1. Calciphylaxis After Aortic Valve Replacement in a Patient with End-Stage Renal Disease
- Author
-
Ryoji Kinoshita, Ekapot Bhunchet, Yuichi Araki, Yohei Yamamoto, Hidetoshi Uchiyama, Masahiro Oonuki, Hiroyuki Tanaka, Yoshihiro Moriyama, Kazunobu Hirooka, and Keisuke Anju
- Subjects
medicine.medical_specialty ,Calciphylaxis ,end-stage renal disease ,calciphylaxis ,business.industry ,Case Report ,General Medicine ,medicine.disease ,Surgery ,End stage renal disease ,Aortic valve replacement ,medicine ,aortic valve replacement ,business - Abstract
In this study, we report a case of a patient on dialysis who presented necrotic lesions on the legs and penile ulceration 7 years after a mechanical aortic valve replacement. The diagnosis of calciphylaxis was not confirmed even after skin biopsy, and multidisciplinary management was not initiated until the patient was admitted with septic shock. Cardiovascular surgeons should be aware of warfarin-induced calciphylaxis, whose pathophysiology differs from that of atherosclerosis. Considering poor long-term survival of dialysis patients, mechanical valves should be reserved only for those patients whose estimated survival is longer than the time taken for a biological valve to deteriorate. more...
- Published
- 2021
- Full Text
- View/download PDF