782 results on '"RICKER AS"'
Number of results to display per page
Search Results
2. Punching of edge column–slab connections – comparison of tests and codes
- Author
-
Frank Häusler, Josef Hegger, and Marcus Ricker
- Subjects
Materials science ,Column (typography) ,business.industry ,Slab ,Building and Construction ,Shear reinforcement ,Structural engineering ,Edge (geometry) ,business ,Reinforced concrete ,Punching ,Civil and Structural Engineering - Abstract
To investigate the punching behaviour of edge column–slab connections, 15 tests on full-scale reinforced concrete specimens with and without shear reinforcement are presented. Four slabs were post-tensioned to examine the benefit of curved tendons in the vicinity of edge columns. Besides the discussion of the test results, current code provisions are compared to the ultimate capacities of the present tests as well as tests from the literature. The code provisions are evaluated for reinforced concrete and post-tensioned slabs without shear reinforcement.
- Published
- 2022
- Full Text
- View/download PDF
3. An Exploration into the Creation of ‘Privately Owned Publicly Accessible Spaces’ in Toronto, Ontario
- Author
-
Claire Ricker
- Subjects
Land use ,business.industry ,Process (engineering) ,Exploratory research ,Timeline ,Business ,Public relations ,Space (commercial competition) ,Private sector - Abstract
An exploratory research investigation into the creation of ‘privately owned publicly accessible spaces’ (POPS) in Toronto, Ontario and a critical review of the process used to secure these spaces and the subsequent agreements made. This paper seeks to answer if land use planners are able to better mediate the use of POPS as a means of providing open space to communities in high-density areas. This report includes the timeline illustrating the development of Toronto’s POPS program followed by a discussion on Toronto’s increase growth and development and the suitability of POPS as a contributing strategy for diminishing new park and open space assets and a high level breakdown of the legal mechanisms currently in place to help facilitate new POP spaces. Interviews with individuals from both the public and private sectors were conducted, which produced a generalized model outlining how POPS in Toronto are secured.
- Published
- 2023
- Full Text
- View/download PDF
4. Optimal sleep and circadian habits in infants and children
- Author
-
Ashley A. Ricker, Lauren E. Hartstein, Sachi D. Wong, and Monique K. LeBourgeois
- Subjects
medicine.medical_specialty ,business.industry ,medicine ,Circadian rhythm ,Audiology ,business ,Sleep in non-human animals - Published
- 2023
- Full Text
- View/download PDF
5. Trends in opioid use following balloon kyphoplasty or vertebroplasty for the treatment of vertebral compression fractures
- Author
-
M Quinn, W Ni, C J Gilligan, N Gasquet, D Janardhanan, C Ricker, and Joshua A Hirsch
- Subjects
Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Population ,Balloon ,Internal medicine ,Fractures, Compression ,medicine ,Humans ,Kyphoplasty ,Medical prescription ,education ,Aged ,Retrospective Studies ,Vertebroplasty ,education.field_of_study ,business.industry ,Vertebral compression fracture ,medicine.disease ,Rheumatology ,Surgery ,Analgesics, Opioid ,Treatment Outcome ,Opioid ,Orthopedic surgery ,Spinal Fractures ,Population study ,Female ,business ,Osteoporotic Fractures ,medicine.drug - Abstract
This retrospective analysis of insurance claims evaluated real-world trends in prescription fills among patients treated with balloon kyphoplasty (N = 6,656) or vertebroplasty (N = 2,189) following diagnosis of vertebral compression fracture. Among those with evidence of opioid use, nearly half of patients discontinued or reduced prescription fills relative to pre-operative levels. Vertebral compression fractures (VCF) are associated with debilitating pain, spinal misalignment, increased mortality, and increased healthcare-resource utilization in elderly patients. This study evaluated the effect of balloon kyphoplasty (BKP) or vertebroplasty (VP) on post-procedure opioid prescription fills and payer costs in patients with VCF. This was a retrospective analysis of a large, nationally representative insurance-claims database. Clinical characteristics, opioid prescription patterns, and payer costs for subjects who underwent either BKP or VP to treat VCF were evaluated beginning 6 months prior to surgery through 7-month follow-up that included a 30-day, postoperative medication washout. Patient demographics, changes in opioid utilization, and payer costs were analyzed. A total of 8,845 patients met eligibility criteria (75.3% BKP and 24.7% VP) with a mean of age 77 and 74% female. Among the 75% of patients who used opioids, 48.7% of patients discontinued opioid medication and 8.4% reduced prescription fills versus preoperative baseline. Patients who reduced or discontinued prescriptions exhibited a decrease in all-cause payer costs relative to pre-intervention levels, which was a significantly greater change relative to patients with no change, increase, or new start of opioids. Interventional treatment for VCF was associated with decreased or discontinued opioid prescription fills and reduced payer costs in follow-up in a significant proportion of the study population. Reduction of opioid-based harms may represent a previously unrecognized benefit of vertebral augmentation for VCF, especially in this elderly and medically fragile population.
- Published
- 2021
- Full Text
- View/download PDF
6. Stochastic approach for the material properties of reinforcing textiles for the design of concrete members
- Author
-
Tânia Feiri, Marcus Ricker, and Sergej Rempel
- Subjects
Multidisciplinary ,Textile ,business.industry ,Computer science ,Science ,Statistics ,Young's modulus ,Structural engineering ,Epoxy ,Structural materials ,Article ,symbols.namesake ,Gumbel distribution ,visual_art ,Ultimate tensile strength ,symbols ,visual_art.visual_art_medium ,Medicine ,Civil engineering ,Reinforcement ,business ,Material properties ,Tensile testing - Abstract
Textile-reinforced concrete has emerged in recent years as a new and valuable construction material. The design of textile-reinforced concrete requires knowledge on the mechanical properties of different textile types as well as their reinforcing behaviour under different loading conditions. Conventional load-bearing tests tend to be complex, time-consuming, costly and can even lack consistent specifications. To mitigate such drawbacks, a standardised tensile test for fibre strands was used to characterise the material properties needed for the design of a textile-reinforced concrete member. The standardised tensile test uses a fibre strand with 160 mm length, which is cut out of a textile grid. For the sake of this study, an epoxy resin-soaked AR-glass reinforcement was considered. The results show that the textile reinforcement has a linear-elastic behaviour, and the ultimate tensile strength can be statistically modelled by a Gumbel distribution. Furthermore, the results indicate that the modulus of elasticity is not influenced by the length or the number of fibre strands. Therefore, the mean value attained from the standardised test can be used for design purposes. These findings are essential to derive an appropriate partial safety factor for the calculation of the design values of the tensile strength and can be used to determine the failure probability of textile-reinforced concrete members.
- Published
- 2021
7. Soil Investments on Rented versus Owned Plots: Evidence from a Matched Tenant-Landlord Sample in Malawi
- Author
-
Jacob Ricker-Gilbert, Jordan Chamberlin, and Joseph Kanyamuka
- Subjects
Economics and Econometrics ,Agricultural science ,Sample (statistics) ,Business ,Landlord ,Environmental Science (miscellaneous) - Published
- 2021
- Full Text
- View/download PDF
8. Absentee tenants and farmland transfers in sub-Saharan Africa: evidence from Malawi
- Author
-
Jordan Chamberlin, Jacob Ricker-Gilbert, and Thomas S. Jayne
- Subjects
Economic growth ,Sub saharan ,Geography, Planning and Development ,Landlord ,Business ,Development - Abstract
This is the accepted manuscript version of the work published in its final form as Ricker-Gilbert, Jacob;Jayne, T. S.;Chamberlin, Jordan. JDevelopment in Practice, page(s): 1–19.https://www.tandfonline.com/10.1080/09614524.2021.1937567 Deposited byshareyourpaper.organdopenaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailinghelp@openaccessbutton.org.
- Published
- 2021
- Full Text
- View/download PDF
9. Narrative frames as choice over structure of American Indian sexual and reproductive health consequences of historical trauma
- Author
-
Paula FireMoon, Michael Anastario, Adriann Ricker, Genevieve R. Cox, and Elizabeth Rink
- Subjects
Health (social science) ,Historical trauma ,business.industry ,Health Policy ,education ,Public Health, Environmental and Occupational Health ,Community-based participatory research ,Gender studies ,Context (language use) ,Historical Trauma ,Colonialism ,Structural violence ,Article ,humanities ,Reproductive Health ,Framing (social sciences) ,Indians, North American ,Humans ,Narrative ,Internalized oppression ,Sociology ,business ,American Indian or Alaska Native ,Reproductive health - Abstract
Emerging evidence suggests that the historical trauma associated with settler colonialism affects the sexual and reproductive health (SRH) of American Indian (AI) communities today. This article examines how one AI community narratively frames the influence of historical trauma within the context of community-based participatory research (CBPR) and the implications of this framing for health behaviours, internalized oppression, SRH outcomes, and future CBPR interventions. We found that AIs framed the SRH consequences of historical trauma with renderings that favoured personal choice over structural explanations. Our findings suggest future interventions could: (1) include educational components on historical trauma and the continued role settler colonialism plays in structural violence against AI bodies and communities; and (2) recognize the role that the individualized logic of westernized/white culture may play in the erasure of traditional collectivist AI culture, internalized oppression, and SRH.
- Published
- 2021
- Full Text
- View/download PDF
10. Willingness to pay for a new farm technology given risk preferences: Evidence from an experimental auction in Kenya
- Author
-
Jacob Ricker-Gilbert, Hugo De Groote, Hira Channa, and Jonathan Bauchet
- Subjects
Economics and Econometrics ,Agricultural science ,Willingness to pay ,business.industry ,Moisture measurement ,Common value auction ,Food safety ,business ,Agronomy and Crop Science ,Framing effect - Abstract
Smallholder farmers and small‐scale traders who do not have access to moisture measurement tools may not be able to fully observe moisture content in their grain. However, encouraging the adoption of these tools is important for food safety, because growth of dangerous toxins can be prevented by drying grain to 13.5% moisture content or below before storage. Several low‐cost devices have recently been developed that can accurately test moisture content in maize. In this article, we first estimate the demand for two such devices among smallholder farmers and small‐scale traders in Western Kenya. Second, we measure the impact of individuals’ risk aversion on willingness to pay for these devices. Third, we measure framing effects in experimental auctions by eliciting valuations with increasing and decreasing price lists. We found that more than 80% of respondents were willing to pay more than the wholesale price for the cheaper of the two devices. Farmers in our sample, who were growing maize primarily for own consumption, were willing to pay more than traders. Individuals who were more risk‐averse reported a slightly higher willingness‐to‐pay for these risk‐reducing devices. Finally, farmers—but not traders—were sensitive to framing effects: mean bids elicited with a decreasing price list during the auction were 37% higher than those with an increasing price list.
- Published
- 2021
- Full Text
- View/download PDF
11. Randomised controlled trial of the effects of increased energy intake on menstrual recovery in exercising women with menstrual disturbances: the ‘REFUEL’ study
- Author
-
Jennifer L. Scheid, Prabhani Kuruppumullage Don, Mary Jane De Souza, Daniel J. Mallinson, Heather C.M. Allaway, Emily A Ricker, Nancy I. Williams, Rebecca J. Mallinson, Nicole C.A. Strock, Kristen J. Koltun, and Marion P. Olmsted
- Subjects
Adult ,Female athlete triad ,medicine.medical_specialty ,media_common.quotation_subject ,law.invention ,Menstruation ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Humans ,Medicine ,Amen ,Exercise ,Menstruation Disturbances ,Menstrual cycle ,media_common ,030219 obstetrics & reproductive medicine ,business.industry ,Rehabilitation ,Hazard ratio ,Obstetrics and Gynecology ,General Medicine ,Original Articles ,030229 sport sciences ,medicine.disease ,United States ,Oligomenorrhea ,Eating disorders ,Reproductive Medicine ,Physical therapy ,Female ,Amenorrhea ,medicine.symptom ,Energy Intake ,business - Abstract
STUDY QUESTION Does increased daily energy intake lead to menstrual recovery in exercising women with oligomenorrhoea (Oligo) or amenorrhoea (Amen)? SUMMARY ANSWER A modest increase in daily energy intake (330 ± 65 kcal/day; 18 ± 4%) is sufficient to induce menstrual recovery in exercising women with Oligo/Amen. WHAT IS KNOWN ALREADY Optimal energy availability is critical for normal reproductive function, but the magnitude of increased energy intake necessary for menstrual recovery in exercising women, along with the associated metabolic changes, is not known. STUDY DESIGN, SIZE, DURATION The REFUEL study (trial # NCT00392873) is the first randomised controlled trial to assess the effectiveness of 12 months of increased energy intake on menstrual function in 76 exercising women with menstrual disturbances. Participants were randomised (block method) to increase energy intake 20–40% above baseline energy needs (Oligo/Amen + Cal, n = 40) or maintain energy intake (Oligo/Amen Control, n = 36). The study was performed from 2006 to 2014. PARTICIPANTS/MATERIALS, SETTING, METHODS Participants were Amen and Oligo exercising women (age = 21.0 ± 0.3 years, BMI = 20.8 ± 0.2 kg/m2, body fat = 24.7 ± 0.6%) recruited from two universities. Detailed assessment of menstrual function was performed using logs and measures of daily urinary ovarian steroids. Body composition and metabolic outcomes were assessed every 3 months. MAIN RESULTS AND THE ROLE OF CHANCE Using an intent-to-treat analysis, the Oligo/Amen + Cal group was more likely to experience menses during the intervention than the Oligo/Amen Control group (P = 0.002; hazard ratio [CI] = 1.91 [1.27, 2.89]). In the intent-to-treat analysis, the Oligo/Amen + Cal group demonstrated a greater increase in energy intake, body weight, percent body fat and total triiodothyronine (TT3) compared to the Oligo/Amen Control group (P LIMITATIONS, REASONS FOR CAUTION While we had a greater than expected dropout rate for the 12-month intervention, it was comparable to other shorter interventions of 3–6 months in duration. Menstrual recovery defined herein does not account for quality of recovery. WIDER IMPLICATIONS OF THE FINDINGS Expanding upon findings in shorter, non-randomised studies, a modest increase in daily energy intake (330 ± 65 kcal/day; 18 ± 4%) is sufficient to induce menstrual recovery in exercising women with Oligo/Amen. Improved metabolism, as demonstrated by a modest increase in body weight (4.9%), percent body fat (13%) and TT3 (16%), was associated with menstrual recovery. STUDY FUNDING/COMPETING INTEREST(S) This research was supported by the U.S. Department of Defense: U.S. Army Medical Research and Material Command (Grant PR054531). Additional research assistance provided by the Penn State Clinical Research Center was supported by the National Center for Advancing Translation Sciences, National Institutes of Health, through Grant UL1 TR002014. M.P.O. was supported in part by the Loretta Anne Rogers Chair in Eating Disorders at University of Toronto and University Health Network. All authors report no conflict of interest. TRIAL REGISTRATION NUMBER NCT00392873 TRIAL REGISTRATION DATE October 2006 DATE OF FIRST PATIENT’S ENROLMENT September 2006
- Published
- 2021
- Full Text
- View/download PDF
12. Open data from the first and second observing runs of advanced LIGO and advanced Virgo
- Author
-
