9 results on '"Monica Ungureanu"'
Search Results
2. The Importance of Diet in Predicting the Remission of Urticaria—Determination of Allergen-Specific IgE
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Monica Ungureanu, Bogdan A. Stana, Radu Ciorap, Tudor Ovidiu Popa, Liliana Sachelarie, and Irina Croitoru
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0301 basic medicine ,Medicine (General) ,allergen-specific IgE ,Immunoglobulin E ,Article ,03 medical and health sciences ,food allergens ,urticaria ,R5-920 ,0302 clinical medicine ,children ,Animals ,Humans ,Medicine ,Statistical analysis ,Prospective Studies ,Food allergens ,Child ,Prospective cohort study ,Allergen specific IgE ,Statistical software ,biology ,business.industry ,General Medicine ,Allergens ,Predictive value ,Diet ,030104 developmental biology ,030228 respiratory system ,Immunology ,Disease remission ,biology.protein ,Cattle ,Female ,business ,Food Hypersensitivity - Abstract
Background and Objectives: Different types of food introduced gradually in the diet will expose children to different food allergens, increasing the chance of developing allergic diseases. The aim of our study was to determine if allergen-specific IgE values can influence, depending on the diet, the prediction of remission of urticaria in children. Materials and Methods: This prospective study was conducted in 132 patients diagnosed over two years with urticaria, admitted to “Sf. Maria” Clinical Pediatric Hospital Iaşi. Total IgE assay was performed by ELISA, and determination of specific serum IgE by the CLA System Quanti Scan method (Innogenetics, Heiden, Germany). Data were gathered and statistical analysis was performed using statistical software SPSS, using descriptive and inferential statistics. Results: The determination of specific IgE to food allergens was performed on a total of 132 cases. The values of specific IgE were positive for one or more food allergens in 84 patients (63.64%). The most common allergens involved were: cow’s milk in 33.3% cases, egg white in 22.6% cases, and hazelnuts in 11.9% cases. The specific IgE values for the different types of food included in our study had a predictive value for disease remission. Conclusions: The determination of specific IgE confirms the presence of a particular food allergen and may have predictive value for the future development of an allergic manifestation.
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- 2021
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3. INFECTIONS AND PREMATURITY, IMPORTANT RISK FACTORS FOR NEONATAL MORBIDITY AND MORTALITY
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Dana Elena Mindru, Elena Tarca, Laura Florescu, Vasile Valeriu Lupu, Iasi Pharmacy, Alina Murgu, Simona Gavrilescu, and Monica Ungureanu
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Pediatrics ,medicine.medical_specialty ,neonatal infections ,business.industry ,prematurity ,General Engineering ,morbidity ,Infectious and parasitic diseases ,RC109-216 ,infant mortality ,Neonatal morbidity ,General Earth and Planetary Sciences ,Medicine ,business ,General Environmental Science - Abstract
Infant mortality is a major problem in developing countries and, unfortunately, this is the case of our country as well, given that Romania ranks first in the European Union in this respect, with an infant mortality rate of 9 ‰, compared to an average of roughly 4 ‰. Worldwide, over 15 million babies are born prematurely each year and, out of these, more than a million die due to prematurity and infections, which are the main risk factors for neonatal mortality. The risk of infection is several times higher in preterm newborns than in full-term newborns – about 80% of neonatal infections occur in premature infants. A significant proportion of the survivors of prematurity will have important neurological sequelae because of neonatal infections as well as of intracerebral bleeding or hypoxia at birth. Continuing medical education in both the general population and the medical sector is crucial in preventing premature births and neonatal infections and, consequently, in decreasing infant morbidity and mortality rates in our country.
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- 2016
4. Acute liver failure related to hepatitis B (a four-case series)
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Marius Radu, Monica Ungureanu, Doina Iovănescu, Alina Frangulea, Cleo Roşculeț, Mihaela Tudor, Cătălin Apostolescu, Bogdan Pavel, Aida Răşcanu, Monica Ivan, and Andrei Rogoz
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Hepatitis ,medicine.medical_specialty ,Pathology ,business.industry ,Mortality rate ,Liver failure ,Hepatitis B ,medicine.disease ,Viral infection ,Gastroenterology ,Infectious Diseases ,Medical microbiology ,Internal medicine ,Poster Presentation ,medicine ,business - Published
- 2013
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5. Pneumococcal meningitis: analysis of the cases admitted in the last year in the intensive care unit of the National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest
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Bogdan Pavel, Cătălin Apostolescu, Monica Ivan, Doina Iovănescu, Monica Ungureanu, Alina Frangulea, Andrei Rogoz, Marius Radu, Ana-Maria Petrescu, Aida Răşcanu, Cleo Roşculeț, and Mihaela Tudor
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medicine.medical_specialty ,Pathology ,business.industry ,Alternative medicine ,medicine.disease ,Intensive care unit ,law.invention ,Infectious Diseases ,Medical microbiology ,law ,Family medicine ,Poster Presentation ,Tropical medicine ,medicine ,business ,Meningitis - Published
- 2013
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6. Wind power short-term forecasting system
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Camelia-Ioana Dica, Daniela Vasiliu, C. Dica, Gh. Comanescu, and Monica Ungureanu
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Consumption (economics) ,Flexibility (engineering) ,Offshore wind power ,Engineering ,Wind power ,Meteorology ,business.industry ,Environmental economics ,Grid ,business ,Wind speed ,Term (time) ,Renewable energy - Abstract
The Romanian National Energy strategy is requesting that renewables quota to reach 33% of consumption in 2010 and 38% in 2020. One of the most challenging issues facing wind energy today is its maximal and reliable integration in the power markets. Due to transport / distribution grid lack of flexibility and high level of concentration in Dobrogea region of large wind developments the access to the grid in Romania is proving difficult. This paper explores the role of short-term forecasting of wind power in Dobrogea for the successful integration of large wind farm capacity (over 2,000 MW) into a single injection point.
