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1. Efficacy and safety of co-formulated elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide in HIV-positive patients: real-world data

Author

Fehmi Tabak, Esra Zerdali, Dilek Yildiz, Hayat Kumbasar Karaosmanoglu, Alper Gunduz, Ilyas Dokmetas, Meliha Meriç Koç, Sibel Bolukcu, Inci Yilmaz Nakir, Bilgul Mete, Ozlem Altuntaş, BOLUKÇU, SİBEL, and MERİÇ KOÇ, MELİHA

Subjects
Adult, Male, Human immunodeficiency virus (HIV), HIV Infections, Dermatology, Quinolones, medicine.disease_cause, Emtricitabine, Tenofovir alafenamide, Sexual and Gender Minorities, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Pharmacology (medical), 030212 general & internal medicine, Homosexuality, Male, Tenofovir, 0303 health sciences, Alanine, Elvitegravir/cobicistat/emtricitabine/tenofovir, 030306 microbiology, business.industry, Elvitegravir, Cobicistat, Public Health, Environmental and Occupational Health, Virology, Regimen, Infectious Diseases, business, Real world data, medicine.drug
Abstract

Objectives: Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) is a recommended and widely used regimen for HIV infection. In this study, we aimed to determine the efficacy and safety of E/C/F/TAF in people living with HIV (PLWH), who are either treatment-naïve or switched from any tenofovir disoproxil fumarate-containing regimen. For switched patients, we aimed to determine the impact of switching from tenofovir disoproxil fumarate (TDF) to TAF on lipid profile and kidney functions. Methods: ACTHIV-IST Study Group produced a database, and five dedicated HIV centres in Istanbul entered data of PLWH who switched from any TDF-containing regimen to E/C/F/TAF and treatment-naïve patients who were initiated with the E/C/F/TAF regimen between January 2017 and December 2019. Clinical findings, viral parameters, lipid studies, renal function tests, adverse events and adherence to the treatment were recorded in this prospective observational study. Results: The study included a total of 614 switched and treatment-naïve patients. Of 430 treatment-experienced patients, 89% (382) were men, and the mean age was 42 ± 12 years. Among them, 47% (181/382) self-identified as men who have sex with men (MSM). The median duration of HIV diagnosis was 54 ± 29 months. The median duration of E/C/F/TAF use was 20 ± 36 months and that of previous treatment was 23 ± 18 months. HIV-RNA was undetectable at baseline and month 12 in 84.1% (360/428) and 86.1% (328/381) of patients, respectively ( p > 0.05). Mean CD4 counts were 708 ± 287 cells/µL and 802 ± 305 cells/µL at baseline and month 12, respectively ( p < 0.001). Serum creatinine levels remained stable during the treatment period. Mean total cholesterol levels at baseline and month 12 were 172 and 211 mg/dL ( p < 0.01), LDL-cholesterol 104 and 138 mg/dL ( p < 0.01), HDL-cholesterol 39 and 49 mg/dL ( p < 0.01) and triglycerides 134 and 174 mg/dL ( p < 0.01), respectively. The treatment was generally well tolerated. Eight patients discontinued the therapy (drug interaction: 3; lost to follow-up: 1; pregnancy: 1; pulmonary tuberculosis: 1; side effect: 1; patient’s decision: 1). Of 184 treatment-naïve patients, 88% (162) were men, and the mean age was 36.5± 12 years. Among them, 50% (81/162) self-identified as MSM. The mean duration of HIV infection was 21.6 ± 17.1 months. The mean duration of E/C/F/TAF use was 16 ± 4 months. HIV-RNA was undetectable at baseline and month 12 in 1% and 89.1% of patients, respectively. Mean CD4 counts at baseline and month 12 were 469 ± 223 cells/µL and 740 ± 298 cells/µL, respectively. During the treatment period, creatinine levels remained stable. Total cholesterol, LDL-cholesterol, triglyceride and also HDL-cholesterol levels increased. Mean total cholesterol levels at baseline and month 12 were 167 and 211 mg/dL ( p < 0.01), LDL-cholesterol 108 and 143 mg/dL ( p < 0.01), HDL-cholesterol 41 and 47 mg/dL ( p < 0.01) and triglycerides 136 and 172 mg/dL, respectively ( p < 0.01). The treatment was generally well tolerated. Three patients discontinued the therapy (drug interaction: 1; non-responder: 1; patient’s decision: 1). Conclusion: Starting with or switching to E/C/F/TAF in PLWH effectively suppresses HIV infection, is associated with an increase in CD4 cell count and is well tolerated in a real-life setting. Renal functions remained stable during the treatment. E/C/F/TAF use was associated with an increase in LDL-cholesterol and triglyceride levels along with an increase in HDL-cholesterol levels.

Published
2021

2. Surgical Precautions and Algorithmic Decision-Making for Surgical Procedures During the COVID-19 Pandemic

Author

Alper Yenigun, Nurtac Dagistanli, Arif Koytak, Orhan Ozturan, Meliha Meric Koc, YENİGÜN, ALPER, ÖZTURAN, ORHAN, MERİÇ KOÇ, MELİHA, and KOYTAK, İBRAHİM ARİF

Subjects
Operating Rooms, medicine.medical_specialty, 2019-20 coronavirus outbreak, Letter, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MEDLINE, COVID-19, Surgical precautions, Surgical procedures, Pandemic, medicine, Humans, Surgery, Intensive care medicine, business, Pandemics
Published
2020

3. Managing adult patients with infectious diseases in emergency departments: international ID-IRI study

Author

Cernat Roxana Carmen, Sholpan Kulzhanova, Yasemin Cag, Mohamed Elhassan Abbas Dafalla, Ozay Akyildiz, Amani El-Kholy, Ainur Sadykova, Ahmed Ashraf Wegdan, Anna Liskova, Jordi Rello, Fatma A. Amer, Ilyas Dokmetas, Behrouz Naghili, Natalia Dirani, Svjetlana Grgić, Michael M. Petrov, Sevil Alkan Ceviker, Jameela Alsalman, Jehan El-Kholy, Hakan Hasman, Serkan Oncu, Abu Hena Mostafa Kamal, Kalyan Koganti, Yasemin Yildiz-Kirazaldi, Mateja Jankovic Makek, Hulya Caskurlu, Rusmir Baljic, Selda Aslan, Razi Even Dar, Sergio Ramirez-Estrada, Mateja Logar, Cansu Bulut-Avsar, Joanna Zajkowska, Rosa Fontana Del Vecchio, Handan Alay, Aidos K Konkayev, Marzena Wojewodzka-Zelezniakowicz, Sally Hargreaves, Hakan Erdem, Amjad Mahboob, Ferran Llopis, Dumitru Irina Mgdalena, Ergys Ramosaco, Dilek Bulut, Ameen S. S. Alwashmi, Nikolay Mladenov, Esam Abdalla, Nirav Pandya, Lorenza Lambertenghi, Mustafa Altindiş, Hema Prakash Kumari, Andrea Marino, Yvon Ruch, Filiz Kizilates, Dirar Abdallah, Emine Kubra Dindar-Demiray, Antonio Cascio, Meliha Meric-Koc, Asiye Bahar-Kacmaz, Rehab H. El-Sokkary, Meltem Taşbakan, Ridvan Karaali, Handan Ankarali, Helena Monzón-Camps, Ilad Alavi-Darazam, Ghaydaa A. Shehata, Merve Sefa-Sayar, Fatma Kesmez-Can, Ege Üniversitesi, MERİÇ KOÇ, MELİHA, Erdem H., Hargreaves S., Ankarali H., Caskurlu H., Ceviker S.A., Bahar-Kacmaz A., Meric-Koc M., Altindis M., Yildiz-Kirazaldi Y., Kizilates F., Alsalman J., Cag Y., Kamal A.H.M., Dokmetas I., Dindar-Demiray E.K., Shehata G.A., Hasman H., Sadykova A., Llopis F., Ramosaco E., Logar M., Alay H., Kesmez-Can F., Ruch Y., Bulut D., Makek M.J., Marino A., Mahboob A., El-Kholy A., Abdallah D., Sefa-Sayar M., Karaali R., Aslan S., Dar R.E., Abdalla E., Monzon-Camps H., Baljic R., Mgdalena D.I., Naghili B., Abbas Dafalla M.E., Alwashmi A.S.S., Carmen C.R., Ramirez-Estrada S., Wojewodzka-Zelezniakowicz M., Akyildiz O., Zajkowska J., El-Sokkary R., Pandya N., Amer F., Alavi-Darazam I., Grgic S., Wegdan A.A., El-Kholy J., Bulut-Avsar C., Kulzhanova S., Tasbakan M., Kumari H.P., Dirani N., Koganti K., Konkayev A.K., Petrov M.M., Cascio A., Liskova A., Del Vecchio R.F., Lambertenghi L., Mladenov N., Oncu S., and Rello J.

Subjects
0301 basic medicine, Point prevalence survey, medicine.medical_specialty, Urologic Neoplasms, Referral, international ID-IRI study-, JOURNAL OF CHEMOTHERAPY, 2021 [Erdem H., Hargreaves S., ANKARALI H., ÇAŞKURLU H., Ceviker S. A. , Bahar-Kacmaz A., Meric-Koc M., ALTINDİŞ M., Yildiz-Kirazaldi Y., Kizilates F., et al., -Managing adult patients with infectious diseases in emergency departments], medicine.drug_class, Organ Dysfunction Scores, 030106 microbiology, Antibiotics, Practice Patterns, emergency, antibiotic, elderly, infection, sepsis, treatment, Global Health, Communicable Diseases, Sepsis, Hospital, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Pharmacology (medical), Practice Patterns, Physicians', Developing Countries, Respiratory Tract Infections, Pharmacology, Emergency Service, Physicians', Adult patients, business.industry, Patient Acuity, Antimicrobial, medicine.disease, humanities, Drug Utilization, Anti-Bacterial Agents, Infectious Diseases, Oncology, 030220 oncology & carcinogenesis, Emergency medicine, Emergency, sepsi, business, Emergency Service, Hospital
Abstract

We aimed to explore factors for optimizing antimicrobial treatment in emergency departments. A single-day point prevalence survey was conducted on January 18, 2020, in 53 referral/tertiary hospitals in 22 countries. 1957 (17%) of 11557 patients presenting to EDs had infections. The mean qSOFA score was 0.37 +/- 0.74. Sepsis (qSOFA >= 2) was recorded in 218 (11.1%) patients. The mean qSOFA score was significantly higher in low-middle (1.48 +/- 0.963) compared to upper-middle (0.17 +/- 0.482) and high-income (0.36 +/- 0.714) countries ( P < 0.001). Eight (3.7%) patients with sepsis were treated as outpatients. The most common diagnoses were upper-respiratory (n = 877, 43.3%), lower-respiratory (n = 316, 16.1%), and lower-urinary (n = 201, 10.3%) infections. 1085 (55.4%) patients received antibiotics. The most-commonly used antibiotics were beta-lactam (BL) and BL inhibitors (n = 307, 15.7%), third-generation cephalosporins (n = 251, 12.8%), and quinolones (n = 204, 10.5%). Irrational antibiotic use and inappropriate hospitalization decisions seemed possible. Patients were more septic in countries with limited resources. Hence, a better organizational scheme is required.

Published
2021

4. Diagnosis, treatment and prevention of infective endocarditis: Turkish consensus report-2019*

Author

Arif Atahan Çağatay, Nesrin Turhan, Ahmet Rüçhan Akar, Tuncay Hazirolan, Serap Simsek-Yavuz, Seniha Başaran, Meliha Meric-Koc, Hakan Demir, Murat Sargın, Elif Tükenmez-Tigen, Neziha Yılmaz, Yasemin Cag, Ayşegül Yeşilkaya, Emel Yilmaz, Nirgül Kılıçaslan, Mutlu Şeyda Velioğlu-Öcalmaz, Ayfer Şensoy, Şirin Menekşe, Mehmet Emirhan Işık, Lokman Hızmalı, Yeşim Uygun-Kızmaz, Necla Ozer, Güle Çınar Aydın, Serpil Öztürk, Sinan Aydoğdu, Denef Deniz, Mehmet Ali Özatik, Özlem Kurt Azap, Nursen Topcuoglu, Fatma Yilmaz-Karadag, Yasemin Tezer-Tekçe, Sibel Doğan Kaya, Mehmet Yilmaz, and MERİÇ KOÇ, MELİHA

Subjects
lcsh:Internal medicine, lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, Consensus, Turkey, Turkish, Cardiology, MEDLINE, lcsh:Medicine, medicine, Humans, infective endocarditis, lcsh:RC31-1245, Intensive care medicine, Societies, Medical, consensus report, Endocarditis, business.industry, lcsh:R, medicine.disease, language.human_language, Diagnosis treatment, lcsh:RC666-701, Infective endocarditis, language, Cardiology and Cardiovascular Medicine, business
Abstract

Infective endocarditis (IE) is a rare but still important as an infectious disease due to high rate of morbidity and substantial mortality. Although IE is not a notifiable disease in Turkey, and an incidence study has not been performed, the incidence may be higher than that in the developed countries due to frequent predisposing cardiac conditions and higher rates of nosocomial bacteremia, which may lead to IE in risk groups. IE generally affects the elderly in developed countries but it is frequently encountered among young individuals in Turkey. In order to reduce mortality and morbidity, it is critical to diagnose IE, to determine the causative agent, and to start treatment rapidly. Most patients cannot be diagnosed at the first visit, about half can be diagnosed after 3 months, and the disease often goes unnoticed. In patients diagnosed with IE, the rate of the identification of a causative organism is significantly lower in Turkey than that in developed countries. Some important microbiological diagnostic tests are not performed in most centers and several antimicrobials that are recommended as the first option for the treatment particularly antistaphylococcal penicillins, are unavailable in Turkey. These problems necessitate reviewing the epidemiological, laboratory, and clinical characteristics of IE in our country, as well as the current information about its diagnosis, treatment, and prevention together with local data. The diagnosis and treatment processes of IE should be standardized at every stage so that the management can be conducted in a setting in which physicians of various specialties are involved and is consistent with the current recommendations. The Study Group for Infective Endocarditis and Other Cardiovascular Infections of the Turkish Society of Clinical Microbiology and Infectious Diseases called for the collaboration of the relevant specialist organizations to establish a consensus report on the diagnosis, treatment, and prevention of IE in the context of current information and local data in Turkey.

