Author: "YANG Jing" / Topic: business - Searchworks@Jio Institute Digital Library Search Results

479 results on '"YANG Jing"'

1. Competitive Advantages and Values Created and Attained Out of Well-Crafted Customer Value Propositions

Author: Forrest Jeffrey Yi-Lin, Novikov Dmitry A., Larson Stephen, Wang Fen, and Yang Jing
Subjects: cash flow, market invitation, mission, operating process, value added, Business, HF5001-6182
Abstract: To help facilitate the development of a theoretically rigorous and practically useful theory of customer value propositions (CVP), as called for repeatedly by the extant literature, this paper establishes a game-theoretic theorem regarding the dynamics of market competition and potential market entry. On top of this result and by employing logical rigor and analytical reasoning, eight generally true facts are developed without suffering from the constraints of data- and anecdote- based approaches, as widely used in the literature. In particular, these established results reveal how a newly adopted CVP is associated with the three essential processes underlying a company’s operation, how it will be pivotal for the company to attain competitive advantages, how the value added by adopted CVPs can be determined, etc. At the end, recommendations for decision-making managers and entrepreneurs and potential questions for future research are provided.
Published: 2021
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2. The effects of a schizophrenia pay-for-performance program on patient outcomes in Taiwan

Author: Chen, Tsung-Tai, Yang, Jing-Jung, Hsueh, Ya-seng, and Wang, Vinchi
Subjects: National health insurance, Schizophrenia -- Patient outcomes, Psychiatric hospitals, Employee performance, Insurance, Business, Health care industry
Abstract: Objective: To examine the effects of a schizophrenia pay-for-performance (P4P) program on the health outcomes of patients in Taiwan. Data Sources: Seven years (2007-2013) of data from the National Health Insurance Administration (NHIA) databases were examined. Study Design: P4P patients included those who were treated at participating facilities and consecutively included in the regular group (classified by the NHIA). Non-P4P patients were treated at nonparticipating facilities and never included in the regular group. The caliper matching method and a generalized estimating equation were used to estimate difference-in-differences models (baseline year 2009) and examine the short- and long-term effects of the P4P program on adverse outcomes. Principal Findings: The schizophrenia P4P program was associated with decreases in unscheduled outpatient visits (OR: 0.69, P < 0.001) and compulsory admissions (incidence rate ratio: 0.33, P < 0.05). However, this program was not associated with decreases in other outcomes including emergency department visits for any disease, admissions to an acute psychiatric ward, and readmission within 6 months. Conclusions: Although the disease management component of the P4P program can be beneficial for compulsory admissions, more sophisticated activities, such as health promotion targeting disadvantaged patients, could be implemented to reduce the occurrence of complicated adverse outcomes. KEYWORDS compulsory admission, disease management program, pay-for-performance, readmission, schizophrenia, 1 | OBJECTIVE Scientific evidence examining the effects of pay-for-performance (P4P) in behavioral health care is scarce. (1) Taiwan introduced a schizophrenia P4P program in 2010 that has four components. [...]
Published: 2019
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3. Complex non-diffraction beams generated using binary computational holography

Author: Huang Wen-jun, XU Fu-yang, Ren Zhi-jun, and Yang Jing-yu
Subjects: Diffraction, Materials science, Optics, law, business.industry, Holography, Binary number, business, Atomic and Molecular Physics, and Optics, law.invention
Published: 2022

4. Predicting soluble solids content in 'Fuji' apples of different ripening stages based on multiple information fusion

Author: Zhenhui Ren, Huang Yirui, Juan Wang, Yang Jing, and Na Li
Subjects: Channel (digital image), business.industry, Multispectral image, Hyperspectral imaging, Pattern recognition, Ripening, Color space, Autoencoder, Artificial Intelligence, Signal Processing, Content (measure theory), RGB color model, Computer Vision and Pattern Recognition, Artificial intelligence, business, Software, Mathematics
Abstract: Soluble solids content (SSC) is one of the important components for the assessment of fruit quality. Near-infrared (NIR) spectroscopy, multispectral and hyperspectral imaging techniques are widely used methods for the SSC estimation. However, the high prices are unaffordable for small commercial orchards. The objective of this work is to present a computer vision system for the SSC estimation of “Fuji” apples in different ripening stages. Multiple information of the color channels (channel a* and channel b*) in L*a*b* color space translated from RGB images were applied to extract color features. Stacked autoencoder (SAE) algorithm was used to extract color features in pixel-level, and the trained parameters were used as the initial parameters of the prediction model by using back propagation neural network (BPNN) algorithm. The results show that the prediction accuracy of the SAE-BPNN model based on color features in pixel-level is higher than that of the BPNN model based on pure color features in feature-level. Moreover, the model with fusion information of both color channels as inputs can get better prediction results than that of single channel. The SAE-BPNN model with SAE structure of 270-120-30 yielded the best result with R p 2 = 0.5953 and RMSEP = 0.8856%. This research indicates that RGB imaging technology based on multiple information has potential for the SSC prediction, which provides reference values for fruit harvesting and non-destructive evaluation of fruit quality.
Published: 2021

5. Successful treatment of gastrointestinal infection-induced septic shock using the oXiris® hemofilter: A case report

Author: Yu Li, Dan-Yang Jing, Zheng-Hui Huang, Mei-Li Duan, and Xiao-Jun Ji
Subjects: Continuous renal replacement therapy, business.industry, Infection induced, Septic shock, oXiris®, Acute kidney injury, General Medicine, medicine.disease, Sepsis, Anesthesia, Case report, Medicine, business
Abstract: BACKGROUND Septic shock leads to multiple organ failure, and bacterial endotoxins and endogenous cytokines play essential roles in the pathogenesis. The oXiris® hemofilter can efficiently adsorb endotoxins and cytokines. CASE SUMMARY We admitted a critically ill 59 year-old male patient with gastrointestinal septic shock due to infection by a Gram-negative bacterium and septic acute kidney injury (AKI). Prior to intensive care unit admission, the patient reported intermittent diarrhea and decreased urine output. His blood pressure was 70/40 mmHg, necessitating fluid resuscitation and large doses of noradrenaline. Based on the results of a blood culture and the presence of hypotension, oliguria, and hypoxemia, we diagnosed septic shock, AKI, and multiple organ dysfunction. We administered continuous renal replacement therapy (CRRT) with an oXiris® hemofilter for 72 h with intermittent continuous veno-venous hemodiafiltration (CVVHDF), and changed the filter every 12 h. After his hemodynamic parameters were stable, we used a traditional filter (AN69 hemofilter) with intermittent CVVHDF. The 72 h CRRT with the oXiris® hemofilter led to stabilization of his vital signs, marked reductions in disease severity scores, and decreased levels of procalcitonin, endotoxin, and inflammatory factors. After 8 d of CRRT, his kidney function had completely recovered. CONCLUSION We conclude that the oXiris® hemofilter combined with appropriate antibacterial therapy was an effective treatment for this patient with gastrointestinal septic shock.
Published: 2021

6. Mixed bacterial-fungal infection following total hip arthroplasty: A case report

Author: Yang-Jing Lin, Tiao Su, Liu Yang, and Guang-xing Chen
Subjects: Medicine (General), medicine.medical_specialty, Staphylococcus hominis, medicine.medical_treatment, Periprosthetic, Case Report, Arthroplasty, R5-920, Candida albicans, Medicine, Orthopedics and Sports Medicine, Prosthesis-Related Infection, Pathogen, Femoral neck, Debridement, Hip, biology, business.industry, biology.organism_classification, Surgery, medicine.anatomical_structure, Prosthesis-related infections, business
Abstract: Prosthetic infection is one of the severe postoperative complications of arthroplasty. Mixed bacterial-fungal prosthetic infection is rare but can be disastrous. This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements. The culture of periprosthetic tissue was bacteriologically sterile following the first debridement, while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered. Thus the pathogen spectrum of anti-infection therapy failed to contain fungus. Ultimately, the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital. The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs. Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty, especially for mixed bacterial-fungal prosthetic infection.
Published: 2021

7. R/S Ratio in Lead III Predicts Successful Ablation of Ventricular Arrhythmias Originating in Para-Hisian Region

Author: Pan Yang-Qi, Lin Jia-Xuan, Lin Yuan-Nan, Li Yue-Chun, Lin Jia-Feng, Xue Yang-Jing, Xu Jing, Zheng Cheng, Li Jia, and Li Jin
Subjects: Bundle of His, medicine.medical_specialty, business.industry, medicine.medical_treatment, Significant difference, Arrhythmias, Cardiac, Catheter ablation, 030204 cardiovascular system & hematology, Ablation, medicine.disease, Electrocardiography, 03 medical and health sciences, QRS complex, 0302 clinical medicine, Internal medicine, Catheter Ablation, medicine, Cardiology, Humans, 030212 general & internal medicine, Lead (electronics), business, Atrioventricular block, Retrospective Studies
Abstract: Objectives The aim of this study was to investigate the electrocardiographic characteristics of ventricular arrhythmias (VAs) originating near the His bundle (HB) and use the R/S ratio in lead III (RIII/SIII ratio) to predict successful ablation of para-Hisian VAs. Background Catheter ablation for idiopathic VAs near the HB is often challenging, and data are limited. Methods The present study included 134 consecutive patients undergoing catheter ablation of para-Hisian VAs. The electrocardiographic characteristics in these patients were retrospectively evaluated with successful ablation and failed ablation. Results Successful ablation was achieved in 115 (85.8%) of the 134 patients. There was no significant difference in QRS duration between the successful and the failed ablation groups. The ablation success rate was significantly lower for para-Hisian VAs with a predominantly positive R wave in lead III than those with a predominantly negative S wave in lead III. The significant factor associated with successful ablation was the RIII/SIII ratio. The RIII/SIII ratio ≤1.1 predicted the successful ablation of para-Hisian VAs with high sensitivity (80.9%) and specificity (94.7%). The RIII/SIII ratio of >1.2 had high sensitivity (100.0%) and specificity (82.8%) to predict the distance Conclusions The RIII/SIII ratio was a helpful predictor of the successful ablation of VAs originating in the vicinity of the HB. This may be useful for planning ablation of para-Hisian VAs and minimizing the risk of inadvertent atrioventricular block.
Published: 2021

8. Hospital antibiotic prescribing patterns in adult patients according to the WHO Access, Watch and Reserve classification (AWaRe): results from a worldwide point prevalence survey in 69 countries

Author: Pauwels, Ines, Versporten, Ann, Drapier, Nico, Vlieghe, Erika, Goossens, Herman, Koraqi, Andi, Hoxha, Iris, Tafaj, Silva, Cornistein, Wanda, Quiros, Rodolfo, Hojman, Martin, Ghazaryan, Lilit, Horne, Kylie, Cairns, Kelly, Doukas, Fiona, Gottlieb, Thomas, Sermijn, Erica, Verhamme, Katia, Brands, Christiane, Van Herendael, Bruno, Filippin, Lorenzo, Vandewal, Wouter, Konopnicki, Deborah, Maillart, Evelyne, Teixeira Lopes, Liliana, Papin, Pauline, Smits, Ilse, Jansens, Hilde, Bartholomeus, Sofie, Van den Abeele, Anne-Marie, Steyaert, Sophia, Piette, Anne, Buyle, Franky, Cartuyvels, Reinoud, Jonckheere, Stijn, Wybo, Ingrid, Vanneste, Lorenz, Mathieu, Delphine, Firre, Eric, Westelinck, Veerle, Gadisseux, Philippe, Dugernier, Thierry, Bafort, Kristof, Gonissen, Viviane, Vanderper, Vanessa, Gabriels, Patrick, Weekers, Frank, Michel, Philippe, Van Liedekerke, Ann, Costers, Michiel, Catry, Boudewijn, Dedeic-Ljubovic, Amela, Gales, Ana C., Matos Porto, Ana Paula, Figueiredo Costa, Silvia, Keuleyan, Emma, Beidi, Apollinaire, Cissohko, Youssouph, Blakwe, Habsatou, Batchaya Basile, Ngassa, German, Greg J., Lutes, Sarah, Boswell, Jennifer, Mertz, Dominik, Nguyen, Tuyen, MacLaggan, Timothy, Landry, Daniel, Ang, Anita, Thirion, Daniel J.G., Frenette, Charles, Émond, Yannick, Roberts, Jacqueline, Chang, Sandra, Kosar, Justin, Valiquette, Louis, Dutrisac, Ginette, Afra, Kevin, McGeer, Allison, Carrier, Marie, Grant, Jennifer, Labarca, Jaime, Carvajal, Camila, Lin, HongYi, Wang, Qiang, Yang, Jing, Yang, Wenjie, Cortes, Jorge A., Villalobos-Vindas, Juan, Ramírez-Valverde, Carlos, Horvatic, Jasminka, Pristas, Irina, Paphitou, Niki, Rummukainen, Maija-Liisa, Froissart, Antoine, Vanhems, Philippe, Pagava, Karaman, Korinteli, Irma, Brandt, Tobias, Gaertner, Johannes, Enimil, Anthony, Roilides, Emmanuel, Hajdú, Edit, Sengupta, Sharmila, Singh, Sanjeev, Patil, Priyanka, Poojary, Aruna, Soltani, Jafar, Pouladfar, Gholamreza, Jafarpour, Zahra, Alinia, Cyrus, Ameen, Hadi, Fitzgerald, David, Paul, Mical, Maor, Yasmin, Strahilevitz, Jacob, Chowers, Michal, Temkin, Elizabeth, Luca, Arnoldo, Ishibashi, Noriomi, Gu, Yoshiaki, Darwish Elhajji, Feras, Karabukayeva, Aizhan, Raka, Denis, Kambaralieva, Baktygul, Zarakauska, Lelde, Zarb, Peter, Hernandez Chena, Blanca Estela, Gonzalez-Diaz, Esteban, Corona-Meléndez, JuanCarlos, Torres Erazo, Darwin Stalin, Loza-Jalil, Suria Elizabeth, Molina, Julio, Candelas, Jose Antonio, Mijovic, Gordana, Duborija-Kovacevic, Natasa, Jong, Eefje, Kluytmans, Jan, van Elzakker, Erika, Schweitzer, Valentijn, Davies, Nicola, Iregbu, Kenneth, Nwajiobi-Princewill, Philip, Nwafia, Ifeyinwa, Fasuyi, Temitayo, Aboderin, Aaron, Elikwu, Charles John, Fadeyi, Abayomi, Ola-Bello, Olafoyekemi, Oduyebo, Oyinlola, Adedosu, Akin Nelson, Ekuma, Agantem, Shaqiri, Erjona, Saleem, Zikria, De Los Reyes, Mari Rose, Tavares, Luis, Kim, Nam Joong, Rachina, Svetlana, Alharthi, Alwaleed R., Enani, Mushira, Faried, Osama, Mirghani, Mohamed, Carevic, Biljana, Radulovic, Lili, Dragovac, Gorana, Tan, Sock Hoon, Taljaard, Jantjie, Chibabhai, Vindana, Joiner, Jennifer, Caston, Juan Jose, Núñez-Núñez, María, Martínez-Marcos, Francisco Javier, Ojeda-Burgos, Guillermo, Menendez, Maria Dolores, Retamar, Pilar, Corzo, Juan E., Rattanaumpawan, Pinyo, Salou, Mounerou, Mnif, Basma, Oncul, Ahsen, Babigumira, Peter Ahabwe, Olweny, James, Marshall, Emily, McCorry, Ann, Aldeyab, Mamoon, Khanna, Priya, Gormley, Cairine, Maloney, Sara, Cooper, Mandelin, Blackburn, Laura, Gessner-Wharton, Mallory, Vu, Lam, Greer, Nickie, Gawrys, Gerard, Kronmann, Lisha, Rios, Edgar, Hudson, Melissa, Lindholm, David A., The Global-PPS network, Vriendenkring VUB, Clinical sciences, Microbiology and Infection Control, and Clinical Biology
Subjects: Adult, Microbiology (medical), Point prevalence survey, Latin Americans, education, Population, MEDLINE, World Health Organization, Essential medicines, Antibiotic prescribing, Anti-Infective Agents, Environmental health, Prevalence, Humans, AcademicSubjects/MED00740, Medicine, Pharmacology (medical), Medical prescription, Biology, Original Research, Pharmacology, education.field_of_study, Adult patients, business.industry, Pharmacology. Therapy, Hospitals, Anti-Bacterial Agents, Anti-Bacterial Agents/therapeutic use, AcademicSubjects/MED00290, Infectious Diseases, Human medicine, AcademicSubjects/MED00230, business
Abstract: ObjectivesThe WHO Access, Watch and Reserve (AWaRe) classification has been developed to support countries and hospitals in promoting rational use of antibiotics while improving access to these essential medicines. We aimed to describe patterns of worldwide antibiotic use according to the AWaRe classification in the adult inpatient population.MethodsThe Global Point Prevalence Survey on Antimicrobial Consumption and Resistance (Global-PPS) collects hospital antibiotic use data using a standardized PPS methodology. Global-PPS 2015, 2017 and 2018 data, collected by 664 hospitals in 69 countries, were categorized into AWaRe groups to calculate proportional AWaRe use, Access-to-Watch ratios and the most common indications for treatment with selected Watch antibiotics. Only prescriptions for systemic antibiotics on adult inpatient wards were analysed.ResultsRegional Access use ranged from 28.4% in West and Central Asia to 57.7% in Oceania, whereas Watch use was lowest in Oceania (41.3%) and highest in West and Central Asia (66.1%). Reserve use ranged from 0.03% in sub-Saharan Africa to 4.7% in Latin America. There were large differences in AWaRe prescribing at country level. Watch antibiotics were prescribed for a range of very different indications worldwide, both for therapeutic and prophylactic use.ConclusionsWe observed considerable variations in AWaRe prescribing and high use of Watch antibiotics, particularly in lower- and upper-middle-income countries, followed by high-income countries. The WHO AWaRe classification has an instrumental role to play in local and national stewardship activities to assess prescribing patterns and to inform and evaluate stewardship activities.
Published: 2021