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- 2009
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7. Immune correlations in chronic child urticaria
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Monica Ungureanu, Cristina Gena Dascalu, Mihaela Moscalu, and Celina Stafie
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Multivariate analysis ,biology ,business.industry ,General Medicine ,Logistic regression ,medicine.disease ,Immunoglobulin E ,Airborne allergen ,Atopy ,Immune system ,immune system diseases ,Immunology ,biology.protein ,Medicine ,Risk factor ,Antibody ,business - Abstract
Introduction: The growing prevalence of urticaria in children over the last decade and the importance of determining the involved pathogenic mechanisms as well as of detecting the etiologic factors are some of the aspects that led to the choice of research topic. Materials and Methods: The early diagnosis and the establishment of the therapeutic and prophylactic conduct in the urticaria are a necessity. There have been evaluated through a retrospective questionnaire, anamnesis and biochemical evaluation a number of 246 children diagnosed with chronic IgE and non IgE mediated urticaria, and prick tested for a wide range of food allergens. The assessment of the intensity of the eruption was done by calculating the urticaria activity score (UAS), both at diagnosis and at subsequent evaluations to assess the response to the treatment. The immunological investigations which were carried out included the determination of the IgA, IgG, IgM, total IgE and specific IgE to food allergens and airborne allergens, as well as the determination of the IgG4-type antibodies to 20 food allergens by means of enzyme immunoassay. The ELISA method was used for dosing the total IgE, while the CLA System Quanti Scan method (Innogenetics, Heiden, Germany) was used for determining the serum-specific IgE for 20 of the most common food allergens and airborne allergens (Innogenetics, Heiden, Germany). Results: Positive statistical correlations have been made with IgE and non IgE mediated reactions, also with IgG4 antibodies. The result of the multivariate analysis shows that the existence of the atopy represents a risk factor which significantly influences the allergic sensitisation (HR = 3.186→95% CI: 2.57-5.96), followed in the order of importance by food diversification before the age of 6.months (HR = 2.157→95% CI: 1.86-5.35), natural feeding before 3.months of age (HR = 1.78→95% CI: 1003-4581) and artificial or mixed feeding (HR = 1.56→95% CI: 1056-3861). Conclusion: There have been reported different correlations between specific IgE and IgG4 with different food allergens and the period of time between the onset and the duration of chronic urticaria. The regression of specific IgE has a predictive value upon the remission of urticaria (AUC=0.557, p=0.447, 95%CI: AUC→0.398–0.717). The logistic regression for analysis of the predictives factors for the regresson of urticaria showed several factors involved:.Speciphic IgE values, compliance for the eliminating diet and treatment, allergic antecedents and the eventual polisensitivisation.
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- 2016
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8. Critical patient disease characteristics
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Ana-Maria Petrescu, Bogdana Manu, Aida Răşcanu, Andrei Rogoz, Monica Ungureanu, Marius Radu, Alina Frangulea, Cleo Roşculeț, Doina Iovănescu, Cornel Camburu, Monica Ivan, and Cătălin Apostolescu
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Mechanical ventilation ,Pediatrics ,medicine.medical_specialty ,Pathology ,business.industry ,medicine.medical_treatment ,Mean age ,Retrospective cohort study ,Disease ,medicine.disease ,Sepsis ,Infectious Diseases ,medicine ,Oral Presentation ,Disease characteristics ,business ,Severe sepsis - Abstract
Methods We performed a retrospective study exclusively on cases of sepsis and severe sepsis, in which we analyzed the records of the patients admitted in our ward last year. We included 131 patients, with a mean age of 64 years. Of all patients admitted to the ICU, 73 died and 74 required mechanical ventilation for a mean duration of over 6 days. These data suggest the seriousness and complexity of the disease. More than 45 patients were diagnosed with sepsis with MSOF (more than 3 organ dysfunctions).
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- 2013
9. Last resort antibiotherapy in sepsis with MDR bacteria, one possible solution in a critical patient (case report)
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Andrei Rogoz, Cătălin Apostolescu, Marius Radu, Doina Iovănescu, Monica Ungureanu, Aida Răşcanu, Bogdana Manu, Ana-Maria Petrescu, Cleo Roşculeț, Cornel Camburu, Monica Ivan, and Alina Frangulea
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medicine.medical_specialty ,biology ,business.industry ,Bioinformatics ,biology.organism_classification ,medicine.disease ,Sepsis ,Medical microbiology ,Infectious Diseases ,Parasitology ,Tropical medicine ,Poster Presentation ,medicine ,Intensive care medicine ,business ,Bacteria - Full Text
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