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Despite significant advances, the therapeutic impact of photodynamic therapy is still substantially hampered by the restricted penetration depth of light and the reactive oxygen species (ROS)-mediated toxicity, which is impeded by the shorter effective half-life and radius of ROS produced during treatment. Sonodynamic therapy (SDT), on the other hand, provides unrivalled benefits in deep-seated tumour ablation due to its deep penetration depth and not totally ROS-dependent toxicity, exhibiting enormous preclinical and clinical potential. In this tutorial review, we highlight imaging-guided precise SDT, which allows choosing the best treatment option and monitoring the therapy response in real-time, as well as recent clinical trials based on SDT. Aside from that, the subtle design strategies of sonosensitizers based on tumour environment shaping and rational structure modification, as well as SDT combination treatment (chemotherapy, chemodynamic therapy, photodynamic therapy, photothermal therapy, gas therapy and immunotherapy), aimed at a more effective treatment outcome, are summarized. Finally, we discussed the future of SDT for personalized cancer and other disease treatments.

In order to better realize rural revitalization and promote the development of agriculture in the direction of intelligence and efficiency, people need to combine the Internet of Things technology with rural revitalization. Moreover, as the Internet of Things technology continues to improve, its role will become more and more obvious. This article summarizes the problems existing in the process of rural revitalization based on previous work experience. The author discusses the application prospects of the Internet of Things technology in rural revitalization from five aspects: Internet of Things smart agriculture, smart elderly care and medical care, Internet of Things course education, technology integration, and science and technology to promote agricultural modernization.

Based on quasicontinuum (QC) multiscale simulation method, a series of simulation models were set up for bending and compressing rod-shaped microstructure of single crystal Cu. The effects of structural parameters on typical mechanical properties were analyzed, such as elastic modulus, elastic limit, yield strength, and Poisson’s ratio. According to the analysis of displacement, inner stress and strain energy, the mechanisms of deformation and failure were also revealed. The experimental result shows that the mechanical properties exhibit obvious size effect during the bending and compression process. In the bending simulation, when the span-thickness ratio is more than 10, the elastic modulus rises slightly with the increase of strain. And the smaller the beam is, the faster the elastic modulus grows. Meanwhile, when the span-thickness ratio keeps constant the elastic modulus will decrease with the growth of the beam sizes. However, in the compression model, the size effect on Poisson’s ratio is not remarkable. The dimensional change in one direction cannot influence the mechanical parameters greatly. Mechanical twins and dislocation contribute to the compression behaviour greatly. Meanwhile, the stress concentration can also be found in the inner partial area and the strain energy decreases abruptly after the crush of beam microstructure.

Yin, L. and Zhang, X., 2020. Green and quality development of service industry in West Coast Economic Zone. In: Yang, Y.; Mi, C.; Zhao, L., and Lam, S. (eds.), Global Topics and New Trends in Coastal Research: Port, Coastal and Ocean Engineering. Journal of Coastal Research, Special Issue No. 103, pp. 1158–1161. Coconut Creek (Florida), ISSN 0749-0208.Thanks to the increasing-broadened scale of foreign investment, the orderly and green development of service industry in the West Coast Economic Zone has promoted the traditional service industry to emerge as the pillar of the tertiary industry in recent years. However, this zone also witnessed the poor internal structure of the service industry, non-quality employees, incomplete green development system of service industry, residents' weak consciousness of green production of enterprises and green consumption and loose green management, etc. In this regard, measures should be taken to optimize the internal structure of the service industry, create green growth points, and activate the market by developing green service industry agglomeration areas. In addition, it is necessary to ensure the elements of green development of service industry and deepen cooperation with Taiwan's service industry, so as to advance the green and high-quality development of service industry in the West Coast Economic Zone.

Yu, J.; Shen, H.; Gou, J., and Zhang, X., 2020. The green environment measurement by entropy method: A study based on Minnan Coastal Area in China. In: Yang, Y.; Mi, C.; Zhao, L., and Lam, S. (eds.), Global Topics and New Trends in Coastal Research: Port, Coastal and Ocean Engineering. Journal of Coastal Research, Special Issue No. 103, pp. 442–446. Coconut Creek (Florida), ISSN 0749-0208.The Minnan area is located in the east of Fujian Province, close to the mountains and the sea, with superior geographical position and good ecological environment. It is the pioneer of green development in Fujian Province. Entropy method is a comprehensive evaluation index method of objective weighting, which has been widely used in the field of ecological environment. In this study, we use entropy method to calculate the environmental development level of Minnan area. Through the analysis of the empirical results of green environment development, we found that the level of green development in Xiamen is higher than that in Quanzhou, Zhangzhou, and the three cities in Minnan area are all inclined to the development of economic indicators. To this end, we suggest that the three cities in Minnan area should pay attention to the coordinated development of economic indicators, social indicators and environmental indicators, strengthen cooperation among the three cities, and generate useful insight for relevant departments to create a new development path of green industry.

For embedded system vulnerability mining technology, due to the dependence of the program on the hardware environment, the efficiency of traditional fuzz embedded program is very low, and it is difficult to cover some program execution path, which seriously affects the efficiency and quality of the embedded program for vulnerability mining. The paper presented an embedded system vulnerability mining technology based on a memory fuzz test. It can directly test any part of program without the restrictions. In addition, the fuzzing test is done directly in memory, without any unrelated interface, which can greatly improve the efficiency of fuzzing test for the embedded procedures.