9. The effect of psychological condition before radiotherapy on prognosis in 390 patients initially treated for nasopharyngeal carcinoma

Author: Xiurong Song, Jinru Ye, Jun Tian, Caihong Wang, Yang-Jing-Ling Hua, Rong Li, Li Su, Jinmei Chen, Hai-Rong Zhang, Weijian Zhang, and Jinsheng Hong
Subjects: Oncology, medicine.medical_specialty, medicine.medical_treatment, Hospital Anxiety and Depression Scale, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Survival rate, Depression (differential diagnoses), Survival analysis, Neoplasm Staging, Retrospective Studies, Nasopharyngeal Carcinoma, business.industry, Proportional hazards model, Nasopharyngeal Neoplasms, Prognosis, medicine.disease, Radiation therapy, Nasopharyngeal carcinoma, 030220 oncology & carcinogenesis, Anxiety, Radiotherapy, Intensity-Modulated, medicine.symptom, business
Abstract: To explore whether anxiety and depression are prognostic indexes for overall survival in patients with nasopharyngeal carcinoma (NPC) who underwent intensity-modulated radiotherapy (IMRT). Clinical data were collected for NPC patients who underwent IMRT. Anxiety and depression were investigated before radiotherapy by using the Hospital Anxiety and Depression Scale (HADS). The survival rate was calculated by the Kaplan-Meier method, and survival curves were compared among patients with different levels of anxiety and depression. The Cox risk regression model was used to screen the factors affecting survival. A total of 390 initially treated NPC patients were included in the study. Among them, 166 patients suffered from anxiety, and 95 patients suffered from depression before radiotherapy. The 5-year overall survival rates for patients with and without anxiety before radiotherapy were 71.6% and 81.8% (χ2 = 5.31, P = 0.021), respectively. The 5-year overall survival rates for patients with and without depression before radiotherapy were 74.3% and 78.1% (χ2 = 0.05, P = 0.82), respectively. Cox regression analysis indicated clinical stages (HR = 3.982, 95% CI: 2.365~6.705), anxiety (HR = 1.832, 95% CI: 1.140~2.944), and gender (HR = 0.555, 95% CI: 0.313~0.984) as independent prognostic factors. Anxiety before radiotherapy is associated with poor prognosis in NPC patients.
Published: 2021

10. Hyperconnection and hyperperfusion of overlapping brain regions in patients with menstrual-related migraine: a multimodal neuroimaging study

Author: Wutao Lou, Ahsan Khan, Ganqin Du, Jin Xu, Yang Jing, Li Xinyu, Yingying Li, Raymond Kai-Yu Tong, Zhan Haohui, and Diansen Chen
Subjects: medicine.medical_specialty, Neurology, Migraine Disorders, Neuroimaging, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Ictal, Neuroradiology, medicine.diagnostic_test, business.industry, Brain, medicine.disease, Magnetic Resonance Imaging, Cerebral blood flow, Migraine, Cerebrovascular Circulation, Cardiology, Female, Neurology (clinical), Headaches, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Functional magnetic resonance imaging, 030217 neurology & neurosurgery
Abstract: Menstrual-related migraine (MRM) results in moderate to severe intensity headaches accompanied by physical and emotional disability over time in women. Neuroimaging methodologies have advanced our understanding of migraine; however, the neural mechanisms of MRM are not clearly understood. In this study, fourteen MRM patients in the interictal phase and fifteen age- and education-matched healthy control females were recruited. Resting-state functional magnetic resonance imaging (fMRI) and pulsed arterial spin labeling (PASL) MRI were collected for both the subject groups outside of their menstrual periods. Eigenvector centrality mapping (ECM) was performed on resting-state fMRI, and the relative cerebral blood flow (relCBF) was assessed using PASL-MRI. MRM patients showed a significantly increased eigenvector centrality in the right medial frontal gyrus compared to healthy controls. Seed-based ECM analysis revealed that increased centrality was associated with the right medial frontal gyrus’s hyperconnectivity with the left insula and the right supplementary motor area. The perfusion MRI revealed significantly increased relCBF in the hyperconnected regions. Furthermore, the hyperconnection positively correlated with the attack frequency, while the hyperperfusion showed a positive correlation with the disease duration. The results suggest that menstrual-related migraine is associated with cerebral hyperconnection and hyperperfusion in critical pain-processing brain regions. Furthermore, this elevated cerebral activity is correlated with different aspects of functional impairment in MRM patients suggesting that perfusion analysis, along with whole-brain connectivity analysis, can provide a comprehensive understanding of neural mechanisms of MRM.
Published: 2021

11. Application Prospect of CAD-SketchUp-PS Integrated Software Technology in Landscape Planning and Design

Author: Yang Jing and Yang Song
Subjects: Computational Mathematics, Engineering, business.industry, Integrated software, Computational Mechanics, CAD, Software engineering, business, Computer Graphics and Computer-Aided Design, Landscape planning
Abstract: e current landscape design, comprehensive software has been widely used in the current landscape design. For landscape design, the use of modern high-tech technology has become a new trend of vigorous development of auxiliary landscape planning and design. Therefore, from the drawing of CAD plan to the creation of SketchUp model, and then to the PS processing of the effect drawing, not only can the landscape planning designers more intuitive and in-depth creative ideas, but also the best way to show the landscape. This paper briefly introduces CAD, SketchUp and PS, analyzes the application process and file transfer of CAD SketchUp PS software in landscape planning and design, and comprehensively expounds the application skills and application prospects of CAD SketchUp PS software in landscape design.
Published: 2020

12. Thermo-mechanical analysis of train wheel-rail contact using a novel finite-element model

Author: Hu Ming, Deming Zhao, Xun Zhou, Yang Jing, and Yang Liuqing
Subjects: Alternative methods, Materials science, business.industry, Mechanical Engineering, Structural engineering, Finite element method, Surfaces, Coatings and Films, General Energy, Residual stress, Head (vessel), Trailing edge, Tread, Fe model, business, Thermo mechanical
Abstract: Purpose The purpose of this paper is to develop a novel method for analyzing wheel-rail (W-R) contact using thermo-mechanical measurements and study the effects of heating on the characteristics of W-R contact under different creepages. Design/methodology/approach This study developed an implicit-explicit finite element (FE) model which could solve both partial slip and full sliding problems by setting different angular velocities on the wheels. Based on the model, four material types under six different creepages were simulated. Findings The results showed that frictional heating significantly affected the residual stress distribution under large creepage conditions. As creepage increased, the temperature of the wheel tread and rail head rose and the peak value was located at the trailing edge of the contact patch. Originality/value The proposed FE model could reduce computational time and thus cost to about one-third of the amount commonly found in previous literature. Compared to other studies, these results are in good agreement and offer a reasonable alternative method for analyzing W-R contact under various conditions. Peer review The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-07-2019-0298
Published: 2020

13. Design of a Multi-functional Device Based on the Solid-state Plasma: Absorber and Splitter

Author: Yang Jing, Zhang Hao, and Haifeng Zhang
Subjects: Materials science, Absorption spectroscopy, business.industry, Biophysics, Reflector (antenna), 02 engineering and technology, Plasma, 021001 nanoscience & nanotechnology, 01 natural sciences, Biochemistry, 010309 optics, Electric field, Splitter, 0103 physical sciences, Metamaterial absorber, Optoelectronics, 0210 nano-technology, business, Absorption (electromagnetic radiation), Computer Science::Databases, Beam (structure), Biotechnology
Abstract: We propose a multi-functional device by using the solid-state plasma, which can be called a plasma metamaterial absorber (PMA). The absorber can get tunable absorption spectrum by exciting different solid-state plasma resonance units. The common absorption frequency region of TE and TM waves can span from 1.7162 to 3.997 THz, whose absorption rate is is than 90%. The simulations also demonstrate that when the excited solid-state plasma resonance units are different, different operating states can be realized. The proposed PMA not only can be seen as an absorber but also can be considered as a reflector or a polarization splitter under different operating states. Moreover, by investigating the surface current, electric field, and energy loss, the physical mechanism of absorption of this PMA can be figured out, which is the magnetic resonance. Such a device also can potentially act as a space beam compiler.
Published: 2020

14. Hot pressing of wood-based composites: a review

Author: Wei, Peixing, Rao, Xin, Yang, Jing, Guo, Yeyingzi, Chen, Huimin, Zhang, Yue, Chen, Shihui, Deng, Xi, and Wang, Zheng
Subjects: Plywood construction -- Analysis, Mass transfer -- Analysis, Business, Forest products industry
Abstract: Abstract The hot-pressing process is a vital step in the manufacture of wood-based composites and directly affects the properties and quality of the final products. During hot pressing, the heat [...]
Published: 2016
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15. Associations of visit-to-visit variabilities and trajectories of serum lipids with the future probability of type 2 diabetes mellitus

Author: Lei Wu, Hui Zhou, Yang Jing, Chen Dong, Qian Sun, Yue Sun, Jianrong Jin, Jingchao Liu, Sudan Wang, and Jing Wu
Subjects: Male, medicine.medical_specialty, RC620-627, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Trajectory, Blood lipids, Association, Endocrinology, Risk Factors, Internal medicine, Type 2 diabetes mellitus, medicine, Humans, Serum lipids, Prediabetes, Risk factor, Nutritional diseases. Deficiency diseases, Triglycerides, Probability, Proportional Hazards Models, business.industry, Proportional hazards model, Incidence (epidemiology), Research, Biochemistry (medical), Hazard ratio, nutritional and metabolic diseases, Middle Aged, medicine.disease, Lipids, Confidence interval, Lipoproteins, LDL, Cholesterol, Quartile, Diabetes Mellitus, Type 2, Female, Visit-to-visit variability, business, Lipoproteins, HDL
Abstract: Background Serum lipid abnormalities are generally considered as a major risk factor for type 2 diabetes mellitus (T2DM). However, evidence for the effect of long-term serum lipid fluctuations on future T2DM probability remains limited. Methods A total of 4475 nondiabetic participants who underwent annual health examinations between 2010 and 2013 were followed for the subsequent 5-year risk of T2DM. The Cox proportional hazards model was performed to evaluate the associations of visit-to-visit variabilities and trajectories of triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) with T2DM probability. Results During the five-year follow-up, 223 newly developed T2DM cases were identified. Compared with the “Low” TG trajectory, “Moderate” and “Moderate-High” TG trajectories were significantly associated with T2DM incidence, with adjusted hazard ratios (HRs) and 95 % confidence intervals (CIs) of 1.51 (1.12-2.03) and 2.55 (1.62-4.03), respectively. Additionally, participants in the third and fourth quartiles of TG/standard deviation (SD) were associated with increased T2DM probability when compared with those in the lowest quartile. After excluding individuals with prediabetes, participants with “Moderate-High” TG trajectory still had a 2.43-fold greater risk of T2DM compared with those with “Low” TG trajectory (95 % CI: 1.28-4.63). In addition, compared with participants in “Low” HDL-c trajectory, the future T2DM probability was significantly reduced in those with “Moderate” and “High” HDL-c trajectories, with HR (95 % CI) of 0.52 (0.37-0.72) and 0.38 (0.18-0.80), respectively. After excluding individuals with prediabetes, the “Moderate” HDL-c trajectory remained associated with decreased T2DM probability when compared with “Low” HDL-c trajectory (HR: 0.55, 95 % CI: 0.35-0.88). However, the incidence of T2DM was not associated with the long-term fluctuations of TC and LDL-c. Conclusions Long-term visit-to-visit variability of TG, and the change trajectories of TG and HDL-c were significantly associated with future T2DM probability. Moreover, these associations were not affected after excluding individuals with prediabetes.
Published: 2021

