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1,064 results on '"Last A"'

1. What is ...: THE BEST SCENT OF THE LAST 12 MONTHS? Employees at aroma compounds manufacturer Carvansons round-up their pick of the best new perfume launches

Author: Last, Vicki
Subjects: Jean Paul Gaultier, Perfumes industry, Perfumes, Toiletries industry, Business, Pharmaceuticals and cosmetics industries, Business, international
Abstract: Every year Carvansons does a round-up of the best perfumes of the year. For this article, we decided to take a glance at some of our own in-house creations and [...]
Published: 2024

2. Deepening Sustainable Value Creation in Market-led Poverty Alleviation through a Demand and Supply Integration Framework: Significance to Tourism.

Author: Last Mazambani and Emmanuel Mutambara
Subjects: Market-led poverty alleviation, sustainable value creation, low-income market, bottom of the pyramid, corporate profitability, demand and supply integration, community tourism, Hospitality industry. Hotels, clubs, restaurants, etc. Food service, TX901-946.5, Business, HF5001-6182
Abstract: There has been global interest in corporate-led poverty alleviation initiatives. However, failure to simultaneously achieve profitability and poverty alleviation threatens the sustainability of the initiatives. The idea is further exacerbated by business’ continued use of traditional business practices which perpetuate the exclusion of poor people from markets. Based on literature review, this article presents a demand and supply integration conceptual framework attendant to both the demand-side and supplyside of the business as a sustainable business practice that can elevate the simultaneous pursuit of profit and poverty alleviation. The study concludes that sustainable business-led poverty alleviation is achievable when low-income customer perspectives are captured in the business solutions aimed at addressing the foundational causes of poverty. Attending to demand creation with corresponding supply capabilities in serving poor people places poverty alleviation as a core part of a sustainable corporate strategy capable of simultaneously reducing poverty while generating profits. While the presented conceptual framework is applicable to many industries, it can be impactful in labour intensive sectors like community tourism. Tourism has the power to use local tools and resources that can increase opportunities and agency for poor communities. Corporates will benefit from creating a source and market for their products.
Published: 2018

3. Attractions of Cape Town to African Francophone Students.

Author: Last Mazambani, Tariro Juliet Rushwaya, and Emmanuel Mutambara
Subjects: Cape Town, Educational Tourism, African Francophone Students, Intra-Africa Tourism, South Africa, Hospitality industry. Hotels, clubs, restaurants, etc. Food service, TX901-946.5, Business, HF5001-6182
Abstract: This study set out to find the attractions of Cape Town as an educational destination for African francophone students using a qualitative interview-based research methodology. Francophone students migrate to Cape Town to firstly learn the English language and then seek tertiary education of global repute. The natural environment, lifestyle, personal safety and generally tolerant local people are added attractions. Incidences of racism, xenophobic attacks, high rentals and college fees negate students' experiences in the city and leave abad tsate in the mouth. Insightful recommendations are drawn to address the real needs of African francophone students which generally appear to be misunderstood and unaddressed by formal tertiary learning institutions and other interested organizations.
Published: 2018

4. Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2

Author: Andreas Greinacher, Linda Schoenborn, Jo-Ann I. Sheppard, Edelgard Lindhoff-Last, Joerg Herold, Michael Piorkowski, and Theodore E. Warkentin
Subjects: Vaccination, 2019-20 coronavirus outbreak, Immune system, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicine, Hematology, business, Virology
Published: 2021

5. Clinical and cardiac magnetic resonance findings in post-COVID patients referred for suspected myocarditis

Author: Marco Schmidt, Edelgard Lindhoff-Last, Rajendra H. Mehta, Philipp Breitbart, Axel Schmermund, Alexander Koch, Annett Magedanz, Holger Eggebrecht, and Thomas Voigtländer
Subjects: Adult, Male, medicine.medical_specialty, Myocarditis, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Disease, Chest pain, Ventricular Function, Left, Electrocardiography, Fibrosis, Internal medicine, medicine, Humans, Cardiac imaging, Original Paper, Ejection fraction, business.industry, MR-tomography, COVID-19, Heart, Stroke Volume, General Medicine, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Myocardial inflammation, Echocardiography, Cardiology, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Cardiac magnetic resonance
Abstract: Objectives We assessed possible myocardial involvement in previously cardiac healthy post-COVID patients referred for persisting symptoms with suspected myocarditis. Background Prior studies suggested myocardial inflammation in patients with coronavirus-induced disease 2019 (COVID-19). However, the prevalence of cardiac involvement among COVID patients varied between 1.4 and 78%. Methods A total of 56 post-COVID patients without previous heart diseases were included consecutively into this study. All patients had positive antibody titers against SARS-CoV-2. Patients were referred for persistent symptoms such as chest pain/discomfort, shortness of breath, or intolerance to activity. All patients underwent standardized cardiac assessment including electrocardiogram (ECG), cardiac biomarkers, echocardiography, and cardiac magnetic resonance (CMR). Results 56 Patients (46 ± 12 years, 54% females) presented 71 ± 66 days after their COVID-19 disease. In most patients, the course of COVID-19 was mild, with hospital treatment being necessary in five (9%). At presentation, patients most often reported persistent fatigue (75%), chest pain (71%), and shortness of breath (66%). Acute myocarditis was confirmed by T1/T2-weighed CMR and elevated NTpro-BNP levels in a single patient (2%). Left ventricular ejection fraction was 56% in this patient. Additional eight patients (14%) showed suspicious CMR findings, including myocardial edema without fibrosis (n = 3), or non-ischemic myocardial injury suggesting previous inflammation (n = 5). However, myocarditis could ultimately not be confirmed according to 2018 Lake Louise criteria; ECG, echo and lab findings were inconspicuous in all eight patients. Conclusions Among 56 post-COVID patients with persistent thoracic complaints final diagnosis of myocarditis could be confirmed in a single patient using CMR. Graphic abstract
Published: 2021

6. A simple approach to dynamic material balance for a dry-gas reservoir

Author: Kittiphong Jongkittinarukorn, Nick Last, Sarfaraz Ahmed Jokhio, Freddy Humberto Escobar, and Jirawat Chewaroungroaj
Subjects: business.industry, Dry gas, 02 engineering and technology, 010502 geochemistry & geophysics, Geotechnical Engineering and Engineering Geology, 01 natural sciences, Field (computer science), Numerical integration, chemistry.chemical_compound, General Energy, Material balance, 020401 chemical engineering, chemistry, Simple (abstract algebra), Offshore geotechnical engineering, Production (economics), 0204 chemical engineering, Process engineering, business, Reliability (statistics), 0105 earth and related environmental sciences
Abstract: The dynamic material balance methodology can be used to estimate gas initially-in-place using only production and PVT data. With this methodology, reservoir pressure is obtained without requiring the well to be shut in; it is therefore superior to the static material balance method since there is no loss of production. However, the technique requires iterative calculations and numerical integration of gas pseudotime and is quite complex to implement in practice. A simpler and equally accurate methodology is proposed in this study. It requires only production and PVT data and also does not rely on a shut-in pressure survey. In addition, it requires neither iterative calculations nor numerical integration of gas pseudotime. The results of the analysis include gas initially-in-place and gas productivity index, and can easily be extended to production forecasting. Gas initially-in-place is evaluated with a high degree of reliability. The methodology is successfully tested with two simulated cases and one field case, giving high-accuracy results.
Published: 2021

7. Customers’ perception of Service Quality and its impact on reputation in the Hospitality Industry.

Author: Tsietsi Mmutle and Last Shonhe
Subjects: Service quality, customer satisfaction, customer perception, reputation, Mmabatho Palms hotel, Hospitality industry. Hotels, clubs, restaurants, etc. Food service, TX901-946.5, Business, HF5001-6182
Abstract: Customer satisfaction and the management of their expectations are a strategic component to the sustainability of any organisation. It is argued that these two strategic components are the most important features that generate customer allegiance and desired retention. In the hospitality industry, hotels are attempting to obtain augmented customer satisfaction by concentrating on the quality of service they provide to guests. The objective of this paper was to examine the customers’ perception of service quality and its impact on a selected hotel’s reputation. A qualitative research method was used and data was collected using in-depth semi-structured interviews with both customers and employees as core stakeholders. The findings indicate that service quality has an impact on hotel reputation as poor service provision invariably leads to negative conversations and bad publicity concerning the hotel. It also emerged that the customers and service providers have more or less similar notions of what service quality entails. The hotel departments have mechanisms and strategies for meeting and exceeding customer satisfaction and especially of dealing with customer complaints and these are important when one desires organisational stability.
Published: 2017

8. Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

Author: Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Abdelaziz, Mohamed Abdelfattah, Bushra Abdelqader, David Abdo, Basir Abdul, Althaf Abdul Rasheed, Ajibode Abdulakeem, Rezan Abdul-Kadir, Amina Abdulle, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul Amna Abeer Ul Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmed Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andres Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Sara Adair, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Lisa Adams, Richard Adams, Tim Adams, Kirsty Adcock, Jemaimah Addai, Ade Adebiyi, Ken Adegoke, Vicki Adell, Debo Ademokun, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron-Thomas, Debbie Affleck, Dominic Affron, Carmel Afnan, Muhammad Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Penny Agent, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Humayun Ahmad, Mohammad Ahmad, Syed Ahmad, Asim Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Iram Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, Sophia Ahmed, Syed Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed, Sana Ahmer, Dhiraj Ail, Mark Ainsworth, Giulia Airoldi, Myriam Aissa, Lindianne Aitken, Bini Ajay, Francis Ajeneye, Abdulakeem Ajibode, Ayesha Ajmi, Tahir Akbar, Naim Akhtar, Nasim Akhtar, Nauman Akhtar, Suha Akili, Oludoyinsola Akindolie, Yinka Akinfenwa, Olugbenga Akinkugbe, Ibrahim Akinpelu, Olajide Akinwumiju, Olugbenro Aktinade, Ahmad Al Aaraj, Asma Al Balushi, Majd Al Dakhola, Aladdin Al Swaifi, Eslam Al-Abadi, Narendra Aladangady, Ayaz Alam, Sajid Alam, Abbas Al-Asadi, Karina Al-Asadi, Kyriaki Alatzoglou, Manaf Al-Bayati, Paul Albert, Lorraine Albon, Gemma Alcorn, Stephen Alcorn, Aggie Aldana, David Alderdice, Rayan Aldouri, Jonathan Aldridge, Nicolas Aldridge, Ana Alegria, Alison Alexander, John Alexander, Peter D G Alexander, Charlotte Alford, Julyan Al-Fori, Laith Alghazawi, Bahij Al-Hakim, Shams Al-Hity, Ali Ali, Asad Ali, Fawzia R Ali, Hoodo Ali, Jawad Ali, Mariam Ali, Mohammad Ali, Nayab Ali, Oudai Ali, Sabira Ali, Sakina Ali, Syed Ali, Abid Alina, Fine Aliyuda, Katrin Alizadeh, Maithem Al-Jibury, Saba Al-Juboori, Majid Al-Khalil, Moutaz Alkhusheh, Allameddine Allameddine, Fiona Allan, Rachel Allan, Alison Allanson, Robert Allcock, Beverley Allen, Eireann Allen, Jess Allen, Kerry Allen, Laura Allen, Louise Allen, Poppy Allen, Rebecca Allen, Sam Allen, Sharon Allen, Simon Allen, Kathryn Allison, Bethan Allman, Lynne Allsop, Hassan Al-Moasseb, Magda Al-Obaidi, Lina Alomari, Akram Al-Rabahi, Bahar Al-Ramadhani, Zayneb Al-Saadi, Inji Alshaer, Rustam Al-Shahi Salman, Warkaq Al-Shamkhani, Bashar Al-Sheklly, Sara Altaf, Mary Alvarez, Balaal Alyas, Maysaa Alzetani, Susan Amamou, Noor Amar, Sakkarai Ambalavanan, Sarah-Jayne Ambler, Robert Ambrogetti, Chris Ambrose, Amir Ameen, Kenneth Amenyah, Maria R Amezaga, Allison Amin, Amina Amin, Kanish Amin, Syed Amin, Tara Amin, Amjad Amjad, Neelma Amjad, Mariam Ammoun, Victoria Amosun, Khaled Amsha, Pugh Amy, Atul Anand, Rekha Anand, Samantha Anandappa, Julie Anderson, Kevin Anderson, Laura Anderson, Michelle Anderson, Nicola Anderson, Rachel Anderson, Rory Anderson, Wendy Anderson, Prematie Andreou, Angela Andrews, Antonette Andrews, Jill Andrews, Susan Andrews, Gregory Andrikopoulos, Kanayochukwu Aneke, Andrew Ang, Wan Wei Ang, Tammy Angel, Aramburo Angela, Paola Angelini, Lazarus Anguvaa, Oleg Anichtchik, Millicent Anim-Somuah, Krishnan Aniruddhan, Jessica Annett, Patrick J Anstey, Rebekah Anstey, Alpha Anthony, Aaron Anthony-Pillai, Philip Antill, Zhelyazkova Antonina, Varghese Anu, Muhammad Anwar, George Apostolides, Aristeidis Apostolopoulos, Sarah Appleby, Diane Appleyard, Maia Far Aquino, Bianca Araba, Samuel Aransiola, Mariana Araujo, Emily Arbon, Ann Archer, Denise Archer, Simon Archer, Christian Ardley, Ana-Maria Arias, Ryoki Arimoto, Charlotte Arkley, Charlotte Armah, Ilianna Armata, Adam Armitage, Ceri Armstrong, Maureen Armstrong, Sonia Armstrong, Sylvia Armstrong-Fisher, Philippa Armtrong, Heike Arndt, Clare Arnison-Newgass, David Arnold, Rachael Arnold, Sarah Arnott, Dhawal Arora, Kavan Arora, Pardeep Arora, Rishi Arora, Andrea Arroyo, Arslam Arter, Ayush Arya, Rita Arya, Denisa Asandei, Adeeba Asghar, Catherine Ashbrook-Raby, Glen Ashby, Helen Ashby, Jan Ashcroft, John Ashcroft, Samuel Ashcroft, Deborah Asher, Ayesha Ashfaq, Ben Ashford, Suhail Ashgar, Abdul Ashish, Sally Ashman-Flavell, Sundar Ashok, Abd-El-Aziz Ashour, Muhammad Z Ashraf, Saima Ashraf, Mohammad B Ashraq, Deborah Ashton, Susan Ashton, Andrew Ashworth, Rebecca Ashworth, Arshia Aslam, Harshini Asogan, Abigail Asquith, Atif Asrar, Omar Assaf, Raine Astin-Chamberlain, Richard Athay-Hunt, Deborah Athorne, Billie Atkins, Christopher Atkins, Stacey Atkins, John Atkinson, Vicki Atkinson, Brygitta Atraskiewicz, Claire Atterbury, Abdul Ahmad Attia, Rita Atugonza, Paula Aubrey, Avinash Aujayeb, Aye Chan Thar Aung, Hnin Aung, Kyaw Thu Aung, Ni Aung, Yin Aung, Zaw Myo Aung, Emily Austin, Karen Austin, Abdusshakur Auwal, Miriam Avery, Joanne Avis, Georgina Aviss, Cristina Avram, Paula Avram, Gabriel Awadzi, Atia Awan, Aszad Aya, Eman Ayaz, Amanda Ayers, Jawwad Azam, Mohammed Azharuddin, Ghazala Aziz, N Aziz, Ali Azkoul, Ashaari Azman Shah, Giada Azzopardi, Hocine Azzoug, Fiyinfoluwa Babatunde, Melvin Babi, Babiker Babiker, Gayna Babington, Matthew Babirecki, Marta Babores, Adetona O Babs-Osibodu, Sammy Bacciarelli, Roudi Bachar, Gina Bacon, Jenny Bacon, Bibi Badal, Gurpreet R Badhan, Shreya Badhrinarayanan, Joseph P Bae, Sibel Bafekr Mishamandani, Alice Baggaley, Amy Baggott, Graham Bagley, Dinesh Bagmane, Lynsey Bagshaw, Kasra Bahadori, James Bailey, Katie Bailey, Lindsey Bailey, Liz Bailey, Morgan Bailey, Pippa Bailey, Sarah Bailey, Stephen Bailey, Hamish Baillie, J Kenneth Baillie, Jennifer Bain, Sanchia Baines, Vikram Bains, Aimi Baird, David Baird, Susan Baird, Tracy Baird, Yolanda Baird, Aiysha Bajandouh, Charles Baker, Emma Baker, Evelyn Baker, Johanne Baker, Josephine Baker, Kenneth Baker, Rebecca Baker, Terri-Anne Baker, Victoria Baker, Hugh Bakere, Nawar Bakerly, Michelle Baker-Moffatt, Nauman Bakhtiar, Panos Bakoulas, Julie Balaam, Niranjan Balachandran, Andrea Balan, Theodosios Balaskas, Madhu Balasubramaniam, Alison Balcombe, Alexander Baldwin, Ashley Baldwin, Caron Baldwin, Danielle Baldwin, Rebekah Baldwin-Jones, James Balfour, Gagan Bali, Sonya Balkee, Ceri Ball, Kasia Ballard, Amy Ballinger, Ismael Balluz, Craig Balmforth, Emese Balogh, Amir Baluwala, Gabby Bambridge, Alasdair Bamford, Amy Bamford, Peter Bamford, Adefunke Bamgboye, Elizabeth Bancroft, Hollie Bancroft, Tanya Bancroft, Joyce Banda, Krishna Bandaru, Srini Bandi, Nageswar Bandla, Somaditya Bandyopadhyam, Amit Banerjee, Millie Banerjee, Ritwik Banerjee, Harrison Banks, Lauren Banks, Luke Banks, Paul Banks, Oliver Bannister, Bharat Bansal, Robert Banthorpe, Laura Banton, Mariamma Baptist, Tanya Baqai, Ananya Mouli Baral, Desislava Baramova, Alex Barber, Russel Barber, Emma Barbon, Miriam Barbosa, Monica Barbosa, Jamie Barbour, Alexander Barclay, Claire Barclay, George Bardsley, Stephanie Bareford, Shahedal Bari, Amy Barker, Debbie Barker, Helen Barker, Joseph Barker, Leon Barker, Oliver Barker, Kerry Barker-Williams, Sinha Barkha, Juliana Barla, Gavin Barlow, Richard Barlow, Valerie Barlow, James Barnacle, Alex Barnard, Debi Barnes, Nicky Barnes, Theresa Barnes, Calum Barnetson, Amy Barnett, Matthew Barnett, Ashton Barnett-Vanes, William Barnsley, Andrew Barr, David Barr, Shaney Barratt, Manuella Barrera, Amy Barrett, Fiona Barrett, Jessica Barrett, Joe Barry, Jazz Bartholomew, Claire Bartlett, Georgina Bartlett, Greg Barton, Jill Barton, Lorna Barton, Rachael Barton, Rosaleen Baruah, Sonia Baryschpolec, Archana Bashyal, Betsy Basker, Ayten Basoglu, Gilda Bass, John Bassett, G Bassett, Chris Bassford, Pavinder Bassi, Betsy Bassis, Bengisu Bassoy, Victoria Bastion, Anupam Basumatary, Tristan Bate, Harry J Bateman, Ian Bateman, Kathryn Bateman, Vhairi Bateman, Eleanor Bates, Hayley Bates, Michelle Bates, Simon Bates, Sally Batham, Ana Batista, Amit Batla, Dushyant Batra, Donna Batty, Harry Batty, Thomas Batty, Peter Baughan, Miranda Baum, Carina Bautista, Fareha Bawa, Fatima S Bawani, Simon Bax, Lydia Baxter, Matt Baxter, Nicola Baxter, Zachary Baxter, Hannah Bayes, Charlotte Baylem, Lee Bayliss, Eileen Bays, Farid Bazari, Rohit Bazaz, Ahmad Bazli, Laura Beacham, Wendy Beadles, Philip Beak, Andy Beale, Kirk Beard, Jack Bearpark, Karen Beaumont, Dawn Beaumont-Jewell, Theresa Beaver, Sarah Beavis, Christy Beazley, Sarah Beck, Virginia Beckett, Rosie Beckitt, Heidi Beddall, Seonaid Beddows, Deborah Beeby, Gail Beech, Michelle Beecroft, Sally Beer, Jane Beety, Gabriela Bega, Alison Begg, Susan Begg, Sara Beghini, Ayesha Begum, Salman Begum, Selina Begum, Teresa Behan, Jasmine Beharry, Roya Behrouzi, Jon Beishon, Claire Beith, James Belcher, Holly Belfield, Katherine Belfield, Ajay Belgaumkar, Dina Bell, Gareth Bell, Gill Bell, Gillian Bell, Joshua Bell, Lauren Bell, Louise Bell, Nicholas Bell, Pippa Bell, Stephanie Bell, Jennifer L Bell, Jennifer Bellamu, Mary Bellamy, Arianna Bellini, Amanda Bellis, Fionn Bellis, Lesley Bendall, Naveena Benesh, Nicola Benetti, Leonie Benham, Guy Benison-Horner, Alexander Bennett, Ann Bennett, Caroline Bennett, Christopher Bennett, Gillian Bennett, Ian Bennett, Kristopher Bennett, Lorraine Bennett, Sara Bennett, Karen Bennion, Vivienne Benson, Jane Benstead, Andrew Bentley, Dionne Bentley, James Bentley, Ian Benton, Eva Beranova, Matthew Beresford, Colin Bergin, Malin Bergstrom, Jolanta Bernatoniene, Thomas Berriman, Zoe Berry, Marnie Berwick, Kimberley Best, Ans-Mari Bester, Yvonne Beuvink, Emily Bevan, Sarah Bevins, Tom Bewick, Andrew Bexley, Sonay Beyatli, Fenella Beynon, Arjun Bhadi, Sanjay Bhagani, Shiv Bhakta, Rekha Bhalla, Khushpreet Bhandal, Kulbinder Bhandal, Ashwin Bhandari, Sangam Bhandari, Aashutosh Bhanot, Ravina Bhanot, Sruti Bhaskara, Prashanth Bhat, Nikhil Bhatia, Rahul Bhatnagar, Karan Bhatt, Janki Bhayani, Deepika Bhojwani, Salimuzzaman Bhuiyan, Anna Bibby, Fatima Bibi, Naheeda Bibi, Salma Bibi, Tihana Bicanic, Sarah Bidgood, Julie Bigg, Sarah Biggs, Alphonsa Biju, Andras Bikov, Sophie Billingham, Jessica Billings, Carron Bilton, Teodirico Binas, Martin Binney, Alice Binns, Muhammad BinRofaie, Oliver Bintcliffe, Catherine Birch, Jenny Birch, Louann Birch, Janet Birchall, Katherine Birchall, Sam Bird, Sumedha Bird, Charndip Biring, Mark Birt, Raquel Bisa, Kilanalei Bishop, Linda Bishop, Lisa Bishop, Karen Bisnauthsing, Nibedan Biswas, Sahar Biuk, Karen Blachford, Ethel Black, Helen Black, Karen Black, Mairead Black, Polly Black, Hayley Blackgrove, Bethan Blackledge, Joanne Blackler, Samantha Blackley, Helen Blackman, Stuart Blackmore, Caroline Blackstock, Loraine Blackwood, Francesca Blakemore, Helen Blamey, Alison Bland, Sujata Blane, Simon Blankley, Mary Blanton, Parry Blaxill, Jenny Blaxland, Katie Blaylock, Jane Blazeby, Carol Blears, Natalie Blencowe, Donna Blofield, Ben Bloom, Jack Bloomfield, Angela Bloss, Hannah Bloxham, Louise Blundell, Andrew Blunsum, Mark Blunt, Ian Blyth, Kevin Blyth, Andrew Blythe, Karen Blythe, Marilyn Boampoaa, Boniface Bobie, Karen Bobruk, Pritesh Bodalia, Neena Bodasing, Tanya Bodenham, Sherin Bodh, Gabriele Boehmer, Marta Boffito, Kristyna Bohmova, Sumit Bokhandi, Maria Bokhar, Saba Bokhari, Sakina Bokhari, Syed Owais Bokhari, Ambrose Boles, Sarah Bollington, Sam Bolton, Charlotte Bomken, Charlotte Bond, Hayley Bond, Helena Bond, Stuart Bond, Thomas Bond, Alice Bone, Georgia Boniface, Wendy Bonnert, Lizzy Bonney, Leigh Boorman, Catherine Booth, Joanne Borbone, Cameron Borhani, Naomi Borman, Rachel Borrell, Mamu Boshir, Fiona Bottrill, Laura Bough, Hayley Boughton, Zoe Boult, Miriam Bourke, Stephen Bourke, Michelle Bourne, Rachel Bousfield, Lucy Boustred, Darren Bowen, Kaye Bowen, Alexandra Bowes, Amy Bowes, Philip Bowker, Louise Bowman, Simon Bowman, Rachel Bowmer, Angie Bowring, Geoff Bowyer, Helen Bowyer, Carmel Boyd, Jenny Boyd, Laura Boyd, Maxine Boyd, Namoi Boyle, Pauline Boyle, Rosalind Boyle, Louise Boyles, Osman Bozdag, Leanna Brace, David Brack, Charlotte Brackstone, Rob Bradburn, Jodie Bradder, Barry Bradley, Clare Jane Bradley, Pamela Bradley, Patrick Bradley, Paul Bradley, Joanne Bradley-Potts, Lynne Bradshaw, Sarah Bradshaw, Zena Bradshaw, Rebecca Brady, Shirin Brady, Denise Braganza, Suhail Brailsford, Jill Braithwaite, Marie Branch, Thomas Brankin-Frisby, Jamie Brannigan, Louise Brassington, Sophie Brattan, Fiona Bray, Nancy Bray, Angela Brazier, Manny Brazil, Lucy Brear, Tracy Brear, Stephen Brearey, Laura Bremner, Morwenna Brend, Giovanna Bretland, Chris Brewer, Hannah Bridge, Gavin Bridgwood, Hayley Briggs, Mark Briggs, Sara Brigham, John Bright, Chris Brightling, Lutece Brimfield, Elaine Brinkworth, Robin Brittain-Long, Vianne Britten, Terri Brittin, Lauren Broad, Sarah Broad, Rosie Broadhurst, Andrew Broadley, Marie Broadway, Christopher Brockelsby, Megan Brocken, Tomos Brockley, Andrew Broderick, Mary Brodsky, Fiona Brogan, David Broggio, Liz Brohan, Felicity Brokke, Jacob Brolly, David Bromley, Hannah Brooke-Ball, Verity Brooker, Ceri Brookes, Matthew Brookes, Alison Brooks, Karen Brooks, Nicole Brooks, Philip Brooks, Rachel Brooks, Sophie Brooks, Natalie Broomhead, Chloe Broughton, Nathaniel Broughton, Matt Brouns, Marie Browett, Alison Brown, Ammani Brown, Carly Brown, Catrin Brown, Chloe Brown, Elizabeth Brown, Ellen Brown, Heather Brown, Janet Brown, Louise Brown, Niall Brown, Pauline Brown, Rachel Brown, Richard Brown, Robert Brown, Steven Brown, Tom Brown, Wayne Brown, Bria Browne, Charlotte Browne, Duncan Browne, Mitchell Browne, Stephen Brownlee, Alba Brraka, David Bruce, Johanna Bruce, Michelle Bruce, Wojciech Brudlo, Nigel Brunskill, Alan Brunton, Margaret Brunton, Mandy Bryan, Meera Bryant, April Buazon, Maya Buch, Julie Buchan, Ruaridh Buchan, Alexis Buchanan, Ruaridh Buchanan, Danielle Buche, Amanda Buck, Matthew Buckland, Laura Buckley, Philip Buckley, Sarah Buckley, Carol Buckman, Kathleen Buckmire, George Bugg, Ramadan Bujazia, Marwan Bukhari, Shanze Bukhari, Richard Bulbulia, Alex Bull, Damian Bull, Rhian Bull, Thomas Bull, Naomi Bulteel, Kasun Bumunarachchi, Roneleeh Bungue-Tuble, Caroline Burchett, Dorota Burda, Christy Burden, Thomas G Burden, Mika Burgess, Paula Burgess, Richard Burgess, Sophia Burgess, Paula Burgett, Adrian Burman, Sara Burnard, Caroline Burnett, John Burnett, Amanda Burns, Amy Burns, Collette Burns, James Burns, Karen Burns, Samuel Burns, Sarah Burns, Daniel Burrage, Sadie Burrage, Kate Burrows, Claire Burston, Ben Burton, Fiona Burton, Matthew Burton, Angela Busby, Deborah Butcher, Aaron Butler, Jessica Butler, Joanne Butler, Joshua Butler, Lesley Butler, Peter Butler, Susan Butler, Al-Tahoor Butt, Mohammad M Butt, Sophia Butt, Caryl Butterworth, Nicola Butterworth-Cowin, Robert Buttery, Tom Buttle, Heather Button, Daniel Buttress, Jane Byrne, Wendy Byrne, Victoria Byrne-Watts, Eleanor Byworth, Amanda Cabandugama, Ruth Cade, Anthony Cadwgan, Donna Cairney, James Calderwood, Darren Caldow, Moira Caldwell, Giorgio Calisti, Debbie Callaghan, Jennifer Callaghan, Claire Callens, Donaldson Callum, Caroline Calver, Melissa Cambell-Kelly, Tracey Camburn, David R Cameron, Eleanor Cameron, Fraser Cameron, Sarah Cameron, Sheena Cameron, Christian Camm, Renee F D Cammack, Alison Campbell, Amy Campbell, Barbara Campbell, Bridget Campbell, Debbie Campbell, Helen Campbell, Hilary Campbell, Jonathan Campbell, Mark Campbell, Robyn Campbell, Wynny Campbell, Quentin Campbell Hewson, Julie Camsooksai, Ana Canabarro, Lisa Canclini, Shaula Mae Candido, Janie Candlish, Cielito Caneja, Johnathon Cann, Ruby Cannan, Emma Cannon, Michael Cannon, Petra Cannon, Vivienne Cannons, Jane Cantliff, Ben Caplin, Santino Capocci, Noemi Caponi, Angelika Capp, Anne Capps-Jenner, Thomas Capstick, Ishmael Carboo, Nuria Cardenas, Mary Cardwell, Rachel Carey, Simon Carley, Tammy Carlin, Andrew Carlton, Samantha Carmichael, Mandy Carnahan, Rebecca Carnegie, Charlotte Caroline, Emily Carpenter, Jodi Carpenter, David Carr, Sharon Carr, Anna Carrasco, Samantha Carrington, Zoe Carrington, Paul Carroll, Caroline Carron, Anne Carstairs, Jonathan Carter, Michael Carter, Moira Carter, Paul Carter, Penny Carter, Steven Carter, Simon Carter-Graham, Douglas Cartwright, Jo-Anne Cartwright, Claire Carty, Sinead Carty, Jaime Carungcong, Carolyn Carveth-Marshall, Susan Casey, Annie Cassells, Barbara Cassimon, Teresa Castiello, Gail Castle, Bridget Castles, Melanie Caswell, Ana Maria Catana, Heidi Cate, Susanne Cathcart, Katrina Cathie, Christine Catley, Laura Catlow, Matthew Caudwell, Jill Caulfield, Anna Cavazza, Luke Cave, Simon Cavinato, Frianne Cawa, Kathryn Cawley, Chloe Caws, Hankins Cendl, Hannah Century, Jeva Cernova, Mansur Cesay, Ed Cetti, Stephanie Chabane, Manish Chablani, Cathleen Chabo, David Chadwick, Julie Chadwick, Robert Chadwick, Ela Chakkarapani, Arup Chakraborty, Mallinath Chakraborty, Mollika Chakravorty, James Chalmers, Richard Chalmers, Georgina Chamberlain, Sarah Chamberlain, Emma Chambers, Jonathan Chambers, Lucy Chambers, Naomi Chambers, Alex Chan, Carmen Chan, Cheuk Chan, Evelyn Chan, Kayen Chan, Kimberley Chan, Ping Chan, Rebekah (Pui-Ching) Chan, Xin Hui Chan, Chris Chandler, Heidi Chandler, Kim J Chandler, Stuart Chandler, Zoe Chandler, Vikki Chandler-Vizard, Sumit Chandra, Navin Chandran, Badrinathan Chandrasekaran, Cherry Chang, Yvonne Chang, Josephine Chaplin, Graeme Chapman, John Chapman, Katie Chapman, Laura Chapman, Lianne Chapman, Polly Chapman, Timothy Chapman, Lucy Chappell, Linda Chapple, Amanda Charalambou, Bethan Charles, Dianne Charlton, Sally Charlton, Kevin Chatar, Calvin Chatha, Ritesh Chaube, Muhammad YN Chaudhary, Iram Chaudhry, Nazia Chaudhuri, Muhammad Chaudhury, Anoop Chauhan, Ruchi S Chauhan, Vipul Chauhan, Nicola Chavasse, Iknam Chaven, Rosanna Chavez, Vipal Chawla, Maria Cheadle, Lindsay Cheater, James Cheaveau, Charlotte Cheeld, Michelle Cheeseman, Fang Chen, Hui Min Chen, Terence Chen, Lok Yin Cheng, Zhihang Cheng, Helen Chenoweth, Chun How Cheong, Shiney Cherian, Suzanne Cherif, Mary Cherrie, Helen Cheshire, Barry Chesterson, Betty Cheung, Chee Kay Cheung, Elaine Cheung, Michelle Cheung, Claire Cheyne, Swati Chhabra, Wei Ling Chia, Eric Chiang, Angela Chiapparino, Rosavic Chicano, Zviedzo A Chikwanha, Sam Chilcott, Phillipa Chimbo, KokWai Chin, Wen Jie Chin, Rumbidzai Chineka, Amol Chingale, Karen Chinn, Vashira Chiroma, Heather Chisem, Claire Chisenga, Ben Chisnall, Carolyn Chiswick, Sunder Chita, Nihil Chitalia, Matthew Chiu, Brenda Chivima, Catherine Chmiel, Soha Choi, Willy Choon Kon Yune, Vandana Choudhary, Sarah Choudhury, Bing-Lun Chow, Fateha Chowdhury, Mahibbur Chowdhury, Shahid Chowdhury, Victoria Christenssen, Peter Christian, Alexander Christides, Fiona Christie, Daniel Christmas, Thereza Christopherson, Mark Christy, Paris Chrysostomou, Yunli Chua, Shabs Chucha, Dip Chudgar, Richard Chudleigh, Srikanth Chukkambotla, Michael E Chukwu, Izu Chukwulobelu, Chi Y Chung, Ben Church, Elaine Church, Sara R Church, David Churchill, Nicole Cianci, Nick Ciccone, Paola Cicconi, Paola Cinardo, Zdenka Cipinova, Bessie Cipriano, Sarah Clamp, Melanie Clapham, Edel Clare, Sarbjit Clare, Andrew Clark, Charlotte Clark, Diane Clark, Felicity Clark, Gabrielle Clark, James Clark, Katherine Clark, Kaylea Clark, Louise Clark, Lucy Clark, Matthew Clark, Patricia Clark, Richard Clark, Thomas Clark, Wendy Clark, Zoe Clark, Andrea Clarke, Heather Clarke, Mark Clarke, Paul Clarke, Robert Clarke, Roseanne Clarke, Samantha Clarke, Sarah Clarke, Sheron Clarke, Tracy Clarke, Andrew Clarkson, Alleyna Claxton, Kate Clay, Elizabeth Clayton, Olivia Clayton, Jill Clayton-Smith, Chris Cleaver, Carlota Clemente de la Torre, Jayne Clements, Suzanne Clements, Francesca Clemons, Lee Clifford, Lynne Clifford, Rachael Clifford, Sarah Clifford, Amelia Clive, Jonathan Clouston, Samantha Clueit, Andrea Clyne, Michelle Coakley, Peter G L Coakley, Tony Coates, Kathryn Cobain, Alexandra Cochrane, Patricia Cochrane, Maeve Cockerell, Helen Cockerill, Shirley Cocks, Rachel Codling, Adam Coe, Samantha Coetzee, David Coey, Danielle Cohen, Jonathan Cohen, Oliver Cohen, Mike Cohn, Louise Coke, Olutoyin Coker, Nicholas Colbeck, Roghan 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Davies, Ffyon Davies, Helen Davies, James Davies, Jane Davies, Jeni Davies, Jim Davies, Karen Davies, Kelly Davies, Kim Davies, Louisa Davies, Mark Davies, Matthew Davies, Michelle Davies, Nina Davies, Owen Davies, Patrick Davies, Rachel Davies, Rhys Davies, Ruth Davies, Sarah Davies, Simon Davies, Alison Davis, Gwyneth Davis, Illinos Davis, Julie-Ann Davis, Katherine Davis, Peter Davis, Alexander Davison, Sophia Davison, Mark Davy, Christine Dawe, H Dawe, Mark Dawkins, Danielle Dawson, Elizabeth Dawson, Joy Dawson, Susan Dawson, Tom Dawson, Andrew Daxter, Andrew Day, Helena Day, Jacob Day, Jeremy Day, Lynn Day, Jamie D'Costa, Parijat De, Duneesha de Fonseka, Toni de Freitas, Frederico De Santana Miranda, Eleanor de Sausmarez, Shanika de Silva, Thushan de Silva, Jessica De Sousa, Paulo De Sousa, James de Souza, Anthony de Soyza, Natasha de Vere, Johannes de Vos, Bethan Deacon, Sharon Dealing, Anna Dean, Julie Dean, Katrina Dean, Stephen Dean, Tessa Dean, Jill Deane, James Dear, Effie Dearden, Alison Deary, Catherine Deas, Samuel Debbie, Gabor Debreceni, Vashist Deelchand, Matthew Deeley, Joanne Deery, Emmanuel Defever, Raji Dehulia, Max Deighton, Manuela Del Forno, Arnold Dela Rosa, Lisa Delaney, Amanda Dell, Carrie Demetriou, David DeMets, Jane Democratis, Jacqueline Denham, Emmanuelle Denis, Laura Denley, Craig Denmade, Kathy Dent, Martin Dent, Elise Denton, Tom Denwood, Nishigandh Deole, Darshita Depala, Maria Depante, Randle Derbyshire, Susan