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1. Anastomotic stricture after Ivor Lewis esophagectomy: An evaluation of incidence, risk factors, and treatment

Author

Alexander W. Phillips, Thomas Watkinson, Renol M. Koshy, Jakub Chmelo, and Joshua M. Brown

Subjects
Male, medicine.medical_specialty, Esophageal Neoplasms, medicine.medical_treatment, Constriction, Pathologic, Anastomosis, Esophagus, Postoperative Complications, Quality of life, Refractory, Risk Factors, Surgical Stapling, medicine, Humans, Aged, Retrospective Studies, business.industry, Incidence (epidemiology), Incidence, Anastomosis, Surgical, Odds ratio, Middle Aged, Dilatation, Confidence interval, Surgery, Esophagectomy, Treatment Outcome, Quality of Life, Female, Complication, business
Abstract

Anastomotic stricture is a recognized complication after esophagectomy. It can impact the patient's quality of life and may require recurrent dilatations. Thus, the aim of this study was to evaluate the frequency of strictures, contributing factors, and long-term outcomes of management in patients undergoing esophagectomy with thoracic anastomosis using a standardized circular stapled technique.All patients who underwent a 2-stage transthoracic esophagectomy with curative intent between January 2010 and December 2019 at NOGU, Newcastle upon Tyne, UK were included. All patients who underwent a stapled (circular) intrathoracic anastomosis using gastric conduits were included. Stricture incidence, number of dilatations to resolve strictures, and refractory stricture rate were recorded.Overall, 705 patients were included with 192 (27.2%) developing strictures. Refractory strictures occurred in 38 patients (5.4%). One, 2, and 3 dilatations were needed for resolution of symptoms in 46 (37.4%), 23 (18.7%), and 20 (16.3%) patients, respectively. Multivariable analysis identified the occurrence of an anastomotic leak (odds ratio 1.906, 95% confidence interval 1.088-3.341, P = .024) and circular staple size28 mm (odds ratio 1.462, 95% confidence interval 1.033-2.070, P = .032) as independent predictors of stricture occurrence. Patients with anastomotic leaks were more likely to develop refractory strictures (13.1% vs 4.7%, odds ratio 3.089, 95% confidence interval 1.349-7.077, P = .008).This study highlights that nearly 30% of patients having a circular stapled anastomosis will require dilatation after surgery. Although the majority will completely resolve after 2 dilatations, 5% will have longer-term problems with refractory strictures.