16. Lumen and Media-Adventitia Border Detection in Intravascular Ultrasound Using a Coarse-to-fine Annotation Strategy

Author: Peng Song, Yang Jing, and Junbo Li
Subjects: medicine.diagnostic_test, Computer science, business.industry, Deep learning, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Image segmentation, Convolutional neural network, Annotation, Automatic image annotation, Intravascular ultrasound, medicine, Medical imaging, Computer vision, Segmentation, Artificial intelligence, business
Abstract: Detection of lumen and media-adventitia (MA) borders in intravascular ultrasound (IVUS) image has long been investigated by medical imaging researchers. Recent progress in convolutional neural network (CNN) shows marked improvement of image segmentation performance comparing with traditional methods, and has been successfully applied to IVUS. Deep learning based image segmentation requires significant amount of annotated data. However, image annotation for semantic segmentation is tedious and time-consuming. In this study, we proposed a coarse-to-fine strategy to facilitate image annotation and employed BASNet architecture for IVUS lumen and MA border detection. Results on 34 patient data show high annotation efficiency with mean intersection over union (IoU) of 0.927.
Published: 2021

17. Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels

Author: Wang Yongqi, Yang Jing, Tang Yiting, Li Yinghao, Zhou Jianming, Li Shuoqi, and Gao Zeng
Subjects: Male, medicine.medical_specialty, Medicine (General), insulin-like growth factor 1, medicine.medical_treatment, Growth hormone, Biochemistry, Blood flow restriction, Pre-Clinical Research Report, Insulin-like growth factor, R5-920, Internal medicine, Humans, Medicine, Single-Blind Method, Insulin-Like Growth Factor I, Exercise, Testosterone, myogenic hormone, Human Growth Hormone, business.industry, Growth factor, Biochemistry (medical), Resistance training, Serum growth hormone, Cell Biology, General Medicine, resistance exercise, cuff pressure, Endocrinology, Growth Hormone, testosterone, Cuff, business
Abstract: Objective To investigate the changes in serum growth hormone (GH), testosterone, and insulin-like growth factor 1 (IGF-1) during low-intensity resistance exercise under different cuff pressures. Methods We performed a single-blind, cross-over design study. Twenty-five healthy young men performed three exercise protocols as follows: 1) no blood flow restriction exercise (control group), 2) resistance exercise at 40% of arterial occlusion pressure (AOP) (low group), and 3) resistance exercise at 70% of AOP (high group). Blood lactate, GH, testosterone, and IGF-1 levels were measured at four time points. Results There were no differences in the indices before exercise. The blood flow restriction exercise under different pressures had different effects on each index and there was an interactive effect. GH levels were significantly higher in the high group than in the other groups after exercise. Immediately after exercise, IGF-1 and testosterone levels were significantly higher in the high group than in the other groups. At 15 minutes after exercise, testosterone levels were significantly higher in the high group than in the other groups. Conclusions Low-intensity resistance exercise combined with blood flow restriction effectively increases GH, IGF-1, and testosterone levels in young men. Increasing the cuff pressure results in greater levels of hormone secretion.
Published: 2021

18. Design and Implementation of Environment Monitor for Urban Rail Transit

Author: Li Jun, Zhang Haoran, Tian Qing, Wang Lu, and Yang Jing
Subjects: Signal processing, Urban rail transit, business.industry, Miniaturization, STM32, System integration, Environmental science, Wind direction, business, Chip, Wind speed, Automotive engineering
Abstract: In order to monitor the gas of urban rail transit station in real time and effectively, this paper designs a real-time multi-element integrated real-time monitor based on STM32 series chip, which combines the advanced signal processing technology, multi-sensor identification technology and system integration technology, aiming at the unique characteristics of micro environment of rail transit station, and integrates a variety of different modes of gas detection Sensors and weather sensors are integrated at chip level and device level to overcome the technical problems of integration, miniaturization and modularization. Real time monitoring and display of 10 gas parameters such as oxygen, carbon dioxide, carbon monoxide, sulfur dioxide and 5 meteorological parameters such as temperature, humidity, wind speed, air pressure and wind direction are realized.
Published: 2021

19. A Mixing and Separation Method of Signals + Color Images Based on Two-Dimensional CCA

Author: Chen Kexin, Fan Li-ya, and Yang Jing
Subjects: Data set, Signal processing, business.industry, Color image, Computer science, Pattern recognition (psychology), Pattern recognition, Artificial intelligence, business, Blind signal separation, Signal, Independence (probability theory), Mixing (physics)
Abstract: Blind Source Separation (BSS) is a traditional and challenging problem in signal processing, in which the mixed signals can be separated according to the independence of source signals. The one-dimensional CCA-based signal and color image mixing and separation method needs to reshape the image into vector data, which destroys the spatial structure of the image and affects the recovery effect of the color image. To this end, a mixing and separation method of signals + color images based on two-dimensional CCA, in this paper, is proposed. This method utilizes the auto-correlation among original color images and signals to recover signals and images with high qualities. Comparative experiments with one-dimensional CCA on the COIL-100 data set show that the proposed method is effective and high-speed.
Published: 2021

20. Vertical transmission potential of SARS-CoV-2 from infected mother to twin neonates

Author: Ashaq Ali, Liangyu Peng, Suliman Khan, Saeed Ahmed, Yang Jing, Guang Han, and Liaqat Ali
Subjects: 0301 basic medicine, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Obstetrics, business.industry, Transmission (medicine), Premature twins, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pregnancy outcomes, Transmission potential, Case Report, twins, Case description, COVID-19 infection, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Virology, medicine, vertical transmission, 030212 general & internal medicine, business, Intrauterine infection
Abstract: Background: Limited details are available regarding the vertical transmission potential of COVID-19 infection in pregnant women. The authors' current study aimed to report the vertical transmission potential of COVID-19 infection in a woman pregnant with twins. Case description: The authors report the case of a 27-year-old woman infected with SARS-CoV-2. The patient was pregnant with dichorionic diamniotic fraternal twins and admitted to Renmin Hospital of Wuhan University, Wuhan, China. After undergoing a cesarean section, the patient gave birth to premature twins, who tested positive for COVID-19 infection. Interpretation: Findings from this case suggest a possibility of intrauterine infection caused by vertical transmission in a woman infected with COVID-19.
Published: 2021

21. Seroprevalence and molecular characteristics of varicella-zoster virus infection in Chinese children

Author: Xiaochen Shen, Yang Jing, Jingqi Zhang, Jing Qiu, Jie Wang, Jun Zhang, Lin Luan, and Chen Dong
Subjects: Male, 0301 basic medicine, China, Herpesvirus 3, Human, medicine.medical_specialty, Pediatrics, Varicella vaccine, Genotype, viruses, 030106 microbiology, medicine.disease_cause, Virus, lcsh:Infectious and parasitic diseases, Chickenpox Vaccine, 03 medical and health sciences, 0302 clinical medicine, Medical microbiology, Seroepidemiologic Studies, medicine, Humans, Seroprevalence, lcsh:RC109-216, 030212 general & internal medicine, Child, Phylogeny, integumentary system, business.industry, Vaccination, Varicella zoster virus, virus diseases, Antibodies, Anti-Idiotypic, Infectious Diseases, Seroprevalence, vaccination, Parasitology, Immunization, Child, Preschool, Varicella Zoster Virus Infection, Varicella-zoster virus, Female, business, Research Article
Abstract: Background Varicella-zoster virus (VZV) infection in children is an important public health problem in China. We performed the current study to explore the seroprevalence of VZV infection in Chinese children in order to provide more information for improvement of varicella vaccination in China. Methods 3014 serum samples were collected from Chinese kindergarten students aged from four to six years. Anti-VZV IgG and IgM were assayed using enzyme-linked immunosorbent assay. Both ORF22 and ORF62 of VZV were amplified, sequenced, and analyzed by nested PCR. Results Totally, 43.9% of boys and 46.3% of girls were vaccinated with varicella vaccine, respectively. The seroprevalence of anti-VZV IgG was 54.4% in the children with varicella vaccination, which was significantly higher than those in unvaccinated children (49.2%) (χ2=8.206, P=0.004). Among of the vaccinated children, the detection rates of VZV IgG antibody increased with age, with 49.4%, 50.9% and 58.9% in 4, 5 and 6-year groups, respectively (Trend χ2=17.202, P=0.002). However, there was no difference in anti-VZV IgG detection rates among those unvaccinated children in different age groups (Trend χ2=8.681, P=0.070). In addition, thirteen boys and 13 girls were positive for anti-VZV IgM, respectively. Among of them, eight children (0.6%) have received varicella vaccination, which was similar to those in unvaccinated children (1.1%). However, only one ORF22 sequence was isolated from an unvaccinated 5-year boy. Compared to the reference VZV sequences, the nucleotide homology was estimated to be 99.7% with genotype J. Conclusions Our study indicated that about half of Chinese children aged four to six years have a high risk of VZV infection. It should be helpful for the evaluation on the necessity of varicella immunization in China.
Published: 2019

22. High step‐up DC–DC converter with three‐winding‐coupled‐inductor and output capacitor in series for clean energy

Author: Liu Xinghua, Yu Yang, Yang Jing, Sun Xuefeng, Gao Peng, Li Fei, Zhu Feng, Xue Qicheng, Yao Yu, Geng Ning, Yue Zengwei, Cui Chuan, Ji Suyun, Sun Yan, Sun Jingcheng, Liu Lin, and Richang Xian
Subjects: business.industry, Computer science, 020209 energy, 020208 electrical & electronic engineering, Electrical engineering, Hardware_PERFORMANCEANDRELIABILITY, 02 engineering and technology, Converters, Inductor, law.invention, Capacitor, Hardware_GENERAL, law, Electromagnetic coil, Hardware_INTEGRATEDCIRCUITS, 0202 electrical engineering, electronic engineering, information engineering, Voltage spike, Electrical and Electronic Engineering, business, Electronic circuit, Voltage, Leakage (electronics)
Abstract: A novel high step-up DC-DC converter with a three-winding-coupled-inductor and an output capacitor in series is proposed in this study. By charging for two windings of dotted terminal connection in series by input source, the proposed converter can achieve a higher gain by using smaller turns ratios when the active switch is turned on. The passive clamping circuits are introduced for not only recycling leakage energy but also alleviating voltage spike on the main switch effectively. Meanwhile, the reverse-recovery problem of the diode is alleviated by the leakage inductor. Thus, the efficiency can be improved. In addition, output capacitors are in series to provide energy so that the volume of the output capacitor is reduced. The operating principle and steady-state analyses of the proposed converter are discussed in detail. Then, the performance of the proposed converter is compared with existing converters. Finally, a prototype circuit is built with a 40-V input voltage, 380-V output voltage, and 400-W output power to verify the performance of the proposed converter.
Published: 2019

23. Progress of tapered semiconductor diode lasers

Author: 龚春阳 Gong Chun-yang, 孙胜明 Sun Sheng-ming, 范杰 Fan Jie, 邹永刚 Zou Yonggang, 杨晶晶 Yang Jing-jing, and 徐莉 Xu Li
Subjects: Semiconductor Diode Lasers, Materials science, business.industry, Optoelectronics, business, Atomic and Molecular Physics, and Optics
Published: 2019

24. A polarization-insensitive broadband terahertz absorber with a multilayer structure

Author: Liu Jiaxuan, Yang Jing, Haifeng Zhang, Zhang Hao, and Hai-Ming Li
Subjects: Power loss, Materials science, Terahertz radiation, business.industry, Physics::Optics, General Physics and Astronomy, 02 engineering and technology, 021001 nanoscience & nanotechnology, Polarization (waves), Tm waves, 01 natural sciences, lcsh:QC1-999, Magnetic field, 010309 optics, Relative bandwidth, 0103 physical sciences, Broadband, Optoelectronics, 0210 nano-technology, Broadband absorption, business, lcsh:Physics
Abstract: In this paper, a polarization-insensitive broadband terahertz absorber (PBTA) is presented and demonstrated, which can realize a polarization-insensitive, and broadband perfect absorption in the terahertz regime. By simulation, the polarization-insensitive broadband absorption is over 90%, which runs from 4.904 THz to 6.632 THz (the relative bandwidth is 29.96%), and the obtained absorption remains a good absorption performance with a wide incident angle for both TE and TM waves. The surface current distributions, power loss densities, electric and magnetic field distributions of such an absorber are investigated to figure out the physical mechanism of such a PBTA. The effects structure parameters on the absorption performance are also studied, which will be a guiding to realize a PBTA. The simulated results show that the proposed multilayer structure can help to design a PBTA. Keywords: Broadband absorber, Terahertz absorber, Fabry-Perot cavity resonance, Multilayer structure
Published: 2018

25. Prediction of Rolling Force for Hot Strip Rolling Based on RFR

Author: Yue Meixia, Ren Yan, Wang Huimin, Yang Jing, Gao Xiaowen, Lv Donghao, and Su Nan
Subjects: Materials science, business.industry, Structural engineering, Hot strip rolling, business
Published: 2021

26. To assess the glucose metabolism using the flash glucose monitoring system (FGMS) in patients with hormone replacement therapy for hypopituitarism

Author: Liu Yunfeng, Li Jie, Hou Xintong, Han Minmin, Yang Dan, Yang Jing, u> Jiaxin, Zhang, He Qiong, Yang Guimei, and Zhang Yi
Subjects: medicine.medical_specialty, Endocrinology, business.industry, Internal medicine, Medicine, In patient, Monitoring system, Hormone replacement therapy, Hypopituitarism, Carbohydrate metabolism, business, medicine.disease
Published: 2021

27. Pure Ion Chromatograms Combined with Advanced Machine Learning Methods Improve Accuracy of Discriminant Models in LC–MS-Based Untargeted Metabolomics

