1. Recommendations on the management of pudendal nerve entrapment syndrome: A formalised expert consensus
- Author
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B. Rioult, Virginie Quistrebert, Michel Cosson, Claire Garreau, Marie-Aimée Perrouin-Verbe, Anne-Marie Leroi, Bertrand Quinio, Frédérique Mohy, Jean-Jacques Labat, Katleen Jottard, Pascale Picard, Rebecca Haddad, Christine Levêque, Roger Robert, Eric Bautrant, Guy Valancogne, Gérard Amarenco, Luc Bruyninx, Thibault Riant, Lara Quintas, Amandine Guinet-Lacoste, Xavier Deffieux, Thierry G. Vancaillie, Marc Beer Gabel, Stéphane Ploteau, Amélie Levesque, Centre hospitalier universitaire de Nantes (CHU Nantes), Pelvi-Perineal Surgery and Rehabilitation Department, Private Medical Centre 'l'Avancée-Clinique Axium', Aix en Provence, France., Tête d'or' Reeducation Centre, Lyon, France., Maurice Bensignor Multidisciplinary Pain Center, Centre Catherine de Sienne, Nantes, France., Neurogastroenterology and Pelvic Floor Unit, Sheba Medical Center, Tel Hashomer, Israel., Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Service de physiologie digestive, urinaire, respiratoire et de l'exercice [CHU Rouen], Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Department of Surgery, Brugmann Hospital, Brussels, Belgium., CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Department of Gynecology, Clinical Institute of Gynecology, Obstetrics, and Neonatology, Faculty of Medicine, Barcelona, Spain., CHU Clermont-Ferrand, Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), Hospices Civils de Lyon (HCL), Plate-forme Mouvement et handicap [Hôpital Henry Gabrielle - Lyon], Hôpital Henry Gabrielle [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Hôpital de la Cavale Blanche - CHRU Brest (CHU - BREST ), Department of Gynecologic Surgery, Jeanne de Flandre Hospital, CHU de Lille, Lille, France., AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and General Practitioner's Office, Le Bono, France.
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medicine.medical_specialty ,Consensus ,Pudendal nerve ,030232 urology & nephrology ,Primary care ,03 medical and health sciences ,0302 clinical medicine ,medicine ,[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] ,Effective treatment ,Humans ,Intensive care medicine ,Good practice ,ComputingMilieux_MISCELLANEOUS ,Pain Measurement ,Pudendal Neuralgia ,030219 obstetrics & reproductive medicine ,Pudendal Nerve Entrapment Syndrome ,Pulsed radiofrequency ,business.industry ,Expert consensus ,United States ,3. Good health ,Anesthesiology and Pain Medicine ,Homogeneous ,business - Abstract
BACKGROUND Since the development and publication of diagnostic criteria for pudendal nerve entrapment (PNE) syndrome in 2008, no comprehensive work has been published on the clinical knowledge in the management of this condition. The aim of this work was to develop recommendations on the diagnosis and the management of PNE. METHODS The methodology of this study was based on French High Authority for Health Method for the development of good practice and the literature review was based on the PRISMA method. The selected articles have all been evaluated according to the American Society of Interventional Pain Physicians assessment grid. RESULTS The results of the literature review and expert consensus are incorporated into 10 sections to describe diagnosis and management of PNE: (1) diagnosis of PNE, (2) patients advice and precautions, (3) drugs treatments, (4) physiotherapy, (5) transcutaneous electrostimulations (TENS), (6) psychotherapy, (7) injections, (8) surgery, (9) pulsed radiofrequency, and (10) Neuromodulation. The following major points should be noted: (i) the relevance of 4+1 Nantes criteria for diagnosis; (ii) the preference for initial monotherapy with tri-tetracyclics or gabapentinoids; (iii) the lack of effect of opiates, (iv) the likely relevance (pending more controlled studies) of physiotherapy, TENS and cognitive behavioural therapy; (v) the incertitudes (lack of data) regarding corticoid injections, (vi) surgery is a long term effective treatment and (vii) radiofrequency needs a longer follow-up to be currently proposed in this indication. CONCLUSION These recommendations should allow rational and homogeneous management of patients suffering from PNE. They should also allow to shorten the delays of management by directing the primary care. SIGNIFICANCE Pudendal nerve entrapment (PNE) has only been known for about 20 years and its management is heterogeneous from one practitioner to another. This work offers a synthesis of the literature and international experts' opinions on the diagnosis and management of PNE.
- Published
- 2021
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