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Objectives This study sought to establish a mapping and ablation strategy to target intramural ventricular arrhythmias (VAs) by identifying the precise arrhythmia site of origin (SOO). Background Radiofrequency ablation of intramural VAs is challenging because the arrhythmia origin is difficult to localize. Methods In 83 consecutive patients with intramural VAs, a stepwise mapping approach was performed: ablation targeted directly the SOO when possible followed by the closest adjacent anatomical structure when necessary. If the SOO could not be identified, the earliest endocardial breakout sites were ablated. Safety and procedural outcomes between patients in whom the SOO could and could not be identified were compared. Results The SOO was identified in 19 of 83 (23%) patients, and radiofrequency ablation was effective in eliminating VAs in all 19 (100%) patients by ablation at the SOO alone (n = 3), at the SOO and an anatomically adjacent area (n = 7), or at an anatomically adjacent area alone (n = 9). Breakout site mapping and ablation in the remaining 64 patients in whom the SOO was not identified was effective in 43 of 64 patients, which was significantly less than in patients in whom the SOO was identified (67% vs. 100%; p Conclusions Identification of the SOO was associated with a successful ablation procedure by either targeting the SOO directly or targeting an adjacent anatomical structure. Ablation at the breakout sites of intramural VAs has a lower efficacy than when the SOO can be directly targeted.

Agri-environment schemes (AES) favouring the maintenance of hedges were implemented in the Camargue (southern France) as it has previously been proven to reduce the risk of damage caused by Greater Flamingo incursions into rice fields. Given the persistent incursions, we estimated the economic cost of damage from 2007 to 2009, the uptake rate of hedge-related AES and explored the limits of these schemes as a mitigation effort. Semi-structured and key informant interviews, site mapping and field visits were made to verify claims and estimate damage. Number of plants/m2 and fertile stems/plant were estimated on 1,498 and 312 grids, respectively, spread over 26 rice fields. Damaged areas of rice fields forayed by flamingos presented from 1.35 to 3.06 t/ha lower yield than undamaged areas. We estimated 228€/ha average loss in forayed fields for a total of 400,000€ in yield loss in 2008. Administrative constraints limited AES and free seedlings distribution, preventing the problem from being addressed at an ap...

Plastic covering is a common practice in agricultural fields. From an agronomic point of view, plastic coverings offer many advantages against unfavourable growing conditions. This explains their widespread utilization with consequent positive impact on local economy. On the other hand, plasticulture raises both environmental and landscape issues. In the Apulia Region (Italy) the wide implementation of such practice generally relates to vineyard cultivation. Continuous vineyard protection has resulted in negative effects on the hydrogeological balance of soils, causing a deep modification of the traditional rural landscape and therefore affecting its quality. To guarantee both the protection of local economy as well as the preservation of local environment and landscape features, a detailed site mapping of the areas involved is necessary. Indeed, the quantification of this phenomenon is essential in the periodic updating of the existing land use database and in the development of local policies. In this study we evaluate the potential of the novel Thermal Infrared Sensor bands (TIRS) provided by the LANDSAT 8 mission in plasticulture discrimination. Using the evident anomaly retrieved in the study area on the Quality Assessment (QA) band, a fast procedure involving TIRS data was developed, proposing a new index (Plastic Surface Index- PSI) able to emphasize plasticulture. For the aim of this study, two different acquisition dates on a test area in the Apulia region (Italy) were analyzed, one in the growing season with high plastic covering density and one in the post-harvest period with low plastic cover density.

SummaryBackground While sunlight is important in the aetiology of cutaneous malignant melanoma (CMM), the relationship between skin areas receiving intermittent or chronic sun exposure and the development of CMM has not been fully explored. There is a requirement for an improved method for more detailed site mapping and for analysis of tumour density in different areas of the skin in relation to the type of sun exposure, phenotypic traits and prognosis of patients with CMM. Objectives To describe and demonstrate the use of EssDoll©, a new computerized method to map and analyse tumour sites. Methods We have used the new software to analyse data on 2517 patients with 2608 primary CMMs. Results The results obtained were consistent with previous data on the distribution of CMM in men and women. The distribution of CMM on the back was uneven, with the density on the upper back being twice that on the lower back. Conclusions The new methodology allows a more accurate mapping and analysis of skin tumour site, including determination of tumour density. This improves the possibility of analysing tumour site in relation to aetiological, phenotypic and prognostic parameters.

Plastic covering is used worldwide to protect crops against damaging growing conditions. This agricultural practice raises some controversial issues. While it significantly impacts on local economic vitality, plasticulture also shows several environmental affects. In the Apulia Region (Italy) the wide-spreading of artificial plastic coverings for vineyard protection has showed negative consequences on the hydrogeological balance of soils as well as on the visual quality of rural landscape. In order to monitor and manage this phenomenon, a detailed site mapping has become essential. In this study an efficient object-based classification procedure from Very High Spatial Resolution (VHSR) true color aerial data was developed on eight test areas located in the Ionian area of the Apulia Region in order to support the updating of the existing land use database aimed at plastic covered vineyard monitoring.