Author: Hongmei Lu, Wentao Zhao, Yi Chen, Zhonglong Lin, Xu Wang, Zhimin Zhang, Miao Tian, and Yang Jing
Subjects: Data Analysis, Male, 0301 basic medicine, Computer science, Pipeline (computing), Pharmaceutical Science, 01 natural sciences, Linear methods, LC–MS, Article, Analytical Chemistry, Machine Learning, 03 medical and health sciences, QD241-441, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Drug Discovery, Humans, Metabolomics, Physical and Theoretical Chemistry, Extreme gradient boosting, Projection (set theory), KPIC2, Principal Component Analysis, Pure Ion Chromatogram, business.industry, 010401 analytical chemistry, Organic Chemistry, Discriminant Analysis, Pattern recognition, UMAP, Middle Aged, Models, Theoretical, 0104 chemical sciences, 030104 developmental biology, Untargeted metabolomics, ROC Curve, Discriminant, Chemistry (miscellaneous), Colonic Neoplasms, Molecular Medicine, Extraction methods, Artificial intelligence, business, Algorithms, Chromatography, Liquid, XGBoost
Abstract: Untargeted metabolomics based on liquid chromatography coupled with mass spectrometry (LC–MS) can detect thousands of features in samples and produce highly complex datasets. The accurate extraction of meaningful features and the building of discriminant models are two crucial steps in the data analysis pipeline of untargeted metabolomics. In this study, pure ion chromatograms were extracted from a liquor dataset and left-sided colon cancer (LCC) dataset by K-means-clustering-based Pure Ion Chromatogram extraction method version 2.0 (KPIC2). Then, the nonlinear low-dimensional embedding by uniform manifold approximation and projection (UMAP) showed the separation of samples from different groups in reduced dimensions. The discriminant models were established by extreme gradient boosting (XGBoost) based on the features extracted by KPIC2. Results showed that features extracted by KPIC2 achieved 100% classification accuracy on the test sets of the liquor dataset and the LCC dataset, which demonstrated the rationality of the XGBoost model based on KPIC2 compared with the results of XCMS (92% and 96% for liquor and LCC datasets respectively). Finally, XGBoost can achieve better performance than the linear method and traditional nonlinear modeling methods on these datasets. UMAP and XGBoost are integrated into KPIC2 package to extend its performance in complex situations, which are not only able to effectively process nonlinear dataset but also can greatly improve the accuracy of data analysis in non-target metabolomics.
Published: 2021
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28. The Biological Function, Mechanism, and Clinical Significance of m6A RNA Modifications in Head and Neck Carcinoma: A Systematic Review

Author: Yu-Jie Ning, You-Ming Zhu, Xiao-Juan Wang, Feng-Yang Jing, and Li-Ming Zhou
Subjects: QH301-705.5, medicine.medical_treatment, Review, medicine.disease_cause, head and neck squamous cell carcinoma, Targeted therapy, Cell and Developmental Biology, medicine, tumor microenvironment, Epigenetics, Biology (General), Tumor microenvironment, epigenetics, Mechanism (biology), business.industry, N6-methyladenosine, Cancer, Cell Biology, medicine.disease, Non-coding RNA, targeted therapy, Head and neck squamous-cell carcinoma, stomatognathic diseases, Cancer research, RNA methylation, business, Carcinogenesis, Developmental Biology
Abstract: Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers, yet the molecular mechanisms underlying its onset and development have not yet been fully elucidated. Indeed, an in-depth understanding of the potential molecular mechanisms underlying HNSCC oncogenesis may aid the development of better treatment strategies. Recent epigenetic studies have revealed that the m6A RNA modification plays important roles in HNSCC. In this review, we summarize the role of m6A modification in various types of HNSCC, including thyroid, nasopharyngeal, hypopharyngeal squamous cell, and oral carcinoma. In addition, we discuss the regulatory roles of m6A in immune cells within the tumor microenvironment, as well as the potential molecular mechanisms. Finally, we review the development of potential targets for treating cancer based on the regulatory functions of m6A, with an aim to improving targeted therapies for HNSCC. Together, this review highlights the important roles that m6A modification plays in RNA synthesis, transport, and translation, and demonstrates that the regulation of m6A-related proteins can indirectly affect mRNA and ncRNA function, thus providing a novel strategy for reengineering intrinsic cell activity and developing simpler interventions to treat HNSCC.
Published: 2021

29. Study on slagging characteristics and prevention of biomass briquette

Author: Yang jing, Yang song, Liu Fang, Sun Xiaoting, Ren Xiaoping, and Tang Xintong
Subjects: lcsh:GE1-350, Briquette, Waste management, business.industry, Combustion process, Environmental science, Biomass, Coal, Furnace temperature, Combustion, business, Layer thickness, lcsh:Environmental sciences
Abstract: It is a high efficiency，energy-saving and emission reduction measure to replace coal with biomass briquette fuel in a layer combustion furnace, but in the combustion process, the serious slagging problem has been restricted the promotion of biomass fuel. By analyzing the combustion characteristics of biomass briquette, the ash fusion characteristics and slagging mechanism, combined with the combustion characteristics of a layer combustion furnace, the important influence of key combustion parameters (furnace temperature, excess air, fuel layer thickness) on the slagging in the furnace is obtained, which provides a scientific basis for taking measures to prevent and control the slagging in the design and operation of the biomass briquette layer combustion furnace.
Published: 2021

30. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Author: Klionsky, Daniel, Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie, Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis, Adeli, Khosrow, Adolph, Timon, Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat, Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed, Agrotis, Alexander, Aguilar, Patricia, Ahmad, S Tariq, Ahmed, Zubair, Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-Abd, Ahmed, Al-Akra, Lina, Al-Gharaibeh, Abeer, Alaoui-Jamali, Moulay, Alberti, Simon, Alcocer-Gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-Bari, M Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo, Altan-Bonnet, Nihal, Altieri, Dario, Álvarez, Élida, Alves, Sara, Alves Da Costa, Cristine, Alzaharna, Mazen, Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal, Ammanathan, Veena, An, Zhenyi, Andersen, Stig, Andrabi, Shaida, Andrade-Silva, Magaiver, Andres, Allen, Angelini, Sabrina, Ann, David, Anozie, Uche, Ansari, Mohammad, Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner, Araya, Jun, Arden, Catherine, Arévalo, Maria-Angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen, Armstrong-James, Darius, Arnauné-Pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela, Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-Fabian, Osnat, Atanasov, Atanas, Au, Alicia, Auberger, Patrick, Auner, Holger, Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-Wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan, Backues, Steven, Bae, Dong-Hun, Bae, Ok-Nam, Bae, Soo Han, Baehrecke, Eric, Baek, Ahruem, Baek, Seung-Hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-Zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima, Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio, Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter, Barmada, Sami, Barreiro, Esther, Barreto, George, Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav, Basagoudanavar, Suresh, Bassham, Diane, Bast, Robert, Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne, Baumgarner, Bradley, Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz, Beck, George, Beers, Michael, Begun, Jakob, Behrends, Christian, Behrens, Georg, Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-Touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-Morales, Raquel, Beltran, Jackeline Soares de Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno, Benito-Cuesta, Irene, Bensalem, Julien, Berchtold, Martin, Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-Torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri, Besteiro, Sebastien, Betin, Virginie, Beyaert, Rudi, Bezbradica, Jelena, Bhaskar, Kiran, Bhatia-Kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor, Bijian, Krikor, Billes, Viktor, Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa, Bjorkoy, Geir, Blanco, Gonzalo, Blas-Garcia, Ana, Blasiak, Janusz, Blomgran, Robert, Blomgren, Klas, Blum, Janice, Boada-Romero, Emilio, Boban, Mirta, Boesze-Battaglia, Kathleen, Boeuf, Philippe, Boland, Barry, Bomont, Pascale, Bonaldo, Paolo, Bonam, Srinivasa Reddy, Bonfili, Laura, Bonifacino, Juan, Boone, Brian, Bootman, Martin, Bordi, Matteo, Borner, Christoph, Bornhauser, Beat, Borthakur, Gautam, Bosch, Jürgen, Bose, Santanu, botana, luis, Botas, Juan, Boulanger, Chantal, Boulton, Michael, Bourdenx, Mathieu, Bourgeois, Benjamin, Bourke, Nollaig, Bousquet, Guilhem, Boya, Patricia, Bozhkov, Peter, Bozi, Luiz, Bozkurt, Tolga, Brackney, Doug, Brandts, Christian, Braun, Ralf, Braus, Gerhard, Bravo-Sagua, Roberto, Bravo-San Pedro, José, Brest, Patrick, Bringer, Marie-Agnès, Briones-Herrera, Alfredo, Broaddus, V Courtney, Brodersen, Peter, Brodsky, Jeffrey, Brody, Steven, Bronson, Paola, Bronstein, Jeff, Brown, Carolyn, Brown, Rhoderick, Brum, Patricia, Brumell, John, Brunetti-Pierri, Nicola, Bruno, Daniele, Bryson-Richardson, Robert, Bucci, Cecilia, Buchrieser, Carmen, Bueno, Marta, Buitrago-Molina, Laura Elisa, Buraschi, Simone, Buch, Shilpa, Buchan, J Ross, Buckingham, Erin, Budak, Hikmet, Budini, Mauricio, Bultynck, Geert, Burada, Florin, Burgoyne, Joseph, Burón, M Isabel, Bustos, Victor, Büttner, Sabrina, Butturini, Elena, Byrd, Aaron, Cabas, Isabel, Cabrera-Benitez, Sandra, Cadwell, Ken, Cai, Jingjing, Cai, Lu, Cai, Qian, Cairó, Montserrat, Calbet, Jose, Caldwell, Guy, Caldwell, Kim, Call, Jarrod, Calvani, Riccardo, Calvo, Ana, Calvo-Rubio Barrera, Miguel, Camara, Niels OS, Camonis, Jacques, Camougrand, Nadine, Campanella, Michelangelo, Campbell, Edward, Campbell-Valois, François-Xavier, Campello, Silvia, Campesi, Ilaria, Campos, Juliane, Camuzard, Olivier, Cancino, Jorge, Candido de Almeida, Danilo, Canesi, Laura, Caniggia, Isabella, Canonico, Barbara, Cantí, Carles, Cao, Bin, Caraglia, Michele, Caramés, Beatriz, Carchman, Evie, Cardenal-Muñoz, Elena, Cardenas, Cesar, Cardenas, Luis, Cardoso, Sandra, Carew, Jennifer, Carle, Georges, Carleton, Gillian, Carloni, Silvia, Carmona-Gutierrez, Didac, Carneiro, Leticia, Carnevali, Oliana, Carosi, Julian, Carra, Serena, Carrier, Alice, Carrier, Lucie, Carroll, Bernadette, Carter, A Brent, Carvalho, Andreia Neves, Casanova, Magali, Casas, Caty, Casas, Josefina, Cassioli, Chiara, Castillo, Eliseo, Castillo, Karen, Castillo-Lluva, Sonia, Castoldi, Francesca, Castori, Marco, Castro, Ariel, Castro-Caldas, Margarida, Castro-Hernandez, Javier, Castro-Obregon, Susana, Catz, Sergio, Cavadas, Claudia, Cavaliere, Federica, Cavallini, Gabriella, Cavinato, Maria, Cayuela, Maria, Cebollada Rica, Paula, Cecarini, Valentina, Cecconi, Francesco, Cechowska-Pasko, Marzanna, Cenci, Simone, Ceperuelo-Mallafré, Victòria, Cerqueira, João, Cerutti, Janete, Cervia, Davide, Cetintas, Vildan Bozok, Cetrullo, Silvia, Chae, Han-Jung, Chagin, Andrei, Chai, Chee-Yin, Chakrabarti, Gopal, Chakrabarti, Oishee, Chakraborty, Tapas, Chakraborty, Trinad, Chami, mounia, Chamilos, Georgios, Chan, David, Chan, Edmond, Chan, Edward, Chan, H.Y. Edwin, Chan, Helen, Chan, Hung, Chan, Matthew, Chan, Yau Sang, Chandra, Partha, Chang, Chih-Peng, Chang, Chunmei, Chang, Hao-Chun, Chang, Kai, Chao, Jie, Chapman, Tracey, Charlet-Berguerand, Nicolas, Chatterjee, Samrat, Chaube, Shail, Chaudhary, Anu, Chauhan, Santosh, Chaum, Edward, Checler, Frédéric, Cheetham, Michael, Chen, Chang-Shi, Chen, Guang-Chao, Chen, Jian-Fu, Chen, Liam, Chen, Leilei, Chen, Lin, Chen, Mingliang, Chen, Mu-Kuan, Chen, Ning, Chen, Quan, Chen, Ruey-Hwa, Chen, Shi, Chen, Wei, Chen, Weiqiang, Chen, Xin-Ming, Chen, Xiong-Wen, Chen, Xu, Chen, Yan, Chen, Ye-Guang, Chen, Yingyu, Chen, Yongqiang, Chen, Yu-Jen, Chen, Yue-Qin, Chen, Zhefan Stephen, Chen, Zhi, Chen, Zhi-Hua, Chen, Zhijian, Chen, Zhixiang, Cheng, Hanhua, Cheng, Jun, Cheng, Shi-Yuan, Cheng, Wei, Cheng, Xiaodong, Cheng, Xiu-Tang, Cheng, Yiyun, Cheng, Zhiyong, Chen, Zhong, Cheong, Heesun, Cheong, Jit Kong, Chernyak, Boris, Cherry, Sara, Cheung, Chi Fai Randy, Cheung, Chun Hei Antonio, Cheung, King-Ho, Chevet, Eric, Chi, Richard, Chiang, Alan Kwok Shing, Chiaradonna, Ferdinando, Chiarelli, Roberto, Chiariello, Mario, Chica, Nathalia, Chiocca, Susanna, Chiong, Mario, Chiou, Shih-Hwa, Chiramel, Abhilash, Chiurchiù, Valerio, Cho, Dong-Hyung, Choe, Seong-Kyu, Choi, Augustine, Choi, Mary, Choudhury, Kamalika Roy, Chow, Norman, Chu, Charleen, Chua, Jason, Chua, John Jia En, Chung, Hyewon, Chung, Kin Pan, Chung, Seockhoon, Chung, So-Hyang, Chung, Yuen-Li, Cianfanelli, Valentina, Ciechomska, Iwona, Cifuentes, Mariana, Cinque, Laura, Cirak, Sebahattin, Cirone, Mara, Clague, Michael, Clarke, Robert, Clementi, Emilio, Coccia, Eliana, Codogno, Patrice, Cohen, Ehud, Cohen, Mickael, Colasanti, Tania, Colasuonno, Fiorella, Colbert, Robert, Colell, Anna, Čolić, Miodrag, Coll, Nuria, Collins, Mark, Colombo, María, Colón-Ramos, Daniel, Combaret, Lydie, Comincini, Sergio, Cominetti, Márcia, Consiglio, Antonella, Conte, Andrea, Conti, Fabrizio, Contu, Viorica Raluca, Cookson, Mark, Coombs, Kevin, Coppens, Isabelle, Corasaniti, Maria Tiziana, Corkery, Dale, Cordes, Nils, Cortese, Katia, Costa, Maria do Carmo, Costantino, Sarah, Costelli, Paola, Coto-Montes, Ana, Crack, Peter, Crespo, Jose, Criollo, Alfredo, Crippa, Valeria, Cristofani, Riccardo, Csizmadia, Tamas, Cuadrado, Antonio, Cui, Bing, Cui, Jun, Cui, Yixian, Cui, Yong, Culetto, Emmanuel, Cumino, Andrea, Cybulsky, Andrey, Czaja, Mark, Czuczwar, Stanislaw, D'Adamo, Stefania, D'Amelio, Marcello, D'Arcangelo, Daniela, D'Lugos, Andrew, D'Orazi, Gabriella, da Silva, James, Dafsari, Hormos Salimi, Dagda, Ruben, Dagdas, Yasin, Daglia, Maria, Dai, Xiaoxia, Dai, Yun, Dai, Yuyuan, Dal Col, Jessica, Dalhaimer, Paul, Dalla Valle, Luisa, Dallenga, Tobias, Dalmasso, Guillaume, Damme, Markus, Dando, Ilaria, Dantuma, Nico, Darling, April, Das, Hiranmoy, Dasarathy, Srinivasan, Dasari, Santosh, Dash, Srikanta, Daumke, Oliver, Dauphinee, Adrian, Davies, Jeffrey, Dávila, Valeria, Davis, Roger, Davis, Tanja, Dayalan Naidu, Sharadha, De Amicis, Francesca, De Bosscher, Karolien, De Felice, Francesca, De Franceschi, Lucia, De Leonibus, Chiara, de Mattos Barbosa, Mayara, De Meyer, Guido, De Milito, Angelo, De Nunzio, Cosimo, De Palma, Clara, De Santi, Mauro, De Virgilio, Claudio, De Zio, Daniela, Debnath, Jayanta, DeBosch, Brian, Decuypere, Jean-Paul, Deehan, Mark, Deflorian, Gianluca, DeGregori, James, Dehay, Benjamin, Del Rio, Gabriel, Delaney, Joe, Delbridge, Lea, Delorme-Axford, Elizabeth, Delpino, M Victoria, Demarchi, Francesca, Dembitz, Vilma, Demers, Nicholas, Deng, Hongbin, Deng, Zhiqiang, Dengjel, Joern, Dent, Paul, Denton, Donna, DePamphilis, Melvin, Der, Channing, Deretic, Vojo, Descoteaux, Albert, Devis, Laura, Devkota, Sushil, Devuyst, Olivier, Dewson, Grant, Dharmasivam, Mahendiran, Dhiman, Rohan, di Bernardo, Diego, Di Cristina, Manlio, Di Domenico, Fabio, Di Fazio, Pietro, Di Fonzo, Alessio, Di Guardo, Giovanni, Di Guglielmo, Gianni, Di Leo, Luca, Di Malta, Chiara, Di Nardo, Alessia, Di Rienzo, Martina, Di Sano, 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Eissa, N Tony, Eissa, Sanaa, Ejarque, Miriam, El Andaloussi, Abdeljabar, El-Hage, Nazira, El-Naggar, Shahenda, Eleuteri, Anna Maria, El-Shafey, Eman, Elgendy, Mohamed, Eliopoulos, Aristides, Elizalde, María, Elks, Philip, Elsasser, Hans-Peter, Elsherbiny, Eslam, Emerling, Brooke, Emre, N., Eng, Christina, Engedal, Nikolai, Engelbrecht, Anna-Mart, Engelsen, Agnete, Enserink, Jorrit, Escalante, Ricardo, Esclatine, Audrey, Escobar-Henriques, Mafalda, Eskelinen, Eeva-Liisa, Espert, Lucile, Eusebio, Makandjou-Ola, Fabrias, Gemma, Fabrizi, Cinzia, Facchiano, Antonio, Facchiano, Francesco, Fadeel, Bengt, Fader, Claudio, Faesen, Alex, Fairlie, W Douglas, Falcó, Alberto, Falkenburger, Bjorn, Fan, Daping, Fan, Jie, Fan, Yanbo, Fang, Evandro, Fang, Yanshan, Fang, Yognqi, Fanto, Manolis, Farfel-Becker, Tamar, Faure, Mathias, Fazeli, Gholamreza, Fedele, Anthony, Feldman, Arthur, Feng, Du, Feng, Jiachun, Feng, Lifeng, Feng, Yibin, Feng, Yuchen, Feng, Wei, Fenz Araujo, Thais, Ferguson, Thomas, Fernández, Álvaro, Fernandez-Checa, Jose, Fernández-Veledo, Sonia, Fernie, Alisdair, Ferrante, Anthony, Ferraresi, Alessandra, Ferrari, Merari, Ferreira, Julio, Ferro-Novick, Susan, Figueras, Antonio, Filadi, Riccardo, Filigheddu, Nicoletta, Filippi-Chiela, Eduardo, Filomeni, Giuseppe, Fimia, Gian Maria, Fineschi, Vittorio, Finetti, Francesca, Finkbeiner, Steven, Fisher, Edward, Fisher, Paul, Flamigni, Flavio, Fliesler, Steven, Flo, Trude, Florance, Ida, Florey, Oliver, Florio, Tullio, Fodor, Erika, Follo, Carlo, Fon, Edward, Forlino, Antonella, Fornai, Francesco, Fortini, Paola, Fracassi, Anna, Fraldi, Alessandro, Franco, Brunella, Franco, Rodrigo, Franconi, Flavia, Frankel, Lisa, Friedman, Scott, Fröhlich, Leopold, Frühbeck, Gema, Fuentes, Jose, Fujiki, Yukio, Fujita, Naonobu, Fujiwara, Yuuki, Fukuda, Mitsunori, Fulda, Simone, Furic, Luc, Furuya, Norihiko, Fusco, Carmela, Gack, Michaela, Gaffke, Lidia, Galadari, Sehamuddin, Galasso, Alessia, Galindo, Maria, Gallolu Kankanamalage, Sachith, Galluzzi, Lorenzo, Galy, Vincent, Gammoh, Noor, Gan, Boyi, Ganley, Ian, Gao, Feng, Gao, Hui, Gao, Minghui, Gao, Ping, Gao, Shou-Jiang, Gao, Wentao, Gao, Xiaobo, Garcera, Ana, Garcia, Maria Noé, Garcia, Verónica, García-del Portillo, Francisco, Garcia-Escudero, Vega, Garcia-Garcia, Aracely, Garcia-Macia, Marina, García-Moreno, Diana, Garcia-Ruiz, Carmen, García-Sanz, Patricia, Garg, Abhishek, Gargini, Ricardo, Garofalo, Tina, Garry, Robert, Gassen, Nils, Gatica, Damian, Ge, Liang, Ge, Wanzhong, Geiss-Friedlander, Ruth, Gelfi, Cecilia, Genschik, Pascal, Gentle, Ian, Gerbino, Valeria, Gerhardt, Christoph, Germain, Kyla, Germain, Marc, Gewirtz, David, Ghasemipour Afshar, Elham, Ghavami, Saeid, Ghigo, Alessandra, Ghosh, Manosij, Giamas, Georgios, Giampietri, Claudia, Giatromanolaki, Alexandra, Gibson, Gary, Gibson, Spencer, Ginet, Vanessa, Giniger, Edward, Giorgi, Carlotta, Girao, Henrique, Girardin, Stephen, Giridharan, Mridhula, Giuliano, Sandy, Giulivi, Cecilia, Giuriato, Sylvie, Giustiniani, Julien, Gluschko, Alexander, Goder, Veit, Goginashvili, Alexander, Golab, Jakub, Goldstone, David, Golebiewska, Anna, Gomes, Luciana, Gomez, Rodrigo, Gómez-Sánchez, Rubén, Gomez-Puerto, Maria Catalina, Gomez-Sintes, Raquel, Gong, Qingqiu, Goni, Felix, González-Gallego, Javier, Gonzalez-Hernandez, Tomas, Gonzalez-Polo, Rosa, Gonzalez-Reyes, Jose, González-Rodríguez, Patricia, Goping, Ing Swie, Gorbatyuk, Marina, Gorbunov, Nikolai, Görgülü, Kıvanç, Gorojod, Roxana, Gorski, Sharon, Goruppi, Sandro, Gotor, Cecilia, Gottlieb, Roberta, Gozes, Illana, Gozuacik, Devrim, Graef, Martin, Gräler, Markus, Granatiero, Veronica, Grasso, Daniel, Gray, Joshua, Green, Douglas, Greenhough, Alexander, Gregory, Stephen, Griffin, Edward, Grinstaff, Mark, Gros, Frederic, Grose, Charles, Gross, Angelina, Gruber, Florian, Grumati, Paolo, Grune, Tilman, Gu, Xueyan, Guan, Jun-Lin, Guardia, Carlos, Guda, Kishore, Guerra, Flora, Guerri, Consuelo, Guha, Prasun, Guillén, Carlos, Gujar, Shashi, 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Elena, Uchiyama, Yasuo, Ugun-Klusek, Aslihan, Uhlig, Holm, Ułamek-Kozioł, Marzena, Ulasov, Ilya, Umekawa, Midori, Ungermann, Christian, Unno, Rei, Urbe, Sylvie, Uribe-Carretero, Elisabet, Üstün, Suayib, Uversky, Vladimir, Vaccari, Thomas, Vaccaro, Maria, Vahsen, Björn, Vakifahmetoglu-Norberg, Helin, Valdor, Rut, Valente, Maria, Valko, Ayelén, Vallee, Richard, Valverde, Angela, Van Den Berghe, Greet, van der Veen, Stijn, Van Kaer, Luc, van Loosdregt, Jorg, van Wijk, Sjoerd, Vandenberghe, Wim, Vanhorebeek, Ilse, Vannier-Santos, Marcos, Vannini, Nicola, Vanrell, M Cristina, Vantaggiato, Chiara, Varano, Gabriele, Varela-Nieto, Isabel, Varga, Máté, Vasconcelos, M Helena, Vats, Somya, Vavvas, Demetrios, Vega-Naredo, Ignacio, Vega-Rubin-de-Celis, Silvia, Velasco, Guillermo, Velázquez, Ariadna, Vellai, Tibor, Vellenga, Edo, Velotti, Francesca, Verdier, Mireille, Verginis, Panayotis, Vergne, Isabelle, Verkade, Paul, Verma, Manish, Verstreken, Patrik, Vervliet, Tim, Vervoorts, Jörg, Vessoni, Alexandre, Victor, Victor, Vidal, Michel, Vidoni, Chiara, Vieira, Otilia, Vierstra, Richard, Viganó, Sonia, Vihinen, Helena, Vijayan, Vinoy, Vila, Miquel, Vilar, Marçal, Villalba, José, Villalobo, Antonio, Villarejo-Zori, Beatriz, Villarroya, Francesc, Villarroya, Joan, Vincent, Olivier, Vindis, Cecile, Viret, Christophe, Viscomi, Maria Teresa, Visnjic, Dora, Vitale, Ilio, Vocadlo, David, Voitsekhovskaja, Olga, Volonté, Cinzia, Volta, Mattia, Vomero, Marta, Von