Published
2021

2. WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections

Author

Cristian Mesina, Oussama Baraket, Arda Isik, Iyiade Olaoye, Tadeja Pintar, Wagih Ghnnam, Andreas Hecker, Ionut Negoi, Andrey Litvin, A R K Adesunkanmi, Julival Ribeiro, Stijn W. de Jonge, Norio Sato, Carlos Augusto Gomes, Manos Pikoulis, Federico Coccolini, Yeong Yeh Lee, Frederick A. Moore, Gustavo M. Machain, Francesco Cortese, Elif Colak, Luca Ansaloni, Daniela Corsi, Enrico Cicuttin, Fikri M. Abu-Zidan, Fausto Catena, Andrew W. Kirkpatrick, Raul Coimbra, I. A. Kryvoruchko, Chiara Gurioli, Paola Fugazzola, Gabriele Sganga, András Vereczkei, Sanjay Marwah, Kenji Inaba, Agron Dogjani, Antonio Tarasconi, Elisabetta Cerutti, Rao R. Ivatury, Ibrahima Sall, Michael Sugrue, Francesco M. Labricciosa, Marco Ceresoli, Renol M. Koshy, Jae Il Kim, Goran Augustin, Mauro Podda, Therese M. Duane, Katia Iskandar, Osvaldo Chiara, Dimitris Damaskos, Timothy Craig Hardcastle, Yunfeng Cui, Vishal G Shelat, Joel Noutakdie Tochie, Andrew B. Peitzman, Sameer Dhingra, Miklosh Bala, Ashraf Abbas, Samir Delibegovic, Leonardo Pagani, George Gkiokas, Claudio Casella, Mahir Gachabayov, Gabriel Rodrigues, Stefano Di Bella, Vladimir Khokha, Kemal Rasa, Nicola de’ Angelis, Ernest E. Moore, Robert G. Sawyer, Ronald V. Maier, Yoram Kluger, Ines Rubio-Perez, Victor Y. Kong, Gennaro Perrone, Francesco Di Marzo, Jan Ulrych, Gian Luca Baiocchi, Matti Tolonen, Athanasios Marinis, Cristina Marmorale, G. Tomadze, Peter K. Kim, Belinda De Simone, Aleksandar Karamarkovic, Ian Stephens, Mouaqit Ouadii, Massimo Sartelli, Davide Luppi, Boyko Atanasov, Helmut Alfredo Segovia Lohse, Ervis Agastra, Syed Mohammad Umar Kabir, Massimo Chiarugi, Carlos A. Ordoñez, Giuseppe Pipitone, Bruno Viaggi, Joseph M. Galante, Suman Baral, Ewen A. Griffiths, Mushira Enani, Marja A. Boermeester, Zaza Demetrashvili, Ari Leppäniemi, Torsten Herzog, Walter L. Biffl, Salomone Di Saverio, Sartelli, Massimo, Coccolini, Federico, Kluger, Yoram, Agastra, Ervi, Abu-Zidan, Fikri M, Abbas, Ashraf El Sayed, Ansaloni, Luca, Adesunkanmi, Abdulrashid Kayode, Atanasov, Boyko, Augustin, Goran, Bala, Miklosh, Baraket, Oussama, Baral, Suman, Biffl, Walter L, Boermeester, Marja A, Ceresoli, Marco, Cerutti, Elisabetta, Chiara, Osvaldo, Cicuttin, Enrico, Chiarugi, Massimo, Coimbra, Raul, Colak, Elif, Corsi, Daniela, Cortese, Francesco, Cui, Yunfeng, Damaskos, Dimitri, De' Angelis, Nicola, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, de Jonge, Stijn W, Dhingra, Sameer, Di Bella, Stefano, Di Marzo, Francesco, Di Saverio, Salomone, Dogjani, Agron, Duane, Therese M, Enani, Mushira Abdulaziz, Fugazzola, Paola, Galante, Joseph M, Gachabayov, Mahir, Ghnnam, Wagih, Gkiokas, George, Gomes, Carlos Augusto, Griffiths, Ewen A, Hardcastle, Timothy C, Hecker, Andrea, Herzog, Torsten, Kabir, Syed Mohammad Umar, Karamarkovic, Aleksandar, Khokha, Vladimir, Kim, Peter K, Kim, Jae Il, Kirkpatrick, Andrew W, Kong, Victor, Koshy, Renol M, Kryvoruchko, Igor A, Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao, Labricciosa, Francesco M, Lee, Yeong Yeh, Leppäniemi, Ari, Litvin, Andrey, Luppi, Davide, Machain, Gustavo M, Maier, Ronald V, Marinis, Athanasio, Marmorale, Cristina, Marwah, Sanjay, Mesina, Cristian, Moore, Ernest E, Moore, Frederick A, Negoi, Ionut, Olaoye, Iyiade, Ordoñez, Carlos A, Ouadii, Mouaqit, Peitzman, Andrew B, Perrone, Gennaro, Pikoulis, Mano, Pintar, Tadeja, Pipitone, Giuseppe, Podda, Mauro, Raşa, Kemal, Ribeiro, Julival, Rodrigues, Gabriel, Rubio-Perez, Ine, Sall, Ibrahima, Sato, Norio, Sawyer, Robert G, Segovia Lohse, Helmut, Sganga, Gabriele, Shelat, Vishal G, Stephens, Ian, Sugrue, Michael, Tarasconi, Antonio, Tochie, Joel Noutakdie, Tolonen, Matti, Tomadze, Gia, Ulrych, Jan, Vereczkei, Andra, Viaggi, Bruno, Gurioli, Chiara, Casella, Claudio, Pagani, Leonardo, Baiocchi, Gian Luca, Catena, Fausto, Sartelli, M, Coccolini, F, Kluger, Y, Agastra, E, Abu-Zidan, F, Abbas, A, Ansaloni, L, Adesunkanmi, A, Atanasov, B, Augustin, G, Bala, M, Baraket, O, Baral, S, Biffl, W, Boermeester, M, Ceresoli, M, Cerutti, E, Chiara, O, Cicuttin, E, Chiarugi, M, Coimbra, R, Colak, E, Corsi, D, Cortese, F, Cui, Y, Damaskos, D, de' Angelis, N, Delibegovic, S, Demetrashvili, Z, De Simone, B, de Jonge, S, Dhingra, S, Di Bella, S, Di Marzo, F, Di Saverio, S, Dogjani, A, Duane, T, Enani, M, Fugazzola, P, Galante, J, Gachabayov, M, Ghnnam, W, Gkiokas, G, Gomes, C, Griffiths, E, Hardcastle, T, Hecker, A, Herzog, T, Kabir, S, Karamarkovic, A, Khokha, V, Kim, P, Kim, J, Kirkpatrick, A, Kong, V, Koshy, R, Kryvoruchko, I, Inaba, K, Isik, A, Iskandar, K, Ivatury, R, Labricciosa, F, Lee, Y, Leppaniemi, A, Litvin, A, Luppi, D, Machain, G, Maier, R, Marinis, A, Marmorale, C, Marwah, S, Mesina, C, Moore, E, Moore, F, Negoi, I, Olaoye, I, Ordonez, C, Ouadii, M, Peitzman, A, Perrone, G, Pikoulis, M, Pintar, T, Pipitone, G, Podda, M, Rasa, K, Ribeiro, J, Rodrigues, G, Rubio-Perez, I, Sall, I, Sato, N, Sawyer, R, Segovia Lohse, H, Sganga, G, Shelat, V, Stephens, I, Sugrue, M, Tarasconi, A, Tochie, J, Tolonen, M, Tomadze, G, Ulrych, J, Vereczkei, A, Viaggi, B, Gurioli, C, Casella, C, Pagani, L, Baiocchi, G, Catena, F, HUS Abdominal Center, II kirurgian klinikka, and University of Helsinki

