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1. Italy's Rigoni di Asiago enters chocolate with Saveurs & Nature acquisition

Subjects: Chocolate industry -- International economic relations, Business, Food and beverage industries
Abstract: Byline: Simon Harvey Rigoni di Asiago, an Italy-based organic spreads producer, has snapped up chocolate maker Saveurs & Nature in France. The family-owned Italian firm said the deal will expand [...]
Published: 2022

2. Rigoni di Asiago Launches New Nocciolata Bianca Hazelnut Spread

Subjects: Cocoa, Company marketing practices, Business, Business, international
Abstract: Nocciolata Bianca is ethically sourced, organic and non-GMO, providing a natural hazelnut spread that doesn't compromise taste NEW YORK -- Rigoni di Asiago, a 96-year-old family-owned Italian foods brand, announced [...]
Published: 2019

3. Brandon Rigoni of Lincoln Industries Selected to Forbes Business Development Council

Subjects: Professional employees, Vice presidents (Organizations), Business, News, opinion and commentary
Abstract: Forbes Business Development Council Is an Invitation-Only Community for Senior-Level Sales and Business Development Executives LINCOLN, Neb., May 20, 2019 /PRNewswire-PRWeb/ -- Brandon Rigoni, Ph.D., Vice President of Business Development [...]
Published: 2019

4. Rigoni di Asiago Introduces New Nocciolata Bianca Hazelnut Spread

Subjects: Fruit spreads -- Product introduction, Food industry -- Product introduction, Cocoa, Gluten-free diet, Gluten, Food and beverage production/distribution software, Business, Business, international, Telecommunications industry
Abstract: Rigoni di Asiago reported the launch of its newest organic spread, Nocciolata Bianca. The all-hazelnut flavor joins Rigoni di Asiago's Nocciolata range of hazelnut and cocoa spreads, including its classic [...]
Published: 2019

5. Cervical cancer: from Hippocrates through Rigoni-Stern to zur Hausen

Author: Roberto Gasparini and Donatella Panatto
Subjects: Gynecology, Cervical cancer, medicine.medical_specialty, General Veterinary, General Immunology and Microbiology, business.industry, Papillomavirus Infections, Public Health, Environmental and Occupational Health, MEDLINE, Uterine Cervical Neoplasms, History, 20th Century, medicine.disease, History, 21st Century, Infectious Diseases, Stern, Molecular Medicine, Medicine, Humans, Female, business, History, Ancient
Published: 2009

6. THE PERCEPTION OF CORPORATE SOCIAL RESPONSIBILITY IN THE RELATIONSHIP OF CODESA AND TENANTS WITH THE SURROUNDING COMMUNITY/A PERCEPCAO DA RESPONSABILIDADE SOCIAL EMPRESARIAL NA RELACAO DA CODESA E ARRENDATARIAS COM A COMUNIDADE DO ENTORNO/LA PERCEPCION DE LA RESPONSABILIDAD SOCIAL EMPRESARIAL EN LA RELACION DE LA CODESA Y ARRENDATARIAS CON LA COMUNIDAD DEL ENTORNO

Author: Silva, Andreia Coutinho E., Rigoni, Adriana, Vasconcelos, Flavia Nico, and Lucas, Luiza Kister
Published: 2020
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7. 'Nuns, virgins, and spinsters'. Rigoni-Stern and cervical cancer revisited

Author: Malcolm Griffiths
Subjects: Adult, medicine.medical_specialty, Sexually Transmitted Diseases, Uterine Cervical Neoplasms, Risk Factors, Epidemiology, medicine, Humans, Female population, Sexual Abstinence, Gynecology, Cervical cancer, Vaginal Smears, Cervical cytology screening, business.industry, Obstetrics, Mortality rate, Incidence (epidemiology), Incidence, Obstetrics and Gynecology, Middle Aged, medicine.disease, Uterine Cervicitis, Religion, Sexual abstinence, Parity, Stern, Female, business
Abstract: The view that nuns have a very low risk of cervical cancer is questioned. The historical evidence for this view is reviewed, from the beginning of the eighteenth century to the present. An estimate of the actual mortality rate from cervical cancer suggests that risk of death from this neoplasm among nuns is little different from that among the general female population. It is recommended that nuns should not be excluded from cervical cytology screening. When symptoms which might suggest cervical cancer arise in such women, full gynaecological assessment is necessary.
Published: 1991

8. Rigoni plans to avoid Varig' merger

Subjects: Business, Business, international, News, opinion and commentary
Abstract: (From SABI (South American Business Information) - Gazeta Mercantil) Gilberto Rigoni, FRB[acute accent] board of directors chairman (Fundacao Ruben Berta, Varig[acute accent] controller) has announced he aims to resume the [...]
Published: 2003

9. Rigoni plans to avoid Varig' merger

Subjects: Business, Business, international
Abstract: Brazil, Jul 23, 2003 (Gazeta Mercantil/SABI via COMTEX) Gilberto Rigoni, FRB[acute accent] board of directors chairman (Fundacao Ruben Berta, Varig[acute accent] controller) has announced he aims to resume the alternative [...]
Published: 2003

10. Omaha World-Herald, Neb., Tom Shatel column: Tom Shatel: Missile accomplished for Captain Rigoni

Subjects: Business, Business, regional, General interest
Published: 2006

11. Rigoni 'the heart' of special teams

Subjects: Scholarships, Football teams, Business, Business, regional, General interest
Published: 2006

12. U. Nebraska: Rigoni diversifies skills, strives to up time on NU defense

Subjects: Business, Business, international, News, opinion and commentary
Abstract: (From University Wire) Byline: Joe Bonge Listen to Brandon Rigoni's philosophy on football, and it's easy to see what he's about. The senior free safety Lincoln Southeast High School graduate [...]
Published: 2006

13. INTERVIEW WITH LUCA RIGONI OF MEDIASET CHANNEL 5 OF ITALY

Subjects: Business, Business, international, News, opinion and commentary
Abstract: (From Regulatory Intelligence Data) QUESTION: Dr. Rice, today the Israeli prime minister and the Palestinian president will meet in Sharm el-Sheik. You just met them both. Are you optimistic in [...]
Published: 2005

14. The effect of air pollution on COVID‐19 severity in a sample of patients with multiple sclerosis

Author: Bergamaschi, Roberto, Ponzano, Marta, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Pisoni, Enrico, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria Pia, Gianmarco Abbadessa, Umberto Aguglia, Lia Allegorico, Rossi Beatrice Maria Allegri, Anastasia Alteno, Maria Pia Amato, Pietro Annovazzi, Carlo Antozzi, Lucia Appendino, Sebastiano Arena, Viola Baione, Roberto Balgera, Valeria Barcella, Damiano Baroncini, Caterina Barrilà, Mario A Battaglia, Alessandra Bellacosa, Gianmarco Bellucci, Roberto Bergamaschi, Valeria Bergamaschi, Daiana Bezzini, Beatrice Biolzi, Alvino Bisecco, Simona Bonavita, Giovanna Borriello, Chiara Bosa, Antonio Bosco, Francesca Bovis, Marco Bozzali, Laura Brambilla, Morra Vincenzo Brescia, Giampaolo Brichetto, Maria Buccafusca, Elisabetta Bucciantini, Sebastiano Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano Calabrese, Francesca Calabria, Francesca Caleri, Federico Camilli, Luisa Maria Caniatti, Roberto Cantello, Marco Capobianco, Ruggero Capra, Rocco Capuano, Luca Carmisciano, Patrizia Carta, Paola Cavalla, Maria Grazia Celani, Maria Cellerino, Raffaella Cerqua, Clara Chisari, Raffaella Clerici, Marinella Clerico, Eleonora Cocco, Gaia Cola, Giancarlo Comi, Paolo Confalonieri, Antonella Conte, Marta Zaffira Conti, Christian Cordano, Susanna Cordera, Cinzia Cordioli, Francesco Corea, Claudio Correale, Salvatore Cottone, Francesco Crescenzo, Erica Curti, Alessandro d'Ambrosio, Emanuele D'Amico, Maura Chiara Danni, Alessia d'Arma, Vincenzo Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Rossi, Nicola De Stefano, Cava Marco Della, Mario di Napoli, Alessia Di Sapio, Renato Docimo, Anna Dutto, Luana Evangelista, Salvatore Fanara, Diana Ferraro, Maria Teresa Ferrò, Massimo Filippi, Cristina Fioretti, Mario Fratta, Jessica Frau, Marzia Fronza, Roberto Furlan, Alberto Gajofatto, Antonio Gallo, Paolo Gallo, Claudio Gasperini, Anna Ghazaryan, Bruno Giometto, Francesca Gobbin, Flora Govone, Franco Granella, Erica Grange, Maria Grazia Grasso, Angelica Guareschi, Clara Guaschino, Simone Guerrieri, Donata Guidetti, Pietro Iaffaldano, Antonio Ianniello, Luigi Iasevoli, Paolo Immovilli, Daniele Imperiale, Maria Teresa Infante, Matilde Inglese, Rosa Iodice, Aniello Iovino, Giovanna Konrad, Doriana Landi, Roberta Lanzillo, Caterina Lapucci, Luigi Lavorgna, Maria Rita L'Episcopo, Serena Leva, Giuseppe Liberatore, Re Marianna Lo, Marco Longoni, Leonardo Lopiano, Lorena Lorefice, Matteo Lucchini, Giacomo Lus, Davide Maimone, Maria Malentacchi, Giulia Mallucci, Simona Malucchi, Chiara Rosa Mancinelli, Luca Mancinelli, Paolo Manganotti, Giorgia Teresa Maniscalco, Vittorio Mantero, Sabrina Marangoni, Damiano Marastoni, Girolama Alessandra Marfia, Fabiana Marinelli, Alessandro Marti, Boneschi Filippo Martinelli, Zoli Federco Masserano, Francesca Matta, Laura Mendozzi, Giuseppe Meucci, Silvia Miante, Giuseppina Miele, Eva Milano, Massimiliano Mirabella, Rosanna Missione, Marcello Moccia, Lucia Moiola, Sara Montepietra, Margherita MontiBragadin, Federico Montini, Roberta Motta, Raffaele Nardone, Carolina Gabri Nicoletti, Eduardo Nobile-Orazio, Agostino Nozzolillo, Marco Onofrj, Riccardo Orlandi, Anna Palmieri, Damiano Paolicelli, Livia Pasquali, Luisa Pastò, Francesco Patti, Elisabetta Pedrazzoli, Paola Perini, Ilaria Pesci, Maria Petracca, Alfredo Petrone, Carlo Piantadosi, Anna M Pietroboni, Federica Pinardi, Marta Ponzano, Emilio Portaccio, Mattia Pozzato, Carlo Pozzilli, Luca Prosperini, Alessandra Protti, Marta Radaelli, Paolo Ragonese, Sarah Rasia, Sabrina Realmuto, Anna Repice, Eleonora Rigoni, Maria Teresa Rilla, Francesca Rinaldi, Calogero Marcello Romano, Marco Ronzoni, Marco Rovaris, Francesca Ruscica, Loredana Sabattini, Giuseppe Salemi, Marco Salvetti, Lorenzo Saraceno, Alessia Sartori, Arianna Sartori, Elvira Sbragia, Cinzia Scandellari, Giuditta Ilaria Scarano, Valentina Scarano, Irene Schiavetti, Maria Sessa, Caterina Sgarito, Grazia Sibilia, Gabriele Siciliano, Alessio Signori, Elisabetta Signoriello, Leonardo Sinisi, Francesca Sireci, Patrizia Sola, Claudio Solaro, Maria Pia Sormani, Stefano Sotgiu, Maddalena Sparaco, Maria Laura Stromillo, Silvia Strumia, Emanuela Laura Susani, Giulietta Tabiadon, Francesco Teatini, Gioacchino Tedeschi, Valentina Tomassini, Simone Tonietti, Clerici Valentina Torri, Carla Tortorella, Simona Toscano, Rocco Totaro, Maria Trojano, Maria Trotta, Gabriella Turano, Monica Ulivelli, Manzo Valentino, Giovanna Vaula, Domizia Vecchio, Marco Vercellino, Elena Pinuccia Verrengia, Marika Vianello, Eleonora Virgilio, Francesca Vitetta, Stefano Vollaro, Mauro Zaffaroni, Mauro Zampolini, Ignazio Roberto Zarbo, Antonio Zito, Luigi Zuliani, Bergamaschi, R, Ponzano, M, Schiavetti, I, Carmisciano, L, Cordioli, C, Filippi, M, Radaelli, M, Immovilli, P, Capobianco, M, De Rossi, N, Brichetto, G, Cocco, E, Scandellari, C, Cavalla, P, Pesci, I, Zito, A, Confalonieri, P, Marfia, Ga, Perini, P, Inglese, M, Trojano, M, Brescia Morra, V, Pisoni, E, Tedeschi, G, Comi, G, Battaglia, Ma, Patti, F, Salvetti, M, Sormani, Mp, Abbadessa, Gianmarco, Umberto, Aguglia, Lia, Allegorico, Rossi Beatrice Maria Allegri, Anastasia, Alteno, Maria Pia Amato, Pietro, Annovazzi, Carlo, Antozzi, Lucia, Appendino, Sebastiano, Arena, Viola, Baione, Roberto, Balgera, Valeria, Barcella, Damiano, Baroncini, Caterina, Barrilà, Mario, A Battaglia, Alessandra, Bellacosa, Gianmarco, Bellucci, Roberto, Bergamaschi, Valeria, Bergamaschi, Daiana, Bezzini, Beatrice, Biolzi, Bisecco, Alvino, Bonavita, Simona, Giovanna, Borriello, Chiara, Bosa, Bosco, Antonio, Francesca, Bovi, Marco, Bozzali, Laura, Brambilla, Morra Vincenzo Brescia, Giampaolo, Brichetto, Maria, Buccafusca, Elisabetta, Bucciantini, Sebastiano, Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano, Calabrese, Francesca, Calabria, Francesca, Caleri, Federico, Camilli, Luisa Maria Caniatti, Roberto, Cantello, Marco, Capobianco, Ruggero, Capra, Capuano, Rocco, Luca, Carmisciano, Patrizia, Carta, Paola, Cavalla, Maria Grazia Celani, Maria, Cellerino, Raffaella, Cerqua, Clara, Chisari, Raffaella, Clerici, Marinella, Clerico, Eleonora, Cocco, Gaia, Cola, Giancarlo, Comi, Paolo, Confalonieri, Antonella, Conte, Marta Zaffira Conti, Christian, Cordano, Susanna, Cordera, Cinzia, Cordioli, Corea, Francesco, Claudio, Correale, Salvatore, Cottone, Francesco, Crescenzo, Erica, Curti, Alessandro, D'Ambrosio, Emanuele, D'Amico, Maura Chiara Danni, Alessia, D'Arma, Vincenzo, Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Rossi, Nicola De Stefano, Cava Marco Della, Mario di Napoli, Alessia Di Sapio, Docimo, Renato, Anna, Dutto, Luana, Evangelista, Salvatore, Fanara, Diana, Ferraro, Maria Teresa Ferrò, Massimo, Filippi, Cristina, Fioretti, Fratta, Mario, Jessica, Frau, Marzia, Fronza, Roberto, Furlan, Alberto, Gajofatto, Gallo, Antonio, Paolo, Gallo, Claudio, Gasperini, Anna, Ghazaryan, Bruno, Giometto, Francesca, Gobbin, Flora, Govone, Franco, Granella, Erica, Grange, Maria Grazia Grasso, Angelica, Guareschi, Clara, Guaschino, Simone, Guerrieri, Donata, Guidetti, Pietro, Iaffaldano, Antonio, Ianniello, Luigi, Iasevoli, Paolo, Immovilli, Daniele, Imperiale, Maria Teresa Infante, Matilde, Inglese, Rosa, Iodice, Aniello, Iovino, Giovanna, Konrad, Doriana, Landi, Roberta, Lanzillo, Caterina, Lapucci, Luigi, Lavorgna, Maria Rita L'Episcopo, Serena, Leva, Giuseppe, Liberatore, Re Marianna Lo, Marco, Longoni, Leonardo, Lopiano, Lorena, Lorefice, Matteo, Lucchini, Lus, Giacomo, Davide, Maimone, Maria, Malentacchi, Giulia, Mallucci, Simona, Malucchi, Chiara Rosa Mancinelli, Luca, Mancinelli, Paolo, Manganotti, Giorgia Teresa Maniscalco, Vittorio, Mantero, Sabrina, Marangoni, Damiano, Marastoni, Girolama Alessandra Marfia, Fabiana, Marinelli, Alessandro, Marti, Boneschi Filippo Martinelli, Zoli Federco Masserano, Francesca, Matta, Laura, Mendozzi, Giuseppe, Meucci, Silvia, Miante, Miele, Giuseppina, Eva, Milano, Massimiliano, Mirabella, Missione, Rosanna, Marcello, Moccia, Lucia, Moiola, Sara, Montepietra, Margherita, Montibragadin, Federico, Montini, Roberta, Motta, Raffaele, Nardone, Carolina Gabri Nicoletti, Eduardo, Nobile-Orazio, Agostino, Nozzolillo, Marco, Onofrj, Riccardo, Orlandi, Palmieri, Anna, Damiano, Paolicelli, Livia, Pasquali, Luisa, Pastò, Francesco, Patti, Elisabetta, Pedrazzoli, Paola, Perini, Ilaria, Pesci, Maria, Petracca, Alfredo, Petrone, Carlo, Piantadosi, Anna, M Pietroboni, Federica, Pinardi, Marta, Ponzano, Emilio, Portaccio, Mattia, Pozzato, Carlo, Pozzilli, Luca, Prosperini, Alessandra, Protti, Marta, Radaelli, Paolo, Ragonese, Sarah, Rasia, Sabrina, Realmuto, Anna, Repice, Eleonora, Rigoni, Maria Teresa Rilla, Francesca, Rinaldi, Calogero Marcello Romano, Marco, Ronzoni, Marco, Rovari, Francesca, Ruscica, Loredana, Sabattini, Giuseppe, Salemi, Marco, Salvetti, Lorenzo, Saraceno, Alessia, Sartori, Arianna, Sartori, Elvira, Sbragia, Cinzia, Scandellari, Giuditta Ilaria Scarano, Valentina, Scarano, Irene, Schiavetti, Maria, Sessa, Caterina, Sgarito, Grazia, Sibilia, Gabriele, Siciliano, Alessio, Signori, Signoriello, Elisabetta, Leonardo, Sinisi, Francesca, Sireci, Patrizia, Sola, Claudio, Solaro, Maria Pia Sormani, Stefano, Sotgiu, Sparaco, Maddalena, Maria Laura Stromillo, Silvia, Strumia, Emanuela Laura Susani, Giulietta, Tabiadon, Francesco, Teatini, Tedeschi, Gioacchino, Valentina, Tomassini, Simone, Tonietti, Clerici Valentina Torri, Carla, Tortorella, Simona, Toscano, Rocco, Totaro, Maria, Trojano, Trotta, Maria Consiglia, Gabriella, Turano, Monica, Ulivelli, Manzo, Valentino, Giovanna, Vaula, Domizia, Vecchio, Marco, Vercellino, Elena Pinuccia Verrengia, Marika, Vianello, Eleonora, Virgilio, Francesca, Vitetta, Stefano, Vollaro, Mauro, Zaffaroni, Mauro, Zampolini, Ignazio Roberto Zarbo, Zito, Guido Antonio, Bergamaschi, R., Ponzano, M., Schiavetti, I., Carmisciano, L., Cordioli, C., Filippi, M., Radaelli, M., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Cocco, E., Scandellari, C., Cavalla, P., Pesci, I., Zito, A., Confalonieri, P., Marfia, G. A., Perini, P., Inglese, M., Trojano, M., Brescia Morra, V., Pisoni, E., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Bergamaschi, Roberto, Ponzano, Marta, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Pisoni, Enrico, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria, Pia, Gianmarco, Abbadessa, Alvino, Bisecco, Simona, Bonavita, Antonio, Bosco, Rocco, Capuano, Francesco, Corea, Renato, Docimo, Mario, Fratta, Antonio, Gallo, Iodice, Rosa, Iovino, Aniello, Lanzillo, Roberta, Giacomo, Lu, Giuseppina, Miele, Rosanna, Missione, Moccia, Marcello, Anna, Palmieri, Elisabetta, Signoriello, Maddalena, Sparaco, Gioacchino, Tedeschi, Maria, Trotta, Antonio, Zito, and Luigi, Zuliani
Subjects: air pollution, coronavirus, multiple sclerosis, medicine.medical_specialty, Multivariate analysis, Coronavirus disease 2019 (COVID-19), Clinical Sciences, Air pollution, Sample (statistics), Neurodegenerative, Settore MED/26, medicine.disease_cause, Autoimmune Disease, law.invention, Sustainable Cities and Communities, Clinical Research, law, Humans, Medicine, Climate-Related Exposures and Conditions, Neurology & Neurosurgery, MuSC-19 study group, SARS-CoV-2, business.industry, Multiple sclerosis, Neurosciences, COVID-19, Retrospective cohort study, Original Articles, medicine.disease, Intensive care unit, Particulate Matter, Air Pollution, Multiple Sclerosis, Brain Disorders, coronaviru, Settore MED/26 - NEUROLOGIA, Good Health and Well Being, Neurology, multiple sclerosi, Emergency medicine, Original Article, Neurology (clinical), Ordered logit, business, Human
Abstract: Background and purpose Some studies have shown that air pollution, often assessed by thin particulate matter with diameter below 2.5 µg/m3 (PM2.5), may contribute to severe COVID‐19 courses, as well as play a role in the onset and evolution of multiple sclerosis (MS). However, the impact of air pollution on COVID‐19 has never been explored specifically amongst patients with MS (PwMS). This retrospective observational study aims to explore associations between PM2.5 and COVID‐19 severity amongst PwMS. Methods Data were retrieved from an Italian web‐based platform (MuSC‐19) which includes PwMS with COVID‐19. PM2.5 2016–2018 average concentrations were provided by the Copernicus Atmospheric Monitoring Service. Italian patients inserted in the platform from 15 January 2020 to 9 April 2021 with a COVID‐19 positive test were included. Ordered logistic regression models were used to study associations between PM2.5 and COVID‐19 severity. Results In all, 1087 patients, of whom 13% required hospitalization and 2% were admitted to an intensive care unit or died, were included. Based on the multivariate analysis, higher concentrations of PM2.5 increased the risk of worse COVID‐19 course (odds ratio 1.90; p = 0.009). Conclusions Even if several other factors explain the unfavourable course of COVID‐19 in PwMS, the role of air pollutants must be considered and further investigated., Air pollution, often assessed by particulate matter with diameter below 2.5 µg/m3, may contribute to severe COVID‐19 courses. 1087 patients were included, of whom 13% required hospitalization and 2% were admitted to an intensive care unit or died. Even if several other factors explain the unfavourable course of COVID‐19 in patients with multiple sclerosis, the role of air pollutants must be considered and further investigated.
Published: 2021
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15. Patient satisfaction with televisit in chronic neurologic disorders during Covid-19 pandemic