Haefen, Clarissa, Vooijs, Marc, Voos, Wolfgang, Vucicevic, Ljubica, Wade-Martins, Richard, Waguri, Satoshi, Waite, Kenrick, Wakatsuki, Shuji, Walker, David, Walker, Mark, Walker, Simon, Walter, Jochen, Wandosell, Francisco, Wang, Bo, Wang, Chao-Yung, Wang, Chen, Wang, Chenran, Wang, Chenwei, Wang, Cun-Yu, Wang, Dong, Wang, Fangyang, Wang, Feng, Wang, Fengming, Wang, Guansong, Wang, Han, Wang, Hao, Wang, Hexiang, Wang, Hong-Gang, Wang, Jianrong, Wang, Jigang, Wang, Jiou, Wang, Jundong, Wang, Kui, Wang, Lianrong, Wang, Liming, Wang, Maggie Haitian, Wang, Meiqing, Wang, Nanbu, Wang, PengWei, Wang, PeiPei, Wang, Ping, Wang, Qing Jun, Wang, Qing, Wang, Qing Kenneth, Wang, Qiong, Wang, Wen-Tao, Wang, Wuyang, Wang, Xinnan, Wang, Xuejun, Wang, Yan, Wang, Yanchang, Wang, Yanzhuang, Wang, Yen-Yun, Wang, Yihua, Wang, Yipeng, Wang, Yu, wang, yuqi, Wang, Zhe, Wang, Zhenyu, Wang, Zhouguang, Warnes, Gary, Warnsmann, Verena, Watada, Hirotaka, Watanabe, Eizo, Watchon, Maxinne, Wawrzyńska, Anna, Weaver, Timothy, Wegrzyn, Grzegorz, Wehman, Ann, Wei, Huafeng, Wei, Lei, Wei, Taotao, Wei, Yongjie, Weiergräber, Oliver, Weihl, Conrad, Weindl, Günther, Weiskirchen, Ralf, Wells, Alan, Wen, Runxia, Wen, Xin, Werner, Antonia, Weykopf, Beatrice, Wheatley, Sally, Whitton, J Lindsay, Whitworth, Alexander, Wiktorska, Katarzyna, Wildenberg, Manon, Wileman, Tom, Wilkinson, Simon, Willbold, Dieter, Williams, Brett, Williams, Robin, Williams, Roger, Williamson, Peter, Wilson, Richard, Winner, Beate, Winsor, Nathaniel, Witkin, Steven, Wodrich, Harald, Woehlbier, Ute, Wollert, Thomas, Wong, Esther, Wong, Jack Ho, Wong, Richard, Wong, Vincent Kam Wai, Wong, W Wei-Lynn, Wu, An-Guo, Wu, Chengbiao, Wu, Jian, Wu, Junfang, Wu, Kenneth, Wu, Min, Wu, Shan-Ying, Wu, Shengzhou, Wu, Shu-Yan, Wu, Shufang, Wu, William, Wu, Xiaohong, Wu, Xiaoqing, Wu, Yao-Wen, Wu, Yihua, Xavier, Ramnik, Xia, Hongguang, Xia, Lixin, Xia, Zhengyuan, Xiang, Ge, Xiang, Jin, Xiang, Mingliang, Xiang, Wei, Xiao, Bin, Xiao, Guozhi, Xiao, Hengyi, Xiao, Hong-tao, Xiao, Jian, Xiao, Lan, Xiao, Shi, Xiao, Yin, Xie, Baoming, Xie, Chuan-Ming, Xie, Min, Xie, Yuxiang, Xie, Zhiping, Xie, Zhonglin, Xilouri, Maria, Xu, Congfeng, Xu, En, Xu, Haoxing, Xu, Jing, Xu, Jinrong, Xu, Liang, Xu, Wen Wen, Xu, Xiulong, Xue, Yu, Yakhine-Diop, Sokhna, Yamaguchi, Masamitsu, Yamaguchi, Osamu, Yamamoto, Ai, Yamashina, Shunhei, Yan, Shengmin, Yan, Shian-Jang, Yan, Zhen, Yanagi, Yasuo, Yang, Chuanbin, Yang, Dun-Sheng, Yang, Huan, Yang, Huang-Tian, Yang, Hui, Yang, Jin-Ming, Yang, Jing, Yang, Jingyu, Yang, Ling, Yang, Liu, Yang, Ming, Yang, Pei-Ming, Yang, Qian, Yang, Seungwon, Yang, Shu, Yang, Shun-Fa, Yang, Wannian, Yang, Wei Yuan, Yang, Xiaoyong, Yang, Xuesong, Yang, Yi, Yang, Ying, Yao, Honghong, Yao, Shenggen, Yao, Xiaoqiang, Yao, Yong-Gang, Yao, Yong-Ming, Yasui, Takahiro, Yazdankhah, Meysam, Yen, Paul, Yi, Cong, Yin, Xiao-Ming, Yin, Yanhai, Yin, Zhangyuan, Yin, Ziyi, Ying, Meidan, Ying, Zheng, Yip, Calvin, Yiu, Stephanie Pei Tung, Yoo, Young, Yoshida, Kiyotsugu, Yoshii, Saori, Yoshimori, Tamotsu, Yousefi, Bahman, Yu, Boxuan, Yu, Haiyang, Yu, Jun, Yu, Li, Yu, Ming-Lung, Yu, Seong-Woon, Yu, Victor, Yu, W Haung, Yu, Zhengping, Yu, Zhou, Yuan, Junying, Yuan, Ling-Qing, Yuan, Shilin, Yuan, Shyng-Shiou, Yuan, Yanggang, Yuan, Zengqiang, Yue, Jianbo, Yue, Zhenyu, Yun, Jeanho, Yung, Raymond, Zacks, David, Zaffagnini, Gabriele, Zambelli, Vanessa, Zanella, Isabella, Zang, Qun, Zanivan, Sara, Zappavigna, Silvia, Zaragoza, Pilar, Zarbalis, Konstantinos, Zarebkohan, Amir, Zarrouk, Amira, Zeitlin, Scott, Zeng, Jialiu, Zeng, Ju-deng, Žerovnik, Eva, Zhan, Lixuan, Zhang, Bin, Zhang, Donna, Zhang, Hanlin, Zhang, Hong, Zhang, Honghe, Zhang, Huafeng, Zhang, Huaye, Zhang, Hui, Zhang, Hui-Ling, Zhang, Jianbin, Zhang, Jianhua, Zhang, Jing-Pu, Zhang, Kalin, Zhang, Leshuai, Zhang, Lin, Zhang, Lisheng, Zhang, Lu, Zhang, Luoying, Zhang, Menghuan, Zhang, Peng, Zhang, Sheng, Zhang, Wei, Zhang, Xiangnan, Zhang, Xiao-Wei, Zhang, Xiaolei, Zhang, Xiaoyan, Zhang, Xin, Zhang, Xinxin, Zhang, Xu Dong, Zhang, Yang, Zhang, Yanjin, Zhang, Yi, Zhang, Ying-Dong, Zhang, Yingmei, Zhang, Yuan-Yuan, Zhang, Yuchen, Zhang, Zhe, Zhang, Zhengguang, Zhang, Zhibing, Zhang, Zhihai, Zhang, Zhiyong, Zhang, Zili, Zhao, Haobin, Zhao, Lei, Zhao, Shuang, Zhao, Tongbiao, Zhao, Xiao-Fan, Zhao, Ying, Zhao, Yongchao, Zhao, Yongliang, Zhao, Yuting, Zheng, Guoping, Zheng, Kai, Zheng, Ling, Zheng, Shizhong, Zheng, Xi-Long, Zheng, Yi, Zheng, Zu-Guo, Zhivotovsky, Boris, Zhong, Qing, Zhou, Ao, Zhou, Ben, Zhou, Cefan, ZHOU, Gang, Zhou, Hao, Zhou, Hong, Zhou, Hongbo, Zhou, Jie, Zhou, Jing, Zhou, Jiyong, Zhou, Kailiang, Zhou, Rongjia, Zhou, Xu-jie, Zhou, Yanshuang, Zhou, Yinghong, Zhou, Yubin, Zhou, Zheng-Yu, Zhou, Zhou, Zhu, Binglin, Zhu, Changlian, Zhu, Guo-Qing, Zhu, Haining, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-Guo, Zhu, Yanping, Zhu, Yushan, Zhuang, Haixia, Zhuang, Xiaohong, Zientara-Rytter, Katarzyna, Zimmermann, Christine, Ziviani, Elena, Zoladek, Teresa, Zong, Wei-Xing, Zorov, Dmitry, Zorzano, Antonio, Zou, Weiping, Zou, Zhen, Zou, Zhengzhi, Zuryn, Steven, Zwerschke, Werner, Brand-Saberi, Beate, Dong, X Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith, Stallings, Christina, Tong, Chun-Kit, Ahmad, S. Tariq, Alim Al-Bari, M. Abdul, Bechara, Luiz R.G., Behrens, Georg M.N., Bhuiyan, Md. Shenuarin, Broaddus, V. Courtney, Buchan, J. Ross, Burón, M. Isabel, Carter, A. Brent, Chan, Matthew T.V., Choi, Augustine M.K., D’Adamo, Stefania, D’Amelio, Marcello, D’Arcangelo, Daniela, D’Lugos, Andrew, D’Orazi, Gabriella, De Meyer, Guido R.Y., Delpino, M. Victoria, Distler, Jörg H.W., Dixon, Ian M.C., Dobson, Renwick C.J., 2nd Dorn, Gerald, Eissa, N. Tony, Engelsen, Agnete S.T., Fairlie, W. Douglas, Ferreira, Julio C.B., H.B., Ranjitha, Hanson, Phyllis I., Hejtmancik, J. Fielding, Ho, Idy H.T., Hobbs, G. Aaron, Hoet, Peter H.M., Huang, Michael L.H., Iyer, Anand Krishnan V., Johnson, Gail V.W., Joosten, Leo A.B., Karim, Md. Razaul, Kaufmann, Stefan H.E., Ko, Ben C.B., Leck, Lionel Y.W., Lima, Thania R.R., Livingston, J. Andrew, Martin, Alexandre P.J., Montes, L. Ruth, Murphy, J. Patrick, Ng, Charlene C.W., Nicolao, M. Celeste, O’Donovan, Tracey, O’Leary, Seónadh, O’Rourke, Eyleen, O’Sullivan, Mary, O’Sullivan, Timothy, Omary, M. Bishr, Pereira, Gustavo J.S., Ratnayaka, J. Arjuna, Riazuddin, S. Amer, Rouschop, Kasper M.A., Sanderson, J. Thomas, Scaglione, K. Matthew, Schapira, Anthony H.V., Scovassi, A. Ivana, St. Clair, Daret, Sunahara, Karen K.S., Symons, J. David, Triola, Gemma, van Wijk, Sjoerd J.L., Vanrell, M. Cristina, Vasconcelos, M. Helena, Whitton, J. Lindsay, Williams, Robin S.B., Wong, W. Wei-Lynn, Wu, William K.K., Yakhine-Diop, Sokhna M.S., Yu, W. Haung, Zhang, Kalin Y.B., Dong, X. Charlie, Ain Shams University [ASU], Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University [JGU], Medical University Graz, Centre de Recherche des Cordeliers [CRC (UMR_S_1138 / U1138)], Institut Pasteur d'Iran, Leibniz Institute of Plant Biochemistry [IPB], The University of Texas M.D. Anderson Cancer Center [Houston], Institut de pharmacologie moléculaire et cellulaire [IPMC], Lipides - Nutrition - Cancer [Dijon - U1231] [LNC], Centre méditerranéen de médecine moléculaire [C3M], Institut de Biologie Valrose [IBV], Petites Molécules de neuroprotection, neurorégénération et remyélinisation, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Institut Cochin [IC UM3 (UMR 8104 / U1016)], Institut NeuroMyoGène [INMG], Paris-Centre de Recherche Cardiovasculaire [PARCC (UMR_S 970/ U970)], Marqueurs cardiovasculaires en situation de stress [MASCOT (UMR_S_942 / U942)], Institut de Recherche sur le Cancer et le Vieillissement [IRCAN], Centre de Recherche en Cancérologie de Marseille [CRCM], Centre for Integrative Biology - CBI [Inserm U964 - CNRS UMR7104 - IGBMC], Oncogenesis, Stress, Signaling [OSS], Institut Necker Enfants-Malades [INEM - UM 111 (UMR 8253 / U1151)], Institut de Biologie Intégrative de la Cellule [I2BC], Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte [M2iSH], Centre de Recherches en Cancérologie de Toulouse [CRCT], Physiopathologie et traitement des maladies du foie, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL], Institut de Génétique et de Biologie Moléculaire et Cellulaire [IGBMC], Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] [BIO-PEROXIL], Centre de recherche sur l'Inflammation [CRI (UMR_S_1149 / ERL_8252 / U1149)], Unité de génétique et biologie des cancers [U830], Laboratoire d'Optique et Biosciences [LOB], Institut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC], Différenciation et communication neuronale et neuroendocrine [DC2N], Institut de Recherche en Cancérologie de Montpellier [IRCM - U1194 Inserm - UM], Centre d'Immunologie de Marseille - Luminy [CIML], Physiopathologie et imagerie des troubles neurologiques [PhIND], Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée [LBFA], Imagine - Institut des maladies génétiques (IHU) [Imagine - U1163], Institut Mondor de Recherche Biomédicale [IMRB], Franco-czech Laboratory for clinical research on obesity, University of Michigan [Ann Arbor], University of Michigan System, Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut de Biologie Valrose (IBV), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP), Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Nutrition, Métabolisme, Aquaculture (NuMéA), Université de Pau et des Pays de l'Adour (UPPA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut NeuroMyoGène (INMG), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Centre for Integrative Biology - CBI (Inserm U964 - CNRS UMR7104 - IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institute of genetics and molecular and cellular biology-Centre National de la Recherche Scientifique (CNRS), Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Unité de Nutrition Humaine (UNH), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut des Maladies Neurodégénératives [Bordeaux] (IMN), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physiologie et Génomique des Poissons (LPGP), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] (BIO-PEROXIL), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut Jean-Pierre Bourgin (IJPB), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de génétique et biologie des cancers (U830), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'Optique et Biosciences (LOB), École polytechnique (X)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Différenciation et communication neuronale et neuroendocrine (DC2N), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie et imagerie des troubles neurologiques (PhIND), Université de Caen Normandie (UNICAEN), Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée (LBFA), Université Grenoble Alpes (UGA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Epithelial biology and disease - Liliane Bettencourt Chair of Developmental Biology (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Biomécanique cellulaire et respiratoire (BCR), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Charles University [Prague]-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by the National Institute of General Medical Sciences [GM131919]., Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Université Sorbonne Paris Nord, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Département Plateforme (PF I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Gustave Roussy (IGR), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Chinese Academy of Medical Sciences [Suzhou, Chine] (CAMS), Karolinska Institutet [Stockholm], Karolinska University Hospital [Stockholm], Department of Women's and Children's Health [Stockholm, Sweden], Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École polytechnique (X), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, FHU OncoAge - Pathologies liées à l’âge [CHU Nice] (OncoAge), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Institut de Pharmacologie Moléculaire et Cellulaire [UNIV Côte d'Azur] (UPMC), Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Life Sciences Institute [Ann Arbor, MI, USA], University of Michigan System-University of Michigan System, European Institute of Oncology IRCCS [Milan, Italy] (EIO), Ain Shams University (ASU), Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Réseau International des Instituts Pasteur (RIIP), Leibniz Institute of Plant Biochemistry (IPB), Hebrew University of Jerusalem, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Oncogenesis, Stress, Signaling (OSS), Institut des Maladies Métaboliques et Casdiovasculaires (UPS/Inserm U1297 - I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Charles University [Prague] (CU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Klionsky, D. 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P., Whitton, J. L., Whitworth, A. J., Wiktorska, K., Wildenberg, M. E., Wileman, T., Wilkinson, S., Willbold, D., Williams, B., Williams, R. S. B., Williams, R. L., Williamson, P. R., Wilson, R. A., Winner, B., Winsor, N. J., Witkin, S. S., Wodrich, H., Woehlbier, U., Wollert, T., Wong, E., Wong, J. H., Wong, R. W., Wong, V. K. W., Wong, W. W. -L., Wu, A. -G., Wu, C., Wu, J., Wu, K. K., Wu, M., Wu, S. -Y., Wu, S., Wu, W. K. K., Wu, X., Wu, Y. -W., Wu, Y., Xavier, R. J., Xia, H., Xia, L., Xia, Z., Xiang, G., Xiang, J., Xiang, M., Xiang, W., Xiao, B., Xiao, G., Xiao, H., Xiao, H. -T., Xiao, J., Xiao, L., Xiao, S., Xiao, Y., Xie, B., Xie, C. -M., Xie, M., Xie, Y., Xie, Z., Xilouri, M., Xu, C., Xu, E., Xu, H., Xu, J., Xu, L., Xu, W. W., Xu, X., Xue, Y., Yakhine-Diop, S. M. 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D., Zhang, H., Zhang, H. -L., Zhang, J., Zhang, J. -P., Zhang, K. Y. B., Zhang, L. W., Zhang, L., Zhang, M., Zhang, P., Zhang, S., Zhang, W., Zhang, X., Zhang, X. -W., Zhang, X. D., Zhang, Y., Zhang, Y. -D., Zhang, Y. -Y., Zhang, Z., Zhao, H., Zhao, L., Zhao, S., Zhao, T., Zhao, X. -F., Zhao, Y., Zheng, G., Zheng, K., Zheng, L., Zheng, S., Zheng, X. -L., Zheng, Y., Zheng, Z. -G., Zhivotovsky, B., Zhong, Q., Zhou, A., Zhou, B., Zhou, C., Zhou, G., Zhou, H., Zhou, J., Zhou, K., Zhou, R., Zhou, X. -J., Zhou, Y., Zhou, Z. -Y., Zhou, Z., Zhu, B., Zhu, C., Zhu, G. -Q., Zhu, H., Zhu, W. -G., Zhu, Y., Zhuang, H., Zhuang, X., Zientara-Rytter, K., Zimmermann, C. M., Ziviani, E., Zoladek, T., Zong, W. -X., Zorov, D. B., Zorzano, A., Zou, W., Zou, Z., Zuryn, S., Zwerschke, W., Brand-Saberi, B., Dong, X. C., Kenchappa, C. S., Lin, Y., Oshima, S., Rong, Y., Sluimer, J. C., Stallings, C. L., Tong, C. -K., and Centre National de la Recherche Scientifique (CNRS)
Subjects: 0301 basic medicine, Programmed cell death, Settore BIO/06, Autophagosome, Autolysosome, [SDV]Life Sciences [q-bio], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Autophagy-Related Proteins, Review, Computational biology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Settore MED/04, 03 medical and health sciences, stress, Chaperone-mediated autophagy, ddc:570, Autophagy, LC3, Animals, Humans, cancer, Settore BIO/10, flux, lysosome, macroautophagy, neurodegeneration, phagophore, vacuole, Set (psychology), Molecular Biology, 030102 biochemistry & molecular biology, business.industry, Interpretation (philosophy), Autophagosomes, Cell Biology, Multicellular organism, 030104 developmental biology, Knowledge base, Biological Assay, Lysosomes, business, Biomarkers, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: Contains fulltext : 232759.pdf (Publisher’s version ) (Closed access) In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Published: 2021