Rich , Abbott, Thomas , Sheelu , Abraham, Fausto , Acernese, Kendall , Ackley, Carl , Adams, Rana , Adhikari, Vaishali , Adya, Christoph , Affeldt, Michalis , Agathos, Kazuhiro , Agatsuma, Nancy , Aggarwal, Odylio , Aguiar, Amit , Aich, Lorenzo , Aiello, Anirban , Ain, Ajith , Parameswaran, Gabrielle , Allen, Annalisa , Allocca, Paul , Altin, Alex , Amato, Shreya , Anand, Alena , Ananyeva, Stuart , Anderson, Warren , Svetoslava, Angelova, Stefano , Ansoldi, Sarah , Antier, Stephen , Appert, Koji , Arai, Melody, Araya, Joseph, Areeda, Marc , Arène, Nicolas , Arnaud, Scott, Aronson, Arun, Kg, Ascenzi, Gregory , Ashton, Stuart, Aston, Pia , Astone, Florian , Aubin, Peter , Aufmuth, Kellie , Aultoneal, Corey , Austin, Valerie , Avendano, Stanislav , Babak, Philippe , Bacon, Francesca , Badaracco, Maria, Bader, Sangwook , Bae, Anne, Baer, Jonathon , Baird, Baldaccini, Giulio , Ballardin, Stefan, Ballmer, Anna-marie , Bals, Alexander , Balsamo, Baltus, Sharan , Banagiri, Deepak , Bankar, Rameshwar, Bankar, Juan, Barayoga, Claudio , Barbieri, Barry, Barish, David , Barker, Kevin , Barkett, Pablo , Barneo, Fabrizio , Barone, Bryan , Barr, Lisa , Barsotti, Matteo , Barsuglia, Daniel , Barta, Jeffrey , Bartlett, Imre , Bartos, Riccardo , Bassiri, Andrea , Basti, Mateusz , Bawaj, Joseph, Bayley, Marco , Bazzan, Bence , Bécsy, Michal , Bejger, Imene , Belahcene, Angus, Bell, Deeksha , Beniwal, Michael, Benjamin, Joe, Bentley, Fabio , Bergamin, Beverly, Berger, Gerald , Bergmann, Sebastiano , Bernuzzi, Christopher, Berry, Diego , Bersanetti, Alessandro , Bertolini, Joseph , Betzwieser, Rohan , Bhandare, Ankit, Bhandari, Bidler, Edward , Biggs, Igor, Bilenko, Garilynn , Billingsley, Ross , Birney, Ofek , Birnholtz, Sebastien , Biscans, Bischi, Sylvia , Biscoveanu, Aparna , Bisht, Guldauren , Bissenbayeva, Massimiliano , Bitossi, Marieanne, Bizouard, Kent, Blackburn, Jonathan , Blackman, Carl, Blair, David, Blair, Ryan, Blair, Bobba, Nina , Bode, Michel , Boer, Yannick , Boetzel, Gilles , Bogaert, Francois , Bondu, Edgard , Bonilla, Romain , Bonnand, Phillip , Booker, Boris, Boom, Rolf , Bork, Valerio , Boschi, Sukanta , Bose, Vladimir , Bossilkov, Joel , Bosveld, Yann , Bouffanais, Antonella , Bozzi, Carlo , Bradaschia, Patrick, Brady, Alyssa , Bramley, Marica , Branchesi, Jim, Brau, Breschi, Tristan , Briant, Joseph, Briggs, Francesco , Brighenti, Alain , Brillet, Brinkmann, Patrick , Brockill, Aidan, Brooks, Brooks, Daniel, Brown, Sharon , Brunett, Giacomo , Bruno, Robert , Bruntz, Aaron , Buikema, Tomasz , Bulik, Henk, Bulten, Alessandra , Buonanno, Damir , Buskulic, Robert, Byer, Miriam , Cabero, Laura , Cadonati, Giampietro , Cagnoli, Craig , Cahillane, Juan , Calderón , Bustillo, Jack, Callaghan, Thomas, Callister, Enrico , Calloni, Jordan, Camp, Maurizio , Canepa, Kipp, Cannon, Huy-tuong , Cao, Junwei , Giovanni , Carapella, Franco , Carbognani, Santiago , Caride, Matthew, Carney, Gregorio , Carullo, Julia , Casanueva , Diaz, Claudio , Casentini, Javier , Castañeda, Sarah , Caudill, Marco , Cavaglià, Fabien , Cavalier, Roberto , Cavalieri, Giancarlo , Cella, Pablo , Cerdá-Durán, Elisabetta , Cesarini, Oualid , Chaibi, Kabir , Chakravarti, Chiwai , Chan, Manleong , Chan, Shiuh , Chao, Philip , Charlton, Eve, Chase, Eric , Chassande-Mottin, Deep , Chatterjee, Mayank , Chaturvedi, Hsin-yu, Chen, Xu , Chen, Yanbei , Hai-ping , Cheng, Chi-kit, Cheong, Hanyu, Chia, Chiadini, Roberto , Chierici, Chincarini, Antonino , Chiummo, Gihyuk , Cho, Heesuk, Cho, Min-a , Nelson , Christensen, Qi , Chu, Sheon , Chua, Ka-wai, Chung, Shinkee , Chung, Ciani, Pawel , Ciecielag, Marek , Cieślar, Alexei, Ciobanu, Ciolfi, Cipriano, Alessio , Cirone, Filiberto , Clara, James, Clark, Clearwater, Clesse, Frederic , Cleva, Eugenio , Coccia, Pierre-francois , Cohadon, Cohen, Marta , Colleoni, Christophe, Collette, Christopher , Collins, Monica , Colpi, Marcio , Constancio , Livia , Jr., Conti, Sam, Cooper, Corban, Thomas, Corbitt, Isabel , Cordero-Carrión, Silvia , Corezzi, Kenneth, Corley, Neil , Cornish, Corre, Corsi, Cortese, Cesar, Costa, Cotesta, Michael, Coughlin, Scott, Coughlin, Jeanpierre , Coulon, Stefan, Countryman, Couvares, Pep, Covas, David, Coward, Matthew, Cowart, Dennis, Coyne, Coyne, Jolien,  , Creighton, Teviet, Creighton, Cripe, Michael , Croquette, Sgwynne, Crowder, Jean-rene , Cudell, Torrey, Cullen, Alan , Cumming, Rebecca , Cummings, Liam , Cunningham, Elena , Cuoco, Malgorzata , Curylo, Tito , Dal , Canton, Gergely , Dálya, Aykutlu , Dana, Lara, Daneshgaran-Bajastani, Beatrice , D’Angelo, Stefan, Danilishin, Sabrina , D’Antonio, Karsten , Danzmann, Christian , Darsow-Fromm, Arnab , Dasgupta, Laurence,  , Datrier, Vincenzo , Dattilo, Ishant , Dave, Michel , Davier, Gareth, Davies, Derek , Davis, Edward, Daw, Dan , Debra, Malathi , Deenadayalan, Jerome , Degallaix, Martina , De , Laurentis, Samuel , Deléglise, Matthew , Delfavero, Nicola , Lillo, Walter , Del , Pozzo, Lindsay, Demarchi, Virginia , D’Emilio, Nicholas , Demos, Dent, Pietri, Rosario , Rosa, Camilla , Rossi, Riccardo , Desalvo, Omar , de , Varona, Sanjeev , Dhurandhar, Mario, Díaz, Mauricio , Diaz-Ortiz , Tim , Dietrich, Luciano , Di , Fiore, Chiara , Fronzo, Cinzia , Giorgio, Giovanni, Matteo , Giovanni, Tristano , Girolamo, Alberto , Lieto, Binlei , Ding, Sibilla , Pace, Irene , Palma, Renzo, Atul, Divakarla, Artemiy , Dmitriev, Zoheyr , Doctor, Fred , Donovan, Katherine, Dooley, Suresh , Doravari, Iain , Dorrington, Thomas, Downes, Drago, Jenne, Driggers, Zhihui , Jean-gregoire , Ducoin, Dupej, Ofelia , Durante, Domenico , D’Urso, Sheila, Dwyer, Paul, Easter, Graeme , Eddolls, Bruce , Edelman, Tega, Edo, Oliver , Edy, Anamaria , Effler, Phil , Ehrens, Johannes , Eichholz, Stephen, Eikenberry, Eisenmann, Robert, Eisenstein, Aldo , Ejlli, Lucianolucianikerrico , Errico, Reed, Essick, Hector , Estelles, Dimitri , Estevez, Zachariah, Etienne, Todd , Etzel, Matthew , Evans, Tom, Evans, Rebecca, Ewing, Viviana , Fafone, Fairhurst, Xilong , Fan, Stefania , Farinon, Benjamin , Farr, Will, Farr, Edward, Fauchon-Jones, Favata, Maxime , Fays, Mariana , Fazio, Jon , Feicht, Martin, Fejer, Fangchen , Feng, Edit , Fenyvesi, Deborah, Ferguson, Alvaro , Fernandez-Galiana, Isidoro , Ferrante, Elvis, Ferreira, Tabata, Ferreira, Fidecaro, Irene , Fiori, Donatella , Fiorucci, Maya , Fishbach, Ryan, Fisher, Rosalba , Fittipaldi, Margot , Fitz-Axen, Vincenzo , Fiumara, Raffaele , Flaminio, Erik , Floden, Flynn, Heather , Fong, Antonio, Font, Perry , Forsyth, Jean-daniel , Fournier, Sergio , Frasca, Frasconi, Zsolt , Frei, Andreas , Freise, Raymond , Frey, Valentin , Fritschel, Valery, Frolov, Gabriele , Fronzè, Fulda, Fyffe, Hunter, Gabbard, Bhooshan, Gadre, Sebastian, Gaebel, Jonathan, Gair, Shanika , Galaudage, Dhruva , Ganapathy, Sharad, Gaonkar, Cecilio , García-Quirós, Garufi, Bubba , Gateley, Gaudio, Gayathri , Gayathri, Gianluca , Gemme, Genin, Alberto , Gennai, George, Jogy , Laszlo , Gergely, Sudarshan , Ghonge, Abhirup , Ghosh, Archisman , Shaon , Bruno , Giacomazzo, Joe, Giaime, Dwayne, Giardina, Des, Gibson, Chalisa , Gier, Kiranjyot , Gill, Jane , Glanzer, Jan , Gniesmer, Godwin, Evan , Goetz, Ryan , Niklas , Gohlke, Boris , Goncharov, Gabriela , González, Gopakumar , Gopakumar, Sarah, Gossan, Matthieu , Gosselin, Gouaty, Grace, Aniello , Grado, Massimo , Granata, Alastair , Grant, Slawomir , Gras, Grassia, Gray, Rachel , Giuseppe , Greco, Anna, Green, Rhys , Green, Elizabeth, Gretarsson, Hannah, Griggs, nbsp, Grignani, Grimaldi, Stefan, Grimm, Hartmut , Grote, Steffen , Grunewald, Pierre , Gruning, Gianluca, Guidi, Andre, Guimaraes, Gerard , Guixé, Hitesh, Gulati, Yuefan , Guo, Anuradha , Gupta, Anchal , Pawan , Eric, Gustafson, Dick , Gustafson, Leila , Haegel, Odysse , Halim, Evan, Hall, Eleanor, Hamilton, Giles , Hammond, Maria , Haney, Manuela, Hanke, Hanks, Chad , Hanna, Mark, Hannam, Otto, Hannuksela, Travis, Hansen, Joe , Hanson, Harder, Terra , Hardwick, Haris , Haris, Harms, Gregg, Harry, Ian, Harry, Raine, Hasskew, Carl-johan , Haster, Karen , Haughian, Fergus, Hayes, James , Healy, Antoine , Heidmann, Matthew, Heintze, Joscha , Heinze, Henrich , Heitmann, Frances , Hellman, Patrice , Hello, Gary , Hemming, Martin , Hendry, Siong, Heng, Hennes, Jan-simon , Hennig, Michele , Heurs, Stefan , Hild, Tanja , Hinderer, Sarah, Hoback, Sven , Hochheim, Elyssa , Hofgard, Hofman, Aaron, Holgado, Nathan, Holland, Kathy , Holt, Daniel, Holz, Hopkins, Horst, Hough, Eric, Howell, Charlie, Hoy, Yiwen , Huang, Moritz, Hübner, Eliu, Huerta, Dominique , Huet, Brennan , Hughey, Victor , Hui, Sascha , Husa, Sabina, Huttner, Rachael , Huxford, Tien , Huynh-Dinh, Bartosz , Idzkowski, Iess, Henri , Inchauspe, Ingram, Intini, Jean, Isac, Max , Isi, Bala, Iyer, Thibaut , Jacqmin, Sameer, Jadhav, Shreejit, Jadhav, Alasdair, James, Karan , Jani, Nagaraj, Janthalur, Piotr , Jaranowski, Jariwala, Rafel , Jaume, Alex, Jenkins, Jun , Jiang, Grace, Johns, Aaron, Jones, Ian, Jones, Jeff, Jones, Philip , Jones, Russell , Reinier,  , Jonker, Ju , Jonas , Junker, Chinmay, Kalaghatgi, Vassiliki , Kalogera, Brittany , Kamai, Shivaraj , Kandhasamy, Gungwon , Kang, Jonah, Kanner, Shasvath, Kapadia, Karki, Rahul , Kashyap, Marie , Kasprzack, Wolfgang , Kastaun, Stavros , Katsanevas, Katsavounidis, William , Katzman, Kaufer, Keita , Kawabe, Fabien , Kéfélian, Keitel, Azadeh , Keivani, Kennedy, Joey, Key, Sudiksha , Khadka, Farit, Khalili, Imran , Khan, Sebastian , Zaki, Khan, Efim, Khazanov, Nandita , Khetan, Mohammad , Khursheed, Nutsinee , Kijbunchoo, Chunglee , Kim, Grace, Kim, Jeongcho, Kim, Kyungmin , Won , Whansun, Kim, Young-min , Charles , Kimball, Peter, King, Kinley-Hanlon, Robin , Kirchhoff, Jeffrey, Kissel, Kleybolte, Sergei , Klimenko, Tyler, Knowles, Koch, Sina, Koehlenbeck, Gideon , Koekoek, Soumen , Koley, Veronica , Kondrashov, Antonios , Kontos, Nico , Koper, Mikhail , Korobko, William, Korth, Manoj , Kovalam, Dan, Kozak, Volker , Kringel, Krishnendu, Nv, Andrzej , Królak, Natalie , Krupinski, Gerrit , Kuehn, Anil , Kumar, Prayush , Rakesh , Sumit , Ling-chi , Kuo, Adam , Kutynia, Benjamin, Lackey, Danny , Laghi, Emile , Lalande, Lam, Lam, Astrid , Lamberts, Landry, Benjamin, Lane, Ryan, Lang, Jacob , Lange, Brian , Lantz, Robert, Lanza, Iuri , La , Rosa, Angelique , Lartaux-Vollard, Paul, Lasky, Laxen, Albert , Lazzarini, Claudia , Lazzaro, Paola , Leaci, Sean , Leavey, Yannick, Lecoeuche, Chang-hwan, Lee, Hyung-mok, Lee, Hyungwon, Lee, Joongoo , Lee, Kyung-ha , Lehmann, Leroy, Letendre, Yuri , Levin, Alvin,  , Jin , Kaye , Tjonnie,  , Xiang , Frank , Linde, Seth, Linker, Jethro, Linley, Tyson, Littenberg, Liu , Liu, Xiaoshu , Miquel , Llorens-Monteagudo, Ka-lok , Alexandra , Lockwood, Lionel, London, Longo, Lorenzini, Vincent , Loriette, Lormand, Losurdo, James, Lough, Carlos, Lousto, Geoffrey , Lovelace, Harald , Lück, Diana , Lumaca, Andrew, Lundgren, Ma , Yiqiu, Ronaldas , Macas, Macfoy, Myron , Macinnis, Duncan, Macleod, Ian, Macmillan, Adrian , Macquet, Ignacio , Magaña , Hernandez, Fabian , Magaña-Sandoval, Ryan, Magee, Ettore , Majorana, Ivan , Maksimovic, Asmita , Malik, Catherine , Man, Vuk , Mandic, Valentina , Mangano, Georgia, Mansell, Manske, Maddalena , Mantovani, Michela , Mapelli, Marchesoni, Frederique , Marion, Szabolcs , Márka, Zsuzsanna , Charalampos , Markakis, Ashot, Markosyan, Markowitz, Ed , Maros, Antonio , Marquina, Sylvain , Marsat, Filippo , Martelli, Ian, Martin, Rodica, Martin, Martinez, Denis, Martynov, Hossein , Masalehdan, Ken , Mason, Massera, Masserot, Thomas, Massinger, Mariela , Masso-Reid, Simone , Mastrogiovanni, Andrew , Matas, Fabrice , Matichard, Nergis , Mavalvala, Emily , Maynard, Joshua, Mccann, Richard , Mccarthy, David, Mcclelland, Scott , Mccormick, Lee , Mcculler, Stephen, Mcguire, Connor , Mcisaac, Jessica , Mciver, David, Mcmanus, Terry , Mcrae, Sean, Mcwilliams, Duncan , Meacher, Grant, Meadors, Moritz , Mehmet, Ajit, Mehta, Mejuto , Villa, Andrew , Melatos, Gregory , Mendell, Adam, Mercer, Mereni, Kara , Merfeld, Edmond, Merilh, Jonathan, Merritt, Mourad , Merzougui, Syd , Meshkov, Chris , Messenger, Cody , Messick, Remi , Metzdorff, Patrick, Meyers, Fabian , Meylahn, Ashish , Mhaske, Miani, Haixing , Miao, Ioannis , Michaloliakos, Christophe , Michel, Hannah , Middleton, Leopoldo , Milano, Andrewlawrence, Miller, Meg , Millhouse, Joseph, Mills, Edoardo , Milotti, Michael, Milovich-Goff, Olivier , Minazzoli, Minenkov, Alec , Mishkin, Chandra , Mishra, Timesh , Mistry, Sanjit , Mitra, Valery, Mitrofanov, Guenakh , Mitselmakher, Mittleman, Kentaro , Mogushi, Satyanarayan,  , Mohapatra, Siddharth, Mohite, Manel , Molina-Ruiz, Marina , Mondin, Montani, Christopher, Moore, Moraru, Filip , Morawski, Gerardo , Moreno, Soichiro , Morisaki, Benoit , Mours, Conor, Mow-Lowry, Mozzon, Federico , Muciaccia, Arunava , Mukherjee, Debnandini , Soma , Subroto , Nikhil , Mukund, Mullavey, Jesper , Munch, Erik, Muñiz, Peter, Murray, Nagar, Ilaria , Nardecchia, Luca , Naticchioni, Rajesh, Nayak, Benjamin, Neil, Joshua , Neilson, Gijs , Nelemans, Timothy,  , Nelson, Marina , Nery, Ansel , Neunzert, Kwan-yeung, Ng, Nguyen, Nichols, Shania, Nichols, Samaya , Nissanke, Flavio , Nocera, Minkyun , Noh, North, Devon , Nothard, Laura, Nuttall, Jason , Oberling, Brendan, O’Brien, Gor , Oganesyan, Greg, Ogin, John, Oh, Sanghoon, Oh, Ohme, Hiroaki , Ohta, Marcos, Okada, Oliver, Olivetto, Oppermann, Oram, O’Reilly, Rich, Ormiston, Luis, Ortega, O’Shaughnessy, Serguei , Ossokine, Osthelder, David, Ottaway, Harry , Overmier, Ben, Owen, Alexander, Pace, Giulia , Pagano, Michael, Page, Pagliaroli, Archana , Pai, Siddhesh, Pai, Jordan, Palamos, Oleg , Palashov, Cristiano , Palomba, Howard , Pan, Pratap, Panda, Tsun-ho , Pang, Pankow, Pannarale, F, Brijesh, Pant, Paoletti, Paoli, Abhishek , Parida, Parker, Daniela , Pascucci, Pasqualetti, Passaquieti, Passuello, Barbara , Patricelli, Ethan , Payne, Brynley, Pearlstone, Thida, Pechsiri, Ari, Pedersen, Mike , Pedraza, Arnaud , Pele, Steven , Penn, Albino , Perego, Carlos, Perez, Perigois , Périgois, Perreca, Stephane , Perriès, Petermann, Harald, Pfeiffer, Phelps, Khun, Phukon, Ornella, Piccinni, Mikhael , Pichot, Piendibene, Piergiovanni, Pierro, Gabriel , Pillant, Laurent , Pinard, Innocenzo, Pinto, Krzysztof , Piotrzkowski, Pirello, Pitkin, Wolfango , Plastino, Rosa , Poggiani, Yat-tung, Pong, Ponrathnam, Pasquale , Popolizio, Porter, Ed, Jade , Powell, Atul, Prajapati, Kiran , Prasai, Raghurama , Prasanna, Geraint , Pratten, Tanner , Prestegard, Principe, Prodi, Leonid , Prokhorov, Punturo, Puppo, Pürrer, Hong , Quetschke, Pedro, Quinonez, Fred, Raab, Geert , Raaijmakers, Hugh , Radkins, Radulesco, Raffai, Hanna , Rafferty, Sendhil , Raja, Rajan , Rajan, Binod , Rajbhandari, Malik , Rakhmanov, Karla, Ramirez, Antoni , Ramos-Buades, Javed , Rana, Kaushik , Rao, Piero , Rapagnani, Vivien , Raymond, Razzano, Jocelyn , Read, Tania , Regimbau, Rei, Reid, David, Reitze, Rettegno, Fulvio , Ricci, Colter, Richardson, Jonathan, Richardson, Paul, Ricker, Gunnar , Riemenschneider, Keith , Riles, Rizzo, Norna, Robertson, Florent , Robinet, Rocchi, Ramon, Rodriguez-Soto, Loic , Rolland, Jameson, Rollins, Vincent, Roma, Romanelli, Rocco , Romano, Chandra, Romel, Isobel, Romero-Shaw, Janeen, Romie, Caitlin, Rose, Dakota , Rose, Kyle , Dorota , Rosińska, Shawn, Rosofsky, Michael, Ross, Sheila , Rowan, Samuel, Rowlinson, Palash, Roy, Santosh , Roy, Paolo , Ruggi, Guntis , Rutins, Ryan, Surabhi , Sachdev, Travis , Sadecki, Mairi , Sakellariadou, Salafia, Om, Livio , Salconi, Muhammed , Saleem, Samajdar, Eduardo, Sanchez, Luis, Sanchez, Sanchis-Gual, Jaclyn, Sanders, Kevin, Santiago, Edison , Santos, Sarin, Sassolas, Sathyaprakash, B, Orion , Sauter, Richard, Savage, Vaibhav , Savant, Disha , Sawant, Sihem , Sayah, Dean , Schaetzl, Schale, Mark , Scheel, Scheuer, Patricia , Schmidt, Roman , Schnabel, Robert,  , Schofield, Axel , Schönbeck, Emil , Schreiber, Bernd, Schulte, Bernard, Schutz, Otto , Schwarm, Eyal , Schwartz, Jamie , Scott, Susan, Scott, Seidel, Sellers, Anand, Sengupta, Noah , Sennett, Sentenac, Valeria , Sequino, Sergeev, Yoshinta , Setyawati, Daniel, Shaddock, Shaffer, Selim, Shahriar, Sharma, Priyanka , Shawhan, Hongyu , Shen, Minori , Shikauchi, Rosalie , Shink, David, Shoemaker, Deirdre, Shoemaker, Keerti , Shukla, Shyamsundar , Shyamsundar, Karelle , Siellez, Magdalena , Sieniawska, Sigg, Leo, Singer, Divya , Singh, Neha , Ayatri , Singha, Akshat , Singhal, Alicia, Sintes, Sipala, Vasileios , Skliris, Bram,  , Slagmolen, Teresa, Slaven-Blair, Jiri , Smetana, Joshua, Smith, Rory,  , Smith, Surendranadh , Somala, Edwin, Son, Siddharth , Soni, Borja , Sorazu, Viola , Sordini, Fiodor , Sorrentino, Tarun , Souradeep, Sowell, Andrew, Spencer, Mario , Spera, Amit, Srivastava, Varun , Srivastava, Kai , Staats, Cosmin , Stachie, Standke, Daniele, Steer, Steinke, Steinlechner, Steinmeyer, Dane , Stocks, David, Stops, Madeline , Stover, Ken, Strain, Stratta, Amber , Strunk, Sturani, Amber, Stuver, Sudhagar , Sudhagar, Vivishek , Sudhir, Tiffany, Summerscales, Ling , Sun, Sunil , Sunil, Ankan , Sur, Jishnu , Suresh, Patrick, Sutton, Bas, Swinkels, Marek, Szczepańczyk, Tacca, Simon, Tait, Colm , Talbot, Andres, Tanasijczuk, David, Tanner, Duo , Tao, Marton , Tápai, Amauri , Tapia, Enzo, Tapia , San , Martin, Jay, Tasson, Taylor, Rodrigo , Tenorio, Lukas , Terkowski, Manasadevi, Thirugnanasambandam, Thomas, Jonathan, Thompson, Sivananda, Thondapu, Keith, Thorne, Thrane, Calley, Tinsman, Saravanan, Saravanan, Shubhanshu , Tiwari, Srishti , Karl , Toland, Mauro , Tonelli, Zeno , Tornasi, Alejandro , Torres-Forné, Calum, Torrie, Iara , Tosta , e , Melo, Töyrä, Emily, Trail, Travasso, Traylor, Maria, Tringali, Aashish , Tripathee, Agata , Trovato, Randy, Trudeau, Ka-wa, Tsang, Maggie , Tse, Rhondale , Tso, Leo , Tsukada, Daichi , Tsuna, Takuya , Tsutsui, Margherita , Turconi, Amit, Ubhi, Koh , Ueno, Dennis , Ugolini, Unnikrishnan, Cs, Alexander, Urban, Samantha, Usman, Andrei, Utina, Henning , Vahlbruch, Vajente, Guillermo , Valdes, Valentini, Vallisneri, Niels , van , Bakel, Martin , Beuzekom, den , Brand, Chris , Van , Den , Broeck, Daniel, Vander-Hyde, der , Schaaf, Joris, Van , Heijningen, Marielle, van , Veggel, Marco , Vardaro, Vijay , Varma, Steve , Vass, Matyas , Vasúth, Alberto , Vecchio, Gabriele , Vedovato, John , Veitch, Peter, Veitch, Krishna , Venkateswara, Gautam , Venugopalan, Didier , Verkindt, Doga , Veske, Vetrano, Viceré, Aaron, Viets, Serena , Vinciguerra, David, Vine, Jeanyves , Vinet, Salvatore , Vitale, Francisco , Hernandez , Vivanco, Thomas , Helios , Vocca, Cheryl , Vorvick, Sergey, Vyatchanin, Andrew, Wade, Leslie, Wade, Wade, Rob , Walet, Marissa , Walker, Gavin, Wallace, Larry , Wallace, Sinead , Walsh, Jonathan, Wang, Sibo , Wang, Wenhui, Wang, Yifan, Wang, Robert, Ward, Zane, Warden, Jim , Warner, Was, Jennifer , Watchi, Betsy , Weaver, Li-wei , Wei, Weinert, Alan, Weinstein, Rainer , Weiss, Felix , Wellmann, Linqing , Wen, Weßels, Jonathan, Westhouse, Wette, John, Whelan, Bernard, Whiting, Whittle, Dennis, Wilken, Williams, Roy, Williams, Andrew, Williamson, Joshua, Willis, Benno , Willke, Winkler, Christopher, Wipf, Holger , Wittel, Graham , Woan, Janis , Woehler, Jared, Wofford, Chun-fung , Wong, Jennifer, Wright, David, Wu, Daniel, Wysocki, Liting , Xiao, Hiro , Yamamoto, Le , Yang, Yang , Ziyan , Min-jet, Yap, Maher , Yazback, David, Yeeles, Hang , Haocun , Shingheirobin , Yuen, Adam, Zadrożny, Zadrożny, Zanolin, Tatiana , Zelenova, Jean-pierre , Zendri, Zevin, Jue , Zhang, Liyuan , Teng , Chunnong , Zhao, Guoying , Minchuan , Zhou, Zifan , Xingjiang, Zhu, Aaron, Zimmerman, Michael, Zucker, John , Zweizig, Laboratoire des matériaux avancés (LMA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux (ARTEMIS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut des Fonctions Optiques pour les Technologies de l'informatiON (Institut FOTON), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Kastler Brossel (LKB [Collège de France]), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF (institution))-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut Lumière Matière [Villeurbanne] (ILM), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut des Hautes Études Scientifiques (IHES), IHES, LIGO Scientific, Virgo, (Astro)-Particles Physics, LIGO Scientific Collaboration, Virgo Collaboration, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Collège de France (CdF (institution)), Spectroscopies optiques des matériaux verres, amorphes et à nanoparticules (SOPRANO), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut des Hautes Etudes Scientifiques (IHES), Agencia Estatal de Investigación (España), Generalitat de Catalunya, Generalitat Valenciana, European Commission, Grav. waves and fundamental physics, RS: FSE Grav. waves and fundamental physics, RS: FSE MSP, Abbott, R., Abbott, T. D., Abraham, S., Acernese, F., Ackley, K., Adams, C., Adhikari, R. X., Adya, V. B., Affeldt, C., Agathos, M., Agatsuma, K., Aggarwal, N., Aguiar, O. D., Aich, A., Aiello, L., Ain, A., Ajith, P., Allen, G., Allocca, A., Altin, P. A., Amato, A., Anand, S., Ananyeva, A., Anderson, S. B., Anderson, W. G., Angelova, S. V., Ansoldi, S., Antier, S., Appert, S., Arai, K., Araya, M. C., Areeda, J. S., Arène, M., Arnaud, N., Aronson, S. M., Arun, K. G., Ascenzi, S., Ashton, G., Aston, S. M., Astone, P., Aubin, F., Aufmuth, P., Aultoneal, K., Austin, C., Avendano, V., Babak, S., Bacon, P., Badaracco, F., Bader, M. K. M., Bae, S., Baer, A. M., Baird, J., Baldaccini, F., Ballardin, G., Ballmer, S. W., Bals, A., Balsamo, A., Baltus, G., Banagiri, S., Bankar, D., Bankar, R. S., Barayoga, J. C., Barbieri, C., Barish, B. C., Barker, D., Barkett, K., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Bartos, I., Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Bazzan, M., Bécsy, B., Bejger, M., Belahcene, I., Bell, A. S., Beniwal, D., Benjamin, M. G., Bentley, J. D., Bergamin, F., Berger, B. K., Bergmann, G., Bernuzzi, S., Berry, C. P. L., Bersanetti, D., Bertolini, A., Betzwieser, J., Bhandare, R., Bhandari, A. V., Bidler, J., Biggs, E., Bilenko, I. A., Billingsley, G., Birney, R., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Bissenbayeva, G., Bitossi, M., Bizouard, M. A., Blackburn, J. K., Blackman, J., Blair, C. D., Blair, D. G., Blair, R. M., Bobba, F., Bode, N., Boer, M., Boetzel, Y., Bogaert, G., Bondu, F., Bonilla, E., Bonnand, R., Booker, P., Boom, B. A., Bork, R., Boschi, V., Bose, S., Bossilkov, V., Bosveld, J., Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. R., Bramley, A., Branchesi, M., Brau, J. E., Breschi, M., Briant, T., Briggs, J. H., Brighenti, F., Brillet, A., Brinkmann, M., Brockill, P., Brooks, A. F., Brooks, J., Brown, D. D., Brunett, S., Bruno, G., Bruntz, R., Buikema, A., Bulik, T., Bulten, H. J., Buonanno, A., Buskulic, D., Byer, R. L., Cabero, M., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. Calderón, Callaghan, J. D., Callister, T. A., Calloni, E., Camp, J. B., Canepa, M., Cannon, K. C., Cao, H., Cao, J., Carapella, G., Carbognani, F., Caride, S., Carney, M. F., Carullo, G., Diaz, J. Casanueva, Casentini, C., Castañeda, J., Caudill, S., Cavaglià, M., Cavalier, F., Cavalieri, R., Cella, G., Cerdá-Durán, P., Cesarini, E., Chaibi, O., Chakravarti, K., Chan, C., Chan, M., Chao, S., Charlton, P., Chase, E. A., Chassande-Mottin, E., Chatterjee, D., Chaturvedi, M., Chen, H. Y., Chen, X., Chen, Y., Cheng, H. -P., Cheong, C. K., Chia, H. Y., Chiadini, F., Chierici, R., Chincarini, A., Chiummo, A., Cho, G., Cho, H. S., Cho, M., Christensen, N., Chu, Q., Chua, S., Chung, K. W., Chung, S., Ciani, G., Ciecielag, P., Cieślar, M., Ciobanu, A. A., Ciolfi, R., Cipriano, F., Cirone, A., Clara, F., Clark, J. A., Clearwater, P., Clesse, S., Cleva, F., Coccia, E., Cohadon, P. -F., Cohen, D., Colleoni, M., Collette, C. G., Collins, C., Colpi, M., Constancio, M., Conti, L., Cooper, S. J., Corban, P., Corbitt, T. R., Cordero-Carrión, I., Corezzi, S., Corley, K. R., Cornish, N., Corre, D., Corsi, A., Cortese, S., Costa, C. A., Cotesta, R., Coughlin, M. W., Coughlin, S. B., Coulon, J. -P., Countryman, S. T., Couvares, P., Covas, P. B., Coward, D. M., Cowart, M. J., Coyne, D. C., Coyne, R., Creighton, J. D. E., Creighton, T. D., Cripe, J., Croquette, M., Crowder, S. G., Cudell, J. -R., Cullen, T. J., Cumming, A., Cummings, R., Cunningham, L., Cuoco, E., Curylo, M., Canton, T. Dal, Dálya, G., Dana, A., Daneshgaran-Bajastani, L. M., D’Angelo, B., Danilishin, S. L., D’Antonio, S., Danzmann, K., Darsow-Fromm, C., Dasgupta, A., Datrier, L. E. H., Dattilo, V., Dave, I., Davier, M., Davies, G. S., Davis, D., Daw, E. J., Debra, D., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deléglise, S., Delfavero, M., De Lillo, N., Del Pozzo, W., Demarchi, L. M., D’Emilio, V., Demos, N., Dent, T., De Pietri, R., De Rosa, R., De Rossi, C., Desalvo, R., de Varona, O., Dhurandhar, S., Díaz, M. C., Diaz-Ortiz, M., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giorgio, C., Di Giovanni, F., Di Giovanni, M., Di Girolamo, T., Di Lieto, A., Ding, B., Di Pace, S., Di Palma, I., Di Renzo, F., Divakarla, A. K., Dmitriev, A., Doctor, Z., Donovan, F., Dooley, K. L., Doravari, S., Dorrington, I., Downes, T. P., Drago, M., Driggers, J. C., Du, Z., Ducoin, J. -G., Dupej, P., Durante, O., D’Urso, D., Dwyer, S. E., Easter, P. J., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Ehrens, P., Eichholz, J., Eikenberry, S. S., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Errico, L., Essick, R. C., Estelles, H., Estevez, D., Etienne, Z. B., Etzel, T., Evans, M., Evans, T. M., Ewing, B. E., Fafone, V., Fairhurst, S., Fan, X., Farinon, S., Farr, B., Farr, W. M., Fauchon-Jones, E. J., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Feng, F., Fenyvesi, E., Ferguson, D. L., Fernandez-Galiana, A., Ferrante, I., Ferreira, E. C., Ferreira, T. A., Fidecaro, F., Fiori, I., Fiorucci, D., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fitz-Axen, M., Fiumara, V., Flaminio, R., Floden, E., Flynn, E., Fong, H., Font, J. A., Forsyth, P. W. F., Fournier, J. -D., Frasca, S., Frasconi, F., Frei, Z., Freise, A., Frey, R., Frey, V., Fritschel, P., Frolov, V. V., Fronzè, G., Fulda, P., Fyffe, M., Gabbard, H. A., Gadre, B. U., Gaebel, S. M., Gair, J. R., Galaudage, S., Ganapathy, D., Gaonkar, S. G., García-Quirós, C., Garufi, F., Gateley, B., Gaudio, S., Gayathri, V., Gemme, G., Genin, E., Gennai, A., George, D., George, J., Gergely, L., Ghonge, S., Ghosh, Abhirup, Ghosh, Archisman, Ghosh, S., Giacomazzo, B., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gier, C., Gill, K., Glanzer, J., Gniesmer, J., Godwin, P., Goetz, E., Goetz, R., Gohlke, N., Goncharov, B., González, G., Gopakumar, A., Gossan, S. E., Gosselin, M., Gouaty, R., Grace, B., Grado, A., Granata, M., Grant, A., Gras, S., Grassia, P., Gray, C., Gray, R., Greco, G., Green, A. C., Green, R., Gretarsson, E. M., Griggs, H. L., Grignani, G., Grimaldi, A., Grimm, S. J., Grote, H., Grunewald, S., Gruning, P., Guidi, G. M., Guimaraes, A. R., Guixé, G., Gulati, H. K., Guo, Y., Gupta, A., Gupta, Anchal, Gupta, P., Gustafson, E. K., Gustafson, R., Haegel, L., Halim, O., Hall, E. D., Hamilton, E. Z., Hammond, G., Haney, M., Hanke, M. M., Hanks, J., Hanna, C., Hannam, M. D., Hannuksela, O. A., Hansen, T. J., Hanson, J., Harder, T., Hardwick, T., Haris, K., Harms, J., Harry, G. M., Harry, I. W., Hasskew, R. K., Haster, C. -J., Haughian, K., Hayes, F. J., Healy, J., Heidmann, A., Heintze, M. C., Heinze, J., Heitmann, H., Hellman, F., Hello, P., Hemming, G., Hendry, M., Heng, I. S., Hennes, E., Hennig, J., Heurs, M., Hild, S., Hinderer, T., Hoback, S. Y., Hochheim, S., Hofgard, E., Hofman, D., Holgado, A. M., Holland, N. A., Holt, K., Holz, D. E., Hopkins, P., Horst, C., Hough, J., Howell, E. J., Hoy, C. G., Huang, Y., Hübner, M. T., Huerta, E. A., Huet, D., Hughey, B., Hui, V., Husa, S., Huttner, S. H., Huxford, R., Huynh-Dinh, T., Idzkowski, B., Iess, A., Inchauspe, H., Ingram, C., Intini, G., Isac, J. - M., Isi, M., Iyer, B. R., Jacqmin, T., Jadhav, S. J., Jadhav, S. P., James, A. L., Jani, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jaume, R., Jenkins, A. C., Jiang, J., Johns, G. R., Jones, A. W., Jones, D. I., Jones, J. D., Jones, P., Jones, R., Jonker, R. J. G., Ju, L., Junker, J., Kalaghatgi, C. V., Kalogera, V., Kamai, B., Kandhasamy, S., Kang, G., Kanner, J. B., Kapadia, S. J., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Katsanevas, S., Katsavounidis, E., Katzman, W., Kaufer, S., Kawabe, K., Kéfélian, F., Keitel, D., Keivani, A., Kennedy, R., Key, J. S., Khadka, S., Khalili, F. Y., Khan, I., Khan, S., Khan, Z. A., Khazanov, E. A., Khetan, N., Khursheed, M., Kijbunchoo, N., Kim, Chunglee, Kim, G. J., Kim, J. C., Kim, K., Kim, W., Kim, W. S., Kim, Y. -M., Kimball, C., King, P. J., Kinley-Hanlon, M., Kirchhoff, R., Kissel, J. S., Kleybolte, L., Klimenko, S., Knowles, T. D., Koch, P., Koehlenbeck, S. M., Koekoek, G., Koley, S., Kondrashov, V., Kontos, A., Koper, N., Korobko, M., Korth, W. Z., Kovalam, M., Kozak, D. B., Kringel, V., Krishnendu, N. V., Królak, A., Krupinski, N., Kuehn, G., Kumar, A., Kumar, P., Kumar, Rahul, Kumar, Rakesh, Kumar, S., Kuo, L., Kutynia, A., Lackey, B. D., Laghi, D., Lalande, E., Lam, T. L., Lamberts, A., Landry, M., Lane, B. B., Lang, R. N., Lange, J., Lantz, B., Lanza, R. K., La Rosa, I., Lartaux-Vollard, A., Lasky, P. D., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., Leavey, S., Lecoeuche, Y. K., Lee, C. H., Lee, H. M., Lee, H. W., Lee, J., Lee, K., Lehmann, J., Leroy, N., Letendre, N., Levin, Y., Li, A. K. Y., Li, J., Li, K., Li, T. G. F., Li, X., Linde, F., Linker, S. D., Linley, J. N., Littenberg, T. B., Liu, J., Liu, X., Llorens-Monteagudo, M., Lo, R. K. L., Lockwood, A., London, L. T., Longo, A., Lorenzini, M., Loriette, V., Lormand, M., Losurdo, G., Lough, J. D., Lousto, C. O., Lovelace, G., Lück, H., Lumaca, D., Lundgren, A. P., Ma, Y., Macas, R., Macfoy, S., Macinnis, M., Macleod, D. M., Macmillan, I. A. O., Macquet, A., Hernandez, I. Magaña, Magaña-Sandoval, F., Magee, R. M., Majorana, E., Maksimovic, I., Malik, A., Man, N., Mandic, V., Mangano, V., Mansell, G. L., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Marion, F., Márka, S., Márka, Z., Markakis, C., Markosyan, A. S., Markowitz, A., Maros, E., Marquina, A., Marsat, S., Martelli, F., Martin, I. W., Martin, R. M., Martinez, V., Martynov, D. V., Masalehdan, H., Mason, K., Massera, E., Masserot, A., Massinger, T. J., Masso-Reid, M., Mastrogiovanni, S., Matas, A., Matichard, F., Mavalvala, N., Maynard, E., Mccann, J. J., Mccarthy, R., Mcclelland, D. E., Mccormick, S., Mcculler, L., Mcguire, S. C., Mcisaac, C., Mciver, J., Mcmanus, D. J., Mcrae, T., Mcwilliams, S. T., Meacher, D., Meadors, G. D., Mehmet, M., Mehta, A. K., Villa, E. Mejuto, Melatos, A., Mendell, G., Mercer, R. A., Mereni, L., Merfeld, K., Merilh, E. L., Merritt, J. D., Merzougui, M., Meshkov, S., Messenger, C., Messick, C., Metzdorff, R., Meyers, P. M., Meylahn, F., Mhaske, A., Miani, A., Miao, H., Michaloliakos, I., Michel, C., Middleton, H., Milano, L., Miller, A. L., Millhouse, M., Mills, J. C., Milotti, E., Milovich-Goff, M. C., Minazzoli, O., Minenkov, Y., Mishkin, A., Mishra, C., Mistry, T., Mitra, S., Mitrofanov, V. P., Mitselmakher, G., Mittleman, R., Mo, G., Mogushi, K., Mohapatra, S. R. P., Mohite, S. R., Molina-Ruiz, M., Mondin, M., Montani, M., Moore, C. J., Moraru, D., Morawski, F., Moreno, G., Morisaki, S., Mours, B., Mow-Lowry, C. M., Mozzon, S., Muciaccia, F., Mukherjee, Arunava, Mukherjee, D., Mukherjee, S., Mukherjee, Subroto, Mukund, N., Mullavey, A., Munch, J., Muñiz, E. A., Murray, P. G., Nagar, A., Nardecchia, I., Naticchioni, L., Nayak, R. K., Neil, B. F., Neilson, J., Nelemans, G., Nelson, T. J. N., Nery, M., Neunzert, A., Ng, K. Y., Ng, S., Nguyen, C., Nguyen, P., Nichols, D., Nichols, S. A., Nissanke, S., Nocera, F., Noh, M., North, C., Nothard, D., Nuttall, L. K., Oberling, J., O’Brien, B. D., Oganesyan, G., Ogin, G. H., Oh, J. J., Oh, S. H., Ohme, F., Ohta, H., Okada, M. A., Oliver, M., Olivetto, C., Oppermann, P., Oram, Richard J., O’Reilly, B., Ormiston, R. G., Ortega, L. F., O’Shaughnessy, R., Ossokine, S., Osthelder, C., Ottaway, D. J., Overmier, H., Owen, B. J., Pace, A. E., Pagano, G., Page, M. A., Pagliaroli, G., Pai, A., Pai, S. A., Palamos, J. R., Palashov, O., Palomba, C., Pan, H., Panda, P. K., Pang, P. T. H., Pankow, C., Pannarale, F., Pant, B. C., Paoletti, F., Paoli, A., Parida, A., Parker, W., Pascucci, D., Pasqualetti, A., Passaquieti, R., Passuello, D., Patricelli, B., Payne, E., Pearlstone, B. L., Pechsiri, T. C., Pedersen, A. J., Pedraza, M., Pele, A., Penn, S., Perego, A., Perez, C. J., Périgois, C., Perreca, A., Perriès, S., Petermann, J., Pfeiffer, H. P., Phelps, M., Phukon, K. S., Piccinni, O. J., Pichot, M., Piendibene, M., Piergiovanni, F., Pierro, V., Pillant, G., Pinard, L., Pinto, I. M., Piotrzkowski, K., Pirello, M., Pitkin, M., Plastino, W., Poggiani, R., Pong, D. Y. T., Ponrathnam, S., Popolizio, P., Porter, E. K., Powell, J., Prajapati, A. K., Prasai, K., Prasanna, R., Pratten, G., Prestegard, T., Principe, M., Prodi, G. A., Prokhorov, L., Punturo, M., Puppo, P., Pürrer, M., Qi, H., Quetschke, V., Quinonez, P. J., Raab, F. J., Raaijmakers, G., Radkins, H., Radulesco, N., Raffai, P., Rafferty, H., Raja, S., Rajan, C., Rajbhandari, B., Rakhmanov, M., Ramirez, K. E., Ramos-Buades, A., Rana, Javed, Rao, K., Rapagnani, P., Raymond, V., Razzano, M., Read, J., Regimbau, T., Rei, L., Reid, S., Reitze, D. H., Rettegno, P., Ricci, F., Richardson, C. J., Richardson, J. W., Ricker, P. M., Riemenschneider, G., Riles, K., Rizzo, M., Robertson, N. A., Robinet, F., Rocchi, A., Rodriguez-Soto, R. D., Rolland, L., Rollins, J. G., Roma, V. J., Romanelli, M., Romano, R., Romel, C. L., Romero-Shaw, I. M., Romie, J. H., Rose, C. A., Rose, D., Rose, K., Rosińska, D., Rosofsky, S. G., Ross, M. P., Rowan, S., Rowlinson, S. J., Roy, P. K., Roy, Santosh, Roy, Soumen, Ruggi, P., Rutins, G., Ryan, K., Sachdev, S., Sadecki, T., Sakellariadou, M., Salafia, O. S., Salconi, L., Saleem, M., Samajdar, A., Sanchez, E. J., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Santiago, K. A., Santos, E., Sarin, N., Sassolas, B., Sathyaprakash, B. S., Sauter, O., Savage, R. L., Savant, V., Sawant, D., Sayah, S., Schaetzl, D., Schale, P., Scheel, M., Scheuer, J., Schmidt, P., Schnabel, R., Schofield, R. M. S., Schönbeck, A., Schreiber, E., Schulte, B. W., Schutz, B. F., Schwarm, O., Schwartz, E., Scott, J., Scott, S. M., Seidel, E., Sellers, D., Sengupta, A. S., Sennett, N., Sentenac, D., Sequino, V., Sergeev, A., Setyawati, Y., Shaddock, D. A., Shaffer, T., Shahriar, M. S., Sharma, A., Sharma, P., Shawhan, P., Shen, H., Shikauchi, M., Shink, R., Shoemaker, D. H., Shoemaker, D. M., Shukla, K., Shyamsundar, S., Siellez, K., Sieniawska, M., Sigg, D., Singer, L. P., Singh, D., Singh, N., Singha, A., Singhal, A., Sintes, A. M., Sipala, V., Skliris, V., Slagmolen, B. J. J., Slaven-Blair, T. J., Smetana, J., Smith, J. R., Smith, R. J. E., Somala, S., Son, E. J., Soni, S., Sorazu, B., Sordini, V., Sorrentino, F., Souradeep, T., Sowell, E., Spencer, A. P., Spera, M., Srivastava, A. K., Srivastava, V., Staats, K., Stachie, C., Standke, M., Steer, D. A., Steinke, M., Steinlechner, J., Steinlechner, S., Steinmeyer, D., Stocks, D., Stops, D. J., Stover, M., Strain, K. A., Stratta, G., Strunk, A., Sturani, R., Stuver, A. L., Sudhagar, S., Sudhir, V., Summerscales, T. Z., Sun, L., Sunil, S., Sur, A., Suresh, J., Sutton, P. J., Swinkels, B. L., Szczepańczyk, M. J., Tacca, M., Tait, S. C., Talbot, C., Tanasijczuk, A. J., Tanner, D. B., Tao, D., Tápai, M., Tapia, A., Martin, E. N. Tapia