Published
2020

5. International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

Author

Víctor Daniel Rosenthal, Hail M. Al-Abdely, Amani Ali El-Kholy, Safa A Aziz AlKhawaja, Hakan Leblebicioglu, Yatin Mehta, Vineya Rai, Nguyen Viet Hung, Souha Sami Kanj, Mona Foda Salama, Estuardo Salgado-Yepez, Naheed Elahi, Rayo Morfin Otero, Anucha Apisarnthanarak, Braulio Matias De Carvalho, Bat Erdene Ider, Dale Fisher, Maria Carmen S.G. Buenaflor, Michael M. Petrov, Ana Marcela Quesada-Mora, Farid Zand, Vaidotas Gurskis, Tanja Anguseva, Aamer Ikram, Daisy Aguilar de Moros, Wieslawa Duszynska, Nepomuceno Mejia, Florin George Horhat, Vladislav Belskiy, Vesna Mioljevic, Gabriela Di Silvestre, Katarina Furova, Gloria Y. Ramos-Ortiz, May Osman Gamar Elanbya, Hindra Irawan Satari, Umesh Gupta, Tarek Dendane, Lul Raka, Humberto Guanche-Garcell, Bijie Hu, Denis Padgett, Kushlani Jayatilleke, Najla Ben Jaballah, Eleni Apostolopoulou, Walter Enrique Prudencio Leon, Alejandra Sepulveda-Chavez, Hector Miguel Telechea, Andrew Trotter, Carlos Alvarez-Moreno, Luis Kushner-Davalos, J.E. Desse, D.M. Maurizi, A.M. Montanini, G.J. Chaparro, J.P. Stagnaro, A. Romani, A.C. Bianchi, G. Álvarez, A. Palaoro, M. Bernan, R. Cabrera-Montesino, C. Domínguez, C.G. Rodríguez, C.G. Silva, E. Bogdanowicz, F.O. Riera, G. Benchetrit, I. Perez, J. Vimercati, L.S. Marcos, L. Ramasco, M. Caridi, M.C. Oyola, M.C. Rodríguez, M.L. Spadaro, M.S. Olivieri, P. Saul, P.D. Juarez, R.H. Pérez, P. Botta, D.Q. Quintana, A.M. Ríos, V. Chediack, W. Chilon, Ameena Isa Alsayegh, Fatema Hasan Yaseen, Lateefa Fardan Hani, Saleh Fakher Sowar, Tahira Anwar Magray, E.A. Medeiros, A. Alves De Oliveira, A. Romario-Mendes, C. Fernandes-Valente, C. Santos, D. Escudeiro, D. Azevedo-Ferreira Lima, D. Azevedo-Pereira, E.M. Onzi-Siliprandi, F. Serpa-Maia, F. Aguiar-Leitao, G. Assuncao-Ponte, J. Dos Anjos-Lima, J. Olszewski, K. Harten Pinto Coelho, L.F. Alves De Lima, M. Mendonca, M.L. Maciel-Canuto Amaral, M.T. Tenorio, S. Gerah, M. Andrade-Oliveira-Reis, M. Moreira, M. Ximenes-Rocha Batista, R.S. Campos-Uchoa, R. Rocha-Vasconcelos Carneiro, R. Amaral De Moraes, S.C. Do Nascimento, T. Moreira-Matos, T.M. Lima-De Barros Araujo, T. De Jesus Pinheiro-Bandeira, V.L. Machado-Silva, W.M. Santos Monteiro, E. Hristozova, E.D. Kostadinov, K. Angelova, V.A. Velinova, V.J. Dicheva, X. Guo, G. Ye, R. Li, L. Song, K. Liu, T. Liu, G. Song, C. Wang, X. Yang, H. Yu, Y. Yang, A. Martínez, A.R. Vargas-García, A. Lagares-Guzmán, A.P. González, C. Linares, C. Ávila-Acosta, D. Santofimio, D. Yepes-Gomez, D.A. Marin-Tobar, D.P. Mazo-Elorza, E.G. Chapeta-Parada, G. Camacho-Moreno, G.E. Roncancio-Vill, I.A. Valderrama-Marquez, J.E. Ruiz-Gallardo, J.O. Ospina-Martínez, J. Osorio, J.I. Marín-Uribe, J.C. López, S. Gualtero, J.R. Rojas, K. Gomez-Nieto, L.Y.M. Rincon, L. Meneses-Ovallos, L.M. Canas-Giraldo, L.D. Burgos-Florez, M. Amaral-Almeida Costa, M. Rodriguez, N. Barahona-Guzmán, O. Mancera-Paez, P.A. Rios-Arana, R. Ortega, S.L. Romero-Torres, S.M. Pulido-Leon, S. Valderrama, V.M. Moreno-Mejia, W. Raigoza-Martinez, W. Villamil-Gomez, Y.A. Pardo-Lopez, A. Argüello-Ruiz, A. Solano-Chinchilla, G.A. Muñoz-Gutierrez, I. Calvo-Hernández, L. Maroto-Vargas, M.A. Zuniga, M. Valverde-Hernandez, O. Chavarria-Ugalde, B. Herrera, C. Díaz, M.M. Bovera, C. Cevallos, C. Pelaez, E. Jara, V. Delgado, E.E. Coello-Gordon, F. Picoita, F.M. Guerrero-Toapant, F. Valencia, G. Santacruz, H. Gonzalez, L.N. Pazmino, M.F. Garcia, M. Arboleda, M. Lascano, N. Alquinga, V. Ramírez, Reham H.A. Yousef, Abd El Moniem Moustafa, A. Ahmed, A.M. Elansary, Ahmad Mahmoud Ali, Ahmed Hasanin, Antoine Abdel Messih, Arwa Ramadan, B.A. El Awady, D.M. Hassan, Doaa Abd El Aziz, Hala Hamza, Hala Mounir Agha, Islam Abdullorziz Ghazi, J. ElKholy, May Abdel Fattah, Mervat Elanany, M. Mansour, M.M.A. Haleim, R. Fouda, Rasha Hamed El-Sherif, S. Bekeit, V. Bayani, Y.S. Elkholy, Y.M. Abdelhamid, Zeinab Salah, D.M. Rivera, A. Chawla, A.N. Manked, A. Azim, A. Mubarak, A. Thakur, A.V. Dharan, A. Patil, A. Sasidharan, Anil Kumar Bilolikar, A. Anirban Karmakar, A.M. Mathew, Anuja Kulkarni, Anuradha Agarwal, Anuradha Sriram, A. Dwivedy, Arnab Dasgupta, A. Bhakta, Arul Rose Suganya, A. Poojary, Ashwin Kumar Mani, Asmita Sakle, Babu K. Abraham, Baby Padmini, B. Ramachandran, Banambar Ray, Basanta Kumar Pati, Bhaskar Narayan Chaudhury, Biraj Mohan Mishra, S. Biswas, M. Bri Saibala, Burhan Q. Jawadwala, C. Rodrigues, Chirag Modi, Chirag Patel, D.K. Khanna, Dedeepiya Devaprasad, Deepa Divekar, Deepesh G. Aggarwal, J.V. Divatia, Dolatsinh Zala, Edwin Pathrose, Fazil Abubakar, Felcy Chacko, G.S. Gehlot, Gautam Khanna, H.K. Sale, Indranil Roy, Jayant Shelgaonkar, Jehangir Sorabjee, Jincy Eappen, Justin Mathew, Jyotishka Pal, Karthikeya Varma, Kashmira Limaye Joshi, Kavita Sandhu, R. Kelkar, Lakshmi Ranganathan, L. Pushparaj, Madhav Lavate, Madhavi Latha, Madhupriya Suryawanshi, M. Bhattacharyya, Maithili Kavathekar, Manoj Kumar Agarwal, Mayur Patel, Mehul Shah, M.N. Sivakumar, Mohit Kharbanda, Mrinmoy Bej, Mrunalini Potdar, M. Chakravarthy, M. Karpagam, S.N. Myatra, N. Gita, N.P. Rao, N. Sen, N. Ramakrishnan, N. Jaggi, N. Saini, N.K. Pawar, Nikhil Modi, Nirav Pandya, Nisith Mohanty, Pooja Thakkar, Pradnya Joshi, Prafulla Kumar Sahoo, Pravin Kumar Nair, Priyadarshini Senthil Kumar, Priyanka Patil, Purnima Mukherjee, P. Mathur, Purvi Shah, R. Sukanya, Rajalakshmi Arjun, Rajesh Chawla, Ram Gopalakrishnan, Ramesh Venkataraman, S. Raut, Ravikumar Krupanandan, Reshma Tejam, Richa Misra, Ritesh Debroy, S. Saranya, Sajith Narayanan, Sanghamitra Mishra, Sanjith Saseedharan, Sankar Sengupta, S.K. Patnaik, Saswati Sinha, Seelas Blessymole, Seema Rohra, Senthilkumar Rajagopal, Shanta Mukherjee, Sharmila Sengupta, Sheeba John, Shefali Bhattacharya, null Sijo, Sinchan Bhattacharyya, S. Singh, T. Sohanlal, Sonali Vadi, S.S. Dalal, S.K. Todi, Subodh Kumar, Sudha Kansal, Sudhjan Misra, Sudipta Bhattacharyya, Suhas Nirkhiwale, Sujit Kar Purkayastha, Sujoy Mukherjee, S. Sahu, Sunil Sharma, Suresh Kumar, S. Basu, S. Shetty, S. Shah, T. Singhal, Thara Francis, Thejasvini Anand, V. Venkateshwar, Valsa Thomas, V. Kothari, null Velupandi, Vini Kantroo, Gortap Sitohang, Retno Kadarsih, Anahita Sanaei, Behzad Maghsudi, Golnar Sabetian, Mansoor Masjedi, Masoud Alebouyeh, Somayeh Jahani Sherafat, Yassir Khidir Mohamed, Abdulrahim Al Khamis, Adnan Soliman Alsaadi, Ahmed Abdoh Al-Jarie, Aisha Hassan Mutwalli, A.S.K. Rillorta, Anumol Thomas, Ashraf Kelany, Athena Manao, Dhaffer Moghram Alamri, E.B. Santiago, E.P. Cruzpero, Fahad Ahmed Sawan, Fatima Abdullah Al Qasmah, Haeel Alabdaly, Hajer Am Al-Dossary, Hala Ahmed, Hala Roshdi, Halima Yahia Al-Alkami, Hana Hanafi, Hassan Eisa Ammari, Hatem Mohd Al Hani, Ibrahim A.M. Alzaydani Asiri, Jeffrey Asidera Mendoza, Jomol Philipose, Joy Ola Selga, null Kehkashan, Khalid Mohammed Ghalilah, Leide Shyrine Redito, L. Josph, M. Al-Alawi, Manal Mansour Al-Gethamy, Marjory Madco, M.G. Manuel, M. Girvan, Mervat Aldalaton, M. De Guzman, Modhi Alkhamaly, Mohammad Masfar, Mohammed Ahmed Ali Karrar, Munayfa Musallam Al Azmi, Myrna Lim Quisai, Myrna Misador Torres, N. Al-Abdullah, Nader Ahmed Tawfic, Nashwa Elsayed, Nawal Salah Abdulkhalik, Nehad Abdulshakour Bugis, Neilia Cardinal Ariola, N. Gad, Nesreen Alghosn, Nidal Tashkandi, N. Al Zharani, P.A. De Vera, Radhika Krishnan, Raed Hassan Al Shehri, Rasha Nour Aldeen Jaha, Reny Thomas, Rhea Lynn Cresencia, R. Penuliar, R.V. Lozada, S. Al Qahtani, Sameh Twfik, Sarah Hassan Al Faraj, Sherin El-Sherbiny, Siti Jhulmina B. Alih, Solita Briones, Syed Zahid Bukhari, Tariq Saad Abdulhadi Alotaibi, Uma Gopal, Usha Nair, Wael Abdulrahman Abdulatif, Waleed Mohd Hussain, Wynndale Mae Demotica, G. Spahija, N. Baftiu, A. Gashi, Abeer A. Omar, A.M. Mohamed, F.M. Rebello, Haifaa Hassan Almousa, Naglaa Mahmoud Abdo, S.M. George, Soad Khamis, Suja Thomas, A. Ahmad Zaatari, A. Anwar Al Souheil, H. Ayash, I. Zeid, J. Tannous, N.K. Zahreddine, R. Ahmadieh, T. Mahfouz, T. Kardas, V. Tanzi, Z. Kanafani, Z. Hammoud, A. Dagys, D. Grinkeviciute, R. Kevalas, T. Kondratas, Milena Petrovska, Katja Popovska, Zan Mitrev, Zaneta Bogoevska Miteva, Katerina Jankovska, Snezana Tufekcievska Guroska, Chin Seng Gan, Ainul Auzani Othman, Aliza Mohamad Yusof, Anis Siham Zainal Abidin, Fadzlina Abdul Aziz, Foong Kit Weng, Hasimah Zainol, Kamal Bashar Abu Bakar, Lucy Chai See Lum, Marzida Mansor, Mazuin Kamarul Zaman, Mohamad Fadhil Hadi Jamaluddin, Mohd Shahnaz Hasan, Raha Abdul Rahman, Rhendra Hardy Mohamad Zaini, Rosliza Zhazali, Sasheela Sri La Sri Ponnampala, Soo Lin Chuah, Wan Fadzlina Wan Mohd Shukeri, Wan Nazaruddin Wan Hassan, Wan Nurbayah Wan Yusoff, Wan Rahiza Wan Mat, M.A. Cureno-Diaz, G. Aguirre-Avalos, A. Flores-Alvarado, A. Cerero-Gudino, A. Zamores-Pedroza, B. Cano-Munoz, B.E. Hernandez-Chena, C.C. Carreon-Martinez, H. Coronado-Magana, F. Corona-Jimenez, E. Rodriguez-Noriega, E. Alcala-Martinez, E. Gonzalez-Diaz, F.M. Guerra-Infante, G. Arteaga-Troncoso, G. Martinez-Falcon, G. Leon-Garnica, H.A. Delgado-Aguirre, H.R. Perez-Gomez, I.E. Sosa-Gonzalez, J.A. Galindo-Olmeda, J.J. Ayala-Gaytan, J. Rodriguez-Pacheco, L. Zamorano-Flores, J.A. Lopez-Pulgarin, M.G. Miranda-Novales, M. Ramírez, M. Lopez-Hurtado, M. Lozano, M.E. Gomez, M.E. Sanchez-Castuera, M. Kasten-Monges, M. Gonzalez-Martinez, M. Sanchez-Vargas, M.C. Culebro-Burguet, M.A. Altuzar-Figueroa, J.C. Mijangos-Mendez, O.G. Ramires, O.S. Espinosa, R. De Leon-Escobedo, R. Salas-Flores, R. Ruiz-Rendon, S. Petersen-Morfin, S.A. Aguirre-Diaz, S. Esparza-Ahumada, S. Vega-Gonzalez, V. Gaona-Flores, V.A. Monroy-Colin, Z. Cruz-Rivera, A. Bat-Erdene, Batsaikhan Narankhuu, Batsuren Choijamts, Battsetseg Tuvdennyam, Byambadorj Batkhuu, K.H. Chuluunchimeg, D. Enkhtsetseg, G. Batjargal, G. Bayasgalan, M. Dorj, Naranpurev Mendsaikhan, Otgon Baatar, P. Suvderdene, S. Baigalmaa, T. Khajidmaa, Tsolmon Begzjav, null Tsuyanga, Z. Ariyasuren, A.A. Zeggwagh, K. Berechid, K. Abidi, N. Madani, R. Abouqal, Anjeela Koirala, Rashmi Giri, Samana Sainju, Subhash Prasad Acharya, Abeera Ahmed, Aun Raza, Azra Parveen, Faisal Sultan, Maria Khan, Nadeem Paul, Nargis Daud, Sana Yusuf, Summiya Nizamuddin, E. Garcia-Mayorca, E.G. Castaño, J.L. Moreno-Castillo, J.M. Ballinas-Aquino, L. Lara, M. Vargas, M.I. Rojas-Bonilla, S.J. Ramos, T. Mapp, V. De Iturrado, C.E. La Hoz Vergara, C.F. Linares-Calderon, D. Moreno, E. Ramirez, F.M. Ramírez Wong, G.M. Montenegro-Orrego, H.R. Sandoval-Castillo, J. Pichilingue-Chagray, J. Mueras-Quevedo, K.F. Aibar-Yaranga, L.I. Castillo-Bravo, L.M. Santivanez-Monge, M.J. Mayorga-Espichan, M.L.G. Rosario-Tueros, M.V. Changano-Rodriguez, N.E. Salazar-Ramirez, V.A. Marquez-Mondalgo, Anna Lyn N. Tajanlangit, Arnefelina S. Tamayo, Cristina Mari Jean P. Llames, Ever Labro, Ana P. Dy, J.D. Fortin, L.D. Bergosa, L.G. Salvio, V. Bermudez, M.C. Sg-Buenaflor, M.F. Trajano, M.T. Mendoza, O.P. Javellana, R.R. Maglente, Y. Arreza-Galapia, J.A. Navoa-Ng, A. Kubler, B. Barteczko-Grajek, B. Dragan, M. Zurawska, M. Mikaszewska-Sokolewicz, M. Zielinska, G.Y. Ramos-Ortiz, A. Florin-Rogobete, C. Daliborca Vlad, D. Muntean, D. Sandesc, M. Papurica, M. Licker, Ovidiu Horea Bedreag, R. Popescu, S.D. Grecu, V. Dumitrascu, A. Molkov, D. Galishevskiy, M. Furman, A. Simic, D. Lekic, G. Ristic, J. Eremija, J. Kojovic, L. Nikolic, M. Bjelovic, A. Lesnakova, S. Hlinkova, M.O. Gamar-Elanbya, Namphon Supa, Pornpheth Prasan, Rungratchanee Pimathai, Suthinee Wanitanukool, Suwara Somabutr, N. Ben-Jaballah, A. Borgi, A. Bouziri, A. Dilek, A. Oncul, A. Kaya, Ali Pekcan Demiroz, A. Gunduz, A. Ozgultekin, Asuman Inan, A.N. Yalcin, A. Ramazanoglu, A. Engin, A. Willke, Basak Ceyda Meco, C. Aygun, C. Bulut, C. Uzun, C. Becerik, Cigdem Ataman Hatipoglu, Cigdem Yildirim Guclu, D. Ozdemir, D. Yildizdas, D. Ugurcan, E. Azak, E. Guclu, Esmeray Mutlu Yilmaz, F. Sebnem-Erdinc, F. Sirmatel, F. Ulger, Ferhat Sari, Filiz Kizilates, G. Usluer, G. Ceylan, G. Ersoz, G. Kaya, Gunay Tuncer Ertem, G. Senol, Hasan Agin, Hatice Cabadak, H. Yilmaz, Hulya Sungurtekin, Humeyra Zengin, H. Turgut, I. Ozgunes, I. Devrim, I. Erdem, Inşa Gul Ekiz Işcanlı, M. Mehmet Bakir, M.F. Geyik, M. Oral, M. Meric, M. Cengiz, M. Ozcelik, M. Altindis, M. Sunbul, N. Elaldi, N. Kuyucu, N. Unal, N. Oztoprak, N. Yasar, Nurettin Erben, Nuri Bayram, Oguz Dursun, Oguz Karabay, O. Coskun, Ozden Ozgur Horoz, Ozge Turhan, Ozlem Sarac Sandal, Recep Tekin, Saban Esen, Selvi Yener Erdogan, Serhat Unal, Sevim Karacorlu, Suha Sen, Suzan Sacar, Volkan Yarar, Yeliz Oruc, Yusuf Sahip, Zeynep Kaya, Anamma Philip, Ashraf Elhoufi, Hussain Alrahma, E. Sachez, F. Perez, G.D. Empaire, H. Vidal, L. Montes-Bravo, M.E. Guzman Siritt, N. Orozco, N. Navarrete, Y. Ruiz, Z. Duran-Gil De Anez, Dang Thi Van Trang, Dao Quang Minh, Dao Xuan Co, Dinh Pham Phuong Anh, Le Thi Anh Thu, Le Thi Diem Tuyet, Le Thi Thu Nguyet, Ngo uy Chau, Nguyen Gia Binh, Nguyen Phuc Tien, Nguyen Quoc Anh, Phan Thi Hang, Tran Thi My Hanh, Tran Thi Thuy Hang, Truong Anh Thu, Vo Thi Hong Thoa, Ondokuz Mayıs Üniversitesi, and MERİÇ KOÇ, MELİHA