Author: Maria Teresa Rigoni, Federico Giopato, Matteo Fuccaro, Domenico Marco Bonifati, Marika Vianello, Irene Rosellini, Roberta Vitaliani, Anna Ghazaryan, Anna Palmieri, Francesco Pietrobon, Alberto Terrin, and Silvia Vittoria Guidoni
Subjects: medicine.medical_specialty, Patient satisfaction, Neurology, Coronavirus disease 2019 (COVID-19), business.industry, Pandemic, Emergency medicine, Medicine, Neurology (clinical), General Medicine, business, Article
Published: 2023
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16. Trust-formation processes in financial advisors: A structural equation model

Author: Caterina Cruciani, Ugo Rigoni, and Gloria Gardenal
Subjects: Finance, Financial advisory, MiFID2, Structural equation modelling, Trust, Trust-formation process, Settore SECS-P/11 - Economia degli Intermediari Finanziari, Economics and Econometrics, business.industry, media_common.quotation_subject, Financial instrument, Maturity (finance), Structural equation modeling, Fiduciary, Settore SECS-P/09 - Finanza Aziendale, Dictator game, Framing (social sciences), Service (economics), Norm (social), business, media_common
Abstract: This paper focuses on the investor-advisor relation, looking at financial advisory as a fiduciary service. Consistently with the economic literature on the Trust Game, we formalize trust between financial advisors and clients as driven by a combination of two traditional motives – a norm to trust and anticipated reciprocation. We use related literature and insights from the recently introduced European Markets in Financial Instruments Directive 2 (MiFID 2) to define an original survey to estimate a structural equation model of trust formation, where trust and its two main motives are described as latent variables. Besides this methodological contribution, we test the validity of the hypothesized structural relation and explore whether specific features of financial advisors are likely to lead to different trust-formation processes. We find that the professional framing (tied versus bank advisors) and the maturity (new entrants versus incumbents) of financial advisors do indeed support different trust-formation processes. We conclude by exploring how these processes may be differently affected by the new regulation and discussing implications for the financial advisory industry.
Published: 2021
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17. Sociomaterial Practices: Challenges in Developing a Virtual Business Community Platform in Agriculture

Author: Norberto Hoppen, Amarolinda da Costa Zanela Klein, and Eduardo Henrique Rigoni
Subjects: virtual business communities, mangle of practice, ICT adoption, agriculture, design science research, Business, HF5001-6182
Abstract: Virtual business communities (VBC) are virtual networks of people who share common interests and comprise online software platforms that enables the fast exchange of information, collaboration and business interactions. From 2011 to 2015, we developed a design science research to create a VBC platform for an agricultural cluster of flower growers in the South of Brazil. The goal of this platform was to help to structure and strengthen this cluster by bringing together buyers and sellers while fostering cooperation to boost cluster competitiveness and economic development in the region. However, a number of challenges surfaced during the process, which led to a failure in the VBC platform’s diffusion. We adopted a sociomaterial perspective based on the mangle of practice concept (Pickering, 1993) to investigate this failure, by analyzing the key challenges involved in developing a VBC platform in an agricultural context. As its main result, this paper reveals the mangling process during the design and application of the VBC platform and details the different instances of tuning between the participants and the technology. We observed resistance and factors that weakened cooperation and resulted in a lack of governance rules, which are key to the success of a VBC platform.
Published: 2017
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18. The use of micro-costing in an economic analysis of allogeneic HSCT in Brazil

Author: Fernanda Lutz Tolves, Claudia Caceres Astigarraga, Tatiana Schnorr Silva, Jaina da Costa Pereira, Caroline Nespolo de David, Gabriela Oliveira Zavaglia, M. P. Pereira, Jaqueline Driemeyer Correia Horvath, Dora Fraga Vargas, Carisi Anne Polanczyk, Thainá Dias Luft, Fabiano Barrionuevo, Fernanda Fetter Scherer, Ivaine Tais Sauthier Sartor, Luciane Nascimento Cruz, Liane Esteves Daudt, Bruna Stella Zanotto, Lisandra Della Costa Rigoni, Ana Paula Beck da Silva Etges, and Luciane Beatriz Kern
Subjects: medicine.medical_specialty, surgical procedures, operative, immune system diseases, business.industry, Allogeneic hsct, Micro costing, medicine, Economic analysis, Intensive care medicine, business, health care economics and organizations
Abstract: Objective: The objective of this study was to estimate treatment costs of Hematopoietic stem cell transplantation (HSCT) at a reference center in Brazil. Methods: The study population consisted of patients from the Unified Health System HSCT who underwent HSCT in southern Brazil between 2016 and 2019. Costs were measured using a micro-costing approach, based on Time-Driven Activity-based Costing (TDABC) adapted for economic studies in health and included the following steps: definition of the research question, structured data collection, and statistical analysis of results. Results: The total cost of HSCT was $155,110 ($92,794 – $249,146 USD). Matched unrelated donor HSCT was more expensive than matched related donor HSCT. The major cost factors involve post-ransplant complications, mainly the occurrence of infections. Concerning cost composition, exams and procedures represent the largest expense in HSCT (45%). Conclusion: These estimates could be applicable to further evaluations for HSCT cost-effectiveness and help healthcare decision-makers in middle-income countries
Published: 2021
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19. Test beam characterization of sensor prototypes for the CMS Barrel MIP Timing Detector