San, Tasson, J. D., Taylor, R., Tenorio, R., Terkowski, L., Thirugnanasambandam, M. P., Thomas, M., Thomas, P., Thompson, J. E., Thondapu, S. R., Thorne, K. A., Thrane, E., Tinsman, C. L., Saravanan, T. R., Tiwari, Shubhanshu, Tiwari, S., Tiwari, V., Toland, K., Tonelli, M., Tornasi, Z., Torres-Forné, A., Torrie, C. I., Tosta e Melo, I., Töyrä, D., Trail, E. A., Travasso, F., Traylor, G., Tringali, M. C., Tripathee, A., Trovato, A., Trudeau, R. J., Tsang, K. W., Tse, M., Tso, R., Tsukada, L., Tsuna, D., Tsutsui, T., Turconi, M., Ubhi, A. S., Ueno, K., Ugolini, D., Unnikrishnan, C. S., Urban, A. L., Usman, S. A., Utina, A. C., Vahlbruch, H., Vajente, G., Valdes, G., Valentini, M., Vallisneri, M., van Bakel, N., van Beuzekom, M., van den Brand, J. F. J., Van Den Broeck, C., Vander-Hyde, D. C., van der Schaaf, L., Van Heijningen, J. V., van Veggel, A. A., Vardaro, M., Varma, V., Vass, S., Vasúth, M., Vecchio, A., Vedovato, G., Veitch, J., Veitch, P. J., Venkateswara, K., Venugopalan, G., Verkindt, D., Veske, D., Vetrano, F., Viceré, A., Viets, A. D., Vinciguerra, S., Vine, D. J., Vinet, J. -Y., Vitale, S., Vivanco, Francisco Hernandez, Vo, T., Vocca, H., Vorvick, C., Vyatchanin, S. P., Wade, A. R., Wade, L. E., Wade, M., Walet, R., Walker, M., Wallace, G. S., Wallace, L., Walsh, S., Wang, J. Z., Wang, S., Wang, W. H., Wang, Y. F., Ward, R. L., Warden, Z. A., Warner, J., Was, M., Watchi, J., Weaver, B., Wei, L. -W., Weinert, M., Weinstein, A. J., Weiss, R., Wellmann, F., Wen, L., Weßels, P., Westhouse, J. W., Wette, K., Whelan, J. T., Whiting, B. F., Whittle, C., Wilken, D. M., Williams, D., Williams, R. D., Williamson, A. R., Willis, J. L., Willke, B., Winkler, W., Wipf, C. C., Wittel, H., Woan, G., Woehler, J., Wofford, J. K., Wong, C., Wright, J. L., Wu, D. S., Wysocki, D. M., Xiao, L., Yamamoto, H., Yang, L., Yang, Y., Yang, Z., Yap, M. J., Yazback, M., Yeeles, D. W., Yu, Hang, Yu, Haocun, Yuen, S. H. R., Zadrożny, A. K., Zadrożny, A., Zanolin, M., Zelenova, T., Zendri, J. -P., Zevin, M., Zhang, J., Zhang, L., Zhang, T., Zhao, C., Zhao, G., Zhou, M., Zhou, Z., Zhu, X. J., Zimmerman, A. B., Zucker, M. E., Zweizig, J., Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Université Nice Sophia Antipolis (... - 2019) (UNS), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Collège de France (CdF (institution)), Abbott, R, Abbott, T, Abraham, S, Acernese, F, Ackley, K, Adams, C, Adhikari, R, Adya, V, Affeldt, C, Agathos, M, Agatsuma, K, Aggarwal, N, Aguiar, O, Aich, A, Aiello, L, Ain, A, Ajith, P, Allen, G, Allocca, A, Altin, P, Amato, A, Anand, S, Ananyeva, A, Anderson, S, Anderson, W, Angelova, S, Ansoldi, S, Antier, S, Appert, S, Arai, K, Araya, M, Areeda, J, Arene, M, Arnaud, N, Aronson, S, Arun, K, Ascenzi, S, Ashton, G, Aston, S, Astone, P, Aubin, F, Aufmuth, P, Aultoneal, K, Austin, C, Avendano, V, Babak, S, Bacon, P, Badaracco, F, Bader, M, Bae, S, Baer, A, Baird, J, Baldaccini, F, Ballardin, G, Ballmer, S, Bals, A, Balsamo, A, Baltus, G, Banagiri, S, Bankar, D, Bankar, R, Barayoga, J, Barbieri, C, Barish, B, Barker, D, Barkett, K, Barneo, P, Barone, F, Barr, B, Barsotti, L, Barsuglia, M, Barta, D, Bartlett, J, Bartos, I, Bassiri, R, Basti, A, Bawaj, M, Bayley, J, Bazzan, M, Becsy, B, Bejger, M, Belahcene, I, Bell, A, Beniwal, D, Benjamin, M, Bentley, J, Bergamin, F, Berger, B, Bergmann, G, Bernuzzi, S, Berry, C, Bersanetti, D, Bertolini, A, Betzwieser, J, Bhandare, R, Bhandari, A, Bidler, J, Biggs, E, Bilenko, I, Billingsley, G, Birney, R, Birnholtz, O, Biscans, S, Bischi, M, Biscoveanu, S, Bisht, A, Bissenbayeva, G, Bitossi, M, Bizouard, M, Blackburn, J, Blackman, J, Blair, C, Blair, D, Blair, R, Bobba, F, Bode, N, Boer, M, Boetzel, Y, Bogaert, G, Bondu, F, Bonilla, E, Bonnand, R, Booker, P, Boom, B, Bork, R, Boschi, V, Bose, S, Bossilkov, V, Bosveld, J, Bouffanais, Y, Bozzi, A, Bradaschia, C, Brady, P, Bramley, A, Branchesi, M, Brau, J, Breschi, M, Briant, T, Briggs, J, Brighenti, F, Brillet, A, Brinkmann, M, Brockill, P, Brooks, A, Brooks, J, Brown, D, Brunett, S, Bruno, G, Bruntz, R, Buikema, A, Bulik, T, Bulten, H, Buonanno, A, Buskulic, D, Byer, R, Cabero, M, Cadonati, L, Cagnoli, G, Cahillane, C, Bustillo, J, Callaghan, J, Callister, T, Calloni, E, Camp, J, Canepa, M, Cannon, K, Cao, H, Cao, J, Carapella, G, Carbognani, F, Caride, S, Carney, M, Carullo, G, Diaz, J, Casentini, C, Castaneda, J, Caudill, S, Cavaglia, M, Cavalier, F, Cavalieri, R, Cella, G, Cerda-Duran, P, Cesarini, E, Chaibi, O, Chakravarti, K, Chan, C, Chan, M, Chao, S, Charlton, P, Chase, E, Chassande-Mottin, E, Chatterjee, D, Chaturvedi, M, Chen, H, Chen, X, Chen, Y, Cheng, H, Cheong, C, Chia, H, Chiadini, F, Chierici, R, Chincarini, A, Chiummo, A, Cho, G, Cho, H, Cho, M, Christensen, N, Chu, Q, Chua, S, Chung, K, Chung, S, Ciani, G, Ciecielag, P, Cieslar, M, Ciobanu, A, Ciolfi, R, Cipriano, F, Cirone, A, Clara, F, Clark, J, Clearwater, P, Clesse, S, Cleva, F, Coccia, E, Cohadon, P, Cohen, D, Colleoni, M, Collette, C, Collins, C, Colpi, M, Constancio, M, Conti, L, Cooper, S, Corban, P, Corbitt, T, Cordero-Carrion, I, Corezzi, S, Corley, K, Cornish, N, Corre, D, Corsi, A, Cortese, S, Costa, C, Cotesta, R, Coughlin, M, Coughlin, S, Coulon, J, Countryman, S, Couvares, P, Covas, P, Coward, D, Cowart, M, Coyne, D, Coyne, R, Creighton, J, Creighton, T, Cripe, J, Croquette, M, Crowder, S, Cudell, J, Cullen, T, Cumming, A, Cummings, R, Cunningham, L, Cuoco, E, Curylo, M, Canton, T, Dalya, G, Dana, A, Daneshgaran-Bajastani, L, D'Angelo, B, Danilishin, S, D'Antonio, S, Danzmann, K, Darsow-Fromm, C, Dasgupta, A, Datrier, L, Dattilo, V, Dave, I, Davier, M, Davies, G, Davis, D, Daw, E, Debra, D, Deenadayalan, M, Degallaix, J, De Laurentis, M, Deleglise, S, Delfavero, M, De Lillo, N, Del Pozzo, W, Demarchi, L, D'Emilio, V, Demos, N, Dent, T, De Pietri, R, De Rosa, R, De Rossi, C, Desalvo, R, de Varona, O, Dhurandhar, S, Diaz, M, Diaz-Ortiz, M, Dietrich, T, Di Fiore, L, Di Fronzo, C, Di Giorgio, C, Di Giovanni, F, Di Giovanni, M, Di Girolamo, T, Di Lieto, A, Ding, B, Di Pace, S, Di Palma, I, Di Renzo, F, Divakarla, A, Dmitriev, A, Doctor, Z, Donovan, F, Dooley, K, Doravari, S, Dorrington, I, Downes, T, Drago, M, Driggers, J, Du, Z, Ducoin, J, Dupej, P, Durante, O, D'Urso, D, Dwyer, S, Easter, P, Eddolls, G, Edelman, B, Edo, T, Edy, O, Effler, A, Ehrens, P, Eichholz, J, Eikenberry, S, Eisenmann, M, Eisenstein, R, Ejlli, A, Errico, L, Essick, R, Estelles, H, Estevez, D, Etienne, Z, Etzel, T, Evans, M, Evans, T, Ewing, B, Fafone, V, Fairhurst, S, Fan, X, Farinon, S, Farr, B, Farr, W, Fauchon-Jones, E, Favata, M, Fays, M, Fazio, M, Feicht, J, Fejer, M, Feng, F, Fenyvesi, E, Ferguson, D, Fernandez-Galiana, A, Ferrante, I, Ferreira, E, Ferreira, T, Fidecaro, F, Fiori, I, Fiorucci, D, Fishbach, M, Fisher, R, Fittipaldi, R, Fitz-Axen, M, Fiumara, V, Flaminio, R, Floden, E, Flynn, E, Fong, H, Font, J, Forsyth, P, Fournier, J, Frasca, S, Frasconi, F, Frei, Z, Freise, A, Frey, R, Frey, V, Fritschel, P, Frolov, V, Fronze, G, Fulda, P, Fyffe, M, Gabbard, H, Gadre, B, Gaebel, S, Gair, J, Galaudage, S, Ganapathy, D, Gaonkar, S, Garcia-Quiros, C, Garufi, F, Gateley, B, Gaudio, S, Gayathri, V, Gemme, G, Genin, E, Gennai, A, George, D, George, J, Gergely, L, Ghonge, S, Ghosh, A, Ghosh, S, Giacomazzo, B, Giaime, J, Giardina, K, Gibson, D, Gier, C, Gill, K, Glanzer, J, Gniesmer, J, Godwin, P, Goetz, E, Goetz, R, Gohlke, N, Goncharov, B, Gonzalez, G, Gopakumar, A, Gossan, S, Gosselin, M, Gouaty, R, Grace, B, Grado, A, Granata, M, Grant, A, Gras, S, Grassia, P, Gray, C, Gray, R, Greco, G, Green, A, Green, R, Gretarsson, E, Griggs, H, Grignani, G, Grimaldi, A, Grimm, S, Grote, H, Grunewald, S, Gruning, P, Guidi, G, Guimaraes, A, Guixe, G, Gulati, H, Guo, Y, Gupta, A, Gupta, P, Gustafson, E, Gustafson, R, Haegel, L, Halim, O, Hall, E, Hamilton, E, Hammond, G, Haney, M, Hanke, M, Hanks, J, Hanna, C, Hannam, M, Hannuksela, O, Hansen, T, Hanson, J, Harder, T, Hardwick, T, Haris, K, Harms, J, Harry, G, Harry, I, Hasskew, R, Haster, C, Haughian, K, Hayes, F, Healy, J, Heidmann, A, Heintze, M, Heinze, J, Heitmann, H, Hellman, F, Hello, P, Hemming, G, Hendry, M, Heng, I, Hennes, E, Hennig, J, Heurs, M, Hild, S, Hinderer, T, Hoback, S, Hochheim, S, Hofgard, E, Hofman, D, Holgado, A, Holland, N, Holt, K, Holz, D, Hopkins, P, Horst, C, Hough, J, Howell, E, Hoy, C, Huang, Y, Hubner, M, Huerta, E, Huet, D, Hughey, B, Hui, V, Husa, S, Huttner, S, Huxford, R, Huynh-Dinh, T, Idzkowski, B, Iess, A, Inchauspe, H, Ingram, C, Intini, G, Isac, J, Isi, M, Iyer, B, Jacqmin, T, Jadhav, S, James, A, Jani, K, Janthalur, N, Jaranowski, P, Jariwala, D, Jaume, R, Jenkins, A, Jiang, J, Johns, G, Jones, A, Jones, D, Jones, J, Jones, P, Jones, R, Jonker, R, Ju, L, Junker, J, Kalaghatgi, C, Kalogera, V, Kamai, B, Kandhasamy, S, Kang, G, Kanner, J, Kapadia, S, Karki, S, Kashyap, R, Kasprzack, M, Kastaun, W, Katsanevas, S, Katsavounidis, E, Katzman, W, Kaufer, S, Kawabe, K, Kefelian, F, Keitel, D, Keivani, A, Kennedy, R, Key, J, Khadka, S, Khalili, F, Khan, I, Khan, S, Khan, Z, Khazanov, E, Khetan, N, Khursheed, M, Kijbunchoo, N, Kim, C, Kim, G, Kim, J, Kim, K, Kim, W, Kim, Y, Kimball, C, King, P, Kinley-Hanlon, M, Kirchhoff, R, Kissel, J, Kleybolte, L, Klimenko, S, Knowles, T, Koch, P, Koehlenbeck, S, Koekoek, G, Koley, S, Kondrashov, V, Kontos, A, Koper, N, Korobko, M, Korth, W, Kovalam, M, Kozak, D, Kringel, V, Krishnendu, N, Krolak, A, Krupinski, N, Kuehn, G, Kumar, A, Kumar, P, Kumar, R, Kumar, S, Kuo, L, Kutynia, A, Lackey, B, Laghi, D, Lalande, E, Lam, T, Lamberts, A, Landry, M, Lane, B, Lang, R, Lange, J, Lantz, B, Lanza, R, La Rosa, I, Lartaux-Vollard, A, Lasky, P, Laxen, M, Lazzarini, A, Lazzaro, C, Leaci, P, Leavey, S, Lecoeuche, Y, Lee, C, Lee, H, Lee, J, Lee, K, Lehmann, J, Leroy, N, Letendre, N, Levin, Y, Li, A, Li, J, Li, K, Li, T, Li, X, Linde, F, Linker, S, Linley, J, Littenberg, T, Liu, J, Liu, X, Llorens-Monteagudo, M, Lo, R, Lockwood, A, London, L, Longo, A, Lorenzini, M, Loriette, V, Lormand, M, Losurdo, G, Lough, J, Lousto, C, Lovelace, G, Luck, H, Lumaca, D, Lundgren, A, Ma, Y, Macas, R, Macfoy, S, Macinnis, M, Macleod, D, Macmillan, I, Macquet, A, Hernandez, I, Magana-Sandoval, F, Magee, R, Majorana, E, Maksimovic, I, Malik, A, Man, N, Mandic, V, Mangano, V, Mansell, G, Manske, M, Mantovani, M, Mapelli, M, Marchesoni, F, Marion, F, Marka, S, Marka, Z, Markakis, C, Markosyan, A, Markowitz, A, Maros, E, Marquina, A, Marsat, S, Martelli, F, Martin, I, Martin, R, Martinez, V, Martynov, D, Masalehdan, H, Mason, K, Massera, E, Masserot, A, Massinger, T, Masso-Reid, M, Mastrogiovanni, S, Matas, A, Matichard, F, Mavalvala, N, Maynard, E, Mccann, J, Mccarthy, R, Mcclelland, D, Mccormick, S, Mcculler, L, Mcguire, S, Mcisaac, C, Mciver, J, Mcmanus, D, Mcrae, T, Mcwilliams, S, Meacher, D, Meadors, G, Mehmet, M, Mehta, A, Villa, E, Melatos, A, Mendell, G, Mercer, R, Mereni, L, Merfeld, K, Merilh, E, Merritt, J, Merzougui, M, Meshkov, S, Messenger, C, Messick, C, Metzdorff, R, Meyers, P, Meylahn, F, Mhaske, A, Miani, A, Miao, H, Michaloliakos, I, Michel, C, Middleton, H, Milano, L, Miller, A, Millhouse, M, Mills, J, Milotti, E, Milovich-Goff, M, Minazzoli, O, Minenkov, Y, Mishkin, A, Mishra, C, Mistry, T, Mitra, S, Mitrofanov, V, Mitselmakher, G, Mittleman, R, Mo, G, Mogushi, K, Mohapatra, S, Mohite, S, Molina-Ruiz, M, Mondin, M, Montani, M, Moore, C, Moraru, D, Morawski, F, Moreno, G, Morisaki, S, Mours, B, Mow-Lowry, C, Mozzon, S, Muciaccia, F, Mukherjee, A, Mukherjee, D, Mukherjee, S, Mukund, N, Mullavey, A, Munch, J, Muniz, E, Murray, P, Nagar, A, Nardecchia, I, Naticchioni, L, Nayak, R, Neil, B, Neilson, J, Nelemans, G, Nelson, T, Nery, M, Neunzert, A, Ng, K, Ng, S, Nguyen, C, Nguyen, P, Nichols, D, Nichols, S, Nissanke, S, Nocera, F, Noh, M, North, C, Nothard, D, Nuttall, L, Oberling, J, O'Brien, B, Oganesyan, G, Ogin, G, Oh, J, Oh, S, Ohme, F, Ohta, H, Okada, M, Oliver, M, Olivetto, C, Oppermann, P, Oram, R, O'Reilly, B, Ormiston, R, Ortega, L, O'Shaughnessy, R, Ossokine, S, Osthelder, C, Ottaway, D, Overmier, H, Owen, B, Pace, A, Pagano, G, Page, M, Pagliaroli, G, Pai, A, Pai, S, Palamos, J, Palashov, O, Palomba, C, Pan, H, Panda, P, Pang, P, Pankow, C, Pannarale, F, Pant, B, Paoletti, F, Paoli, A, Parida, A, Parker, W, Pascucci, D, Pasqualetti, A, Passaquieti, R, Passuello, D, Patricelli, B, Payne, E, Pearlstone, B, Pechsiri, T, Pedersen, A, Pedraza, M, Pele, A, Penn, S, Perego, A, Perez, C, Perigois, C, Perreca, A, Perries, S, Petermann, J, Pfeiffer, H, Phelps, M, Phukon, K, Piccinni, O, Pichot, M, Piendibene, M, Piergiovanni, F, Pierro, V, Pillant, G, Pinard, L, Pinto, I, Piotrzkowski, K, Pirello, M, Pitkin, M, Plastino, W, Poggiani, R, Pong, D, Ponrathnam, S, Popolizio, P, Porter, E, Powell, J, Prajapati, A, Prasai, K, Prasanna, R, Pratten, G, Prestegard, T, Principe, M, Prodi, G, Prokhorov, L, Punturo, M, Puppo, P, Purrer, M, Qi, H, Quetschke, V, Quinonez, P, Raab, F, Raaijmakers, G, Radkins, H, Radulesco, N, Raffai, P, Rafferty, H, Raja, S, Rajan, C, Rajbhandari, B, Rakhmanov, M, Ramirez, K, Ramos-Buades, A, Rana, J, Rao, K, Rapagnani, P, Raymond, V, Razzano, M, Read, J, Regimbau, T, Rei, L, Reid, S, Reitze, D, Rettegno, P, Ricci, F, Richardson, C, Richardson, J, Ricker, P, Riemenschneider, G, Riles, K, Rizzo, M, Robertson, N, Robinet, F, Rocchi, A, Rodriguez-Soto, R, Rolland, L, Rollins, J, Roma, V, Romanelli, M, Romano, R, Romel, C, Romero-Shaw, I, Romie, J, Rose, C, Rose, D, Rose, K, Rosinska, D, Rosofsky, S, Ross, M, Rowan, S, Rowlinson, S, Roy, P, Roy, S, Ruggi, P, Rutins, G, Ryan, K, Sachdev, S, Sadecki, T, Sakellariadou, M, Salafia, O, Salconi, L, Saleem, M, Samajdar, A, Sanchez, E, Sanchez, L, Sanchis-Gual, N, Sanders, J, Santiago, K, Santos, E, Sarin, N, Sassolas, B, Sathyaprakash, B, Sauter, O, Savage, R, Savant, V, Sawant, D, Sayah, S, Schaetzl, D, Schale, P, Scheel, M, Scheuer, J, Schmidt, P, Schnabel, R, Schofield, R, Schonbeck, A, Schreiber, E, Schulte, B, Schutz, B, Schwarm, O, Schwartz, E, Scott, J, Scott, S, Seidel, E, Sellers, D, Sengupta, A, Sennett, N, Sentenac, D, Sequino, V, Sergeev, A, Setyawati, Y, Shaddock, D, Shaffer, T, Shahriar, M, Sharma, A, Sharma, P, Shawhan, P, Shen, H, Shikauchi, M, Shink, R, Shoemaker, D, Shukla, K, Shyamsundar, S, Siellez, K, Sieniawska, M, Sigg, D, Singer, L, Singh, D, Singh, N, Singha, A, Singhal, A, Sintes, A, Sipala, V, Skliris, V, Slagmolen, B, Slaven-Blair, T, Smetana, J, Smith, J, Smith, R, Somala, S, Son, E, Soni, S, Sorazu, B, Sordini, V, Sorrentino, F, Souradeep, T, Sowell, E, Spencer, A, Spera, M, Srivastava, A, Srivastava, V, Staats, K, Stachie, C, Standke, M, Steer, D, Steinke, M, Steinlechner, J, Steinlechner, S, Steinmeyer, D, Stocks, D, Stops, D, Stover, M, Strain, K, Stratta, G, Strunk, A, Sturani, R, Stuver, A, Sudhagar, S, Sudhir, V, Summerscales, T, Sun, L, Sunil, S, Sur, A, Suresh, J, Sutton, P, Swinkels, B, Szczepanczyk, M, Tacca, M, Tait, S, Talbot, C, Tanasijczuk, A, Tanner, D, Tao, D, Tapai, M, Tapia, A, Martin, E, Tasson, J, Taylor, R, Tenorio, R, Terkowski, L, Thirugnanasambandam, M, Thomas, M, Thomas, P, Thompson, J, Thondapu, S, Thorne, K, Thrane, E, Tinsman, C, Saravanan, T, Tiwari, S, Tiwari, V, Toland, K, Tonelli, M, Tornasi, Z, Torres-Forne, A, Torrie, C, Tosta e Melo, I, Toyra, D, Trail, E, Travasso, F, Traylor, G, Tringali, M, Tripathee, A, Trovato, A, Trudeau, R, Tsang, K, Tse, M, Tso, R, Tsukada, L, Tsuna, D, Tsutsui, T, Turconi, M, Ubhi, A, Ueno, K, Ugolini, D, Unnikrishnan, C, Urban, A, Usman, S, Utina, A, Vahlbruch, H, Vajente, G, Valdes, G, Valentini, M, Vallisneri, M, van Bakel, N, van Beuzekom, M, van den Brand, J, Van Den Broeck, C, Vander-Hyde, D, van der Schaaf, L, Van Heijningen, J, van Veggel, A, Vardaro, M, Varma, V, Vass, S, Vasuth, M, Vecchio, A, Vedovato, G, Veitch, J, Veitch, P, Venkateswara, K, Venugopalan, G, Verkindt, D, Veske, D, Vetrano, F, Vicere, A, Viets, A, Vinciguerra, S, Vine, D, Vinet, J, Vitale, S, Vivanco, F, Vo, T, Vocca, H, Vorvick, C, Vyatchanin, S, Wade, A, Wade, L, Wade, M, Walet, R, Walker, M, Wallace, G, Wallace, L, Walsh, S, Wang, J, Wang, S, Wang, W, Wang, Y, Ward, R, Warden, Z, Warner, J, Was, M, Watchi, J, Weaver, B, Wei, L, Weinert, M, Weinstein, A, Weiss, R, Wellmann, F, Wen, L, Wessels, P, Westhouse, J, Wette, K, Whelan, J, Whiting, B, Whittle, C, Wilken, D, Williams, D, Williams, R, Williamson, A, Willis, J, Willke, B, Winkler, W, Wipf, C, Wittel, H, Woan, G, Woehler, J, Wofford, J, Wong, C, Wright, J, Wu, D, Wysocki, D, Xiao, L, Yamamoto, H, Yang, L, Yang, Y, Yang, Z, Yap, M, Yazback, M, Yeeles, D, Yu, H, Yuen, S, Zadrozny, A, Zanolin, M, Zelenova, T, Zendri, J, Zevin, M, Zhang, J, Zhang, L, Zhang, T, Zhao, C, Zhao, G, Zhou, M, Zhou, Z, Zhu, X, Zimmerman, A, Zucker, M, Zweizig, J, IoP (FNWI), Faculty of Science, Gravitation and Astroparticle Physics Amsterdam, Other Research IHEF (IoP, FNWI), Astroparticle Physics (IHEF, IoP, FNWI), Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), The LIGO Scientific Collaboration, The Virgo Collaboration, Arene, M., Becsy, B., Bustillo, J. C., Diaz, J. C., Castaneda, J., Cavaglia, M., Cerda-Duran, P., Cieslar, M., Cordero-Carrion, I., Canton, T. D., Dalya, G., D'Angelo, B., D'Antonio, S., Deleglise, S., D'Emilio, V., Diaz, M. C., D'Urso, D., Fronze, G., Garcia-Quiros, C., Ghosh, A., Gonzalez, G., Guixe, G., Hubner, M. T., Isac, J. -M., Kefelian, F., Kim, C., Krolak, A., Kumar, R., Luck, H., Hernandez, I. M., Magana-Sandoval, F., Marka, S., Marka, Z., Villa, E. M., Mukherjee, A., Muniz, E. A., O'Brien, B. D., Oram, R. J., O'Reilly, B., O'Shaughnessy, R., Perigois, C., Perries, S., Pinto, I., Purrer, M., Rana, J., Rosinska, D., Roy, S., Schonbeck, A., Szczepanczyk, M. J., Tapai, M., Martin, E. N. T. S., Torres-Forne, A., Toyra, D., Vasuth, M., Vicere, A., Vivanco, F. H., Wessels, P., Yu, H., Zadrozny, A. K., and Zadrozny, A.
