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To evaluate the effects of textured insole socks on balance, gait parameters, and fall risk in older adults at risk of falling.Thirty older adults at risk of falls participated and were randomly al...

This study sought to investigate the effects of foam pad balance exercises on balance, physical performance, peripheral neuropathy symptoms, and quality of life in cancer patients undergoing taxane-based chemotherapy.Thirty cancer patients receiving chemotherapy were randomly divided into 2 groups (n = 15/group): control group (CG) and balance exercise group (BG). The BG were asked to perform foam pad balance exercises 60 min/day, twice/week for 6 weeks, along with conventional therapy. The CG only received conventional therapy. The Fullerton Advanced Balance (FAB) Score, Short Physical Performance Battery (SPPB), Michigan Diabetic Neuropathy Score (MDNS), and Functional Assessment of Cancer Therapy-Taxane (FACT-Taxane) were used to assess balance, physical performance, peripheral neuropathy symptoms, and quality of life, respectively, at baseline and after 4 and 6 weeks of treatment.At 4 and/or 6 weeks, the CG showed a decline in FAB and SPPB Scores, while the BG maintained their baseline levels. There were significant differences in the FAB Scores between the groups at the 4th and 6th week (p = 0.04 and p 0.01, respectively) and significant differences in SPPB Scores at only the 6th week (p = 0.03). MDNS showed no significant changes between or within groups. For FACT-Taxane between groups, the CG and BG showed significant decreases (p 0.01) and increases (p 0.01), respectively, at 6th week.Foam pad balance exercises during chemotherapy can be used to alleviate declining balance and enhance physical performance and quality of life of cancer patients.

Background/Aims Balance training using unstable support surfaces is widely used in clinics and research and can reduce the risk of falls in older people. This study aimed to investigate the effect of an exercise programme using a foam bead bag on older adults' ability to balance and the strength of their lower extremities and compare the effect with no exercise and foam pad exercise using the same programme. Methods A total of 24 older adults were allocated into one of three groups: control (n=8), foam pad exercise (n=8) and foam bead bag exercise (n=8). The foam pad exercise and foam bead bag exercise groups carried out a programme consisting of 30 minutes of exercise performed twice a week for 5 weeks. The control group did not participate in an exercise programme. Participants' balance abilities were measured using the Fullerton Advanced Balance Scale, the Timed Up and Go Test and the Single-Leg Stance Test. The strength of their lower extremities was measured using the 30-second sit-to-stand test. Results The Fullerton Advanced Balance scale and 30-second sit-to-stand scores significantly improved in the foam pad exercise and foam bead bag exercise groups. Both of these groups also demonstrated significant improvements in Timed Up and Go tests. The amount of time that participants were able to stand on one leg while unassisted significantly increased in the foam bead bag group only. No significant differences were found in balance ability or lower extremity strength in the control group. Conclusions A foam bead bag is a suitable alternative to a foam pad when performing exercises to improve balance and strength of the lower extremities in older adults.

Background Plantar fasciitis (PF) is the most common cause of heel pain. A calf stretching (CS) and a plantar fascia-specific stretching (PFSS) are two stretching techniques commonly administered by health care providers. Objective To evaluate the literature on the application of these two stretching techniques in the treatment of PF and investigate their effectiveness and efficacy. Method A search of PubMed, Web of Sciences, PEDro, CINHAL and Scopus was conducted. Studies that applied stretching as a co-intervention were excluded. The risk of bias was assessed to determine the internal validity of the included trials. The GRADE approach was adopted to determine the overall quality. Pooled analysis was performed to determine the treatment effects of CS and PFSS in terms of the mean difference in the visual analog scale pain score. Results Eight articles were found that represented randomized controlled trial and met the inclusion criteria. There was very low-quality evidence that the combined CS and PFSS was less effective in the short term than the other therapies. Comparison between CS and PFSS revealed moderate quality evidence for a larger effect of pain score reduction for PFSS treatment over CS, while very low-quality evidence supported that combined CS and PFSS or CS alone was superior to sham stretching. Conclusion There was moderate to very low-quality evidence of the effectiveness of stretching for PF. The treatment effect of stretching was large and comparable to other therapies. Future trials of higher quality are needed to clarify findings or to confirm findings.