Author: P. Martinez del Arbol, A. Ghezzi, R. Carlin, Jennifer Ott, Matthew Joyce, V. Mechinsky, Geonhee Oh, C. Perez, Giulia Sorrentino, A. Benaglia, G. Pessina, I. Tlisova, Wolfgang Funk, O. Neogi, L. Gray, J. Varela, Erik Brücken, S. Ganjour, Balazs Ujvari, I. Dutta, Y. Zhang, R. Arcidiacono, P. Meridiani, G. Zhang, R. Paramatti, Francesco Pandolfi, Massimo Casarsa, G. Organtini, R. Bellan, Toyoko Orimoto, Jack King, Y. Onel, P. Debbins, M. W. Arenton, F. De Guio, Maria Spiropulu, Alexander Dermenev, E. Tiras, D. Del Re, Lautaro Narvaez, Christopher Madrid, D. Stuart, Si Xie, M. Wayne, D. Marlow, Tiehui Liu, Ryan Heller, Kamuran Dilsiz, M. Korjik, Christopher Rogan, Tanvi Wamorkar, Yuri Andreev, C. Rovelli, Fabio Cossutti, J. Wetzel, Nicolaus Kratochwil, Anton Karneyeu, Sebastian White, Amedeo Staiano, I. Dafinei, Mohammad Alhusseini, Badder Marzocchi, Gillian Kopp, H. Chen, Geum Bong Yu, Christopher Tully, U. Dosselli, D. Tlisov, Dave Winn, Wenbo Li, K. F. Di Petrillo, Richard J. Abbott, Bennett Marsh, Hasan Ogul, L. A. T. Bauerdick, I. Mandjavize, Mário Costa, Raffaella Tramontano, E. Hazen, A. Peck, Gintautas Tamulaitis, Simone Pigazzini, Martina Malberti, W. Sands, Michael Gardner, F. J.M. Geurts, J. C. Silva, Chang-Seong Moon, M. Benettoni, M. Paganoni, A. Mestvirishvili, M. Sahin, S. Ventura, S. Hedia, G. Dissertori, T. Tabarelli de Fatis, F. Guilloux, Maria Margherita Obertino, C. Royon, Jane Nachtman, J. Mao, Claudio Gotti, Marco Bellato, Roberto Mulargia, Nan Lu, Z. Ye, Enrico Robutti, Michele Gallinaro, Hyun-Chul Kim, C. McMahon, Francesca Maria Addesa, Yurii Maravin, Marco Toliman Lucchini, S. N. Gninenko, Slawek Tkaczyk, K. Kaadze, W. Lustermann, Valentina Sola, Fabio Monti, Stefan Gundacker, C. Fernandez Madrazo, F. Santanastasio, Sunil Dogra, Marco Ferrero, S. Li, R. Isocrate, Hee-Won Lee, S. Nargelas, Micah M. Murray, Abdollah Mohammadi, M. Campana, O. K. Köseyan, Nicola Redaelli, James Sheplock, Zehui Zhang, R. Bertoni, F. Golf, P. Checchia, Claudio Campagnari, Christopher Neu, Daniel Spitzbart, L. Zhang, A. G. Stahl Leiton, Ivan Ovtin, Joel Nathan Butler, R. Y. Zhu, Ulascan Sarica, Federico Siviero, E. Auffray, T. Isidori, M. Lazarovits, Diogo Bastos, Carlos Pena, Adolf Bornheim, J. S. Gonzalez, R. Jaramillo, Artur Apresyan, I. Schmidt, N. Minafra, Marta Tornago, D. Rigoni, M. Titov, R. Mazza, A. Abreu, S. Chidzik, S. Wu, Olmo Cerri, E. Di Marco, J. Trevor, Marcos Fernandez, Christina Wang, Shudhashil Bharthuar, Y. Musienko, Travis Anderson, J. S. H. Lee, R. Schmitz, M. Besancon, Ang Li, Nicolo Cartiglia, A. Ledovskoy, F. Caleb, F. Chlebana, Z. Flowers, Y. Tang, Benjamin Tannenwald, Brady R. Cox, Isabel Ojalvo, Olesia Radchenko, Paolo Carniti, A. Heering, M. Tosi, Livia Soffi, Indara Suarez, Xuejun Wang, Tahereh Sadat Niknejad, I. Vila, A.N. Kozyrev, Richard J. K. Taylor, Roberto Rossin, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CMS MTD, Abbott, R, Abreu, A, Addesa, F, Alhusseini, M, Anderson, T, Andreev, Y, Apresyan, A, Arcidiacono, R, Arenton, M, Auffray, E, Bastos, D, Bauerdick, L, Bellan, R, Bellato, M, Benaglia, A, Benettoni, M, Bertoni, R, Besancon, M, Bharthuar, S, Bornheim, A, Brucken, E, Butler, J, Campagnari, C, Campana, M, Carlin, R, Carniti, P, Cartiglia, N, Casarsa, M, Cerri, O, Checchia, P, Chen, H, Chidzik, S, Chlebana, F, Cossutti, F, Costa, M, Cox, B, Dafinei, I, de Guio, F, Debbins, P, del Re, D, Dermenev, A, Di Marco, E, Dilsiz, K, Di Petrillo, K, Dissertori, G, Dogra, S, Dosselli, U, Dutta, I, Caleb, F, Madrazo, C, Fernandez, M, Ferrero, M, Flowers, Z, Funk, W, Gallinaro, M, Ganjour, S, Gardner, M, Geurts, F, Ghezzi, A, Gninenko, S, Golf, F, Gonzalez, J, Gotti, C, Gray, L, Guilloux, F, Gundacker, S, Hazen, E, Hedia, S, Heering, A, Heller, R, Isidori, T, Isocrate, R, Jaramillo, R, Joyce, M, Kaadze, K, Karneyeu, A, Kim, H, King, J, Kopp, G, Korjik, M, Koseyan, O, Kozyrev, A, Kratochwil, N, Lazarovits, M, Ledovskoy, A, Lee, H, Lee, J, Li, A, Li, S, Li, W, Liu, T, Lu, N, Lucchini, M, Lustermann, W, Madrid, C, Malberti, M, Mandjavize, I, Mao, J, Maravin, Y, Marlow, D, Marsh, B, del Arbol, P, Marzocchi, B, Mazza, R, Mcmahon, C, Mechinsky, V, Meridiani, P, Mestvirishvili, A, Minafra, N, Mohammadi, A, Monti, F, Moon, C, Mulargia, R, Murray, M, Musienko, Y, Nachtman, J, Nargelas, S, Narvaez, L, Neogi, O, Neu, C, Niknejad, T, Obertino, M, Ogul, H, Oh, G, Ojalvo, I, Onel, Y, Organtini, G, Orimoto, T, Ott, J, Ovtin, I, Paganoni, M, Pandolfi, F, Paramatti, R, Peck, A, Perez, C, Pessina, G, Pena, C, Pigazzini, S, Radchenko, O, Redaelli, N, Rigoni, D, Robutti, E, Rogan, C, Rossin, R, Rovelli, C, Royon, C, Sahin, M, Sands, W, Santanastasio, F, Sarica, U, Schmidt, I, Schmitz, R, Sheplock, J, Silva, J, Siviero, F, Soffi, L, Sola, V, Sorrentino, G, Spiropulu, M, Spitzbart, D, Leiton, A, Staiano, A, Stuart, D, Suarez, I, de Fatis, T, Tamulaitis, G, Tang, Y, Tannenwald, B, Taylor, R, Tiras, E, Titov, M, Tkaczyk, S, Tlisov, D, Tlisova, I, Tornago, M, Tosi, M, Tramontano, R, Trevor, J, Tully, C, Ujvari, B, Varela, J, Ventura, S, Vila, I, Wamorkar, T, Wang, C, Wang, X, Wayne, M, Wetzel, J, White, S, Winn, D, Wu, S, Xie, S, Ye, Z, Yu, G, Zhang, G, Zhang, L, Zhang, Y, Zhang, Z, Zhu, R, Ministerio de Economía y Competitividad (España), European Organization for Nuclear Research, Fundação para a Ciência e a Tecnologia (Portugal), European Commission, Academy of Finland, Department of Energy (US), Helsinki Institute of Physics, Abbott, R., Abreu, A., Addesa, F., Alhusseini, M., Anderson, T., Andreev, Y., Apresyan, A., Arcidiacono, R., Arenton, M., Auffray, E., Bastos, D., Bauerdick, L. A. T., Bellan, R., Bellato, M., Benaglia, A., Benettoni, M., Bertoni, R., Besancon, M., Bharthuar, S., Bornheim, A., Brücken, E., Butler, J. N., Campagnari, C., Campana, M., Carlin, R., Carniti, P., Cartiglia, N., Casarsa, M., Cerri, O., Checchia, P., Chen, H., Chidzik, S., Chlebana, F., Cossutti, F., Costa, M., Cox, B., Dafinei, I., De Guio, F., Debbins, P., del Re, D., Dermenev, A., Di Marco, E., Dilsiz, K., Di Petrillo, K. F., Dissertori, G., Dogra, S., Dosselli, U., Dutta, I., Caleb, F., Fernandez Madrazo, C., Fernandez, M., Ferrero, M., Flowers, Z., Funk, W., Gallinaro, M., Ganjour, S., Gardner, M., Geurts, F., Ghezzi, A., Gninenko, S., Golf, F., Gonzalez, J., Gotti, C., Gray, L., Guilloux, F., Gundacker, S., Hazen, E., Hedia, S., Heering, A., Heller, R., Isidori, T., Isocrate, R., Jaramillo, R., Joyce, M., Kaadze, K., Karneyeu, A., Kim, H., King, J., Kopp, G., Korjik, M., Koseyan, O. K., Kozyrev, A., Kratochwil, N., Lazarovits, M., Ledovskoy, A., Lee, H., Lee, J., Li, A., Li, S., Li, W., Liu, T., Lu, N., Lucchini, M., Lustermann, W., Madrid, C., Malberti, M., Mandjavize, I., Mao, J., Maravin, Y., Marlow, D., Marsh, B., Martinez del Arbol, P., Marzocchi, B., Mazza, R., Mcmahon, C., Mechinsky, V., Meridiani, P., Mestvirishvili, A., Minafra, N., Mohammadi, A., Monti, F., Moon, C. S., Mulargia, R., Murray, M., Musienko, Y., Nachtman, J., Nargelas, S., Narvaez, L., Neogi, O., Neu, C., Niknejad, T., Obertino, M., Ogul, H., Oh, G., Ojalvo, I., Onel, Y., Organtini, G., Orimoto, T., Ott, J., Ovtin, I., Paganoni, M., Pandolfi, F., Paramatti, R., Peck, A., Perez, C., Pessina, G., Pena, C., Pigazzini, S., Radchenko, O., Redaelli, N., Rigoni, D., Robutti, E., Rogan, C., Rossin, R., Rovelli, C., Royon, C., Sahin, M. Ö., Sands, W., Santanastasio, F., Sarica, U., Schmidt, I., Schmitz, R., Sheplock, J., Silva, J. C., Siviero, F., Soffi, L., Sola, V., Sorrentino, G., Spiropulu, M., Spitzbart, D., Stahl Leiton, A. G., Staiano, A., Stuart, D., Suarez, I., Tabarelli de Fatis, T., Tamulaitis, G., Tang, Y., Tannenwald, B., Taylor, R., Tiras, E., Titov, M., Tkaczyk, S., Tlisov, D., Tlisova, I., Tornago, M., Tosi, M., Tramontano, R., Trevor, J., Tully, C. G., Ujvari, B., Varela, J., Ventura, S., Vila, I., Wamorkar, T., Wang, C., Wang, X., Wayne, M., Wetzel, J., White, S., Winn, D., Wu, S., Xie, S., Ye, Z., Yu, G. B., Zhang, G., Zhang, L., Zhang, Y., Zhang, Z., and Zhu (the CMS MTD Group), R.
Subjects: Physics - Instrumentation and Detectors, Scintillation and licht emission processes (solid, gas and liquid scintillators), APDS, Ga, CMOS imager, APDs, CCDs, CMOS imagers, EBCCDs, EMCCDs, Etc), G-APDs, Gas, Liquid scintillators), Photon detectors for UV, Scintillation and light emission processes (solid, Scintillators, Si-PMTs, Timing detectors, Visible and IR photons (solid-state) (PIN diodes, 7. Clean energy, 01 natural sciences, Lyso, 030218 nuclear medicine & medical imaging, law.invention, 0302 clinical medicine, law, Detectors and Experimental Techniques, physics.ins-det, time resolution, Instrumentation, Mathematical Physics, Event reconstruction, CMS, Detector, p: beam, Visible and IR photons (solid-state) (PIN diodes, APDS, Si-PMTs, G-APDx, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), Instrumentation and Detectors (physics.ins-det), PARTICLE PHYSICS, Visible and IR photons (solid-state) (PIN diode, performance, Si-PMT, Materials science, Bar (music), FOS: Physical sciences, Scintillator, 114 Physical sciences, EMCCD, 03 medical and health sciences, Silicon photomultiplier, Optics, 0103 physical sciences, photomultiplier: silicon, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], CCD, LARGE HADRON COLLIDER, 010308 nuclear & particles physics, business.industry, EBCCD, APD, G-APD, Timing detector, efficiency, scintillation counter: crystal, business, Beam (structure)
Abstract: CMS MTD collaboration: et al., The MIP Timing Detector will provide additional timing capabilities for detection of minimum ionizing particles (MIPs) at CMS during the High Luminosity LHC era, improving event reconstruction and pileup rejection. The central portion of the detector, the Barrel Timing Layer (BTL), will be instrumented with LYSO:Ce crystals and Silicon Photomultipliers (SiPMs) providing a time resolution of about 30 ps at the beginning of operation, and degrading to 50-60 ps at the end of the detector lifetime as a result of radiation damage. In this work, we present the results obtained using a 120 GeV proton beam at the Fermilab Test Beam Facility to measure the time resolution of unirradiated sensors. A proof-of-concept of the sensor layout proposed for the barrel region of the MTD, consisting of elongated crystal bars with dimensions of about 3×3×57 mm3 and with double-ended SiPM readout, is demonstrated. This design provides a robust time measurement independent of the impact point of the MIP along the crystal bar. We tested LYSO:Ce bars of different thickness (2, 3, 4 mm) with a geometry close to the reference design and coupled to SiPMs manufactured by Hamamatsu and Fondazione Bruno Kessler. The various aspects influencing the timing performance such as the crystal thickness, properties of the SiPMs (e.g. photon detection efficiency), and impact angle of the MIP are studied. A time resolution of about 28 ps is measured for MIPs crossing a 3 mm thick crystal bar, corresponding to a most probable value (MPV) of energy deposition of 2.6 MeV, and of 22 ps for the 4.2 MeV MPV energy deposition expected in the BTL, matching the detector performance target for unirradiated devices., We acknowledge the support provided to the MTD project by the following funding agencies: CERN; Academy of Finland, MEC, and HIP (Finland); CEA (France); NKFIH, OTKA-131991 (Hungary); INFN (Italy); NRF-2008-00460, 2018R1A6A1A06024970, 2020R1A2C1012322 (Republic of Korea); LAS (Lithuania); FCT (Portugal); MON, Rosatom, RAS, RFBR, and NRC KI (Russia); SEIDI, CPAN, PCTI, and FEDER (Spain); Swiss Funding Agencies (Switzerland); DOE and NSF (U.S.A.).
Published: 2021
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20. The upgrade of the control and data acquisition system of RFXMod2

Author: M. Moressa, G. Martini, Roberto Cavazzana, F. Molon, P. Barbato, M. Breda, Adriano Luchetta, Roberto Capobianco, Gabriele Manduchi, C. Taliercio, P. Simionato, N. Ferron, Enrico Zampiva, and A. Rigoni
Subjects: Control and Data Acquisition System, Computer science, Shell (computing), Electromagnetic Probes, RFXMod2, 01 natural sciences, 010305 fluids & plasmas, Data acquisition, Supervisory control, SCADA, Component (UML), 0103 physical sciences, General Materials Science, 010306 general physics, Field-programmable gate array, Civil and Structural Engineering, business.industry, Mechanical Engineering, RFX-Mod2, Plasma control, MARTe, Software quality, Upgrade, Nuclear Energy and Engineering, MDSPlus, Embedded system, business
Abstract: RFXMod2 is an upgrade of RFXMod that will use a modified shell and mechanical structure in order to enhance plasma proximity to the shell and therefore to improve plasma control. The Control and Data Acquisition System for most of the plant systems and diagnostics previously used in RFXMod will be refurbished, while others will be completely re-built. The most important component that will be completely renewed is the Electromagnetic Probes (EM) data acquisition system. In the former system data acquisition and real-time control were implemented using two different technologies, i.e. CompactPCI and VME, respectively. In RFXMod2 a new architecture based on XILINX Zynq FPGA will be used to carry out at the same time both high-speed data acquisition and resampled data streaming for active plasma control. Moreover, numeric integration of EM signals will be carried out by the same FPGA supervising data acquisition and streaming. The use of MDSplus will be retained in RFXMod2, while the MARTe framework used for real-time plasma control will be replaced by MARTe2, a new framework developed under strict software quality standards. Plant control in RFXMod2 will be supervised by WinCC-OA, replacing the previous FactoryLink SCADA systems. Older plant units such as vacuum control using outdated S5 PLCs will be replaced by new systems, using OPC communication with the supervisory system. Old CAMAC equipment in diagnostics will be replaced by CompactPCI technology, making it uniform with the rest of the diagnostic data acquisition systems. Finally, specialized devices implemented in CAMAC such as timing sequence generators will be replaced by custom devices implemented using the same Zynq FPGA technology of the EM data acquisition devices.
Published: 2021
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21. A New 'Denervation' Technique for Painful Arthritic Wrist