Dermody, Amisha Desai, Asmita Desai, Purav Desai, Sanjeev Deshpande, Vai Deshpande, Brendan Devine, Sirjana Devkota, Nicola Dewland, Prakash Dey, Vishal Dey, Rogin Deylami, Jazz Dhaliwal, Kevin Dhaliwal, Jas Dhalliwal, Mandeep Dhanda, Sundip Dhani, Amandeep Dhanoa, Mili Dhar, Devesh Dhasmana, Aman Dhesi, Ekanjali Dhillon, Reiss Dhillon, Pamela Diamond, Priya Dias, Stephanie Diaz, Kayleigh Diaz-Pratt, Debbie Dickerson, Pamela Dicks, Stuart Dickson, Julie Dijo, Sean Dillane, Sarah Diment, Paul Dimitri, Maria Dineen, ThaiHa Dinh, Tri Dinh, Alex Dipper, Laura Dirmantaite, Lisa Ditchfield, Sarah Diver, Lavanya Diwakar, Caroline Dixon, Giles Dixon, Stephen Dixon-Mould, Brice Djeugam, Petr Dlouhy, Laurence Dobbie, Marinela Dobranszky Oroian, Charlotte Dobson, Lee Dobson, Marie Docherty, David Dockrell, James Dodd, Jackie Dodds, Rebecca Dodds, Steve Dodds, Richi Dogra, Erin Doherty, Warren Doherty, Yumiko Doi, Iain Doig, Eleanor Doke, Daniel Dolan, Mark Dolman, Rozzie Dolman, Lisa Donald, Callum Donaldson, Christopher Donaldson, Denise Donaldson, Gillian Donaldson, Kate Donaldson, Joanne Donnachie, Christopher Donnelly, Eilish Donnelly, Ronan Donnelly, Aravindhan Donohoe, Gemma Donohoe, Bryan Donohue, Sinead Donton, Emma Dooks, Grainne Doran, Kane Dorey, Sharon Dorgan, Amanda Dornan, Moonira Dosani, Davinder Dosanjh, Paula Dospinescu, Katie Douglas, Jonathan Douse, Lucy Dowden, Michelle Dower, Kerry Dowling, Sud Dowling, Nicola Downer, Charlotte Downes, Rob Downes, Thomas Downes, Damian Downey, Philippa 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Eagles, Joanne Early, Melissa Earwaker, Nicholas Easom, Clare East, Kim East, Amy Easthope, Fraser Easton, Caroline Eaton, Caroline Eaton-Howell, Ruth Eatough, Adrian Ebbs, Oluwadamilola Ebigbola, Daniel Ebner, Martin Ebon, Sinan Eccles, Chloe Eddings, Michael Eddleston, Maureen Edgar, Katharine Edgerley, Nicholas Edmond, Julie Edmonds, Dave Edmondson, Mary Edmondson, Tracy Edmunds, Alexandra Edwards, Catherine Edwards, Joy Edwards, Kennedy Edwards, Mandy Edwards, Tomos Edwards, Jenny Eedle, Dawn Egginton, Loveth Ehiorobo, Sarah Eisen, Ugochukwu Ekeowa, Mohamed Ekoi, Ayomide Ekunola, Soha El Behery, Moulod El-Agnaf, Mohamed Elbeshy, Kate El-Bouzidi, Jennifer Elder, Mohammed El-Din, Diana Eleanor, Ibrahim Eletu, Eman Elfar, Mayy Magdy Elgamal, Amr Elgohary, Stellios Elia, Jennifer Elias, Tania Elias, Nadia Elkaram, Mohammed El-Karim, Andrew Victor Elkins, Julie Ellam, Nikki Ellard, Laura Nicola Ellerton, Lucy Elliot, Amy Elliott, Chris Elliott, Fiona Elliott, Kerry Elliott, Scott Elliott, Toby Elliott, Annie Ellis, Ann-Marie Ellis, Christine Ellis, Kay Ellis, Kaytie Ellis, Tak-Yan Ellis, Yvette Ellis, Megan Ellison, Rahma Elmahdi, Einas Elmahi, Hannah-May Elmasry, Mohammed Elmi, Najla Elndari, Omer Elneima, Mohamed Elokl, Ahmed Elradi, Mohamed Elsaadany, Sally El-Sayeh, Hana El-Sbahi, Tarek Elsefi, Karim El-Shakankery, Robert Elshaw, Hosni El-Taweel, Sarah Elyoussfi, Jonathan Emberey, Jonathan R Emberson, John Emberton, Julian Emmanuel, Ingrid Emmerson, Michael Emms, Florence Emond, Marieke Emonts, Nicu Enachi, Angila Engden, Katy English, Emma Entwistle, Hene Enyi, Marios Erotocritou, Helen Escreet, Peter Eskander, Hanif Esmail, Lise Estcourt, Amy Evans, Brynach Evans, Chris Evans, Daren Evans, Debra Evans, Gail Evans, Gareth Evans, Jennifer Evans, Lisa Evans, Lynn Evans, Margaret Evans, Michelle Evans, Mim Evans, Morgan Evans, Ranoromanana Evans, Ryan Evans, Teriann Evans, Terry John Evans, Tony Eve, Caroline Everden, Serenydd Everden, Hayley Evison, Lynsey Evison, Penny Eyton-Jones, Jacqueline Faccenda, Leila Fahel, Youstina Fahmay, Sara Fairbairn, Terry Fairbairn, Andy Fairclough, Louise Fairlie, Mark Fairweather, Anne Fajardo, Naomi Falcone, Euan Falconer, Jonathan Falconer, John Fallon, Andrea Fallow, David Faluyi, Victoria Fancois, Qayyum Farah, Novin Fard, Amr Farg, Margaret Farinto, Adam Farmer, Katie Farmer, Toni Farmery, Samantha Farnworth, Faiyaz Farook, Hadia Farooq, Sidrah Farooq, Fiona Farquhar, Karen Farrar, Aaron Farrell, Barbara Farrell, James Farthing, Syeda Farzana, Rahmatu Fasina, Azam Fatemi, Mina Fatemi, Nibah Fatimah, Maria Faulkner, Saul N Faust, Joe Fawke, Sinmidele Fawohunre, Abul Fazal, Kelly Feane, Simon Fearby, Alex Feben, Federico Fedel, Daria Fedorova, James Feely-Henderson, Christopher Fegan, Mae Felongco, Lynsey Felton, Tim Felton, Kate Fenlon, Andrea Fenn, Isabelle Fenner, Ciara Fenton, Melisa Fenton, Cameron Ferguson, Jenny Ferguson, Kathryn Ferguson, Katie Ferguson, Stephanie Ferguson, Susan Ferguson, Susie Ferguson, Victoria Ferguson, Denzil Fernandes, Candida Fernandez, Eduardo Fernandez, Maria Fernandez, Sonia Fernandez Lopez, Callum Jeevan Fernando, Ahmed Feroz, Pietro Ferranti, Thais Ferrari Gersogamo, Eleanor Ferrelly, Alexandra Ferrera, Emma Ferriman, Nicholas Fethers, Ben Field, Janet Field, Rebecca Field, Karen Fielder, Lindsey Fieldhouse, Andra Fielding, Julie Fielding, Len Fielding, Sarah Fielding, Asma Fikree, Sarah Ann Filson, Sarah Finbow, Debbie Finch, Joanne Finch, Laurie Finch, Joanne Finden, Natalie Fineman, Lauren Finlayson, Adam Finn, Joanne Finn, Clare Finney, Sofia Fiouni, Jo Fiquet, Dani Fisher, Emily Fisher, James Fisher, Neil Fisher, Meadow Fisher Crisp, Daniel Fishman, Krystofer Fishwick, Lorraine Fitzgerald, Chloe Fitzpatrick-Creamer, Jan Flaherty, Michael Flanagan, Charles Flanders, Cathy Flatters, Julie Fleming, Lucy Fleming, Paul Fleming, William Flesher, Alison Fletcher, Jonathan Fletcher, Lucy Fletcher, Simon Fletcher, Sophie Fletcher, Karen Flewitt, Christopher Flood, Ian Floodgate, Vincent Florence, Sharon Floyd, Kelly Flynn, Rachel Flynn, Sara Flynn, Claire Foden, Adama Fofana, Georgina Fogarty, Claire Foley, Paul Foley, Linda Folkes, Daniela Mock Font, Evodian Fonyonga, Aiwyne Foo, Jane Foo, Andrew Foot, Jayne Foot, Jane Forbes, Jamie Ford, Kathy Ford, Jennifer Foreman, Caroline Fornolles, Adam Forrest, Ellie Forsey, Miranda Forsey, Thomas Forshall, Elliot Forster, Julian Forton, Emily Foster, Joseph Foster, Rachel A Foster, Tracy Foster, Theodora Foukanelli, Angela Foulds, Ian Foulds, Folakemi Fowe, Emily Fowler, Robert Fowler, Stephen Fowler, Caroline Fox, Claire Fox, Daniel Fox, Heather Fox, Jonathan Fox, Lauren Fox, Natalie Fox, Olivia Fox, Simon Fox, Sarah-Jane Foxton, Yasin Fozdar, Rebecca Frake, Alex Francioni, Olesya Francis, Rebecca Francis, Sarah Francis, Theodora Francis-Bacon, Jason Frankcam, Helen Frankland, Gayle Franklin, Jessica Franklin, Darron Franks, Catherine Fraser, Laura Fraser, Sharon Frayling, Martyn Fredlund, Matthew Free, Carol Freeman, Elaine Freeman, Hannah Freeman, Nicola Freeman, Clare Freer, Ian Freestone, Eleanor French, Matthew Frise, Renate Fromson, Claire Froneman, Adam Frosh, John Frost, Victoria Frost, Oliver Froud, Rachel Frowd, Arun Fryatt, Jake Fryer, Janet Fu, Bridget Fuller, Liz Fuller, Neil Fuller, Tracy Fuller, Duncan Fullerton, Jenny Fullthorpe, Carrie Fung, Gayle Fung, Sarah Funnell, John Furness, Charlene Furtado, Andrew Fyfe, Nytianandan G, Elizabeth Gabbitas, Claire Gabriel, Diana Gabriel, Hadiza Gachi, Rose Gad, Joshua Gahir, Sarveen Gajebasia, Katarzyna Gajewska-Knapik, Zacharoula Galani, Christopher Gale, Hugo Gale, Rebecca Gale, Swetha Gali, Karen Galilee, Bernadette Gallagher, Jude Gallagher, Rosie Gallagher, William Gallagher, Joanne Galliford, Catherine Galloway, Chris Galloway, Emma Galloway, Jacqui Galloway, James Galloway, Laura Gamble, Liz Gamble, Brian Gammon, Jaikumar Ganapathi, Ramesh Ganapathy, Kaminiben Gandhi, Sarah Gandhi, Usha Ganesh, Abrar Gani, Emma-James Garden, Antoni D Gardener, Emma Gardiner, Jill Gardiner, Michael Gardiner, Phil Gardiner, Siobhan Gardiner, Caroline Gardiner-Hill, Jonathan Gardner, Mark Garfield, Atul Garg, Nathan Garlick, Justin Garner, Lucie Garner, Zoe Garner, Kimberley Garnett, Robert Garney, Rosaline Garr, Michael Garstka, Peter Gartan, Florence Garty, Rachel Gascoyne, Hyeriju Gashau, Noha Gasmalseed, Michaela Gaspar, Aoife Gatenby, Erin Gaughan, Alok Gaurav, Mariana Gavrila, Jane Gaylard, Emma Gaywood, Catherine Geddie, Alison Geddis, Ian Gedge, Sarah Gee, Minerva Gellamucho, Karzan Gelly, Leila Gelmon, Sandra Gelves-Zapata, Gemma Genato, Susan Gent, Natalie Geoghegan, Chloe George, Sam George, Tina George, Simon Georges, Domonique Georgiou, Peter Gerard, Leigh Gerdes, Louise Germain, Helen Gerrish, Abel Getachew, Louise Gethin, Hisham Ghanayem, Amardeep Ghattaoraya, Anca Gherman, Alison Ghosh, Justin Ghosh, Sudhamay Ghosh, Sarra Giannopoulou, Malick Gibani, Andrew Gibb, Ben Gibbison, Kerry Gibbons, Alex Gibson, Bethan Gibson, Kimberley Gibson, Kirsty Gibson, Sian Gibson, Cat Gilbert, Jeanette Gilbert, Joanne Gilbert, Kayleigh Gilbert, Sean Gilchrist, Benjamin Giles, Mandy Gill, Rose Gill, Lynne Gill, Paul Gillen, Annelies Gillesen, Katherine Gillespie, Matt Gillespie, Elizabeth Gillham, Andrew Gillian, Deborah Gilliland, Robert Gillott, Danielle Gilmour, Kate Gilmour, Theodora Giokanini-Royal, Anna Gipson, Joanna Girling, Rhian Gisby, Angelena Gkioni, Aikaterini Gkoritsa, Effrossyni Gkrania-Klotsas, Amy Gladwell, James Glanville, Jessica Glasgow, Susannah Glasgow, Jon Glass, Lynn Glass, Sharon Glaysher, Lisa Gledhill, Ana Glennon, John Glover, Kyle Glover, Jan Glover Bengtsson, Chevanthy Gnanalingam, Julie Goddard, Wendy Goddard, Emily Godden, Jo Godden, Gillian Godding, Emma Godson, Gerry Gogarty, Sukanya Gogoi, Aiky Goh, Rebeca Goiriz, Sriya Gokaraju, Philip Gold, Raphael Goldacre, Arthur Goldsmith, Portia Goldsmith, Darren Gomersall, Lucia Gomez, Raquel Gomez-Marcos, Ali Gondal, Celia Gonzalez, Jack Goodall, Bob Goodenough, Laura Goodfellow, James Goodlife, Camelia Goodwin, Elizabeth Goodwin, Jayne Goodwin, Paula Goodyear, Rajiv Gooentilleke, Sharif Goolam-Hossen, Michelle Goonasekara, Sheila Gooseman, Shameer Gopal, Peter Gordon, Sally Gordon, Hugh Gorick, Caitlin Gorman, Claire Gorman, Stuart Gormely, Diana Gorog, Jan Gorry, Michelle Gorst, Thomas Gorsuch, Jayshreebahen Gosai, Rebecca Gosling, Sally Gosling, Georgina Gosney, Vanessa Goss, Dzintars Gotham, Naomi Gott, Elizabeth Goudie, Amanda Gould, Angela Gould, Susan Gould, Lysander Gourbault, Anna Gouveia, Abha Govind, Sharon Gowans, Girish Gowda, Rohit Gowda, Pauline Gowdy, Hannah Gower, Thomas Gower, Pankaj Goyal, Sunil Goyal, Sushant Goyal, Beverley Graham, Clive Graham, Jane Graham, Jonathan Graham, Justin Graham, Libby Graham, Sharon Graham, Matthew Graham-Brown, Julia Grahamslaw, Gianluca Grana, Tracyanne Grandison, Louis Grandjean, Alison Grant, Ann Grant, David Grant, Matthew Grant, Pauleen Grant, Rhys Gravell, Jenny Graves, Alasdair Gray, Catherine Gray, Georgina Gray, Harriet Gray, Ingrid Gray, Jackie Gray, Karen Gray, Nicola Gray, Sebastian Gray, Alan Grayson, Patricia Grealish, Fiona Greaves, Jack Greaves, Paul Greaves, Charlotte Green, Christopher Green, David Green, Frederick Green, Grace Green, Joel Green, Marie Green, Nicola Green, Stacey Green, Teresa Green, Diarra Greene, Philippa Greenfield, Alan Greenhalgh, Maraneka Greenslade, Daniel Greenwood, Sandra Greer, James Gregory, Jane Gregory, Katie Gregory, Tamsin Gregory, James Gregson, Jill Greig, Julia Greig, Rebecca Grenfell, Teena Grenier, Susan Grevatt, Glaxy Grey, Andrew Gribbin, Amy Gribble, Beverley Grice, Natasha Grieg, Douglas Grieve, Ben Griffin, Denise Griffin, Mel Griffin, Sian Griffith, Alexandra Griffiths, Andrew Griffiths, Daniel Griffiths, David Griffiths, Donna Griffiths, Isabel Griffiths, Mark Griffiths, Nicola Griffiths, Oliver Griffiths, Sarah Griffiths, Sharon 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Jennie Hale, Carmel Halevy, Paul Halford, William Halford, Alistair Hall, Anthony Hall, Claire Hall, Elizabeth Hall, Emma Hall, Fiona Hall, Helen Hall, Jennifer Hall, Kathryn Hall, Bill Hall, Jan Hallas, Kyle Hallas, Charles Hallett, Becky-Lee Halls, Heather Halls, Maryam Hamdollah-Zadeh, Bilal Hameed, Imran Hamid, Mohamad Hamie, Bethany Hamilton, Fergus Hamilton, Leigh Hamilton, Nicola Hamilton, Ruth Hamlin, Eleanor Hamlyn, Beatrice Hammans, Shirley Hammersley, Kate Hammerton, Bev Hammond, Leah Hammond, Sara Hammond, Fiona Hammonds, Ibrahim Hamoodi, Karen Hampshire, Elizabeth Hampson, Jude Hampson, Lucy Hampson, Ozan Hanci, Ian Hancock, Sadiyah Hand, Jasmine Handford, Soran Handrean, Sarah Haney, Sheharyar Hanif, E Hanison, Alison Hanlon, Jennifer Hannah, Amy Hannington, Merhej Hannun, Aidan Hanrath, Anita Hanson, Jane Hanson, Kathryn Hanson, Steve Hanson, Helen Hanwell, Mazhar Ul Haq, Ala Haqiqi, Monjurul Haque, Lesley Harden, Zoe Harding, Simon Hardman, Joanna Hardy, Kumar Haresh, Rachel Harford, Beverley Hargadon, Carolyn Hargreaves, Emily Hargreaves, James Hargreaves, Alice Harin, Mohammed Haris, Edward Harlock, Sandra Harlow, Paula Harman, Tracy Harman, Mark Harmer, Muhammad A Haroon, Charlie Harper, Fiona Harper, Heather Harper, Melanie Harper, Peter Harper, Rosemary Harper, Sarah Harrhy, Sian Harrington, Yasmin Harrington-Davies, Jade Harris, Jess Harris, John Harris, Laura Harris, Marie-Clare Harris, Naomi Harris, Nichola Harris, Sophie Harris, Alex Harrison, David Harrison, Julie Harrison, Laura Harrison, Melanie Harrison, Rowan Harrison, Susie Harrison, Thomas Harrison, Wendy Harrison, Elizabeth Harrod, Ciaran Hart, Dominic Hart, Lisa Hartley, Rosemary Hartley, Ruth Hartley, Tom Hartley, William Hartrey, Phillipa Hartridge, Stuart Hartshorn, Heli Harvala, Alice Harvey, Angela Harvey, Max Harvey, Catherine Harwood, Helen Harwood, Brigitte Haselden, Kazi Hashem, Mohammed Hashimm, Tadaaki Hashimoto, Imranullah Hashmi, Sarah Haskins, Zena Haslam, Adil Hassan, Ali Hassan, Wagae UI Hassan, Waqar Ul Hassan, Sapna Hassasing, Jane Hassell, Philip Hassell, Alex Hastings, Bethany Hastings, Janice Hastings, Stephanie Hatch, Jonathan Hatton, Sheryl Haviland, May Havinden-Williams, Stefan Havlik, Daniel B Hawcutt, Kadean Hawes, Liz Hawes, Nicola Hawes, Annie Hawkins, Catherine Hawkins, Nancy Hawkins, Tanya Hawkins, Dan Hawley, Ed Hawley-Jones, Edward Haworth, Cathy Hay, Amna Hayat, Jamal Hayat, Mohamed-Riyal Hayathu, Tamsin Haydon, Anne Hayes, Jonas Hayes, Kate Hayes, Melony Hayes, Vanessa Hayes, Fiona Hayes, Patrick Hayle, Chloe Haylett, Antara Hayman, Melanie Hayman, Matthew Haynes, Richard Haynes, Rachel Hayre, Sarah Haysom, James Hayward, Patrick Haywood, Tracy Hazelton, Phoebe Hazenberg, Zhengmai He, Elizabeth Headon, Carrie Heal, Brendan Healy, Amy Hearn, Angela Heath, Rowan Heath, Diane Heaton, Kerry Hebbron, Gemma Hector, Andy Hedges, Katrine Hedges, Cheryl Heeley, Elaine Heeney, Rajdeep Heire, Ulla Hemmila, Cassie Hemmings, Scott Hemphill, Deborah Hemsley, Abigail Henderson, Jennifer Henderson, Steven Henderson, Lee Hennen, Kathryn Hennessy, Natalie Hennesy, Carol Ann Henry, Joanne Henry, Karol Henry, Lavinia Henry, Margo Henry, Natalie Henry, David Henshall, Mike Herbert, Gillian Herdman, Rosaleen Herdman-Grant, Morag Herkes, Emma Heron, Kay Heron, William Herrington, Emilia Heselden, Peta Heslop, Sharnie Beth Hesson, Simon Hester, Emily Hetherington, Joseph Hetherington, Chamila Hettiarachchi, Pramodh Hettiarachchi, Hayley Hewer, John Hewertson, Anna Hewetson, Sue Hewins, Jacqueline Hewitson, Claire Hewitt, Davina Hewitt, Richard Hewitt, Robert Heyderman, Nicolette Heydon, Mathis Heydtmann, Joseph Heys, Jonathan Heywood, Gareth Heywood-Beldon, Meg Hibbert, John Hickey, Naomi Hickey, Peter Hickey, Alex Hicks, Jenny Hicks, Rosie Hicks, Scott Rory Hicks, Daniel Higbee, Lucy Higgins, Andrew Higham, Martin Highcock, Judith Highgate, Mondy Hikmat, Alison Hill, Amanda Hill, Helen Hill, Joanne Hill, Lisa Hill, Martin Hill, Phoebe Hill, Uta Hill, Annette Hilldrith, Elizabeth Hillerby, Catherine Hillman-Cooper, Elisabeth Hilton, Zoe Hilton, Sarah Hinch, Marcus Hinde, Andrew Hindle, Alice Hindmarsh, Paul Hine, Kim Hinshaw, Clare Hird, Alison Hirst, Jemma Hives, Benson Ho, Michaela Hoare, David Hobden, Gill Hobden, Maria Hobrok, Simon Hobson, Renate Hodge, Simon Hodge, Lesley Hodgen, Holly Hodgkins, Louise Hodgkinson, Sally Hodgkinson, David Hodgson, Helen Hodgson, Luke Hodgson, Sheila Hodgson, Gemma Hodkinson, Kenneth Hodson, Matthew Hogben, Lucy Hogg, Lee Hoggett, Abigail Holborow, Catherine Holbrook, Catherine Holden, Melinda Holden, Thomas Holder, Niels Holdhof, Hannah Holdsworth, Lisa Holland, Maureen Holland, Nicky Holland, Marie Hollands, Elizabeth Holliday, Nina Holling, Gillian Hollis, Laszlo Hollos, Linda Holloway, Simon Holloway, Marcus Hollyer, Amy Holman, Ann Holmes, Benjamin Holmes, Megan Holmes, Raphael Holmes, Rebecca Holmes, Kelly Holroyd, Caroline Holt, Lyndsey Holt, Siobhan Holt, Susie Holt, Alexandra Holyome, Marie Home, Toni Home, Renate Homewood, Kate Hong, Laura Hontoria del Hoyo, Clare Hooper, Sarah Hoosdally, Samantha Hope, Susan Hope, Bridget Hopkins, Peter W Horby, Stephanie Horler, Anil Hormis, Daniel Hornan, Nicola Hornby, Zoey Horne, Latoya Horsford, Megan Horsford, Mark Horsford, Valana Horsham, Alexander Horsley, Ashley Horsley, Elizabeth Horsley, Sarah Horton, Nicola Horton-Turner, Jane Hosea, Toby Hoskins, Muhammad S Hossain, Rashed Hossain, Leanne Hostler, Maxine Hough, Sarah Hough, Brittany Houghton, Catherine Houghton, Iain Houghton, Kathryn Houghton, Rebecca Houlihan, Angela Houston, Hamish Houston, Tawedzegwa Hove, Roseanna Hovvels, Lee How, Laura Howaniec, Laura Howard, Linda Howard, Lucy Howard, Sarah Howard, Stuart Howard, Richard Howard-Griffin, Alison Howarth, Diane Howarth, Serena Howe, Mark Howells, Lyn Howie, Kerry Howlett, Sophie Howlett, Joanne Hoyle, Josh Hrycaiczuk, Naing Zaya Htoon, Su Htwe, Ying Hu, Chiang Ooi Huah Huah, Abby Huckle, Shahzya Huda, Alison Hudak, Lisa Hudig, Alex Hudson, Cara Hudson, Heather Hudson, Peter Hudson, Oli Hudson, Alison Hufton, Connor Huggins, Alistair Hughes, Eithne Hughes, Emma Hughes, Gareth Hughes, Heather Hughes, Luke Hughes, Rachel Hughes, Rebecca Hughes, Samantha Hughes, Stephen Hughes, Vikki Hughes, Wesley Hughes, Lukas Huhn, Ching Hui, Ruth Hulbert, Diana Hull, Grace Hull, Robert Hull, Amanda Hulme, Peter Hulme, Wendy Hulse, George Hulston, Ryan Hum, Laura Humber, Megan Hume, Charlotte Humphrey, Ismay Humphreys, Alasdair Humphries, Joanne Humphries, Lena Hunold, Fiona Hunt, Kristen Hunt, Luke Hunt, Sophie Hunt, Al Hunter, Alexandra Hunter, Isobel Hunter, Karl Hunter, Neil Hunter, George Huntington, Elizabeth Hurditch, Cian Hurley, Katrina Hurley, Mohammed A Husain, Syeda Yusra Husaini, Coralie Huson, Afreen Hussain, Ibraar Hussain, Ifza Hussain, Mohammad Hussain, Muhammad Hussain, Reda Hussain, Sajid Hussain, Samia Hussain, Sanniah Hussain, Wasim Hussain, Yasmin Hussain, Mohammed Hussam El-Din, Raheem Hussein, Rebecca Hussey, Camille Hutchinson, Dorothy Hutchinson, Elizabeth Hutchinson, John Hutchinson, Claire Hutsby, Paula Hutton, Daniella Hydes, Jamie Hyde-Wyatt, Niamh Hynes, Megan Hyslop, Mazen Ibraheim, Abdalla Ibrahim, Ahmed Ibrahim, Asil Ibrahim, Mohamed Ibrahim, Monzeer Ibrahim, Wadah Ibrahim, Adetokunbo I Idowu, Muhammad Idrees, Hina Iftikhar, Mawara Iftikhar, Chukwuemeka Igwe, Mohammad Ijaz, Amaju Ikomi, Clare Iles, Stamatina Iliodromiti, Mary Ilsley, Lorna Ilves, La'ali Imam-Gutierrez, Christopher Imray, Alison Imtiaz, Haider Imtiaz, Claire Ingall, Jack Ingham, Julie Ingham, Rory Ingham, Tejas Ingle, Jennifer Inglis, Anne Ingram, Luke Ingram, Peter Inns, Ken Inweregbu, Andreea A Ionescu, Ana Ionita, Ilian P Iordanov, Anil Ipe, Adil Iqbal, Madiha Iqbal, Mohammed Iqbal, Faisal Iqbal Sait, Jane Ireland, Robert Irons, Mohannad Irshad, Muhammad S Irshad, Janice Irvine, Val Irvine, Pamela Irving, Robert Irving, Mina Ishak, Erica Isherwood, Aminul Islam, Abdurrahman Islim, Ali Ismail, Omar Ismail, Caroline Ison, M'hamedi Israa, Sharon Isralls, Ali Issa, Monica Ivan, Catrina Ivel, Chineze Ivenso, Ashleigh Ivy, Sophie Iwanikiw, Karen Ixer, Menaka Iyer, Mia Iyer, Calum Jack, Amanda Jackson, Anthony Jackson, Ben Jackson, Beth Jackson, Douglas Jackson, Ella Jackson, Hayley Jackson, Helen Jackson, Jane Jackson, Julie Jackson, Karin Jackson, Lauren Jackson, Melanie Jackson, Nicola Jackson, Shane Jackson, Sharon Jackson, Nikita Jacob, Patricia Jacob, Reni Jacob, Nicola Jacques, Terri-Lisa Jacques-Brown, Anisa Jafar, Daniel Jafferji, Ali Jaffery, Chandrashekar Jagadish, Vijay Jagannathan, Sam Jaggard, Mandeep Jagpal, Fernandez R Jaime, Neemisha Jain, Seema Jain, Susan Jain, Sanjay Jaiswal, Danyal Jajbhay, Thomas Jaki, Bintou Jallow, Yusuf Jaly, Sabine Jamal, Zeba Jamal, Yasmin Jameel, Albie James, Christie James, Kate James, Lee James, Linda James, Mark James, Nicholas James, Olivia James, Rebecca James, Ruth James, Tracy James, Jack Jameson, Aaron Jamison, Phoebe Jane, Azara Janmohamed, Sabrina Jansz, Deepa Japp, Lorraine Jappy, Victor Jardim, Catherine Jardine, Emma Jarnell, Ellie Jarvie, Ann Jarvis, Claire Jarvis, Lisa Jarvis, Rosina Jarvis, Patrycja Jastrzebska, Hafsa Javed, Mays Jawad, Lona Jawaheer, Kauky Jawaid, Anu Jayachandran, Dinakaran Jayachandran, Angelina Jayakumar, Deepak Jayaram, Ravi Jayaram, Geeshath Jayasekera, Thilina Jayatilleke, Abi Jayebalan, Saman Jeddi, Vandana Jeebun, Mohammad S Jeelani, Zeynab Jeewa, Emma Jefferson, Katie Jeffery, Helen Jeffrey, Jenni Jeffrey, Rachel Jeffrey, Sue Jeffrey, Nathan Jeffreys, Benjamin Jeffs, Debbie Jegede, Taylor Jemima, Ifan Jenkin, Alison Jenkins, Christopher Jenkins, David Jenkins, Elinor Jenkins, Sarah Jenkins, Sian Jenkins, Stephen Jenkins, Jacqui Jennings, Louise Jennings, Rebecca Jennings, Virginia Jennings, Ellen Jerome, Douglas Jerry, Ellen Jessup-Dunton, Jorge Antonio Jesus Silva, Champa Jetha, Kishan Jethwa, Jeby Jeyachandran, Visuvanathan Jeyakumar, Dharshana Jeyapalan, Shaman Jhanji, Khoo Jian, Zhixin Jiao, Laura Jimenez, Ana Jimenez Gil, Jithin Jith, Teishel Joefield, Navraj Johal, Karine Johannessen, Aisyah Johari, Annie John, Anu John, Navin John, Sarah John, Emma Johns, Margaret Johns, Anne-Marie Johnson, Antoinette Johnson, David Johnson, Emma