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Big data analytics applications are increasingly deployed on cloud computing infrastructures, and it is still a big challenge to pick the optimal cloud configurations in a cost-effective way. In this paper, we address this problem with a high accuracy and a low overhead. We propose Apollo, a data-driven approach that can rapidly pick the optimal cloud configurations by reusing data from similar workloads. We first classify 12 typical workloads in BigDataBench by characterizing pairwise correlations in our offline benchmarks. When a new workload comes, we run it with several small datasets to rank its key characteristics and get its similar workloads. Based on the rank, we then limit the search space of cloud configurations through a classification mechanism. At last, we leverage a hierarchical regression model to measure which cluster is more suitable and use a local search strategy to pick the optimal cloud configurations in a few extra tests. Our evaluation on 12 typical workloads in HiBench shows that compared with state-of-the-art approaches, Apollo can improve up to 30% search accuracy, while reducing as much as 50% overhead for picking the optimal cloud configurations.

The synergetic development level of port and city is an important index to measure the radiation effect of the port. Through systematic analysis and study at the development level of port-city systems in the Chengdu-Chongqing Economic Circle, this paper constructed a synergistics-based synergy degree model and proposed an index system of synergy degree measurement for a port-city complex system based on a coupling coordination degree model. Results show that the ports and cities in the Chengdu-Chongqing Economic Circle are still far from high-level synergetic development. In general, the comprehensive synergetic development level of the ports and cities are rising, in which Chongqing ranks the top and is still in a rising trend. The comprehensive development level of Luzhou and Yibin is also on the rise, but the gap between them and Chongqing is becoming bigger. The synergetic development level of port and city is an important index to measure the radiation effect of port and constructs a synergistics-based synergy degree model for a complex system and proposed an indicator system of synergy degree measurement for a port-city complex system based on a coupling coordination degree model from the perspective of systematics.

Background Sarcoidosis is a multi-system, idiopathic, inflammatory disorder that affects the lungs in over 90% of patients. The incidence of bone lesions in sarcoidosis is only 1-13%. Case report This study describes a 60-year-old woman with a previous history of thyroid cancer, and a more recent diagnosis of lung cancer with suspicious metastatic lesions, which were confirmed to be sarcoidosis. Conclusion This case suggests that pulmonary neoplasms and pulmonary sarcoidosis can coexist and be easily confused. When lung cancer is accompanied by symmetric hilar lymph node enlargement and multiple lung nodules, sarcoidosis should be considered in addition to metastasis, and a biopsy should be performed for confirmation.

To determine the prevalence of bladder and bowel dysfunction (BBD) and its relationship with delayed elimination communication (EC) in children. A cross-sectional study was carried out in kindergartens and primary schools in mainland China. A total of 10,166 children ranging from 4 to 10 years old were included. A total of 10,166 valid questionnaires were collected, and 409 children were diagnosed with BBD. The overall prevalence was 4.02% (409/10,166) and decreased with age, from 6.19% at age 4 to 1.96% at age 10. With the prolonged use of disposable diapers (DDs), the commencement of usage of EC in a child was significantly put off or delayed by parents, and the prevalence of BBD amongst these children increased (P

