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Stafne cyst, named after Edward Stafne, was first described in 1942 when he noticed asymptomatic radiolucent cavities in intraoral radiographs of 35 different patients. It is usually a well-defined, round, ovoid or occasionally lobulated radiolucency of size 1–3 cm typically located in the submandibular gland fossa. In this paper, we present two cases of Stafne cyst, one with an unusual presentation having trapezoid-shaped radiolucency with scalloped margin involving the inferior border of the mandible and another with the usual presentation. In both the cases, diagnosis was based on clinical and radiological features alone without any surgical exploration. With the condition remaining static throughout the follow-up period, it is proven that noninvasive diagnostic radiography such as computed tomography scan with three-dimensional reconstruction and cone beam computed tomography can be very helpful for the definite diagnosis of Stafne cyst, rather than invasive procedures.

Langerhans cell histiocytosis (LCH) is characterized histologically by a monoclonal proliferation of large mononuclear cells accompanied by a prominent eosinophil infiltrate. The pathogenesis of LCH is unknown. Hand–Schuller–Christian (HSC) disease is a rare proliferative disorder in which pathological Langerhans cells (LCs) accumulate in various organs. The clinical manifestations arise as a result of accumulation and infiltration of the Langerhans cells in organs and tissues. HSC is characterized by a classic triad of exophthalmos, diabetes insipidus, and lytic lesions in the skull. It is usually manifested in children but can also affect adults. Here, we present a case of HSC disease in a 12-year-old boy with oral manifestations.