Johnson, Gillian Johnson, Kathryn Johnson, Katie Johnson, Luke Johnson, Mark Johnson, Nelsonseelan Johnson, Oliver Johnson, Rachel Johnson, Tracy Johnson, Zoe Johnson, Claire Johnston, Janet Johnston, Laura Johnston, Susan Johnston, Victoria Johnston, Dawn Johnstone, Ed Johnstone, Janet Johnstone, Manohar Joishy, Adam Jones, Alistair Jones, Annabel Jones, Ben Jones, Bryony Jones, Carys Jones, Ceri Jones, Charlotte Jones, Christine E Jones, Debra Jones, Emily Jones, Gareth Jones, Geraldine Jones, Hazel Jones, Jac Jones, James Jones, Jamie Jones, Jessica Jones, Jonathon Jones, Julie Jones, Karen Jones, Kate E Jones, Kevin Jones, Laura Jones, Laura M Jones, Lorna Jones, Louise Jones, Mathew Jones, Nicola Jones, Paul Jones, Rhianna Jones, Ruth E Jones, Samantha Jones, Sophie Jones, Stefanie Jones, Steve Jones, Taya Jones, Tim Jones, Tracey Jones, Ramya Jonnalagadda, Rebecca Jordache, Annette Jose, Sanal Jose, Anna Joseph, Joseph Joseph, Rosane Joseph, Sibet Joseph, Dhaara Joshi, Mehul Joshi, Pratichi Joshi, Revati Joshi, Benz Josiah, Tiffany Joyce, Adriel Ju Wen Kwek, Edward Jude, Parminder Judge, Jessica Juhl, Sirisha Jujjavarapu, Mark Juniper, Edmund Juszczak, Deepthi Jyothish, Kasamu Kabiru Dawa, Mark Kacar, Katarina Kacinova, Nikhil Kadam, Rebecca Kahari, Gail Kakoullis, Azad Kala Bhushan, Richard JK Kalayi, Roobala Kaliannan Periyasami, Efthymia Kallistrou, Seika Kalsoom, Elisa Kam, John Kamara, Mohamed Kamara, Ajay Kamath, Prakash Kamath, Ravindra Kamath, Siddharth Arun Kamerkar, Nick Kametas, Musaiwale Kamfose, Arul Kandaswamy, Leia Kane, Osei Kankam, Thogulava Kannan, Abhinav Kant, Vikas Kapil, Ritoo Kapoor, Sonal Kapoor, Sourjya Kar, Janaka Kara, Vasita Kara, Marina Karakantza, Rona Kark, Nicholas Karunaratne, Natashja Kasianczuk, Vidya Kasipandian, Rizwan Kassam, Janarth Kathirgamachelvam, Victoria Katsande, Kulbinder Kaul, Daljit Kaur, Dervinder Kaur, Jasmin Kaur, Jaspreet Kaur, Satvinder Kaur, Zunaira Kausar, Mohammad AA Kawser, Andrea Kay, Sarah Kay, Jossy N Kayappurathu, Callum Kaye, Ahemd Kazeem, Naved Kazi, Sharon Kaznica, Samantha Kearley, Rachel Kearns, Nichola Kearsley, Joanne Keating, John Keating, Liza Keating, Elizabeth Keddie-Gray, Katie Keen, Natalie Keenan, Jonathan Kefas, Stephen Kegg, Laura Keith, Uzoamaka Keke, Tosin Kelani, Joanne Kellett, Jeremy Kellington, Alison Kelly, Conor Kelly, David Kelly, Diane Kelly, Dominic Kelly, Emma Kelly, Laura Kelly, Martin Kelly, Michael Kelly, Rosalind Kelly, Sinead Kelly, Stephen Kelly, Thomas Kelly, Mary Kelly-Baxter, Marketa Keltos, Timothy Kemp, Kelly Kemsley, Alexandra Kendall-Smith, Sarah Kennard, Ann Kennedy, Caroline Kennedy, James Kennedy, Sophie Kennedy-Hay, Julia Kenny, Kelly Kent, Melanie Kent, Lynne Keogan, Alexander Keough, Clement Kerlin, A Kerr, Andrew Kerr, Maria Kerr, Caroline Kerrison, Anthony Kerry, Samantha Kershaw, Helen Kerslake, Ian Kerslake, Helen Kerss, Jocelyn Keshet-Price, Margaret Kevern, Georgina Keyte, Abdul Khadar, Ali Khalid, Muhammad U Khalid, Syed Khalid, Amir Khalil, Asma Khalil, Sijjad Khalil, Abubakar Khan, Ali Khan, Al-Imran Khan, Arham Khan, Asad Khan, Aurangzeb Khan, Burhan Khan, Camran Khan, Fatimah Khan, Kausik Khan, Malik Aamaz Khan, Marria Khan, Mehrunnisha Khan, Mohammad Khan, Mohammed Khan, Nayeem Khan, Omar Khan, Rahe Khan, Rahila Khan, Sabiya Khan, Shabana Khan, Shahul Khan, Shoaib Khan, Tasaduksultan Khan, Waseem Khan, Usman F Khatana, Jibran Khatri, Jyoti Khatri, Hafiza Khatun, Taslima Khatun, Mena Kheia, Jacyntha Khera, Htet Ei Khin, Najaf Khoja, Kiran Khokhar, Jayne Khorsandi, Chloe Khurana, Faith Kibutu, Andrew Kidd, Michelle Kidd, Joe Kidney, Shane Kidney, Will Kieffer, James Kilbane, Caroline Kilby, Eileen Killen, Susan Kilroy, Bomee Kim, Jee Whang Kim, Sarah Kimber, Andy King, Barbara King, Jennifer King, Kirsten King, Rachel King, Sarah King, Tony King, Victoria King, Emily King-Oakley, Laura Kingsmore, Andy King-Venables, Fiona Kinney, Sidra Kiran, Jeremy Kirk, Jodie Kirk, Daniel Kirkbride, Amy Kirkby, Ian Kirker, Emily Kirkham, Gemma Kirkman, Ursula Kirwan, Kelly Kislingbury, Toby Kitching, Laura Kitto, Lauren Kittridge, Sarah Klaczek, Frieder Kleemann, Susan Kmachia, Chris Knapp, Lucy Knibbs, Alicia Knight, Fraser Knight, Marian Knight, Sarah Knight, Steven Knight, Tom Knight, Ellen Knights, Jane Knights, Toby Knights, Martin Knolle, Carol Knott, Charlotte Knowles, Karen Knowles, Laurence Knowles, Emily Knox, Lucy Knox, Oliver Koch, Ronan Kodituwakku, Gouri Koduri, Aisha Koirata, Eirene Kolakaluri, Magdalena Kolodziej, Eirini Kolokouri, Keith Kolsteren, Samantha Kon, Niladri Konar, Mari Kononen, Athanasios Konstantinidis, Hui Fen Koo, Imogen Koopmans, Emmanuela Kopyj, Laura Korcierz, James Korolewicz, George Koshy, Chris Kosmidis, Jalpa Kotecha, Easwari Kothandaraman, Leonidas Koukouflis, Koushan Kouranloo, Rukhsana Kousar'c, Margarita Kousteni, Maja Kovac, Alex Kozak Eskenazia, Kestutis Krasauskas, Raghu Krishnamurthy, Vinodh Krishnamurthy, Manju Krishnan, Hari Krishnan, Suzanne Krizak, Sean Krupej, Agnieszka Kubisz-Pudelko, Soren Kudsk-Iversen, Aurimas Kudzinskas, Chirag Kukadiya, Nainesha Kulkarni, Aditi Kumar, Mayur Kumar, Ramesh Kumar, Ravi Kumar, Rita Kumar, Rupa Kumar, Satish Kumar, Vimal Kumar, Arun Kundu, Heinke Kunst, Amit Kurani, Mohammed Kurdy, Rincy Kurian, Vimal Kurmars, Cameron Kuronen-Stewart, Ranganai S Kusangaya, Vlad Kushakovsky, Mandy Kuunal, Apexa Kuverji, Amma Kyei-Mensah, Thyra Kyere-Diabour, Moe Kyi, Nyan M Kyi, Laura Kyle, Karali-Tsilimpari Kyriaki, Julius Labao, Louise Lacey, Nikki Lack, Emma Ladlow, Heather Lafferty, Shondipon Laha, Sushil Lahane, Clement Lai, James Lai, Emma Laing, Robert Laing, Inez Laing-Faiers, Emily Laity, Michelle Lake, Nicki Lakeman, David Lalloo, Fiona Lalloo, Alison Lam, Fiona Lamb, Lucy Lamb, Thomas Lamb, Nick Lambe, Pauline Lambert, Claudia Lameirinhas, Mohammed KG Lami, Abigail Lamikanra, Holly Lamont, Michal Lamparski, Djillali Lamrani, Christine Lanaghan, Rebecca Lanaway, Ivone Lancona-Malcolm, Julia Lancut, Geraldine Landers, Martin J Landray, Matthew Lane, Nicholas Lane, Alidih Lang, Stephen Lang, Daniel Langer, Margaret Langley, Charles Langoya, Emily Langthorne, Taiya Large, Wojciech Lason, Anna Last, Scott Latham, John Latham-Mollart, Afzal Latheef, Darren Latimer, Nang Latt, Carly-Jane Lattimore, Dawn Lau, Eva Lau, Myra Laurenson, Hou Law, Jennifer Law, Jessica Law, Penny Law, Richard Law, Colin Lawler, Mark Lawley, Emma Lawrence, Jo Lawrence, Neil Lawrence, Ryan Lawrie, Jemima Lawson, Joanne Lawson, Louise Lawson, Rebecca Lawton, Michael Lay, Christine Laycock, Reina Layug, Maria Lazo, Vietland Le, Amelia Lea, William Lea, Ian Leadbitter, Thomas Leahy, Richard Lean, Lorna Leandro, Darren Leaning, Sandra Leason, Christina Leaver, Marie Anne Ledingham, Emma Lee, Hannah Lee, Irish Lee, Judith Lee, Sam Lee, Shi Han Lee, Simon Lee, Sindy Lee, Stephanie Lee, Tracey Lee, Xiang Lee, Diana Lees, Jennifer Lees, Helen Legge, Julian Leggett, Katie Leigh-Ellis, Kevan Leighton, Nicky Leitch, Eleni Lekoudis, Petula Lemessy, Nicholas Lemoine, Joana Lemos, Irina Lenchuk, Katy Leng, Katrina Lennon, Liz Lennon, Isabel Lentell, Kelly Leonard, Wen Leong, Nicky Leopold, Oskar Lepiarczyk, Isla Leslie, Eleni Lester, Joe Leung, Ullrich Leuschner, Emma Levell, Chris Levett, Alice Lewin, Michaela Lewin, Alison Lewis, David Lewis, Dee Lewis, Georgina Lewis, Gillian Lewis, Joanne Lewis, Joseph Lewis, Kathryn Lewis, Keir Lewis, Leon Lewis, Lisa Lewis, Marissa Lewis, Rob Lewis, Robert Lewis, Catherine Lewis-Clarke, Lorraine Lewis-Prosser, Katherine Lewiston, Adam Lewszuk, Penny Lewthwaite, Samantha Ley, Anna Li, Jenny Li, Angela Liao, Victoria Licence, David Lieberman, Susan 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Kaatje Lomme, Emily London, Gabriella Long, Natalie Long, Bev Longhurst, Mark Longshaw, Jennifer Lonnen, Caroline Lonsdale, Laura Looby, Ronda Loosley, Paola Lopez, Paula Lopez, Robert Lord, Stuart Lord, Laura Lordache, Kieron Loregnard, Catherine Lorenzen, Claire Lorimer, Francesco Loro, Rachel Lorusso, Eva Loutraris, Robert Loveless, Maxine Lovell, Angeliki Loverdou, Huw Lovett, Daniel Loveys, Andrew Low, Jen Mae Low, Alastair Lowe, Caroline Lowe, Catherine Lowe, Emily Lowe, Faye Lowe, Michael Lowe, Linda Lowrey, Richard Lowsby, Vicki Lowthorpe, Emma Loxley, Gamu Lubimbi, Alexandra Lubina Solomon, Georgia Lucas, Jacob Lucas, Alice Lucey, Olivia Lucey, Suzanne Luck, H Luke, Jane Luke, Hayley Lund, Apurva Lunia, Muriel Lunn, Ji Luo, Julia Lussier, Cindy Nisha Luximon, Elisa Ly, Barrie Lyell, Elisavet Lyka, Sarah Lymn, Audrey Lynas, Ceri Lynch, Daniel Lynch, Daniella Lynch, Stephen Lynch, Helen Lyon, Rea-Grace Maamari, Hannah Mabb, Louies Mabelin, Jessica Macaro, Angela Macauley, Kateryna Macconaill, Chloe Macdonald, Stuart MacDonald, Tania MacDonald, Claire Macfadyen, James G Macfarlane, Jill Macfarlane, Laura Macfarlane, Cara MacGuigan, Lisa MacInnes, Iain MacIntyre, Jill MacIntyre, Kirsten Mack, Callum Mackay, Euan Mackay, Laura Mackay, Alexander Mackenzie, Matt Mackenzie, Robert MacKenzie Ross, Ami Mackey, Patricia Mackey, Fiona Mackie, Robert Mackie, Carolyn Mackinlay, Claire Mackintosh, Katherine Mackintosh, Sheila MacLennan, Mary Joan MacLeod, Michael Macmahon, Andrew MacNair, Catherine Macphee, Iain Macpherson, Catriona Macrae, Allan MacRaild, Eilidh MacVean, Alannah Madden, Mary Madden, Norman Madeja, Karen Madgwick, Pradeep Madhivathanan, Madhavi Madhusudhana, Harriet Madiyiko, Alpha Madu, Lorraine Madziva, Marion Mafham, Nick Magee, Frederick Magezi, Tim Maggs, Negar Maghsoodi, Christopher Magier, Marios Magriplis, Kathryn Maguire, Natasha Mahabir, Subramanian Mahadevan-Bava, Anjanie Maharajh, Ajit Mahaveer, Bal Mahay, Kanta Mahay, Hibo Mahdi, 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Margarit, Georgios Margaritopoulos, Mike Margarson, Fernandez M Maria del Rocio, Teresa Maria Pfyl, Victor Mariano, Helen Maria-Osborn, Ashleigh Maric, Grace Markham, John Markham, Maria Marks, Pamela Marks, Elisabeth Marouzet, Arran Marriott, Cheryl Marriott, Nemonie Marriott, Brian Marsden, Karen Marsden, Paul Marsden, Sarah Marsden, Tracy Marsden, Robyn Marsh, Adam Marshall, Andrew Marshall, Gail Marshall, Henry Marshall, Jaimie Marshall, James Marshall, Jenna Marshall, Nicola Marshall, Riley Marshall, Jennifer Marshall, Samantha Marston, Emmeline Martin, Hayley Martin, Hope Martin, Jane Martin, Karen Martin, Kate Martin, Laila Martin, Michael Martin, Noelia Martin, Tim Martin, Winston Martin, Sarah Martin, Tim Martindale, Marcus Martineau, Alexander Martinez, Lauren Martinez, Jose Carlos Martinez Garrido, Juan Martin-Lazaro, Olivia Martins, Lucas Martins Ferreira, Vijay Kumar Maruthamuthu, Gemma Maryan, Roman Mary-Genetu, Sam Maryosh, Vidan Masani, Diego Maseda, Sheila Mashate, 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McEleavy, Julie McEnerney, Julie McEntee, Evanna McEvoy, Ruth McEwen, Margaret McFadden, Denise McFarland, Margaret McFarland, Rachel McFarland, Erin McGarry, Lorcan McGarvey, Margaret McGarvey, Clodagh McGettigan, Michael McGettrick, Christopher McGhee, Fiona McGill, Sarah McGinnity, Hannah McGivern, Neil McGlinchey, Phil McGlone, Deborah McGlynn, Claire McGoldrick, Clare McGoldrick, Elizabeth McGough, Margaret McGovern, Brendan McGrath, Amanda McGregor, Annemarie McGregor, Cathryn McGuinness, Heather McGuinness, Sean McGuire, Tara McHugh, Caroline McInnes, Neil McInnes, Karen McIntyre, Mhairi McIntyre, Carolyn McKay, Lorna McKay, Conor P McKeag, Madeleine McKee, Joseph McKeever, Shirley McKenna, Donogh McKeogh, Denise Mckeown, Caroline McKerr, Anthony M McKie, Claire Mckie, Laura Mckie, Gerard McKnight, Heather McLachlan, Andrew McLaren, Barbara McLaren, Nicola McLarty, Maria McLaughlin, James McLay, Mary McLeish, Tina McLennan, Lorna McLintock, Stewart McLure, Amanda McMahon, Anne 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Nagarajan, Imrun Nagra, Deepak Nagra, Mina Naguib, Kirushthiga Naguleswaran, K Shonit Nagumantry, Kevin Naicker, Sarveshni Naidoo, Gireesha Naik, Rishi Naik, Samir Naik, Devu S Nair, Rajiv Nair, Tanushree Nair, Jay Naisbitt, Kerry Naismith, Sri Nallapareddy, Soum Nallapeta, Arumugan Nallasivan, Uttam Nanda, Aarti Nandani, Ali Raza Naqvi, Asadullah Naqvi, Sara Naqvi, Shruthi Narayan, Sophia Nasa, Dominic Nash, Nader Nasheed, Abdul Nasimudeen, Umer Nasir, Marwan Nassari, Tahir Nasser, Anushka Natajaran, Anuja Natarajan, Geetha Natarajan, Nalin Natarajan, Nikhila Natarajan, Rajkumar Natarajan, Noel Nathaniel, Mala Nathvani, Priyan Nathwani, George Nava, Neena Navaneetham, Jeya Navaratnam, Helen Navarra, Sadaf Naveed, John Navin, Khuteja Nawaz, Sarfaraz Nawaz, Shasta Nawaz, Bonilla Nayar, Suzanne Naylor, Moez Nayyar, Farrah Naz, Mobeena Naz, Salima Nazarali, Babak Nazari, S Nazir, Sehar Nazir, Dumisani Ncomanzi, Onyine Ndefo, Alan Neal, Elaine Neary, Mostafa Negmeldin, Paula Neill, Hector 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Tanaraj Perinpanathan, Lakshmi Periyasamy, Francesca Perkins, Rachel Perkins, Elizabeth Perritt, Alison Perry, Emily Perry, Meghan Perry, Terrie Perry, Thomas M Perumpral, Guilherme Pessoa-Amorim, Ruth Petch, Lionel Peter, Cecilia Peters, Craig Peters, Jayne Peters, Mark Peters, Steve Peters, Tim Peters, Remy Petersen, Alexandra Peterson, Leon Peto, Iulia Petras, Ilianna Petrou, Boyanka Petrova, Mirela Petrova, Paul Pfeffer, Mysore Phanish, Paul Phelan, Christopher Philbey, Jennifer Philbin, Neil Philips, Alex Phillips, Danielle Phillips, Dylan Phillips, Karen Phillips, Pat Phillips, Rachael Phillips, Katherine Philpott, Marie Phipps, Virach Phongsathorn, Mandeep Phull, Masroor M Phulpoto, Myat TT PI, Sara Pick, James Pickard, Charlotte Pickering, Gillian Pickering, Thomas Pickett, Hayleah Pickford, Joanna Pickles, Benjamin Pickwell-Smith, Natalia Pieniazek, Charlie Piercy, Angelo Pieris, Samia Pilgrim, Paul Anthony Pillai, Zoe Pilsworth, Heather Pinches, Stacey Pinches, Julia Pinder, 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Raj, Pradeep Rajagopalan, Nithy Rajaiah, Arvind Rajasekaran, Aylur Rajasri, Thurkka Rajeswaran, Jyothi Rajeswary, Jeyanthy Rajkanna, Gayathri Rajmohan, Ruth Rallan, David Ralphs, Katherine Ralston, Maximilian Ralston, Matsa Ram, Balaji Ramabhadran, Fathima Ramali, Mohamed Ramali, Athimalaipet Ramanan, Shashikira Ramanna, Maheshi Ramasamy, Dhanishta Ramdin, Jozel Ramirez, Mylah Ramirez, Geshwin Ramnarain, Lidia Ramos, Shanthi Ramraj, Alex Ramshaw, Aleem Rana, Ghulam F Rana, Rehman Rana, Abby Rand, James Rand, Helen Randall, Harpal Randheva, Poonam Ranga, Manmeet Rangar, Harini Rangarajan, Sameer Ranjan, Poormina Ranka, Rajesh Rankhelawon, Haley Ranton, Anita Rao, Sandhya Rao, Sanjay Rao, Deepak Rao, Anuja Rasarathnam, Alia Rashid, Khalid Rashid, Simbisai Ratcliff, Sam Ratcliffe, Sophy Ratcliffe, Sanjeev Rath, Mohmad I Rather, Selina Rathore, Aravinden Ratnakumar, Jonathan Ratoff, Deepa Rattehalli, Jason Raw, Hywel Rawlins, Gautam Ray, Michelle Ray, Adam Raymond-White, Dana Raynard, 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Robinson, Kate Robinson, Katie Robinson, Matthew Robinson, Ryan Robinson, Sandra Robinson, Stacey Robinson, Steve Robson, Lisa Roche, Samantha Roche, Jennifer Rock, Natalie Rodden, Alistair Roddick, Jack Roddy, Marion Roderick, Alison Rodger, Faye Rodger, Megan Rodger, Alicia Rodgers, Deirdre Rodgers, Natasha Rodgers, Penny Rodgers, Vanessa Rodrigues, Rocio Rodriguez-Belmonte, Nicholas Roe, Charles Roehr, Gill Rogers, Jason Rogers, Joanne Rogers, John Rogers, Leigh Rogers, Lindsay Rogers, Louise Rogers, Michaela Rogers, Paula Rogers, Susan Rogers, Thomas Rogers, Sakib Rokadiya, Lee Rollins, Jennifer Rollo, Catherine Rolls, Atal Roman, Claire Rook, Rashmi Rook, Kevin Rooney, Lynsey Rooney, Gemma Roper, Lace P Rosaroso, Alastair Rose, Annie Rose, David Rose, Rachel Rose, Steve Rose, Vikkie Rose, Zoe Rose, Josephine Rosier, Jack Ross, Jenny Rossdale, Andrew Ross-Parker, Alex Rothman, Joanne Rothwell, Lindsay Roughley, Kathryn Rowan, Neil Rowan, Stephen Rowan, Scott Rowan-Ferry, Anna Rowe, Louise Rowe-Leete, Benjamin Rowlands, Megan Rowley, Aparajita Roy, Subarna Roy, Anna Roynon-Reed, Sam Rozewicz, Alison Rudd, Anna Rudenko, Senthan Rudrakumar, Banu Rudran, Shannon Ruff, Prita Rughani, Sharon Rundell, Jeremy Rushmer, Rosemary Rushworth, Darren Rusk, Peter Russell, Richard Russell, Cristina Russo, Marieke Rutgers, Aidan Ryan, Brendan Ryan, Lucy Ryan, Matthew Ryan, Pat Ryan, Phil Ryan, Declan Ryan-Wakeling, Nick Rylance, M Saad, Javeson Sabale, Suganya Sabaretnam, Umar Sabat, Noman Sadiq, Emma Sadler, Maria-Isabel Saez-Garcia-Holloway, Ashiq Saffy, Beth Sage, Harkiran Sagoo, Sobia Sagrir, Rajnish Saha, Sian Saha, Nikhil Sahdev, Sarvjit Sahedra, Jagdeep Sahota, Nooria Said, Sreekanth Sakthi, Hikari Sakuri, Murthy Saladi, Abdul Salam, Sofiyat Salawu, Armorel Salberg, Erika Salciute, Gina Saleeb, Mumtaz Saleh, Hizni Salih, Laylan Salih, Sarah Salisbury, SiteEneye Saliu, Rustam Salman, Angela Salmon, Jenny Salmon, Nichola Salmons, Dario Salutous, Mfon Sam, Sally Sam, Tinashe Samakomva, Renaldo Samlal, Emily Sammons, David Sammut, Mark Sammut, Zoe Sammut, Sunitha Sampath, Claire Sampson, Julia Sampson, Aashna Samson, Anda Samson, Johnson Samuel, Lorraine Samuel, Merna Samuel, Reena Samuel, Thomas DL Samuel, Younan Samuel, Elsward Samuels, Theo Samuels, Joanna Samways, Manjula Samyraju, Francisco San Diego, Ilves Sana, Veronica Sanchez, Amada Sanchez Gonzalez, Alina Sanda-Gomez, Paul Sandajam, Peter Sandercock, Amy Sanderson, Colleen Sanderson, Tom Sanderson, Kuljinder Sandhu, Loveleen Sandhu, Sam Sandow, Victoria Sandrey, Sarah Sands, Mirriam Sangombe, Mathew Sanju, Filipa Santos, Rojy Santosh, Jayanta Sanyal, Aureo F Sanz-Cepero, Dinesh Saralaya, Arun Saraswatula, Joshua Sarella, Avishay Sarfatti, Rebecca Sargent, Beatrix Sari, Khatija Sarkar, Rahuldeb Sarkar, Sruthi Sarma, Zainab Sarwar, Thea Sass, Sonia Sathe, Sobitha Sathianandan, Abilash Sathyanarayanan, Lavanya SJP Sathyanarayanan, Thozhukat Sathyapalan, Prakash Satodia, Vera Saulite, Andrew Saunders, Rachel Saunders, Samantha Saunders, Anne Saunderson, Heather Savill, Karishma Savlani, Gauri Saxena, Matthew Saxton, Amrinder Sayan, Diane Scaletta, Marta Scally, Deborah Scanlon, Jeremy Scanlon, Lyndsay Scarratt, Sean Scattergood, Alvin Schadenberg, Wendy Schneblen, Rebecca Schofield, Samuel Schofield, David Scholes, Karen Scholes, Alex Schoolmeesters, Natasha Schumacher, Nicola Schunke, Martin Schuster Bruce, Karin Schwarz, Antonia Scobie, Tim Scorrer, A. Scott, Alistair Scott, Anne Scott, Catherine Scott, Christine Scott, Emily Scott, Graham Scott, Kathyn Scott, Leanne Scott, Martha Scott, Michelle Scott, Stephen Scott, Timothy Scott, Sarah Scourfield, Wendy Scrase, Angela Scullion, Therese Scullion, Richard Seabury, Emily Seager, Cathy Seagrave, Deborah Seals, Rebecca Seaman, Eleanor Sear, Isabella Seaton, Anna Seckington, Joanna Sedano, Deborah Seddon, Gabrielle Seddon, Muhammad A Seelarbokus, Christopher Sefton, Matias Segovia, Fatima Seidu, Gillian Sekadde, Mallika Sekhar, Faye Selby, Georgina Selby, Jo Sell, Claire Sellar, Katharine Sellers, Joseph Selley, Victoria Sellick, Gobika Selvadurai, Brintha Selvarajah, Haresh Selvaskandan, Subothini S Selvendran, Gary Semple, Nandini Sen, Seema Sen, Aditya Sengupta, Niladri Sengupta, Helen Senior, Peter Senior, Susana Senra, HoJan Senya, Niranjan Setty, Abigail Seward, Teswaree Sewdin, Jack Seymour, Hussam Shabbir, Tracey Shackleton, Fiona Shackley, Tariq Shafi, Aashni Shah, Ahmar Shah, Anand Shah, Bhavni Shah, Momin Shah, Neil Shah, Pallav Shah, Priyank Shah, Qasim Shah, Sarfaraz H Shah, Snehal Shah, Suraj Shah, Syed Shah, Wajid Shah, Saarma Shahad, Sousan Shahi, Sipan Shahnazari, Muhammad Shahzeb, Aisha Shaibu, Zara Shaida, Amina Y Shaikh, Maliha Shaikh, Rajit Shail, Mariya Shaji, Muhammad Shakeel, Korah Shalan, Nadia Shamim, Kazi Shams, Alison Shanahan, Thomas Shanahan, Shaminie Shanmugaranjan, Hamed Sharaf, Muhammad Sharafat, Asir Sharif, Ajay Sharma, Akhilesh Sharma, Ash Sharma, Bhawna Sharma, Mona Sharma, Ojasvi Sharma, Poonam Sharma, Rajeev Sharma, Sanjeev Sharma, Sarkhara Sharma, Shriv Sharma, Sonal Sharma, Alexander Sharp, Charles Sharp, Gemma Sharp, Paula Sharratt, Phoebe Sharratt, Katherine Sharrocks, Emma Sharrod, Christopher Shaw, Daisy Shaw, David Shaw, Deborah Shaw, Joanne Shaw, Jonathan Shaw, Lisa Shaw, Tomos G Shaw, Anna Shawcross, Jill Shawe, Lou Shayler, Khuram Shazad, Sophy Shedwell, Jonathan Sheffield, Zak Shehata, Arshiya Sheik, Asif Sheikh, Noorann Sheikh, Laura Sheldon, Benjamin Shelley, Sarah Shelton, Anil Shenoy, Julie Shenton, Amy Shepherd, Kate Shepherd, Lorna Shepherd, Scott Shepherd, Rhian Sheppeard, Helen Sheridan, Ray Sheridan, Samuel Sherridan, Leanne Sherris, Susanna Sherwin, Shaad Shibly, Roger Shiers, Chiaki Shioi, Anand Shirgaonkar, Kim Shirley, Adebusola Shonubi, Angela Short, Richard Shortland, Rob Shortman, Rohan Shotton, Sarah Shotton, Ervin Shpuza, Nora Shrestha, Karen Shuker, Jack Shurmer, Gilbert Siame, Loria Siamia, Zanele Sibanda, Claire Sidaway, Seshnag Siddavaram, Nasir Siddique, Sohail Siddique, Nyma Sikondari, Claudia Silva Moniz, Mike Silverstone, Malcolm Sim, Theresa Simangan, Vimbai Simbi, Robert Sime, Oliver Simmons, Richard Simms, Merritt Simon, Natalie Simon, Angela Simpson, Anna Simpson, Danny Simpson, Georgina Simpson, Joanne Simpson, John Simpson, Kerry Simpson, Phillip Simpson, Thomas Simpson, Andrew Simpson, Kathryn Simpson, Cindy Sing, Ankita Singh, Claire Singh, Jayaprakash Singh, Jyoti Singh, Lokeshwar Singh, Manjeet Singh, Nadira Singh, Pankaj Singh, Prabhsimran Singh, Salil Singh, Saurabh Singh, Parag Singhal, Bryan Singizi, Manas Sinha, Utkarsh Sinha, Guy Sisson, Sarah Sithiravel, Karthikadevi Sivakumar, Shanmugasundaram Sivakumar, Darsh Sivakumran, Sivanthi Sivanadarajah, Pasupathy-Rajah Sivasothy, Rebecca Sivers, Alison Sivyer, Nicole Skehan, Robert Skelly, Orlagh