Ethnopharmacological relevance Jianpi Yangzheng Xiaozheng Decoction (JPYZXZ) is an empirical compound prescription based on the theory of traditional Chinese medicine. JPYZXZ, which is “Qi-invigorating, spleen-strengthening and stasis-removing,” can improve the quality of life of gastric cancer patients and prolong their survival; however, the exact mechanism underlying the antitumor effects of this compound is still not clear. Aim of the study The aim of this study is to clearly define the effect of JPYZXZ and its components, Jianpi Yangzheng Decoction (JPYZ) and Xiao Zheng San Jie Decoction (XZSJ), on inhibiting the progression of gastric cancer. Materials and methods The effect of JPYZXZ and its components on the motility of gastric cancer MGC-803 cells was measured by MTT, adhesion, transwell assays and wound-healing assays. JPYZXZ, JPYZ and XZSJ were administered to 615 mice with gastric cancer xenografts, and their effect on the inhibition of subcutaneous transplantation was analyzed. THP-1 monocyte cells were used to establish tumor-associated macrophage (TAM) models. The polarized state of the TAMs was detected by Flow Cytometry, ELISA and Immunohistochemistry. The mRNA and protein expression of tumor epithelial-mesenchymal transition (EMT) and TAM-related genes was determined by Real-time PCR and Western Blot, respectively. Results We determined that both JPYZXZ and its components inhibited the progress of gastric cancer in vitro, and JPYZXZ was clearly more effective than JPYZ or XZSJ. The in vivo results demonstrated that the JPYZXZ and XZSJ group exhibited a significant decrease in the tumor weight compared to the control group. Further analysis indicated that JPYZXZ was more active than JPYZ or XZSJ in inhibiting the gastric cancer EMT transformation both in vivo and in vitro. However, JPYZ was more effective compared with JPYZXZ for inducing the phenotypic change in macrophages from M2 to M1. Conclusions Our results demonstrate that both JPYZXZ and its components prevent the progress of gastric cancer. JPYZXZ inhibits the gastric cancer EMT more effectively than JPYZ and XZSJ, but JPYZ primarily works to regulate the phenotypic change in macrophages from M2 to M1.

In this paper, the dynamic loading tests of sandstone after heat treatment at 25-800?C are carried out by using the split Hopkinson pressure bar test system. Combined with the theory of energy dissipation, the dynamic fracture and energy consumption characteristics of coal-series sandstone are systematically studied. The test results illustrate that the dynamic fracture and energy consumption characteristics of sandstone are mainly related to the changes of internal moisture and cementing materials.

Operating at low load conditions may cause strong and non-synchronous unsteadiness and a high blade dynamic loading for the last stage blades (LSB). Full annulus models should be used to investigate the circumferential asymmetric flow unsteadiness and blade vibrations. Currently, although full annulus models have been applied to numerical aerodynamic studies, to authors’ knowledge, there is still no research including the full annulus in structural analysis due to the high computational cost. In this paper, an unsteady aerodynamic and structural coupled analysis method for an industrial steam turbine LSB using full annulus model under low load conditions is presented. To conduct finite element method (FEM) with limited computational resources, a new structural analysis procedure is proposed to calculate the dynamic stress. The aerodynamic analysis is conducted in both steady and unsteady computational fluid dynamics (CFD) calculations. The tip pressure ratio in the steady state calculations is used to predict the aerodynamic loading intensity. The unsteady results indicate typical flow characteristics under low load conditions, which show a big separation region behind the last rotor and tip vortex between last stator and rotor. Unsteady aerodynamic loading is mapped onto the blade surface as the excitation force. The structural analysis is performed to investigate the characteristics of blade vibrations and stress distributions of the full annulus LSB. Repeating the method, a reasonable characteristics curve of vibration stress against flow rates for LSB is calculated.

A zero bias Schottky barrier diode with 3.5THz cut-off frequency and 0.16eV barrier height based on the InGaAs-Ti contact is designed and fabricated with a new T-gate anode, anisotropic wet mesa etch and BCB protection process. By using this SBD, a high-sensitivity detector working at W band frequency is proposed, and the measured responsivity is over 4000V/W at 75~110GHz.

In consideration of the influence of target moving, components rotarying and structure deformation on the precision of electromagnetic scattering modeling A an exact moving target’s RCS modeling method based on the measured data was proposed in this paper. Firstly, using laser scanning method to build the precise geometric model of the real target; Secondly, extracting the parameters of the target motion characteristics in the actual flight, and taking the parameters to modify the model; Finally developing integration software to calculate the electromagnetic scattering and verify the result with the measured data.

In order to study the mechanical characteristics including deformation, displacement and stress distribution of surrounding rock during the process of filling mining with different filling rate, according to the geological and mining conditions of the 12307 working face in some coal mine, the analyses of simulation were synthetically applied. The results show that the deformation and failure of overburden rock is closely related to the filling rate, when the filling rate is low, the fractures are extensive, longitudinal and transverse fractures are staggered, the vertical displacement of rock strata is differentiated obviously,while filling rate is high, the fractures appeared only in low strata, the rock strata displacement main occurs near the immediate roof, the strata displacement curves in the stable subsidence area are almost together, the rock presents the overall bending deformation, from the roof to the surface layers are whole movement characteristics. There is a power function between the influence distance and the filling rate, the concentrated stress decreases linearly with the increase of filling rate.The filling rate is an important factor to control the strata movement and surface deformation, the results of the study are of great significance to guide practice in filling mining.