Subjects
Review, DAMAGE CONTROL LAPAROTOMY, Intra-abdominal infections, Peritonitis, Sepsis, Anti-Bacterial Agents, Critical Pathways, Humans, Treatment Outcome, Anti-Infective Agents, Intraabdominal Infections, 0302 clinical medicine, PERFORATED DIVERTICULITIS, Medicine, LAPAROSCOPIC CHOLECYSTECTOMY, Surgical approach, Iais, biology, Peritoniti, Anti-Infective Agents / therapeutic use, Medical emergencies. Critical care. Intensive care. First aid, 3. Good health, SURGICAL-TREATMENT, 030220 oncology & carcinogenesis, embryonic structures, Emergency Medicine, 030211 gastroenterology & hepatology, KLEBSIELLA-PNEUMONIAE, medicine.medical_specialty, RD1-811, Sepsi, MEDLINE, ANTIBIOTIC-THERAPY, 03 medical and health sciences, Intra-abdominal infection, Emergency surgery, Effective treatment, COMPUTED-TOMOGRAPHY, Intensive care medicine, Anti-Bacterial Agents / therapeutic use, Task force, business.industry, RC86-88.9, Abdominal Infection, SEPTIC SHOCK, Intraabdominal Infections / surgery, 3126 Surgery, anesthesiology, intensive care, radiology, biology.organism_classification, Review article, PRIMARY RESECTION, ACUTE COLONIC DIVERTICULITIS, Surgery, business, Intraabdominal Infections / drug therapy
Abstract

Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of effective treatment of IAIs include early recognition, adequate source control, appropriate antimicrobial therapy, and prompt physiologic stabilization using a critical care environment, combined with an optimal surgical approach. Together, the World Society of Emergency Surgery (WSES), the Global Alliance for Infections in Surgery (GAIS), the Surgical Infection Society-Europe (SIS-E), the World Surgical Infection Society (WSIS), and the American Association for the Surgery of Trauma (AAST) have jointly completed an international multi-society document in order to facilitate clinical management of patients with IAIs worldwide building evidence-based clinical pathways for the most common IAIs. An extensive non-systematic review was conducted using the PubMed and MEDLINE databases, limited to the English language. The resulting information was shared by an international task force from 46 countries with different clinical backgrounds. The aim of the document is to promote global standards of care in IAIs providing guidance to clinicians by describing reasonable approaches to the management of IAIs.

Published
2021

3. Safety of nonsteroidal anti-inflammatory drugs in major gastrointestinal surgery: a prospective, multicenter cohort study