Skelton, Imogen Skene, Michael J Skill, Denise Skinner, Tabitha Skinner, Victoria Skinner, Agnieszka Skorko, Iwona Skorupinska, Mariola Skorupinska, Amy Slack, Katie Slack, Wendy Slack, Heather Slade, Helen Slade, Mark Slade, Helen Slater, Lynda Slater, Nicola Slawson, Andrew Sloan, Brendan Sloan, Derek Sloan, Geraldine Sloane, Benjamin Small, Ellen Small, Emma Small, Samuel Small, Karen D Smallshaw, Andy Smallwood, Carien Smit, Aileen Smith, Alex Smith, Amanda Smith, Amy Smith, Andrew Smith, Anna Smith, Camilla Smith, Catherine Smith, Chris Smith, Christopher Smith, Dominic Smith, Eleanor Smith, Harriet Smith, Hazel Smith, Helen Smith, Jacky Smith, Janice Smith, Jessica Smith, Juliet Smith, Karen Smith, Kate Smith, Kathryn Smith, Katie Smith, Kelly Smith, Kerry Smith, Lara Smith, Linda Smith, Lisa Smith, Loren Smith, Maria Smith, Mel Smith, Oliver Smith, Rachel Smith, Rebecca Smith, Richard Smith, Ruth Smith, Sally Smith, Samantha Smith, Stacey Smith, Stephanie Smith, Susan Smith, Imogen Smith, John Smith, Gemma Smithson, Sue Smolen, Sara Smuts, Naoise Smyth, Annette Snell, David Snell, Luke Snell, Beng So, Michelle Soan, Toluleyi Sobande, Alberto Sobrino Diaz, Basit Sohail, Bina Sohail, Herminder Sohal, Roy Soiza, Mary Sokolowski, Olajumoke Solademi, Krishma Solanki, Babak Soleimani, Amanda Solesbury, Reanne Solly, Louise Solomon, Subash Somalanka, Chandrashekaraiah Somashekar, Raj Sonia, Shiu-Ching Soo, Deepti Sood, Pavandeep Soor, Germanda Soothill, Jennifer Soren, Youssef Sorour, Apina Sothinathan, Pragalathan Sothirajah, Najwa Soussi, Donna Southam, David Southern, Iain Southern, Louise Southern, Sara M Southin, Jessica Southwell, Thomas Southworth, Jason Sowter, Claudia Spalding, Enti Spata, Katie Spears, Mark Spears, John Spence, Michelle Spence, Branwell Spencer, Gisele Spencer, Sue Spencer, Tom Spencer, Helen Spicer, Rose Spicer, Helen Spickett, Jennifer Spillane, William Spiller, Kerry Spinks, Michelle Spinks, Nick Spittle, Johanna Sporrer, Karen Spreckley, Janet Spriggs, Oliver Spring, Scott Springworth, Gemma Squires, Jack Squires, Rebecca Squires, Ram Sreenivasan, K Sri Paranthamen, Ramesh Srinivasan, Asha Srirajamadhuveeti, Vino Srirathan, Chloe Stacey, Sybil Stacpoole, Louise Stadon, Tony Staincliffe, Jocasta Staines, Nikki Staines, Katie Stammers, Roxana Stanciu, Grazyna Stanczuk, Helen Stannard, Edward Stanton, Robyn Staples, Simon Stapley, Natalie Staplin, Adam Stark, Michelle Starr, Julie Staves, Rached Stead, Anthea Steel, Charlotte Steel, Conor Steele, John Steer, Vergnano Stefania, Paula Stefanowska, Katie Steinert, Caroline Stemp, Alison Stephens, David Stephensen, Elaine Stephenson, Monique Sterrenburg, Georgia Stevens, Guy Stevens, Melanie Stevens, Will Stevens, Amy Stevenson, Andrew Stevenson, Elaine Stevenson, Lesley Stevenson, Sarah Stevenson, Amanda Stewart, Claire Stewart, Colin Stewart, McKenna Stewart, Rachel Stewart, Rebecca Stewart, Richard Stewart, Jo Stickley, Gemma Stiller, Robert Stirk, Sarah Stirrup, Sarah Stock, Alexander Stockdale, Lynne Stockham, Paul Stockton, Emma Stoddard, Chris Stokes, Ben Stone, Roisin Stone, Sarah Stone, Imogen Storey, Kim Storton, Frederick Stourton, Angela Strachan, Catherine Strait, Ellen Strakosch, Emma Stratton, Jane Stratton, Sam Straw, Luke Streeter, Dieter Streit, Emma Stride, Sally Stringer, Sophia Strong-Sheldrake, Siske Struik, Carmel Stuart, Anna Stubbs, Harrison Stubbs, Ann Sturdy, Sharon Sturney, Matt Stuttard, Cristina Suarez, Karuna Subba, Christian P Subbe, Manjula Subramanian, Venkatram Subramanian, Chinari Subudhi, Rebecca Suckling, Srivatsan Sudershan, Lee Sudlow, Gayle Sugden, Peter Sugden, Rudresh Sukla, Ali Suliman, Fatimah Suliman, Ian Sullivan, Sugrah Sultan, Jennifer Summers, Mark Summerton, Samyukta Sundar, Reka Sundhar, Edmond Sung, Nadia Sunni, Jay Suntharalingam, Amitava Sur, Dharmic Suresh, Shilpa Suresh, Rachel Suri, Michael Surtees, Danielle Suter, Helen Sutherland, Rachel Sutherland, Rebecca Sutherland, Dovile Sutinyte, Deborah Sutton, John Sutton, Sam Sutton, Mihaela Sutu, Marie-Louise Svensson, Sima Svirpliene, Andrew Swain, Thomas Swaine, Christopher Swales, Lorna Swan, Nicola Swarbrick, Tirion Swart, Stephen Sweetman, Samaher Sweity, Ealish Swift, Paul Swift, Pauline Swift, Peter Swift, Rachael Swift, Rachel Swingler, Sophie Swinhoe, Katarzyna Swist-Szulik, Luke Swithenbank, Omair Syed, Catriona Sykes, Daisy Sykes, Eliot Sykes, Luke Sylvester, Dominic Symon, Andrew Syndercombe, Zoe Syrimi, Jen Syson, Gemma Szabo, Tamas Szakmany, Megan Szekely, Matthew Szeto, Maria Tadros, Amr Tageldin, Lucy Tague, Hasan Tahir, Muhammad Tahir, Silvia Taibo, Zsofia Takats, Abigail Takyi, Peter Talbot, Alison Talbot -Smith, James Talbot-Ponsonby, Richard Tallent, Bradley Tallon, Phoebe Tamblin-Hopper, Adrian Tan, Bee T Tan, Hock Tan, Huey Tan, Jade Tan, Keith Tan, WeiTeen Tan, Anand Tana, Xiaohui Tang, Christina Tanney, Tabitha Tanqueray, Emma Tanton, Ran Tao, Mark Taplin, Hayley Tarft, Priyal Taribagil, Obaid Tarin, Syed Tariq, Zeeshan Tariq, David Tarpey, Lisa Tarrant, Antonia Tasiou, Elizabeth Tatam, Margaret L Tate, Kate Tatham, Vera Tavoukjian, Alexander Taylor, Beverley Taylor, Brian Taylor, Charlie Taylor, Charlotte Taylor, David Taylor, Elisabeth Taylor, Janet Taylor, Jennifer Taylor, Joanne Taylor, Julie Taylor, Karen Taylor, Leanne Taylor, Margaret Taylor, Matthew Taylor, Melanie Taylor, Natalie Taylor, Rachael Taylor, Rachel Taylor, Samantha Taylor, Suzanne Taylor, Tina Taylor, Tracey Taylor, Vicky Taylor, Michelle Taylor-Siddons, Thomas Taynton, Amelia Te, Jessica Teasdale, Julie Tebbutt, Caroline Tee, Rajni Tejwani, Seble Tekle, Adam Telfer, Vibha Teli, Jennifer Tempany, Holly Templar, Julie Temple, Natalie Temple, Helen Tench, Yi He Teoh, Lynne Terrett, Louise Terry, Abbi Tervit, Dariusz Tetla, Kate Tettmar, Shirish Tewari, Daniel Tewkesbury, Joana Texeira, ChiaLing Tey, Clare Thakker, Manish Thakker, Amirtharajh Tharmakulasingam, Hilary Thatcher, Andrew Thayanandan, Krishna Thazhatheyil, Eaint Thein, Lambrini Theocharidou, Phyu Thet, Kapeendran Thevarajah, Mayooran Thevendra, Nang Thiri Phoo, Yvette Thirlwall, Muthu Thirumaran, Alice Thomas, Andrew Thomas, Caradog Thomas, Emma Thomas, Enson Thomas, Esther Thomas, Hannah Thomas, Helen Thomas, James Thomas, Karen Thomas, Koshy Thomas, Lucy Thomas, Rachel Thomas, Rebecca Thomas, Rhys Thomas, Ruth Thomas, Samantha Thomas, Sarah Thomas, Sherine Thomas, Tessy Thomas, Vicky Thomas, Rhian Thomas-Turner, Samantha Thomas-Wright, Catherine Thompson, Christopher Thompson, Clara Thompson, Fiona Thompson, Katharine Thompson, Laura Thompson, Liz Thompson, Luke Thompson, Michael Thompson, Orla Thompson, Rebecca Thompson, Roger Thompson, Trevor Thompson, Usilla Thompson, Nicola Thomson, Natasha Thorn, Charlotte Thorne, Nicola Thorne, Wendy Thorne, Jim Thornton, Michael Thornton, Richard Thornton, Sara Thornton, Susan Thornton, Thomas Thornton, Tracey Thornton, Allison Thorpe, Christopher Thorpe, Sarah Thorpe, Paradeep Thozthumparambil, Laura Thrasyvoulou, Hannah Thraves, Elisha Thuesday, Vicky Thwaiotes, Guy Thwaites, Simon Tiberi, Jane Tidman, Serena Tieger, Carey Tierney, Caroline Tierney, Mark Tighe, Sorrell Tilbey, Amanda Tiller, John Timerick, Elizabeth Timlick, Alison Timmis, Hayley Timms, Anne-Marie Timoroksa, Samakomva Tinashe, Heather Tinkler, Marianne Tinkler, Jacqui Tipper, Helen Tivenan, Helen T-Michael, Anne Todd, Jackie Todd, Stacy Todd, Mohamed Tohfa, Helena Tollick, Melanie Tolson, Ana Luisa Tomas, Natalia Tomasova, Sharon Tomlin, Simon Tomlins, Jo Tomlinson, James Tonkin, Ivan Tonna, Catherine Toohey, Kirsty Topham, Mathew Topping, Ruhaif Tousis, Peter Tovey, Gareth Towersey, Jason Towler, Jill Townley, Alain Townsend, Chris Townsend, Richard Tozer, Claire Tranter, Helen Tranter, Jonathan Trattles, Christopher Travill, Sarah Traynor, Karis Treuberg, Mike Trevett, Ascanio Tridente, Sanchia Triggs, Fiona Trim, Thomas Trimble, Alex Trimmings, Tom Trinick, Sven Troedson, Emily Tropman, Amy Trotter, Madeleine Trowsdale Stannard, Nigel Trudgill, Maria Truslove, Shaun Trussell, Tariq Trussell, Sara Tryon, Kyriaki Tsakiridou, Christine Tsang, Hoi Pat Tsang, Peter Tsang, Tan Tsawayo, Kyriaki Karali Tsilimpari, Georgios Tsinaslanidis, Simon Tso, Sally Tucker, Victoria Tuckley, Caroline Tuckwell, Aisha Tufail, Redmond Tully, Grace Tunesi, Saidat Turawa, Killiam Turbitt, Anna Turco, Krystyna Turek, Rezon Turel, Tolga Turgut, Claudia Turley, Alison Turnbull, Aine Turner, Ash Turner, Charlotte Turner, David Turner, Frances Turner, Gail Turner, Kate Turner, Kelly Turner, Louise Turner, Lucy Turner, Marc Turner, Mark Turner, Patricia Turner, Ruth Turner, Sally Turner, Samantha Turner, Susan Turner, Victoria Turner, Sharon Turney, Jon Turvey, Conor Tweed, David Tweed, Rebecca Twemlow, Emma Twohey, Bhavya Tyagi, Vedang Tyagi, Abigail Tyer, Jayne Tyler, Jennifer Tyler, Alison Tyzack, Petros Tzavaras, Mohammad S Uddin, Ruhama Uddin, Ruzena Uddin, Salamat Ullah, Sana Ullah, Sanda Ullah, Athavan Umaipalan, Judith Umeadi, Akudo Umeh, Wilfred Umeojiako, Ben Ummat, Charlotte Underwood, Jonathan Underwood, Laura Unitt, Adam Unsworth, Jasvinder Uppal, Veerpal S Uppal, James Uprichard, Gerry Upson, Masood Ur Rasool, Alison Uriel, Sebastian Urruela, Hiromi Uru, Miranda Usher, Rebecca Usher, Alex UsherRea, Andrew Ustianowski, Jane Uttley, Linda C Vaccari, Uddhav Vaghela, Abhay Vaidya, Bernardas Valecka, Jennifer Valentine, Balan Valeria, Pramodh Vallabhaneni, Pedro Valle Vallines, Luke Vamplew, Ekaterini Vamvakiti, Joannis Vamvakopoulos, Maud van de Venne, Alex van der Meer, Nora van der Stelt, Joseph Vance-Daniel, Rama Vancheeswaran, Caryn Vander Riet, Samuel I Vandeyoon, Padma Vankayalapati, Piyush Vanmali, Chloe Vansomeren, William Van't Hoff, Sejal Vara, Kate Vardigans, Stehen J Vardy, Anu Varghese, Maria Varghese, William Varney, Giulia Varnier, Valeria Vasadi, Olivia Vass, Vimal Vasu, Vasanthi Vasudevan, Manu Vatish, Heloyes Vayalaman, Christopher Vaz, Niki Veale, Sachuda Veerasamy, Bar Velan, Swati Velankar, Luxmi Velauthar, Neyme Veli, Nicola Vella, Anitha Velusamy, Ian Venables, Mavi Venditti, David Veniard, Ramya Venkataramakrishnan, Richard Venn, Robert Venn, Lyn Ventilacion, Joanne Vere, Mark Veres, Stefania Vergnano, Will Verling, Amit Verma, Rachel Vernall, Britney Vernon, Mark Vertue, Jerik Verula, Natalie Vethanayagam, Lucy Veys, Carinna Vickers, Saji Victor, Jennifer Vidler, Wayne Vietri, Bavithra Vijayakumar, Vinod Warrier Vijayaraghavan Nalini, Brigita Vilcinskaite, Neringa Vilimiene, Sudharkar Vimalanathan, Lynn Vinall, Sylvia Vinay, Latha Vinayakarao, Rachel Vincent, Rosie Vincent, Pritpal Virdee, Emma Virgilio, Abdullah M Virk, Elisa Visentin, Jeyakumar Visuvanathan, Karunakaran Vithian, Sorice Vittoria, Elena Vlad, Ben Vlies, Alain Vuylsteke, Eleftheria Vyras, Richard Wach, Beverley Wadams, Susan Wadd, Natalia Waddington, Kirsten Wadsworth, Syed EI Wafa, Daniel Wagstaff, Lynda Wagstaff, Dalia Wahab, Zaroug Wahbi, Abiodun Waheed Adigun, Sawan Waidyanatha, Rachel Wake, Alice Wakefield, William Wakeford, Michelle Wakelin, Fiona Wakinshaw, Andrew Walden, Jane Walden, Lorna Walding, Alexandria Waldron, Gemma Walker, Harriet Walker, Ian Walker, Jasmine Walker, Kevin Walker, Kim Walker, Linda Walker, Marie T Walker, Olivia Walker, Rachel Walker, Rebecca Walker, Susan Walker, Derek Wallbank, Rebecca Wallbutton, Jessica Wallen, Karl Wallendszus, Arabella Waller, Fiona Waller, Rosemary Waller, Gabiel Wallis, Gabriel Wallis, Louise Wallis, Donna Walsh, Elizabeth Walsh, Livia Walsh, Deborah Walstow, Daniel Walter, Alex Walters, Holt Walters, James Walters, Jocelyn Walters, Eileen Walton, Lucy Walton, Olivia Walton, Sharon Walton, Susan Walton, Mandy Wan, Thin Wan, Mary Wands, Rachel Wane, Frank Wang, Nick Wang, Ran Wang, Deborah Warbrick, Samantha Warburton, Deborah Ward, Emma Ward, Joanna Ward, Karen Ward, Luke Ward, Nicola Ward, Rachael Ward, Rebecca Ward, Thomas Ward, Tom Ward, Scott A Warden, Adele Wardle, Karen Wardle, Steve Wardle, Hassan Wardy, Scott Waring, Jenny Warmington, Ben Warner, Christian Warner, Lewis Warnock, Sarah Warran, Jade Warren, Lisa Warren, Yolanda Warren, Hannah Warren-Miell, Gill Warwick, Charlotte Washington, Helen Wassall, Hazel J Watchorn, Holly Waterfall, Abby Waters, Donald Waters, Mark Waterstone, Catherine Watkins, Catrin Watkins, Eleanor Watkins, Karen Watkins, Lynn Watkins, Nick Watkins, Abigail Watson, Adam JR Watson, Ekaterina Watson, Eleanor Watson, Paul Watson, Rebecca Watson, Robert Watson, Sandra Watson, Malcolm Watters, Donna Watterson, Daniel Watts, John Watts, Merlin Watts, Victoria Waugh, Emma Wayman, Akhlaq Wazir, Mark Weatherhead, Nick Weatherly, Paul Weaver, Hayley Webb, Kathryn Webb, Kylie Webb, Stephen Webb, Cheryl Websdale, Deborah Webster, Ian Webster, Tim Webster, Kathleen Wedgeworth, Ling Wee, Rebecca Weerakoon, Thanuja Weerasinghe, Janaka Weeratunga, Maria Weetman, Shuying Wei, Immo Weichert, Hugh Welch, James Welch, Leanne Welch, Steven Welch, Samantha Weller, Lucy Wellings, Brian Wells, Susan Wellstead, Berni Welsh, Richard Welsh, Ingeborg Welters, Rachael Welton, Lauren Wentworth, Kate Wesseldine, James Wesson, Jim Wesson, Adam West, Magdelena West, Raha West, Ruth West, Sophie West, Luke Western, Ruth Westhead, Heather Weston, Alice Westwood, Bill Wetherill, Sharon Wheaver, Helen Wheeler, Ben Whelan, Matthew Whelband, Amanda Whileman, Alison Whitcher, Abbie White, Andrew White, Benjamin White, Christopher White, Duncan White, Emily White, James White, Jonathan White, Katie White, Marie White, Nick White, Sarah White, Sonia White, Stephen White, Tracey White, Catherine Whitehead, Anne Whitehouse, Claire Whitehouse, Tony Whitehouse, Julia Whiteley, Sophie Whiteley, Victoria Whiteside, Drew Whitley, Kaitlyn Whitley, Gabriel Whitlingum, David Whitmore, Elizabeth Whittaker, Lindsay Whittam, Andrew Whittingham Hirst, Ashley Whittington, Helen Whittle, Robert Whittle, Suzanne Whyte, Eunice Wiafe, Lou Wiblin, John Widdrington, Jason Wieboldt, Hannah Wieringa, Cornelia Wiesender, Laura Wiffen, Andrew Wight, Christopher Wignall, Danielle Wilcock, Emma Wilcock, Louise Wilcox, Laura Wild, Stephen Wild, Michael Wilde, Peter Wilding, Ritchie Wildman, Tracey Wildsmith, Joe Wileman, Donna Wiles, Joy Wiles, Kate Wiles, Elva Wilhelmsen, Thomas Wiliams, Chloe Wilkes, Janet Wilkie, David Wilkin, Hannah Wilkins, Joy Wilkins, Suzanne Wilkins, Helen Wilkinson, Holly Wilkinson, Iain Wilkinson, Lesley Wilkinson, Martin Wilkinson, Nicola Wilkinson, Sophia Wilkinson, Susan Wilkinson, Tim Wilkinson, Sylvia Willetts, Aimee Williams, Alexandra Williams, Alison Williams, Angharad Williams, Ava Williams, Carl Williams, Caroline V Williams, Claire Williams, Dewi Williams, Gail Williams, Gemma Williams, Gina Williams, Hannah Williams, James Williams, Jayne Williams, Jennie Williams, John Williams, Joseph Williams, Karen Williams, Kathryn Williams, Marie Williams, Matthew Williams, Patricia Williams, Penny Williams, Rachael Williams, Rupert Williams, Samson Williams, Sarah Williams, Sophie Williams, Tamanna Williams, Annie Williamson, Cath Williamson, Catherine Williamson, Dawn Williamson, James D Williamson, Rachel Williamson, Helen Williamson, Bruce Willian, Elizabeth Willis, Emily Willis, Heather Willis, Herika Willis, Joanna Willis, Laura Willmott, Louise Wills, Lucy Willsher, Catherine Willshire, Francesca Willson, Alison Wilson, Andrea Wilson, Antoinette Wilson, Billy Wilson, Catherine Wilson, Eve Wilson, James Wilson, Karen Wilson, Kate Wilson, Lucinda Wilson, Mark Wilson, Matthew Wilson, Toni Wilson, Evie Wiltsher, Marlar Win, Tin Win, Wut Yee Win Win, Lucinda Winckworth, Laura Winder, Piers Winder, Phillip Windrum, Kerry Winham-Whyte, Helen Winmill, Simon Winn, Carmen Winpenny, Helen Winslow, Helen Winter, Jonathan Winter, Pascal Winter, Barbara Winter-Goodwin, Stephen Wisdom, Matthew Wise, Martin Wiselka, Rebecca Wiseman, Sophie Wiseman, Steven Wishart, Holly Wissett, Eric Witele, Nicholas Withers, Janet Wittes, Donna Wixted, Therese Wodehouse, Will Wolf, Nicola Wolff, Kirsten Wolffsohn, Rebecca Wolf-Roberts, Magda Wolna, Elena Wolodimeroff, Adam Wolstencroft, Alan Wong, Charlotte Wong, Chi-Hung Wong, Edwin Wong, Jessica Sue Yi Wong, Kit Y Wong, Lee Wong, Mei Yin Wong, Nick Wong, Sam Wong, Yun Man Wong, Amanda Wood, Caroline Wood, Carrie Anne Wood, Dianne Wood, Fiona Wood, Hannah Wood, Jennifer Wood, Joe Wood, Julia Wood, Kathryn Wood, Lisa Wood, Louise Wood, Michelle Wood, Stephen Wood, Tracy Wood, Ursula Wood, Katharine Woodall, Rebecca Woodfield, Christopher Woodford, Elizabeth Woodford, Jill Woodford, Luke Woodford, Louise Woodhead, Timothy Woodhead, Philip Woodland, Marc Woodman, Debra Woods, Jane Woods, Katherine Woods, Sarah Woods, Zoe Woodward, Rachel Wookey, Megan Woolcock, Gemma Wooldridge, Rebecca Woolf, Chris Woollard, Christopher Woollard, Louisa Woollen, Emma Woolley, Jade Woolley, Daniel Woosey, Dan Wootton, Joanne Wootton, Daniel Worley, Stephy Worton, Jonathan Wraight, Maria Wray, Tim Wreford-Bush, Joanne Wren, Kim Wren, Lynn Wren, Caroline Wrey Brown, Catherine Wright, Demi Wright, Francesca Wright, Imogen Wright, Lee Wright, Lianne Wright, Pete Wright, Rachel Wright, Rebecca Wright, Stephanie Wright, Tim Wright, Caroline Wroe, Hannah Wroe, Henry Wu, Peishan Wu, Pensee Wu, Jonathan Wubetu, Retno Wulandari, Craig Wyatt, Frederick Wyn-Griffiths, Inez Wynter, Bindhu Xavier, Arnold Xhikola, Zhongyang Xia, Huiyuan Xiao, Masseh Yakubi, May Yan, Freda Yang, Yingjia Yang, Michael Yanney, Woei Lin Yap, Nabil Yaqoob, Naairah Yaqub, Salima Yasmin, Bryan Yates, David Yates, Edward Yates, Helen Yates, Julie Yates, Mark Yates, Charlotte Yearwood Martin, Andrew Yeatman, Khin Yein, Fiona Yelnoorkar, Peter Yew, Kawai Yip, Laura Ylquimiche, Laura Ylquimiche Melly, Inez Ynter, H Yong, Jemma Yorke, Jasmine Youens, Abdel Younes Ibrahim, Eoin Young, Gail Young, Louise Young, Richard Young, Asfand Yousafzar, Sajeda Youssouf, Ahmed Yousuf, Chrissie Yu, Bernard Yung, Daniel Yusef, Said Yusef, Intekhab Yusuf, Anna-Sophia Zafar, Silvia Zagalo, Su Zaher, Aqsa Zahoor, Kareem Zaki, Nabhan Zakir, Kasia Zalewska, Ane Zamalloa, Mohsin Zaman, Raisa Zaman, Shakir Zaman, Julie Zamikula, Louise Zammit, Marie Zammit-Mangion, Lynn Zarb, Esther Zebracki, Daniel Zehnder, Lisa Zeidan, Marian Zelman, Xiaobei Zhao, Dongling Zheng, Doreen Zhu, Madiha Zia, Omar Zibdeh, Rabia Zill-E-Huma, Ei Thankt Zin, Veronica Zindonda, Eleanor Zinkin, Vivian Zinyemba, Christos Zipitis, Arkadiusz Zmierczak, Azam Zubir, Roslin Zuha, Naz Zuhra, Rasha Zulaikha, Sabrina Zulfikar, Carol Zullo, Ana Zuriaga-Alvaro, Will Zuurbier, Sheba Zyengi, and University of St Andrews. School of Medicine
Subjects: Male, Convalescent plasma, medicine.medical_treatment, 030204 cardiovascular system & hematology, Antibodies, Viral, Rate ratio, 0302 clinical medicine, RA0421, RA0421 Public health. Hygiene. Preventive Medicine, Medicine, Hospital Mortality, 030212 general & internal medicine, 11 Medical and Health Sciences, Aged, 80 and over, Medicine(all), Mortality rate, Covid19, Articles, 3rd-DAS, General Medicine, Middle Aged, Hospitals, Treatment Outcome, Female, Open label, Coronavirus Infections, Life Sciences & Biomedicine, RM, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), 03 medical and health sciences, Medicine, General & Internal, SDG 3 - Good Health and Well-being, General & Internal Medicine, Internal medicine, Humans, In patient, Pandemics, COVID-19 Serotherapy, Aged, Mechanical ventilation, Science & Technology, SARS-CoV-2, business.industry, Significant difference, Immunization, Passive, COVID-19, Length of Stay, NIS, R1, Respiration, Artificial, United Kingdom, RM Therapeutics. Pharmacology, RECOVERY Collaborative Group, business
Abstract: Background: Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19. Methods: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. The trial is underway at 177 NHS hospitals from across the UK. Eligible and consenting patients were randomly assigned (1:1) to receive either usual care alone (usual care group) or usual care plus high-titre convalescent plasma (convalescent plasma group). The primary outcome was 28-day mortality, analysed on an intention-to-treat basis. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936. Findings: Between May 28, 2020, and Jan 15, 2021, 11558 (71%) of 16287 patients enrolled in RECOVERY were eligible to receive convalescent plasma and were assigned to either the convalescent plasma group or the usual care group. There was no significant difference in 28-day mortality between the two groups: 1399 (24%) of 5795 patients in the convalescent plasma group and 1408 (24%) of 5763 patients in the usual care group died within 28 days (rate ratio 1·00, 95% CI 0·93–1·07; p=0·95). The 28-day mortality rate ratio was similar in all prespecified subgroups of patients, including in those patients without detectable SARS-CoV-2 antibodies at randomisation. Allocation to convalescent plasma had no significant effect on the proportion of patients discharged from hospital within 28 days (3832 [66%] patients in the convalescent plasma group vs 3822 [66%] patients in the usual care group; rate ratio 0·99, 95% CI 0·94–1·03; p=0·57). Among those not on invasive mechanical ventilation at randomisation, there was no significant difference in the proportion of patients meeting the composite endpoint of progression to invasive mechanical ventilation or death (1568 [29%] of 5493 patients in the convalescent plasma group vs 1568 [29%] of 5448 patients in the usual care group; rate ratio 0·99, 95% CI 0·93–1·05; p=0·79). Interpretation: In patients hospitalised with COVID-19, high-titre convalescent plasma did not improve survival or other prespecified clinical outcomes. Funding: UK Research and Innovation (Medical Research Council) and National Institute of Health Research.
Published: 2021