We present a novel in vitro model in which to investigate the efficacy of experimental drugs for the promotion of axon regeneration in the central nervous system. We co-cultured rat hippocampal neurons and cerebral cortical oligodendrocytes, and tested the co-culture system using a Nogo-66 receptor antagonist peptide (NEP1-40), which promotes axonal growth. Primary cultured oligodendrocytes suppressed axonal growth in the rat hippocampus, but NEP1-40 stimulated axonal growth in the co-culture system. Our results confirm the validity of the neuron-oligodendrocyte co-culture system as an assay for the evaluation of drugs for axon regeneration in the central nervous system.

Based on the prototype of No. 2307 filling working face in Yuyang mine, using the method of similar simulation combined with numerical simulation, the geological mechanics model is established to simulate and analyze the mechanics evolution law and the deformation and movement process of the surrounding rock and the surface during the filling mining. Research shows that backfilling can effectively control surrounding rock failure and the surface deformation, and the roof doesn’t collapse, but the bed separated fissures appear, and the maximum stagnation lags the working face by 58.5m; in the mining, surrounding rock stress releases and roof stretches, and the stress concentration appears in the front and end of the goaf, which is 1.47~1.78 times larger than that before mining, and the periodic weighting of filling working face is not obvious; the subsidence value is 212.7 mm after excavation, with the factor 0.06, and the ground level deformation and slope deformation shape are similar to the curve shape of roof caving control method with small values. The results have important theoretical guiding significance for controlling surface movement deformation in actual filling mining.

In the process of open-pit mine stripping,the surface and slop that influenced by open-pit mining stripping, rock mass structure and lithology, blasting vibration, slope angle, groundwater and precipitation start to move and deform,which threatens the safe use of industrial and civil buildings adjacent to the open pit mining .In this paper, through the establishment of increasing the momentum of adaptive BP neural network,with the aid of existing sample data,we carried out on the network training, testing, and compared with the target, its precision is higher.The result showed that network is effective and reliable,and the trained network is applied to the observation point prediction,so we get the value of its settlement deformation in 2013.The method is expected to have the important meaning on the multi-factor coupling surface subsidence .

We designed radiation effect experimental system including current measurement section and functional test section for Xilinx Zynq-7010 System on chip (SoC) and performed the Total Ionizing Dose (TID) experiment irradiated by Co60 γ-source on the chip. At the dose rate of 0.04 Gy(Si)/s, the total dose of 1.69 kGy(Si), the current value in the experiment increased first and then decreased. The test board got functional interruption at the gamma dose of 1.69 kGy(Si). The function of the board normalized after room temperature annealing and 70°C high temperature annealing except that the current value decreased by 28% compared to the current before irradiation. The mechanisms for the first TID test results on Xilinx SoC were deduced and discussed.

In this paper, the problems of motor drive for nozzle extrusion mechanism in FDM 3D printer were analyzed. A method of controlling stepper motor speed for execute G code file was proposed, then the principle of the method is analyzed and deduced. The method was emulated in MATLAB, compared and analyzed with actual data and the original T shape acceleration and deceleration algorithm.

For environment and user needs easy-to-change issues in the Web application system application, the ideology of flexible software and Web interface design combining in the paper, we proposed a dynamic reconfiguration capability flexible component-based Web user interface model. The model displays the description of component style templates and adapts to the structural changes of business data component rules stored in the XML documents and relational databases, so as to solve the adaptability and reusability of Web user interface. Finally, a flexible Web user interface of the table data display function to illustrate the effectiveness and availability of the model.

A new target recognition method for SAR images is proposed.An advanced denoising method named BM3Dis introduced for the speckle noise suppression at the first time.BM3Dfilter combines advantages in space-domain denoising with those in transform-domain denoising,which leads to better performance.For the feature vector extraction step,Hu moments,which describe the target's cursory information,and Zernike moments,which describe target's fine information,are fused to construct the combination moments.In this way,the combination moments can express the target more comprehensively and precisely.In our experiment the moments are extracted from SAR images and used to train SVM classifier,and the experiment results indicate that the proposed method can obtain a recognition rate of 98.90%,which outperforms other SAR recognition methods.