Subjects
Male, 0301 basic medicine, Pediatrics, Imipenem, Antibiotic resistance, Epidemiology, health care facilities, manpower, and services, Ceftazidime, Global Health, 0302 clinical medicine, Bloodstream infection, Prospective Studies, 030212 general & internal medicine, Child, Aged, 80 and over, Cross Infection, Urinary tract infection, Incidence, Health Policy, Ventilator-associated pneumonia, Middle Aged, Intensive Care Units, Infectious Diseases, Amikacin, Child, Preschool, Limited resources countries, Female, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Health care-associated infection, 030106 microbiology, Catheter-associated urinary tract infection, Developing countries, Young Adult, 03 medical and health sciences, Intensive care, medicine, Humans, Hospital infection, Aged, business.industry, Infant, Newborn, Public Health, Environmental and Occupational Health, Infant, Device use, Nosocomial infection control, medicine.disease, Emergency medicine, Central line-associated bloodstream infections, business
Abstract

Hasan, M. Shahnaz/0000-0002-7493-7416; Abouqal, Redouane/0000-0002-6117-4341; Altindis, Mustafa/0000-0003-0411-9669; Masjedi, Mansoor/0000-0001-6175-9289; Popescu, Roxana/0000-0002-9387-1141; Mikaszewska-Sokolewicz, Malgorzata A/0000-0002-1148-7817; Meco, Basak Ceyda/0000-0003-2951-9634; Kumar, Perikala Vijayananda/0000-0001-8315-7000; Zand, Farid/0000-0003-3489-3372; Maghsoudi, Behzad/0000-0002-1279-8799; KAMARUL ZAMAN, MAZUIN/0000-0002-7920-6399; Gan, Chin Seng/0000-0002-6758-4798; Horoz, Ozden Ozgur/0000-0001-7590-650X; Medeiros, Eduardo A/0000-0002-6205-259X; Sabetian, Golnar/0000-0001-8764-2150; UNAL, SERHAT/0000-0003-1184-4711; Gan, Chin Seng/0000-0002-6758-4798; Delia, Muntean/0000-0001-9100-4530; Yalcin, Ata Nevzat/0000-0002-7243-7354; Leblebicioglu, Hakan/0000-0002-6033-8543; Horhat, Florin George/0000-0001-6133-0204; Yousef, Reham H. A./0000-0003-4004-3008; Delgado Aguirre, Hector Alberto/0000-0001-5448-7975; El Kholy, Amani/0000-0002-0645-7664; Rodriguez Ferrer, Marena Luz/0000-0002-8053-8454; Sanaei Dashti, Anahita/0000-0002-2827-3575; KARABAY, OGUZ/0000-0003-1514-1685; Barahona G., Nayide/0000-0003-3559-6900; Stagnaro, Juan Pablo/0000-0003-3836-9957; Alexandru Florin, Rogobete/0000-0003-1286-4431; KAYA, ZEYNEP/0000-0002-8468-2103; Dragan, Barbara/0000-0003-3108-4211; alvarez Moreno, carlos Arturo/0000-0001-5419-4494; Gonzalez Martinez, Marisela del Rocio/0000-0003-1474-736X; Jayatilleke, Kushlani/0000-0002-3931-6630; Unal, Necmettin/0000-0002-9440-7893; Duszynska, Wieslawa/0000-0002-5880-4904; Ngo, Quy Chau/0000-0002-6787-2757; Elmanakhly, Arwa/0000-0001-8557-0536; yildizdas, dincer/0000-0003-0739-5108; Kanj, Souha/0000-0001-6413-3396; Gupta, Umesh/0000-0001-7717-1404 WOS: 000392626300014 PubMed: 27742143 Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DAHAI), we collected prospective data from861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central lineassociated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheterassociated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically. (C) 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. VDR; Foundation to Fight against Nosocomial Infections The funding for design, development, maintenance, technical support, data validation, and report generation of the Surveillance Online System, and the activities carried out at International Nosocomial Infection Control Consortium headquarters, were provided by VDR and the Foundation to Fight against Nosocomial Infections.

Published
2016

6. Hand Hygiene Compliance in Some Intensive Care Units of Turkey: Results of Multicentre Asklepeion Study

Author

Gül Durmuş, Sercan Ulusoy, Meliha Meriç Koç, Bilgin Arda, Emel Azak, Oğuz Reşat Sipahi, Cigdem Ataman Hatipoglu, Ramazan Gözüküçük, Filiz Koc, Nilgiin Deniz Kucuker, Nurhayat Kepeli, Nilay Bilgili Korkmaz, Derya Caglayan, Behiye Ulusoy, Kenan Ugurlu, Hilal Sipahi, Sevil Alkan Çeviker, Habibe Tülin Elmaslar Mert, Firdevs Aksoy, Gunes Senol, Handan Alay, Aye Uyan Onal, Hüsnü Pullukçu, Demet Dikis, Emine Sehmen, Sukran Askit Barik, MERİÇ KOÇ, MELİHA, and Ege Üniversitesi

Subjects
Results of Multicentre Asklepeion Study-, MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.7, 2018 [Onal A. U. , AKSOY F., Azak E., Koc M., Ceviker S. A. , Hatipoglu C. A. , Gozukucuk R., Sehmen E., Ugurlu K., Senol G., et al., -Hand Hygiene Compliance in Some Intensive Care Units of Turkey], Microbiology (medical), hospital-acquired infections, General Immunology and Microbiology, business.industry, media_common.quotation_subject, lcsh:R, lcsh:Medicine, nosocomial, infection control and prevention, medicine.disease, lcsh:Infectious and parasitic diseases, Compliance (psychology), Infectious Diseases, healthcare-associated infections, Hygiene, Intensive care, medicine, epidemiology, lcsh:RC109-216, Medical emergency, business, media_common
Abstract

WOS: 000463053800027, Introduction: Hand hygiene is one of the most cost-effective infection control measures. In this multicenter Study we analysed the hand hygiene compliance observation results of 15 hospitals in Turkey. Materials and Methods: This study was performed in intensive care units (ICUs) of 15 hospitals (Eight terriary-care educational hospitals, six state hospitals and one private hospital) from 11 cities from six regions of Turkey The observations were made by infection control practitioners according to the World Health Organization - Five Moments for Hand Hygiene (WHO-5) indications rule for hand hygiene and overall compliance rates were calculated. Observations were unblinded (healthcare professionals knew that they were observed). The study period included 2015 and 2016 calendar years. Results: There was a statistically significant increase in hand hygiene compliance rates in 2016 versus 2015. The overall number of hand hygiene indications and compliance in 2015 and 2016 were 60071/78116-76,9% and 66551/83607-79,6% (p=0.0001), respectively. Nurses were the most compliant group in both years. The highest compliance was in after body fluid exposure indication (88.2%-2015 and 91.4%-2016) while the lowest compliance was in before patient contact indication (61.3%-2015 and 65%-2016). Conclusion: The presented data suggest that under unblinded observations, hand hygiene compliance seems to be in relatively acceptable rates in Turkey. Centers with compliance rates below 50 percentile rates in any of the 5 moments should increase efforts to enhance compliance in that indication.

Published
2019

7. Portraying infective endocarditis

Author

Ilker Inanc Balkan, Najada Como, André Silva-Pinto, Antonio Cascio, Canan Agalar, Meliha Meric-Koc, Tatjana Lejko Zupanc, Oday Abu Ajamieh, Simin Aysel Florescu, Selma Tosun, Meltem Taşbakan, Asuman Inan, Rosa Fontana Del Vecchio, Edmond Puca, Güven Çelebi, Ayse Sagmak-Tartar, Abdullah Umut Pekok, Yasemin Cag, Gülden Ersöz, Sumeyra Karakus, Safak Ozer-Balin, Jamal Wadi, Sukran Kose, Yves Hansmann, Hacer Deniz Ozkaya, Nefise Oztoprak, Hakan Erdem, Serkan Oncu, Jesper Damsgaard Gunst, Yvon Ruch, Aysegul Erdem, Gilda Tonziello, Ayse Batirel, Rahmet Guner, Irina Magdalena Dumitru, Lurdes Santos, Raquel Duro, Nesrin Ghanem-Zoubi, Arjeta Dedej, Serda Gulsun, Mustafa Dogan, Necla Tulek, Alper Şener, Pedro Palma Martins, Ilkay Bozkurt, Deborah Konopnicki, Fatma Sirmatel, Xavier Argemi, Meltem Avci, Fahad Almajid, Recep Tekin, Nicola Petrosillo, Corneliu Petru Popescu, Ayse Kaya-Kalem, Imran Hasanoglu, Atilla Iyisoy, Jean Philippe Mazzucotelli, Ejaz Ahmed Khan, Sema Sarı, Derya Ozturk-Engin, Nicolas Dauby, Erdem H., Puca E., Ruch Y., Santos L., Ghanem-Zoubi N., Argemi X., Hansmann Y., Guner R., Tonziello G., Mazzucotelli J.-P., Como N., Kose S., Batirel A., Inan A., Tulek N., Pekok A.U., Khan E.A., Iyisoy A., Meric-Koc M., Kaya-Kalem A., Martins P.P., Hasanoglu I., Silva-Pinto A., Oztoprak N., Duro R., Almajid F., Dogan M., Dauby N., Gunst J.D., Tekin R., Konopnicki D., Petrosillo N., Bozkurt I., Wadi J., Popescu C., Balkan I.I., Ozer-Balin S., Zupanc T.L., Cascio A., Dumitru I.M., Erdem A., Ersoz G., Tasbakan M., Ajamieh O.A., Sirmatel F., Florescu S., Gulsun S., Ozkaya H.D., Sari S., Tosun S., Avci M., Cag Y., Celebi G., Sagmak-Tartar A., Karakus S., Sener A., Dedej A., Oncu S., Del Vecchio R.F., Ozturk-Engin D., Agalar C., Virulence Bactérienne Précoce : fonctions cellulaires et contrôle de l'infection aigüe et subaigüe, Université de Strasbourg (UNISTRA), Virulence bactérienne précoce : fonctions cellulaires et contrôle de l'infection aiguë et subaiguë, Nanomédecine Régénérative (NanoRegMed), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), MERİÇ KOÇ, MELİHA, İÜC, Cerrahpaşa Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Uşak Üniversitesi, Zonguldak Bülent Ecevit Üniversitesi, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Sırmatel, Fatma, and OMÜ

