoise, Chastre, Thomas, Gandjbakhch, Estelle, Badenco, Nicolas, Extramiana, Fabrice, Leenhardt, Antoine, Zouaghi, Amir, Algalarrondo, Vincent, Amet, Denis, Varlet, Emilie, Chalbia, Tej, Philibert, Séverine, Ollitrault, Jacky, Lavergne, Thomas, Baudinaud, Pierre, Mirolo, Adrian, Savouré, Arnaud, Godin, Bénédicte, Bertrand, Cathy, Fiorello, Pierre, Johnson, Nicolas, Lallemand, Pierre-Marc, Herminda, Alexis, Hermida, Jean-Sylvain, Degand, Bruno, Bouazzaou, Rim El, Mourot, Stéphane, Goussot, Samuel, Jauvert, Gaël, Lazarus, Arnaud, Grimard, Caroline, Alonso, Christine, Zhao, Alexandre, Thomas, Olivier, Cauchemez, Bruno, Moubarak, Ghassan, Lellouche, Nicolas, Hamon, David, Enache, Bogdan, Lactu, Gabriel, Wiart, Françoise, Geoffroy, Olivier, Poindron, Damien, Maltret, Alice, Raimondo, Cristine, Bonnet, Damien, Hascoët, Sébastien, Derval, Nicolas, Haïssaguerre, Michel, Hocini, Mélèze, Proietti, Marco, Lip, Gregory, Laroche, Cécile, Marin, Francisco, Nabauer, Michael, Potpara, Tatjana, Dan, Gheorghe-Andrei, Kalarus, Zbigniew, Tavazzi, Luigi, Maggioni, Aldo Pietro, Boriani, Giuseppe, Hôpital de la Timone [CHU - APHM] (TIMONE), Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Paris Cité (UPCité), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Hospitalier de Versailles André Mignot (CHV), CHU Pitié-Salpêtrière [AP-HP], Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Hôpital Louis Pradel [CHU - HCL], Hospices Civils de Lyon (HCL), Signalisation, électrophysiologie et imagerie des lésions d’ischémie-reperfusion myocardique (SEILIRM), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre hospitalier universitaire de Nantes (CHU Nantes), Service Cardiologie [CHU Toulouse], Pôle Cardiovasculaire et Métabolique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] (CRCTB), Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Amiens-Picardie, Service de cardiologie [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Groupe Hospitalier Bretagne Sud (GHBS), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Clinique Pasteur, Clinique Pasteur [Toulouse], Service de cardiologie, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Hôpital Pasteur [Nice] (CHU), CHU Saint-Pierre, Università degli Studi di Milano = University of Milan (UNIMI), Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, University of Liverpool, Aalborg University [Denmark] (AAU), EURObservational Research Programme, European Society of Cardiology, Universidad de Murcia, University of Belgrade [Belgrade], Colentina University Hospital, University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), Silesian Medical University, Katowice, Poland, University Hospital of Ferrara and Maria Cecilia Hospital, Associazione Nazionale Medici Cardiologi Ospedalieri [Firenze] (ANMCO), Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de cardiologie
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medicine.medical_specialty ,Acute coronary syndrome ,030204 cardiovascular system & hematology ,Lower risk ,[SHS]Humanities and Social Sciences ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Physiology (medical) ,Internal medicine ,Thromboembolism ,Atrial Fibrillation ,Care pathway ,Medicine ,Humans ,030212 general & internal medicine ,Registries ,Outcomes • Registry ,business.industry ,Hazard ratio ,Anticoagulants ,Integrated care ,Atrial fibrillation ,medicine.disease ,Confidence interval ,3. Good health ,Stroke ,Cohort ,Cardiology and Cardiovascular Medicine ,business - Abstract
Aims There has been an increasing focus on integrated, multidisciplinary, and holistic care in the treatment of atrial fibrillation (AF). The ‘Atrial Fibrillation Better Care’ (ABC) pathway has been proposed to streamline integrated care in AF. We evaluated the impact on outcomes of an ABC adherent management in a contemporary real-life European-wide AF cohort. Methods and results Patients enrolled in the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry with baseline data to evaluate ABC criteria and available follow-up data were considered for this analysis. Among the original 11 096 AF patients enrolled, 6646 (59.9%) were included in this analysis, of which 1996 (30.0%) managed as ABC adherent. Patients adherent to ABC care had lower CHA2DS2-VASc and HAS-BLED scores (mean ± SD, 2.68 ± 1.57 vs. 3.07 ± 1.90 and 1.26 ± 0.93 vs. 1.58 ± 1.12, respectively; P Conclusion In a large contemporary cohort of European AF patients, a clinical management adherent to ABC pathway for integrated care is associated with a significant lower risk for cardiovascular events, CV death, and all-cause death.
- Published
- 2021