- Subjects
Technology ,Gravitational Waves, Open Data, O1, O2, LIGO, Virgo ,Astronomy ,Strain measurement ,Gravitational Wave ,open data ,Data representation and management ,Gravitational Waves ,GWOSC ,Scientific databases ,gravitational waves ,01 natural sciences ,General Relativity and Quantum Cosmology ,Software ,Documentation ,DESIGN ,Open Data ,Computer software ,Data products ,LIGO ,QC ,12-AXIS VIBRATION ISOLATION ,media_common ,Settore FIS/01 ,0303 health sciences ,Gravitational effects ,BINARY MERGERS ,Computer Science Applications ,Open data ,[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,Open science ,Astrophysics - Instrumentation and Methods for Astrophysics ,data analysis method ,gr-qc ,media_common.quotation_subject ,Real-time computing ,FOS: Physical sciences ,O2 ,PUBLIC ADVANCED LIGO ,General Relativity and Quantum Cosmology (gr-qc) ,Gravity waves ,programming ,O1 ,03 medical and health sciences ,QA76.75-76.765 ,Dewey Decimal Classification::000 | Allgemeines, Wissenschaft::000 | Informatik, Wissen, Systeme::004 | Informatik ,SDG 17 - Partnerships for the Goals ,GWOSC, Scientific databases, Data representation and management, Gravitational Waves ,0103 physical sciences ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,010306 general physics ,GRAVITATIONAL-WAVE CATALOG ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,STFC ,Astrophysique ,030304 developmental biology ,Science & Technology ,business.industry ,Gravitational wave ,Virgo ,gravitational radiation ,RCUK ,Strain data ,Data-quality information ,Computer Science, Software Engineering ,gravitational radiation detector ,detector: sensitivity ,Scientific database ,monitoring ,VIRGO ,Sky ,gravitational radiation: emission ,Computer Science ,ddc:004 ,business ,astro-ph.IM - Abstract
Abbot, Rich, et al. (Virgo and MAGIC Collaboration), Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software., The authors gratefully acknowledge the support of the United States National Science Foundation (NSF) for the construction and operation of the LIGO Laboratory and Advanced LIGO as well as the Science and Technology Facilities Council (STFC) of the United Kingdom, the Max-Planck-Society (MPS), and the State of Niedersachsen/Germany for support of the construction of Advanced LIGO and construction and operation of the GEO600 detector. Additional support for Advanced LIGO was provided by the Australian Research Council. The authors gratefully acknowledge the Italian Istituto Nazionale di Fisica Nucleare (INFN), the French Centre National de la Recherche Scientifique (CNRS) and the Foundation for Fundamental Research on Matter supported by the Netherlands Organisation for Scientific Research, for the construction and operation of the Virgo detector and the creation and support of the EGO consortium. The authors also gratefully acknowledge research support from these agencies as well as by the Council of Scientific and Industrial Research of India, the Department of Science and Technology, India, the Science & Engineering Research Board (SERB), India, the Ministry of Human Resource Development, India, the Spanish Agencia Estatal de Investigación, the Vicepresidència i Conselleria d’Innovació, Recerca i Turisme and the Conselleria d’Educació i Universitat del Govern de les Illes Balears, the Conselleria d’Educació, Investigació, Cultura i Esport de la Generalitat Valenciana, the National Science Centre of Poland, the Swiss National Science Foundation (SNSF), the Russian Foundation for Basic Research, the Russian Science Foundation, the European Commission, the European Regional Development Funds (ERDF), the Royal Society, the Scottish Funding Council, the Scottish Universities Physics Alliance, the Hungarian Scientific Research Fund (OTKA), the Lyon Institute of Origins (LIO), the Paris Île-de-France Region, the National Research, Development and Innovation Office Hungary (NKFIH), the National Research Foundation of Korea, Industry Canada and the Province of Ontario through the Ministry of Economic Development and Innovation, the Natural Science and Engineering Research Council Canada, the Canadian Institute for Advanced Research, the Brazilian Ministry of Science, Technology, Innovations, and Communications, the International Center for Theoretical Physics South American Institute for Fundamental Research (ICTP-SAIFR), the Research Grants Council of Hong Kong, the National Natural Science Foundation of China (NSFC), the Leverhulme Trust, the Research Corporation, the Ministry of Science and Technology (MOST), Taiwan and the Kavli Foundation. The authors gratefully acknowledge the support of the NSF, STFC, INFN and CNRS for provision of computational resources.
- Published
- 2021
- Full Text
- View/download PDF
13. Female Military Officers Report a Desire for Menstrual Suppression During Military Training
- Author
-
Emily A Ricker, Amelia S. Barrett, Patricia A. Deuster, Sarah J. de la Motte, and Carl Goforth
- Subjects
Adult ,medicine.medical_specialty ,Future studies ,media_common.quotation_subject ,Premenstrual Syndrome ,Limited access ,Menstruation ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Humans ,Medicine ,030212 general & internal medicine ,Baseline (configuration management) ,Amenorrhea ,media_common ,030219 obstetrics & reproductive medicine ,business.industry ,Public Health, Environmental and Occupational Health ,General Medicine ,Military personnel ,Military Personnel ,Hormonal contraception ,Family medicine ,Military health ,Female ,Worry ,business - Abstract
Introduction Service women face female-specific challenges that present physiological and logistical burdens and may impact readiness. The stress of training can change menstrual patterns and symptoms, and limited access to hygienic, private facilities can hinder menstrual management. Therefore, suppressing menses with continuous hormonal contraception may be of interest. Materials and Methods The 9-item “Military Women’s Attitudes Toward Menstrual Suppression.” questionnaire was administered to female officers upon entry (baseline) and graduation (post) from a 6-month secondary training course. Respondents rated their attitudes about menstruation and the stress of training, the desire for menstrual suppression, and the logistical burden of menstruation on a 1 (strongly agree) through 5 (strongly disagree) scale. Wilcoxon Signed Rank Tests determined changes in the distribution of responses from baseline to post. Results Female officers (n = 108) completed baseline and post questionnaires (age 25.2 ± 0.3 years). At baseline, the majority disagreed/strongly disagreed that the stress of training “makes periods worse than usual” (n = 77, 71%), “increases menstrual symptoms and bleeding” (n = 77, 71%), or “magnifies premenstrual syndrome” (PMS; n = 69, 64%). Although 50% (n = 54) agreed/strongly agreed that “stopping periods while women are training is a good idea,” 37% (n = 40) disagreed/strongly disagreed. The majority agreed/strongly agreed that menstrual suppression would prevent “the worry about menstrual supplies” (n = 75, 70%) and “the inconvenience of having a period during training” (n = 69, 64%). Many agreed/strongly agreed that it is difficult to deal with periods during training because “there is no privacy” (n = 52, 48%), “the inability to find adequate facilities” (n = 70, 65%), and “the lack of opportunity to use adequate facilities” (n = 52, 48%). Opinions remained largely consistent from baseline to post. Conclusions The desire for menstrual suppression among service women during training is high. Military health care providers should be prepared to counsel service women about strategies to manage menstruation, including the efficacy of continuous hormonal contraception for menstrual suppression. Future studies investigating benefits or risks of continuous hormonal contraception for menstrual suppression in service women should inform the clinical recommendations.
- Published
- 2021
- Full Text
- View/download PDF
14. 'Crisis, Conspiracy, and Community in Evangelical Climate Denial'
- Author
-
Aaron Ricker
- Subjects
business.industry ,media_common.quotation_subject ,Media studies ,Identity (social science) ,Comics ,Denial ,Phenomenon ,Voting ,Mainstream ,Relevance (law) ,Sociology ,Social identity theory ,business ,media_common - Abstract
Statistically speaking, American Evangelical Christians are uniquely attracted to apocalyptic conspiracy theories when it comes to the topic of climate change. Since Evangelicals constitute a powerful voting/lobbying/shopping bloc, it is worth asking why this might be the case and what (if anything) can be done about it. To this end, my study considers the relevance of two major cultural tributaries to American Evangelical pop apocalyptic culture. In the first section I consider biblical apocalyptic culture and argue that the characteristic apocalyptic promise to disclose hidden divine plans to a misunderstood but soon-tobe- vindicated elect group naturally entails conspiracy-theory thinking. I argue further that apocalyptic imagination and conspiracy-theory thinking are powerful tools for the definition of identity and community. In the second section I turn my attention to the kind of Evangelical pop apocalyptic culture that helped push climate science denial into the Christian mainstream. I argue that in pop apocalyptic productions like the influential tracts and comics of Jack T. Chick, the image of the elect as the persecuted and powerful bearers of special knowledge found a new lease on life, and continues to fascinate millions with the attractive offer of somebody special to be and somewhere special to belong. I conclude that apocalyptic questions of crisis and conspiracy have a sociological function, as means to the end of defining social identity. Understanding this concrete function of conspiracy-theory thinking in Christian apocalyptic imagination can help in assessing and addressing the troubling phenomenon of Evangelical climate denial.
- Published
- 2020
- Full Text
- View/download PDF
15. Inhibition of poly(ADP-ribose) polymerase induces synthetic lethality in BRIP1 deficient ovarian epithelial cells
- Author
-
Stephen B. Gruber, Gregory Idos, Marilena Melas, Koji Matsuo, Marcia A. Ciccone, Lynda D. Roman, Julie O. Culver, Charles M. Bowen, Kevin J. McDonnell, Asaf Maoz, Crystal L. Adams, Charité Ricker, Anand D. Jeyasekharan, and Teena Thakur
- Subjects
0301 basic medicine ,endocrine system diseases ,Cell Survival ,Poly ADP ribose polymerase ,CHO Cells ,Synthetic lethality ,Poly(ADP-ribose) Polymerase Inhibitors ,Article ,Piperazines ,Carboplatin ,Olaparib ,03 medical and health sciences ,chemistry.chemical_compound ,Cricetulus ,0302 clinical medicine ,Antineoplastic Combined Chemotherapy Protocols ,Animals ,Humans ,Medicine ,Molecular Targeted Therapy ,Viability assay ,Precision Medicine ,Cell Proliferation ,Ovarian Neoplasms ,Cisplatin ,BRCA1 Protein ,business.industry ,Recombinational DNA Repair ,Obstetrics and Gynecology ,Drug Synergism ,medicine.disease ,Fanconi Anemia Complementation Group Proteins ,030104 developmental biology ,Oncology ,chemistry ,030220 oncology & carcinogenesis ,PARP inhibitor ,Cancer research ,Phthalazines ,Female ,Synthetic Lethal Mutations ,business ,Ovarian cancer ,RNA Helicases ,medicine.drug - Abstract
Objective Pathogenic variations in the homologous recombination (HR) gene, BRCA1 interacting protein C-terminal helicase 1 (BRIP1) increase the risk for ovarian cancer. PARP inhibitors (PARPi) exert a synthetic lethal effect in BRCA-mutated ovarian cancers. Effective HR requires cooperation between BRCA1 and BRIP1; therefore, BRIP1-incompetancy may predict vulnerability to synthetic lethality. Here we investigated the response of ovarian epithelial cells with defective BRIP1 function to PARPi, and compared these cells to those lacking BRCA1 activity. Methods We engineered Chinese Hamster ovarian (CHO) epithelial cells to express deficient BRIP1 or BRCA1, and exposed them to olaparib with or without carboplatin or cisplatin. We assessed cellular proliferation and survival; we calculated inhibitory concentrations and combination and reduction drug indices. Results BRIP1 and BRCA1 inactivation impedes HR activity, decreases cellular proliferation and compromises DNA damage recovery. Platinum agent exposure impairs cellular survival. Olaparib exposure alone decreases cell viability in BRCA1-deficient cells, although has no effect on BRIP1-deficient cells. Combining carboplatin or cisplatin with olaparib synergistically attenuates cellular survival, consistent with synthetic lethality. Conclusions BRIP1-deficient ovarian epithelial cells exhibit defective HR, resulting in synthetic lethality when exposed to a platinum agent/PARPi combination. PARPi alone had no effect; this lack of effect may result from distinguishing molecular properties of BRIP1and/or consequences of genomic background. Our study identifies altered BRIP1 as a target for precision medicine-based therapies for ovarian cancers. This investigation supports consideration of the use of a platinum agent/PARPi combination in ovarian cancers depending upon genetic profile and genomic background.
- Published
- 2020
- Full Text
- View/download PDF
16. PD-1 inhibition therapy for advanced cutaneous squamous cell carcinoma: a retrospective analysis from the University of Southern California
- Author
-
Hossein Jadvar, Gino K. In, Mark S. Swanson, Jenny Hu, Brittney DeClerck, Poorva Vaidya, David J Hermel, Niels Kokot, Ashley Wysong, Alicia M. Terando, Lawrence R. Menendez, Kevin King, Gene Kim, William W. Tseng, Charité Ricker, David Peng, Kimberly A. Miller, Julie E. Lang, Omar Ragab, and Alexandra Filkins
- Subjects
0301 basic medicine ,Oncology ,Cancer Research ,medicine.medical_specialty ,Cutaneous squamous cell carcinoma ,Hematology ,business.industry ,medicine.medical_treatment ,Locally advanced ,General Medicine ,Disease ,Immunotherapy ,medicine.disease ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,Retrospective analysis ,Skin cancer ,Adverse effect ,business - Abstract
Approximately 5% of patients with cutaneous squamous cell carcinoma (CSCC) may develop recurrent or metastatic disease. The management of such cases is challenging and requires multi-disciplinary care. Immunotherapy using PD-1 inhibition was approved to treat unresectable or metastatic CSCC in 2018. Given limited data regarding clinical outcomes outside of published trials, we describe our experience using this therapy. We retrospectively reviewed all patients treated with PD-1 inhibition as therapy for locally advanced, regionally metastatic or distant metastatic CSCC at the University of Southern California. Clinicopathological characteristics, treatment data using PD-1 inhibitors, and outcomes were assessed. Among 26 patients treated with PD-1 inhibition, the objective response rate was 42.3%, with 19.2% of patients having partial response and 23.1% having complete response to therapy. The median progression-free survival was 5.4 months. Median tumor mutational burden (TMB) was higher among responders compared to non-responders (60 vs. 9 Mut/Mb, p = 0.04). Primary CSCC tumor location on the head/neck was also associated with response to PD-1 inhibition (p = 0.04). Two patients with mutations affecting mismatch repair deficiency were noted to have complete response to treatment. No other variables were associated with treatment outcomes. PD-1 inhibition produces durable responses among patients with advanced or metastatic CSCC. PD-1 inhibition therapy is well tolerated, but patients should be monitored closely for immune-related adverse events, particularly frail or immune-suppressed patients. Further investigation of potential biomarkers to help identify patients who will derive the most benefit from this therapeutic option is needed.