9. Abstract PS7-59: Presence of comorbidities and use of concomitant medications associated with QTC prolongation/torsades de pointes in patients with HR+/HER2- advanced breast cancer

Author: Reshma Mahtani, Katie Lewis, Emily Clayton, Matthew Last, Debanjali Mitra, and Samantha Kurosky
Subjects: Cancer Research, medicine.medical_specialty, education.field_of_study, business.industry, Population, Torsades de pointes, medicine.disease, Metastatic breast cancer, QT interval, Comorbidity, Breast cancer, Oncology, Concomitant, Internal medicine, medicine, Risk factor, education, business
Abstract: BACKGROUND: Corrected QT (QTc) prolongation is a cardiac condition that may increase the risk of ventricular arrhythmias, including Torsades de Pointes (TdP), and cardiac-related death. QTc prolongation is a notable concern in oncology as drug-induced QTc prolongation is a documented side effect of several anticancer therapies. Moreover, patient-specific risk factors for QTc prolongation such as increased age and a history of cardiovascular disease/events can be common among patients with metastatic breast cancer, which puts this population at an increased baseline risk for QTc prolongation. Female sex is a risk factor itself. The objective of this study was to characterize the presence of comorbidities and use of concomitant medications associated with QTc prolongation/TdP among patients receiving first-line (1L) treatment for HR+/HER2- locally advanced or metastatic breast cancer (aBC).METHODS: Oncologists in France, Germany, Israel, Italy, Spain and the United States abstracted clinical characteristics and medication data from the medical records of patients, aged ≥18, who received 1L treatment for HR+/HER2- aBC between 10/2019 and 02/2020. The presence of comorbidities (e.g., congestive heart failure, myocardial infarction, history of atrial arrythmias) and utilization of concomitant medications (excluding anti-cancer therapies) with known, possible, or conditional risk for QTc prolongation/TdP were summarized. The list of comorbidity risk factors was compiled from a targeted literature search and clinician review. The list of concomitant medications was obtained from crediblemeds.org.RESULTS: A total of 1164 patients with aBC were sampled across the six countries. Among them, 99% were female and the mean age was 62 years. The majority of patients had metastatic disease (85%); 15% had locally advanced disease. Among those with metastatic disease, 47% had visceral metastasis and 34% had bone-only metastasis. At 1L initiation, 84% of patients had an ECOG score of 0/1. Comorbidities associated with risk of QTc prolongation/TdP were observed in 8% of patients; the most frequently observed were congestive heart failure (3%) and history of myocardial infarction (2%) (Table 1). The proportion of patients who received at least one medication associated with risk of QTc prolongation/TdP was 39%. Overall, 42% of patients had at least one comorbidity or medication associated with risk of QTc prolongation/TdP. CONCLUSIONS: Approximately 2 out of 5 patients receiving 1L treatment for HR+/HER2- aBC had a comorbidity or utilized a concomitant medication that could increase risk of QTc prolongation/TdP. As cardiovascular toxicity is a known side effect associated with several anticancer therapies, the high prevalence of coexisting risk factors among patients receiving 1L treatment underscores the importance of assessing patients’ existing risk when selecting treatments for advanced breast cancer. Table 1. Presence of Comorbidities and Use of Concomitant Medications with known, possible, or conditional risk for QTc prolongation/TdP in Patients Who Received First-Line Therapy for HR+/HER2- Advanced Breast CancerN%Total Patients1164100ComorbiditiesMyocardial infarction202Congestive heart failure323Moderate or severe liver disease3 Citation Format: Reshma Mahtani, Katie Lewis, Emily Clayton, Matthew Last, Debanjali Mitra, Samantha Kurosky. Presence of comorbidities and use of concomitant medications associated with QTC prolongation/torsades de pointes in patients with HR+/HER2- advanced breast cancer [abstract]. In: Proceedings of the 2020 San Antonio Breast Cancer Virtual Symposium; 2020 Dec 8-11; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2021;81(4 Suppl):Abstract nr PS7-59.
Published: 2021

