1. Volumetric evaluation of CT images of adrenal glands in primary aldosteronism
- Author
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Velema, M.S., Canu, L., Dekkers, T., Hermus, A.R.M.M., Timmers, H.J.L.M., Schultze Kool, L.J., Groenewoud, H., Sweep, F.C.G.J., Wilt, G.J. van der, Langenhuijsen, J.F., Lenders, J.W.M., Jacobs, C., Deinum, J., Public and occupational health, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, APH - Personalized Medicine, APH - Global Health, and ACS - Heart failure & arrhythmias
- Subjects
Prognostic factor ,Adrenal gland neoplasms ,Endocrinology, Diabetes and Metabolism ,Concordance ,Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] ,Adrenal Gland Neoplasm ,Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13] ,X-ray computed ,030209 endocrinology & metabolism ,Normal values ,CT-scanning ,Unilateral disease ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Primary aldosteronism ,Diagnosis ,Hyperaldosteronism ,medicine ,In patient ,Tomography ,business.industry ,Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16] ,medicine.disease ,Women's cancers Radboud Institute for Health Sciences [Radboudumc 17] ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,030220 oncology & carcinogenesis ,Nuclear medicine ,business ,Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] - Abstract
Contains fulltext : 244324.pdf (Publisher’s version ) (Open Access) OBJECTIVES: To investigate whether adrenal volumetry provides better agreement with adrenal vein sampling (AVS) than conventional CT for subtyping PA. Furthermore, we evaluated whether the size of this contralateral adrenal was a prognostic factor for clinical outcome after unilateral adrenalectomy. METHODS: We retrospectively analyzed volumes of both adrenal glands of the 180 CT-scans (88/180 with unilateral and 92/180 with bilateral disease) of the patients with PA included in the SPARTACUS trial of which 85 also had undergone an AVS. In addition, we examined CT-scans of 20 healthy individuals to compare adrenal volumes with published normal values. RESULTS: Adrenal volume was higher for the left than the right adrenal (mean and SD: 6.49 ± 2.77 ml versus 5.25 ± 1.87 ml for the right adrenal; p
- Published
- 2021