31. Associations Between Peripheral Blood Microbiome and the Risk of Hypertension

Author: Yang Jing, Jing Wu, Xiaofang Chen, Liangyue Zhou, Jingqi Zhang, Honghong Lu, Chen Dong, and Hui Zhou
Subjects: biology, business.industry, Microbiota, Physiology, Bacteroidetes, Odds ratio, biology.organism_classification, Confidence interval, Blood pressure, Cholesterol, Risk Factors, Case-Control Studies, Nested case-control study, Hypertension, Internal Medicine, Medicine, Humans, Microbiome, Prospective Studies, Prospective cohort study, business, Relative species abundance
Abstract: Background Although previous studies have reported the gut microbiome is closely related to hypertension development, whether the change in blood microbiome is associated with the risk of hypertension remains unclear. Methods One hundred and fifty incident hypertension cases and 150 age (± 2 years) and gender (1:1) matched nonhypertension controls included in this nested case–control study were recruited from a prospective cohort study of “135.” The composition of the blood microbiome was characterized using bacterial 16S ribosomal RNA gene sequencing. The relative abundance of detected bacteria was converted to a negative logarithm of 10 for the statistical analysis. Results Totally, 10,689,961 high-quality sequences were acquired. The Chao1 index of the blood microbiome in nonhypertension controls was significantly higher than in hypertensive group (2,302.08 ± 752.78 vs. 1,598.21 ± 500.88, P < 0.001). Compared with the nonhypertension controls, the relative abundance of Proteobacteria phylum was significantly increased (P < 0.001), whereas the relative abundance of phyla Firmicutes and Bacteroidetes were significantly reduced in the hypertensive cases (P < 0.001 and P = 0.039, respectively). At genus level, the risk of hypertension was directly associated with the relative abundance of Acinetobacter (odds ratio [OR]: 1.43, 95% confidence interval [CI]: 1.01–2.03), Sphingomonas (OR: 1.84, 95% CI: 1.32–2.56), and Staphylococcus (OR: 0.51, 95% CI: 0.36–0.73), respectively. In addition, the relative abundance of Pseudomonas was minor positively correlated with the total cholesterol level. However, the relative Staphylococcus level was minor positively correlated with high-density lipoprotein cholesterol level. Conclusions The composition of the blood microbiome is significantly associated with the development of hypertension.
Published: 2020

32. Design Research of Physical Virtual Experiment Based on Virtual Reality Technology

Author: Xing Ruonan, Yuan Jiugen, and Yang Jing
Subjects: Research design, Value (ethics), Imagination, Information Age, business.industry, Computer science, media_common.quotation_subject, Information technology, Space (commercial competition), Virtual reality, ComputingMilieux_COMPUTERSANDEDUCATION, Engineering ethics, business, Function (engineering), Construct (philosophy), media_common
Abstract: The advent of the information age has brought rapid development and progress to all walks of life in society. In this trend, information technology has gradually integrated into the education industry, and combined with various disciplines has brought a qualitative leap to education. Educational researchers and front-line teachers are currently paying attention to research topics. The physics experiment in the physics course is an important part of students' physics learning. However, in actual teaching, many middle schools have poor teaching effects due to limited experimental conditions and cannot meet the learning needs of each student. Virtual reality VR technology, as a technology with a wide imagination space function, can construct and produce physical phenomena that are difficult to observe in reality. This article attempts to design virtual reality (VR) technology for the application of physics experiments, and hopes to explore the value of virtual reality technology in physics experiment teaching.
Published: 2020

33. Teaching of Secretary Based on Mobile Phone Teaching Software Application

Author: Yang Jie and Yang Jing
Subjects: ComputingMilieux_THECOMPUTINGPROFESSION, Multimedia, business.industry, Computer science, Face (sociological concept), computer.software_genre, GeneralLiterature_MISCELLANEOUS, Software, Work (electrical), Teaching effect, Mobile phone, Vocational education, ComputingMilieux_COMPUTERSANDEDUCATION, Cellular network, business, computer
Abstract: With the rapid development of smart phones and mobile network technologies, modern secretarial work has begun to change, some skills are weakening, and some skills require higher and higher requirements. As a secretarial major, its practical teaching is to improve the professional teaching effect also brings new opportunities. In the face of this phenomenon, how vocational secretarial majors use smartphone software to improve the practice teaching system, so as to cultivate secretarial talents that meet the needs of the market in this era is worth pondering.
Published: 2020

34. Study on the application of network resources in home teaching

Author: Zhang Dongpo, Li Guoxia, Yang Jing, Mao Jianjing, and Sun Bin
Subjects: 2019-20 coronavirus outbreak, Government, Knowledge management, Coronavirus disease 2019 (COVID-19), business.industry, Computer science, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), media_common.quotation_subject, Blended learning, Tree (data structure), Promotion (rank), ComputingMilieux_COMPUTERSANDEDUCATION, Online teaching, business, media_common
Abstract: During the 2019-nCoV,in response to the government’s call to achieve “Suspended classes but non-stop teaching, suspended classes but non-stop learning”, family online teaching is carried out nationwide. By applying the resources of the Network Education Platforms such as Chinese University MOOC and Wisdom Tree, this paper discusses the important role of network resources in home-based teaching and the development prospects of promotion together.
Published: 2020

35. Clinical features and laboratory findings of SARS-CoV-2 infection in hospitalized patients

Author: Yunfang Xu, Yang Jing, Chen Dong, Yan Du, Lijuan Wang, Jingqi Zhang, Ming Yue, Jing Wu, Xingxiang Liu, and Yuanyuan Zhang
Subjects: medicine.medical_specialty, Hospitalized patients, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Internal medicine, Medicine, business
Abstract: Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a new emerging public health crisis to the world. However, data are still limited on the clinical features and laboratory findings in COVID-19 patients.Methods: Medical records including demographics characteristics, clinical features, laboratory findings and radiological materials of 66 hospitalized COVID-19 patients were collected between Jan 23 and Mar 9, 2020. Symptoms/signs with potential association with the disease severity were analyzed.Results: Of 66 hospitalized COVID-19 patients, the male-to-female ratio was 44:22. There were eight cases potentially exposed to one single patient. The most common initial symptoms of SARS-CoV-2 infection were fever (77.3%) and cough (74.2%). Compared to those with non-severe infection, the severe patients were more likely to be older (62.6 ± 15.1 vs 46.9 ± 13.3 years. P = 0.001) and with more infected lobes. As the results shown, higher initial (on admission) and peak (during hospitalization) counts of lymphocyte were inversely associated with the severe SARS-CoV-2 infection (both OR: 0.01 every 1´109/L decrease). However, the elevated initial neutrophil counts (OR: 1.63 every 1´109/L increase), initial and peak levels of LDH (OR: 1.02 and 1.01 every 1 U/L increase), peak levels of CRP (OR: 1.03 every 1 mg/L increase), AST (OR: 1.06 every 1 U/L increase) and ALT (OR: 1.02 every 1 U/L increase) were significantly associated with COVID-19 severity.Conclusion: Our present study indicated that fever and cough were the most common initial symptoms of SARS-CoV-2 infection, and the virus could be efficiently spread by person-to-person transmission. In addition, lymphocyte and neutrophil counts, and serum levels of AST, ALT, CRP and LDH should be useful for the evaluation on COVID-19 severity.
Published: 2020

36. Integrated Monitoring System of Intelligent Warehouse Based on Wireless Sensor Network

Author: Yang Jing, Wang xi-kun, Zhang Xiao-Han, and Wang yi-xin
Subjects: Java, business.industry, Computer science, Real-time computing, Warehouse, ALARM, Software, Data visualization, Systems architecture, Wireless, business, computer, Wireless sensor network, computer.programming_language
Abstract: We design a comprehensive monitoring system of intelligent warehouse. The system architecture is mainly divided into four parts: software monitoring, wireless sensor acquisition, water leakage detection and alarm, data curve display and query export. Through wireless sensor network technology and Java Web, real-time monitoring of warehouse temperature and humidity data is realized, and data visualization is realized through large screen.
Published: 2020

37. Association of hypertension with the severity and fatality of SARS-CoV-2 infection: A meta-analysis

Author: Chen Dong, Jianguo Shao, Ming Yue, Hong Xue, Jing Wu, Xiaohua Sun, Yang Jing, Jingqi Zhang, and Weihua Cai
Subjects: medicine.medical_specialty, hypertension, Coronavirus disease 2019 (COVID-19), Epidemiology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pneumonia, Viral, severity, Disease, 030204 cardiovascular system & hematology, Severity of Illness Index, 03 medical and health sciences, 0302 clinical medicine, fatality, Disease severity, Risk Factors, Internal medicine, Severity of illness, Medicine, Humans, 030212 general & internal medicine, Pandemics, Original Paper, business.industry, SARS-CoV-2, COVID-19, Publication bias, medicine.disease, Comorbidity, Infectious Diseases, Meta-analysis, business, Coronavirus Infections
Abstract: Hypertension is a common comorbidity in COVID-19 patients. However, the association of hypertension with the severity and fatality of COVID-19 remain unclear. In the present meta-analysis, relevant studies reported the impacts of hypertension on SARS-CoV-2 infection were identified by searching PubMed, Elsevier Science Direct, Web of Science, Wiley Online Library, Embase and CNKI up to 20 March 2020. As the results shown, 12 publications with 2389 COVID-19 patients (674 severe cases) were included for the analysis of disease severity. The severity rate of COVID-19 in hypertensive patients was much higher than in non-hypertensive cases (37.58%vs19.73%, pooled OR: 2.27, 95% CI: 1.80–2.86). Moreover, the pooled ORs of COVID-19 severity for hypertensionvs.non-hypertension was 2.21 (95% CI: 1.58–3.10) and 2.32 (95% CI: 1.70–3.17) in age vs.non-hypertension was 6.43 (95% CI: 3.40–12.17) and 2.66 (95% CI: 1.27–5.57) in age
Published: 2020

38. Dimensional Optimization for Minimally Invasive Surgery Robot Based on Double Space and Kinematic Accuracy Reliability Index

Author: Shi Xinge, Zhao Deming, Yang Jing, Jin Lingyan, and Hu Ming
Subjects: Computer science, business.industry, 0206 medical engineering, 02 engineering and technology, Kinematics, Space (mathematics), 020601 biomedical engineering, 030218 nuclear medicine & medical imaging, Computer Science::Robotics, 03 medical and health sciences, 0302 clinical medicine, Invasive surgery, Robot, Computer vision, Artificial intelligence, business, Reliability (statistics)
Abstract: To improve the kinematic performance of the remote center mechanism for surgical robot, a double space index and kinematic accuracy reliability index are proposed to optimize the dimensional sizes of mechanism. First, the influence of the angular error on the position error and the operability of the remote center in the workspace are analyzed. The position error space and operability space index are weighted to establish the double space index. Second, a kinematic accuracy reliability index is established based on the influence of joint clearance on output position accuracy. Finally, the dimensional sizes of remote center adjustment mechanism and double parallelogram mechanism are optimized based on proposed optimization indices. Multipopulation genetic algorithm is used to obtain the optimal size parameters under the corresponding index. The optimized double space index is 56.7%, which is 56.5% higher than before optimization. The optimized kinematic accuracy reliability is 0.91, which is 22.9% higher than before optimization. The kinematic performance of remote center mechanism has been significantly improved after optimization.
Published: 2020

39. Identification of hub genes and a prognostic model associated with ovarian cancer

Author: Wenjun Cheng, Jinhui Liu, Sipei Nie, Sun Rui, Siyue Li, pinping jiang, Huangyang Meng, and Yang Jing
Subjects: Hub genes, Text mining, genetic structures, business.industry, Prognostic model, medicine, Identification (biology), Computational biology, Biology, Ovarian cancer, medicine.disease, business
Abstract: Background: Ovarian cancer (OC) is one of the most lethal gynecological cancers worldwide. The pathogenesis of the disease and outcomes prediction of ovarian cancer patients remain largely unclear. This study aimed to explore the key genes and biological pathways in ovarian carcinoma development, as well as construct a prognostic model to predict patients’ overall survival. Results: We identified 164 up-regulated and 80 down-regulated differentially-expressed genes (DEGs) associated with ovarian cancer. GO term enrichment showed DEGs mainly correlated with spindle microtubes. For KEGG pathways, cell cycle was mostly enriched for the DEGs. The PPI network yielded 238 nodes and 1284 edges. Top three modules and 10 hub genes were further filtered and analyzed. Three candidiate drugs targeting for therapy were also selected. Thirteen OS-related genes were selected and an eight-mRNA model was present to stratify patients into high- and low-risk groups with significantly different survival. Conclusions: The identified DEGs and biological pathways may provide new perspective on the pathogenesis and treatments of OC. The identified 8-mRNA signature has significant clinical implication for outcome prediction and tailored therapy guidance for OC patients.
Published: 2020

40. Application of Quality Control Circle in Promoting the Use of Rubber Dams in the Root Canal Treatment of Primary Teeth

Author: Liu Qiong, Fang Jingxian, Song Yingying, Yang Jing, Liu Hedi, Liu Yang, Zhang Jinglan, Wu Xiaoming, Qian Hong, and Liu Fang
Subjects: Male, Quality Control, Article Subject, Root canal, media_common.quotation_subject, Rubber Dams, Dentistry, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Medicine, Operation time, Humans, Quality (business), 030212 general & internal medicine, Tooth, Deciduous, Child, Clinical treatment, media_common, General Immunology and Microbiology, business.industry, Pulpitis, 030206 dentistry, General Medicine, Chronic pulpitis, medicine.anatomical_structure, Female, business, Root Canal Preparation, Research Article
Abstract: Objective. Study the effect of quality control circle (QCC) in promoting the usage of rubber dams (RD) in root canal treatment of chronic pulpitis in primary teeth. Methods. Set up a quality control group to increase the amount of rubber dams used in the treatment of chronic pulpitis in primary teeth. Monthly monitoring results of the usage amount were counted by the outpatient computer system. Relevant data were collected through questionnaires, and causes of low utilization were analyzed, and the improvement measurements were formulated and implemented. Quality control circle activity was evaluated. Results. Through the quality control circle activity, the consumption of rubber dams in the root canal treatment of chronic pulpitis was significantly improved, children in treatment became more cooperative, and operation time of root canal treatment has also been shortened. Conclusion. The quality control circle activities played a significant role in promoting the use of rubber dams in the root canal treatment of primary teeth, and it can be used as a method to promote new clinical treatment programs.
Published: 2020

