16 results on '"Ying-Liang Wu"'
Search Results
2. Effects of acute and chronic administration of MK-801 on c-Fos protein expression in mice brain regions implicated in schizophrenia with or without clozapine
- Author
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Haifeng Wang, Dai-Ying Zuo, Yue Cao, Ying-Liang Wu, and Lan Zhang
- Subjects
Male ,medicine.medical_specialty ,Psychosis ,Gene Expression ,Mice ,Internal medicine ,Cortex (anatomy) ,medicine ,Animals ,Prefrontal cortex ,Clozapine ,Biological Psychiatry ,Brain Chemistry ,Pharmacology ,business.industry ,Glutamate receptor ,Genes, fos ,medicine.disease ,Immunohistochemistry ,Dizocilpine ,Endocrinology ,medicine.anatomical_structure ,Posterior cingulate ,Schizophrenia ,NMDA receptor ,Dizocilpine Maleate ,business ,Excitatory Amino Acid Antagonists ,Proto-Oncogene Proteins c-fos ,Antipsychotic Agents ,medicine.drug - Abstract
This study investigated the effects of acute and chronic administration of the non-competitive NMDA receptor antagonists MK-801 on c-Fos protein expression in different brain regions of mice with or without clozapine. MK-801 (0.6 mg/kg) acute administration produced a significant increase in the expression of c-Fos protein in the layers III-IV of posterior cingulate and retrosplenial (PC/RS) cortex, which was consistent with the previous reports. Moreover, we presented a new finding that MK-801 (0.6 mg/kg) chronic administration for 8 days produced a significant increase of c-Fos protein expression in the PC/RS cortex, prefrontal cortex (PFC) and hypothalamus of mice. Among that, c-Fos protein expression in the PC/RS cortex of mice was most significant. Compared to acute administration, we found that MK-801 chronic administration significantly increased the expression of c-Fos protein in the PC/RS cortex, PFC and hypothalamus. Furthermore, pretreatment of mice with clozapine significantly decreased the expression of c-Fos protein induced by MK-801 acute and chronic administration. These results suggest that c-Fos protein, the marker of neuronal activation, might play an important role in the chronic pathophysiological process of schizophrenic model induced by NMDA receptor antagonist.
- Published
- 2009
3. TOPSIS-based synthetic evaluation method for customer satisfaction
- Author
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Xing-Yan Zhu and Ying-Liang Wu
- Subjects
Service quality ,Voice of the customer ,Knowledge management ,Process management ,Standardization ,business.industry ,Computer science ,Information system ,Entropy (information theory) ,Service level objective ,Customer satisfaction ,TOPSIS ,business - Abstract
Quantitative evaluation of service quality is very important in modern service industry, so there has important theoretical and practical significance of studying comprehensive evaluation method of customer satisfaction. This paper discusses customer satisfaction concept and constructs evaluation index system for customer satisfaction oriented information service, then describes the theories and procedures of TOPSIS evaluation method and entropy weighted method. Finally, this paper takes university library-a typical kind of information service industry for example, using TOPSIS method to evaluate the library's reader satisfaction, discusses the evaluation results and gives suggestions for improving its information service quality and level based on the results.
- Published
- 2011
4. Research on the E-Commerce-oriented solution of reengineering and operating of business model of specialized market in China: With the case of SJQ.cn
- Author
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Ying-Liang Wu and Yuqiong Yang
- Subjects
Structure (mathematical logic) ,Distributed database ,business.industry ,Computer science ,media_common.quotation_subject ,E-commerce ,Business process reengineering ,Modular design ,Business model ,Manufacturing engineering ,The Internet ,Marketing ,business ,Function (engineering) ,media_common - Abstract
This paper systematically analyzed specialized market's demands and business models of E-Commerce, made a research on the construction of E-Commerce platform for specialized market, and presented the general system structure. On this basis, a modular and integrate function structure was proposed by structural system design. Finally we used a specific case to provide a feasible solution for the development of E-Commerce platform for specialized market.