Author: Massimiliano Raggi, Luca Speri, and Massimo Rigoni
Subjects: musculoskeletal diseases, Denervation, 030222 orthopedics, medicine.medical_specialty, Wrist arthritis, business.industry, medicine.medical_treatment, Upper extremity joint, 030230 surgery, Wrist, Arthroplasty, Surgery, body regions, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, medicine, Nerve structure, Orthopedics and Sports Medicine, business, Surgical incision
Abstract: Wrist denervation is, by the way, one of the most performed and long-lasting surgical technique for wrist arthritis. Despite many progresses in upper extremity joint arthroplasty, wrist arthritis remains difficult to treat specially in young patients and heavy manual workers. The aim of this technical article is to describe a new outpatient's procedure in which applying pulsed radio frequency on nerve structure of the wrist could achieve similar clinical results of a wrist denervation without surgical incision.
Published: 2021
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22. Comparison between patient specific instrumentation and traditional technique in patients with total knee arthroplasty: An observational perspective study

Author: Martina Dalla Libera, Sergio Rigoni, Cesare Chemello, A. Ceccato, D. Pigatto, and Davide Conte
Subjects: musculoskeletal diseases, Knee function, 030222 orthopedics, medicine.medical_specialty, business.industry, Total knee arthroplasty, 030229 sport sciences, Thigh, Article, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Patient specific instrumentation, Gait analysis, Cohort, Physical therapy, Medicine, Orthopedics and Sports Medicine, In patient, Observational study, business
Abstract: Background Total knee arthroplasty surgery (TKA) using prenavigated Patient Specific Instruments (PSI) technique represents one of the most recent technological evolutions in development of prosthetic surgery. The aim of this study was to evaluate kinematic and functional recovery of patients operated with prenavigated PSI technique compared to those operated with traditional technique. Methods A cohort of 20 patients is divided in two groups; some are operated with traditional technique (with NexGen Knee system) and others with prenavigated PSI technique (with eMP Knee system) at Asiago Hospital. Limb circumferences are measured for edema evaluation and different evaluation forms are provided to patients: SF-36, KSS pre-surgery (T0), KSS 15 (T1) and 45 days after surgery (T2). Gait Analysis is performed 60 days post-surgery, after leaving crutches. Results The analysis of KSS and SF-36 evaluation forms shows a greater improvement in PSI Evolution group in terms of articulation (comparison between T0 and T1), knee function and early return to physical and social activities. Pain is lesser in NexGen group, in an earlier phase, but 45 days after surgery (T2) there are no significant differences between two groups. Perception of general state of health improves more and earlier in NexGen. In NexGen group edema evaluation had significant differences at the level of prosthetic leg, but not in knee and thigh. Overall: the walking pattern is more physiological in PSI Evolution group. Conclusions The present study highlighted the superiority of prenavigated PSI technique over traditional technique in recovering functionality of prosthetic knee and in restoring a more physiological path pattern.
Published: 2021
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23. Harm reduction in Europe: a framework for civil society-led monitoring

Author: Daan van der Gouwe, Rafaela de Quadros Rigoni, Tuukka Tammi, and Eberhard Schatz
Subjects: Civil society, Service (systems architecture), Substance-Related Disorders, 030508 substance abuse, Medicine (miscellaneous), Context (language use), Public Policy, 03 medical and health sciences, Civil society organisations, 0302 clinical medicine, Added value, Humans, 030212 general & internal medicine, Monitoring and evaluation, Harm reduction, business.industry, lcsh:Public aspects of medicine, Public Health, Environmental and Occupational Health, Methodology, Reproducibility of Results, lcsh:RA1-1270, Service provider, Public relations, Europe, Psychiatry and Mental health, Overdose prevention, Data quality, Business, 0305 other medical science
Abstract: Background Civil society organisations (CSOs) play a vital role in developing and implementing effective measures to reduce the harms of drug use. They are also fundamental actors to monitor and evaluate programmes and policies for improvement. While harm reduction services are subject to monitoring, and international and European indicators exist, a framework for civil society-led monitoring does not exist. This paper analyses the challenges and added values of developing such a framework for the European region. Methods Since 2018, a technical working group within Correlation-European Harm Reduction Network (C-EHRN) is developing and revising a monitoring framework, collecting—through National Focal Points—the experience of harm reduction service providers and service users in 34 European countries. The first round of data collection, in 2019, focused on hepatitis C, overdose prevention, new drug trends and civil society involvement in drug policies. Results Developing CSO-based harm reduction monitoring is a learning by doing process. Assuring reliability and national representativeness of the data was a central challenge. As most CSOs have little or no experience with monitoring and research and work in a local-based context, the monitoring approach and its indicators were adjusted to the local context in the second round, bringing more in-depth information and helping to improve results’ reliability. While this implied shifting from the initial focus on comparing responses at a national level, the change to collecting qualitative data reflecting local realities of service policies and delivery provides the foundations for a critical appraisal of these realities against European policy goals. This allowed to map discrepancies between official policies and their implementation, as well as identify gaps in and complement data collection from national-level agencies. Conclusions By focusing on local experiences regarding the delivery of global and European policy targets, C-EHRN monitoring uses the unique strengths of its CSOs network and generates information that complements the reporting by other monitoring agencies. Data reflecting the CSOs perspective is essential for optimising local planning of service provision and development of effective and respectful drug policies at national and European level. If data quality issues, as well as the sustainability of reporting, are adequately addressed, civil society monitoring can provide excellent added value for the monitoring of harm reduction in Europe.
Published: 2021

24. Primary central nervous system lymphoma mimicking autoimmune encephalitis: the role of autoantibody testing

Author: Matteo Gastaldi, Diego Franciotta, Patrizia Morbini, Paola Bini, Lisa Maria Farina, and Eleonora Rigoni
Subjects: Central Nervous System, Autoimmune encephalitis, medicine.medical_specialty, Neurology, Lymphoma, business.industry, Autoantibody, Primary central nervous system lymphoma, Hashimoto Disease, Dermatology, General Medicine, medicine.disease, Psychiatry and Mental health, Immunology, medicine, Encephalitis, Humans, Neurology (clinical), Neurosurgery, business, Autoantibodies, Neuroradiology
Published: 2020
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25. Deep vein thrombosis in SARS-CoV-2 pneumonia-affected patients within standard care units: Exploring a submerged portion of the iceberg

Author: Martina Montagnana, Nicola Martinelli, Anna Rigoni, Michele Milella, Anna Maria Azzini, Filippo Stefanoni, Francesca Pizzolo, Sergio De Marchi, Giacomo Marchi, Oliviero Olivieri, Simonetta Friso, Evelina Tacconelli, Domenico Girelli, Sara Pilotto, Giulia Sartori, Francesca Nalin, and Elisa Tinazzi
Subjects: 2019-20 coronavirus outbreak, medicine.medical_specialty, Deep vein, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, ComputingMethodologies_ARTIFICIALINTELLIGENCE, Article, Standard care, Deep vein thrombosis, medicine, ComputingMethodologies_COMPUTERGRAPHICS, business.industry, Hematology, medicine.disease, Thrombosis, Iceberg, Coronavirus disease 2019 (COVID-19), Pneumonia, Venous thrombosis, medicine.anatomical_structure, ComputingMethodologies_PATTERNRECOGNITION, Emergency medicine, business, Venous thromboembolism
Abstract: Graphical abstract Unlabelled Image, Highlights • An association between COVID-19 and venous thromboembolism (VTE) is now recognized. • The prevalence of VTE is high in COVID-19 patients hospitalized in standard care units. • The prevalence of VTE is high even though thromboprophylaxis and in patients estimated at low risk. • A high index of suspicion for VTE is crucial in patients with SARS-CoV-2 infection.
Published: 2020

26. Oral Bisoprolol for the treatment of non-resolving central serous chorioretinopathy: A case report

Author: G Napolitano, Enzo Maria Vingolo, V De Rosa, and Erika Rigoni
Subjects: medicine.medical_specialty, Serous fluid, endocrine system diseases, business.industry, medicine.drug_class, Bisoprolol, Internal medicine, medicine, business, Chronic central serous chorioretinopathy, Gastroenterology, Beta blocker, medicine.drug
Abstract: Purpose: To evaluate the effect of the beta blocker Bisoprolol in the treatment of chronic central serous chorioretinopathy (CSC).
Published: 2020
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27. Symptom Level Associations Between Attention-Deficit Hyperactivity Disorder and School Performance

Author: David C. Rettew, Laurin Kasehagen, Lynn Zanardi Blevins, and Megan Rigoni
Subjects: Male, Adolescent, behavioral disciplines and activities, Tourette syndrome, Article, Odds, Handwriting, Individualized Education Program, Academic Performance, mental disorders, medicine, Humans, Attention deficit hyperactivity disorder, 0501 psychology and cognitive sciences, Child, Association (psychology), Psychiatric Status Rating Scales, business.industry, 05 social sciences, 050301 education, medicine.disease, Health Surveys, Confidence interval, Cross-Sectional Studies, School performance, Attention Deficit Disorder with Hyperactivity, Pediatrics, Perinatology and Child Health, Regression Analysis, Female, business, 0503 education, 050104 developmental & child psychology, Clinical psychology
Abstract: Attention-deficit hyperactivity disorder (ADHD) is associated with reduced school performance. To determine which ADHD symptoms and subtypes have the strongest association, we used type and frequency of symptoms on the 2014 National Survey of the Diagnosis and Treatment of ADHD and Tourette Syndrome (NS-DATA) to create symptom scores for inattention and hyperactivity-impulsivity and define subtypes (ADHD-Inattentive [ADHD-I], ADHD-Hyperactive-Impulsive, ADHD-Combined [ADHD-C]). Regression methods were used to examine associations between symptoms and subtype and a composite measure of school performance. Children with ADHD-C and ADHD-I had higher adjusted odds of having reduced overall school performance (ADHD-C = 5.8, 95% confidence interval [CI] = 3.1-10.9; ADHD-I = 5.5, 95% CI = 3.1-10.1) compared with children without ADHD. All inattentive symptoms were significantly related to reduced school performance in reading, writing, and handwriting, while 6 of 9 symptoms were significantly associated in mathematics. Children with ADHD-I were significantly more likely than children with other ADHD subtypes to receive a school-based Individualized Education Program or 504 Plan. ADHD-I symptoms may be broadly linked to reduced school performance.
Published: 2020
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28. Prognostic factors for VTE and bleeding in hospitalized medical patients: a systematic review and meta-analysis

Author: Rami Z. Morsi, Samer G. Karam, Holger J. Schünemann, Andrea Darzi, Lawrence Mbuagbaw, Frederick A. Spencer, Elie A. Akl, Alfonso Iorio, Federico Germini, Mary Cushman, Michael K. Gould, Marta Rigoni, Neil A. Zakai, Arnav Agarwal, Itziar Etxeandia-Ikobaltzeta, Alex C. Spyropoulos, Rana Charide, Scott C. Woller, and Michael B. Streiff
Subjects: Adult, Male, medicine.medical_specialty, Anemia, medicine.medical_treatment, Immunology, Hemorrhage, Comorbidity, 030204 cardiovascular system & hematology, Thrombophilia, Malignancy, Biochemistry, Thrombosis and Hemostasis, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Humans, cardiovascular diseases, 030212 general & internal medicine, Aged, Aged, 80 and over, Inpatients, Thrombocytosis, business.industry, Age Factors, Venous Thromboembolism, Cell Biology, Hematology, Length of Stay, Middle Aged, Prognosis, medicine.disease, Hospitalization, Systematic review, Meta-analysis, Female, business, Central venous catheter
Abstract: There may be many predictors of venous thromboembolism (VTE) and bleeding in hospitalized medical patients, but until now, systematic reviews and assessments of the certainty of the evidence have not been published. We conducted a systematic review to identify prognostic factors for VTE and bleeding in hospitalized medical patients and searched Medline and EMBASE from inception through May 2018. We considered studies that identified potential prognostic factors for VTE and bleeding in hospitalized adult medical patients. Reviewers extracted data in duplicate and independently and assessed the certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach. Of 69 410 citations, we included 17 studies in our analysis: 14 that reported on VTE, and 3 that reported on bleeding. For VTE, moderate-certainty evidence showed a probable association with older age; elevated C-reactive protein (CRP), D-dimer, and fibrinogen levels; tachycardia; thrombocytosis; leukocytosis; fever; leg edema; lower Barthel Index (BI) score; immobility; paresis; previous history of VTE; thrombophilia; malignancy; critical illness; and infections. For bleeding, moderate-certainty evidence showed a probable association with older age, sex, anemia, obesity, low hemoglobin, gastroduodenal ulcers, rehospitalization, critical illness, thrombocytopenia, blood dyscrasias, hepatic disease, renal failure, antithrombotic medication, and presence of a central venous catheter. Elevated CRP, a lower BI, a history of malignancy, and elevated heart rate are not included in most VTE risk assessment models. This study informs risk prediction in the management of hospitalized medical patients for VTE and bleeding; it also informs guidelines for VTE prevention and future research.
Published: 2020
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29. Market discipline on bank bond issues through the lens of a new forward‐looking measure of loan quality

Author: Siva Nathan, Ugo Rigoni, Elisa Cavezzali, and Giorgia Simion
Subjects: 502009 Corporate finance, bank loan quality, banks, market discipline, sovereign debt crisis, unsecured bond issues, Settore SECS-P/11 - Economia degli Intermediari Finanziari, media_common.quotation_subject, 502004 Banking management, Financial system, Market discipline, Through-the-lens metering, 502009 Finanzwirtschaft, Accounting, 0502 economics and business, 502004 Bankbetriebslehre, Quality (business), media_common, 040101 forestry, Measure (data warehouse), 050208 finance, Bond, Specific-information, 05 social sciences, 04 agricultural and veterinary sciences, Risk perception, Loan, 0401 agriculture, forestry, and fisheries, Business, General Economics, Econometrics and Finance
Abstract: Using unsecured bond spreads over the 2007 to mid‐2014 period, we test investors’ ability to price bank loan risk. We use a new measure of loan risk that incorporates forward‐looking information embedded in ratings assigned by external rating agencies to bank loan portfolios. Only Italian banks are required to systematically disclose this specific information. We find that investors do price forward‐looking information inherent in bank loan portfolios. This finding reflects the increase in risk perception following the sovereign debt crisis, which had the strongest effects on peripheral countries, with tensions in the lending market. Overall, these results suggest that our new forward‐looking measure provides an additional channel through which market discipline can operate.
Published: 2020
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30. Statistical facts about cancers on which Doctor Rigoni-Stern based his contribution to the Surgeons' Subgroup of the IV Congress of the Italian Scientists on 23 September 1842. (translation)

Author: Biancaw De Stavola
Subjects: Statistics and Probability, Male, Pediatrics, medicine.medical_specialty, Epidemiology, business.industry, Breast Neoplasms, History, 19th Century, Stern, Italy, Family medicine, Neoplasms, Uterine Neoplasms, Medicine, Humans, Female, business
Published: 1987

31. SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study

Author: Maria Pia Sormani, Irene Schiavetti, Doriana Landi, Luca Carmisciano, Nicola De Rossi, Cinzia Cordioli, Lucia Moiola, Marta Radaelli, Paolo Immovilli, Marco Capobianco, Vincenzo Brescia Morra, Maria Trojano, Gioacchino Tedeschi, Giancarlo Comi, Mario Alberto Battaglia, Francesco Patti, Yara Dadalti Fragoso, Sedat Sen, Aksel Siva, Roberto Furlan, Marco Salvetti, Gianmarco Abbadessa, Umberto Aguglia, Lia Allegorico, Rossi Beatrice Maria Allegri, Maria Pia Amato, Pietro Annovazzi, Carlo Antozzi, Lucia Appendino, Sebastiano Arena, Viola Baione, Roberto Balgera, Valeria Barcella, Damiano Baroncini, Caterina Barrilà, Mario A. Battaglia, Alessandra Bellacosa, Gianmarco Bellucci, Roberto Bergamaschi, Valeria Bergamaschi, Daiana Bezzini, Beatrice Biolzi, Alvino Bisecco, Simona Bonavita, Giovanna Borriello, Chiara Bosa, Antonio Bosco, Francesca Bovis, Marco Bozzali, Laura Brambilla, Morra Vincenzo Brescia, Giampaolo Brichetto, Maria Buccafusca, Elisabetta Bucciantini, Sebastiano Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano Calabrese, Francesca Calabria, Francesca Caleri, Federico Camilli, Luisa Maria Caniatti, Roberto Cantello, Ruggero Capra, Rocco Capuano, Patrizia Carta, Paola Cavalla, Maria Grazia Celani, Maria Cellerino, Raffaella Cerqua, Clara Chisari, Raffaella Clerici, Marinella Clerico, Eleonora Cocco, Gaia Cola, Paolo Confalonieri, Antonella Conte, Marta Zaffira Conti, Christian Cordano, Susanna Cordera, Francesco Corea, Claudio Correale, Salvatore Cottone, Francesco Crescenzo, Erica Curti, Alessandro d’Ambrosio, Emanuele D’Amico, Maura Chiara Danni, Alessia d’Arma, Vincenzo Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Stefano, Marco Della Cava, Mario di Napoli, Alessia Di Sapio, Renato Docimo, Anna Dutto, Luana Evangelista, Salvatore Fanara, Diana Ferraro, Maria Teresa Ferrò, Massimo Filippi, Cristina Fioretti, Mario Fratta, Jessica Frau, Marzia Fronza, Alberto Gajofatto, Antonio Gallo, Paolo Gallo, Claudio Gasperini, Anna Ghazaryan, Bruno Giometto, Francesca Gobbin, Flora Govone, Franco Granella, Erica Grange, Maria Grazia Grasso, Angelica Guareschi, Clara Guaschino, Simone Guerrieri, Donata Guidetti, Pietro Iaffaldano, Antonio Ianniello, Luigi Iasevoli, Daniele Imperiale, Maria Teresa Infante, Matilde Inglese, Rosa Iodice, Aniello Iovino, Giovanna Konrad, Roberta Lanzillo, Caterina Lapucci, Luigi Lavorgna, Rita L’Episcopo Maria, Serena Leva, Giuseppe Liberatore, Marianna Lo Re, Marco Longoni, Leonardo Lopiano, Lorena Lorefice, Matteo Lucchini, Giacomo Lus, Davide Maimone, Maria Malentacchi, Giulia Mallucci, Simona Malucchi, Chiara Rosa Mancinelli, Luca Mancinelli, Paolo Manganotti, Teresa Giorgia Maniscalco, Vittorio Mantero, Sabrina Marangoni, Damiano Marastoni, Alessandra Girolama Marfia, Fabiana Marinelli, Alessandro Marti, Filippo Martinelli Boneschi, Federco Masserano Zoli, Francesca Matta, Laura Mendozzi, Giuseppe Meucci, Silvia Miante, Giuseppina Miele, Eva Milano, Massimiliano Mirabella, Rosanna Missione, Marcello Moccia, Sara Montepietra, Margherita Monti Bragadin, Federico Montini, Roberta Motta, Raffaele Nardone, Carolina Gabri Nicoletti, Eduardo Nobile-Orazio, Agostino Nozzolillo, Marco Onofrj, Riccardo Orlandi, Anna Palmieri, Damiano Paolicelli, Livia Pasquali, Luisa Pastò, Elisabetta Pedrazzoli, Paola Perini, Ilaria Pesci, Maria Petracca, Alfredo Petrone, Carlo Piantadosi, Anna M. Pietroboni, Federica Pinardi, Marta Ponzano, Emilio Portaccio, Mattia Pozzato, Carlo Pozzilli, Luca Prosperini, Alessandra Protti, Paolo Ragonese, Sarah Rasia, Sabrina Realmuto, Anna Repice, Eleonora Rigoni, Maria Teresa Rilla, Francesca Rinaldi, Calogero Marcello Romano, Marco Ronzoni, Marco Rovaris, Francesca Ruscica, Loredana Sabattini, Giuseppe Salemi, Lorenzo Saraceno, Alessia Sartori, Arianna Sartori, Elvira Sbragia, Cinzia Scandellari, Ilaria Scarano Giuditta, Valentina Scarano, Valentina Schillaci, Maria Sessa, Caterina Sgarito, Grazia Sibilia, Gabriele Siciliano, Alessio Signori, Elisabetta Signoriello, Leonardo Sinisi, Francesca Sireci, Patrizia Sola, Claudio Solaro, Stefano Sotgiu, Maddalena Sparaco, Maria Laura Stromillo, Silvia Strumia, Laura Emanuela Susani, Giulietta Tabiadon, Francesco Teatini, Valentina Tomassini, Simone Tonietti, Clerici Valentina Torri, Carla Tortorella, Simona Toscano, Rocco Totaro, Maria Trotta, Gabriella Turano, Monica Ulivelli, Manzo Valentino, Giovanna Vaula, Domizia Vecchio, Marco Vercellino, Elena Pinuccia Verrengia, Marika Vianello, Eleonora Virgilio, Francesca Vitetta, Stefano Vollaro, Mauro Zaffaroni, Mauro Zampolini, Ignazio Roberto Zarbo, Antonio Zito, Luigi Zuliani, Sormani, M. P., Schiavetti, I., Landi, D., Carmisciano, L., De Rossi, N., Cordioli, C., Moiola, L., Radaelli, M., Immovilli, P., Capobianco, M., Brescia Morra, V., Trojano, M., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Fragoso, Y. D., Sen, S., Siva, A., Furlan, R., Salvetti, M., Bisecco, Alvino, Pia Sormani, Maria, Schiavetti, Irene, Landi, Doriana, Carmisciano, Luca, De Rossi, Nicola, Cordioli, Cinzia, Moiola, Lucia, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, Brescia Morra, Vincenzo, Trojano, Maria, Tedeschi, Gioacchino, Comi, Giancarlo, Alberto Battaglia, Mario, Patti, Francesco, Dadalti Fragoso, Yara, Sen, Sedat, Siva, Aksel, Furlan, Roberto, Salvetti, Marco, Study Group Gianmarco Abbadessa, MuSC-19, Aguglia, Umberto, Allegorico, Lia, Beatrice Maria Allegri, Rossi, Pia Amato, Maria, Annovazzi, Pietro, Antozzi, Carlo, Appendino, Lucia, Arena, Sebastiano, Baione, Viola, Balgera, Roberto, Barcella, Valeria, Baroncini, Damiano, Barrilà, Caterina, A Battaglia, Mario, Bellacosa, Alessandra, Bellucci, Gianmarco, Bergamaschi, Roberto, Bergamaschi, Valeria, Bezzini, Daiana, Biolzi, Beatrice, Bonavita, Simona, Borriello, Giovanna, Bosa, Chiara, Bosco, Antonio, Bovis, Francesca, Bozzali, Marco, Brambilla, Laura, Vincenzo Brescia, Morra, Brichetto, Giampaolo, Buccafusca, Maria, Bucciantini, Elisabetta, Bucello, Sebastiano, Chiara Buscarinu, Maria, Paola Cabboi, Maria, Calabrese, Massimiliano, Calabria, Francesca, Caleri, Francesca, Camilli, Federico, Maria Caniatti, Luisa, Cantello, Roberto, Capra, Ruggero, Capuano, Rocco, Carta, Patrizia, Cavalla, Paola, Grazia Celani, Maria, Cellerino, Maria, Cerqua, Raffaella, Chisari, Clara, Clerici, Raffaella, Clerico, Marinella, Cocco, Eleonora, Cola, Gaia, Confalonieri, Paolo, Conte, Antonella, Zaffira Conti, Marta, Cordano, Christian, Cordera, Susanna, Corea, Francesco, Correale, Claudio, Cottone, Salvatore, Crescenzo, Francesco, Curti, Erica, D'Ambrosio, Alessandro, D'Amico, Emanuele, Chiara Danni, Maura, D'Arma, Alessia, Dattola, Vincenzo, de Biase, Stefano, De Luca, Giovanna, Federica De Mercanti, Stefania, De Mitri, Paolo, De Stefano, Nicola, Della Cava, Marco, di Napoli, Mario, Di Sapio, Alessia, Docimo, Renato, Dutto, Anna, Evangelista, Luana, Fanara, Salvatore, Ferraro, Diana, Teresa Ferrò, Maria, Filippi, Massimo, Fioretti, Cristina, Fratta, Mario, Frau, Jessica, Fronza, Marzia, Gajofatto, Alberto, Gallo, Antonio, Gallo, Paolo, Gasperini, Claudio, Ghazaryan, Anna, Giometto, Bruno, Gobbin, Francesca, Govone, Flora, Granella, Franco, Grange, Erica, Grazia Grasso, Maria, Guareschi, Angelica, Guaschino, Clara, Guerrieri, Simone, Guidetti, Donata, Iaffaldano, Pietro, Ianniello, Antonio, Iasevoli, Luigi, Imperiale, Daniele, Teresa Infante, Maria, Inglese, Matilde, Iodice, Rosa, Iovino, Aniello, Konrad, Giovanna, Lanzillo, Roberta, Lapucci, Caterina, Lavorgna, Luigi, L'Episcopo Maria, Rita, Leva, Serena, Liberatore, Giuseppe, Lo Re, Marianna, Longoni, Marco, Lopiano, Leonardo, Lorefice, Lorena, Lucchini, Matteo, Lus, Giacomo, Maimone, Davide, Malentacchi, Maria, Mallucci, Giulia, Malucchi, Simona, Rosa Mancinelli, Chiara, Mancinelli, Luca, Manganotti, Paolo, Giorgia Maniscalco, Teresa, Mantero, Vittorio, Marangoni, Sabrina, Marastoni, Damiano, Girolama Marfia, Alessandra, Marinelli, Fabiana, Marti, Alessandro, Martinelli Boneschi, Filippo, Masserano Zoli, Federco, Matta, Francesca, Mendozzi, Laura, Meucci, Giuseppe, Miante, Silvia, Miele, Giuseppina, Milano, Eva, Mirabella, Massimiliano, Missione, Rosanna, Moccia, Marcello, Montepietra, Sara, Monti Bragadin, Margherita, Montini, Federico, Motta, Roberta, Nardone, Raffaele, Gabri Nicoletti, Carolina, Nobile-Orazio, Eduardo, Nozzolillo, Agostino, Onofrj, Marco, Orlandi, Riccardo, Palmieri, Anna, Paolicelli, Damiano, Pasquali, Livia, Pastò, Luisa, Pedrazzoli, Elisabetta, Perini, Paola, Pesci, Ilaria, Petracca, Maria, Petrone, Alfredo, Piantadosi, Carlo, M Pietroboni, Anna, Pinardi, Federica, Ponzano, Marta, Portaccio, Emilio, Pozzato, Mattia, Pozzilli, Carlo, Prosperini, Luca, Protti, Alessandra, Ragonese, Paolo, Rasia, Sarah, Realmuto, Sabrina, Repice, Anna, Rigoni, Eleonora, Teresa Rilla, Maria, Rinaldi, Francesca, Marcello Romano, Calogero, Ronzoni, Marco, Rovaris, Marco, Ruscica, Francesca, Sabattini, Loredana, Salemi, Giuseppe, Saraceno, Lorenzo, Sartori, Alessia, Sartori, Arianna, Sbragia, Elvira, Scandellari, Cinzia, Scarano Giuditta, Ilaria, Scarano, Valentina, Schillaci, Valentina, Sessa, Maria, Sgarito, Caterina, Sibilia, Grazia, Siciliano, Gabriele, Signori, Alessio, Signoriello, Elisabetta, Sinisi, Leonardo, Sireci, Francesca, Sola, Patrizia, Solaro, Claudio, Sotgiu, Stefano, Sparaco, Maddalena, Laura Stromillo, Maria, Strumia, Silvia, Emanuela Susani, Laura, Tabiadon, Giulietta, Teatini, Francesco, Tomassini, Valentina, Tonietti, Simone, Valentina Torri, Clerici, Tortorella, Carla, Toscano, Simona, Totaro, Rocco, Trotta, Maria, Turano, Gabriella, Ulivelli, Monica, Valentino, Manzo, Vaula, Giovanna, Vecchio, Domizia, Vercellino, Marco, Pinuccia Verrengia, Elena, Vianello, Marika, Virgilio, Eleonora, Vitetta, Francesca, Vollaro, Stefano, Zaffaroni, Mauro, Zampolini, Mauro, Roberto Zarbo, Ignazio, Zito, Antonio, Zuliani, Luigi, Abbadessa, Gianmarco, Trotta, Maria Consiglia, and Zito, Guido Antonio
Subjects: 0301 basic medicine, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), immunosuppressive therapie, coronavirus, Settore MED/26, medicine.disease_cause, Antibodies, Viral, immunosuppressive therapies, Antibodies, Serology, Cohort Studies, Multiple sclerosis, 03 medical and health sciences, 0302 clinical medicine, Seroepidemiologic Studies, Pandemic, Medicine, Humans, Multiple sclerosi, Viral, Coronavirus, business.industry, immunomodulatory therapie, immunomodulatory therapies, COVID-19, medicine.disease, Virology, coronaviru, Settore MED/26 - NEUROLOGIA, Sars-COV-2, 030104 developmental biology, Neurology, Neurology (clinical), business, SARS-CoV-2, Multiple Sclerosis, 030217 neurology & neurosurgery, Cohort study
Abstract: Background: The MuSC-19 project is an Italian cohort study open to international partners that collects data on multiple sclerosis (MS) patients with COVID-19. During the second wave of the pandemic, serological tests became routinely available. Objective: To evaluate the seroprevalence of anti-SARS-CoV-2 antibodies according to the use of disease-modifying therapy (DMT) in a subset of patients included in the MuSC-19 data set who had undergone a serological test. Methods: We evaluated the association between positive serological test results and time elapsed since infection onset, age, sex, Expanded Disability Status Scale score, comorbidities and DMT exposure using a multivariable logistic model. Results: Data were collected from 423 patients (345 from Italy, 61 from Turkey and 17 from Brazil) with a serological test performed during follow-up. Overall, 325 out of 423 tested patients (76.8%) had a positive serological test. At multivariate analysis, therapy with anti-CD20 was significantly associated with a reduced probability of developing antibodies after COVID-19 (odds ratio (OR) = 0.20, p = 0.002). Conclusion: Patients with MS maintain the capacity to develop humoral immune response against SARS-COV-2, although to a lesser extent when treated with anti-CD20 drugs. Overall, our results are reassuring with respect to the possibility to achieve sufficient immunization with vaccination.
Published: 2021