- Published
- 2020
- Full Text
- View/download PDF
17. Cost-effectiveness of balloon kyphoplasty and vertebroplasty versus conservative medical management in the USA
- Author
-
C I Nichols-Ricker, Thomas J. Hopkins, M Quinn, and S Eggington
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Cost effectiveness ,Cost-Benefit Analysis ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Context (language use) ,Medicare ,Balloon ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Fractures, Compression ,medicine ,Humans ,Kyphoplasty ,health care economics and organizations ,Aged ,Vertebroplasty ,business.industry ,Vertebral compression fracture ,Hazard ratio ,medicine.disease ,United States ,Treatment Outcome ,Relative risk ,Emergency medicine ,Orthopedic surgery ,Quality of Life ,Spinal Fractures ,Female ,030101 anatomy & morphology ,business ,Osteoporotic Fractures - Abstract
The cost-effectiveness of surgical versus conservative medical management of vertebral compression fractures in the US was analyzed in the context of inpatient versus outpatient treatment. Surgical intervention (balloon kyphoplasty and vertebroplasty) was found to be cost-effective relative to conservative medical management at a US willingness-to-pay threshold. To date, only one published study has evaluated the cost-effectiveness (C/E) of balloon kyphoplasty (BKP) or vertebroplasty (VP) in US Medicare patients with osteoporotic vertebral compression fractures. This study further evaluates the C/E of surgical treatment vs. conservative medical management (CMM), expanding on prior modeling by accounting for quality-adjusted life-years gained. A Markov microsimulation model of 1000 patients was constructed. Cost data were based on an analysis of Medicare claims payments, with propensity-score matching performed for BKP and VP vs. controls (CMM). Mortality inputs were based on US life tables, modified to account for age at initial fracture, presence of subsequent fracture(s), and relative risk of mortality by treatment. Separate incremental cost-effectiveness ratios (ICERs) were calculated for BKP and VP in inpatient and outpatient surgical treatment locations to account for individual clinical profiles presenting to each. The discounted ICER for inpatient BKP vs. CMM was $43,455 per QALY gained; for outpatient BKP vs. CMM, $10,922; for inpatient VP vs. CMM, $39,774; and for outpatient VP vs. CMM, $12,293. Probabilistic sensitivity analysis confirmed that both BKP and VP would be considered C/E vs. CMM at a US willingness-to-pay (WTP) threshold of $50,000/QALY in 80% and 100% of 500 model simulations, respectively. The most sensitive parameters included quality of life estimates and hazard ratios for mortality. While VP and BKP are more expensive treatment options than CMM in the short term, model results suggest interventional treatment is cost-effective, among patients eligible for surgery, at a US WTP threshold. This conclusion supports those from economic analyses conducted in EU-member countries.
- Published
- 2020
- Full Text
- View/download PDF
18. ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer
- Author
-
Steven P. Balk, Shahrzad Rafiei, William C. Hahn, Mu Yan Cai, Haitham Elmarakeby, Eliezer M. Van Allen, David Liu, Kenyon Fitzpatrick, Kent W. Mouw, Cora A. Ricker, Justin H. Hwang, Atish D. Choudhury, Bose Kochupurakkal, and Jihye Park
- Subjects
Male ,Cancer Research ,DNA Repair ,DNA repair ,DNA damage ,business.industry ,Kinase ,Poly ADP ribose polymerase ,Prostatic Neoplasms ,Ataxia Telangiectasia Mutated Proteins ,Poly(ADP-ribose) Polymerase Inhibitors ,medicine.disease ,Poly (ADP-Ribose) Polymerase Inhibitor ,Article ,body regions ,Prostate cancer ,medicine.anatomical_structure ,Oncology ,Prostate ,PARP inhibitor ,Cancer research ,medicine ,Humans ,business - Abstract
Alterations in DNA damage response (DDR) genes are common in advanced prostate tumors and are associated with unique genomic and clinical features. ATM is a DDR kinase that has a central role in coordinating DNA repair and cell-cycle response following DNA damage, and ATM alterations are present in approximately 5% of advanced prostate tumors. Recently, inhibitors of PARP have demonstrated activity in advanced prostate tumors harboring DDR gene alterations, particularly in tumors with BRCA1/2 alterations. However, the role of alterations in DDR genes beyond BRCA1/2 in mediating PARP inhibitor sensitivity is poorly understood. To define the role of ATM loss in prostate tumor DDR function and sensitivity to DDR-directed agents, we created a series of ATM-deficient preclinical prostate cancer models and tested the impact of ATM loss on DNA repair function and therapeutic sensitivities. ATM loss altered DDR signaling, but did not directly impact homologous recombination function. Furthermore, ATM loss did not significantly impact sensitivity to PARP inhibition but robustly sensitized to inhibitors of the related DDR kinase ATR. These results have important implications for planned and ongoing prostate cancer clinical trials and suggest that patients with tumor ATM alterations may be more likely to benefit from ATR inhibitor than PARP inhibitor therapy. Significance: ATM loss occurs in a subset of prostate tumors. This study shows that deleting ATM in prostate cancer models does not significantly increase sensitivity to PARP inhibition but does sensitize to ATR inhibition. See related commentary by Setton and Powell, p. 2085
- Published
- 2020
- Full Text
- View/download PDF
19. Self-reported Exposure to Sexual and Reproductive Health Information among American Indian Youth: Implications for Technology Based Intervention
- Author
-
Elizabeth Rink, Michael Anastario, Shannon Holder, Paula FireMoon, and Adriann Ricker
- Subjects
Male ,Gerontology ,Technology ,Health (social science) ,Adolescent ,Sexual Behavior ,Psychological intervention ,Library and Information Sciences ,Article ,Risk-Taking ,Surveys and Questionnaires ,Intervention (counseling) ,Humans ,Students ,American Indian or Alaska Native ,Reproductive health ,Consumer Health Information ,business.industry ,Communication ,Public Health, Environmental and Occupational Health ,Reproductive Health ,Female ,Intergenerational communication ,Self Report ,Smartphone ,Sexual Health ,business ,Psychology - Abstract
While technology-based interventions show promise in certain populations of American youth, the technology may intrinsically widen intergenerational communication chasms associated with youth's increased access to Smartphone technologies. The authors examined self-reported exposure to sexual and reproductive health information and evaluated its relationship with sexual risk behaviors with American Indian youth. Approximately 296 students, ages of 15-18 years old, were surveyed to examine self-reported exposure and attitudes to information received about sexual intercourse, reproduction, and social media use in relation to sexual risk behaviors. Results indicate that information received regarding sexual intercourse and birth control from intra-familial network members was associated with more engagement in sex, and that increased social media use to talk or learn about sex was associated with not using a condom at the last sexual encounter. We advise that researchers and programmers considering technology-based interventions with AI communities carefully consider the gravity of investing preventive resources into technology-based interventions that may further deepen communication gaps that youth experience within their community networks.
- Published
- 2020
- Full Text
- View/download PDF
20. The Prevent Ovarian Cancer Program (POCP): Identification of Women at Risk for Ovarian Cancer Using Complementary Recruitment Approaches
- Author
-
Jeanna M. McCuaig, Natalie Stickle, Tracy Stockley, Talin Boghosian, Tong Zhang, Raymond H. Kim, Alexandra Volenik, Rochelle Demsky, Nicole Ricker, Alicia A. Tone, Terri Stuart-McEwan, Patricia Shaw, Sarah E. Ferguson, Taymaa May, Suzanne Kamel-Reid, Carl Virtanen, Amit M. Oza, Marcus Q. Bernardini, Susan Armel, Stephane Laframboise, and Tina Romagnuolo
- Subjects
0301 basic medicine ,Adult ,Oncology ,medicine.medical_specialty ,Next of kin ,Adolescent ,Genetic counseling ,Carcinoma, Ovarian Epithelial ,Cohort Studies ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Risk Factors ,Internal medicine ,medicine ,Humans ,Genetic Predisposition to Disease ,Genetic Testing ,Prospective Studies ,First-degree relatives ,Aged ,Genetic testing ,Aged, 80 and over ,Ontario ,Ovarian Neoplasms ,medicine.diagnostic_test ,business.industry ,Patient Selection ,Obstetrics and Gynecology ,Mean age ,General Medicine ,Middle Aged ,medicine.disease ,Large cohort ,Serous fluid ,030104 developmental biology ,Direct targeting ,030220 oncology & carcinogenesis ,Practice Guidelines as Topic ,Ovarian carcinomas ,Female ,Ovarian cancer ,business - Abstract
Up to 20% of high-grade serous ovarian carcinomas (HGSOC) are hereditary; however, historical uptake of genetic testing is low. We used a unique combination of approaches to identify women in Ontario, Canada, with a first-degree relative (FDR) who died from HGSOC without prior genetic testing, and offer them multi-gene panel testing.From May 2015-Sept 2019, genetic counseling and testing was provided to eligible participants. Two recruitment strategies were employed, including self-identification in response to an outreach campaign and direct targeting of FDRs of deceased HGSOC patients treated at our institution. The rate of pathogenic variants (PV) in established/potential ovarian cancer risk genes and the benefits/challenges of each approach were assessed.A total of 564 women enrolled in response to our outreach campaign (n = 473) or direct recruitment (n = 91). Mean age at consent was 52 years and 96% did not meet provincial testing criteria. Genetic results were provided to 528 individuals from 458 families. The rate of PVs in ovarian cancer risk genes was highest when FDRs were diagnosed with HGSOC60 years (9.4% vs. 3.9% ≥ 60y, p = 0.0160). Participants in the outreach vs. direct recruitment cohort had a similar rate of PVs; however, uptake of genetic testing (97% vs. 89%; p = 0.0036) and study completion (95% vs. 87%; p = 0.0062) rates were higher in the former. Eleven participants with pathogenic variants have completed risk-reducing gynecologic surgery, with one stage I HGSOC and two breast cancers identified.Overall PV rates in this large cohort were lower than expected; however, we provide evidence that genetic testing criteria in Ontario should include individuals with a deceased FDR diagnosed with HGSOC60 years of age.
- Published
- 2021
- Full Text
- View/download PDF
21. Commentary in Response to 'A Review of Nonpharmacological Strategies in the Treatment of Relative Energy Deficiency in Sport'
- Author
-
Nicole C.A. Strock, Emily A Ricker, and Kristen J. Koltun
- Subjects
Gerontology ,Nutrition and Dietetics ,business.industry ,MEDLINE ,Medicine (miscellaneous) ,General Medicine ,Text mining ,Humans ,Relative Energy Deficiency in Sport ,Medicine ,Orthopedics and Sports Medicine ,business ,Sports ,Relative energy - Published
- 2021
- Full Text
- View/download PDF
22. Making Agricultural Input Subsidies More Effective and Profitable in Africa
- Author
-
Jacob Ricker-Gilbert, Charles B.L. Jumbe, and Joseph Kanyamuka
- Subjects
Natural resource economics ,Agriculture ,business.industry ,Subsidy ,Business - Abstract
The combined effects of declining soil fertility, continuous mono-cropping, poor crop residues management, and limited resources are considered the major constraints to increased crop productivity in Sub-Saharan Africa. It is for this reason that most African governments in Sub-Saharan Africa have been implementing farm input support programmes to boost smallholder production. While substantial amounts of resources are committed to support such programmes, evidence suggests that the increased use of modern inputs such as inorganic fertilizers on the main staple food crops appear to be only marginally profitable or even unprofitable. There is a renewed realization that the use of fertilizer input alone to raise farm productivity is likely to be impeded, if sufficient attention is not given to complementary interventions such as integrated soil fertility management technologies and extension services. This chapter provides evidence from several African countries on the role of complementary interventions in enhancing profitability, effectiveness, and efficiency with which farm inputs such as inorganic fertilizer and improved seed are applied.
- Published
- 2022
- Full Text
- View/download PDF
23. King-Devick Test Performance and Cognitive Dysfunction after Concussion: A Pilot Eye Movement Study
- Author
-
Yuka Matsuzawa, Todd E. Hudson, Felicia Fraser, Ivan Selesnick, Weiwei Dai, Doria M. Gold, Steven Galetta, John Martone, Laura J. Balcer, Amanda Childs, John Ross Rizzo, Janet C. Rucker, Yuen Shan Christine Lee, and Joseph H. Ricker
- Subjects
medicine.medical_specialty ,Neurosciences. Biological psychiatry. Neuropsychiatry ,Audiology ,Article ,rapid automatized naming tasks ,cognitive dysfunction ,Concussion ,Memory span ,medicine ,Effects of sleep deprivation on cognitive performance ,Neuropsychological assessment ,inter-saccadic interval ,medicine.diagnostic_test ,Working memory ,business.industry ,General Neuroscience ,Eye movement ,Cognition ,medicine.disease ,saccades ,King-Devick ,concussion ,business ,Stroop effect ,RC321-571 - Abstract
(1) Background: The King-Devick (KD) rapid number naming test is sensitive for concussion diagnosis, with increased test time from baseline as the outcome measure. Eye tracking during KD performance in concussed individuals shows an association between inter-saccadic interval (ISI) (the time between saccades) prolongation and prolonged testing time. This pilot study retrospectively assesses the relation between ISI prolongation during KD testing and cognitive performance in persistently-symptomatic individuals post-concussion. (2) Results: Fourteen participants (median age 34 years; 6 women) with prior neuropsychological assessment and KD testing with eye tracking were included. KD test times (72.6 ± 20.7 s) and median ISI (379.1 ± 199.1 msec) were prolonged compared to published normative values. Greater ISI prolongation was associated with lower scores for processing speed (WAIS-IV Coding, r = 0.72, p = 0.0017), attention/working memory (Trails Making A, r = −0.65, p = 0.006) (Digit Span Forward, r = 0.57, p = −0.017) (Digit Span Backward, r= −0.55, p = 0.021) (Digit Span Total, r = −0.74, p = 0.001), and executive function (Stroop Color Word Interference, r = −0.8, p = 0.0003). (3) Conclusions: This pilot study provides preliminary evidence suggesting that cognitive dysfunction may be associated with prolonged ISI and KD test times in concussion.
- Published
- 2021
24. The Use of COVID-19 Vaccines in Patients with SLE
- Author
-
Anca Askanase, Yevgeniya Gartshteyn, Sean Inzerillo, Wei Tang, Shane Murray, Edd C Ricker, and Leila Khalili
- Subjects
medicine.medical_specialty ,COVID-19 Vaccines ,Disease ,Booster dose ,Mycophenolic acid ,Autoimmune Diseases ,Immune system ,Systemic lupus erythematosus ,Rheumatology ,Internal medicine ,Rheumatic Diseases ,medicine ,Humans ,Lupus Erythematosus, Systemic ,skin and connective tissue diseases ,Vaccines ,business.industry ,SARS-CoV-2 ,COVID-19 ,United States ,Vaccination ,Systemic Lupus Erythematosus (G Tsokos, Section Editor) ,Methotrexate ,Rituximab ,Immunosuppressive agents ,business ,medicine.drug - Abstract
Purpose of Review Three COVID-19 vaccines obtained emergency authorization from the Food and Drug Administration (FDA) and are widely used in the USA. Unfortunately, there is a paucity of evidence on the safety and efficacy of these vaccines in patients with autoimmune inflammatory rheumatic diseases (AIIRD), as these patients were excluded from all phases of vaccine development. Here we reviewed current data on COVID-19 vaccination in patients with AIIRD, with emphasis on systemic lupus erythematosus (SLE), and provided a comprehensive update on the benefits and risks of vaccination. Recent Findings Patients with SLE have worse immune responses following SARS-CoV-2 vaccination than healthy controls. The efficacy of the COVID-19 vaccines seems to be further reduced by immunosuppressive medications, such as glucocorticoids (GC), methotrexate (MTX), mycophenolate/mycophenolic acid (MMF), and rituximab (RTX). However, these data do not substantiate that AIIRD patients are at greater risk of disease flares or have a higher incidence of side effects following vaccination. There is no significant safety concern for the use of COVID-19 vaccines in patients with AIIRD. Summary The benefits of vaccination far outweigh the risks in patients with AIIRD, including SLE. More data are needed to determine the necessity of a booster vaccine dose and appropriate adjustment of immunosuppressants around the administration of vaccine.
- Published
- 2021
25. Estimated Cancer Risks Associated with Nitrosamine Contamination in Commonly Used Medications
- Author
-
Feng C. Tsai, Kate Li, M. Elizabeth Marder, Karin Ricker, Martha S. Sandy, Sarah Elmore, Meng Sun, Rose Schmitz, Gwendolyn Osborne, and ChingYi J. Hsieh
- Subjects
Drug ,Nitrosamines ,Health, Toxicology and Mutagenesis ,media_common.quotation_subject ,Dimethylnitrosamine ,Food and drug administration ,chemistry.chemical_compound ,Environmental health ,Neoplasms ,Medicine ,cancer ,Animals ,Diethylnitrosamine ,Animal species ,Carcinogen ,media_common ,business.industry ,Communication ,Public Health, Environmental and Occupational Health ,Cancer ,risk assessment ,Contamination ,medicine.disease ,chemistry ,Diabetes Mellitus, Type 2 ,Nitrosamine ,Carcinogens ,business ,Risk assessment - Abstract
Many nitrosamines are potent carcinogens, with more than 30 listed under California’s Proposition 65. Recently, nitrosamine contamination of commonly used drugs for treatment of hypertension, heartburn, and type 2 diabetes has prompted numerous Food and Drug Administration (FDA) recalls in the US. These contaminants include the carcinogens NDMA (N-nitrosodimethylamine) and NDEA (N-nitrosodiethylamine) and the animal tumorigen NMBA (N-nitroso-N-methyl-4-aminobutyric acid). NMBA and NDEA are metabolically and/or structurally related to NDMA, an N-nitrosomethyl-n-alkylamine (NMA), and 12 other carcinogenic NMAs. These nitrosamines exhibit common genotoxic and tumorigenic activities, with shared target tumor sites amongst chemicals and within a given laboratory animal species. We use the drug valsartan as a case study to estimate the additional cancer risks associated with NDMA and NDEA contamination, based on nitrosamine levels reported by the US FDA, cancer potencies developed by California’s Proposition 65 program and the US Environmental Protection Agency (EPA), and specific exposure scenarios. These estimates suggest that nitrosamine contamination in drugs that are used long-term can increase cancer risks and pose a serious concern to public health.
- Published
- 2021
26. Safety of tetanus, diphtheria, and acellular pertussis vaccination among pregnant active duty U.S. military women
- Author
-
Zeina G. Khodr, Gia R. Gumbs, Clinton Hall, Ava Marie S Conlin, Lisa M. Abramovitz, Ashley A. Ricker, Natalie Y. Wells, and Anna T Bukowinski
- Subjects
medicine.medical_specialty ,Whooping Cough ,Population ,Abortion ,Diphtheria-Tetanus-acellular Pertussis Vaccines ,Congenital Abnormalities ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,030225 pediatrics ,medicine ,Humans ,030212 general & internal medicine ,education ,education.field_of_study ,Tetanus ,General Veterinary ,General Immunology and Microbiology ,Obstetrics ,business.industry ,Diphtheria ,Vaccination ,Infant, Newborn ,Public Health, Environmental and Occupational Health ,Infant ,Infant, Low Birth Weight ,medicine.disease ,Pregnancy Complications ,Pregnancy Trimester, First ,Low birth weight ,Military Personnel ,Infectious Diseases ,Maternal Exposure ,Premature Birth ,Molecular Medicine ,Gestation ,Female ,medicine.symptom ,business - Abstract
Background The tetanus, diphtheria, and acellular pertussis (Tdap) vaccine was approved for U.S. adults in 2005 and recommended for administration in every pregnancy in 2012, with optimal timing between 27 and 36 weeks’ gestation. In the military, however, a current Tdap vaccination status is compulsory for service, and active duty women may be inadvertently exposed in early pregnancy. Safety data in this population are limited. Objectives To assess safety of inadvertent (0–13 weeks’ gestation) and recommended (27–36 weeks’ gestation) exposure to the Tdap vaccine in pregnancy. Methods Pregnancies and live births from Department of Defense Birth and Infant Health Research program data were linked with military personnel immunization records to determine pregnancy Tdap vaccine exposure among active duty women, 2006–2014. Multivariable Cox and generalized linear regression models estimated associations between Tdap vaccine exposure and adverse pregnancy or infant outcomes. Results Of 145,883 pregnancies, 1272 were exposed to the Tdap vaccine in the first trimester and 9438 between 27 and 36 weeks’ gestation. Neither inadvertent nor recommended vaccine exposure were associated with spontaneous abortion, preeclampsia, or preterm labor. Among 117,724 live born infants, 984 were exposed to the Tdap vaccine in the first trimester and 9352 between 27 and 36 weeks’ gestation. First trimester exposure was not associated with birth defects, growth problems in utero, growth problems in infancy, preterm birth, or low birth weight. Tdap vaccine exposure between 27 and 36 weeks’ gestation was not associated with any adverse infant outcome. Conclusions Among a population of active duty women in the U.S. military who received the Tdap vaccine during pregnancy, we detected no increased risks for adverse maternal, fetal, or infant outcomes. Our findings corroborate existing literature on the safety of exposure to the Tdap vaccine in pregnancy.