10. Collaborative Multinational Military Education: Arctic Simulation

Author: David Last, Carsten F. Roennfeldt, and Brytan Mendes
Subjects: International relations, experiential learning, lcsh:Military Science, business.industry, lcsh:U, international relations, Cross-cultural communication, Organizational culture, professional military education, General Medicine, Public relations, simulation, Experiential learning, Problem-based learning, Multinational corporation, cross-cultural communication, Political science, problem-based learning, business, Competence (human resources), Educational program
Abstract: This article presents an on-line simulation exercise for cadets at military colleges in Canada, Norway, and the United States in 2019. The pilot project aspired to learn whether it is possible within a normal professional military educational program to gain cross-cultural and international relations competence by creating peer-to-peer contact between cadets on digital platforms. Working across language and cultural barriers in an international environment is a valuable professional skill, but military academies face constraints of regulation, cost, scheduling, and organizational culture which can preclude multinational simulations, however valuable these might be. This article describes the background research and preparations, method of execution, constraints on the conduct of the pilot project, considerations for future events, and advantages or learning opportunities identified in running the pilot. It concludes with suggestions for future military peer-to-peer simulations.
Published: 2021

11. Penalty term based suitable fuzzy intuitionistic possibilistic clustering: analyzing high dimensional gene expression cancer database

Author: S. R. Kannan, Esha Kashyap, Mark Last, and Tzung-Pei Hong
Subjects: 0209 industrial biotechnology, Ground truth, business.industry, Computer science, Pattern recognition, Computational intelligence, 02 engineering and technology, High dimensional, Fuzzy logic, Theoretical Computer Science, Term (time), ComputingMethodologies_PATTERNRECOGNITION, 020901 industrial engineering & automation, Kernel (statistics), 0202 electrical engineering, electronic engineering, information engineering, 020201 artificial intelligence & image processing, Geometry and Topology, Artificial intelligence, Cluster analysis, business, Software
Abstract: The aim of this paper is to identify the co-expressed potential genes that may serve for the development of the portions of normal or tumor. This paper differentiates the co-expressed genes into normal samples and tumor samples from gene expression dataset GSE25066. Since the dataset has vague boundaries and having common characteristics between the clusters, identifying the subgroups contain similar gene expression is really a tricky task one. Therefore, this paper introduces an effective fuzzy iterative clustering algorithm by incorporating kernel function, possibilistic c-means, fuzzy memberships, neighborhood information, median of neighboring objects and penalty term. The performances of the proposed clustering techniques have been shown through the succession experimental works on GSE25066. The effects of clustering results have been proved through comparing the resulted classes with ground truth.
Published: 2020

12. Anti‐racist learning and teaching in British geography

Author: Angela Last and James Esson
Subjects: Praxis, Guiding Principles, Higher education, business.industry, Anti-racism, media_common.quotation_subject, Geography, Planning and Development, Context (language use), Racism, Pedagogy, business, Discipline, Curriculum, media_common
Abstract: This special section illustrates how learning and teaching in UK higher education reinforces, but can potentially also help to counteract, racism. This introduction provides some context for this intervention and provides an outline of key themes that emerge from the collection of papers. We use these themes to sketch out three guiding principles for the incorporation of explicitly anti-racist praxis in our learning and teaching within British Geography 1) Recognise each other’s humanity 2) Say the unsayable 3) Experiment with (y)our history. We call for explicitly anti-racist praxis while conscious of the ‘disciplinary fragility’ that moves to address racism might elicit. It is argued that an anti-racist approach to learning and teaching in British Geography has the potential to equip staff and students with the tools to help make our discipline, and wider society, more equitable and just.
Published: 2020

13. The Airwaves Belong to the People: A Critical Analysis of Radio Broadcasting and Licensing in Zimbabwe

Author: Last Alfandika and Gift Gwindingwe
Subjects: Government, business.industry, Communication, media_common.quotation_subject, 05 social sciences, Media studies, Sincerity, 050801 communication & media studies, Broadcasting, Democracy, Public interest, 0508 media and communications, Pluralism (political theory), Political science, 0502 economics and business, 050211 marketing, business, Radio broadcasting, Diversity (politics), media_common
Abstract: This article reports on a study that focused on the radio broadcasting and licensing scene in Zimbabwe between 2000 and 2020. The study interrogated the sincerity of the Zimbabwean government in ad...
Published: 2020

14. Long‐term outcomes of patients with conserved breast cancer treated with adjuvant hypofractionated prone breast intensity‐modulated radiation therapy

Author: Aron M Gortman, Noel J Aherne, Julan Amalaseelan, Andrew Last, Justin Westhuyzen, Lauren Chamberlain, and Thomas P Shakespeare
Subjects: medicine.medical_specialty, Supine position, medicine.medical_treatment, Breast pain, Breast Neoplasms, Mastectomy, Segmental, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, medicine, Humans, Radiology, Nuclear Medicine and imaging, Breast, Pneumonitis, Chemotherapy, business.industry, Cosmesis, Middle Aged, medicine.disease, Radiation therapy, Prone position, Oncology, 030220 oncology & carcinogenesis, Female, Radiation Dose Hypofractionation, Radiotherapy, Intensity-Modulated, Radiology, Neoplasm Recurrence, Local, medicine.symptom, business
Abstract: Introduction New techniques for adjuvant radiation therapy after breast conservation include prone positioning, hypofractionation and intensity-modulated radiation therapy (IMRT). Long-term evaluations of this combination are lacking, and we report our own experience. Methods Patients with invasive breast cancer followed for a minimum 36 months post-IMRT were eligible. Dose used was 40 Gray in 15 fractions over 3 weeks to the whole breast via forward-planned prone, whole breast IMRT. A 10 Gy in 5 fraction supine boost was offered. Results Between January 2012 and January 2020, 2199 patients had breast conservation and adjuvant radiation: 489 received hypofractionated prone breast IMRT, with 155 eligible for our evaluation. Median follow-up was 52 months. Median age was 62 (range 36-80), 78.7% were T1, 20.6% were T2, and 12.3% were node-positive. Grade was 1 in 26.5%, 2 in 43.9% and 3 in 29.7%; 87.1% were oestrogen receptor positive, 3.2% were HER2 positive, and 11.0% were triple negative. 58.6% received a boost, 74.8% endocrine therapy and 32.3% chemotherapy. No patient developed local recurrence. One regional recurrence was successfully salvaged. Six patients (3.9%) developed metastases, and 1.9% died. Five-year actuarial local recurrence-free, regional recurrence-free and breast cancer-specific survival rates were 100.0%, 98.2% and 94.8%. Late grade 1 and 2 breast pain occurred in 20.0% and 1.3% of patients. Only 11.0% had new pain compared to pre-radiation. No patient developed radiation-induced pneumonitis, pulmonary fibrosis, rib fracture or cardiac toxicity. All patients scored cosmesis as 'good' or better. Conclusion Adjuvant hypofractionated prone breast IMRT has excellent locoregional control and minimal toxicity.
Published: 2020

15. Prevalence of and risk factors for curable sexually transmitted infections on Bubaque Island, Guinea Bissau

Author: Giovanna Cowley, Gregory Milne, Eunice Teixeira da Silva, Jose Nakutum, Amabelia Rodrigues, Hristina Vasileva, David Mabey, Bart Versteeg, and Anna Last
Subjects: Male, Epidemiology, Chlamydia trachomatis, Mycoplasma genitalium, Logistic regression, medicine.disease_cause, urologic and male genital diseases, Gonorrhea, 0302 clinical medicine, Risk Factors, Prevalence, Medicine, Guinea-Bissau, 030212 general & internal medicine, education.field_of_study, biology, Transmission (medicine), Middle Aged, female genital diseases and pregnancy complications, 3. Good health, Infectious Diseases, Female, 0305 other medical science, Trichomonas Vaginitis, Adult, Adolescent, Population, Protective factor, Sexually Transmitted Diseases, Dermatology, 03 medical and health sciences, Young Adult, Trichomonas vaginalis, Humans, Mycoplasma Infections, Syphilis, Treponema pallidum, education, epidemiology (general), 030505 public health, business.industry, genital tract infection, DNA, Chlamydia Infections, biology.organism_classification, Neisseria gonorrhoeae, Cross-Sectional Studies, Guinea bissau, Africa, business, Demography
Abstract: ObjectivesComplications from sexually transmitted infections (STIs) can result in severe morbidity and mortality. To date, no STI population studies have been conducted on the Bijagos Islands, Guinea Bissau. Our objective was to estimate the prevalence of and identify risk factors for Chlamydia trachomatis (Ct), Neisseria gonorrhoea (Ng), Mycoplasma genitalium (Mg), Trichomonas vaginalis (Tv) and Treponema pallidum (Tp) on Bubaque, the most populated island.MethodsA cross-sectional survey was conducted on the island of Bubaque among people aged 16–49 years. Participants were asked to answer a questionnaire on STI risk factors, to provide urine samples (men and women) and vaginal swabs (women) for PCR testing for Ct, Ng, Mg and Tv, and to provide dry blood spots for Tp particle agglutination assays. Data were analysed to estimate the prevalence of STIs and logistic regression was used to identify risk factors.ResultsIn total, 14.9% of participants were found to have a curable STI, with the highest prevalence being observed for Tv (5.9%) followed by Ct (3.8%), Ng (3.8%), Mg (1.9%) and Tp (0.8%). Significant risk factors for having any STI included being female, younger age and concurrent partnership. Having had a previous STI that was optimally treated was a protective factor.ConclusionsThis study demonstrates that there is a considerable burden of STI on the Bijagos Islands, stressing the need for diagnostic testing to facilitate early detection and treatment of these pathogens to stop ongoing transmission. Moreover, these results indicate the need to conduct further research into the STI burden on the Bijagos Islands to help inform and develop a national STI control strategy.
Published: 2020

16. How does small group continuing medical education (CME) impact on practice for rural GPs and their patients, a mixed-methods study

Author: Stephanie Dowling, J Last, H Finnegan, John Bourke, Pat Daly, Conor Hanrahan, Pat Harrold, Geoff McCoombe, and W Cullen
Subjects: Male, Rural Population, medicine.medical_specialty, 020205 medical informatics, education, Psychological intervention, Inappropriate Prescribing, 02 engineering and technology, Audit, 03 medical and health sciences, Deprescriptions, 0302 clinical medicine, Continuing medical education, General Practitioners, Surveys and Questionnaires, 0202 electrical engineering, electronic engineering, information engineering, medicine, Humans, Learning, 030212 general & internal medicine, TUTOR, Aged, computer.programming_language, Clinical Audit, business.industry, Focus Groups, Focus group, Family medicine, Small group learning, Global Positioning System, Education, Medical, Continuing, Female, Deprescribing, Family Practice, business, Ireland, computer
Abstract: Studies which report outcomes of continuing medical education (CME) interventions for rural general practitioners (GPs) are limited. This mixed methods study recruited GPs from four CME small group learning (SGL) tutor groups based in different rural locations in the Republic of Ireland. A two-hour teaching module on deprescribing in older patients was devised and implemented. Assessment of educational outcomes was via questionnaires, prescribing audits and qualitative focus groups. All GPs (n = 43) in these CME-SGL groups agreed to participate, 27 of whom (63%) self-identified as being in rural practice. Rural GPs were more likely to be male (56%), in practice for longer (19 years), and attending CME for longer (13 years). The questionnaires indicated learning outcomes were achieved knowledge increased immediately after the education, and was maintained 6 months later. Twenty-four GPs completed audits involving 191 patients. Of these, 152 (79.6%) were de-prescribed medication. In the qualitative focus groups, GPs reported sharing experiences with their peers during CME-SGL helped them to improve patient care and ensured that clinical practice is more consistent across the group. For rural GPs, CME-SGL involving discussion of cases and the practical implementation of guidelines, associated with audit, can lead to changes in patient care.
Published: 2020

17. An unsupervised constrained optimization approach to compressive summarization

Author: Natalia Vanetik, Marina Litvak, Elena Churkin, and Mark Last
Subjects: Information Systems and Management, Computer science, 02 engineering and technology, computer.software_genre, Theoretical Computer Science, Artificial Intelligence, 0202 electrical engineering, electronic engineering, information engineering, Time complexity, Parsing, business.industry, 05 social sciences, Parse tree, Constrained optimization, 050301 education, Automatic summarization, Computer Science Applications, Tree (data structure), Control and Systems Engineering, 020201 artificial intelligence & image processing, Node (circuits), Artificial intelligence, business, 0503 education, computer, Software, Natural language processing
Abstract: Automatic summarization is typically aimed at selecting as much information as possible from text documents using a predefined number of words. Extracting complete sentences into a summary is not an optimal way to solve this problem due to redundant information that is contained in some sentences. Removing the redundant information and compiling a summary from compressed sentences should provide a much more accurate result. Major challenges of compressive approaches include the cost of creating large summarization corpora for training the supervised methods, the linguistic quality of compressed sentences, the coverage of the relevant content, and the time complexity of the compression procedure. In this work, we attempt to address these challenges by proposing an unsupervised polynomial-time compressive summarization algorithm. The proposed algorithm iteratively removes redundant parts from original sentences. It uses constituency-based parse trees and hand-crafted rules for generating elementary discourse units (EDUs) from their subtrees (standing for phrases) and selects ones with a sufficient tree gain. We define a parse tree gain as a weighted function of its node weights, which can be computed by any extractive summarization model capable of assigning importance weights to terms. The results of automatic evaluations on a single-document summarization task confirm that the proposed sentence compression procedure helps to avoid redundant information in the generated summaries. Furthermore, the results of human evaluations confirm that the linguistic quality—in terms of readability and coherency—is preserved in the compressed summaries while improving their coverage. However, the same evaluations show that compression in general harms the grammatical correctness of compressed sentences though, in most cases, this effect is not significant for the proposed compression procedure.
Published: 2020

18. Pharmacokinetics of Direct Oral Anticoagulants in Emergency Situations: Results of the Prospective Observational RADOA-Registry

Author: Jan Beyer-Westendorf, Ariane Sümnig, Ulrike Nowak-Göttl, Sebastian Schellong, Simone Lindau, Patrick Meybohm, Ingvild Birschmann, Eva Herrmann, Christian von Heymann, Jessica Lucks, Joachim Kuhn, Andreas Greinacher, Oliver Grottke, Edelgard Lindhoff-Last, Barbara Zydek, and Stavros Konstantinides
Subjects: medicine.medical_specialty, medicine.drug_class, Pyridones, Administration, Oral, Hemorrhage, Pharmacokinetics, Rivaroxaban, Internal medicine, Atrial Fibrillation, medicine, Humans, Prospective Studies, Registries, business.industry, Anticoagulant, Anticoagulants, Hematology, Emergency situations, Confidence interval, Dabigatran, Clinical trial, Apixaban, Observational study, business, medicine.drug
Abstract: Thrombosis and haemostasis 122(4), 552-559 (2022). doi:10.1055/a-1549-6556, Published by Thieme, Stuttgart
Published: 2022

19. Staircase array of inclined refractive multi‐lenses for large field of view pixel super‐resolution scanning transmission hard X‐ray microscopy