Subjects
Male, Internationality, Aucun, Infective endocarditi, medicine.disease_cause, Medical microbiology, 80 and over, Blood culture, Hospital Mortality, Aged, 80 and over, medicine.diagnostic_test, biology, Endocarditis, Bacterial, General Medicine, Sciences bio-médicales et agricoles, Middle Aged, Staphylococcal Infections, Sciences du Vivant [q-bio]/Microbiologie et Parasitologie, Viridans Streptococci, Catheter, Infectious Diseases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Staphylococcus aureus, Infective endocarditis, Aortic Valve, Mitral Valve, Female, Microbiology (medical), Adult, medicine.medical_specialty, Prosthesis-Related Infections, Adolescent, aureus, Young Adult, Internal medicine, medicine, Humans, results of multinational ID-IRI study-, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, cilt.38, ss.1753-1763, 2019 [Erdem H., Puca E., Ruch Y., Santos L., Ghanem-Zoubi N., Argemi X., Hansmann Y., Guner R., Tonziello G., Mazzucotelli J., et al., -Portraying infective endocarditis], Prosthetic, Aged, Native Valve Endocarditis, Bacteria, business.industry, Endocarditis, Bacterial, medicine.disease, biology.organism_classification, S. aureus, Viridans streptococci, business, Native
Abstract

Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients had pacemaker lead endocarditis, and 1 patient had catheter port endocarditis. Eighteen percent of NVE patients were hospital-acquired. PVE patients were classified as early-onset in 24.9%. A total of 385 (44.4%) patients had major embolic events, most frequently to the brain (n = 227, 26.3%). Blood cultures yielded pathogens in 766 (88.4%). In 101 (11.6%) patients, blood cultures were negative. Molecular testing of vegetations disclosed pathogens in 65 cases. Overall, 795 (91.7%) endocarditis patients had any identified pathogen. Leading pathogens (Staphylococcus aureus (n = 267, 33.6%), Streptococcus viridans (n = 149, 18.7%), enterococci (n = 128, 16.1%), coagulase-negative staphylococci (n = 92, 11.6%)) displayed substantial resistance profiles. A total of 132 (15.2%) patients had cardiac abscesses; 693 (79.9%) patients had left-sided endocarditis. Aortic (n = 394, 45.4%) and mitral valves (n = 369, 42.5%) were most frequently involved. Mortality was more common in PVE than NVE (NVE (n = 101, 16%), PVE (n = 49, 22.9%), p = 0.042)., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2019

8. Comparison of brucellar and tuberculous spondylodiscitis patients: results of the multicenter 'Backbone-1 Study'

Author

Tumer Guven, Hakan Erdem, Rehab H. El-Sokkary, Dilara Inan, Serda Gulsun, Fatma Yilmaz-Karadag, Gunay Tuncer-Ertem, Elif Sahin Horasan, Şafak Kaya, Ali İrfan Baran, Recep Tekin, Archontoula Fragou, Seniha Senbayrak, Esra Arslanalp, Fatma Sirmatel, Selçuk Kaya, Ayşe Willke, Salih Cesur, Sani H. Aliyu, Ergys Ramosaco, Meliha Meric-Koc, Meltem Taşbakan, Sukran Kose, Gönül Aslan, Efthymia Giannitsioti, Gonul Sengoz, Haluk Vahaboglu, Nazif Elaldi, Selma Ates-Guler, Birgul Mete, Sesin Kocagöz, Hulya Kusoglu, Ertugrul Guclu, Dilek Yildiz Sevgi, Hava Yilmaz, Gulfem Akengin Ocal, Ayse Batirel, Behiye Dede, Birsen Cetin, Tunc Oktenoglu, D. Ashraf ALGallad, Mehmet Ulug, Sebnem Senol, Banu Karaca, Ilker Inanc Balkan, Aygul Dogan-Celik, Nural Bekiroglu, Gonul Cicek-Senturk, Filiz Pehlivanoglu, Asuman Inan, MERİÇ KOÇ, MELİHA, Erdem, H, Elaldi, N, Batirel, A, Aliyu, S, Sengoz, G, Pehlivanoglu, F, Ramosaco, E, Gulsun, S, Tekin, R, Mete, B, Balkan, II, Sevgi, DY, Giannitsioti, E, Fragou, A, Kaya, S, Cetin, B, Oktenoglu, T, DoganCelik, A, Karaca, B, Horasan, ES, Ulug, M, Man, A, Arslanalp, E, Ates-Guler, S, Willke, A, Senol, S, Inan, D, Guclu, E, Tuncer-Ertem, G, Meric-Koc, M, Tasbakan, M, Senbayrak, S, Cicek-Senturk, G, Sirmatel, F, Ocal, G, Kocagoz, S, Kusoglu, H, Guven, T, Baran, AI, Dede, B, Yilmaz-Karadag, F, Kose, S, Yilmaz, H, Asian, G, Algallad, DA, Cesur, S, El-Sokkary, R, Bekiroglu, N, Vahaboglu, H, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Güçlü, Ertuğrul, [Erdem, Hakan] Culhane Med Acad, Dept Infect Dis & Clin Microbiol, Ankara, Turkey -- [Elaldi, Nazif] Cumhuriyet Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Sivas, Turkey -- [Batirel, Ayse -- Ocal, Gulfem] Dr Lao Kirdar Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Aliyu, Sani] Cambridge Univ Hosp Fdn Trust, Addenbrookes Hosp, Clin Microbiol & Publ Hlth Lab, Cambridge, England -- [Sengoz, Gonul -- Pehlivanoglu, Filiz] Haseki Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Ramosaco, Ergys] Univ Hosp Ctr Mother Teresa, Infect Dis Hosp, Tirana, Albania -- [Gulsun, Serda -- Kaya, Safak] Diyarbakir Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Diyarbakir, Turkey -- [Tekin, Recep] Dicle Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Diyarbakir, Turkey -- [Mete, Birgul -- Balkan, Ilker Inanc] Istanbul Univ, Cerrahpasa Sch Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Sevgi, Dilek Yildiz] Sisli Etfal Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Giannitsioti, Efthymia -- Fragou, Archontoula] Attikon Univ Gen Hosp, Athens Univ Med Sch, Dept Internal Med, Athens, Greece -- [Kaya, Selcuk] Karadeniz Tech Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Trabzon, Turkey -- [Cetin, Birsen] Koc Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Oktenoglu, Tune] Koc Univ, Sch Med, Dept Neurosurg, Istanbul, Turkey -- [DoganCelik, Aygul] Trakya Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Edirne, Turkey -- [Karaca, Banu] Izmir Bozyaka Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Izmir, Turkey -- [Horasan, Elif Sahin] Mersin Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Mersin, Turkey -- [Ulug, Mehmet] Private Umit Hosp, Dept Infect Dis & Clin Microbiol, Eskisehir, Turkey -- [Man, Asuman -- Senbayrak, Seniha] Haydarpasa Numune Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Arslanalp, Esra -- Willke, Ayse -- Meric-Koc, Meliha] Kocaeli Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Kocaeli, Turkey -- [Ates-Guler, Selma] Kahramanmaras Sutcu Imam Univ, Sch Med, Dept Infect Dis & Clin Microbiol, TR-46050 Kahramanmaras, Turkey -- [Senol, Sebnem] Celal Bayar Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Manisa, Turkey -- [Inan, Dilara] Akdeniz Univ, Sch Med, Dept Infect Dis & Clin Microbiol, TR-07058 Antalya, Turkey -- [Guclu, Ertugrul] Sakarya Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Sakarya, Turkey -- [Tuncer-Ertem, Gunay -- Cesur, Salih] Ankara Numune Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Ankara, Turkey -- [Tasbakan, Meitem] Ege Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Izmir, Turkey -- [Cicek-Senturk, Gonul -- Asian, Gonul] Diskapi Yildirim Beyazit Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Ankara, Turkey -- [Sirmatel, Fatma] Abant Izzet Baysal Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Bolu, Turkey -- [Kocagoz, Sesin -- Kusoglu, Hulya] Acibadem Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Guven, Turner] Ankara Ataturk Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Ankara, Turkey -- [Baran, Ali Irfan] Yuzuncu Yil Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Van, Turkey -- [Dede, Behiye] Umraniye Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Yilmaz-Karadag, Fatma -- Vahaboglu, Haluk] Medeniyet Univ, Goztepe Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Kose, Sukran] Tepecik Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Izmir, Turkey -- [Yilmaz, Hava] Ondokuz Mayis Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Samsun, Turkey -- [Algallad, D. Ashraf -- El-Sokkary, Rehab] Zagazig Univ Hosp, Infect Control Unit, Az Zagazig, Egypt -- [Bekiroglu, Nural] Marmara Univ, Sch Med, Dept Biostat, Istanbul, Turkey, VAHABOGLU, Haluk -- 0000-0001-8217-1767, and Ondokuz Mayıs Üniversitesi

Subjects
Adult, Male, Spondylodiscitis, endocrine system, medicine.medical_specialty, Discitis, Constitutional symptoms, Context (language use), Brucellosis, Sequelae, Internal medicine, medicine, Back pain, Humans, Tuberculosis, Orthopedics and Sports Medicine, Abscess, Outcome, Aged, medicine.diagnostic_test, business.industry, Middle Aged, medicine.disease, Surgery, Orthopedics, Erythrocyte sedimentation rate, Female, Neurology (clinical), medicine.symptom, Complication, business
Abstract

WOS: 000366655100045, PubMed ID: 26386176, BACKGROUND CONTEXT: No direct comparison between brucellar spondylodiscitis (BSD) and tuberculous spondylodiscitis (TSD) exists in the literature. PURPOSE: This study aimed to compare directly the clinical features, laboratory and radiological aspects, treatment, and outcome data of patients diagnosed as BSD and TSD. STUDY DESIGN: A retrospective, multinational, and multicenter study was used. PATIENT SAMPLE: A total of 641 (TSD, 314 and BSD, 327) spondylodiscitis patients from 35 different centers in four countries (Turkey, Egypt, Albania, and Greece) were included. OUTCOME MEASURES: The pre- and peri- or post-treatment spinal deformity and neurologic deficit parameters, and mortality were carried out. METHODS: Brucellar spondylodiscitis and TSD groups were compared for demographics, clinical, laboratory, radiological, surgical interventions, treatment, and outcome data. The Student t test and Mann-Whitney U test were used for group comparisons. Significance was analyzed as two sided and inferred at 0.05 levels. RESULTS: The median baseline laboratory parameters including white blood cell count, C-reactive protein, and erythrocyte sedimentation rate were higher in TSD than BSD (p

Published
2015

9. Are Soap, Paper Towel and Alcohol-based Disinfectants Easily Accessible in Intensive Care Units in Turkey?: Results of the Phokai Study

Author

Türkkan Öztürk Kaygusuz, Oğuz Sipahi, Mustafa Dogan, Erdem Güven, Feride Kocak, S Alkan Ceviker, Derya Caglayan, Firdevs Aksoy, Yeşim Kürekçi, Metin Arslan, G Evik, Güven Çelebi, S Cagan Aktas, N Dogan, Ramazan Gözüküçük, Fatih Koc, Kenan Ugurlu, Burak Özdemir, Selçuk Özger, ME Isik, Ayşe Uyan, Sema Sarı, Fethiye Akgül, Rezan Harman, Handan Alay, B Isik, Hilal Sipahi, S Ozkoren Calik, Ilknur Esen Yildiz, Gunes Senol, Kevser Ozdemir, Gül Durmuş, Meliha Meriç Koç, HT Elmaslar Mert, Bilgin Arda, Nefise Oztoprak, Hamza Erdogan, Nurbanu Sezak, Aslıhan Demirel, A Ozgultekin, Tansu Yamazhan, Mehmet Uçar, Sercan Ulusoy, EK Dindar Demiray, G Unsal, Ahsen Oncul, [Uyan, Ayse -- Yamazhan, Tansu -- Arda, Bilgin -- Ulusoy, Sercan -- Sipahi, Oguz Resat] Ege Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Izmir, Turkey -- [Durmus, Gul] Bursa Yuksek Ihtisas Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Bursa, Turkey -- [Sezak, Nurbanu] Izmir Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Izmir, Turkey -- [Ozdemir, Burcu] Ankara Numune Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Ankara, Turkey -- [Kaygusuz, Turkkan] Elazig Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Elazij, Turkey -- [Oztoprak, Nefise] Antalya Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Antalya, Turkey -- [Ozdemir, Keyser] Pamukkale Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Denizli, Turkey -- [Aksoy, Firdevs] Karadeniz Tech Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Trabzon, Turkey -- [Ozgultekin, Asu] Haydarpasa Numune Training & Res Hosp, Clin Anesthesiol & Intens Care, Istanbul, Turkey -- [Koc, Meliha Meric] Kocaeli Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Kocaeli, Turkey -- [Oncul, Ahsen] Sisli Etfal Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Cagan Aktas, Sabahat] Dr Lutfi Kirdar Kartal Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Isik, Burcu] Istanbul Medeniyet Univ, Goztepe Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Celebi, Giiven] Bulent Ecevit Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Zonguldak, Turkey -- [Evik, Guliiz] Mersin Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Mersin, Turkey -- [Ozger, Selcuk] Dr Ersin Arslan Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Gaziantep, Turkey -- [Harman, Rezan] Private Sani Konukoglu Hosp, Clin Infect Dis & Clin Microbiol, Gaziantep, Turkey -- [Dindar Demiray, Emine Kubra] Celal Bayar Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Manisa, Turkey -- [Ozkoren Calik, Sebnem] Izmir Bozyaka Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Izmir, Turkey -- [Alkan Ceviker, Sevil] Balikesir State Hosp, Clin Infect Dis & Clin Microbiol, Balikesir, Turkey -- [Yildiz, Ilknur Esen] Recep Tayyip Erdogan Univ, Fac Med, Dept Infect Dis & Clin Microbiol, Rize, Turkey -- [Isik, Mehmet Emirhan] Kartal Kosuyolu Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Senol, Gunes] Dr Suat Seren Chest Dis & Chest Surg Training & R, Clin Infect Dis & Clin Microbiol, Izmir, Turkey -- [Sari, Sema] Turkiye Yuksek Ihtisas Hosp, Clin Intens Care, Ankara, Turkey -- [Dogan, Mustafa] Corlu State Hosp, Clin Infect Dis & Clin Microbiol, Tekirdag, Turkey -- [Ugurlu, Kenan] 25 Aralik & State Hosp, Clin Infect Dis & Clin Microbiol, Gaziantep, Turkey -- [Arslan, Mustafa] Amasya Univ, Sabuncuoglu Serefeddin Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Amasya, Turkey -- [Akgul, Fethiye] Batman State Hosp, Clin Infect Dis & Clin Microbiol, Batman, Turkey -- [Koc, Filiz] Kecioren Training & Res Hosp, Clin Infect Dis & Clin Microbiol, Ankara, Turkey -- [Kurekci, Yeim] Arnavutkoy State Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Caglayan, Derya] Torbali State Hosp, Clin Infect Dis & Clin Microbiol, Izmir, Turkey -- [Ucar, Mehmet] Usak Med Pk Hosp, Clin Infect Dis & Clin Microbiol, Usak, Turkey -- [Gozukucuk, Ramazan] Private Hisar Intercontinental Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Elmaslar Mert, Habibe Tulin] Ardahan State Hosp, Clin Infect Dis & Clin Microbiol, Ardahan, Turkey -- [Alay, Handan] Nenehatun Obstet & Gynecol Hosp, Clin Infect Dis & Clin Microbiol, Erzurum, Turkey -- [Erdogan, Haluk] Baskent Univ, Alanya Med & Res Ctr, Dept Infect Dis & Clin Microbiol, Antalya, Turkey -- [Demirel, Aslihan] Istanbul Bilim Univ, Fac Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Dogan, Nilgun] TOBB Univ Econ & Technol Hosp, Hosp Infect Control Comm, Ankara, Turkey -- [Kocak, Funda] Basaksehir State Hosp, Clin Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Guven, Emre] Beytepe Murat Erdi Eker State Hosp, Clin Infect Dis & Clin Microbiol, Ankara, Turkey -- [Unsal, Guieser] Bozok Univ, Hosp Infect Control Comm, Fac Med, Yozgat, Turkey -- [Sipahi, Hilal] Bornova Publ Hlth Ctr, Izmir, Turkey, MERİÇ KOÇ, MELİHA, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Yıldız, İlknur Esen, Zonguldak Bülent Ecevit Üniversitesi, and Ege Üniversitesi