- Published
- 2020
- Full Text
- View/download PDF
27. How do informal farmland rental markets affect smallholders’ well‐being? Evidence from a matched tenant–landlord survey in Malawi
- Author
-
Joseph Kanyamuka, Rodney Lunduka, Jacob Ricker-Gilbert, Jordan Chamberlin, Charles B.L. Jumbe, and Stevier Kaiyatsa
- Subjects
Economics and Econometrics ,Labour economics ,business.industry ,media_common.quotation_subject ,05 social sciences ,Equity (finance) ,Renting ,Cash ,0502 economics and business ,Well-being ,050202 agricultural economics & policy ,Landlord ,Business ,050207 economics ,Agronomy and Crop Science ,media_common - Abstract
We estimate the efficiency and equity returns to farmland rental markets in Malawi using a matched tenant–landlord survey of smallholder farm households in four districts. Our sample allows us to more fully observe the landlord side of the rental market, which is almost always missing in previous studies. Our results suggest that land rental markets promote efficiency by facilitating a net transfer of land to more productive farmers. We also find that land rental markets promote equity as conventionally defined in the land markets literature, that is, by transferring land from land‐rich households to land‐poor households, and from labor‐poor to labor‐rich households. However, our study identifies some important challenges for land rental markets in this context. First, we find that tenants in our sample are wealthier than their landlord counterpart on average in all dimensions other than landholding. In addition, most landlords report the motive for renting out their land as either the need for immediate cash, or the lack of labor and/or capital to cultivate the plot that was rented out. These findings align with concerns about potential “stress renting” by poor landlords and suggest the value of defining equity along a broader set of dimensions other than simply equalizing the distribution of farmland and labor.
- Published
- 2019
- Full Text
- View/download PDF
28. Food Safety and Adverse Selection in Rural Maize Markets
- Author
-
Jacob Ricker-Gilbert, Didier Kadjo, Gerald Shively, and Tahirou Abdoulaye
- Subjects
Economics and Econometrics ,media_common.quotation_subject ,Adverse selection ,Food storage ,Context (language use) ,Agricultural science ,Information asymmetry ,asymmetric information ,0502 economics and business ,C13 ,Quality (business) ,D13 ,050207 economics ,media_common ,O33 ,Pesticide residue ,O12 ,business.industry ,05 social sciences ,O39 ,Food safety ,Agricultural and Biological Sciences (miscellaneous) ,food safety ,Original Article ,050202 agricultural economics & policy ,Business ,Food quality - Abstract
Without enforced standards or reliable third‐party verification, food safety threats such as pesticide residues and aflatoxin contamination are generally unobservable or only partially observable to both buyers and sellers, especially of staple foods in rural maize markets in sub‐Saharan Africa. As a result, sellers have more information about food quality than do buyers. Such information asymmetries can impede market development and undermine human health. We study farm household behaviour in the context of imperfect food safety information. We pool observations obtained from 707 food storage containers maintained by 309 farm households in Benin, surveyed following the maize harvests of 2011/2012 and 2013/2014. Our results indicate that when a household perceives a food safety risk associated with application of insecticides, on average it is 33 percentage points less likely to apply insecticides to maize it intends to consume than it is to maize it intends to sell. These individuals are also more likely to sell maize than households without food safety concerns. Results highlight the potential value of improved storage technologies and quality control to promote market transactions and reduce hidden health risks.
- Published
- 2019
29. Pathogenic and likely pathogenic variants in PALB2 , CHEK2 , and other known breast cancer susceptibility genes among 1054 BRCA -negative Hispanics with breast cancer
- Author
-
Nancy Feldman, Aaron Adamson, Sharon Sand, Charité Ricker, Thomas P. Slavin, Christopher A. Haiman, Scott Huntsman, Jeffrey N. Weitzel, Amie Blanco, Susan L. Neuhausen, Danielle Castillo, Shu Tao, Donglei Hu, Linda Steele, Asaf Maoz, Gary Unzeitig, Bita Nehoray, Elad Ziv, and Margalit Rosenblatt
- Subjects
Oncology ,Cancer Research ,medicine.medical_specialty ,education.field_of_study ,business.industry ,PALB2 ,Population ,Cancer ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,030212 general & internal medicine ,skin and connective tissue diseases ,Ovarian cancer ,business ,education ,CHEK2 ,Exome sequencing ,Founder effect - Abstract
BACKGROUND Breast cancer (BC) is the most common cancer and related cause of mortality among Hispanics, yet susceptibility has been understudied. BRCA1 and BRCA2 (BRCA) mutations explain less than one-half of hereditary BC, and the proportion associated with other BC susceptibility genes is unknown. METHODS Germline DNA from 1054 BRCA-mutation-negative Hispanic women with hereditary BC (BC diagnosed at age C PV (1.32%). CONCLUSIONS Of 1054 BRCA-negative, high-risk Hispanic women, 4.5% carried a PV in a cancer susceptibility gene, increasing understanding of hereditary BC in this population. Recurrent PVs in PALB2 and CHEK2 represented 47% (23 of 49) of the total, suggesting a founder effect. Accurate classification of variants was enabled by carefully controlling for ancestry and the increased identification of at-risk Hispanics for screening and prevention.
- Published
- 2019
- Full Text
- View/download PDF
30. What drives smallholder farmers’ willingness to pay for a new farm technology? Evidence from an experimental auction in Kenya
- Author
-
Dan J. Stein, Jacob Ricker-Gilbert, Hira Channa, Patricia Pina, and Amy Z. Chen
- Subjects
Price elasticity of demand ,Economics and Econometrics ,Sociology and Political Science ,Agricultural machinery ,business.industry ,Subsidy ,Experimental auction ,Management, Monitoring, Policy and Law ,Development ,Kenya ,Article ,Profit (economics) ,Agricultural science ,Willingness to pay ,Incentive compatibility ,Business ,Hermetic storage ,Dissemination ,Medium of information ,Food Science ,Valuation (finance) - Abstract
Highlights • Demand among smallholder farmers in Kenya for improved storage bags is elastic. • Lowering the price of the bag by 20% leads to a 29% increase in profit. • Prior awareness of the technology increases mean willingness to pay by 20%. • Medium by which information is disseminated does not affect willingness to pay. • Cheapest media option, text message, is most cost-effective., We use an incentive compatible experimental auction to measure demand for a new agricultural technology, a triple layered hermetic storage bag. When used properly, the bag creates an airtight seal that reduces storage loss from insect pests and neutralizes aflatoxin contamination in stored grain. We find that demand for this new technology is highly elastic (4.3) and that the wholesaler could increase profit by lowering the price. We also find that farmers’ valuation for the bag is not significantly different based on the medium through which information about it is communicated to them, either text, audio or video messages. This suggests that practitioners should use the cheapest option for disseminating information, which is text messaging in this context. In addition, we find that farmers who have prior awareness of the bag are willing to pay 20% more on average than those previously unaware of it. In total, the highly elastic demand for the improved bags, along with the fact that prior awareness of the bag leads to higher willingness to pay, suggests that a one-time price subsidy for the new technology could spur demand and increase future adoption.
- Published
- 2019
- Full Text
- View/download PDF
31. Whole New People of the Book
- Author
-
Aaron Ricker
- Subjects
People of the Book ,business.industry ,media_common.quotation_subject ,Art history ,Islam ,General Medicine ,Representation (arts) ,Art ,Comics ,business ,media_common - Abstract
A. David Lewis and Martin Lund, eds. 'Muslim Superheroes: Comics, Islam, and Representation'. Cambridge, MA: Harvard University Press, 2017. 264 pp., 15 illustrations. $24.95, paper.
- Published
- 2019
- Full Text
- View/download PDF
32. Breathe In, Breathe Out
- Author
-
Melissa Ashley Ricker, Peter Sandor, and Zachary Lavender
- Subjects
Mechanical ventilation ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,General Medicine ,Intensive care unit ,Hypoxemia ,law.invention ,law ,medicine ,Acute respiratory failure ,medicine.symptom ,Respiratory system ,Intensive care medicine ,business ,Hypercapnia - Published
- 2019
- Full Text
- View/download PDF
33. Burn Bright II: Reflections on Solutions to Burnout (Part Two of a Two-Part Series)
- Author
-
Mari Ricker and Noshene Ranjbar
- Subjects
Series (mathematics) ,business.industry ,Physicians ,Mathematics education ,Humans ,Medicine ,General Medicine ,Burnout ,business ,Burnout, Professional ,Delivery of Health Care - Published
- 2019
- Full Text
- View/download PDF
34. Fearful symmetry: revelation, Hellboy, and pop apocalyptic violence
- Author
-
Aaron Ricker
- Subjects
Literature ,business.industry ,media_common.quotation_subject ,Art ,Symmetry (geometry) ,business ,Revelation ,media_common - Published
- 2021
- Full Text
- View/download PDF
35. Diversity of Antibiotic Resistance genes and Transfer Elements-Quantitative Monitoring (DARTE-QM): a method for detection of antimicrobial resistance in environmental samples
- Author
-
Nicole Ricker, Heather K. Allen, Jinlyung Choi, Adina Howe, Schuyler D. Smith, Fan Yang, Shannon M. Hinsa-Leasure, and Michelle L. Soupir
- Subjects
Animal feces ,Antibiotic resistance ,business.industry ,Test performance ,Environmental systems ,Microbiome ,Biology ,business ,Biotechnology ,Antibiotic resistance genes - Abstract
Effective monitoring of antibiotic resistance genes and their dissemination in environmental ecosystems has been hindered by the cost and efficiency of methods available for the task. We developed a method entitled the Diversity of Antibiotic Resistance genes and Transfer Elements-Quantitative Monitoring (DARTE-QM), a system implementing high-throughput sequencing to simultaneously sequence thousands of antibiotic resistant genes representing a full-spectrum of antibiotic resistance classes commonly seen in environmental systems. In this study, we demonstrated DARTE-QM by screening 662 antibiotic resistance genes within environmental samples originated from manure, soil, and animal feces, in addition to a mock-community used as a control to test performance. DARTE-QM offers a new approach to studying antibiotic resistance in environmental microbiomes, showing advantages in efficiency and the ability to scale for many samples. This method provides a means of data acquisition that will alleviate the obstacles that many researchers in this area currently face.
- Published
- 2021
- Full Text
- View/download PDF
36. Development and pilot testing of a training for bilingual community education professionals about hereditary breast and ovarian cancer among Latinas: ÁRBOLES Familiares
- Author
-
Gwendolyn P. Quinn, Alejandra Hurtado-de-Mendoza, Lindsay Fuzzell, Katie Fiallos, Claudia Campos-Galvan, Jennifer Garcia, Susan T. Vadaparampil, Laura Moreno Botero, Marc Schwartz, Beth N. Peshkin, Charité Ricker, Lina Jandorf, Kristi D. Graves, and Katherine Lopez
- Subjects
0301 basic medicine ,Adult ,medicine.medical_specialty ,Community education ,Referral ,Genetic counseling ,media_common.quotation_subject ,Language barrier ,Breast Neoplasms ,Genetic Counseling ,030105 genetics & heredity ,Literacy ,03 medical and health sciences ,Behavioral Neuroscience ,0302 clinical medicine ,Health care ,medicine ,Humans ,Genetic Testing ,Applied Psychology ,media_common ,Ovarian Neoplasms ,Health Equity ,business.industry ,Hispanic or Latino ,Health equity ,Outreach ,030220 oncology & carcinogenesis ,Family medicine ,Female ,business ,Psychology - Abstract
Cancer health disparities remain a significant problem in the USA, compounded by lack of access to care, language barriers and systemic biases in health care. These disparities are particularly evident in areas such as genetics/genomics. For example, Latinas at high risk for hereditary breast and ovarian cancer (HBOC) have extremely low rates of genetic counseling/testing. Long-standing barriers and inequities in access to services such as genetic counseling and testing require innovative solutions. One solution can involve training community outreach and education professionals (CORE-Ps) to bridge the gap between underserved communities and genetic specialists. We sought to develop and pilot test a training program for English-Spanish bilingual CORE-Ps to reduce disparities in access to and uptake of genetic services among Latino populations. Guided by Adult Learning Theory and with input from multiple stakeholders, we developed ÁRBOLES Familiares (Family Trees), an in-person and online training program for bilingual CORE-Ps to facilitate identification, referral, and navigation of Latinas to genetic counseling/testing. We conducted a pilot test of 24 CORE-Ps recruited from across the United States and assessed knowledge, genetic literacy, and self-efficacy at baseline and follow-up. At follow-up, participants in the pilot with complete baseline and follow-up data (N = 15) demonstrated significant improvements in HBOC knowledge, genetic literacy, self-efficacy and reports of fewer barriers to identify/navigate Latinas (ps.05). Qualitative assessment identified ways to improve the training curriculum. Pilot results suggest ÁRBOLES is a promising approach for training CORE-Ps to identify and refer high-risk Latinas to genetic services. Next steps involve further refinement of ÁRBOLES, development of an online toolkit, and adaptation for virtual delivery.Latinas at high risk for hereditary breast and ovarian cancer (HBOC) have low rates of genetic counseling and testing. Latinas may not have ready access to services like genetic counseling and testing, which need special solutions. One solution can involve training community health workers to bridge the gap between Latinas and genetic specialists. We developed an online and in person training program (ÁRBOLES Familiares or Family Trees) for English-Spanish bilingual community health workers that teaches them how to help Latinas get access to genetic services. We tested this program with a small group of community health workers. After the program, their HBOC knowledge, genetic literacy, and confidence to help Latinas get access to genetic services had improved. Trainees also made suggestions to improve the program, which will be used to help future trainees expand their knowledge and skills to work with Latinas at risk of HBOC.
- Published
- 2021
37. Determination of the Material Properties of the Reinforcement for Textile-Reinforced Concrete Elements
- Author
-
Sergej Rempel, Marcus Ricker, and Tânia Feiri
- Subjects
Engineering ,business.industry ,Structural engineering ,Reinforcement ,business ,Material properties ,Textile-reinforced concrete - Abstract
Textile-reinforced concrete has emerged in recent years as a new and valuable construction material. The design of textile-reinforced concrete requires knowledge on the mechanical properties of different textile types as well as their reinforcing behaviour under different loading conditions. Conventional load-bearing tests tend to be complex, time-consuming, costly and can even lack consistent specifications. To mitigate such drawbacks, a standardised tensile test for fibre strands was developed aiming at characterising the material properties needed for the design of a textile-reinforced concrete component. For the sake of this study, an epoxy resin-soaked AR-glass reinforcement was considered. The standardised tensile test uses a fibre strand with 160 mm length, which shall be cut out of a textile grid. The results show that the textile reinforcement has a linear-elastic behaviour, and the ultimate tensile strength can be statistically modelled by a Gumbel distribution. Furthermore, the results indicate that the modulus of elasticity is not influenced by the length or the number of fibre strands. Therefore, the mean value from the standardised test can be used for the design purpose. These findings are essential to derive an appropriate partial safety factor for the calculation of the design values of the tensile strength and can be used to determine the failure probability of textile-reinforced concrete components.
- Published
- 2021
- Full Text
- View/download PDF
38. Increased burden of familial-associated early-onset cancer risk among minority Americans compared to non-Latino Whites
- Author
-
W. James Gauderman, Ivo S. Muskens, Adam J. de Smith, Lucy A. Godley, Qianxi Feng, Eric Nickels, Andrew D. Leavitt, Thomas M. Mack, Amy C. Yee, Joseph L. Wiemels, and Charité Ricker
- Subjects
0301 basic medicine ,Male ,Proband ,linked cancer registry ,Native Hawaiian or Other Pacific Islander ,Ethnic group ,global health ,California ,0302 clinical medicine ,Risk Factors ,Neoplasms ,Epidemiology ,Ethnicity ,Medicine ,Biology (General) ,familial risk ,Child ,Minority Groups ,Cancer ,Hispanic paradox ,General Neuroscience ,Incidence ,latino americans ,General Medicine ,Hispanic or Latino ,Mental Health ,hispanic paradox ,030220 oncology & carcinogenesis ,Child, Preschool ,Pacific islanders ,Female ,epidemiology ,Research Article ,Human ,Adult ,medicine.medical_specialty ,Adolescent ,QH301-705.5 ,Concordance ,Science ,Black People ,early-onset cancer ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,Young Adult ,Clinical Research ,Genetics ,Genetic predisposition ,Humans ,Genetic Predisposition to Disease ,human ,First-degree relatives ,Preschool ,General Immunology and Microbiology ,business.industry ,Prevention ,Infant, Newborn ,Infant ,race/ethnicity ,Newborn ,medicine.disease ,Confidence interval ,030104 developmental biology ,Epidemiology and Global Health ,Relative risk ,Biochemistry and Cell Biology ,business ,Demography - Abstract
BackgroundThe role of race/ethnicity in genetic predisposition of early-onset cancers can be estimated by comparing family-based cancer concordance rates among ethnic groups.MethodsWe used linked California health registries to evaluate the relative cancer risks for first degree relatives of patients diagnosed between ages 0-26, and the relative risks of developing distinct second primary malignancies (SPMs). From 1989-2015, we identified 29,631 cancer patients and 62,863 healthy family members. We calculated the standardized incident ratios (SIRs) of early-onset primary cancers diagnosed in proband siblings and mothers, as well as SPMs detected among early-onset patients. Analyses were stratified by self-identified race/ethnicity.ResultsGiven probands with cancer, there were increased relative risks of any cancer for siblings and mothers [SIR=3.32;95% confidence interval (CI):2.85-3.85)] and of SPMs (SIR=7.27;95%CI:6.56-8.03). Higher relative risk of any cancer in siblings and mothers given a proband with solid cancer (PConclusionsThe data support a need for increased attention to the genetics of early-onset cancer predisposition and environmental factors in race/ethnic minority families in the US.FundingThis work was supported by the V Foundation for funding this work (Grant FP067172).Key MessagesWe identified 29 631 cancer patients and their 62 863 healthy family members in California from 1989 to 2015.The risk of early-onset cancer in siblings and mothers was elevated by having a proband with cancer in the same family.The relative risk of early-onset cancers given a proband with solid cancer was higher for Latinos and Blacks when compared to non-Latino Whites.
- Published
- 2021
39. Transient Laser Energy Absorption, Co-axial Melt Pool Monitoring, and Relationship to Melt Pool Morphology
- Author
-
Richard E. Ricker, Brandon M. Lane, Ivan Zhirnov, Steven E. Grantham, Santosh Rauniyar, Kevin Chou, and Sergey Mekhontsev
- Subjects
0209 industrial biotechnology ,Materials science ,Fabrication ,business.industry ,Biomedical Engineering ,Photodetector ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Thermal conduction ,Laser ,Signal ,Industrial and Manufacturing Engineering ,Article ,law.invention ,020901 industrial engineering & automation ,Optics ,law ,Ultrafast laser spectroscopy ,General Materials Science ,Selective laser melting ,0210 nano-technology ,business ,Absorption (electromagnetic radiation) ,Engineering (miscellaneous) - Abstract
Melt pool monitoring (MPM) is a technique used in laser powder bed fusion (LPBF) to extract features from insitu sensor signals that correlate to defect formation or general part fabrication quality. Various melt pool phenomena have been shown to relate to measured transient absorption of the laser energy, which in turn, can be relatable to the melt pool emission measured in MPM systems. This paper describes use of a reflectometer-based instrument to measure the dynamic laser energy absorption during single-line laser scans. Scans are conducted on bare metal and single powder layer of nickel alloy 625 (IN625) at a range of laser powers. In addition, a photodetector aligned co-axially with the laser, often found in commercial LPBF monitoring systems, synchronously measured of the incandescent emission from the melt pool with the dynamic laser absorption. Relationships between the dynamic laser absorption, co-axial MPM, and surface features on the tracks are observed, providing illustration of the melt pool dynamics that formed these features. Time-integrated measurements of laser absorption are shown to correlate well with MPM signal, as well as indicate the transition between conduction and keyhole mode. This transition is corroborated by metallographic cross-section measurement, as well as topographic measurements of the solidified tracks. Ultimately, this paper exemplifies the utility of dynamic laser absorption measurements to inform both the physical nature of the melt pool dynamics, as well as interpretation of process monitoring signals.
