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The race is on as several drugmakers get closer to the finish line in developing the first Bruton tyrosine kinase (BTK) inhibitor to treat multiple sclerosis (MS). BTK is a [...]

These days, glucagon-like peptide 1 (GLP-1) receptor agonists need no introduction; they are the hot topic in professional meetings and conferences, in Hollywood and on TikTok Part of abroader class [...]

The antibody-drug conjugate (ADC) class has seen substantial growth since the first FDA approval of an ADC, Pfizer's Mylotarg (gemtuzumab ozogamicin), in 2000. Mylotarg, which was used to treat patients [...]

Janus kinases (JAKs) are a group of inflammatory proteins associated with the pathogenesis of several inflammatory and autoimmune disorders, including skin conditions such as atopic dermatitis, vitiligo, alopecia areata and [...]

After going dormant for decades because of government restrictions, research focusing on the use of psychedelics for the treatment of psychiatric conditions has sprung to life. Research conducted in this [...]

Triple-negative breast cancer accounts for about 15% of breast cancers and is considered the most aggressive type, with a five-year survival rate of approximately 30%. The four-year survival rate for [...]

Before December 2020, when the FDA authorized the use of two COVID-19 messenger RNA (mRNA) vaccines developed by Pfizer and Moderna, the science behind mRNA vaccines had been researched for [...]

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer in the United States, accounting for about 85% of all lung carcinomas. It is the leading cause [...]

The emergence of the SARS-CoV-2 virus in late 2019 prompted drug manufacturers, biotechnology companies and laboratories to swing into action to develop agents that would neutralize the virus and prevent [...]

In the United States, breast cancer is second only to skin cancer as the malignancy most commonly diagnosed among women. Nearly 300,000 women will be diagnosed with invasive breast cancer [...]

First discovered approximately 60 years ago, lipoprotein(a) is a variant of low-density lipoprotein. Elevated lipoprotein(a), which experts often refer to as 'L-P-little-a,' has been associated with an increased risk of [...]

Duchenne muscular dystrophy (DMD) is a progressive, X-linked genetic disorder primarily affecting boys. It is the most common form of childhood muscular dystrophy, affecting about 1 in 3,500 male births [...]

Respiratory syncytial (pronounced sin-SISH -shul) virus (RSV) is a highly contagious virus that can affect the lower respiratory tract and is a leading cause of pneumonia and other respiratory tract [...]

The current landscape in hemophilia treatment looks quite different than it did decades ago when plasma-derived clotting factor replacement therapy was the standard of care. Recent advances have introduced extended [...]

TUMOR NECROSIS FACTOR-ALPHA (TNF-ALPHA) blockers are biologics typically prescribed to treat various inflammatory autoimmune conditions, including ulcerative colitis. Specifically, Remicade (infliximab and biosimilars) and Humira (adalimumab and biosimilars) are FDA-approved [...]

Multiple sclerosis (MS) is about three times more prevalent in women than men, and hormonal differences are believed to be the culprit. Research suggests, for example, that MS symptoms may [...]

Alzheimer's disease is the most common type of dementia, affecting more than 6 million people in the United States. According to the Alzheimer's Association projection, by 2050 Alzheimer's disease is [...]

Ulcerative colitis and Crohn's disease are the two most common inflammatory bowel diseases. Ulcerative colitis is characterized by chronic inflammation and ulceration of the colon mucus membrane, resulting in symptoms [...]

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative, fatal disease affecting motor neurons that control voluntary muscle movement. Initial symptoms can include muscle cramping, twitching, [...]

Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease (NAFLD). It is considered the second phase of NAFLD and is characterized by hepatic inflammation and ballooning due [...]

Post-traumatic stress disorder (PTSD) is a chronic psychiatric condition that occurs in some people after experiencing or witnessing traumatic events, such as military combat trauma, childhood trauma and physical or [...]

Hemophilia is a rare, X-linked, hereditary bleeding disorder characterized by blood clotting factor deficiencies that affects mainly males. It results in excessive bleeding, particularly in the joints, soft tissues and [...]

Asthma is a chronic respiratory disease that causes narrowing and inflammation of the airways that compromises breathing and, in some cases, can be fatal. Symptoms include coughing, wheezing, shortness of [...]

Antibody-drug conjugates (ADCs) are oncology drugs that have been compared to guided missiles because they home in on certain cell-surface targets and then unleash toxic chemotherapy drugs to battle cancer [...]

Atopic dermatitis (AD), also known as eczema, is a chronic inflammatory skin condition affecting up to 10% of adults and 20% of children in the United States. It is characterized [...]

Multiple sclerosis (MS) is a progressive autoimmune disease that affects nearly 1 million people in the United States. The debilitating disorder is characterized by lesion formation throughout the central nervous [...]

Macrophages, which are cells that engulf or 'eat' other cells, are key players in the body's immune response. But they need some guidance. Checkpoints built into human cells keep macrophages [...]

People with plaque psoriasis have a number of treatment options: topical agents, phototherapy, oral treatments and biologies. And now drugmakers are vying to create even more. In front of the [...]