1. Prognostic value of left ventricular mechanical dyssynchrony indices in long-standing type II diabetes mellitus with normal perfusion and left ventricular systolic functions on SPECT-MPI
- Author
-
Dharmender Malik, Ashwani Sood, Ajay Bahl, Komalpreet Kaur, Bhagwant Rai Mittal, and Madan Parmar
- Subjects
Adult ,Male ,medicine.medical_specialty ,030204 cardiovascular system & hematology ,Phase bandwidth ,Logistic regression ,Disease-Free Survival ,030218 nuclear medicine & medical imaging ,Cohort Studies ,Ventricular Dysfunction, Left ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,Diabetes mellitus ,Internal medicine ,Phase.standard deviation ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Survival analysis ,Aged ,Aged, 80 and over ,business.industry ,Spect mpi ,Myocardial Perfusion Imaging ,Middle Aged ,Prognosis ,medicine.disease ,Diabetes Mellitus, Type 2 ,Cardiology ,Female ,Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography ,Cardiology and Cardiovascular Medicine ,Phase analysis ,business ,Perfusion - Abstract
To test whether phase analysis indices from SPECT-MPI for left ventricular mechanical dyssynchrony (LVMD) are predictors of major adverse cardiac events (MACEs) in long-standing diabetes mellitus (DM). A total of 136 DM patients with normal perfusion and left ventricular systolic functions were followed up for about two years and divided into two groups according to the presence and the absence of MACEs. Thirteen (9.5%) patients experienced MACEs during follow-up. Patients experiencing MACEs showed significantly higher phase standard deviation (PSD) and wider phase bandwidth (PBW) than those who did not. Moreover, both PSD and PBW showed significant correlations (r = 0.25 and 0.27; P
- Published
- 2018