32. COVID-19 Severity in Multiple Sclerosis: Putting Data Into Context

Author: Maria Pia Sormani, Irene Schiavetti, Luca Carmisciano, Cinzia Cordioli, Massimo Filippi, Marta Radaelli, Paolo Immovilli, Marco Capobianco, Nicola De Rossi, Giampaolo Brichetto, Eleonora Cocco, Cinzia Scandellari, Paola Cavalla, Ilaria Pesci, Antonio Zito, Paolo Confalonieri, Girolama Alessandra Marfia, Paola Perini, Matilde Inglese, Maria Trojano, Vincenzo Brescia Morra, Gioacchino Tedeschi, Giancarlo Comi, Mario Alberto Battaglia, Francesco Patti, Marco Salvetti, Gianmarco Abbadessa, Umberto Aguglia, Lia Allegorico, Beatrice Maria Allegri Rossi, Maria Pia Amato, Pietro Annovazzi, Carlo Antozzi, Lucia Appendino, Sebastiano Arena, Viola Baione, Roberto Balgera, Valeria Barcella, Damiano Baroncini, Caterina Barrilà, Alessandra Bellacosa, Gianmarco Bellucci, Roberto Bergamaschi, Valeria Bergamaschi, Daiana Bezzini, Beatrice Biolzi, Alvino Bisecco, Simona Bonavita, Giovanna Borriello, Chiara Bosa, Antonio Bosco, Francesca Bovis, Marco Bozzali, Laura Brambilla, Maria Buccafusca, Elisabetta Bucciantini, Sebastiano Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano Calabrese, Francesca Calabria, Francesca Caleri, Federico Camilli, Luisa Maria Caniatti, Roberto Cantello, Ruggero Capra, Rocco Capuano, Patrizia Carta, Maria Grazia Celani, Maria Cellerino, Raffaella Cerqua, Clara Chisari, Raffaella Clerici, Marinella Clerico, Gaia Cola, Antonella Conte, Marta Zaffira Conti, Christian Cordano, Susanna Cordera, Francesco Corea, Claudio Correale, Salvatore Cottone, Francesco Crescenzo, Erica Curti, Alessandro d'Ambrosio, Emanuele D'Amico, Maura Chiara Danni, Alessia d'Arma, Vincenzo Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Stefano, Marco Della Cava, Mario di Napoli, Alessia Di Sapio, Renato Docimo, Anna Dutto, Luana Evangelista, Salvatore Fanara, Ferraro Diana, Maria Teresa Ferrò, Cristina Fioretti, Mario Fratta, Jessica Frau, Marzia Fronza, Roberto Furlan, Alberto Gajofatto, Antonio Gallo, Paolo Gallo, Claudio Gasperini, Anna Ghazaryan, Bruno Giometto, Francesca Gobbin, Flora Govone, Franco Granella, Erica Grange, Maria Grazia Grasso, Angelica Guareschi, Clara Guaschino, Simone Guerrieri, Donata Guidetti, Pietro Iaffaldano, Antonio Ianniello, Luigi Iasevoli, Daniele Imperiale, Maria Teresa Infante, Rosa Iodice, Aniello Iovino, Giovanna Konrad, Doriana Landi, Roberta Lanzillo, Caterina Lapucci, Luigi Lavorgna, Maria Rita L'Episcopo, Serena Leva, Giuseppe Liberatore, Marianna Lo Re, Marco Longoni, Leonardo Lopiano, Lorena Lorefice, Matteo Lucchini, Giacomo Lus, Davide Maimone, Maria Malentacchi, Giulia Mallucci, Simona Malucchi, Chiara Rosa Mancinelli, Luca Mancinelli, Paolo Manganotti, Giorgia Teresa Maniscalco, Vittorio Mantero, Sabrina Marangoni, Damiano Marastoni, Fabiana Marinelli, Alessandro Marti, Filippo Martinelli Boneschi, Federco Masserano Zoli, Francesca Matta, Laura Mendozzi, Giuseppe Meucci, Silvia Miante, Giuseppina Miele, Eva Milano, Massimiliano Mirabella, Rosanna Missione, Marcello Moccia, Lucia Moiola, Sara Montepietra, Margherita MontiBragadin, Federico Montini, Roberta Motta, Raffaele Nardone, Carolina Gabri Nicoletti, Eduardo Nobile-Orazio, Agostino Nozzolillo, Marco Onofrj, Riccardo Orlandi, Anna Palmieri, Damiano Paolicelli, Livia Pasquali, Luisa Pastò, Elisabetta Pedrazzoli, Maria Petracca, Alfredo Petrone, Carlo Piantadosi, Anna M Pietroboni, Federica Pinardi, Marta Ponzano, Emilio Portaccio, Mattia Pozzato, Carlo Pozzilli, Luca Prosperini, Alessandra Protti, Paolo Ragonese, Sarah Rasia, Sabrina Realmuto, Anna Repice, Eleonora Rigoni, Maria Teresa Rilla, Francesca Rinaldi, Calogero Marcello Romano, Marco Ronzoni, Marco Rovaris, Francesca Ruscica, Loredana Sabattini, Giuseppe Salemi, Lorenzo Saraceno, Alessia Sartori, Arianna Sartori, Elvira Sbragia, Giuditta Ilaria Scarano, Valentina Scarano, Valentina Schillaci, Maria Sessa, Caterina Sgarito, Grazia Sibilia, Gabriele Siciliano, Alessio Signori, Elisabetta Signoriello, Leonardo Sinisi, Francesca Sireci, Patrizia Sola, Claudio Solaro, Stefano Sotgiu, Maddalena Sparaco, Maria Laura Stromillo, Silvia Strumia, Emanuela Laura Susani, Giulietta Tabiadon, Francesco Teatini, Valentina Tomassini, Simone Tonietti, Clerici Valentina Torri, Carla Tortorella, Simona Toscano, Rocco Totaro, Maria Trotta, Gabriella Turano, Monica Ulivelli, Manzo Valentino, Giovanna Vaula, Domizia Vecchio, Marco Vercellino, Elena Pinuccia Verrengia, Marika Vianello, Eleonora Virgilio, Francesca Vitetta, Stefano Vollaro, Mauro Zaffaroni, Mauro Zampolini, Ignazio Roberto Zarbo, Luigi Zuliani, Pia Sormani, Maria, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Guido Antonio, Confalonieri, Paolo, Alessandra Marfia, Girolama, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Tedeschi, Gioacchino, Comi, Giancarlo, Alberto Battaglia, Mario, Patti, Francesco, Salvetti, Marco, Abbadessa, Gianmarco, Aguglia, Umberto, Allegorico, Lia, Maria Allegri Rossi, Beatrice, Pia Amato, Maria, Annovazzi, Pietro, Antozzi, Carlo, Appendino, Lucia, Arena, Sebastiano, Baione, Viola, Balgera, Roberto, Barcella, Valeria, Baroncini, Damiano, Barrilà, Caterina, Bellacosa, Alessandra, Bellucci, Gianmarco, Bergamaschi, Roberto, Bergamaschi, Valeria, Bezzini, Daiana, Biolzi, Beatrice, Bisecco, Alvino, Bonavita, Simona, Borriello, Giovanna, Bosa, Chiara, Bosco, Antonio, Bovis, Francesca, Bozzali, Marco, Brambilla, Laura, Buccafusca, Maria, Bucciantini, Elisabetta, Bucello, Sebastiano, Chiara Buscarinu, Maria, Paola Cabboi, Maria, Calabrese, Massimiliano, Calabria, Francesca, Caleri, Francesca, Camilli, Federico, Maria Caniatti, Luisa, Cantello, Roberto, Capra, Ruggero, Capuano, Rocco, Carta, Patrizia, Grazia Celani, Maria, Cellerino, Maria, Cerqua, Raffaella, Chisari, Clara, Clerici, Raffaella, Clerico, Marinella, Cola, Gaia, Conte, Antonella, Zaffira Conti, Marta, Cordano, Christian, Cordera, Susanna, Corea, Francesco, Correale, Claudio, Cottone, Salvatore, Crescenzo, Francesco, Curti, Erica, D'Ambrosio, Alessandro, D'Amico, Emanuele, Chiara Danni, Maura, D'Arma, Alessia, Dattola, Vincenzo, de Biase, Stefano, De Luca, Giovanna, Federica De Mercanti, Stefania, De Mitri, Paolo, De Stefano, Nicola, Della Cava, Marco, di Napoli, Mario, Di Sapio, Alessia, Docimo, Renato, Dutto, Anna, Evangelista, Luana, Fanara, Salvatore, Diana, Ferraro, Teresa Ferrò, Maria, Fioretti, Cristina, Fratta, Mario, Frau, Jessica, Fronza, Marzia, Furlan, Roberto, Gajofatto, Alberto, Gallo, Antonio, Gallo, Paolo, Gasperini, Claudio, Ghazaryan, Anna, Giometto, Bruno, Gobbin, Francesca, Govone, Flora, Granella, Franco, Grange, Erica, Grazia Grasso, Maria, Guareschi, Angelica, Guaschino, Clara, Guerrieri, Simone, Guidetti, Donata, Iaffaldano, Pietro, Ianniello, Antonio, Iasevoli, Luigi, Imperiale, Daniele, Teresa Infante, Maria, Iodice, Rosa, Iovino, Aniello, Konrad, Giovanna, Landi, Doriana, Lanzillo, Roberta, Lapucci, Caterina, Lavorgna, Luigi, Rita L'Episcopo, Maria, Leva, Serena, Liberatore, Giuseppe, Lo Re, Marianna, Longoni, Marco, Lopiano, Leonardo, Lorefice, Lorena, Lucchini, Matteo, Lus, Giacomo, Maimone, Davide, Malentacchi, Maria, Mallucci, Giulia, Malucchi, Simona, Rosa Mancinelli, Chiara, Mancinelli, Luca, Manganotti, Paolo, Teresa Maniscalco, Giorgia, Mantero, Vittorio, Marangoni, Sabrina, Marastoni, Damiano, Marinelli, Fabiana, Marti, Alessandro, Martinelli Boneschi, Filippo, Masserano Zoli, Federco, Matta, Francesca, Mendozzi, Laura, Meucci, Giuseppe, Miante, Silvia, Miele, Giuseppina, Milano, Eva, Mirabella, Massimiliano, Missione, Rosanna, Moccia, Marcello, Moiola, Lucia, Montepietra, Sara, Montibragadin, Margherita, Montini, Federico, Motta, Roberta, Nardone, Raffaele, Gabri Nicoletti, Carolina, Nobile-Orazio, Eduardo, Nozzolillo, Agostino, Onofrj, Marco, Orlandi, Riccardo, Palmieri, Anna, Paolicelli, Damiano, Pasquali, Livia, Pastò, Luisa, Pedrazzoli, Elisabetta, Petracca, Maria, Petrone, Alfredo, Piantadosi, Carlo, M Pietroboni, Anna, Pinardi, Federica, Ponzano, Marta, Portaccio, Emilio, Pozzato, Mattia, Pozzilli, Carlo, Prosperini, Luca, Protti, Alessandra, Ragonese, Paolo, Rasia, Sarah, Realmuto, Sabrina, Repice, Anna, Rigoni, Eleonora, Teresa Rilla, Maria, Rinaldi, Francesca, Marcello Romano, Calogero, Ronzoni, Marco, Rovaris, Marco, Ruscica, Francesca, Sabattini, Loredana, Salemi, Giuseppe, Saraceno, Lorenzo, Sartori, Alessia, Sartori, Arianna, Sbragia, Elvira, Ilaria Scarano, Giuditta, Scarano, Valentina, Schillaci, Valentina, Sessa, Maria, Sgarito, Caterina, Sibilia, Grazia, Siciliano, Gabriele, Signori, Alessio, Signoriello, Elisabetta, Sinisi, Leonardo, Sireci, Francesca, Sola, Patrizia, Solaro, Claudio, Sotgiu, Stefano, Sparaco, Maddalena, Laura Stromillo, Maria, Strumia, Silvia, Laura Susani, Emanuela, Tabiadon, Giulietta, Teatini, Francesco, Tomassini, Valentina, Tonietti, Simone, Valentina Torri, Clerici, Tortorella, Carla, Toscano, Simona, Totaro, Rocco, Trotta, Maria Consiglia, Turano, Gabriella, Ulivelli, Monica, Valentino, Manzo, Vaula, Giovanna, Vecchio, Domizia, Vercellino, Marco, Pinuccia Verrengia, Elena, Vianello, Marika, Virgilio, Eleonora, Vitetta, Francesca, Vollaro, Stefano, Zaffaroni, Mauro, Zampolini, Mauro, Roberto Zarbo, Ignazio, Zuliani, Luigi, Sormani, M. P., Schiavetti, I., Carmisciano, L., Cordioli, C., Filippi, M., Radaelli, M., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Cocco, E., Scandellari, C., Cavalla, P., Pesci, I., Zito, A., Confalonieri, P., Marfia, G. A., Perini, P., Inglese, M., Trojano, M., Brescia Morra, V., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Zito, Antonio, BRESCIA MORRA, Vincenzo, Trotta, Maria, Sormani, Maria Pia, Marfia, Girolama Alessandra, and Battaglia, Mario Alberto
Subjects: Adult, Male, medicine.medical_specialty, Multiple Sclerosis, Coronavirus disease 2019 (COVID-19), Population, Intensive Care Unit, COVID-19, Cohort Studies, Comorbidity, Female, Hospitalization, Humans, Intensive Care Units, Italy, Middle Aged, Retrospective Studies, Risk Factors, Severity of Illness Index, Context (language use), Settore MED/26, Lower risk, Retrospective Studie, Internal medicine, Multiple Sclerosi, Medicine, In patient, National level, education, education.field_of_study, Expanded Disability Status Scale, business.industry, Risk Factor, Ethics committee, medicine.disease, Icu admission, Settore MED/26 - NEUROLOGIA, Neurology, Relative risk, Family medicine, Cohort, Honorarium, Observational study, Neurology (clinical), Cohort Studie, business, Human
Abstract: Background: It is unclear how multiple sclerosis (MS) affects the severity of Covid-19. Methods: Hospitalization, Intensive Care Unit (ICU) admission and death after Covid-19 diagnosis of 1362 MS patients were compared to the age and sex-matched Italian population in a retrospective observational case-cohort study with population-based control. The observed vs the expected events were compared in the whole MS cohort and in different subgroups (higher-risk: EDSS>3 or at least one comorbidity, lower-risk: EDSS
Published: 2021