Background Postural stability during sit-to-stand (STS) movements depends on visual and somatosensory information. A modification of the 30-sec chair-stand test (30s-CST) with visual and somatosensory alteration (m30CST) may improve the ability to identify fall status. Objective This study aimed to investigate the accuracy of the m30CST in predicting falls in older adults. Methods This prospective cohort study recruited a convenience sample of 73 individuals from Kao Kilo community, Chonburi, Thailand. Eligibility criteria were age ≥ 65 years and independent STS ability. All participants performed the 30s-CST and m30CSTs (i.e., eyes closed and a foam surface and eyes closed and a foam surface). The fall incidence during a 6-month follow-up was recorded. The area under the receiver operating characteristic curve (AUC) was calculated. Twenty participants were designated for reliability and validity analyses using the 30s-CST and the Fullerton Advanced Balance (FAB) Scale, estimating intraclass correlation coefficients (ICCs). Results We included 37 fallers and 36 non-fallers. All tests showed excellent accuracy in classifying fallers (AUC = 0.77–0.91). The m30CST with eyes closed and a foam surface had the highest AUC (0.91), with a cutoff score of 9.25 repetitions, sensitivity 92%, and specificity 81%. The m30CSTs presented excellent inter-rater reliability (ICC = 0.93–0.96) and test–retest reliability (ICC = 0.90–0.96), good to excellent correlation with the 30s-CST (r = 0.90–0.98), and moderate to good correlation with the FAB Scale (r = 0.64–0.73). Conclusions The m30CST could be used as an alternative evaluation for predicting the risk of falls in community-dwelling older adults, with excellent accuracy.

Exposure to PM10 generated by biomass burning may reduce lung function and induce cytogenetic effects, especially in chronic obstructive pulmonary disease patients. This study investigated the frequency of DNA-damaged cells, cells with cytokinetic defect, and different types of cell death using a buccal micronucleus cytome assay. The correlations between each biomarker and lung function were investigated. The changes in these biomarkers associated with high pollutant levels (PM10 > 50 μg/m3) and low pollutant levels (PM10

Background: Functional impairment of the muscle-tendon unit is one of the most remarkable effects of aging. The function of the peroneus longus muscle is to stabilise the foot and ankle joint. A deterioration of the structural and mechanical properties of this muscle can potentially lead to foot problems in older adults. This study aimed to investigate the effects of age on structural, histological, and mechanical features in peroneus longus muscle samples taken from embalmed cadavers of two different age groups; young adult (30–60 years) and old adult (over 60 years). Materials and methods: The mechanical property was analysed through the results of cross-sectional area, tensile, tensile stress, and modulus of elasticity. The arran- gement of the collagen in the perimysium and tendon was examined by scanning electron microscopy. Fatty infiltration within the musculotendinous junction was evaluated by Masson’ trichrome stained muscle sections. Results: This study thus provides evidence that there are indeed age-induced mechanical property changes in the peroneus longus muscle, which include reductions in the tensile force, tensile stress, and modulus of elasticity, and is related to the malformation of collagen fibrils and the massive fat accumulation in the musculotendinous junction. Conclusions: These alterations may further result in a reduction of muscle strength and quality in an older person.

