1. Principled Subpopulation Analysis of the BetterBirth Study and the Impact of WHO’s Safe Childbirth Checklist Intervention
- Author
-
Girmaw Abebe Tadesse, Victor Akinwande, Megan Marx Delaney, William Ogallo, Katherine Semrau, Skyler Speakman, and Claire-Helene Mershon
- Subjects
History ,medicine.medical_specialty ,education.field_of_study ,Polymers and Plastics ,business.industry ,Public health ,Population ,Declaration ,Articles ,Industrial and Manufacturing Engineering ,Checklist ,Family medicine ,Intervention (counseling) ,Statistical significance ,medicine ,Global health ,Childbirth ,Business and International Management ,education ,business - Abstract
Background: World Health Organization (WHO) developed the Safe Childbirth Checklist as an intervention to improve care and outcomes in maternal and newborn health. In the primary BetterBirth traditional trial analysis, the intervention did not significantly improve . However, a novel subgroup-based analysis could identify subpopulations that benefited from the intervention. Methods: In this work, we employ data-driven analysis methods to identify differentiated subgroups with unexpected characteristics compared to the average population. Specifically, we aim to identify: 1) vulnerable subgroups and 2) subpopulation in the intervention arm with significantly reduced outcome. The method utilizes the existing subset scanning literature that searches over a combination of features to identify the differentiated groups. Findings: We found that low birthweight (
- Published
- 2023