- Published
- 2011
5. Research on the Wiki & HIS-Based Application Mode of Hospital Knowledge Management
- Author
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Ying-liang Wu and Chuan-yang Wang
- Subjects
Hospital information system ,Information management ,InformationSystems_GENERAL ,Knowledge management ,Mode (computer interface) ,business.industry ,Computer science ,Data management ,Information system ,Informatization ,Construct (philosophy) ,business ,Requirements analysis - Abstract
Through the requirement analysis of hospital management, the paper elaborates the necessity and feasibility of hospital informatization from the traditional information management to knowledge management based on the hospital information system (HIS hereafter). With the discussion of knowledge management mechanisms and characteristics of Wiki, a Wiki & HIS-based application mode of hospital knowledge management is put forward with a case of the clinician combined with his practical application. This solution can organically match the e-commerce service mode and the techniques of Web2.0 to the requirement of hospital knowledge management, and is helpful to construct the new dynamic, open, distributed and service-oriented hospital information system.
- Published
- 2010
6. The Industry Information Oriented Construction and Operating of E-Exchange
- Author
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Ying-liang Wu, Chen Han, and Cheng-zhou Wu
- Subjects
Industry classification ,Commerce ,Electronic business ,business.industry ,Software construction ,Information system ,Information revolution ,Business ,E-commerce ,Business model ,Industrial organization ,Plastics industry - Abstract
The main role of E-Business in the information revolution concentrates on reconstructing and optimizing the traditional business model and the mechanism of value-creating. With the development of the industry information, many types of e-markets have been emerging, and E-exchange is just one of them. On the background of Guangdong Plastics Exchange’s practical program construction, the article summarizes and analyses the concept and characters of E-exchange on the basic of the construction of the plastics exchange e-market, and describes all its functions, as well as opens out the business model and operation mechanism. Finally, it points out that developing and constructing staple commodity exchange e-markets that orient to different industries, would be an important prospect of the industry information in future in China.
- Published
- 2010
7. Research on the Knowledge Management Solution for Learning Organizations
- Author
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Yu-qiong Yang and Ying-liang Wu
- Subjects
Software ,Knowledge management ,business.industry ,Computer science ,Data management ,Organizational learning ,Knowledge engineering ,Personal knowledge management ,Knowledge value chain ,Domain knowledge ,Learning organization ,business - Abstract
This paper carried on an analysis to the knowledge management requirements of learning organizations. Based on the requirements and the knowledge management methods, a new knowledge management solution on the learning organizations has been proposed, and the functions of the new solution have been pointed out concretely.
- Published
- 2010
8. Research on the Evaluation Method for Enterprise Knowledge Management Performance Based on Triangular Fuzzy Number
- Author
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Ying-liang Wu and Xing-Yan Zhu
- Subjects
Index (economics) ,Empirical research ,Knowledge management ,Order (exchange) ,Computer science ,business.industry ,Capital (economics) ,Fuzzy set ,Fuzzy number ,business ,Fuzzy logic ,Intellectual capital - Abstract
To evaluate exactly the performance of knowledge management (KM) is an important part of the construction of enterprise knowledge management systems. Based on enterprise capital, a performance evaluation index system has designed by using intellectual capital, organization capital and market capital as subjects in this paper. In order to realize quantitative calculation for qualitative index, a fuzzy calculation method, that is triangular fuzzy number (TFN) evaluation method is proposed. Then the method’s theory and steps are discussed. Finally, the empirical study has been done on three IT enterprises, use TFN method to evaluate their KM performance, and some improvement suggestions are given based on evaluation results.
- Published
- 2010
9. A Knowledge Management Solution Based on Enterprise Information Portal
- Author
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Xue Wang and Ying-Liang Wu
- Subjects
Knowledge management ,Process management ,Enterprise architecture management ,business.industry ,Computer science ,Enterprise integration ,Enterprise architecture ,Integrated enterprise modeling ,Enterprise application integration ,Enterprise information system ,business ,Enterprise planning system ,Enterprise software - Abstract
Knowledge management (KM) is a new problem for e- commerce and enterprise application integration (EAI) , and it has become one of the research front and hotspots in management science and engineering. In this paper, the requirements and key problems of e-commerce application oriented enterprise KM are discussed, a enterprise information portal(EIP) based KM solution is presented, the key techniques for implementation are pointed. At last, a case of Midea is studied, in addition, the developing trends and foreground of KM are discussed also.