Objective To investigate the effects of Qigong practice, Guan Yin Zi Zai Gong level 1, compared with a waiting list control group among office workers with chronic nonspecific low back pain (CNLBP). Methods A randomized controlled trial was conducted at offices in the Bangkok Metropolitan Region. Seventy-two office workers with CNLBP were screened for inclusion/exclusion criteria (age 20–40 years; sitting period more than 4 h per day) and were allocated randomly into two groups: the Qigong and waiting list groups ( n = 36 each). The participants in the Qigong group took a Qigong practice class (Guan Yin Zi Zai Gong level 1) for one hour per week for six weeks at their workstation. The participants were encouraged to conduct the Qigong exercise at home every day. The waiting list group received general advice regarding low back pain management. The primary outcomes were pain intensity, measured by the visual analog scale, and back functional disability, measured by the Roland and Morris Disability Questionnaire. The secondary outcomes were back range of motion, core stability performance index, heart rate, respiratory rate, the Srithanya Stress Scale (ST-5), and the global perceived effect (GPE) questionnaire. Results Compared to the baseline, participants in the Qigong group experienced significantly decreased pain intensity and back functional disability. No statistically significant difference in these parameters was found in the waiting list group. Comparing the two groups, Qigong exercise significantly improved pain intensity, back functional impairment, range of motion, core muscle strength, heart rate, respiratory rate, and mental status. The Qigong group also had a significantly higher global outcome satisfaction than the waiting list group. Conclusion Qigong practice is an option for treatment of CNLBP in office workers.

Objective: The aim was to compare the use of the four square step test (FSST) and the FSST with foam surface (FSST + foam) scores for discriminating between adults, faller older adults, and nonfaller older adults. Methods: Fifty-four participants (18 for each group) were assessed using the FSST and FSST + foam. The area under the curve (AUC) of receiver operating characteristic curve was calculated and used to compare the accuracy of the tests. Results: The FSST + foam was more accurate than FSST for discriminating between faller and nonfaller older adults (area under the curves were 0.765 and 0.725, respectively) and between nonfaller older adults and adults (area under the curves were 0.99 and 0.95, respectively). The cutoff score for discriminating between faller and nonfaller older adults was 11.21, with a sensitivity and specificity of 0.889 and 0.611, respectively. Conclusion: FSST + foam could be used as an alternative assessment for discriminating between adults, faller, and nonfaller older adults.

[Purpose] The potential health benefits of the Nintendo Wii balance board exercise have been widely investigated. However, no study has been conducted to examine the benefits of Wii exercise for overweight young adults. The aim of this study was to investigate the effect of exercise performed on a Nintendo Wii balance board on the balance and lower limb muscle strength in overweight young adults. [Subjects and Methods] Within-subject repeated measures analysis was used. Sixteen young adults (aged 21.87±1.13 years, body mass index 24.15 ± 0.50 kg/m(2)) were recruited. All subjects performed an exercise program on a Wii balance board for 8 weeks (30 min/session, twice a week for 8 weeks). A NeuroCom Balance Master and a hand-held dynamometer were used to measure balance performance and lower limb muscle strength. [Results] According to the comparison of pre- and post-intervention measurements, the Wii balance board exercise program significantly improved the limit of stability parameters. There was also a significant increase in strength of four lower-limb muscle groups: the hip flexor, knee flexor, ankle dorsiflexor and ankle plantarflexor. [Conclusion] These findings suggest that a Wii balance board exercise program can be used to improve the balance and lower limb muscle strength of overweight young adults.

Background and purpose Previous studies suggested that limits of stability (LOS) training with visual feedback using commercial equipment could be used to improve balance ability in individuals with stroke. However, this system is expensive. In this study, we created a new tool from inexpensive elements based on LOS training using visual feedback. The aim of this study was to investigate the effect of training using a new multidirectional reach tool on balance in individuals with stroke. Methods A single-blind randomized control trial was conducted. Individuals with stroke (n = 16; age range 38-72 years) were recruited. Participants in the experimental group were trained with the multidirectional reach training for 30 min and conventional physical therapy for 30 min per day, 3 days a week for 4 weeks. Participants in the control group received conventional physical therapy for 30 min per day, 3 days a week for 4 weeks. The outcomes were LOS, weight-bearing squat, and Fullerton Advanced Balance scale. All of the outcome measures were measured at pretraining, post-training, and 1 month follow-up. Results At post-training and 1-month follow-up, the participants in the experimental group had an improvement of dynamic balance than the control group. Furthermore, the activity assessment by Fullerton Advanced Balance scale was more improved at 1 month follow-up in the experimental group than control group. Conclusion The results of this study provide evidence that training using a new multidirectional reach tool is effective for improving balance in individuals with stroke.

