1. Effect of Infusion Rate on Thiopental Dose-Response Relationships
- Author
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Tom C. Krejcie, Michael J. Avram, W. B. Gentry, Colin A. Shanks, Dhanesh K. Gupta, K. Howard, and Thomas K. Henthorn
- Subjects
Pharmacokinetic pharmacodynamic ,business.industry ,Pharmacology ,Dose–response relationship ,Anesthesiology and Pain Medicine ,Anesthetic induction ,Pharmacokinetics ,Pharmacodynamics ,Reference values ,Anesthesia ,Total dose ,Medicine ,business ,Thiopental Dose - Abstract
BackgroundThe rate of administration of an intravenous anesthetic induction agent is an important variable determining the total dose required to reach a given endpoint, such as loss of consciousness (LOC). The influence of infusion rate on the dose-response relationship has not been described rigor
- Published
- 1994
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