UPnP (Universal Plug and Play) protocol has been frequently applied to the Internet gateway device. However, with the gateway device becoming intelligent, UPnP generated more and more security issues. Therefore, the current research aims to introduce the workflow of UPnP protocol in gateway equipment, analyze the security problems existing in some workflows and realize a set of UPnP detection and utilization system for UPnP in the application of gateway device.

Owing to the shortages of inconvenience, expensive and high professional requirements etc. for conventional recognition devices of wheat leaf diseases, it does not satisfy the requirements of uploading and releasing timely investigation data in the large-scale field, which may influence the effectiveness of prevention and control for wheat diseases. In this study, a fast, accurate, and robust diagnose system of wheat leaf diseases based on android smartphone was developed, which comprises of two parts—the client and the server. The functions of the client include image acquisition, GPS positioning, corresponding, and knowledge base of disease prevention and control. The server includes image processing, feature extraction, and selection, and classifier establishing. The recognition process of the system goes as follow: when disease images were collected in fields and sent to the server by android smartphone, and then image processing of disease spots was carried out by the server. Eighteen larger weight features were selected by algorithm relief-F and as the input of Relevance Vector Machine (RVM), and the automatic identification of wheat stripe rust and powdery mildew was realized. The experimental results showed that the average recognition rate and predicted speed of RVM model were 5.56% and 7.41 times higher than that of Support Vector Machine (SVM). And application discovered that it needs about 1 minute to get the identification result. Therefore, it can be concluded that the system could be used to recognize wheat diseases and real-time investigate in fields.

Effective motivational mechanism can stimulate the potentiality of knowledgeable talents. Based on the organizational commitment the paper discusses the factors affected the motivation of knowledgeable talents. They include internal motivation factors such as working, individual growth, achievement needs and external motivation factors, such as compensation, high autonomy, recognition by others and so on. The paper puts forward the “hardcore” theory, builds motivation model for the motivation of knowledgeable talents based on organizational commitment, and proposes to improve organizational commitment of talented knowledgeable talents by enhance internal and external motivation factors, and then, to promote organizational development.

Employee conflict management is an important content. We center on environment,organization, leadership, human nature (EOL-H) of employee relationship management to analyze the conflict, by which we found a framework for conflict management mechanisms. We also put forward that enterprises should make conflict management become a cycling management mechanism, and realize enterprise to achieve the harmonious state of employee relations when it pay great attention to the use of the target, resources, and the enterprise culture, leadership of the conflict resolution.

For Chinese Education global demand and "Chinese fever" warming up in the world, further study on Chinese Education is a big subject in the new situation. Regard the aim of Chinese Education as the starting point, construct evaluation index system and theoretical framework of Chinese Education, Provide a solid theoretical support and development of power for follow-up research and rapid development of Chinese Education.

The public employment training is the important path to increase human resource character. Now Fujian province public employment train exsits government management working talent is not pure, the funds input is not enough, the training market is not the norm ect. Bring upping it must guarantee from lawmaking; perfect government management; Many ways to gather funds; Enhance the training evaluation; Establish the mechanism system of public employment training; to encrease the economic zone of west coast the public employment level, to promote the the economic zone of west coast economy science development.

As the coming of knowledge economy era, Knowledge Workers becomes the most important resource of Private Small and Medium Enterprises. Knowledge workers in Chinese Private Small Enterprises of and Medium growth direction can be divided into: Lengthways growth, Horizontal growth and Core. At present Knowledge Workers in Chinese Private Small and Medium Enterprises Growth of the main obstacle: Management mechanism under-developed; The salary management problems; Limit decision ability of Knowledge Workers; The very small opportunity of training and education; The work challenge shortage. To bring up how to manage the Private Enterprises knowledge workers, such as: Adopt the forerunner's management principle; Leading overall salary system; Let Knowledge Workers more participation management decision; The perfect training mechanism; Provide personal development challenge space, and so on.

Chinese traditional culture ≪LaoZi≫ is also name ≪DaoDeJing≫, this book has the abundant management thinking, we can apply it in the modern time human resource of the business enterprise, it benefit to know the human resource management methods, Pay attention to the human resource's management foundation, Fully draw lessons and the techniqu from the human resource the management.

This paper redefine the intelligence capital function, it point out the intelligence capital to have the material, the spirit, policy function etc. it set up the molds to analysis the central government, local government, individual intelligence capital investment policy, and find the central government must according to the local government investment hobby, individual actual condition, the government subsidize lead the various investment on the intelligence capital.

The study concludes the factors influencing knowledgeable talents performance contain personal factors and organizational factors. In this thesis we have found that the interaction in different dimensions of organizational commitment has influence on knowledgeable talents performance and build models for knowledgeable talents performance. Meanwhile this paper puts forward to promote knowledge talents performance through implementing incentive measures to stimulate work motivation, offering learning and training opportunities to improve productive capacity, authorizing fully to offer organizational support, and creating cooperative and shared organizational climate.