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Erythema nodosum (EN) is a delayed-type hypersensitivity reaction that most often presents as erythematous, tender nodules on the shins. Common triggers for EN include infection, drugs, pregnancy, malignancy, and inflammatory conditions, such as sarcoidosis or gastrointestinal diseases; however, many cases are idiopathic. We present clinical case of 12 y.o girl with EN associated with EBV.

There is a difference between MIS-C and KD. This is probably a postinfectious inflammatory response manifested with elevation of inflammatory markers and signs of myocardial damage. So, MIS-C could be an analogue of late phase COVID-19, which we are seeing in adult patients. This phase is also characterized by “cytokine storm” and can include severe myocardial disfunction, renal damage and laboratory changes consistent with MAS. Despite growing numbers of children with MIS-C, it still remains as rare condition and has good outcome in majority of cases. Children with MIS-C need special care of rheumatologist, infectious disease and intensive disease specialist collaboration.

Aims: To evaluate whether chronic lung disease (CLD) without concomitant brain lesions influences cognitive and motor development in early ears. Method: Congitive, receptive and expressive language, gross and fine motor skills were evaluated by Bayley III Scales of Infant and Toddler Development in 32 preterm infants with CLD (without IVH or PVL) and 36 preterm infants without CLD, IVH and PVL and 30 term healthy infants. Developmental asessment was conducted at 9 an 24 months of corrected age. All groups have similare birth weight, gestational age and demographic and social charactheristics. Results: From evaluated 90 children 54.4% (n=49) were male, and 6.6% (n=6) were SGA. In comparison with Term born infants premature infants show lower cognitive, expressive language and fine motor scores on both assessment. 9 and 24 months, 32,2% (n=29) children presented with different delays in one or more areas, from them 48,2 % (n=12) show delay in one sphere, in other cases there were delay in 2 and more areas. At 9 months of age children with CLD show the lower fine motor scores compared with preterm group without CLD. At 24 months of corrected age preterm born children with LCD show lower scores in fine motor, expressive language and cognitive skills compared with preterm born infants without LCD, but difference was not significant, that can be explained by a small sample. Conclusion: CLD have an influence on child development, especially on fine motor (visual motor) and cognitive skills. There is the need for careful developmental follow-up of infants with CLD to see if the problems have long lasting effects.

The aim of our study was to evaluate the clinical characteristics and differences between the allergic (AR) and non-allergic (NAR) rhinitis in children. The study involved 98 patients admitted ion ambulatory department of Iashvili central clinical hospital. The clinical picture, allergic evaluation including blood eosinophil counts, serum total IgE, specific IgE, and skin prick test were assessed and personal and family history were collected. The mean age of patients was 8,2+ 2,4 and there were no significant differences in age and sex between the AR and NAR group. The study shows that 63,2 % (n=63) of children had AR, whereas 36,8 % (n=35) had NAR. Nasal pruritus was more frequent in children with AR (61,9% (n=39) vs. 25,7% (n=9) P P