Author

Denise Osei-Kuffour, Rahul Bhome, Charn Gill, Oliver Ziff, Ali Bakhsh, Damien Brown, DEVENDER MITTAPALLI, Hayden McRobbie, Dafydd Loughran, Roshni Bhudia, Christopher Graham, John Bassett, Dermot Burke, Guy Stanley, Richard Egan, Michael Stoddart, James Fitzgerald, Thomas Lorchan Lewis, Bryan Traynor, Robert Whitham, Hannah Charlotte Copley, Shaine Morris, Fraser Peck, Chetan Khatri, Rupert Pearse, Christine McGarrigle, Charlotte Holmes, Nicholas Bullock, Adam Boulton, Shyam Gokani, Nicholas John Sebastian Chilvers, Peng Yong Sim, Siyin Liu, Dominic Marshall, Laura Wingfield, Darren Mc Cormack, Angeline Lee, Inge Bernstein, Marie Edison, Babatunde Oremule, Daniel McAuley, STARSurg Collaborative, Joshua Burke, James Glasbey, DR DEVINA MARU, Rebecca Reid, Michael Greshan Rasiah, Ossama Al-Obaedi, Catrin Morgan, Laurie Rigueros Springford, Mary Venn, Sarah Gentry, Chia Yew Kong, Jonathan Wan, Abhishek Chitnis, Nicholas Sim, Justine Davies, Alistair JM Reed, George Bethell, Michael Kelly, Alex Elizabeth Ward, Philip Stather, Shershah Assadullah, Helen Heneghan, Stephen Chapman, Talisa Ross, Renol M Koshy, Paul McEnhill, Alice Buchan, Syed Shumon, Conor Toale, Ewan Kennedy, John Hayes, Amrita Dhutia, Joseph Duncumb, Sarah Hudson-Phillips, Daniyal Jafree, Shujing Jane Lim, Richard Adams, Adam Gwozdz, Kirtan Patel, Olivia Cundy, Richard Moon, Syed Faaz Ashraf, and Claireaux, H

Subjects
Adult, Male, medicine.medical_specialty, law.invention, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Randomized controlled trial, law, Medicine, Humans, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Digestive System Surgical Procedures, Aged, business.industry, Anti-Inflammatory Agents, Non-Steroidal, Odds ratio, Middle Aged, Confidence interval, Colorectal surgery, Surgery, Logistic Models, 030220 oncology & carcinogenesis, Propensity score matching, Female, business, Cohort study, Abdominal surgery
Abstract

Background Significant safety concerns remain surrounding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) following gastrointestinal surgery, leading to wide variation in their use. This study aimed to determine the safety profile of NSAIDs after major gastrointestinal surgery. Methods Consecutive patients undergoing elective or emergency abdominal surgery with a minimum one-night stay during a 3-month study period were eligible for inclusion. The administration of any NSAID within 3 days following surgery was the main independent variable. The primary outcome measure was the 30-day postoperative major complication rate, as defined by the Clavien–Dindo classification (Clavien–Dindo III–V). Propensity matching with multivariable logistic regression was used to produce odds ratios (OR) and 95 % confidence intervals. Results From 9264 patients, 23.9 % (n = 2212) received postoperative NSAIDs. The overall major complication rate was 11.5 % (n = 1067). Following propensity matching and adjustment, use of NSAIDs were not significantly associated with any increase in major complications (OR 0.90, 0.60–1.34, p = 0.560). Conclusions Early use of postoperative NSAIDs was not associated with an increase in major complications following gastrointestinal surgery.

Published
2020

4. Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study

Author

Rahul Bhome, Teo Lopez Bernal, Owen Thorpe, Conor Keogh, Raiyyan Aftab, Muhamed Farhan-Alanie, DEVENDER MITTAPALLI, Aditya Borakati, Roshni Bhudia, Christopher Graham, Vinci Naruka, Dermot Burke, Nicholas Wroe, James Fitzgerald, Matthew Hague, Shaikh Sanjid Seraj, Katie Dunleavy, Emily Greenan, Samira Bell, Hannah Charlotte Copley, Clementina Calabria, Daniel Ahern, Abdul-Rahman Gomaa, Joseph Yates, Chetan Khatri, Martin Connor, Thomas Robert William Ward, Shyam Gokani, Thomas Pinkney, Liam Cato, Edward Balai, Timothy Shao Ern Tan, Sogha Khawari, Peter Coe, Stephen Robinson, STARSurg Collaborative, Joshua Burke, Melika Akhbari, James Glasbey, Nida Ahmed, Jonathan Bannard-Smith, Catrin Morgan, Paul Glen, Laurie Rigueros Springford, Claire Donohoe, Heather Davis, Richard Bogle, Elizabeth Wootton, Mehnoor Khaliq, Sam Myers, Alex Elizabeth Ward, Joanna Osmanska, Jacob King, Oliver Warren, Martin Whyte, Renol M Koshy, Joseph Meredith, Harry VM Spiers, Thomas Ashdown, John Hayes, Hew David Torrance, Dalvir Bajwa, Emanuele Gammeri, Rebecca Spencer, Adam Gwozdz, Kirtan Patel, Jaspreet Kaur Seehra, and Chung Shen Chean

Subjects
medicine.medical_specialty, Surgical stress, business.industry, Mortality rate, Acute kidney injury, Renal function, General Medicine, Odds ratio, medicine.disease, Preoperative care, Surgery, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, 030212 general & internal medicine, Stage (cooking), business, Cohort study
Abstract

Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability.