Immobilized Spirulina mat was co-cultured with Pacific white shrimp (Penaeus vannamei) postlarvae for water quality control in a closed re-circulating system. During the culture period, the experimental Spirulina mat system showed total ammonia nitrogen and nitrate accumulation rates lower by 32.92 and 32.26 %, respectively, compared with the system without the mat. The water exchange rate in the system with the mat was comparatively reduced by 40 %. Moreover, survival rate, growth rate, and size (length) of the co-cultured shrimp larvae were greater than those of the control (P

The purpose of this study was to investigate the effects of exercise using a mung bean bag (MB) for balance ability. Thirty-nine healthy female young adults (aged 18-25 years with normal body mass index) were randomly assigned into three groups (n for each group = 13): control group, firm surface (FS) exercise group, and MB exercise group. The FS and MB groups were trained with static and dynamic balance exercises (20 minutes × 3 times/week × 6 weeks). Participants' balance abilities were measured using a Balance Master 4 times: at pre-training (baseline) and at the second, fourth, and sixth weeks post-training. Three tests were assessed: unilateral stance test, modified clinical test for sensory integrations on balance (mCTSIB), and limits of stability (LOS) test. The MB group significantly improved unilateral stance balance in both eyes-open and eyes-closed conditions, whereas the FS group improved only in the eyes-closed condition. No significant difference was found across groups in the mCTSIB parameters. Only the FS group significantly improved LOS parameters. These results suggest the MB exercise could be used to improve unilateral stance balance, but not the LOS or mCTSIB, in healthy young adults.

Schwann cell (SC) transplantation is a promising repair strategy after spinal cord injury (SCI); however, a large number of SCs do not survive following transplantation. Previous studies have shown that 17β-estradiol (E2) protects several cell types against cytotoxicity. Thus, this study evaluated the protective potential of E2 on SCs in vitro and investigated the effect of E2 on transplanted SC survival in a rat model of SCI. Primary SC cultures were found to robustly express estrogen receptors (ER) and incubation with E2 protected SCs against hydrogen peroxide-induced cell death. This protection was not inhibited by the ER antagonist ICI 182,780, suggesting that genomic signaling is not necessary for protection. In a subsequent experiment, cervical hemicontusion SCI was induced in male rats followed by sustained administration of E2 or placebo. Eight days after SCI, SCs were transplanted into the injury epicenter. E2 treatment significantly increased the number of surviving labeled transplanted SCs evaluated 7 days after transplantation. These data demonstrate that E2 protects SCs against oxidative stress and improves transplanted SC survival, which suggests that E2 administration may be an intervention of choice for enhancing survival of transplanted SCs after SCI.

[Purpose] The aim of the present study was to compare the effects of unstable support surfaces, i.e. foam pad, mung bean bag, and plastic bead bag, on postural stability disturbance. [Subjects and Methods] Twenty-two healthy young adults (11 male and 11 female; aged 21.09 ± 1.44 years; BMI 20.40 ± 1.40 kg/m(2)) participated in the study. The Balance Master™ was used to evaluate the limit of stability and the unilateral stance performance. Each participant was assessed while standing on the following surfaces: 1) a firm surface, 2) a foam pad, 3) a mung bean bag, and 4) a plastic bead bag. The order of surfaces was randomly assigned. [Results] The mung bean bag and plastic bead bag showed greater disturbances in limit of stability and unilateral stance than the foam pad. There was no significant difference in postural stability disturbance between the mung bean bag and plastic bead bag. [Conclusion] These results suggested that both the mung bean bag and plastic bead bag could be used as a low-cost tool for balance assessment instead of a foam pad in healthy young adults.