33. The negative effects of COVID-19 and national lockdown on emergency surgery morbidity due to delayed access

Author: Giovanni Maria Guarrera, Saverio Tateo, Liliana Mereu, Francesco Antonio Ciarleglio, Mario Grattarola, Alessandro Carrara, Cai Tommaso, Marta Rigoni, Alberto Brolese, Antonio Ferro, Gianni Malossini, Giandomenico Nollo, Truls E. Bjerklund Johansen, Pier Paolo Benetollo, and Giuseppe Tirone
Subjects: Male, Blood transfusion, Complications, medicine.medical_treatment, Comorbidity, 0302 clinical medicine, 030212 general & internal medicine, education.field_of_study, Emergency Service, Medical emergencies. Critical care. Intensive care. First aid, Middle Aged, Operative, COVID-19 disease, Delayed access, Emergency surgery, Surgical care, Adult, Aged, COVID-19, Communicable Disease Control, Emergency Service, Hospital, Female, Follow-Up Studies, Hospitalization, Humans, Italy, Retrospective Studies, Surgical Procedures, Operative, Time-to-Treatment, Emergencies, Pandemics, 030220 oncology & carcinogenesis, Cohort, Emergency Medicine, Research Article, medicine.medical_specialty, RD1-811, Population, Subgroup analysis, 03 medical and health sciences, Hospital, Internal medicine, medicine, Medical history, education, Surgical Procedures, business.industry, RC86-88.9, Retrospective cohort study, Emergency department, medicine.disease, Surgery, business
Abstract: Background The aim of this retrospective comparative study was to assess the impact of COVID-19 and delayed emergency department access on emergency surgery outcomes, by comparing the main clinical outcomes in the period March–May 2019 (group 1) with the same period during the national COVID-19 lockdown in Italy (March–May 2020, group 2). Methods A comparison (groups 1 versus 2) and subgroup analysis were performed between patients’ demographic, medical history, surgical, clinical and management characteristics. Results Two-hundred forty-six patients were included, 137 in group 1 and 109 in group 2 (p = 0.03). No significant differences were observed in the peri-operative characteristics of the two groups. A declared delay in access to hospital and preoperative SARS-CoV-2 infection rates were 15.5% and 5.8%, respectively in group 2. The overall morbidity (OR = 2.22, 95% CI 1.08–4.55, p = 0.03) and 30-day mortality (OR = 1.34, 95% CI 0.33–5.50, =0.68) were significantly higher in group 2. The delayed access cohort showed a close correlation with increased morbidity (OR = 3.19, 95% CI 0.89–11.44, p = 0.07), blood transfusion (OR = 5.13, 95% CI 1.05–25.15, p = 0.04) and 30-day mortality risk (OR = 8.00, 95% CI 1.01–63.23, p = 0.05). SARS-CoV-2-positive patients had higher risk of blood transfusion (20% vs 7.8%, p = 0.37) and ICU admissions (20% vs 2.6%, p = 0.17) and a longer median LOS (9 days vs 4 days, p = 0.11). Conclusions This article provides enhanced understanding of the effects of the COVID-19 pandemic on patient access to emergency surgical care. Our findings suggest that COVID-19 changed the quality of surgical care with poorer prognosis and higher morbidity rates. Delayed emergency department access and a “filter effect” induced by a fear of COVID-19 infection in the population resulted in only the most severe cases reaching the emergency department in time.
Published: 2021
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34. Rigoni-Stern and medical statistics. A nineteenth-century approach to cancer research

Author: Joseph Scotto and John C. Bailar
Subjects: History, business.industry, Statistics as Topic, MEDLINE, Historical Article, Biography, History, 19th Century, Medical statistics, Stern, Italy, Neoplasms, Medicine, Geriatrics and Gerontology, business, Classics
Published: 1969

35. Time-resolved multimode heterodyne detection for dissecting coherent states of matter

Author: Francesca Giusti, Filippo Glerean, Daniele Fausti, Jonathan O. Tollerud, Giacomo Jarc, A. Marciniak, Giorgia Sparapassi, Enrico Maria Rigoni, Angela Montanaro, Glerean, F., Jarc, G., Marciniak, A., Giusti, F., Sparapassi, G., Montanaro, A., Rigoni, E. M., Tollerud, J. O., and Fausti, D.
Subjects: spectroscopy, heterodyne, Phonon, Ultrafast, coherent, phonon, quadrature, multimode, homodyne, Phase (waves), FOS: Physical sciences, Applied Physics (physics.app-ph), 02 engineering and technology, 01 natural sciences, 010309 optics, Momentum, Optics, 0103 physical sciences, Heterodyne detection, Quantum information, Physics, business.industry, Time evolution, Physics - Applied Physics, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, Femtosecond, Coherent states, Atomic physics, 0210 nano-technology, business, Optics (physics.optics), Physics - Optics
Abstract: Unveiling and controlling the time evolution of the momentum and position of low energy excitations such as phonons, magnons, and electronic excitation is the key to attain coherently driven new functionalities of materials. Here we report the implementation of femtosecond time- and frequency-resolved multimode heterodyne detection and show that it allows for independent measurement of the time evolution of the position and momentum of the atoms in coherent vibrational states in α -quartz. The time dependence of the probe field quadratures reveals that their amplitude is maximally changed when the atoms have maximum momentum, while their phase encodes a different information and evolves proportionally to the instantaneous atomic positon. We stress that this methodology, providing the mean to map both momentum and position in one optical observable, may be of relevance for both quantum information technologies and time-domain studies on complex materials.
Published: 2020

36. Analysts’ recommendations and the market impact of the valuation methods

Author: Elisa Cavezzali, Pierpaolo Pattitoni, Ugo Rigoni, Enrico Maria Cervellati, Cavezzali, Elisa, Cervellati, Enrico Maria, Pattitoni, Pierpaolo, and Rigoni, Ugo
Subjects: Content Analysis, Economics and Econometrics, Market Reaction, 050208 finance, Actuarial science, Public Administration, Strategy and Management, 05 social sciences, Event study, Market reaction, Equity Analysts, Valuation Methods, Market Reaction, Content Analysis, Event Study, 050201 accounting, Equity Analysts, Event Study, Settore SECS-P/09 - Finanza Aziendale, Content analysis, 0502 economics and business, Business, Business and International Management, Valuation Methods, Market impact, Finance
Abstract: Despite its importance, the informative value of the analysts’ valuation methods has not been thoroughly examined in the literature. Such an issue is relevant with regard to the concerns on analysts’ objectivity. We test whether investors’ reaction is jointly influenced by recommendations and target revisions and mainly by valuation method used because it summarizes the information considered to be relevant by the analysts. We analyse the market reaction to recommendation revisions with an event study methodology, calculating market-adjusted abnormal returns at the report release date. We run regressions to test the market impact of recommendations and target price revisions, as well as their interaction, and we then focus on testing several models to discern market reaction to distinct valuation methods. We show that market reaction is influenced by the valuation methods used in their reports. The majority of previous studies relying on commercial databases report the market reaction in relation to analysts’ recommendations, target prices or earnings forecasts, often overlooking the content of the reports and the methodology used therein. This is due to an information constraint of commercial databases, normally including only the above-mentioned synthetic variables. A notable exception is Asquith, Mikhail, and Au (2005) who find no relation between the market reaction and the valuation methods used by analysts. Compared to Asquith et al. (2005), our research uses a larger database and finds a different result. We show the market reacts differently to distinct valuation methods, without favouring the theoretically more correct ones based on discounting cash flows. We also find that the market reaction is larger when the analysts support their recommendation with more than one valuation method. Our research shows that the market pays attention to the content of the reports and analysts can be more influential when they use more valuation methodologies to cross-check their estimates.
Published: 2019
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37. The Aeneid and the Modern World

Author: J.R. O’Neill and Adam Rigoni
Subjects: Literature, History, business.industry, EPIC, business
Published: 2021
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38. Is corporate social responsibility an agency problem? An empirical note from takeovers

Author: Ugo Rigoni, Duc Khuong Nguyen, Nazim Hussain, Mussa Hussaini, and Research programme I&O
Subjects: Settore SECS-P/11 - Economia degli Intermediari Finanziari, Acquirers, 050208 finance, business.industry, 05 social sciences, Principal–agent problem, Accounting, Agency problems, Large sample, CSR performance, Acquirers, Takeover premium, Agency problems, Takeover premium, Shareholder, 0502 economics and business, Agency (sociology), Corporate social responsibility, 050207 economics, CSR performance, business, Finance
Abstract: We rely on the agency motives of the takeover premium to empirically examine whether and how the acquirer's corporate social responsibility (CSR) performance influences the premiums paid in takeovers. Using a large sample of US takeovers that took place over the period from 1992 to 2014, our results mainly reveal that higher CSR performance at the acquirer level is associated with higher takeover premium which is consistent with the shareholder expense view. Our results continue to hold after a battery of additional analyses.
Published: 2021

39. Pneumococcal and influenza vaccination coverage of heart failure patients: still a long way to go

Author: Sylvain Aguilhon, Anne Jalabert, Nicolas Chapet, M.L Laugier, Cyril Breuker, Y. Audurier, A. Maire, Florence Leclercq, François Roubille, G. De Barry, P Laffont-Lozes, M Rigoni, Jean-Luc Pasquié, and Audrey Castet-Nicolas
Subjects: medicine.medical_specialty, business.industry, Heart failure, Vaccination coverage, medicine, Cardiology and Cardiovascular Medicine, Intensive care medicine, medicine.disease, business
Abstract: In patients with heart failure (HF), respiratory infections are responsible for acute exacerbation and increased hospitalization. Vaccination may reduce the incidence and/or severity of respiratory infections, and thereby, reduce the risk of HF exacerbation. Despite current recommendation, vaccination coverage (VC) for patients with HF remains far too limited. To study the VC of HF patients followed in our hospital and to precise the strategies desired by the patients in order to carry out the vaccination. This was a prospective monocentric descriptive study conducted between December 2019 and January 2021. Patients with HF history hospitalized in cardiology unit (CU) and patients in a HF telemonitoring program (TP) were included. An interview was conducted by a pharmacist to find out the patient's vaccination status regarding influenza and pneumococcus, together with socio-demographic clinical data. During the interview for non-vaccinated patients, opinion and willingness to be vaccinated were obtained. Data from 335 patients were collected (185 in CU, 150 in TP). The mean age was 69.3 years, and sex ratio was 2.6. About 65% were vaccinated against influenza in the last year (60% in CU, 72% in TP, p=0.022) and 22% had pneumococcal vaccination in the last 5 years (11% in CU, 35% in TP, p The VC of HF patients remains insufficient, particularly against pneumococcus, as described by Kopp and al. Patients in TP are more vaccinated than patients in CU, which could involve better management. Moreover, the low rate of vaccinated patients is mainly explained by a lack of awareness, as most of the unvaccinated would like to be vaccinated. About 2/3 of patients wanted to be vaccinated by their GP, and thus play a major role in their global care. The higher vaccination rate for influenza, which unlike pneumococcus benefits from a national vaccination campaign, demonstrates that improvements are needed in the institutional promotion of vaccination for HF patients. Funding Acknowledgement Type of funding sources: None.
Published: 2021
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40. NEWS2 is a valuable tool for appropriate clinical management of COVID-19 patients

Author: Livia Delle Donne, Giandomenico Nollo, Susanna Cozzio, Marta Rigoni, and Emanuele Torri
Subjects: hospital mortality, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, early warning score, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MEDLINE, COVID-19, Hospital mortality, NEWS2, Early warning score, Settore MED/01 - Statistica Medica, ROC, humans, ROC Curve, retrospective studies, Internal Medicine, Humans, Medicine, business, Intensive care medicine, Letter to the Editor, Retrospective Studies
Published: 2021
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41. Morphological MRI of knee cartilage: repeatability and reproducibility of damage evaluation and correlation with gross pathology examination

Author: Sabino Walter Della Sala, Marta Rigoni, Luisa Ventura, Marinella Neri, Alessandro Marinetti, Federico Piccoli, Michela Masè, Francesco Tessarolo, Andrea Falzone, Giandomenico Nollo, and Fabrizio Cortese
Subjects: Reproducibility, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Ultrasound, Magnetic resonance imaging, Interventional radiology, General Medicine, Repeatability, Condyle, 030218 nuclear medicine & medical imaging, Gross examination, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Medicine, Radiology, Nuclear Medicine and imaging, Radiology, business, Neuroradiology
Abstract: To assess the performance of a morphological evaluation, based on a clinically relevant magnetic resonance imaging (MRI) protocol, in scoring the severity of knee cartilage damage. Specifically, to evaluate the reproducibility, repeatability, and agreement of MRI evaluation with the gross pathology examination (GPE) of the tissue. MRI of the knee was performed the day before surgery in 23 patients undergoing total knee arthroplasty. Osteochondral tissue resections were collected and chondral defects were scored by GPE according to a semi-quantitative scale. MR images were independently scored by four radiologists, who assessed the severity of chondral damage according to equivalent criteria. Inter- and intra-rater agreements of MRI evaluations were assessed. Correlation, precision, and accuracy metrics between MRI and GPE scores were calculated. Moderate to substantial inter-rater agreement in scoring cartilage damage by MRI was found among radiologists. Intra-rater agreement was higher than 96%. A significant positive monotonic correlation between GPE and MRI scores was observed for all radiologists, although higher correlation values were obtained by radiologists with expertise in musculoskeletal radiology and/or longer experience. The accuracy of MRI scores displayed a spatial pattern, characterized by lesion overestimation in the lateral condyle and underestimation in the medial condyle with respect to GPE. Evaluation of knee cartilage morphology by MRI is a reproducible and repeatable technique, which positively correlates with GPE. Clinical expertise in musculoskeletal radiology positively impacts the evaluation reliability. These findings may help to address limitations in MRI evaluation of knee chondral lesions, thus improving MRI assessment of knee cartilage. • MRI evaluation of knee cartilage shows moderate to strong correlation with gross pathology examination. • MRI evaluation overestimates cartilage damage in the lateral condyle and underestimates it in the medial condyle. • Education and experience of the radiologist play a role in MRI evaluation of knee chondral lesions.
Published: 2020
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42. 'Long COVID' follow-up pathway: results of longitudinal cohort study to investigate 6- and 12-month outcomes after hospitalization for SARS-CoV-2 infection

Author: Marta Rigoni, Livia Delle Donne, Susanna Cozzio, Sebastiano Rizzardo, Emanuele Torri, Lorenza Lenzi, Giandomenico Nollo, and Andrea Falzone
Subjects: medicine.medical_specialty, business.industry, Internal medicine, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine, Longitudinal cohort, business
Abstract: Long-term sequelae of symptomatic infection caused by SARS-CoV-2 are largely undiscovered. We performed a prospective cohort study on consecutively hospitalized Sars-CoV-2 patients (March-May 2020) for evaluating COVID-19 outcomes at 6 and 12 months. After hospital discharge, patients were addressed to two follow-up pathways based on respiratory support needed during hospitalization. Outcomes were assessed by telephone consultation or ambulatory visit. Among 471 patients, 81.6% received no respiratory support during hospitalization; 8.2% received non-invasive ventilation; 0.2% required invasive mechanical ventilation (IMV). 64 patients died during hospitalization, therefore 407 were enrolled for follow-up. At 6 months, among 355patients, the 27.0% had any symptoms, 19.4% dyspnea, 5.4% neurological symptoms. Fifty-two out of 104 had major damages in interstitial Computed Tomography images. IMV patients had higher probability to suffer of neurological symptoms (OR=4.12, p=0.01). At 12 months, among 344, the 24.4% suffered on any symptoms, 14.0% dyspnea, 10.0% neurological symptoms. Severe interstitial lesions were present in 37 out of 47 investigated patients. IMV patients in respect to no respiratory support, had higher probability of experiencing symptoms (OR=3.51, p
Published: 2021
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43. Dynamic analysis of lower leg muscles response to whole body vibration stimulation at different frequencies and postures: implications for training

Author: Paolo Bifulco, Isotta Rigoni, Antonio Fratini, and Tecla Bonci
Subjects: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Vibratory stimulation, Stimulation, Squat, Electromyography, Leg muscle, Physical medicine and rehabilitation, Calf muscle, Medicine, Whole body vibration, medicine.symptom, business, Muscle contraction
Abstract: PurposeTo characterise the mechanical and neuromuscular response of lower limb muscles in subjects undergoing Whole Body Vibration (WBV) at different frequencies while holding two static postures.MethodsTwenty-five participants underwent WBV at 15, 20, 25 and 30 Hz while holding a static ‘hack squat’ and on ‘fore feet’ posture. Surface electromyography (sEMG) and soft tissue accelerations were collected from Gastrocnemius Lateralis (GL), Soleus (SOL) and Tibialis Anterior (TA) muscles.ResultsOnly specific WBV settings led to a significant increase in muscle contraction. Specifically, the WBV-induced activation of SOL and GL was maximal in fore-feet and in response to higher frequencies. Estimated displacement at muscle bellies revealed a resonant pattern never highlighted before. After stimulation starts, muscle oscillation reaches a peak followed by a drop and a further stabilisation (few seconds after the peak) that suggests the occurrence of a neuromuscular activation to reduce the vibration-induced oscillation.ConclusionLower leg muscles need a response time to tune to a vibratory stimulation, which discourages the use of dynamic exercises on vibrating platforms. To maximize calf muscle response to WBVs, a stimulation frequency in the range of 25-30 Hz and an ‘on fore feet’ posture are recommended.
Published: 2021
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44. Typical within and between person variability in non-invasive ventilator derived variables among clinically stable, long-term users