Published
2018

5. An Unusual Presentation of Gallstone Ileus: A Red-Herring or Missed Diagnosis

Author

Renol M. Koshy, Mohamed A Kurer, Saif Al-Mudares, and Ayman El-Menyar

Subjects
Male, medicine.medical_specialty, Biliary Fistula, Ileus, medicine.medical_treatment, Specialty, Gallstones, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Laparotomy, Gallstone ileus, medicine, Intestinal Fistula, Humans, Aged, business.industry, General surgery, Biliary fistula, General Medicine, Articles, Jejunal Diseases, Hepatology, medicine.disease, Surgery, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Presentation (obstetrics), business, Intestinal Obstruction
Abstract

Patient: Male, 72 Final Diagnosis: Gallstone ileus Symptoms: — Medication: — Clinical Procedure: Laparotomy Specialty: Gastroenterology and Hepatology Objective: Unusual clinical course Background: Gallstone ileus is a rare complication of chronic calcular cholecystitis and an uncommon etiological entity responsible for mechanical intestinal obstruction. The most common obstructed part is the narrow terminal ileum, whereas the jejunum is rarely affected. The gallstone is postulated to reach the small bowel by gradual erosion from the gall bladder, most commonly into the duodenum, forming a cholecysto-duodenal fistula. Case Report: Herein, we report a 72-year-old male who presented with intestinal obstruction of a 5-day duration, with a clinical diagnosis of an irreducible inguinal hernia. However, the patient continued to be symptomatic following an uncomplicated hernioplasty. A computerized tomography (CT) scan of the abdomen revealed a small bowel lesion, which intra-operatively was confirmed to be an impacted gallstone in the jejunum with a cholecysto-duodenal fistula. Conclusions: Despite gallstone is uncommon cause of intestinal obstruction, a high index of suspicion with a careful CT scan interpretation is the key to the diagnosis, especially when there is a red-herring distracting the attention, like irreducible hernia in this case.

Published
2016

6. Correction to: The Operative management in Bariatric Acute abdomen (OBA) Survey: long-term complications of bariatric surgery and the emergency surgeon’s point of view

Author

Y. Cui, M. Radu, Ionut Negoi, G. E. Nita, L. Buonomo, H. Andreas, Eftychios Lostoridis, Francesco Pata, Agron Dogjani, A. Costanzi, R. Villa, F. Piscioneri, F. S. Papadia, T. Bilecik, D. R. Cruz, M. Hutan, D. J. Roberts, G. Bruni, K. Y. Y. Kok, G. Ghilardi, A. Fomin, Bruno M. Pereira, Isidoro Di Carlo, Michael McFarlane, M. Bala, M. Diana, Andrey Litvin, F. Martina, Vladimir Khokha, B. N. Alemu, Cristian Mesina, C. Paolillo, C. Seretis, Arda Isik, Gian Luca Baiocchi, D. Kim, L. Ponchietti, M. Reichert, B. Kessel, K. Lasithiotakisi, Jill R. Cherry-Bukowiec, A. Barberis, Luca Ansaloni, D. Smirnov, Dimitrios K. Manatakis, A. C. Ariffin, A. Dazzi, Renol M. Koshy, F. Karateke, A. Raziel, F. C. Campanile, Massimo Chiarugi, Carlos A. Ordoñez, L. Conti, Marco Ceresoli, Aleix Martínez-Pérez, G. Triantos, N. Michalopoulos, Ramiro Manzano-Nunez, A. Lizarazu, Massimo Sartelli, A. Heyer, R. Sydorchuk, Federico Coccolini, Yoram Kluger, Ioannis Nikolopoulos, V. Calu, Antonio Tarasconi, K. Das, Helmut Alfredo Segovia Lohse, A. Sagnotta, H. van Goor, Ali Guner, S. Maccatrozzo, Fikri M. Abu-Zidan, L. Solaini, T. G. Maurel, Tadeja Pintar, Elif Colak, S. Bonilauri, Victor Y. Kong, S. Gautam, Wagih Ghnnam, V. C. Da Fonseca, Robert G. Sawyer, B. De Simone, D. A. Spain, M. Waledziak, L. Kho, D. Mario, R. Galleano, A. Zaccaroni, Carlos Augusto Gomes, Orestis Ioannidis, C. Arvieux, Zaza Demetrashvili, C. Chatzakis, Piotr Major, Walter L. Biffl, Kuo Ching Yuan, M. Cavalli, D. B. O'Connor, L. Fattori, Mahir Gachabayov, Dimitris Damaskos, G. Campanelli, M. D. Kelly, and Fausto Catena