Subjects
Microbiology (medical), SOAP, computer.internet_protocol, intensive care units, lcsh:Medicine, alcohol based disinfectants, Alcohol based disinfectants, Soap, lcsh:Infectious and parasitic diseases, paper towel, Intensive care, medicine, nosocomial infections, lcsh:RC109-216, Results of the Phokai Study-, MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.7, 2018 [Uyan A., Durmus G., Sezak N., Ozdemir B., Kaygusuz T., Oztoprak N., Ozdemir K., AKSOY F., Ozgultekin A., Koc M., et al., -Are Soap, Paper Towel and Alcohol-based Disinfectants Easily Accessible in Intensive Care Units in Turkey?], Intensive care units, General Immunology and Microbiology, lcsh:R, Paper towel, medicine.disease, Infectious Diseases, Medical emergency, Business, computer
Abstract

Introduction: Hand hygiene is one of the most effective infection control measures to prevent the spread of healthcare-associated infections (HCAI). Water, soap, paper towel and hand disinfectant must be available and adequate in terms of effective hand hygiene. The adequacy of hand hygiene products or keeping water-soap and paper towel is still a problem for many developing countries like Turkey. In this multicenter study, we analyzed the adequacy in number and availability of hand hygiene products., Materials and Methods: This study was performed in all intensive care units (ICUs) of 41 hospitals (27 tertiary-care educational, 10 state and four private hospitals) from 22 cities located in seven geographical regions of Turkey. We analyzed water, soap, paper towel and alcohol-based hand disinfectant adequacy on four different days, two of which were in summer during the vacation time (August, 27th and 31st 2016) and two in autumn (October, 12th and 15th 2016)., Results: The total number of ICUs and intensive care beds in 41 participating centers were 214 and 2357, respectively. Overall, there was no soap in 3-11% of sinks and no paper towel in 10-18% of sinks while there was no alcohol-based hand disinfectant in 1-4.7% of hand disinfectant units on the observation days. When we compared the number of sinks with soap and/or paper towel on weekdays vs. weekends, there was no significant difference in summer. However, on autumn weekdays, the number of sinks with soap and paper towel was significantly lower on weekend days (p, Conclusion: There should be adequate and accessible hand hygiene materials for effective hand hygiene. In this study, we found that soap and paper towels were inadequate on the observation days in 3-11% and 10-18% of units, respectively. Attention should be paid on soap and paper towel supply at weekends as well.

Published
2018

10. Türkiye’deki yoğun bakım ünitelerinde hemşire işgücü yeterli mi? Çok merkezli karia çalışmasının sonuçları

Author

Alpay Ari, Yeşim Kürekçi, Fatmanur Pepe, Handan Alay, Funda Kocak, Mehmet Uçar, Selçuk Özger, Türkkan Öztürk Kaygusuz, Serpil Erol, Rezan Harman, Ramazan Gözüküçük, Güleser Ünsal, Oğuz Reşat Sipahi, Sema Sarı, Ilknur Esen Yildiz, Gül Durmuş, Meliha Meriç Koç, Nefise Oztoprak, Kenan Uğurlu, Aslıhan Demirel, Sevil Alkan Çeviker, Şirin Menekşe, Güven Çelebi, Nilgün Doğan, Ayşe Uyan, Meltem Taşbakan, Firdevs Aksoy, Nurbanu Sezak, Mustafa Doğan, Hilal Sipahi, Pınar Firat, Kevser Ozdemir, Gunes Senol, Sercan Ulusoy, Bilgin Arda, Kübra Demiray, Derya Çağlayan, İrem Akdemir, Sabahat Çağan Aktaş, Ahsen Oncul, Mustafa Arslan, Haluk Erdoğan, Hulya Caskurlu, Özlem Kandemir, Habibe Tülin Elmaslar Mert, Emre Güven, Ege Üniversitesi, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Yıldız, İlknur Esen, Zonguldak Bülent Ecevit Üniversitesi, and MERİÇ KOÇ, MELİHA

Subjects
Microbiology (medical), Healthcare associated infections, Infection control, infection, healthcare-associated infections, intensive care infections, health care facilities, manpower, and services, education, lcsh:Medicine, Healthcare-associated infections, lcsh:Infectious and parasitic diseases, Nursing, Infection control practitioner, Intensive care, Medicine, lcsh:RC109-216, Intensive care infections, integumentary system, General Immunology and Microbiology, business.industry, lcsh:R, infection control practitioner, Infectious Diseases, Workforce, Uyan A., Durmus G., Sezak N., Pepe F., Kaygusuz T., Oztoprak N., Ozdemir K., AKSOY F., Erol S., Koc M., et al., -Is Nurse Workforce Sufficient in Intensive Care Units in Turkey. Results of the Multicenter Karia Study-, MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.6, 2017, business, Infection
Abstract

Introduction: In this multicenter study, we analysed the magnitude of healthcare worker (HCW) [infection control practitioner (ICP), nurses and others] workforce in hospitals participated in the study., Materials and Methods: This study was performed in 41 hospitals (with intensive care units-ICU) located in 22 cities from seven regions of Turkey. We analysed the ICP workforce, nursing and auxiliary HCW (AHCW) workforce in ICUs, number of ICU beds and occupied beds in four different days [two of which were in summer during the vacation time (August 27 and 31, 2016) and two others in autumn (October 12 and 15, 2016)]. The Turkish Ministry of Health (TMOH) requires two patients per nurse in level 3 ICUs, three patients per nurse in level 2 ICUs and five patients per nurse in level 1 ICUs. There is no standardization for the number of AHCW in ICUs. Finally, one ICP per 150 hospital beds is required by TMOH., Results: The total number of ICUs, ICU beds and ICPs were 214, 2377 and 111, respectively in he 41 participated centers. The number ICPs was adequate only in 12 hospitals. The percentage of nurses whose working experience was 2. The number of patients per other HCW was minimum 3.75 and maximum 4.89 on weekdays and on day shift while it was minimum 5.02 and maximum 7.7 on weekends or on night shift. When we compared the number of level 1, 2 and 3 ICUs with adequate nursing workforce vs inadequate nursing workforce, the p value was, Conclusion: Our data suggest that ICP workforce is inadequate in Turkey. Besides, HCW workforce is inadequate and almost 1/4 of nurses are relatively inexperienced especially in level 3 ICUs. Turkish healthcare system should promptly make necessary arrangements for adequate HCW staffing.

Published
2017

11. Surgical site infection rates in 16 cities in Turkey: findings of the International Nosocomial Infection Control Consortium (INICC)

Author

Ahmet Şahin, Iftihar Koksal, Gaye Usluer, Hülya Sungurtekin, Tanıl Kendirli, Selçuk Kaya, Eylul Gumus, Gürdal Yýlmaz, Mehmet Faruk Geyik, Ertugrul Guclu, Nurettin Erben, Tuna Demirdal, Tuncer Haznedaroglu, Huseyin Turgut, Levent Gorenek, Erdal Ince, Melek Güneş, Hava Yilmaz, Necdet Kuyucu, Suzan Sacar, Alper Şener, Oguz Dursun, Nefise Oztoprak, Ahmet Dilek, Fatma Sirmatel, Ergin Çiftçi, Meliha Meric, Gulsume Kaya, Mustafa Sunbul, Metin Otkun, Emel Azak, Fatma Ülger, Gülden Ersöz, Yunus Gürbüz, Ayşe Willke, Sehnaz Kaya, Hakan Leblebicioglu, Oral Oncul, Davut Ozdemir, Nevin Taşyapar, Ali Acar, Ediz Tutuncu, Zeynep Kaya, Doğaç Uğurcan, Oguz Karabay, Victor D. Rosenthal, Fazilet Duygu, Saban Esen, Ali Kaya, Ata Nevzat Yalcin, Hülya Ulusoy, Gunes Senol, Adem Karbuz, Turan Aslan, Özge Turhan, Selvi Erdogan, Cengiz Uzun, Ilhan Ozgunes, Leblebicioglu, H, Erben, N, Rosenthal, VD, Sener, A, Uzun, C, Senol, G, Ersoz, G, Demirdal, T, Duygu, F, Willke, A, Sirmatel, F, Oztoprak, N, Koksal, I, Oncul, O, Gurbuz, Y, Guclu, E, Turgut, H, Yalcin, AN, Ozdemir, D, Kendirli, T, Aslan, T, Esen, S, Ulger, F, Dilek, A, Yilmaz, H, Sunbul, M, Ozgunes, I, Usluer, G, Otkun, M, Kaya, A, Kuyucu, N, Kaya, Z, Meric, M, Azak, E, Yylmaz, G, Kaya, S, Ulusoy, H, Haznedaroglu, T, Gorenek, L, Acar, A, Tutuncu, E, Karabay, O, Kaya, G, Sacar, S, Sungurtekin, H, Ugurcan, D, Turhan, O, Gumus, E, Dursun, O, Geyik, MF, Sahin, A, Erdogan, S, Ince, E, Karbuz, A, Ciftci, E, Tasyapar, N, Gunes, M, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Güçlü, Ertuğrul, MERİÇ KOÇ, MELİHA, and Ondokuz Mayıs Üniversitesi

Subjects
Turkey, Epidemiology, Surgical wound infection, Health careeassociated infection, Turkey (republic), Cohort Studies, hip prosthesis, Nosocomial infection, Prospective Studies, hospital, Prospective cohort study, Health Policy, craniotomy, clinical trial, cohort analysis, Hospitals, hospital patient, Infectious Diseases, Cohort, Surgical site infection, Cohort study, prospective study, medicine.medical_specialty, Health care-associated infection, prevalence, education, infection rate, surgical infection, Article, Developing countries, coronary artery bypass graft, Internal medicine, medicine, Humans, Hospital infection, human, Cities, cesarean section, business.industry, Public Health, Environmental and Occupational Health, findings of the International Nosocomial Infection Control Consortium (INICC)-, AMERICAN JOURNAL OF INFECTION CONTROL, cilt.43, ss.48-52, 2015 [Leblebicioglu H., Erben N., ROSENTHAL V. D. , ŞENER A., UZUN C., SENOL G., Ersoz G., Demirdal T., DUYGU F., Willke A., et al., -Surgical site infection rates in 16 cities in Turkey], Nosocomial infection control, Confidence interval, shunting, Surgery, Clinical trial, multicenter study, city, business
Abstract

Yalcin, Ata Nevzat/0000-0002-7243-7354; dursun, oguz/0000-0001-5482-3780; Oncul, Oral/0000-0002-1681-1866; Leblebicioglu, Hakan/0000-0002-6033-8543; demirdal, tuna/0000-0002-9046-5666; Ciftci, Ergin/0000-0002-4955-160X; Erben, Nurettin/0000-0003-0373-0132; Kendirli, Tanil/0000-0001-9458-2803; Acar, Ali/0000-0003-2008-5112; Geyik, Mehmet Faruk/0000-0002-0906-0902; Dursun, Oguz/0000-0001-5482-3780; KAYA, ZEYNEP/0000-0002-8468-2103; KARABAY, OGUZ/0000-0003-1514-1685; Karabay, Oguz/0000-0003-0502-432X; Kaya, Sehnaz/0000-0003-0002-1517 WOS: 000347654600011 PubMed: 25564124 Background: Surgical site infections (SSIs) are a threat to patient safety; however, there were no available data on SSI rates stratified by surgical procedure (SP) in Turkey. Methods: Between January 2005 and December 2011, a cohort prospective surveillance study on SSIs was conducted by the International Nosocomial Infection Control Consortium (INICC) in 20 hospitals in 16 Turkish cities. Data from hospitalized patients were registered using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) methods and definitions for SSIs. Surgical procedures (SPs) were classified into 22 types according to International Classification of Diseases, Ninth Revision criteria. Results: We recorded 1879 SSIs, associated with 41,563 SPs (4.3%; 95% confidence interval, 4.3-4.7). Among the results, the SSI rate per type of SP compared with rates reported by the INICC and CDC NHSN were 11.9% for ventricular shunt (vs 12.9% vs 5.6%); 5.3% for craniotomy (vs 4.4% vs 2.6%); 4.9% for coronary bypass with chest and donor incision (vs 4.5 vs 2.9); 3.5% for hip prosthesis (vs 2.6% vs 1.3%), and 3.0% for cesarean section (vs 0.7% vs 1.8%). Conclusions: In most of the 22 types of SP analyzed, our SSI rates were higher than the CDC NHSN rates and similar to the INICC rates. This study advances the knowledge of SSI epidemiology in Turkey, allowing the implementation of targeted interventions. Copyright (C) 2015 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Published
2015

12. The course of spinal tuberculosis (Pott disease): results of the multinational, multicentre Backbone-2 study

Author

A. Batirel, H. Erdem, G. Sengoz, F. Pehlivanoglu, E. Ramosaco, S. Gülsün, R. Tekin, B. Mete, İ.İ. Balkan, D.Y. Sevgi, E. Giannitsioti, A. Fragou, S. Kaya, B. Cetin, T. Oktenoglu, A.D. Celik, B. Karaca, E.S. Horasan, M. Ulug, S. Senbayrak, E. Arslanalp, R. Hasbun, S. Ates-Guler, A. Willke, S. Senol, D. Inan, E. Güclü, G.T. Ertem, M.M. Koc, M. Tasbakan, G. Ocal, S. Kocagoz, H. Kusoglu, T. Güven, A.I. Baran, B. Dede, F.Y. Karadag, H. Yilmaz, G. Aslan, D.A. Al-Gallad, S. Cesur, R. El-Sokkary, F. Sirmatel, U. Savasci, G. Karaahmetoglu, H. Vahaboglu, OMÜ, Ege Üniversitesi, MERİÇ KOÇ, MELİHA, Acibadem University Dspace, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, and Sırmatel, Fatma