Author: Linda Rautela, Marnie Graco, Vishnu Jeganathan, David J Berlowitz, Liam M. Hannan, Krisha Saravanan, Mark E Howard, Simon Conti, and Alyssa Rigoni
Subjects: Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Respiratory rate, assisted ventilation, 03 medical and health sciences, Diseases of the respiratory system, 0302 clinical medicine, Internal medicine, Tidal Volume, Medicine, Humans, Prospective Studies, Prospective cohort study, Tidal volume, Noninvasive Ventilation, Ventilators, Mechanical, RC705-779, business.industry, Non invasive, clinical epidemiology, Middle Aged, Respiration, Artificial, 030228 respiratory system, Cohort, Breathing, non invasive ventilation, Female, business, Sleep, Body mass index, 030217 neurology & neurosurgery, Respiratory minute volume
Abstract: BackgroundDespite increasing capacity to remotely monitor non-invasive ventilation (NIV), how remote data varies from day to day and person to person is poorly described.MethodsSingle-centre, 2-month, prospective study of clinically stable adults on long-term NIV which aimed to document NIV-device variability. Participants were switched to a ventilator with tele-monitoring capabilities. Ventilation settings and masking were not altered. Raw, extensible markup language data files were provided directly from Philips Respironics (EncoreAnywhere). A nested analysis of variance was conducted on each ventilator variable to apportion the relative variation between and within participants.ResultsTwenty-nine people were recruited (four withdrew, one had insufficient data for analyses; 1364 days of data). Mean age was 54.0 years (SD 18.4), 58.3% male with body mass index of 37.0 kg/m2 (13.7). Mean adherence was 8.53 (2.23) hours/day and all participants had adherence >4 hours/day. Variance in ventilator-derived indices was predominantly driven by differences between participants; usage (61% between vs 39% within), Apnoea–Hypopnoea Index (71% vs 29%), unintentional (64% vs 36%) and total leak (83% vs 17%), tidal volume (93% vs 7%), minute ventilation (92% vs 8%), respiratory rate (92% vs 8%) and percentage of triggered breaths (93% vs 7%).InterpretationIn this clinically stable cohort, all device-derived indices were more varied between users than the day-to-day variation within individuals. We speculate that normative ranges and thresholds for clinical intervention need to be individualised, and further research is necessary to determine the clinically important relationships between clinician targets for therapy and patient-reported outcomes.
Published: 2021

45. A Simple and Efficient Visible Light Photodetector based on Co3O4/ZnO Composite

Author: Zafar Hussian Ibupoto, Ayman Nafady, Aneela Tahira, Razan A. Alshgari, Raffaello Mazzaro, Asma A. Alothman, Shoyebmohamad F. Shaikh, and Federica Rigoni
Subjects: Materials science, business.industry, Nanowire, Oxide, Photodetector, Heterojunction, Tin oxide, chemistry.chemical_compound, chemistry, Optoelectronics, Nanorod, business, Cobalt oxide, Visible spectrum
Abstract: Herein, we propose for the first time visible light photodetector based on n-type ZnO nanorods decorated with p-type Co3O4 nanowires. The heterojunction was fabricated on fluorine doped tin oxide (FTO) glass substrate by low temperature aqueous chemical growth method. ZnO exhibits nanorod morphology and cobalt oxide possesses nanowire shape with sharp tail. Energy dispersive spectroscopy (EDS) confirmed the presence of Zn, O, and Co elements in the heterojunction. ZnO and Co3O4 have hexagonal and cubic phases, respectively, as confirmed by XRD. The dense and perpendicular ZnO nanorods are acting as a scattering layer for visible light, while Co3O4 nanowires act as a visible-light absorber. The all oxide p-n junction can operate as visible light photodetector. Furthermore, the heterojunction also shows a reproducible and fast response for the detection of visible light. Optimization of the device is needed (presence of buffer layers, tuning a thickness of the optical absorber) to improve its functionalities.
Published: 2021
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46. Quantitative MRI T2 Mapping is Able to Assess Tissue Quality After Reparative and Regenerative Treatments of Osteochondral Lesions of the Talus

Author: Leonardo Puddu, Giulio Rizzo, Alessandro Cristoforetti, Francesco Tessarolo, Giandomenico Nollo, Marta Rigoni, Fabrizio Cortese, Sabino Walter Della Sala, and Alessandro Marinetti
Subjects: Cartilage, Articular, Population, 030218 nuclear medicine & medical imaging, Talus, Lesion, 03 medical and health sciences, Arthroscopy, 0302 clinical medicine, ankle, medicine, Humans, Radiology, Nuclear Medicine and imaging, articular cartilage, Prospective Studies, T2 relaxation time, education, Prospective cohort study, Research Articles, education.field_of_study, business.industry, Cartilage, Magnetic Resonance Imaging, Transplantation, Exact test, medicine.anatomical_structure, Musculoskeletal, Fibrocartilage, Ankle, medicine.symptom, Nuclear medicine, business, Research Article
Abstract: Background Quantitative MRI has potential for tissue characterization after reparative and regenerative surgical treatment of osteochondral lesions of the talus (OCLTs). However available data is inconclusive and quantitative sequences can be difficult to implement in real‐time clinical application. Purpose To assess the potential of T2 mapping in discriminating articular tissue characteristics after reparative and regenerative surgery of OCLTs in real‐world clinical settings. Study Type Observational and prospective cohort study. Population 15 OCLT patients who had received either reparative treatment with arthroscopic microfracture surgery (MFS) for a grade I lesion or regenerative treatment with bone marrow derived cell transplantation (BMDCT) for a grade II lesion. Field Strength/Sequence 1.5 T, proton density weighted TSE, T2‐weighted true fast imaging with steady‐state‐free precession and multi‐echo T2 mapping sequences. Assessment Patients were evaluated at a minimum postoperative follow‐up of 24 months. T2 maps of the ankle were generated and the distribution of T2 values was analyzed in manually identified volumes of interest (VOIs) for both treated lesions (TX) and healthy cartilage (CTRL). The amount of fibrocartilage, hyaline‐like and remodeling tissue in TX VOIs was obtained, based on T2 thresholds from CTRL VOIs. Statistical Tests Fisher's exact test for categorical data, nonparametric Mann–Whitney U test for continuous data. The statistical significance level was P 45 msec were considered as representative for fibrocartilage, hyaline‐like and remodeling tissue, respectively. Tissue composition of the two treatment groups was different, with significantly more fibrocartilage (+28%) and less hyaline‐like tissue (−15%) in MFS than in BMDCT treated lesions. No difference in healthy tissue composition was found between the two groups (P = 0.75). Data Conclusions T2 mapping of surgically treated OCLTs can provide quantitative information about the type and amount of newly formed tissue at the lesion site, thereby facilitating surgical follow‐up in a real‐word clinical setting. Level of Evidence 2 Technical Efficacy Stage 3
Published: 2021

47. Effectiveness of two rehabilitation treatments in the modulation of inflammation during the acute phase in patients with knee prostheses and assessment of the role of the diet in determining post-surgical inflammation

Author: Sergio Rigoni, Davide Baù, Luca Tagliaro, and Mario Scapin
Subjects: 030222 orthopedics, medicine.medical_specialty, Mediterranean diet, business.industry, Standard treatment, Connective tissue, Inflammation, 030229 sport sciences, Systemic inflammation, Article, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Manual lymphatic drainage, Lymphatic system, medicine.anatomical_structure, Internal medicine, Medicine, Orthopedics and Sports Medicine, medicine.symptom, business
Abstract: Clinical trial number NCT04580069. Background Total knee arthroplasty is associated with an elevated inflammatory response both at a local and systemic level. The main objective of this study is to demonstrate the effectiveness of lymphatic drainage and connective tissue techniques in modulating systemic inflammation. Another objective is to evaluate the existence, at baseline, of a correlation between the inflammation indices and the level of adherence to the Mediterranean diet. Methods 34 patients were recruited, and divided into three groups. The control group followed the normal rehabilitation protocol. The other two groups were subjected, in addition to the standard treatment, to manual lymphatic drainage treatment or connective tissue techniques. The outcomes were recorded in three stages: upon entering the hospital, 1 week after entry and at follow-up 21 days after surgery. Results The results of the study showed that both methods, compared with the standard treatment only, positively influenced the final outcomes. In regard to the systemic inflammation, lymphatic drainage and connective techniques showed equal efficacy and similar timing in modulating ESR, while they differ in how they affect CRP. With regard to the local inflammation, the effectiveness of both methods was confirmed with some differences in the location. Finally, analysis of the correlation between inflammatory T0 indices and adherence to the Mediterranean diet showed that patients with higher adhesion index have on average lower PCR, EDO and EDU values. Conclusions The post-surgical inflammatory pattern can be positively modified by the rehabilitation methods analyzed, albeit with different methodologies and timing. The influence of the diet on inflammatory parameters, although less evident, seems to show encouraging results worth of further studies.
Published: 2021

48. Web-based streamed waveform display using MDSplus events and Node.js

Author: A. Rigoni, Gabriele Manduchi, C. Taliercio, G. Moro, and Adriano Luchetta
Subjects: HTML5, Remote Participation, Multicast, business.industry, Network packet, Computer science, Mechanical Engineering, Real-time computing, Data acquisition, MDSplus, 01 natural sciences, 010305 fluids & plasmas, Visualization, Data visualization, Nuclear Energy and Engineering, 0103 physical sciences, Node (computer science), Web application, General Materials Science, 010306 general physics, business, Virtual Laboratory, Web based visualization, Civil and Structural Engineering
Abstract: Streamed data visualization is a new requirement for long lasting discharges and more in general for every long lasting related experiment, such as the ITER Neutral Beam test facility. A prerequisite for live visualization is the ability of the underlying data system to support streaming in data acquisition. Data streaming is supported in MDSplus, a widely adopted data system in fusion research, by means of segments. A signal in MDSplus is stored as a sequence of segments that can be saved individually as soon as the associated data chunk is available. In this way, at any time during the experiment sequence, segments stored so far are readily available and can be used for on-line analysis and visualization. On-line visualization is routinely performed during long lasting experiments, but implementing streamed data visualization, such as strip charts, would overload the data system, especially if a large number of charts are being displayed. A different approach for streamed data visualization is proposed here, using MDSplus events, rather than directly accessing stored data. MDSplus events are used to synchronize components during the experiment sequence, using a multicast organization. A listener can register for a given event name and it will be notified when an event with that name is generated. Events can bring data and are implemented as UDP multicast packets. A data acquisition program can therefore, in addition to using MDSplus for streaming data segments, generate MDSplus events bringing the most recent chunk of samples. In order to make data carried by events available to Web applications, a Node.js server has been developed, listening for the UDP packets and updating the connected Web clients using HTML5 Server Sent Events. In turn, Web client will update the displayed waveforms using chart js. Compared with other approaches for streamed data visualization, the presented one offers several advantages. Firstly, MDSplus events represent a much lighter solution in respect to repeatedly accessing stored data in pulse files. Then, Node.js proved a very effective environment for originating the Web pages and to implement the bridge between MDSplus events and HTML5 Server Sent events, resulting in an amazingly low number of lines of JavaScript code. Finally, chart js proved an effective tool for waveform display in Web pages, with a stunning performance in animation.
Published: 2020
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49. Self-Powered Photodetectors Based on Core-Shell ZnO-Co3O4 Nanowire Heterojunctions

Author: Isabella Concina, Edgar Abarca Morales, Alberto Vomiero, Nils Almqvist, Pedram Ghamgosar, Federica Rigoni, Vittorio Morandi, Shujie You, Mojtaba Gilzad Kohan, Raffaello Mazzaro, Ghamgosar P., Rigoni F., Kohan M.G., You S., Morales E.A., Mazzaro R., Morandi V., Almqvist N., Concina I., and Vomiero A.
Subjects: Materials science, Nanostructure, Settore ING-IND/22 - Scienza e Tecnologia dei Materiali, Nanowire, Photodetector, 02 engineering and technology, Specific detectivity, 010402 general chemistry, 7. Clean energy, 01 natural sciences, Responsivity, photovoltaic photodetector, all-oxide p-n heterojunction, nanowire geometry, self-powered photodetector, ZnO-Co, 3, O, 4, core-shell, General Materials Science, Electronic band structure, ZnO-Co3O4 core-shell, business.industry, Heterojunction, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Experimental physics, Optoelectronics, 0210 nano-technology, business
Abstract: Self-powered photodetectors operating in the UV-visible-NIR window made of environmentally friendly, earth abundant, and cheap materials are appealing systems to exploit natural solar radiation without external power sources. In this study, we propose a new p-n junction nanostructure, based on a ZnO-Co3O4 core-shell nanowire (NW) system, with a suitable electronic band structure and improved light absorption, charge transport, and charge collection, to build an efficient UV-visible-NIR p-n heterojunction photodetector. Ultrathin Co3O4 films (in the range 1-15 nm) were sputter-deposited on hydrothermally grown ZnO NW arrays. The effect of a thin layer of the Al2O3 buffer layer between ZnO and Co3O4 was investigated, which may inhibit charge recombination, boosting device performance. The photoresponse of the ZnO-Al2O3-Co3O4 system at zero bias is 6 times higher compared to that of ZnO-Co3O4. The responsivity (R) and specific detectivity (D*) of the best device were 21.80 mA W-1 and 4.12 x 10(12) Jones, respectively. These results suggest a novel p-n junction structure to develop all-oxide UV-vis photodetectors based on stable, nontoxic, low-cost materials.
Published: 2019
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50. Representing dimensions within the reason model of precedent

Author: Adam Rigoni
Subjects: business.industry, Computer science, 05 social sciences, 050109 social psychology, Legal aspects of computing, 06 humanities and the arts, 0603 philosophy, ethics and religion, Artificial intelligence and law, Artificial Intelligence, 0501 psychology and cognitive sciences, Case-based reasoning, 060301 applied ethics, Artificial intelligence, Philosophy of law, business, Law, Mathematical economics, Case base
Abstract: This paper gives an account of dimensions in the reason model found in Horty (Legal Theory 17(1): 1–33, 2011), Horty and Bench-Capon (in: Proceedings of the 15th international conference on artificial intelligence and law, pp 109–118, ACM Press, 2012) and Rigoni (Artif Intell Law 23(2):133–160, 2015. doi: 10.1007/s10506-015-9166-x ). The account is constructed with the purpose of rectifying problems with the approach to incorporating dimensions in Horty (2017), namely, the problems arising from the collapse of the distinction between the reason model and the result model on that approach. Examination of the newly constructed theory revealed that the importance of dimensions in the reason model lies in their ability to establish weighings between reasons/factors of the same polarity. This permits past cases to constrain future cases in ways they could not on the reason model with just factors. The paper then discusses how dimensions might be established from a case base and how dimensions that are incomplete in various aspects might be dealt with in the theory. It closes with comparisons to other work in the literature on AI and Law and suggestions for further improvement of the reason model.
Published: 2017
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