- Published
- 2009
10. Research on the Performance Measurement of Knowledge Management Based on Principal Component Analysis
- Author
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Ying-Liang Wu, Hao-Su Wu, and Xue Wang
- Subjects
Information management ,Knowledge management ,Index system ,business.industry ,Computer science ,Organizational learning ,Principal component analysis ,Performance measurement ,Learning organization ,business ,Maturity (finance) ,Case analysis - Abstract
As an important part of knowledge management (KM), the KM performance evaluation tries to find out the key factors restraining the enhancement of the enterprises' performance. In this paper, some primary factors of the performance of enterprises KM are analyzed and an index system of KM performance is established by considering some aspects, such as marketing capability, information management, maturity degree of the learning organizations, and knowledge stocks. A principal component analysis and the arithmetic steps for principal component analysis are presented to evaluate the KM performance. The case analysis shows that the principal component analysis method is efficient and practical for the KM performance evaluation.
- Published
- 2009
11. Research on the Overall Framework of Knowledge Management
- Author
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Jing-Jing Pang and Ying-Liang Wu
- Subjects
Information management ,Process management ,Knowledge management ,business.industry ,Computer science ,Program management ,Data management ,Knowledge engineering ,Knowledge value chain ,Mathematical knowledge management ,computer.software_genre ,Technology management ,Systems management ,Organizational learning ,Personal knowledge management ,Enterprise relationship management ,Domain knowledge ,business ,Digital firm ,Management process ,computer - Abstract
Dispute about conception and research area of knowledge management exists always. In order to distinguish and evaluate about the influence factor of the success or failure of knowledge management project, it is necessary to understand it in the point of system thought and to design an integrated entirely knowledge management framework model that is accepted at large. Firstly, this article starts with the research on the present knowledge management and the analysis of different views, discussing the system framework, connotation and extension of knowledge management with systemic viewpoint. Then the paper will develop a knowledge management framework model and propose a system framework of knowledge management system and its practical application.
- Published
- 2008
12. Study on Knowledge Acquisition of the Telecom Customers' Consuming Behaviour Based on Data Mining
- Author
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Chunfang Zhao, Haijun Gao, and Ying-Liang Wu
- Subjects
Customer knowledge ,Voice of the customer ,Customer retention ,business.industry ,computer.software_genre ,Customer advocacy ,Customer Service Assurance ,Customer reference program ,Data mining ,Customer intelligence ,Telecommunications ,business ,Customer to customer ,computer - Abstract
As the reform development of telecom industry and the entrance of WTO, the competition among the telecom enterprises is becoming tougher. Nowadays, "customer-oriented" is the new principle of telecom market competition. As the enterprises in telecom industry have much more customers and customer data than those in other industries, the application of customer relationship management (CRM) in telecom industry becomes one of the hottest topics on enterprise informationlization. The thesis discusses the discovery of telecom customer knowledge based on data-mining. In this paper, a customer analysis model is founded by the method of data mining, including customer segmentation analysis, customer churn analysis, customer owing and fraud analysis. In the end, the thesis introduces a real case of a customer segmentation project in a mobile communication company and illustrates the application detail of customer intelligence in this company. In this case, the author uses SPSS Clementine to conduct data-mining. Meanwhile, diverse marketing strategy is also proposed based on the customer segmentation knowledge.