This paper studies on the ultimate failure modes and bearing capacity of high intake tower under the action of seismic load based on nonlinear concrete model. By monitoring the way of crack development and failure process of the tower to study failure mode under the action of various seismic wave, we can conclud that the regional distributions of the structural crack of tower body vary with the duration of an earthquake. In the early period of earthquake, the crack has little effect on the whole structure. After duration of the earthquake, the structure forms penetrable cracks. By studying the cracks development and distribution on the structure of tower body under the action of various seismic waves, we know the failure process and failure mode of high intake tower. The conclusions provide evidence for engineering design and seismic analysis of pertinent engineering.

The regional ecological risk assessment of water resources has spatial, nonlinear and stochastic characteristics. GIS technology can handle large volumes of spatial information, conduct spatial analysis and spatial data management operations. It visually displays the distribution trend of environmental factors and the relationship between topology and regional water ecological risk pattern. This paper presents the five stages of the application of GIS in the regional ecological assessment of water resources and establishes a GIS water environmental risk information database. A hierarchy water resources risk assessment index system has been set up using the AHP method. The composite index method is used to estimate the size of ecological risk. The water risk value is divided into five levels which are the low-risk areas, lower-risk areas, medium-risk areas, higher risk areas and high-risk areas, respectively. For example, through the spherical model fitting and assembly analysis of GIS, the variations and divisions of water risk and their influencing factors in the Shaanxi Province, China, can be better described and analyzed. Therefore, GIS can be employed as a better tool to reflect the spatial distribution of water environmental quality. Accordingly, it can be used to quantitatively study the water resource risk, and to reflect the spatial variation of the water resource risk. Moreover, early warning of water resources utilization can be given, thus providing a basis to improve and enhance the water resources risk management and scientific decision-making.

In order to solve the coupling of rotor current of d axis and q axis, a new kind of control scheme for double-fed induction machine (DFIM) speed regulation system is proposed based on the theory of auto disturbance rejection controller (ADRC). The ADRC is composed of three parts: tracking-differentiator (TD), extended state observer (ESO) and nonlinear state feedback controller (NSFC). In the ADRC scheme, the coupling of rotor current is regarded as the inner disturbance of DFIM, inputting this disturbance to the input port of the speed regulation system by the feedforward compensation, the speed regulation system can change to the simple integral series connection system or simple linear system. This controller can realize decoupling of rotor current of d axis and q axis, obtaining a good speed tracking performance with small overshoot and fast setting time. Simulation results indicate the rationality and validity of the ADRC.

With the water tourism developed, making the development of water landscape rising rapidly. How to ensure the safety of hydraulic engineering technology under normal circumstances, and protect the ecological environment, play tourism economic benefits are an important problem in landscape design. Under the premise of following the principle of water conservancy landscape planning and design, applying AHP to research Xiya ditch waterfall landscape and optimize design program, then set up the preferred plan from ecological effect, waterfalls and technological factors three aspects of evaluation index. This provides theory basis for model test and engineering implementation in Xiya ditch waterfall landscape. In recent years, water conservancy projects relying on water industry form a large number of humanities landscape, natural landscape. The development of water tourism, gradually achieved a certain economic, social and environmental benefits. Giving full play to the comprehensive benefits of water conservancy projects, Ministry of Water Resources has granted water tourism as three major elements in water economy with water supply, power generation.

Application of doubly-fed variable speed system in motor-generator station is a new field in marine. This paper introduced the theory of doubly-fed variable speed and the design of doubly-fed system, adopted stator flux orientation vector control in induction motor by rotor current control with inverter. A kind of simple and fast starting device was designed, thus the power demand of inverter was reduced greatly. Experiment results showed that doubly-fed induction machine was good for speed adjusting and transient speed change rate was smaller than 1%.

A direct temperature control method for electric heating dryers was proposed in order to obtain satisfactory control effect. The controller of analog compound orthogonal neural network used a direct adaptive control method. Simulation results show that this controller has higher speed performance and smaller overshoot than a PID controller. It is suitable for the control of uncertain objects and provides a novel approach for the control of uncertain systems.

