We have already entered into the so called VUCA World, a world of tumult, new technologies, and a new generation of employees. HR departments need to revise their mission, vision, strategies, and tools to answer to these new challenges. The main aim of this chapter is to evaluate, through an in-depth bibliographical analysis and an Italian case study, how HR departments can be supported in their strategic reflection by using a structured approach to becoming more effective in this VUCA World. Moreover, the chapter contributes to making HR managers and HR professionals aware of the HR Strategic Forum, a method that could help them to define in a shared way what the main pillars of the HR function are. These mainstays should never be forgotten, especially in times of constant change, such as the ones we are currently experiencing.