- Published
- 2021
40. A Case Series of Multiple Primary Malignancies Among Patients With Advanced Melanoma
- Author
-
Varsha Tulpule, Irene Kang, Matthew Isaiah Ebia, Charité Ricker, Kimberly A. Miller, Anishka D'souza, Gino K. In, David R. Freyer, Jacob Stephen Thomas, and Stephen Capone
- Subjects
Oncology ,medicine.medical_specialty ,medicine.medical_treatment ,Dermatology ,Malignancy ,Internal medicine ,melanoma ,medicine ,cancer survival ,Thyroid cancer ,Survival analysis ,Tumor microenvironment ,business.industry ,Medical record ,Melanoma ,Thyroid ,General Engineering ,Immunotherapy ,medicine.disease ,multiple primary malignancies ,medicine.anatomical_structure ,hereditary cancer ,Preventive Medicine ,immunotherapy ,business - Abstract
Multiple primary malignancies (MPM) are described as two or more primary tumors within the same individual. The impact of MPM on the tumor microenvironment among patients with melanoma is poorly understood. Here, we describe this unique group of patients who have both advanced melanoma and at least one other primary malignancy and report their survival outcomes. In this study, patients with advanced melanoma and a second primary malignancy were identified. Medical records were reviewed for cancer treatment history. Kaplan-Meier methods were used to derive survival curves and estimate overall survival (OS), and log-rank tests were used to compare OS. Among 11 MPM patients, the most common non-melanoma cancers were breast (n = 3) and thyroid (n = 3). Median OS was 153.5 months for all patients. Median OS for synchronous MPM (sMPM) and metachronous MPM (mMPM) were 83.1 and 196.7 months, respectively (p= 0.10). Median OS was not reached when melanoma was diagnosed first, and 153.5 months when diagnosed second (p= 0.45). For six patients receiving immunotherapy for melanoma, there was a 100% complete response rate. In conclusion, patients with melanoma are at risk of secondary malignancies, including breast and thyroid cancer. The timing of secondary malignancies may impact prognosis. Further study of the impact of immunotherapy on MPM is warranted.
- Published
- 2021
- Full Text
- View/download PDF
41. Clinical and Electrophysiological Outcomes After Eye Muscle Surgery in 81 Adults With Infantile Nystagmus Syndrome
- Author
-
Ian Boydstun, Ferhat Evliyaoglu, Richard W. Hertle, Isabel Ricker, Ana Juric, and Molly Curtis
- Subjects
Adult ,medicine.medical_specialty ,Refractive error ,genetic structures ,Eye Movements ,media_common.quotation_subject ,Visual Acuity ,Nystagmus ,Nystagmus, Pathologic ,Ophthalmology ,Medicine ,Contrast (vision) ,Humans ,Prospective Studies ,Strabismus ,Child ,media_common ,business.industry ,Infantile nystagmus syndrome ,Infant ,General Medicine ,medicine.disease ,eye diseases ,Electrophysiology ,Oculomotor Muscles ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Albinism ,Optic nerve ,medicine.symptom ,business - Abstract
Purpose: To characterize the effects of eye muscle surgery on patients older than 18 years with infantile nystagmus syndrome (INS) who have had only optical treatment. Methods: This was a prospective, single-center, interventional case series analysis of clinical and electro-phyisological data before and after surgery. Outcome measures included: clinical characteristics, surgical procedure, and preoperative and postoperative binocular best corrected visual acuity (BCVA) in the null position, anomalous head posture (AHP), contrast sensitivity, strabismic deviation, and nystagmus acuity function (NAFX). Postoperative data used were collected for a minimum of 12 months after surgery. Parametric and non-parametric statistical analysis of the outcome measures was performed. Results: Ages ranged from 18 to 72 years (average: 36 years) and follow-up from 12 to 74 months (average: 26 months). A surgical algorithm of nine separate procedures involving at least two recti muscles on each eye was used for each patient. Most patients had associated systemic and/or ocular diagnoses, including albinism (35%), amblyopia (23%), optic nerve or retinal disorders (48%), refractive error (80%), AHP (44%), aperiodicity (27%), and strabismus (69%). There were no serious surgical complications, with a reoperation rate of 12%. There were significant group mean increases in BVCA, AHP, contrast sensitivity, strabismic deviation, and NAFX after surgery. Sixty percent of patients who were legally ineligible for driving prior to surgery became eligible after eye muscle surgery. Conclusions: Adult patients with INS showed sustained improvement in many afferent and efferent measures of visual function after eye muscle surgery. [ J Pediatr Ophthalmol Strabismus . 2021;58(2):93–104.]
- Published
- 2021
42. Author response: Increased burden of familial-associated early-onset cancer risk among minority Americans compared to non-Latino Whites
- Author
-
Joseph L. Wiemels, W. James Gauderman, Qianxi Feng, Eric Nickels, Charité Ricker, Thomas M. Mack, Andrew D. Leavitt, Adam J. de Smith, Amy C. Yee, Lucy A. Godley, and Ivo S. Muskens
- Subjects
business.industry ,Medicine ,business ,Cancer risk ,Demography ,Early onset - Published
- 2021
- Full Text
- View/download PDF
43. COVID-19: Too Sweet to Handle? A Case of New-Onset Diabetes Mellitus with Severe Diabetic Ketoacidosis Precipitated by Mild COVID-19 Pneumonia
- Author
-
S. Ricker, E. C. Bradley, and A. J. Astua
- Subjects
Past medical history ,medicine.medical_specialty ,Diabetic ketoacidosis ,business.industry ,Insulin ,medicine.medical_treatment ,medicine.disease ,Polyuria ,Diabetes mellitus ,Internal medicine ,Medicine ,Ketonuria ,Chills ,medicine.symptom ,business ,Polydipsia - Abstract
Introduction: As further studies elucidate the extent of organ systems affected by COVID-19, extra-pulmonary involvement is emerging as an important contributor to its morbidity and lethality. Beta-islet cells in the pancreas have been shown to be affected by COVID-19 via ACE2 and TMPRSS2 receptors. Accordingly, diabetes mellitus (DM) has not only been described as an independent risk factor for severe COVID-19, but there is also an association between new-onset DM (NODM) and diabetic ketoacidosis (DKA) with COVID-19. This case report discusses a patient with NODM presenting with DKA precipitated by COVID-19. Case Summary: A 45-year-old male with no past medical history who emigrated from India in March 2020 presented to the emergency department with five days of dyspnea, chills, fatigue, polyuria, and polydipsia. He was COVID-19 PCR-positive while his labs were remarkable for WBC 14, sodium 126, bicarbonate 2, glucose 350, anion gap 33, pH 6.95, pCO2 26, lactate 4.4, D-dimer 479, LDH 350, Ferritin 2381, Procalcitonin 1.13, HIV negative, and significant ketonuria. Chest x-ray revealed bilateral lower lobe patchy infiltrates consistent with COVID-19. He was started on an insulin drip, therapeutic Enoxaparin, and fluid resuscitation. He did not require supplemental oxygen and was not treated with steroids or antivirals. He was transitioned to subcutaneous insulin after one day. He was discharged after an uncomplicated five-day hospital stay. Discussion: There has been an increasing number of reports describing DKA precipitated by COVID-19 in patients with NODM, though our patient presentation is unique because he had a mild COVID-19 course that precipitated severe DKA. This case indicates a more direct role of COVID-19 damaging beta-cells in the pancreas as our patient remained on insulin and no other diabetic medications at discharge and after follow-up, indicating a complete reliance on exogenous insulin and failure of the pancreas to produce insulin seen with type-1 DM. The patient's HbA1c of 13.3 indicates a chronic state of DM, though COVID-19 certainly contributed to establishing NODM and DKA likely by wiping the remaining function of the Beta-cells in the pancreas. This uncommon case presentation demonstrates that even mild COVID-19 can induce DKA, so it is imperative that further research be conducted on its mechanism and prevention in the future.
- Published
- 2021
- Full Text
- View/download PDF
44. Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma
- Author
-
Sabina Signoretti, Laure Hirsch, Adam S. Feldman, Thomas Denize, Xin Gao, Jiao Li, Jihye Park, Gwo-Shu Mary Lee, Emma R. Garner, Chris Labaki, Daniel Y.C. Heng, Ananthan Sadagopan, Ziad Bakouny, Catherine J. Wu, David F. McDermott, Bradley Alexander McGregor, Vidyalakshmi Sethunath, Eliezer M. Van Allen, Filipe Lf Carvalho, Natalie I. Vokes, Steven L. Chang, Shaan Dudani, Shatha AbuHammad, Toni K. Choueiri, Stephen Tang, Chun-Loo Gan, Praful Ravi, Nebiyou Y. Metaferia, Michelle S. Hirsch, Emily Walton, David A. Braun, Rizwan Haq, Destiny West, Srinivas R. Viswanathan, Gabrielle Bouchard, Alma Imamovic, Cora A. Ricker, John A. Steinharter, and Jackson Nyman
- Subjects
Immunophenotyping ,Somatic cell ,business.industry ,Renal cell carcinoma ,medicine ,Cancer research ,Chromosomal translocation ,medicine.disease ,business ,Kidney cancer ,CD8 ,Clear cell ,Immune checkpoint - Abstract
Translocation renal cell carcinoma (tRCC) is an aggressive and poorly-characterized subtype of kidney cancer driven by MiT/TFE gene fusions. Here, we define the landmarks of tRCC through an integrative analysis of 152 tRCC patients identified across multiple genomic, clinical trial, and retrospective cohorts. Most tRCCs harbor few somatic alterations apart from MiT/TFE fusions and homozygous deletions at chromosome 9p21.3 (19.2% of cases). Transcriptionally, tRCCs display a heightened NRF2-driven antioxidant response that is associated with resistance to many targeted therapies. Consistently, we find that outcomes for tRCC patients treated with vascular endothelial growth factor receptor inhibitors (VEGFR-TKI) are worse than those treated with immune checkpoint inhibition (ICI). Multiparametric immunofluorescence confirmed the presence of CD8 + tumor-infiltrating T cells compatible with a clinical benefit from ICI and revealed an exhaustion immunophenotype distinct from clear cell RCC. Our findings comprehensively define the clinical and molecular features of tRCC and may inspire new therapeutic hypotheses.
- Published
- 2021
- Full Text
- View/download PDF
45. Patient-centered Outcomes in HFrEF Following a Worsening Heart Failure Event: A Survey Analysis
- Author
-
Dominik Lautsch, Thomas Nagle, Martine C. Maculaitis, John A. Spertus, Xi Tan, Mei Yang, Bryan Ricker, Robert Hilkert, Joanne E. Brady, Luther T. Clark, and Sandra B. Dunbar
- Subjects
Heart Failure ,medicine.medical_specialty ,Ejection fraction ,business.industry ,Patient-centered outcomes ,medicine.medical_treatment ,Stroke Volume ,medicine.disease ,Logistic regression ,Hospitalization ,Heart failure ,Internal medicine ,Patient-Centered Care ,Surveys and Questionnaires ,Insomnia ,Medicine ,Anxiety ,Humans ,medicine.symptom ,Diuretic ,Cardiology and Cardiovascular Medicine ,business ,Depression (differential diagnoses) - Abstract
Heart failure is a chronic disease punctuated by intermittent exacerbations that require hospitalization or intravenous diuretic therapy. The association of worsening heart failure events (WHFEs) with patient-centered outcomes in heart failure with reduced ejection fraction (HFrEF) remains unexplored.Patients with HFrEF completed an online survey assessing health status, medication adherence, treatment satisfaction, treatment burden, and medication costs and affordability. Patients with and without WHFEs were compared on all study variables, with adjustment for patient characteristics using linear or logistic regression. Overall, 512 patients (52.0% WHFEs) were included. Patients with WHFEs more commonly had depression (55.3% vs 24.0%), anxiety (46.2% vs 17.9%), and insomnia (77.8% vs 44.7%; P0.001 for all). Patients with WHFEs had lower adjusted mean Kansas City Cardiomyopathy Questionnaire values (52.9 vs 56.0) and Satisfaction with Medications Questionnaire values (70.5 vs 72.6) and higher Treatment Burden Questionnaire scores (51.1 vs 45.1; P0.001). Medication-related beliefs and long-term concerns were independently associated with nonadherence in patients with WHFE (adjusted odds ratios: 4.2 and 5.2, respectively; P0.01 for both). Patients with WHFE incurred 50.0% higher median monthly out-of-pocket HF prescription medication costs and less often perceived HF medications to be affordable.WHFE is associated with several adverse impacts on patients with HFrEF. Additional support is warranted to manage symptoms, comorbidities, and HF treatments to improve adherence and outcomes.
- Published
- 2021
46. Rare Manifestation of Aspergillus in a Pediatric Patient with Cystic Fibrosis
- Author
-
David Ricker, Michael D. Zimmerman, Allison Langs-Barlow, and Mark E. Boseley
- Subjects
Aspergillus ,medicine.medical_specialty ,biology ,business.industry ,bacterial infections and mycoses ,Malignancy ,medicine.disease ,biology.organism_classification ,Cystic fibrosis ,Dermatology ,respiratory tract diseases ,Pediatric patient ,Pediatrics, Perinatology and Child Health ,Parenchyma ,medicine ,In patient ,Presentation (obstetrics) ,skin and connective tissue diseases ,business ,Aspergilloma - Abstract
Introduction: Endobronchial aspergilloma is a rare clinical presentation of aspergillus infection involving a fungal growth within the large airways. It is distinct from pulmonary aspergillomas which can form within damaged parenchyma such as cavitary lesions. Endobronchial aspergilloma most commonly presents in patients with underlying malignancy or an immunocompromised state. We present the first reported case of endobronchial aspergilloma in an immunocompetent pediatric patient with known cystic fibrosis (CF). Case Report: Our patient is a 12 year old female with …
- Published
- 2021
- Full Text
- View/download PDF
47. Systemic Opioid Prescribing Patterns and Total Cost of Care in Patients Initiating Spinal Cord Stimulation Therapy: A Retrospective Analysis
- Author
-
John A Hatheway, Eduardo M. Fraifeld, and Christine N Ricker
- Subjects
Total cost ,Spinal cord stimulation ,Discontinuation ,Original Research Articles ,medicine ,Clinical endpoint ,Humans ,In patient ,Medical prescription ,Interventional Pain & Spine Medicine Section ,Practice Patterns, Physicians' ,Retrospective Studies ,Spinal Cord Stimulation ,business.industry ,Chronic pain ,General Medicine ,medicine.disease ,Opioids ,Analgesics, Opioid ,Anesthesiology and Pain Medicine ,Opioid ,Anesthesia ,Neurology (clinical) ,Chronic Pain ,business ,AcademicSubjects/MED00010 ,medicine.drug - Abstract
Background Few studies have evaluated patterns of systemic opioid use among patients initiating spinal cord stimulation therapy for chronic pain. This study evaluated systemic opioid discontinuation and/or dose reduction and total health care cost after the start of spinal cord stimulation therapy. Methods Using a commercial insurance claims database (2008–2017), we analyzed opioid utilization patterns in patients initiating spinal cord stimulation therapy over a 1-year baseline and 2-year follow-up. The primary end point was defined as either discontinuation (≥365-day gap between prescription fills or total days’ supply in follow-up ≤30 days) or ≥50% reduction in average daily morphine milligram equivalent dose. “Costs” were defined as total payer plus patient out-of-pocket payments. Results A total of 5,878 patients met the selection criteria. Of these, 152 (2.6%) showed no opioid prescription data at any point in the study period. Among patients with one or more prescriptions, 42.0% met the primary end point (22.0% discontinued, and 20.0% reduced their dose by 50% or more). Mean total adjusted costs were significantly reduced in years 1 and 2 of follow-up relative to baseline (excluding device insertion costs). The average time to breakeven when accounting for device trial and permanent insertion cost was 3.1 years among those who met the composite end point and 4.2 years among those who did not. Conclusions This analysis shows that among patients who continued spinal cord stimulation therapy for at least 2 years, a significant proportion were able to reduce and/or discontinue systemic opioid use, with costs after the start of therapy significantly reduced relative to baseline.
- Published
- 2021
48. Analysis of anomalous head posturing in patients with infantile nystagmus syndrome
- Author
-
David Bruckman, Richard W. Hertle, Isabel Ricker, Kelly Wiseman, Cecily Kelleher, Rachida Bouhenni, and Neil L. McNinch
- Subjects
Male ,medicine.medical_specialty ,genetic structures ,Head (linguistics) ,Lateral flexion ,Visual Acuity ,Nystagmus ,Ophthalmologic Surgical Procedures ,Nystagmus, Pathologic ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Medicine ,Humans ,In patient ,Anterior posterior ,Prospective Studies ,Strabismus ,business.industry ,Infantile nystagmus syndrome ,Ophthalmology ,Oculomotor Muscles ,Pediatrics, Perinatology and Child Health ,030221 ophthalmology & optometry ,medicine.symptom ,business ,Head ,Student's t-test - Abstract
To investigate anomalous head posturing in patients with INS.This was a prospective, cohort analysis of clinical and anomalous head posture (AHP) data in 34 patients with INS and an AHP. Particular outcome measures included measurement of AHP in three dimensions of pitch (anterior posterior flexion/extension), yaw (lateral rotation), and roll (lateral flexion) during best-corrected binocular acuity testing and during their subjective sense of straight. Patients were also queried as to their subjective sense of head posture in forced straight position and in their preferred AHP. The paired t test was used to determine significance in differences between measures.A total of 34 patients (19 males [56%]) 9-56 years of age (mean, 16.5 ± 6) were included. Associated systemic or ocular system deficits were present in 30 patients (88%). AHP during best-corrected visual acuity testing averaged 16.5° ± 8.20° (range, 10°-51°), which was significantly different from the mean voluntary "comfortable" position only in the pitch and roll directions (P 0.001). There was a significant noncongruous response during subjective response to head posturing with most sensing their head as "crooked" (76.5%) when manually straightened (P = 0.001).The clinical AHP of patients with INS exists in all three spatial dimensions of pitch, yaw, and roll. Although the visual system may be causally related to the onset, amount, and direction of a compensatory AHP in patients with INS, its persistence over time or after surgical intervention is likely due to a combination of visual system (eg, nystagmus, strabismus) and nonvisual system (egocentric and musculo-skeletal) factors.
- Published
- 2021
49. Plenary Talk 7 - Quantum-Based Photonic Sensors for Pressure, Vacuum, and Temperature Measurements: A Vison of the Future with NIST on a Chip
- Author
-
Nikolai N. Klimov, Jacob E. Ricker, Julia Scherschligt, Kevin O. Douglass, Daniel S. Barker, Stephen Eckel, J. A. Fedchak, Zeeshan Ahmed, and Jay H. Hendricks
- Subjects
Materials science ,business.industry ,Optoelectronics ,NIST ,Photonics ,business ,Chip ,Quantum ,Temperature measurement - Published
- 2021
- Full Text
- View/download PDF
50. Foodborne diseases and food safety in sub-Saharan Africa: Current situation of three representative countries and policy recommendations for the region
- Author
-
Zachary T. Neuhofer, Jacob Ricker-Gilbert, Yurani Arias-Granada, Paul Ebner, and Jonathan Bauchet
- Subjects
Economics and Econometrics ,food safety ,Sub saharan ,Geography ,Sub-Saharan Africa ,business.industry ,Development economics ,foodborne illness ,Current (fluid) ,Food safety ,business ,Agricultural and Biological Sciences (miscellaneous) ,Food Consumption/Nutrition/Food Safety - Abstract
This article examines the current state of food safety preparedness and response in three representative countries in sub-Saharan Africa (SSA): Kenya, Senegal and South Africa. We focus on foodborne diseases associated with the microbial contamination of animal-sourced foods. The results of our analysis indicate that governments in all three countries have official programmes to limit foodborne diseases and mitigate the effects of outbreaks. However, the population in these three countries continues to experience a high burden of foodborne diseases, and knowledge of the specific causes and mitigation of these diseases in SSA is lacking. Furthermore, there is a need for more and better food safety education programming, as we found no study that has collected a representative sample to estimate the level of public awareness of foodborne pathogens in any of the three countries studied. Evidence also suggests that institutional capacity around food safety in both the public and private sectors is insufficient due to limited financial investment and technical capacity. We end by providing suggestions for improving food safety preparedness and response in the region.
- Published
- 2021
- Full Text
- View/download PDF
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.