The paper explores the question of the Chinese language epic, a topic frequently discussed in academic circles throughout the 20th century. Over the past century, many academics of an older generation have put forward ideas for resolving this issue, which arose from the perspective of the origins of Western literature. But careful examination indicates that all the hypotheses and explanations do not faithfully or fully adhere to the facts themselves. This academic affair arose in the course of eastward spread of Western influences when numerous scholars tried to explain the origins of Chinese literature by transplanting to Chinese soil a model of the origins of Western literature. The author doubts the logic of taking such a model as a universal interpretative framework for the historical development of literature or using epic poetry to explain the sources of Chinese literature. Underlying the fact that their academic consciousness was not based on a profound understanding of the facts and materials was a blind and unreflective pursuit of Western discourse; there are lessons to be learned from this.

The neonatal period is critical in bladder development, encompassing the transition from foetal bladder contractions to voluntary infant urination. The aim of this study was to investigate different voiding parameters between male and female newborn infants.We studied 102 healthy, single birth newborn infants - 54 preterm and 48 full-term - without lower urinary tract diseases, hospitalised in the neonatal intensive care unit from March 2011 to March 2012. Free voiding was observed from 9 a.m. to 9 p.m., and the free voiding parameters and fluid intake were recorded and compared between male and female newborn infants using the Student's t-test and chi-square test.Male preterm newborns demonstrated larger mean postvoid residual volumes and lower bladder emptying rates than female preterm newborns (p 0.05), and male full-term newborns had lower bladder emptying rates than female full-term newborns (p 0.05). The bladder emptying rates of newborns defecating simultaneously with voiding were not statistically different between males and females of the same gestational age (p 0.05).Male newborns were more likely to have larger postvoid residual volumes than females, and defecating simultaneously with voiding may promote bladder emptying in male newborns.

Through investigation on Qingdao university teacher college 100 web courses and its authors, we found web courses based on THEOL platform have series of questions during construction and operation process. Such as: simplicity of platform needs to be improved, partial course projects need to be adjusted, teachers' ideas need to be changed, etc. Therefore, we must adopt some effective measures such as policy incentives, conception change, co-construction courses and sharing high quality resources and so on.

Through investigation on Qingdao university teacher college 100 web courses and its users, we found web courses based on THEOL platform have series of questions in use process. Such as: platform and resource needs to be improved, Students' learning stays in the shallow learning state, Emotion exchange loss, etc. Therefore, we must adopt some effective measures such as Strengthening software and hardware construction, Lead and manage learners, Improve leaners' learning ability, Meet learners' emotional needs and so on.

Cooperative work, if it is by a team of engineers, or by a group of experts, requires coordination by sharing common knowledge. We focus on knowledge exchange game as the methodology of sharing knowledge. Knowledge exchange processes are formulated as knowledge exchanging games among selfish agents. Each agent has idiosyncratic utility function defined over his private knowledge and common knowledge. Each agent exchanges his knowledge with others in order to improve his own utility. In this paper, we focus on heterogeneity of agents. Agent decide whether trade or not in terms of cost and value of new knowledge. The way to decide is different from each agent. We investigate what characteristics of an organization promote knowledge exchanging or discourage sharing common knowledge.

The inter-organization comprises a new type of environment around which firms organize themselves so as to reach a common objective. The structure and attributes of inter-organizational network can possibly account for the performance of knowledge transfer. This paper describes and analyzes some of key network factors, and presents a conceptual research framework.

The imbalance of dataset will directly affect the precision of classifier. PC4.5, an improved C4.5 algorithm is proposed. The experiments in MIT dataset indicate that PC4.5 is effective on imbalanced dataset and the scale of the decision tree could be reduced.

As a novel personal area network (PAN) technology, The Bluetooth system provides a point-to-point connection or a point-to-multipoint connection. This paper address the networking of Bluetooth system, especially analyzes the needs for frequency hopping and the lack of a central controller in ad hoc radio networks.

Bluetooth is a novel technology of short-range wireless communications. Bluetooth is robust to interference. The detailed modulation and coding technique which led to the robustness is described and analyzed in this paper.