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, Adolescent, Endemic Diseases, International Cooperation, Antitubercular Agents, Kyphosis, Gibbus deformity, Scoliosis, Pott disease, Young Adult, Vertebral osteomyelitis, Humans, Medicine, Spondylitis, Aged, Retrospective Studies, Aged, 80 and over, Mediterranean Region, business.industry, Osteomyelitis, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, Spondylodiscitis, vertebral osteomyelitis, spondylitis, General Medicine, Middle Aged, medicine.disease, spinal tuberculosis, Survival Analysis, Surgery, ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS, Treatment Outcome, Infectious Diseases, ComputingMethodologies_PATTERNRECOGNITION, Surgical Procedures, Operative, Spinal tuberculosis, Female, Tuberculosis, Spinal, spondylodiscitis, InformationSystems_MISCELLANEOUS, business, Paraplegia
Abstract

PubMed ID: 26232534, We aimed to describe clinical, laboratory, diagnostic and therapeutic features of spinal tuberculosis (ST), also known as Pott disease. A total of 314 patients with ST from 35 centres in Turkey, Egypt, Albania and Greece were included. Median duration from initial symptoms to the time of diagnosis was 78 days. The most common complications presented before diagnosis were abscesses (69%), neurologic deficits (40%), spinal instability (21%) and spinal deformity (16%). Lumbar (56%), thoracic (49%) and thoracolumbar (13%) vertebrae were the most commonly involved sites of infection. Although 51% of the patients had multiple levels of vertebral involvement, 8% had noncontiguous involvement of multiple vertebral bodies. The causative agent was identified in 41% of cases. Histopathologic examination was performed in 200 patients (64%), and 74% were consistent with tuberculosis. Medical treatment alone was implemented in 103 patients (33%), while 211 patients (67%) underwent diagnostic and/or therapeutic surgical intervention. Ten percent of the patients required more than one surgical intervention. Mortality occurred in 7 patients (2%), and 77 (25%) developed sequelae. The distribution of the posttreatment sequelae were as follows: 11% kyphosis, 6% Gibbus deformity, 5% scoliosis, 5% paraparesis, 5% paraplegia and 4% loss of sensation. Older age, presence of neurologic deficit and spinal deformity were predictors of unfavourable outcome. ST results in significant morbidity as a result of its insidious course and delayed diagnosis because of diagnostic and therapeutic challenges. ST should be considered in the differential diagnosis of patients with vertebral osteomyelitis, especially in tuberculosis-endemic regions. Early establishment of definitive aetiologic diagnosis and appropriate treatment are of paramount importance to prevent development of sequelae. © 2015 European Society of Clinical Microbiology and Infectious Diseases.

Published
2015

13. International Nosocomial Infection Control Consortium (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

Author

Víctor Daniel Rosenthal, Dennis George Maki, Yatin Mehta, Hakan Leblebicioglu, Ziad Ahmed Memish, Haifaa Hassan Al-Mousa, Hanan Balkhy, Bijie Hu, Carlos Alvarez-Moreno, Eduardo Alexandrino Medeiros, Anucha Apisarnthanarak, Lul Raka, Luis E. Cuellar, Altaf Ahmed, Josephine Anne Navoa-Ng, Amani Ali El-Kholy, Souha Sami Kanj, Ider Bat-Erdene, Wieslawa Duszynska, Nguyen Van Truong, Leonardo N. Pazmino, Lucy Chai See-Lum, Rosalia Fernández-Hidalgo, Gabriela Di-Silvestre, Farid Zand, Sona Hlinkova, Vladislav Belskiy, Hussain Al-Rahma, Marco Tulio Luque-Torres, Nesil Bayraktar, Zan Mitrev, Vaidotas Gurskis, Dale Fisher, Ilham Bulos Abu-Khader, Kamal Berechid, Arnaldo Rodríguez-Sánchez, Florin George Horhat, Osiel Requejo-Pino, Nassya Hadjieva, Nejla Ben-Jaballah, Elías García-Mayorca, Luis Kushner-Dávalos, Srdjan Pasic, Luis E. Pedrozo-Ortiz, Eleni Apostolopoulou, Nepomuceno Mejía, May Osman Gamar-Elanbya, Kushlani Jayatilleke, Miriam de Lourdes-Dueñas, Guadalupe Aguirre-Avalos, Diego Marcelo Maurizi, Adriana Montanini, Maria Laura Spadaro, Lorenzo Santiago Marcos, Priscila Botta, Florencia Maria Jerez, Maria Constanza Chavez, Lucia Ramasco, Maria Isabel Colqui, Maria Silvia Olivieri, Ana Silvia Rearte, Gladys Edith Correa, Paola Deolinda Juarez, Paola Fabiana Gallardo, Miriam Patricia Brito, Gabriel Horacio Mendez, Julia Rosa Valdez, Lorena Paola Cardena, Jose Maria Harystoy, Gustavo Jorge Chaparro, Claudia Gabriela Rodriguez, Rodolfo Toomey, Maria Caridi, Monica Viegas, Marisa Liliana Bernan, Adriana Romani, Claudia Beatriz Dominguez, Luis Kushner Davalos, Rosana Richtmann, Camila Almeida Silva, Tatiane T. Rodrigues, Amaury Mielle Filho, Ernandi Dagoberto Seerig Palme, Aline Besen, Caroline Lazzarini, Caroline Batista Cardoso, Francisco Kennedy Azevedo, Ana Paula Fontes Pinheiro, Aparecida Camacho, Braulio Matias De Carvalho, Maria Jose Monteiro De Assis, Ana Paula Vasconcelos Carneiro, Maria Lilian Maciel Canuto, Keyla Harten Pinto Coelho, Tamiris Moreira, Agamenon Alves Oliveira, Marcela Maria Sousa Colares, Marcia Maria De Paula Bessa, Tereza De Jesus Pinheiro Gomes Bandeira, Renata Amaral De Moraes, Danilo Amâncio Campos, Tânia Mara Lima De Barros Araújo, Maria Tereza Freitas Tenório, Simone Amorim, Manuela Amaral, Julianne Da Luz Lima, Lindalva Pino Da Silva Neta, Caphiane Batista, Fabio Jorge De Lima Silva, Maria C. Ferreira De Souza, Katia Arruda Guimaraes, Julia Marcia Maluf Lopes, Karina M. Nogueira Napoles, Lorena Luiza Silva Neto Avelar, Lilian Aguiar Vieira, Luis Gustavo De Oliveira Cardo, Christianne F.V. Takeda, Glaydson A. Ponte, Fco Eduardo Aguiar Leitão, Ricardo De Souza Kuchenbecker, Rodrigo Pires Dos Santos, Erci Maria Onzi Siliprandi, Luiz Fernando Baqueiro Freitas, Ianick Souto Martins, Daiane Casi, Maria Angela Maretti Da Silva, Sergio Blecher, Margarete Villins, Reinaldo Salomao, Solange Regina Oliveira Castro, Daniela V. Da Silva Escudero, Mariana Andrade Oliveira Reis, Marcelo Mendonca, Valter Furlan, Antonio Claudio do Amaral Baruzzi, Tarquino Eristidesg Sanchez, Marina Moreira, Wania Vasconcelos de Freitas, Leonardo Passos de Souza, Velmira Angelova Velinova, Michael M. Petrov, Dimitar Georgiev Karadimov, Emil D. Kostadinov, Violeta Jivkova Dicheva, Chaohua Wang, Xiuqin Guo, Xihua Geng, Shufang Wang, Jinzhi Zhang, Ling Zhu, Shufang Zhuo, Chunli Guo, Tao Lili, Li Ruisheng, Liu Kun, Xuesong Yang, Li Yimin, Mao Pu, Li Changan, Yiang Shumei, Wu Kangxiong, Lin Meiyi, Guxiang Ye, Xu Ziqin, Suo Yao, Song Liqiang, Luis Marino Cañas Giraldo, Elsa Margarita Trujillo Ramirez, Paola Andrea Rios, Juan Carlos Torres Millan, Edwin Giovanny Chapeta Parada, Andres Eduardo Mindiola Rochel, Andres H. Corchuelo Martinez, Ana Marãa Perez Fernandez, Nayide Barahona Guzman, Alfredo Lagares Guzman, Marena Rodriguez Ferrer, Yazmin Leon Vega, Heidi Johanna Munoz, Germán Camacho Moreno, Sandra Liliana Romero Torres, Herlidia Taboada Hernandez, Ismael A. Valderrama MarquezClaudia Linares, Monica Espinosa Valencia, Lusayda Sanchez Corrales, Sandra Milena Bonilla, Jorge Ivan Marin Uribe, David Yepes Gomez, Javier Ospina Martinez, Luz Dary Burgos Florez, Johanna Osorio, Dagoberto Santofimio, Lorena Matta Cortes, Wilmer Villamil-Gomez, Gabriel Munoz Gutierrez, Adela Arguello Ruiz, Carlos Gonzalez Fuentes, Antonio Solano Chinchilla, Ivar Calvo Hernandez, Olber Chavarria Ugalde, Humberto Guanche Garcell, Clara Morales Perez, Selin Bardak, Sumru Ozkan, Nepomuceno Mejia, Adrian M. Puello Guerrero Glenny Mirabal, Margarita Delgado, Ramona Severino, Eliesel Lacerda, Gilda Tolari, María Marcela Bovera, Diego Barahona Pinto, Pedro Fernández González, Gasdali Santacruz, Nelly Alquinga, Celso Zaruma, Nelson Remache, Diego Morocho, Mario Arboleda, Mario Cadena Zapata, Maria Fernanda Garcia, Fabricio Picoita, Jorge Velez, Marcia Valle, Estuardo Salgado Yepez, Diego Morocho Tutillo, Ricardo Arteaga Mora, Andrea Peña Padilla, Mayra Chango, Karina Cabezas, Shirley Tenorio López, Ana Lucía Bonilla Escudero, Gladys Tatiana Sánchez, Hugo Alberto Gonzalez Flores, Islam Abdullorziz Ghazi, Mohamed Hassan, Ghada A. Ismail, Reham Hamed, Mona Mohiedden Abdel-Halim, May Abd El-Fattah, Doaa Abdel-Aziz, Zeinab Salah Seliem, Rasha Hamed Elsherif, Reham Ali Dewdar, Abeer Ahmed Mohmed, Lamiaa Abdel-Fatteh Ahmed, Lilian De Jesus Machuca, Concepcion Bran De Casares, Prokopis Kithreotis, Maria Daganou, Dimitrios Veldekis, Maria Kartsonaki, Achilleas Gikas, Marco Tulio Luque Torres, Denis Padgett, Doris Maribel Rivera, Namita Jaggi, Camilla Rodrigues, Bhagyesh Shah, Keyur Parikh, Jigar Patel, Riya Thakkar, Murali Chakravarthy, B.N. Gokul, R. Sukanya, Leema Pushparaj, Thejas Vini, Sukanya Rangaswamy, Saroj Kumar Patnaik, Vempati Venkateshwar, Biju John, Shamsher Dalal, Suneeta Sahu, Samir Sahu, Banambar Ray, Sudhiranjan Misra, Nisith Mohanty, Biraj Mohan Mishra, Prafulla Sahoo, Naresh Parmar, Sanghamitra Mishra, Basanta Kumar Pati, Santosh Singh, Bhabani Shankar Pati, Aparajita Panda, Swarna Banergee, Dipankar Padhihari, Soumya Samal, Karthikeya Varma, Velu Pandi Suresh Kumar, Ram Gopalakrishnan, Nagarajan Ramakrishnan, Babu Kuruvilla Abraham, Senthilkumar Rajagopal, Ramesh Venkatraman, Ashwin Kumar Mani, Dedeepiya Devaprasad, Lakshmi Ranganathan, Thara Francis, Kotturathu Mammen Cherain, Bala Ramachandran, Ravikumar Krupanandan, S. Muralidharan, Murali Karpagam, Baby Padmini, S. Saranya, Siva Kumar, Nirav Pandya, Rajesh Kakkar, Tenzin Zompa, Narinder Saini, Srinivas Samavedam, Ganshyam Jagathkar, Suhas Nirkhiwale, G.S. Gehlot, Shefali Bhattacharya, Sanjeev Sood, Suman Singh, Sanjeev Singh, Subhash Kumar Todi, Mahuya Bhattacharyya, Arpita Bhakta, Susmita Basu, Anuradha Agarwal, Manoj Agarwal, Mohit Kharbanda, Sankar Sengupta, Anirban Karmakar, Debkishore Gupta, Ajoy Krishna Sarkar, Rimita Dey, Chandramouli Bhattacharya, Mammen Chandy, V.R. Ramanan, Aseem Mahajan, Manas Roy, Sanjay Bhattacharya, Saswati Sinha, Indranil Roy, Umesh Gupta, Sujoy Mukherjee, Mrinmoy Bej, Purnima Mukherjee, Sumana Baidya, Afzal Azim, Asmita Sagar Sakle, Jehangir Soli Sorabjee, Mrunalini Subhash Potdar, Vaibhavi R. Subhedar, F.E. Udwadia, Hena Francis, Arpita Dwivedy, Sheena Binu, Suvin Shetty, Pravin Kumar Nair, Devendra K. Khanna, Felcy Chacko, Seelas Blessymole, Preeti Rajeev Mehta, Tanu Singhal, Sweta Shah, Vatsal Kothari, Reshma Naik, Mayur Harshadrai Patel, Deepesh Gokulchand Aggarwal, Burhanuddin Qutbuddin Jawadwala, Niketa Kaul Pawar, Shoeb Nizamuddin Kardekar, Abizer Nuruddin Manked, S.N. Myatra, J.V. Divatia, R. Kelkar, S.K. Biswas, V. Raut, S. Sampat, Alka Thool, Anil Karlekar, Sumi Nandwani, Sudhir Gupta, Sanjay Singhal, Madhu Gupta, Purva Mathur, Subodh Kumar, Kavita Sandhu, Arnab Dasgupta, Abhijeet Raha, Padmalatha Raman, Ashoo Wadhera, Binesh Badyal, Sarika Juneja, Bikas Mishra, Sunil Sharma, Megha Mehrotra, Jayant Shelgaonkar, Vikram Padbidri, Rohini Dhawale, Sheena Mary Sibin, Dileep Mane, Hanamant Kashinath Sale, Mohammad Mukhit Abdul Gaffar Kazi, Supriya Chabukswar, Anju Mathew, Dipti Gaikwad, Amol Harshe, Gita Nadimpalli, Sunil Bhamare, Soniya Thorat, Omnarayan Sarda, Pattabhiramarao Nadimpalli, Angelina Mendonca, Sujata Malik, Asmita Kamble, Nilakshi Kumari, Sohini Arora, Nita Munshi, Deepa Ganesh Divekar, Maithili Satish Kavathekar, Anuja Kedar Kulkarni, Madhupriya Vijay Suryawanshi, Madhavi Latha Bommala, Anil Bilolikar, Kashmira Limaye Joshi, Charulata Pamnani, Harvinder Wasan, Sonali Khamkar, Leena Steephen, Arjun Rajalakshmi, Anzar Thair, Aisha Mubarak, Swathy Sathish, Suresh Kumar, H. Sunil, Sujith Sujith, null Dinesh, Nagamani Sen, Nitin Shinde, Masoud Alebouyeh, Somayeh Jahani-Sherafat, Mohammad Reza Zali, Mohammad Reza Sarbazi, Nahid Mansouri, Elahe Tajeddin, Maryam Razaghi, Simasadat Seyedjavadi, Marjan Rashidan, Mansoor Masjedi, Behzad Maghsudi, Golnar Sabetian, Anahita Sanaei, Atefeh Yousefipour, Abdullah Mufareh Assiri, Elaine Mari Furukawa-Cinquini, Areej Dhafer Alshehri, Alysia Faye Giani, Nadia Lynette Demaisip, Elizabeth Laungayan Cortez, Analen Fabros Cabato, Jerlie Mae Gonzales Celiz, Ibrahim A.M. Al-Zaydani Asiri, Yassir Khidir Mohammed, Mohammed Abdullah Al Raey, Ali Omer Abdul Aziz, Saeed Ali Al Darani, Misbah Rehman Aziz, Roaa Hasan Basri, Duaa Khalil Al-Awadi, Syed Zahid Bukhari, Rosita Gasmin Aromin, Evangelina Balon Ubalde, Apsia Musa Molano, Hessa Abdullah Al Enizy, Celia Flores Baldonado, Fatima Mohammad Al Adwani, Arlu Marie Casuyon Pahilanga, Avigail M. Tan, Sonia Joseph, Deepa Sasidharan Nair, Nabeela Abdullah Al-Abdullah, Grace Sindayen, Annalyn Amor Malificio, Diaa Abdullah Mohammed, Hanan Mesfer Al Ghamdi, Ameurfina Curioso Silo, Marianina Brenda V. Valisto, Nektarios Foteinakis, Sameeh Salem Ghazal, Mercy V. Joseph, Ahmed Hakawi, Antigona Hasani, Ismet Jusufi, Gazmend Spahija, Nehat Baftiu, Agreta Gecaj-Gashi, Nasser Yehia Aly, Mohammad El-Dossoky Noweir, Suga Thomas Varghese, Ruby Jose Ramapurath, Amna Mostafa Mohamed, Sneha Mary George, Anu Kurian, Amani Fouad Sayed, Mona Foda Salama, Abeer Aly Omar, Flavie Maria Rebello, Dennis Malungcot Narciso, Nada Kara Zahreddine, Zeina Kanafani, Tala Kardas, Bassel Molaeb, Lamia Jurdi, Anwar Al Souheil, Mohamad Ftouni, Hasan Ayash, Tahsine Mahfouz, Tomas Kondratas, Dovile Grinkeviciute, Rimantas Kevalas, Greta Gailiene, Algirdas Dagys, Milena Petrovska, Katja Popovska, Zaneta Bogoevska-Miteva, Katerina Jankovska, Snezana Tufekcievska Guroska, Tanja Anguseva, Wan Nurbayah Wan Yusoff, Anis Shiham Zainal Abidin, Chin Seng Gan, Hasimah Zainol, Vineya Rai, Wong Kang Kwong, Mohd Shahnaz Hasan, Sasheela Sri La Sri Ponnampala, Jeyaganesh Veerakumaran, Ojan Assadian, Doan Mai Phuong, Nguyen Gia Binh, Kerinjeet Kaur, Joelene Lim, Lian-Huat Tan, Jegathesan Manikavasagam, Yuet-Meng Cheong, Hilario Coronado Magaña, Julio Cesar Mijangos Méndez, Federico Corona Jiménez, Sergio Esparza-Ahumada, Rayo Morfin-Otero, Eduardo Rodriguez-Noriega, Susana Gutierrez-Martinez, Hector Raul Perez-Gomez, Gerardo León-Garnica, Christian Mendoza-Mujica, Martha Cecilia Culebro Burguet, Jorge Horacio Portillo-Gallo, Fernando Aguilera Almazán, Gaspar Iglesias Miramontes, Maria del Rosario Vázquez Olivas, Lucio Alberto Aguilar Angel, Marisol Sanchez Vargas, Angel Orlando Flores Alvarado, Roberto Carlos Mares Morales, Luis Carlos Fernandez Alvarez, Hector Armando Rincon Leon, Karla Reyna Navarro Fuentes, Yuri Mariela Perez Hernandez, Gabriela Martinez Falcon, Angel Gonzalez Vargas, Marco A. Trujillo Juarez, Antonio Martinez Mulia, Paulina Alma Ulloa Camacho, Martha Y. Martinez-Marroquin, Marco Montell Garcia, Araceli Martinez Martinez, Elena Leon Sanchez, Guadalupe Gomez Flores, Marisela del Rocío González Martínez, Jesús Alfonso Galindo Olmeda, Georgina Olivarez, Enrique Barbachano Rodriguez, María Magdalena Gutierrez Castillo, María Guadalupe Villa González, Isaura Beatriz Sauceda Castañeda, Jaime Martínez Rodriguez, Otgon Baatar, Byambadorj Batkhuu, Kabiri Meryem, Barkat Amina, Rédouane Abouqal, Amine Ali Zeggwagh, Tarek Dendane, Khalid Abidi, Naoufel Madani, Syed Faisal Mahmood, Badaruddin A. Memon, Gul Hassan Bhutto, Nadeem Paul, Azra Parveen, Aun Raza, Amjad Mahboob, Summiya Nizamuddin, Faisal Sultan, Hammad Nazeer, Ashraf Ali Khan, Arifa Hafeez, Lydia Lara, Trudell Mapp, Balkys Alvarez, Magda Ivonne Rojas-Bonilla, Elizabeth Castano, Daisy A. De Moros, Roberto Espinoza Atarama, Maria Elena Calisto Pazos, Alfredo Paucar, Marlene Tasayco Ramos, Jenny Jurado, Dafne Moreno, Marãa E. Cruz Saldarriaga, Eliza Ramirez, Carlos Enrique La Hoz Vergara, Walter Enrique Prudencio Leon, Luis Isidro Castillo Bravo, Katya Fernanda Aibar Yaranga, Janet E. Pichilingue Chagray, Vanessa A. Marquez Mondalgo, Socorro Torres Zegarra, Nazario Silva Astete, Francisco Campos Guevara, Javier Soto Pastrana, Carlos F. Linares Calderon, Manuel Jesus Mayorga Espichan, Luis Martin Santivanez Monge, Maria V. Changano Rodriguez, Zoila Rosa Diaz Tavera, Fernando Martin Ramirez Wong, Selene Manga Chavez, Teodora Atencio-Espinoza, Victoria D. Villanueva, Maria Teresa Blanco-Abuy, Arnefelina S. Tamayo, Lailane D. Bergosa, Cristina Mari Jean P. Llames, Marilou F. Trajano, Suzette A. Bunsay, Jessica C. Amor, Regina Berba, Maria Carmen Sg Buenaflor, Ever Labro, Myrna T. Mendoza, Ofelia P. Javellana, Lilibeth G. Salvio, Rhoda Gay Rayco, Vanessa Bermudez, Andrzej Kubler, Marzena Zielinska, Magdalena Kosmider-Zurawska, Barbara Barteczko-Grajek, Ewa Szewczyk, Barbara Dragan, Malgorzata Anna Mikaszewska-Sokolewicz, Tomasz Lazowski, Elsie Cancel, Monica Sorina Licker, Liliana Alina Dragomirescu, Victor Dumitrascu, Dorel Sandesc, Ovidiu Bedreag, Marius Papurica, Delia Muntean, Igor Kotkov, Vladimir Kretov, Vladimir Shalapuda, Alexander Molkov, Sergey Puzanov, Ivan Utkin, Alexander Tchekulaev, Valentina Tulupova, Ljubica Nikolic, Goran Ristic, Jelena Eremija, Jelena Kojovic, Dragana Lekic, Sladjana Vasiljevic, Anna Lesnakova, Alzbeta Marcekova, Katarina Furova, May Osman Gamar Elanbya, Malik Abdo Ali, Shobhana Kumari Kadankunnel, Suwara Somabutr, Rungratchanee Pimathai, Suthinee Wanitanukool, Montri Luxsuwong, Namphon Supa, Pornpheth Prasan, Visanu Thamlikitkul, Silom Jamulitrat, Nonglak Suwalak, Parichart Phainuphong, Bouziri Asma, Borgi Aida, Bel Hadj Sarra, Khaldi Ammar, Gunay Tuncer Ertem, Cemal Bulut, Cigdem Ataman Hatipoglu, Fatma Sebnem Erdinc, Ali Pekcan Demiroz, Menekse Ozcelik, Basak Ceyda Meco, Mehmet Oral, Necmettin Unal, Cigdem Yildirim Guclu, Tanıl Kendirli, Erdal İnce, Ergin Çiftçi, Ayhan Yaman, Çağlar Ödek, Adem Karbuz, Bilge Aldemir Kocabaş, Nilgün Altın, Salih Cesur, Begum Atasay, Omer Erdeve, Hasan Akduman, Dilek Kahvecioglu, Ufuk Cakir, Duran Yildiz, Atila Kilic, Saadet Arsan, Dilek Arman, Serhat Unal, Yasemin Gelebek, Humeyra Zengin, Suha Sen, Hatice Cabadak, Ayse Erbay, Ata Nevzat Yalcin, Ozge Turhan, Melike Cengiz, Oguz Dursun, Perihan Gunasan, Sehnaz Kaya, Atilla Ramazanoglu, Cemal Ustun, Aliye Yasayacak, Hayrettin Akdeniz, Fatma Sirmatel, Ali Metin Otkun, Suzan Sacar, Alper Sener, Huseyn Turgut, Hulya Sungurtekin, Dogaç Ugurcan, Ceyda Necan, Cansu Yilmaz, Davut Ozdemir, Mehmet Faruk Geyik, Nevin Ince, Ayse Danis, Selvi Yener Erdogan, Nurettin Erben, Gaye Usluer, Ilhan Ozgunes, Cengiz Uzun, Oral Oncul, Levent Gorenek, Hakan Erdem, Orhan Baylan, Asu Ozgultekin, Asuman Inan, Sibel Bolukcu, Gunes Senol, Halil Ozdemir, Zeynel Gokmen, Sonay Incesoy Ozdemir, Ali Kaya, Gulden Ersoz, Necdet Kuyucu, Sevim Karacorlu, Zeynep Kaya, Ertugrul Guclu, Gulsume Kaya, Oguz Karabay, Saban Esen, Canan Aygun, Fatma Ulger, Ahmet Dilek, Hava Yilmaz, Mustafa Sunbul, Aynur Engin, Mehmet Bakir, Nazif Elaldi, Iftihar Koksal, Dincer Yildizdas, Ozden Ozgur Horoz, Ayşe Willke, Meliha Meriç Koç, Emel Azak, Naheed Elahi, Philip Annamma, Ashraf El Houfi, Maria Catalina Pirez Garcia, Hector Vidal, Fernando Perez, Gabriel D. Empaire, Yvis Ruiz, Dulce Hernandez, Dayana Aponte, Evelyn Salinas, Claudia Diaz, María Eugenia Guzmán Siritt, Zenaida Durán Gil De Añez, Luis Montes Bravo, Nelva Orozco, Eugenia Mejías, Nguyen Viet Hung, Nguyen Quoc Anh, Ngo Quy Chau, Truong Anh Thu, Le Thi Diem Tuyet, Dang Thi Van Trang, Vo Thi Hong Thoa, Nguyen Phuc Tien, Le Thi Anh Thu, Phan Thi Hang, Tran Thi My Hanh, Tran Thi Thuy Hang, Dinh Pham Phuong Anh, Ondokuz Mayıs Üniversitesi, KILIÇ, ATİLA, and MERİÇ KOÇ, MELİHA

