1. Effects of lower limb segmental muscle vibration on primary motor cortex short-latency intracortical inhibition and spinal excitability in healthy humans
- Author
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Akihiko Ohwatashi, Atsuo Maruyama, Takehiro Kuronita, Seiji Etoh, Kodai Miyara, Kentaro Kawamura, and Megumi Shimodozono
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medicine.medical_specialty ,Neurology ,business.industry ,General Neuroscience ,medicine.medical_treatment ,Long-term potentiation ,medicine.disease ,Transcranial magnetic stimulation ,Internal medicine ,medicine ,Cardiology ,Intracortical inhibition ,Abductor hallucis muscle ,Spasticity ,medicine.symptom ,Primary motor cortex ,business ,Stroke - Abstract
We examined the effects of lower limb segmental muscle vibration (SMV) on intracortical and spinal excitability in 13 healthy participants (mean age: 34.9 ± 7.8 years, 12 males, 1 female). SMV at 30 Hz was applied to the hamstrings, gastrocnemius, and soleus muscles for 5 min. Paired-pulse transcranial magnetic stimulation protocols were used to investigate motor-evoked potential (MEP) amplitude, short-interval intracortical inhibition (SICI) and short-interval intracortical facilitation (SICF) from the abductor hallucis muscle (AbdH). These assessments were compared to the results of a control experiment (i.e., non-vibration) in the same participants. F-waves were evaluated from the AbdH on the right (vibration side) and left (non-vibration side) sides, and we calculated the ratio of the F-wave amplitude to the M-response amplitude (F/M ratio). These assessments were obtained before, immediately after, and 10, 20, and 30 min after SMV. For SICI, there was no change immediately after SMV, but there was a decrease over time (before vs. 30 min after, p = 0.021; immediately after vs. 30 min after, p = 0.015). There were no changes in test MEP amplitude, SICF, or the F/M ratio. SMV causes a gradual decrease in SICI over time perhaps owing to long-term potentiation. The present results may have implications for the treatment of spasticity.
- Published
- 2021
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