This report documents data collection, results, and interpretation of the expedited site characterization (ESC) pilot project conducted from September 1996 to June 1997 at the Central Nevada Test Area (CNTA), Nye County, Nevada. Characterization activities were limited to surface sites associated with deep well drilling and ancillary operations at or near three emplacement well areas. Environmental issues related to the underground nuclear detonation (Project Faultless) and hydrologic monitoring wells were not addressed as a part of this project. The CNTA was divided into four functional areas for the purpose of this investigation and report. These areas include the vicinity of three emplacement wells (UC-1, UC-3, and UC-4) and one mud waste drilling mud collection location (Central Mud Pit; CMP). Each of these areas contain multiple, potentially contaminated features, identified either from historic information, on-site inspections, or existing data. These individual features are referred to hereafter as ``sites.`` The project scope of work involved site reconnaissance, establishment of local grid systems, site mapping and surveying, geophysical measurements, and collection and chemical analysis of soil and drilling mud samples. Section 2.0 through Section 4.0 of this report provide essential background information about the site, project, and details of how the ESC method was applied at CNTA. Detailed discussion of the scope of work is provided in Section 5.0, including procedures used and locations and quantities of measurements obtained. Results and interpretations for each of the four functional areas are discussed separately in Sections 6.0, 7.0, 8.0, and 9.0. These sections provide a chronological presentation of data collected and results obtained, followed by interpretation on a site-by-site basis. Key data is presented in the individual sections. The comprehensive set of data is contained in appendices.

Complex Fractionated Atrial Electrogram (CFAE) is associated with atrial fibrillation (AF) substrate. Culprit CFAE site might be pivot point of rotor wave. However, several sites with CFAE might behave just as bystander sites showing passive fibrillatory conduction. If AF termination is not obtained, is it no use ablating CFAE sites?CFAE ablation would eliminate fibrillatory conduction and help organizing AF, changing AF to atrial tachycardia (AT). CFAE might be related to the focus of driver (AT focus) or the site with activation gradient showing local reentry in small area. Therefore CFAE ablation would restore sinus rhythm in multi factorial ways. Recently important electrophysiological roles of ganglionated plexi (GP) have been emphasized. GP site is defined as showing parasympathetic response to high frequency stimulation. The sites of GP and CFAE are reported to overlap, however, details are unknown. We performed CFAE mapping by measuring fibrillation cycle length and displayed the sites of GP on that map. The result showed wide variety of fibrillation cycle length (30–176 ms) at the GP site. Although GP site may not demonstrate shortest fibrillation cycle length, GP site ablation eliminated AF inducibility in several cases, demonstrating GP is another important marker of AF substrate ablation, apart from CFAE ablation strategy.

The ability to accurately determine the number of syringe needle penetration holes through the rubber stoppers in pharmaceutical vials and rubber septa in intravenous (i.v.) line and bag ports has been a critical factor in a number of forensic cases involving the thefts of controlled substances or suspected homicide by lethal injection. In the early 1990s, the microscopy and microanalysis group of the U.S. Food and Drug Administration's Forensic Chemistry Center (FCC) developed and implemented a method (unpublished) to locate needle punctures in rubber pharmaceutical vial stoppers. In 1996, as part of a multiple homicide investigation, the Indiana State Police Laboratory (ISPL) contacted the FCC for information on a method to identify and count syringe needle punctures through rubber stoppers in pharmaceutical vials. In a joint project and investigation using the FCC's needle hole location method and applying a method of puncture site mapping developed by the ISPL, a systematic method was developed to locate, identify, count, and map syringe punctures in rubber bottle stoppers or i.v. bag ports using microscopic analysis. The method requires documentation of punctures on both sides of the rubber stoppers and microscopic analysis of each suspect puncture site. The final result of an analysis using the method is a detailed diagram of puncture holes on both sides of a questioned stopper and a record of the minimum number of puncture holes through a stopper.

The subdivision of land for residential purposes requires the prior identification of hazards to development, and engineering geological assessment techniques form an integral part of sound urban planning practices. Selected examples from South Island localities illustrate our engineering geological approach to subdivision planning, which involves site mapping, test-pit logging and limited geotechnical testing, and we outline recommended practices for the preparation of scheme and concept plans. Proposed residential subdivision sites are assessed in terms of those active (geomorphic) processes that led to their development, and the future occurrence of damaging events is quantified in terms of the available historic and/or geologic record. A site model is also developed to integrate surface and subsurface geology with available geotechnical data, thereby identifying those parts of the subdivision that require additional investigation at the detailed design or construction stages, and likewise delineating those areas that are unsuitable for residential development because of geologic or topographic constraints.