Subjects
Imipenem, medicine.medical_specialty, Pediatrics, Low income countries, Asia, Epidemiology, Klebsiella pneumoniae, Health care-associated infection, Antibiotic resistance, Catheter-associated urinary tract infection, Ceftazidime, Network, Bloodstream infection, Developing countries, Nosocomial infection, Intensive care, medicine, Ventilator-associated pneumonia, Humans, Hospital infection, Prospective Studies, Urinary tract infection, Cross Infection, Infection Control, biology, business.industry, Health Policy, Public Health, Environmental and Occupational Health, medicine.disease, Nosocomial infection control, biology.organism_classification, Device-associated infection, United States, Europe, Pneumonia, Intensive Care Units, Infectious Diseases, Latin America, Amikacin, Emergency medicine, Africa, Limited resources countries, Central line-associated bloodstream infections, Centers for Disease Control and Prevention, U.S, business, medicine.drug
Abstract

Maghsoudi, Behzad/0000-0002-1279-8799; Kritsotakis, Evangelos/0000-0002-9526-3852; Yalcin, Ata Nevzat/0000-0002-7243-7354; Mikaszewska-Sokolewicz, Malgorzata A/0000-0002-1148-7817; ALDEMIR KOCABAS, Bilge/0000-0002-6396-5243; Masjedi, Mohammad Reza/0000-0002-6871-382X; Masjedi, Mansoor/0000-0001-6175-9289; Gan, Chin Seng/0000-0002-6758-4798; Oncul, Oral/0000-0002-1681-1866; Sabetian, Golnar/0000-0001-8764-2150; YAMAN, Ayhan/0000-0002-5651-1286; Ozdemir, Halil/0000-0002-7318-1688; Leon, Hector Armando Rincon/0000-0003-0715-200X; Delia, Muntean/0000-0001-9100-4530; Atasay, Fatma Begum/0000-0002-9114-5293; Zand, Farid/0000-0003-3489-3372; Kuchenbecker, Ricardo/0000-0002-4707-3683; Medeiros, Eduardo A/0000-0002-6205-259X; ROMERO LOPEZ-ALBERCA, CRISTINA/0000-0001-5856-8668; Salomao, Reinaldo/0000-0003-1149-4598; ozdemir, sonay incesoy/0000-0003-2863-901X; Meco, Basak Ceyda/0000-0003-2951-9634; Horoz, Ozden Ozgur/0000-0001-7590-650X; Horhat, Florin George/0000-0001-6133-0204; Kazi, Mohammad Mukhit/0000-0003-3824-5540; Ciftci, Ergin/0000-0002-4955-160X; Abouqal, Redouane/0000-0002-6117-4341; Leblebicioglu, Hakan/0000-0002-6033-8543; Garcell, Humberto Guanche/0000-0001-7279-0062; Kendirli, Tanil/0000-0001-9458-2803; de Souza, Maria Cecilia B V/0000-0003-0318-3087; Sanaei Dashti, Anahita/0000-0002-2827-3575; UNAL, SERHAT/0000-0003-1184-4711; alvarez Moreno, carlos Arturo/0000-0001-5419-4494; Barahona G., Nayide/0000-0003-3559-6900; Rodriguez Ferrer, Marena Luz/0000-0002-8053-8454; Karabay, Oguz/0000-0003-0502-432X; Kaya, Sehnaz/0000-0003-0002-1517; ERDEVE, OMER/0000-0002-3193-0812; Gonzalez Martinez, Marisela del Rocio/0000-0003-1474-736X; Gikas, Achilleas/0000-0002-8455-9631; Baylan, Orhan/0000-0002-6529-7824; Mitrev, Zan/0000-0001-7859-8821; yildizdas, dincer/0000-0003-0739-5108; Ngo, Quy Chau/0000-0002-6787-2757; Duszynska, Wieslawa/0000-0002-5880-4904; KAYA, ZEYNEP/0000-0002-8468-2103; Dragan, Barbara/0000-0003-3108-4211; Gupta, Umesh/0000-0001-7717-1404; Navarro Fuentes, Karla Reyna/0000-0002-6894-8872; zali, Mohammadreza/0000-0002-9027-4560; Morocho Tutillo, Diego Rolando/0000-0002-4974-7856; El Kholy, Amani/0000-0002-0645-7664; Kanj, Souha/0000-0001-6413-3396; Assiri, Abdullah/0000-0002-5605-2876; Unal, Necmettin/0000-0002-9440-7893; Jayatilleke, Kushlani/0000-0002-3931-6630; KARABAY, OGUZ/0000-0003-1514-1685 WOS: 000341307100001 PubMed: 25179325 We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line-associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U. S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN. Copyright (C) 2014 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Published
2014