Subjects
Long term complications, medicine.medical_specialty, business.industry, lcsh:Surgery, lcsh:Medical emergencies. Critical care. Intensive care. First aid, Correction, lcsh:RD1-811, lcsh:RC86-88.9, Surgery, Acute abdomen, Emergency Medicine, medicine, medicine.symptom, business
Abstract

The original article [1] contained an error in authorship whereby author, Fausto Catena was mistakenly listed as part of the institutional authorship of the OBA trial supporters instead of in the correct position of final author.

Published
2020

7. Spontaneous hemoperitoneum, due to bleeding from retroperitoneal varices, in a cirrhotic patient: a case report

Author

Ahmad Abutaka, Abdulrahman Abu Sabeib, Adriana Toro, Renol M. Koshy, and Isidoro Di Carlo

Subjects
medicine.medical_specialty, Cirrhosis, medicine.medical_treatment, Case Report, Case Reports, 03 medical and health sciences, hemorrhagic shock, 0302 clinical medicine, Laparotomy, medicine, Hemoperitoneum, hemoperitoneum, Anamnesis, business.industry, portal hypertension, Cirrhotic patient, varices, General Medicine, medicine.disease, Surgery, 030220 oncology & carcinogenesis, Portal hypertension, 030211 gastroenterology & hepatology, Radiology, Presentation (obstetrics), medicine.symptom, Varices, business
Abstract

Key Clinical Message Hemoperitoneum from retroperitoneal varices in cirrhotic is very rare. This condition should be taken into account based on anamnesis, clinical features, and laboratory findings; but due to the unstable presentation, diagnosis remains a challenge. Emergency laparotomy could be effective treatment, but the prognosis remains poor related to the hepatic reserve.

Published
2015

8. Intraoperative diagnosis of solitary cecal diverticulum not requiring surgery: is appendectomy indicated?

Author

Renol M. Koshy, Saif Al-Mudares, Mohamed Khairat, Abdelrahman Abusabeib, Isidoro Di Carlo, and Adriana Toro

Subjects
medicine.medical_specialty, Iliac fossa, Physical examination, Review, 030230 surgery, Jejunal loop, Resection, 03 medical and health sciences, 0302 clinical medicine, Appendectomy, Medicine, Cecum, medicine.diagnostic_test, business.industry, Diverticulitis, medicine.disease, Appendix, Surgery, Diverticulum, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Emergency Medicine, Cecal Diverticulum, Solitary, business
Abstract

Aim To compare experience with solitary cecal diverticulum (SCD) with literature on the indication for appendectomy in cases of solitary cecal diverticulitis. Methods We retrospectively reviewed all cases of SCD in our institution from September 2011 to March 2013. Data on sex, age, ethnic origin, presence of pain in the right iliac fossa, duration of symptoms, diagnosis, management, intraoperative findings, histologic examination, hospital stay, complications, and follow-up were reviewed and analyzed. We compared this to related literature reported between 2000 and 2015. Results In the study period, 10 patients presented with an SCD. Male sex and Asian origin were predominant. All patients had pain in the right iliac fossa, with a duration of 2–5 days. In nine cases the diagnosis was made by clinical examination and laboratory testing. One patient who had undergone a previous appendectomy was diagnosed with SCD by computed tomography. This last patient was treated conservatively, four patients were treated with resection of the cecum “en bloc” with the last jejunal loop and appendix, and the other five patients were treated with appendectomies. Two patients had minor complications. All patients were followed up for a minimum of 12 to a maximum of 24 months. No recurrence was recorded in either the case treated conservatively or the cases treated by appendectomies. Conclusions In cases of operative but conservative treatment for SCD, appendectomy could be justified to avoid misdiagnosis in case of future episodes of solitary cecal diverticulitis.