41. Study on the slagging of biomass briquette combustion

Author: Liu Fang, Ren Xiaoping, Yang jing, Sun Xiaoting, Tang Xintong, and Yang song
Subjects: Pollution, lcsh:GE1-350, Briquette, High energy, Waste management, business.industry, media_common.quotation_subject, 0211 other engineering and technologies, Biomass, 02 engineering and technology, 010501 environmental sciences, Combustion, Alternative fuels, 01 natural sciences, Environmental science, Coal, 021108 energy, business, lcsh:Environmental sciences, 0105 earth and related environmental sciences, media_common
Abstract: China’s coal-fired industrial boilers are characterized by high energy consumption, serious pollution, and large output of biomass briquette, which is a clean and high-quality alternative fuel to coal. However, there are serious slagging problems in combustion. Taking straw briquette as an example, this paper introduces its combustion characteristics, studies its slagging mechanism, slagging influencing factors, etc., reveals the slagging problems in essence, and provides theoretical basis for the prevention and control of slagging.
Published: 2020

42. M2 Macrophage-Derived Exosomal miR-31-5p Facilitates Oral Squamous Cell Carcinoma Tumourigenesis

Author: Hongming Du, Jiamin Xu, Lu Dai, Zhuoying Xie, Siyu Liu, Zeyu Wang, Yang Jing, Zhiyang Li, Youjin Dai, Yan Xia, Feng He, Yi Yuan, Juanyong Xu, Hongwei Li, Wei Shu, Jiaqing Wang, Pengfei Jiao, Yaqin Zhang, and Mengqi Chen
Subjects: Oncology, medicine.medical_specialty, business.industry, M2 Macrophage, medicine.disease_cause, Exosome, Microvesicles, mir-31, stomatognathic diseases, Informed consent, Internal medicine, microRNA, medicine, Basal cell, Carcinogenesis, business
Abstract: Clinical and investigational proof indicates that tumour-related macrophages stimulate tumour initiation and development. Consequently, macrophage-derived molecular factors controlling OSCC initiation are not yet completely understood. Here, we show that M2 macrophage–regulated OSCC cell growth and tumorigenicity depend on M2 macrophage-derived exosomes (M2 exo). M2 exo exhibited a high level of miR-31-5p, and the M2 exo-mediated increase in OSCC cell proliferation and growth depended on this miRNA. Mechanistically, miR-31-5p was delivered to OSCC cells through M2 exo and complementary pairing with the LATS2 coding sequence, thus suppressing the expression of LATS2, which has been considered to be a major aspect inhibiting OSCC growth. Collectively, our ﬁndings demonstrate that M2 exo participate in OSCC tumorigenesis, and M2 exo mediate their tumour-inducing effect via the miR-31-5p/LATS2 axis of the Hippo signalling pathway in OSCC. This active and mutual communication among OSCC cells and M2 macrophages provides a novel strategy for treating OSCC. Funding Statement: This work was supported by research grants from the National Natural Science Foundation of China (21872026), the Outstanding Young scholar Foundation of Jiangsu Province, China (BK20170106), the Major Projects of Science and Technology Development Fund of Nanjing Medical University (NMUD2019001), the Open Fund of State Key Laboratory of Pharmaceutical Biotechnology, Nan-jing University, China (KF-GN-201903), the Southeast University and Nanjing Medical University Cooperative Research Project, China (2019DN0003), the Open Research Fund of State Key Laboratory of Bioelectronics, Southeast University. Declaration of Interests: None. Ethics Approval Statement: The study procedure was under the approval of the Ethics Committee of Stomatology Hospital Affiliated to Nanjing Medical University, and written informed consent was obtained from every patient.
Published: 2020

43. A generalized channel preemption model for multiclass traffic in mobile wireless networks

Author: Sheu, Tsang-Ling, Wu, Yang-Jing, and Li, Bo
Subjects: Markov processes -- Analysis, Communications traffic -- Management, Mobile communication systems -- Research, Wireless communication systems -- Research, Multicasting, Wireless technology, Company business management, Business, Electronics, Electronics and electrical industries, Transportation industry
Abstract: This paper presents a generalized channel preemption model (GCPM) for multiclass traffic in mobile wireless networks. In the proposed model, a mobile call is identified by four parameters--call type, traffic class, channel requirement, and preemption ratioi--in which different classes of traffic can have different priority levels. To effectively reduce dropping probability, high-priority handoff calls are allowed to fully or partially preempt low-priority ongoing calls when the mobile network becomes congested. A fully preempted call can be completely disconnected, whereas a partially preempted call can still communicate with certain degree of quality-of-service degradation. We introduce an analytical model with multidimensional Markov chains. In the model, a cost function, which is expressed as a weighted sum of the ongoing calls to be preempted and the bandwidth reduction rate in the preempted calls, is defined to select candidate calls from a certain traffic class. The statistical result from the model allows us to tune the parameters of the GCPM to support high-priority handoff calls and therefore offers new insights in understanding the tradeoffs in supporting multiclass traffic. Index Terms--Channel preemption, handoff calls, Markov chains, mobile wireless networks.
Published: 2007

44. Do Share Buybacks Provide Price Support? Evidence From Mandatory Non-Trading Periods

Author: Keswani, Aneel, Yang, Jing, and Young, Steven
Subjects: Banking, finance and accounting industries, Business
Abstract: To purchase or authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1468-5957.2007.02009.x Byline: Aneel Keswani (1), Jing Yang (1), Steven Young (1) Keywords: open market share repurchases; close period; price manipulation Abstract: Abstract: Financial regulators, analysts and journalists have expressed concern that open market share repurchases may help support share prices. We test this conjecture by examining repurchasing firms' share price patterns on entering mandatory non-trading periods imposed by the London Stock Exchange. If buybacks provide price support, we would expect to observe price declines when trading bans force firms to suspend their buyback program. Consistent with claims that open market buybacks provide price support, we document average price declines when repurchasing firms enter mandatory non-trading periods. We also find that the magnitude of the price decline varies cross-sectionally with proxies for the price support impact of repurchases in the predicted manner. However, economic and statistical significance levels are moderate and largely confined to non-trading periods preceding interim results announcements, casting doubt on whether trading profits could be earned by exploiting this information. Author Affiliation: (1)The first author is from Cass Business School, London. The second and third authors are from the Department of Accounting & Finance, Lancaster University. They thank Meziane Lasfer and an anonymous referee for helpful comments and suggestions. Research assistance was provided by Ashish Agrawal, Anuradha Jayaraman, Valentine Ururka and Idlan Zakaria. Financial support was provided by the Economic and Social Research Council (contract R000223516) and The Leverhulme Trust (project reference F/00185/I). Article History: (Paper received January 2005, revised version accepted August 2006. Online publication April 2007) Article note: (*) Address for correspondince: Aneel Keswani, Cass Business School, 106 Bunhill Row, London EC1Y 8TZ, UK. e-mail: a.keswani@city.ac.uk
Published: 2007

45. Network models and financial stability

Author: Nier, Erlend, Yang, Jing, Yorulmazer, Tanju, and Alentorn, Amadeo
Subjects: Business, Economics
Abstract: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jedc.2007.01.014 Byline: Erlend Nier (a), Jing Yang (a), Tanju Yorulmazer (a), Amadeo Alentorn (b) Abstract: Systemic risk is a key concern for central banks charged with safeguarding overall financial stability. In this paper we investigate how systemic risk is affected by the structure of the financial system. We construct banking systems that are composed of a number of banks that are connected by interbank linkages. We then vary the key parameters that define the structure of the financial system - including its level of capitalisation, the degree to which banks are connected, the size of interbank exposures and the degree of concentration of the system - and analyse the influence of these parameters on the likelihood of knock-on defaults. First, we find that the better capitalised banks are, the more resilient is the banking system against contagious defaults and this effect is non-linear. Second, the effect of the degree of connectivity is non-monotonic, i.e. initially a small increase in connectivity increases the contagion effect; but after a certain threshold value, connectivity improves the ability of a banking system to absorb shocks. Third, the size of interbank liabilities tends to increase the risk of knock-on default, even if banks hold capital against such exposures. Fourth, more concentrated banking systems are shown to be prone to larger systemic risk, all else equal. In an extension to the main analysis we study how liquidity effects interact with banking structure to produce a greater chance of systemic breakdown. We finally consider how the risk of contagion might depend on the degree of asymmetry (tiering) inherent in the structure of the banking system. A number of our results have important implications for public policy, which this paper also draws out. Author Affiliation: (a) Bank of England, Threadneedle Street, London EC2R 8ah, UK (b) University of Essex, UK Article Note: (footnote) [star] This paper reflects the views of the authors only and not necessarily those of the Bank of England or any other members of its staff.
Published: 2007

46. Unidirectional Absorption in a Three-Dimensional Tunable Absorber Under Oblique Incidence

Author: Zhang Hao, Haifeng Zhang, Yang Jing, and Hai-Ming Li
Subjects: Materials science, business.industry, Biophysics, Metamaterial, 02 engineering and technology, Plasma, 021001 nanoscience & nanotechnology, 01 natural sciences, Biochemistry, Electromagnetic radiation, Spectral line, 010309 optics, Resonator, Transmission (telecommunications), Excited state, 0103 physical sciences, Optoelectronics, 0210 nano-technology, business, Absorption (electromagnetic radiation), Biotechnology
Abstract: In this paper, we propose a three-dimensional tunable absorber to realize a controllable unidirectional absorption and unidirectional transmission based on the plasma metamaterial, which includes two metamaterial layers that are vertical to each other. Each side of the proposed absorber integrates two split-ring resonators, which are made in the solid-state plasma (SSP). Unidirectional absorption and unidirectional transmission can be achieved when the incident angle of the electromagnetic wave is 30°. Furthermore, the unidirectional absorption and unidirectional transmission can be manipulated through exciting the different SSP resonators and adjusting the positions of the corresponding gaps between the two SSP resonators. In addition, the tunable absorption and transmission spectra can be obtained when the different SSP resonators are excited.
Published: 2018

47. Yearly Variation of Growth and Yield of Waxy Maize (Zea mays L.) and Soil Characteristics under Organic Rice Paddy-Upland Rotation

Author: Seong-Tak Yoon, Yang， jing, and Woo-Jin Jung
Subjects: Soil characteristics, Yield (engineering), Agronomy, Agriculture, business.industry, Organic farming, Environmental science, Paddy field, business, Rotation, Zea mays
Published: 2018

48. A Band Enhanced Tunable Ultra-Broadband Absorber Based on Loading the Lumped Resistors and Cavity Resonance

Author: Liu Jiaxuan, Yu Ma, Yang Jing, Haifeng Zhang, and Zhang Hao
Subjects: Materials science, business.industry, Biophysics, 02 engineering and technology, 021001 nanoscience & nanotechnology, 01 natural sciences, Biochemistry, Electromagnetic radiation, Spectral line, law.invention, 010309 optics, Resonator, law, Electric field, 0103 physical sciences, Broadband, Optoelectronics, Resistor, 0210 nano-technology, business, Absorption (electromagnetic radiation), Layer (electronics), Biotechnology
Abstract: In this paper, we present and demonstrate a band enhanced tunable ultra-broadband absorber (TUA) based on loading the lump resistors (LRs) and cavity resonance. The absorber’s each cell integrates four split ring-shaped solid state plasma resonators (SSPRs) which are connected by the solid state plasma (SSP) bars separately. The four split ring-shaped SSPRs and external truncated SSP bars are loaded with lump elements, respectively. The entire structure also comprises the dielectric substrate and continuous metallic layer. By simulations, the ultra-broadband absorption goes beyond 90% in the frequency region 11.13–19.81 GHz is realized through loading LRs and cavity resonance. Moreover, the absorber also is polarization-independent for the incident electromagnetic wave. It is remarkable that the absorption bandwidth is further promoted by inserting the air cylinders (ACs). The absorption also is investigated for oblique incidence, which shows that the proposed TUA can work over a wide incident angle. We focus on the distribution of surface current, the electric field, and power loss density to elucidate the physical mechanism. In addition, the tunable spectra can be obtained in such TUA by exciting the different SSPRs.
Published: 2018

49. A Band Enhanced Plasma Metamaterial Absorber Based on Triangular Ring-Shaped Resonators

Author: Yang Jing, Liu Jiaxuan, Zhang Hao, Yi Yao, and Haifeng Zhang
Subjects: lcsh:Applied optics. Photonics, Materials science, Astrophysics::Cosmology and Extragalactic Astrophysics, 02 engineering and technology, Absorber, 01 natural sciences, 010309 optics, Absorption rate, Resonator, 020210 optoelectronics & photonics, Electric field, 0103 physical sciences, Broadband, 0202 electrical engineering, electronic engineering, information engineering, lcsh:QC350-467, Electrical and Electronic Engineering, business.industry, Bandwidth (signal processing), lcsh:TA1501-1820, Metamaterial, Plasma, Atomic and Molecular Physics, and Optics, plasma metamaterials, Metamaterial absorber, Optoelectronics, tunability, business, lcsh:Optics. Light
Abstract: In this paper, a novel way is proposed to realize a broadband absorber, which is based on the plasma metamaterial with the triangular ring-shaped resonators. Each unit cell of the proposed absorber includes three layers, which are metal layer, dielectric layer, and solid-state plasma (SSP) layer, respectively. The top layer is composed of the truncated SSP triangular ring-shaped resonators and the SSP triangular patches, which are situated the middle of triangular rings. An SSP cylinder also is inserted between the central of each SSP triangular patch and the bottom metal layer. The absorption bandwidth can be covered from 11.76 to 14.43 GHz when the absorption rate is larger than 90%, which also is polarization-independent. In addition, the better performances can be realized under different incident angles. To explain the mechanism of high absorption, the electric field, the surface current distribution, and power loss density at different resonant frequencies are present. Moreover, the tunable absorption can be obtained in the proposed absorber while the performance of the absorber can be improved by exciting the different SSP resonators.
Published: 2018

50. A review of sublethal effects of pulsed electric field on cells in food processing

Author: Alaa El-Din A. Bekhit, Wang Mansheng, Xin-An Zeng, Yan-Zhou Wang, Lang-Hong Wang, Qiu-Zhong Dai, Yang Jing, and Zhen-Ping Hou
Subjects: 0106 biological sciences, Food industry, Chemistry, business.industry, Pasteurization, 04 agricultural and veterinary sciences, respiratory system, Bactericidal effect, Food safety, 040401 food science, 01 natural sciences, respiratory tract diseases, law.invention, On cells, 0404 agricultural biotechnology, immune system diseases, law, 010608 biotechnology, Food processing, Food science, business, circulatory and respiratory physiology, Food Science
Abstract: Pulsed electric field (PEF) treatment, a novel technology which has an electroporation effect on cells, has a wide range of practical applications, especially in the food industry. Because of their varying susceptibility to PEF, cells exhibit one of three possible states after PEF treatment: dead, intact or sublethally injured. This review article summarizes the relevant references, focusing on the sublethal effects of PEF treatment of cells during food processing. The protective and metabolic mechanisms involved associated with the phenomenon of sublethal effects are featured. In addition, some useful methods which could be combined with PEF to enhance the bactericidal effect are discussed in detail. In summary, PEF technology holds great promise as a widely applicable, safe method for food pasteurization.
Published: 2018

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