14. International Nosocomial Infection Control Consortium (INICC) national report on device-associated infection rates in 19 cities of Turkey, data summary for 2003-2012

Author

Leblebicioglu, Hakan, Erben, Nurettin, Rosenthal, Victor Daniel, Atasay, Begum, Erbay, Ayse, Unal, Serhat, Senol, Gunes, Willke, Ayse, Ozgultekin, Asu, Altin, Nilgun, Bakir, Mehmet, Oncul, Oral, Ersoz, Gulden, Ozdemir, Davut, Yalcin, Ata Nevzat, Ozdemir, Halil, Yildizdas, Dincer, Koksal, Iftihar, Aygun, Canan, Sirmatel, Fatma, Sener, Alper, Tuna, Nazan, Akan, OTzay Arikan, Turgut, Huseyin, Demiroz, A. Pekcan, Kendirli, Tanil, Alp, Emine, Uzun, Cengiz, Ulusoy, Sercan, Arman, Dilek, Ozgunes, Ilhan, Usluer, Gaye, Kilic, Atila, Arsan, Saadet, Cabadak, Hatice, Sen, Suha, Gelebek, Yasemin, Zengin, Humeyra, Topeli, Arzu, Alper, Yusuf, Meric, Meliha, Azak, Emel, Inan, Asuman, Turan, Guldem, Haznedaroglu, Tuncer, Gorenek, Levent, Acar, Ali, Cesur, Salih, Engin, Aynur, Kaya, Ali, Kuyucu, Necdet, Geyik, Mehmet Faruk, Aydin, Ozlem Cetinkaya, Erdogan, Nurse Selvi, Turhan, Ozge, Gunay, Nurgul, Gumus, Eylul, Dursun, Oguz, Esen, Saban, Ulger, Fatma, Dilek, Ahmet, Yilmaz, Hava, Sunbul, Mustafa, Gokmen, Zeynel, Ozdemir, Sonay Incesoy, Horoz, Ozden Ozgur, Yylmaz, Gurdal, Kaya, Selcuk, Ulusoy, Hulya, Kucukoduk, Sukru, Ustun, Cemal, Baysal, Abant Izzet, Otkun, Metin, Tulunay, Melek, Oral, Mehmet, Unal, Necmettin, Cengiz, Mustafa, Yilmaz, Leyla, Sacar, Suzan, Sungurtekin, Hulya, Ugurcan, Dogac, Yetkin, M. Arzu, Bulut, Cemal, Erdinc, F. Sebnem, Hatipoglu, Cigdem Ataman, Ince, Erdal, Ciftci, Ergin, Odek, Caglar, Yaman, Ayhan, Karbuz, Adem, Aldemir, Bilge, Kilic, Aysegul Ulu, Arda, Bilgin, Bacakoglu, Feza, Hizel, Kenan, [Leblebicioglu, Hakan -- Esen, Saban -- Ulger, Fatma -- Dilek, Ahmet -- Yilmaz, Hava -- Sunbul, Mustafa] Ondokuz Mayis Univ, Sch Med, Samsun, Turkey -- [Erben, Nurettin -- Ozgunes, Ilhan -- Usluer, Gaye] Eskisehir Osmangazi Univ, Eskisehir, Turkey -- [Rosenthal, Victor Daniel] Int Nosocomial Infect Control Consortium, Ave 4580,Floor 12,Apt D, RA-1195 Buenos Aires, DF, Argentina -- [Atasay, Begum -- Kilic, Atila -- Arsan, Saadet] Ankara Univ, Sch Med, Fac Paediat, Dept Newborn Med, TR-06100 Ankara, Turkey -- [Erbay, Ayse -- Cabadak, Hatice -- Sen, Suha] Turkiye Yuksek Ihtisas Educ & Res Hosp, Ankara, Turkey -- [Unal, Serhat -- Gelebek, Yasemin -- Zengin, Humeyra -- Topeli, Arzu -- Alper, Yusuf] Hacettepe Univ, Sch Med, Ankara, Turkey -- [Senol, Gunes] Suat Seren Chest Dis & Chest Surg Training Hosp, Izmir, Turkey -- [Willke, Ayse -- Meric, Meliha -- Azak, Emel] Kocaeli Univ, Fac Med, Kocaeli, Turkey -- [Ozgultekin, Asu -- Inan, Asuman -- Turan, Guldem] Haydarpasa Numune Training & Res Hosp, Istanbul, Turkey -- [Altin, Nilgun -- Cesur, Salih] Etlik Ihtisas Training & Educ Hosp, Ankara, Turkey -- [Bakir, Mehmet -- Engin, Aynur] Cumhuriyet Univ, Sch Med, Sivas, Turkey -- [Oncul, Oral -- Haznedaroglu, Tuncer -- Gorenek, Levent -- Acar, Ali] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Istanbul, Turkey -- [Ersoz, Gulden -- Kaya, Ali -- Kuyucu, Necdet] Mersin Univ, Fac Med, Mersin, Turkey -- [Ozdemir, Davut -- Geyik, Mehmet Faruk -- Aydin, Ozlem Cetinkaya -- Erdogan, Nurse Selvi] Duzce Univ, Med Sch Infect Dis & Clin Microbiol, Duzce, Turkey -- [Yalcin, Ata Nevzat -- Turhan, Ozge -- Gunay, Nurgul -- Gumus, Eylul -- Dursun, Oguz] Akdeniz Univ, TR-07058 Antalya, Turkey -- [Ozdemir, Halil -- Gokmen, Zeynel -- Ozdemir, Sonay Incesoy] Konya Training & Res Hosp, Konya, Turkey -- [Yildizdas, Dincer -- Horoz, Ozden Ozgur] Cukurova Univ, Balcali Hosp, Adana, Turkey -- [Koksal, Iftihar -- Yylmaz, Gurdal -- Kaya, Selcuk -- Ulusoy, Hulya] Karadeniz Tech Univ, Sch Med, Trabzon, Turkey -- [Aygun, Canan -- Kucukoduk, Sukru] Ondokuz Mayis Univ, Sch Med, Neonatal Unit, Samsun, Turkey -- [Sirmatel, Fatma -- Ustun, Cemal -- Baysal, Abant Izzet] Univ Hosp, Infect Dis & Clin Microbiol, Bolu, Turkey -- [Sener, Alper -- Otkun, Metin] Onsekiz Mart Univ Canakkale, Canakkale, Turkey -- [Tuna, Nazan] Sakarya Univ, Fac Med, Sakarya, Turkey -- [Akan, OTzay Arikan -- Tulunay, Melek -- Oral, Mehmet -- Unal, Necmettin] Ankara Univ, Ibni Sina Hosp, Sch Med, TR-06100 Ankara, Turkey -- [Turgut, Huseyin -- Sacar, Suzan -- Sungurtekin, Hulya -- Ugurcan, Dogac] Pamukkale Univ, Denizli, Turkey -- [Demiroz, A. Pekcan -- Yetkin, M. Arzu -- Bulut, Cemal -- Erdinc, F. Sebnem -- Hatipoglu, Cigdem Ataman] Ankara Numune Training & Res Hosp, Ankara, Turkey -- [Kendirli, Tanil -- Ince, Erdal -- Ciftci, Ergin -- Odek, Caglar -- Yaman, Ayhan -- Karbuz, Adem -- Aldemir, Bilge] Ankara Univ, Sch Med, Dept Paediat Crit Care Med, TR-06100 Ankara, Turkey -- [Alp, Emine -- Kilic, Aysegul Ulu] Erciyes Univ, Fac Med, Kayseri, Turkey -- [Uzun, Cengiz] German Hosp, Istanbul, Turkey -- [Ulusoy, Sercan -- Arda, Bilgin -- Bacakoglu, Feza] Ege Univ, Fac Med, Izmir, Turkey -- [Arman, Dilek -- Hizel, Kenan] Gazi Univ, Sch Med, Ankara, Turkey -- [Cengiz, Mustafa -- Yilmaz, Leyla] Harran Univ, Fac Med, Sanliurfa, Turkey, Ciftci, Ergin -- 0000-0002-4955-160X, Leblebicioglu, Hakan -- 0000-0002-6033-8543, Horoz, Ozden Ozgur -- 0000-0001-7590-650X, Erben, Nurettin -- 0000-0003-0373-0132, Yalcin, Ata Nevzat -- 0000-0002-7243-7354, UNAL, SERHAT -- 0000-0003-1184-4711, MERİÇ KOÇ, MELİHA, Çukurova Üniversitesi, OMÜ, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Sırmatel, Fatma, and Ege Üniversitesi

Subjects
Male, Pediatrics, healthcare associated infection, Turkey, Antibiotic resistance, medicine.medical_treatment, health care facilities, manpower, and services, central venous catheter, Network, intensive care unit, preschool child, Turkey (republic), law.invention, Cohort Studies, Nosocomial infection, law, newborn, device infection, Prevalence, Infection control, Prospective Studies, Prospective cohort study, Child, intensive care, catheter infection, Cross Infection, Urinary tract infection, adult, Ventilator-associated pneumonia, Pneumonia, Ventilator-Associated, General Medicine, cohort analysis, INICC, Intensive care unit, infection control, Device-associated infection, Infectious Diseases, female, Equipment and Supplies, Child, Preschool, disease surveillance, Central venous catheter, devices, Cohort study, prospective study, Microbiology (medical), medicine.medical_specialty, Adolescent, Catheter-associated urinary tract infection, infection rate, Bloodstream infection, Article, critically ill patient, length of stay, Intensive care, medicine, Humans, Hospital infection, human, Healthcare-associated infection, urinary catheter, business.industry, Research, Infant, Newborn, Infant, International Nosocomial Infection Consortium, mechanical ventilator, medicine.disease, Nosocomial infection control, major clinical study, mortality, Catheter-Related Infections, Emergency medicine, ventilator associated pneumonia, Central line-associated bloodstream infections, business
Abstract

WOS: 000346433300001, PubMed ID: 25403704, Background: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. Methods: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods. Results: We collected prospective data from 94,498 ICU patients for 647,316 bed days. Pooled DA-HAI rates for adult and paediatric ICUs were 11.1 central line-associated bloodstream infections (CLABSIs) per 1000 central line (CL)-days, 21.4 ventilator-associated pneumonias (VAPs) per 1000 mechanical ventilator (MV)-days and 7.5 catheter-associated urinary tract infections (CAUTIs) per 1000 urinary catheter-days. Pooled DA-HAI rates for NICUs were 30 CLABSIs per 1000 CL-days, and 15.8 VAPs per 1000 MV-days. Extra length of stay (LOS) in adult and paediatric ICUs was 19.4 for CLABSI, 8.7 for VAP and 10.1 for CAUTI. Extra LOS in NICUs was 13.1 for patients with CLABSI and 16.2 for patients with VAP. Extra crude mortality was 12% for CLABSI, 19.4% for VAP and 10.5% for CAUTI in ICUs, and 15.4% for CLABSI and 10.5% for VAP in NICUs. Pooled device use (DU) ratios for adult and paediatric ICUs were 0.54 for MV, 0.65 for CL and 0.88 for UC, and 0.12 for MV, and 0.09 for CL in NICUs. The CLABSI rate was 8.5 per 1,000 CL days in the Medical Surgical ICUs included in this study, which is higher than the INICC report rate of 4.9, and more than eight times higher than the NHSN rate of 0.9. Similarly, the VAP and CAUTI rates were higher compared with U. S. NHSN (22.3 vs. 1.1 for VAP; 7.9 vs. 1.2 for CAUTI) and with the INICC report (22.3 vs. 16.5 in VAP; 7.9 vs. 5.3 in CAUTI). Conclusions: DA-HAI rates and DU ratios in our ICUs were higher than those reported in the INICC global report and in the US NHSN report., Foundation to Fight against Nosocomial Infections, The funding for the activities carried out at INICC head quarters were provided by the corresponding author, Victor D. Rosenthal, and Foundation to Fight against Nosocomial Infections.

Published
2014

15. Erysipelothrix rhusiopathiae pneumonia in an immunocompetent patient

Author

Meliha Meric, Sema Keceli Ozcan, and MERİÇ KOÇ, MELİHA

Subjects
Microbiology (medical), Adult, Male, Erysipeloid, Erysipelothrix rhusiopathiae, Microbiology, Erysipelothrix Infections, medicine, Pneumonia, Bacterial, Animals, Humans, Cutaneous infections, medicine.diagnostic_test, biology, business.industry, Respiratory disease, Sputum, General Medicine, medicine.disease, biology.organism_classification, respiratory tract diseases, Pneumonia, Bronchoalveolar lavage, Lung disease, Immunology, Erysipelothrix, medicine.symptom, business, Bronchoalveolar Lavage Fluid
Abstract

Erysipelothrix rhusiopathiae is a Gram-positive bacillus that causes infections primarily in animals. In humans, this bacterium usually causes localized cutaneous infections called erysipeloid. Here we report a case of pneumonia with isolation of E. rhusiopathiae from bronchoalveolar lavage and sputum. To our knowledge, this is the first report of a pneumonia case caused by E. rhusiopathiae confirmed by culture.

Published
2011

16. Effectivity of Daptomycin therapy in patients with febrile neutropenia

Author

Pinar Tarkun, M. Meric Koc, Aynur Aynioglu, and MERİÇ KOÇ, MELİHA

Subjects
Microbiology (medical), medicine.medical_specialty, business.industry, General Medicine, medicine.disease, lcsh:Infectious and parasitic diseases, Koc M., Aynioglu A., TARKUN P., -Effectivity of Daptomycin therapy in patients with febrile neutropenia-, INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, cilt.21, ss.198, 2014, Infectious Diseases, Internal medicine, medicine, lcsh:RC109-216, In patient, Daptomycin, business, Febrile neutropenia, medicine.drug
Published
2014

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