1. A review of intraoperative lung-protective mechanical ventilation strategy
- Author
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Trung kien Nguyen, Duc Hanh Mai, Anh Nguyet Le, Quang Huy Nguyen, Chi Tue Nguyen, and The Anh Vu
- Subjects
Mechanical ventilation ,Lung ,Biotrauma ,business.industry ,medicine.medical_treatment ,030208 emergency & critical care medicine ,respiratory system ,Lung injury ,Critical Care and Intensive Care Medicine ,Pathophysiology ,respiratory tract diseases ,03 medical and health sciences ,0302 clinical medicine ,Anesthesiology and Pain Medicine ,Increased risk ,medicine.anatomical_structure ,030202 anesthesiology ,Anesthesia ,medicine ,In patient ,business ,Tidal volume - Abstract
Purpose of review To provide pieces of evidence and an overview of the pathophysiology of ventilator-induced lung injury (VILI) on subjects with noninjured lungs, and the intraoperative mechanical ventilation strategies to prevent VILI. Recent findings Numerous evidence has indicated that intraoperative mechanical ventilation is associated with an increased risk of postoperative pulmonary complications (PPCs) in patients with noninjured lungs. This risk is blamed for volutrauma, barotrauma, atelectrauma, and biotrauma, which are the primary mechanisms of ventilator-induced lung injury (VILI) during mechanical ventilation. VILI was worsened by a nonprotective ventilator setting using a high tidal volume (>10–12 ml/kg), a low level of positive end-expiratory pressure (PEEP
- Published
- 2021
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