Published
2016

9. Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections : a prospective multicentre study (WISS Study)

Author

Elif Colak, Iyiade Olaoye, Raghuveer Mn, Tugan Tezcaner, David W da Costa, Varut Lohsiriwat, Vinod V. Prabhu, Tadeja Pintar, Fausto Catena, Raul Coimbra, Daniel Rios-Cruz, Zaza Demetrashvili, Dimitrios Anyfantakis, Isidoro Di Carlo, John Agboola, Konstantinos Pouggouras, Charalampos Spyropoulos, AA Munyika, Sanjay Marwah, Stefano Rausei, Giovanni Bellanova, Francesco Pata, András Vereczkei, Piotr Major, Nereo Vettoretto, Ari Leppäniemi, Ramakrishnapillai Padmakumar, Geanina Loredana Curca, Oussama Baraket, Marco Catani, Massimo Sartelli, Miguel Leon, Konstantinos Bouliaris, Maria Luisa Sánchez de Molina, Eftychios Lostoridis, Gianfranco Cocorullo, Bandar Alharthi, Ionut Negoi, Zygimantas Kuliesius, Sanjay Gupta, Maurice Zida, Terry Curry, Savas Bayrak, Frederic Branger, Pedro Leão, Teresa Giménez Maurel, Saleh Abdel Kader, Cristian Mesina, Marcelo A. Beltrán, Eudaldo López-Tomassetti Fernandez, Carlos A. Ordoñez, Martin Hutan, Jakub Kenig, Avidyl Krasniqi, Sumita A Jain, Tonguç Utku Yılmaz, Miran Rems, Dmitry Smirnov, Gabrielle H. van Ramshorst, Robin Kaushik, Renato Bessa Melo, Mario Paulo Faro, Ouadii Mouaqit, Asri Che Jusoh, Adamu Amhed, Abdelkarim H. Omari, Jaan Tepp, Ali Guner, Miklosh Bala, Charampolos Seretis, Alain Chichom-Mefire, Nadezda Drozdova, Matej Skrovina, Saila Kauhanen, Aurélien Venara, Aintzane Lizarazu Pérez, Kuo-Ching Yuan, Adesina Ajibade, Silvia Figueiredo Costa, Yoshimitsu Izawa, Mahir Gachabayov, Michael McFarlane, Ricardo Alessandro Teixeira Gonsaga, Ashok Kshirsagar, Jae Gil Lee, Gustavo Pereira Fraga, Koray Das, Jan Ulrych, Tamer El Zalabany, Luca Ansaloni, Victor Y. Kong, Matti Tolonen, Jorge Pereira, Nick Michalopoulos, Georgios Gkiokas, Arda Isik, Orestis Ioannidis, Aleix Martínez-Pérez, Seckin Akkucuk, Giovanni Sinibaldi, Gabriela Elisa Nita, Jae Il Kim, Yunfeng Cui, Federico Coccolini, Ewen A. Griffiths, Roberto Bini, Salomone Di Saverio, Mushira Enani, Boris Sakakushev, Mustafa Yener Uzunoglu, Asrhaf Abbas, Fikri M. Abu-Zidan, David van Dellen, Sandra Gutierrez, Samir Delibegovic, Ioannis Nikolopoulos, Daniele Brunelli, Vishal G Shelat, Ferdinando Agresta, Gerson Alves Pereira Júnior, Goran Augustin, Mantas Jokubauskas, Zeynep Özkan, Sanoop K. Zachariah, Nutu Vlad, Romeo Lages Simões, Konstantinos Lasithiotakis, Giorgio Vasquez, Matthew Boal, Daniele Marrelli, Sanjay Kumar Yadav, Paola Rodriguez Ossa, Vladimir Khokha, Carlos Augusto Gomes, Justas Zilinskas, Gianluca Guercioni, Renol M. Koshy, Gian Luca Baiocchi, Athanasios Marinis, Aleksandar Karamarkovic, Radu Moldovanu, Andrey V. Borodach, Myftar Torba, II kirurgian klinikka, Clinicum, [et al.], Universidade do Minho, Sartelli, M., Abu Zidan, F., Catena, F., Griffiths, E., Di Saverio, S., Coimbra, R., Ordoñez, C., Leppaniemi, A., Fraga, G., Coccolini, F., Agresta, F., Abbas, A., Abdel Kader, S., Agboola, J., Amhed, A., Ajibade, A., Akkucuk, S., Alharthi, B., Anyfantakis, D., Augustin, G., Baiocchi, G., Bala, M., Baraket, O., Bayrak, S., Bellanova, G., Beltràn, M., Bini, R., Boal, M., Borodach, A., Bouliaris, K., Branger, F., Brunelli, D., Catani, M., Che Jusoh, A., Chichom Mefire, A., Cocorullo, G., Colak, E., Costa, D., Costa, S., Cui, Y., Curca, G., Curry, T., Das, K., Delibegovic, S., Demetrashvili, Z., Di Carlo, I., Drozdova, N., El Zalabany, T., Enani, M., Faro, M., Gachabayov, M., Giménez Maurel, T., Gkiokas, G., Gomes, C., Gonsaga, R., Guercioni, G., Guner, A., Gupta, S., Gutierrez, S., Hutan, M., Ioannidis, O., Isik, A., Izawa, Y., Jain, S., Jokubauskas, M., Karamarkovic, A., Kauhanen, S., Kaushik, R., Kenig, J., Khokha, V., Kim, J., Kong, V., Koshy, R., Krasniqi, A., Kshirsagar, A., Kuliesius, Z., Lasithiotakis, K., Leão, P., Lee, J., Leon, M., Lizarazu Pérez, A., Lohsiriwat, V., López Tomassetti Fernandez, E., Lostoridis, E., Mn, R., Major, P., Marinis, A., Marrelli, D., Martinez Perez, A., Marwah, S., Mcfarlane, M., Melo, R., Mesina, C., Michalopoulos, N., Moldovanu, R., Mouaqit, O., Munyika, A., Negoi, I., Nikolopoulos, I., Nita, G., Olaoye, I., Omari, A., Ossa, P., Ozkan, Z., Padmakumar, R., Pata, F., Pereira Junior, G., Pereira, J., Pintar, T., Pouggouras, K., Prabhu, V., Rausei, S., Rems, M., Rios Cruz, D., Sakakushev, B., Sánchez de Molina, M., Seretis, C., Shelat, V., Simões, R., Sinibaldi, G., Skrovina, M., Smirnov, D., Spyropoulos, C., Tepp, J., Tezcaner, T., Tolonen, M., Torba, M., Ulrych, J., Uzunoglu, M., van Dellen, D., van Ramshorst, G., Vasquez, G., Venara, A., Vereczkei, A., Vettoretto, N., Vlad, N., Yadav, S., Yilmaz, T., Yuan, K., Zachariah, S., Zida, M., Zilinskas, J., and Ansaloni, L.