- Published
- 2008
13. Research on the Model of Knowledge Audit
- Author
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Ying-Liang Wu and Yi-Hua Li
- Subjects
Strategic planning ,Knowledge management ,business.industry ,Computer science ,Knowledge value chain ,Audit ,Intellectual capital ,Knowledge-based systems ,Workflow ,Internal audit ,Organizational learning ,Personal knowledge management ,Information technology audit ,business - Abstract
Knowledge management (KM) system includes KM strategic planning, technique, culture foundation, knowledge resource, process of knowledge transformation and exterior circumstance. Whether the definitude of KM stratagem or the early requirement design of KM implement, it must to evaluate the KM performance, to audit the KM requirement and program and to fulfill the KM process positive and feedback closed loop system. Organizations can set down KM strategy and programming and implement effectively no other than understanding its own knowledge stock, processes and requirement; can optimize KM no other than timely evaluating and auditing KM. This article introduce the concept of knowledge capital which root in intellectual capital as the object of the knowledge audit, thus the research fruit of intellectual capital could be used to study knowledge audit. Based on that, this article put forwards the integrity conception of KM audit, constitutes a conception model of knowledge audit and presents the workflow and currently methods of implementing knowledge audit.
- Published
- 2008
14. A Management Object Oriented Solution of Knowledge Management System
- Author
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Bo Zhou and Ying-Liang Wu
- Subjects
Information management ,Structure of Management Information ,Knowledge management ,Computer science ,business.industry ,Data management ,Knowledge engineering ,Knowledge value chain ,Risk management information systems ,Document management system ,Mathematical knowledge management ,computer.software_genre ,Knowledge-based systems ,Knowledge extraction ,Knowledge base ,Organizational learning ,Personal knowledge management ,Information system ,Domain knowledge ,business ,Management process ,computer ,Digital firm - Abstract
With the development of information system, there is an urgent need for enterprises to change from information management to knowledge management. In the network-computing environment, enterprises need to apply the complex, dynamic and integrated, object-oriented knowledge management system. First, this paper analyzed the essence of knowledge and knowledge management, discussed the concept and characteristics of enterprise knowledge portal. On this basis, the article proposed a management object oriented solution of knowledge management system, focusing on the framework of the system, mode of operation and the value of application with a case study. Such a solution can help enterprises to establish open, dynamic and integrated information and knowledge management systems.
- Published
- 2008
15. A Fuzzy Information Retrieval Method Based on the Vector-Correlative Model
- Author
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Ying-liang Wu and Bo Zhou
- Subjects
Structure (mathematical logic) ,Computer science ,business.industry ,Fuzzy set ,Knowledge engineering ,Information processing ,Construct (python library) ,computer.software_genre ,Machine learning ,Fuzzy logic ,Algorithm design ,Data mining ,Artificial intelligence ,Precision and recall ,business ,computer - Abstract
The VCM (Vector-Correlative Model) is one of the currently popular models for information searching. In this paper, author inducted Fuzzy Sets theory and approach for to construct information searching models, and presented a new VCM, which is called Fuzzy Vector-correlative Model (FVCM). So, its theory structure and user's searching quizzing mode has been dimming improved. We have show with some fringe experimentation that the new model has overcome some intrinsic defects of the exciting ones, and has raised the precision and recall of information search system.
- Published
- 2008
16. A Research of Value-Net Based Business Model and Operating of M-Commerce
- Author
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Haosu Wu, Chin E. Lin, and Ying-Liang Wu
- Subjects
Engineering management ,Process modeling ,Process management ,Electronic business ,New business development ,Artifact-centric business process model ,Mobile business development ,Consumer-to-business ,Business ,Business process modeling ,Business model - Abstract
Recent advances in Internet and e-commerce have led industry to reengineer their organizational structures and value chains. One of the most prominent trends in this change is to conduct work and operation in the distributed or virtual environments. A new kind of business model, termed as value-net, is emerging. In this paper, the business and system mode from the value-net system is studied and proposed. The feature of this business model suitable for Mobile Commerce (M-Commerce) is analyzed on the basis of value-net. The ecosystems (ecology system) model based on value-net is presented for the M-Commerce with systematic structure, collaborate mode and working mechanism. A modified value-net based ecosystem for M-Commerce operators is proposed in this paper with practical case analysis.
- Published
- 2007
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