Subjects
medicine.medical_specialty, Infections, Intra-abdominal, Sepsis, Septic shock, Ciências da Saúde [Ciências Médicas], Surgery, Emergency Medicine, Ciências Médicas::Ciências da Saúde, Sepsi, medicine.medical_treatment, macromolecular substances, 030230 surgery, GUIDELINES, Likelihood ratios in diagnostic testing, PERITONITIS, 03 medical and health sciences, PROGNOSTIC-FACTORS, 0302 clinical medicine, Internal medicine, Medicine and Health Sciences, MANAGEMENT, medicine, Intra-abdominal Sepsis, Univariate analysis, Science & Technology, COLONIC PERFORATION, Receiver operating characteristic, business.industry, Abdominal Infection, Immunosuppression, 3126 Surgery, anesthesiology, intensive care, radiology, medicine.disease, 3. Good health, 030220 oncology & carcinogenesis, Infections, Intra-abdominal Sepsis, Observational study, Infection, business, SYSTEM, Research Article
Abstract

BACKGROUND: To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression. ----- METHODS: The WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2 years (range 18-99) were enrolled in the WISS study. ----- RESULTS: Univariate analysis has shown that all factors that were previously included in the WSES Sepsis Severity Score were highly statistically significant between those who died and those who survived (p

Published
2015

10. Triad of post-ERCP pancreatitis, and gastric outlet, and biliary obstruction: are we dealing with intramural duodenal hematoma?

Author

Anil John, Saad Al Kaabi, Ragesh B. Thandassery, and Renol M. Koshy

Subjects
Cholangiopancreatography, Endoscopic Retrograde, Common Bile Duct, medicine.medical_specialty, Hematoma, business.industry, Gastric Outlet Obstruction, General surgery, Gastroenterology, Constriction, Pathologic, Magnetic Resonance Imaging, Surgery, Endosonography, Triad (sociology), Young Adult, Pancreatitis, medicine, Humans, Duodenal hematoma, Female, Duodenal Diseases, Post ercp pancreatitis, business
Published
2014

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