Author: Talgat Mamyrbayev, Katsumasa Ikematsu, Hidekazu Takano, Yanlin Wu, Kenji Kimura, Patrick Doll, Arndt Last, Atsushi Momose, Pascal Meyer, Mamyrbayev, Talgat, 1Institute of Microstructure Technology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344Eggenstein-Leopoldshafen, Baden-Württemberg, Germany, Ikematsu, Katsumasa, 2Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi980-8577, Japan, Takano, Hidekazu, Wu, Yanlin, Kimura, Kenji, Doll, Patrick, Last, Arndt, and Momose, Atsushi
Subjects: Nuclear and High Energy Physics, Materials science, Photon, EBL, deep X‐ray lithography and electroplating, scanning transmission hard X-ray microscopy, deep X-ray lithography and electroplating, Synchrotron radiation, Field of view, pixel super-resolution, scanning transmission hard X‐ray microscopy, 02 engineering and technology, XRL, 01 natural sciences, inclined refractive X-ray multi-lens array, law.invention, 010309 optics, Optics, law, Technologien DLW, 0103 physical sciences, Microscopy, 502.82, Proposal 2017-019-020309, pixel super‐resolution, Instrumentation, Image resolution, Lithography, Engineering & allied operations, inclined refractive X‐ray multi‐lens array, Radiation, business.industry, Detector, 021001 nanoscience & nanotechnology, Research Papers, Synchrotron, ddc:620, 0210 nano-technology, business
Abstract: Owing to the development of X‐ray focusing optics during the past decades, synchrotron‐based X‐ray microscopy techniques allow the study of specimens with unprecedented spatial resolution, down to 10 nm, using soft and medium X‐ray photon energies, though at the expense of the field of view (FOV). One of the approaches to increase the FOV to square millimetres is raster‐scanning of the specimen using a single nanoprobe; however, this results in a long data acquisition time. This work employs an array of inclined biconcave parabolic refractive multi‐lenses (RMLs), fabricated by deep X‐ray lithography and electroplating to generate a large number of long X‐ray foci. Since the FOV is limited by the pattern height if a single RML is used by impinging X‐rays parallel to the substrate, many RMLs at regular intervals in the orthogonal direction were fabricated by tilted exposure. By inclining the substrate correspondingly to the tilted exposure, 378000 X‐ray line foci were generated with a length in the centimetre range and constant intervals in the sub‐micrometre range. The capability of this new X‐ray focusing device was first confirmed using ray‐tracing simulations and then using synchrotron radiation at BL20B2 of SPring‐8, Japan. Taking account of the fact that the refractive lens is effective for focusing high‐energy X‐rays, the experiment was performed with 35 keV X‐rays. Next, by scanning a specimen through the line foci, this device was used to perform large FOV pixel super‐resolution scanning transmission hard X‐ray microscopy (PSR‐STHXM) with a 780 ± 40 nm spatial resolution within an FOV of 1.64 cm × 1.64 cm (limited by the detector area) and a total scanning time of 4 min. Biomedical implant abutments fabricated via selective laser melting using Ti–6Al–4V medical alloy were measured by PSR‐STHXM, suggesting its unique potential for studying extended and thick specimens. Although the super‐resolution function was realized in one dimension in this study, it can be expanded to two dimensions by aligning a pair of presented devices orthogonally., A new X‐ray focusing device generates hundreds of thousands of line foci, periodically spaced in the sub‐micrometre range, with centimetre length. It enables to achieve large FOV pixel super‐resolution scanning transmission hard X‐ray microscopy. image
Published: 2021

20. 3D-Printing Enables Fabrication of Swirl Nozzles for Fast Aerosolization of Water-Based Drugs

Author: Torben S. Last, Goran Stemme, and Niclas Roxhed
Subjects: Fabrication, Materials science, business.industry, 020209 energy, Mechanical Engineering, Inhaler, Nozzle, Analytical chemistry, 3D printing, 02 engineering and technology, Spray nozzle, 020303 mechanical engineering & transports, 0203 mechanical engineering, Cleanroom, 0202 electrical engineering, electronic engineering, information engineering, Particle, Electrical and Electronic Engineering, business, Aerosolization
Abstract: Portable inhalers are used for delivering drugs to the lung in the form of aerosols and form the standard treatment for diseases such as Asthma, COPD, and cystic fibrosis. However, for aqueous drug formulations, spray nozzle chips have so far been restricted to cleanroom manufacture due to their small feature sizes. Here we present a spring-actuated 3D-printed swirl nozzle that sprays an aqueous drug solution, matching propellant-containing inhalers in aerosolization time. The use of two-photon polymerization enables the small nozzle feature size of 100 $\mu \text{m}$ and device print times of only 4 min, making serial mass-fabrication a viable option. Our 35 bar spring-operated swirl nozzle prototype achieves mean volumetric particle sizes of 12.5 ${\mu }\text{m}$ on doses of 100 ${\mu }\text{l}$ , aerosolized in 270 ms, as fast as a propellant-driven inhaler. [2021-0002]
Published: 2021

21. Combined antibiotic stewardship and infection control measures to contain the spread of linezolid-resistant Staphylococcus epidermidis in an intensive care unit

Author: Cihan Papan, Matthias Schröder, Mathias Hoffmann, Heike Knoll, Katharina Last, Frederic Albrecht, Jürgen Geisel, Tobias Fink, Barbara C. Gärtner, Alexander Mellmann, Thomas Volk, Fabian K. Berger, and Sören L. Becker
Subjects: 0301 basic medicine, Microbiology (medical), medicine.medical_specialty, medicine.drug_class, 030106 microbiology, Antibiotics, Infection control, Infectious and parasitic diseases, RC109-216, Antimicrobial stewardship, Antimicrobial resistance, law.invention, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Antibiotic resistance, Staphylococcus epidermidis, law, Internal medicine, Germany, Drug Resistance, Bacterial, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Staphylococci, Cross Infection, Whole-genome sequencing, biology, Whole Genome Sequencing, business.industry, Research, Public Health, Environmental and Occupational Health, Linezolid, Staphylococcal Infections, biology.organism_classification, Intensive care unit, Intensive Care Units, Infectious Diseases, chemistry, Vancomycin, Daptomycin, business, medicine.drug
Abstract: BackgroundThe unrestricted use of linezolid has been linked to the emergence of linezolid-resistantStaphylococcus epidermidis(LRSE). We report the effects of combined antibiotic stewardship and infection control measures on the spread of LRSE in an intensive care unit (ICU).MethodsMicrobiological data were reviewed to identify all LRSE detected in clinical samples at an ICU in southwest Germany. Quantitative data on the use of antibiotics with Gram-positive coverage were obtained in defined daily doses (DDD) per 100 patient-days (PD). In addition to infection control measures, an antibiotic stewardship intervention was started in May 2019, focusing on linezolid restriction and promoting vancomycin, wherever needed. We compared data from the pre-intervention period (May 2018–April 2019) to the post-intervention period (May 2019–April 2020). Whole-genome sequencing (WGS) was performed to determine the genetic relatedness of LRSE isolates.ResultsIn the pre-intervention period, LRSE were isolated from 31 patients (17 in blood cultures). The average consumption of linezolid and daptomycin decreased from 7.5 DDD/100 PD and 12.3 DDD/100 PD per month in the pre-intervention period to 2.5 DDD/100 PD and 5.7 DDD/100 PD per month in the post-intervention period (p = 0.0022 and 0.0205), respectively. Conversely, vancomycin consumption increased from 0.2 DDD/100 PD per month to 4.7 DDD/100 PD per month (p ConclusionsComplementing infection control measures by targeted antibiotic stewardship interventions was beneficial in containing the spread of LRSE in an ICU.
Published: 2021
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22. Analysis of the outer divertor hot spot activity in the protection video camera recordings at JET

Author: Drenik, A., Brezinsek, S., Carvalho, P., Huber, V., Osterman, N., Matthews, G. F., Nemec, M., Litaudon, X., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Andersson Sunden, E., Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Baron Wiechec, A., Barrera Orte, L., Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Casson, F. J., Castaldo, C., Catarino, N., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chitarin, G., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clark, M., Clarkson, R., Clatworthy, D., Clements, C., Cleverly, M., Coad, J. P., Coates, P. A., Cobalt, A., Coccorese, V., Cocilovo, V., Coda, S., Coelho, R., Coenen, J. W., Coffey, I., Colas, L., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M. P., Craciunescu, T., Cramp, S., Craven, R., Crisanti, F., Croci, G., Croft, D., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarnecka, A., Dabirikhah, H., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., Davies, O., Davis, W., Day, C., Day, I. E., De Bock, M., de Castro, A., de la Cal, E., de la Luna, E., De Masi, G., de Pablos, J. L., De Temmerman, G., De Tommasi, G., de Vries, P., Deakin, K., Deane, J., Degli Agostini, F., Dejarnac, R., Delabie, E., den Harder, N., Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dinca, P., D'Inca, R., Ding, B., Dittmar, T., Doerk, H., Doerner, R. P., Donne, T., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Drewelow, P., Drews, P., Duckworth, P., Dumont, R., Dumortier, P., Dunai, D., Dunne, M., Duran, I., Durodie, F., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edmond, J., Edwards, A. M., Edwards, J., Eich, T., Ekedahl, A., El-Jorf, R., Elsmore, C. G., Enachescu, M., Ericsson, G., Eriksson, F., Eriksson, J., Eriksson, L. G., Esposito, B., Esquembri, S., Esser, H. G., Esteve, D., Evans, B., Evans, G. E., Evison, G., Ewart, G. D., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Fasoli, A., Faustin, J. M., Fawlk, N., Fazendeiro, L., Fedorczak, N., Felton, R. C., Fenton, K., Fernades, A., Fernandes, H., Ferreira, J., Fessey, J. A., Fevrier, O., Ficker, O., Field, A., Fietz, S., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Fonnesu, N., Fontdecaba, J. M., Formisano, A., Forsythe, L., Fortuna, L., Fortuna-Zalesna, E., Fortune, M., Foster, S., Franke, T., Franklin, T., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Frigione, D., Fuchs, V., Fuller, D., Futatani, S., Fyvie, J., Gal, K., Galassi, D., Galazka, K., Galdon-Quiroga, J., Gallagher, J., Gallart, D., Galvao, R., Gao, X., Gao, Y., Garcia, J., Garcia-Carrasco, A., Garcia-Munoz, M., Gardarein, J. L., Garzotti, L., Gaudio, P., Gauthier, E., Gear, D. F., Gee, S. J., Geiger, B., Gelfusa, M., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Ghate, M., Gherendi, M., Giacalone, J. C., Giacomelli, L., Gibson, C. S., Giegerich, T., Gil, C., Gil, L., Gilligan, S., Gin, D., Giovannozzi, E., Girardo, J. B., Giroud, C., Giruzzi, G., Gloeggler, S., Godwin, J., Goff, J., Gohil, P., Goloborod'Ko, V., Gomes, R., Goncalves, B., Goniche, M., Goodliffe, M., Goodyear, A., Gorini, G., Gosk, M., Goulding, R., Goussarov, A., Gowland, R., Graham, B., Graham, M. E., Graves, J. P., Grazier, N., Grazier, P., Green, N. R., Greuner, H., Grierson, B., Griph, F. S., Grisolia, C., Grist, D., Groth, M., Grove, R., Grundy, C. N., Grzonka, J., Guard, D., Guerard, C., Guillemaut, C., Guirlet, R., Gurl, C., Utoh, H. H., Hackett, L. J., Hacquin, S., Hagar, A., Hager, R., Hakola, A., Halitovs, M., Hall, S. J., Hallworth Cook, S. P., Hamlyn-Harris, C., Hammond, K., Harrington, C., Harrison, J., Harting, D., Hasenbeck, F., Hatano, Y., Hatch, D. R., Haupt, T. D. V., Hawes, J., Hawkes, N. C., Hawkins, J., Hawkins, P., Haydon, P. W., Hayter, N., Hazel, S., Heesterman, P. J. L., Heinola, K., Hellesen, C., Hellsten, T., Helou, W., Hemming, O. N., Hender, T. C., Henderson, M., Henderson, S. S., Henriques, R., Hepple, D., Hermon, G., Hertout, P., Hidalgo, C., Highcock, E. G., Hill, M., Hillairet, J., Hillesheim, J., Hillis, D., Hizanidis, K., Hjalmarsson, A., Hobirk, J., Hodille, E., Hogben, C. H. A., Hogeweij, G. M. D., Hollingsworth, A., Hollis, S., Homfray, D. A., Horacek, J., Hornung, G., Horton, A. R., Horton, L. D., Horvath, L., Hotchin, S. P., Hough, M. R., Howarth, P. J., Hubbard, A., Huber, A., Huddleston, T. M., Hughes, M., Huijsmans, G. T. A., Hunter, C. L., Huynh, P., Hynes, A. M., Iglesias, D., Imazawa, N., Imbeaux, F., Imrisek, M., Incelli, M., Innocente, P., Irishkin, M., Ivanova-Stanik, I., Jachmich, S., Jacobsen, A. S., Jacquet, P., Jansons, J., Jardin, A., Jarvinen, A., Jaulmes, F., Jednorog, S., Jenkins, I., Jeong, C., Jepu, I., Joffrin, E., Johnson, R., Johnson, T., Johnston, J., Joita, L., Jones, G., Jones, T. T. C., Hoshino, K. K., Kallenbach, A., Kamiya, K., Kaniewski, J., Kantor, A., Kappatou, A., Karhunen, J., Karkinsky, D., Karnowska, I., Kaufman, M., Kaveney, G., Kazakov, Y., Kazantzidis, V., Keeling, D. L., Keenan, T., Keep, J., Kempenaars, M., Kennedy, C., Kenny, D., Kent, J., Kent, O. N., Khilkevich, E., Kim, H. T., Kim, H. S., Kinch, A., King, C., King, D., King, R. F., Kinna, D. J., Kiptily, V., Kirk, A., Kirov, K., Kirschner, A., Kizane, G., Klepper, C., Klix, A., Knight, P., Knipe, S. J., Knott, S., Kobuchi, T., Koechl, F., Kocsis, G., Kodeli, I., Kogan, L., Kogut, D., Koivuranta, S., Kominis, Y., Koepen, M., Kos, B., Koskela, T., Koslowski, H. R., Koubiti, M., Kovari, M., Kowalska-Strzeciwilk, E., Krasilnikov, A., Krasilnikov, V., Krawczyk, N., Kresina, M., Krieger, K., Krivska, A., Kruezi, U., Ksiazek, I., Kukushkin, A., Kundu, A., Kurki-Suonio, T., Kwak, S., Kwiatkowski, R., Kwon, O. J., Laguardia, L., Lahtinen, A., Laing, A., Lam, N., Lambertz, H. T., Lane, C., Lang, P. T., Lanthaler, S., Lapins, J., Lasa, A., Last, J. R., Laszynska, E., Lawless, R., Lawson, A., Lawson, K. D., Lazaros, A., Lazzaro, E., Leddy, J., Lee, S., Lefebvre, X., Leggate, H. J., Lehmann, J., Lehnen, M., Leichtle, D., Leichuer, P., Leipold, F., Lengar, I., Lennholm, M., Lerche, E., Lescinskis, A., Lesnoj, S., Letellier, E., Leyland, M., Leysen, W., Li, L., Liang, Y., Likonen, J., Linke, J., Linsmeier, C., Lipschultz, B., Liu, G., Liu, Y., Lo Schiavo, V. P., Loarer, T., Loarte, A., Lobel, R. C., Lomanowski, B., Lomas, P. J., Lonnroth, J., Lopez, J. M., Lopez-Razola, J., Lorenzini, R., Losada, U., Lovell, J. J., Loving, A. B., Lowry, C., Luce, T., Lucock, R. M. A., Lukin, A., Luna, C., Lungaroni, M., Lungu, C. P., Lungu, M., Lunniss, A., Lupelli, I., Lyssoivan, A., Macdonald, N., Macheta, P., Maczewa, K., Magesh, B., Maget, P., Maggi, C., Maier, H., Mailloux, J., Makkonen, T., Makwana, R., Malaquias, A., Malizia, A., Manas, P., Manning, A., Manso, M. E., Mantica, P., Mantsinen, M., Manzanares, A., Maquet, P., Marandet, Y., Marcenko, N., Marchetto, C., Marchuk, O., Marinelli, M., Marinucci, M., Markovic, T., Marocco, D., Marot, L., Marren, C. A., Marshal, R., Martin, A., Martin, Y., Martin de Aguilera, A., Martinez, F. J., Martin-Solis, J. R., Martynova, Y., Maruyama, S., Masiello, A., Maslov, M., Matejcik, S., Mattei, M., Maviglia, F., Mayer, M., Mayoral, M. L., May-Smith, T., Mazon, D., Mazzotta, C., Mcadams, R., Mccarthy, P. J., Mcclements, K. G., Mccormack, O., Mccullen, P. A., Mcdonald, D., Mcintosh, S., Mckean, R., Mckehon, J., Meadows, R. C., Meakins, A., Medina, F., Medland, M., Medley, S., Meigh, S., Meigs, A. G., Meisl, G., Meitner, S., Meneses, L., Menmuir, S., Mergia, K., Merrigan, I. 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W., Roccella, R., Rodionov, R., Rodrigues, P., Rodriguez, J., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Romazanov, J., Rowe, S., Rubel, M., Rubinacci, G., Rubino, G., Ruchko, L., Ruiz, M., Ruset, C., Rzadkiewicz, J., Saarelma, S., Sabot, R., Safi, E., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salmon, R., Salzedas, F., Samaddar, D., Samm, U., Sandiford, D., Santa, P., Santala, M. I. K., Santos, B., Santucci, A., Sartori, F., Sartori, R., Sauter, O., Scannell, R., Schlummer, T., Schmid, K., Schmidt, V., Schmuck, S., Schneider, M., Schoepf, K., Schworer, D., Scott, S. D., Sergienko, G., Sertoli, M., Shabbir, A., Sharapov, S. E., Shaw, A., Shaw, R., Sheikh, H., Shepherd, A., Shevelev, A., Shumack, A., Sias, G., Sibbald, M., Sieglin, B., Silburn, S., Silva, A., Silva, C., Simmons, P. A., Simpson, J., Simpson-Hutchinson, J., Sinha, A., Sipila, S. K., Sips, A. C. C., Siren, P., Sirinelli, A., Sjostrand, H., Skiba, M., Skilton, R., Slabkowska, K., Slade, B., Smith, N., Smith, P. G., Smith, R., Smith, T. J., Smithies, M., Snoj, L., Soare, S., Solano, E. R., Somers, A., Sommariva, C., Sonato, P., Sopplesa, A., Sousa, J., Sozzi, C., Spagnolo, S., Spelzini, T., Spineanu, F., Stables, G., Stamatelatos, I., Stamp, M. F., Staniec, P., Stankunas, G., Stan-Sion, C., Stead, M. J., Stefanikova, E., Stepanov, I., Stephen, A. V., Stephen, M., Stevens, A., Steven, B. D., Strachan, J., Strand, P., Strauss, H. R., Strom, P., Stubbs, G., Studholme, W., Subba, F., Summers, H. P., Svensson, J., Swiderski, L., Szabolics, T., Szawlowski, M., Szepesi, G., Suzuki, T. T., Tal, B., Tala, T., Talbot, A. R., Talebzadeh, S., Taliercio, C., Tamain, P., Tame, C., Tang, W., Tardocchi, M., Taroni, L., Taylor, D., Taylor, K. A., Tegnered, D., Telesca, G., Teplova, N., Terranova, D., Testa, D., Tholerus, E., Thomas, J., Thomas, J. D., Thomas, P., Thompson, A., Thompson, C. A., Thompson, V. K., Thorne, L., Thornton, A., Thrysoe, A. S., Tigwell, P. A., Tipton, N., Tiseanu, I., Tojo, H., Tokitani, M., Tolias, P., Tomes, M., Tonner, P., Towndrow, M., Trimble, P., Tripsky, M., Tsalas, M., Tsavalas, P., Tskhakaya Jun, D., Turner, I., Turner, M. M., Turnyanskiy, M., Tvalashvili, G., Tyrrell, S. G. J., Uccello, A., Ul-Abidin, Z., Uljanovs, J., Ulyatt, D., Urano, H., Uytdenhouwen, I., Vadgama, A. P., Valcarcel, D., Valentinuzzi, M., Valisa, M., Vallejos Olivares, P., Valovic, M., Van De Mortel, M., Van Eester, D., Van Renterghem, W., van Rooij, G. J., Varje, J., Varoutis, S., Vartanian, S., Vasava, K., Vasilopoulou, T., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Verona Rinati, G., Veshchev, E., Vianello, N., Vicente, J., Viezzer, E., Villari, S., Villone, F., Vincenzi, P., Vinyar, I., Viola, B., Vitins, A., Vizvary, Z., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vora, N., Vu, T., Pires de Sa, W. W., Wakeling, B., Waldon, C. W. F., Walkden, N., Walker, M., Walker, R., Walsh, M., Wang, E., Wang, N., Warder, S., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Weckmann, A., Weiland, J., Weisen, H., Weiszflog, M., Wellstood, C., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Widdowson, A. M., Wiesen, S., Wilkinson, J., Williams, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wilson, J., Wischmeier, M., Withenshaw, G., Withycombe, A., Witts, D. M., Wood, D., Wood, R., Woodley, C., Wray, S., Wright, J., Wright, J. C., Wu, J., Wukitch, S., Wynn, A., Xu, T., Yadikin, D., Yanling, W., Yao, L., Yavorskij, V., Yoo, M. G., Young, C., Young, D., Young, I. D., Young, R., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zarins, A., Zastrow, K. D., Zerbini, M., Zhang, W., Zhou, Y., Zilli, E., Zoita, V., Zoletnik, S., Zychor, I., Max-Planck-Institut für Plasmaphysik [Garching] (IPP), Institute of Energy and Climate Research - Plasma Physics (IEK-4), Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association-Helmholtz-Gemeinschaft = Helmholtz Association, Universidade do Minho, Laboratoire de Mécanique, Modélisation et Procédés Propres (M2P2), Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Aix Marseille Université (AMU), Drenik, A., Brezinsek, S., Carvalho, P., Huber, V., Osterman, N., Matthews, G. F., Nemec, M., Litaudon, X., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Andersson Sunden, E., Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Baron Wiechec, A., Barrera Orte, L., Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. 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W., Coffey, I., Colas, L., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M. P., Craciunescu, T., Cramp, S., Craven, R., Crisanti, F., Croci, G., Croft, D., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarnecka, A., Dabirikhah, H., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., Davies, O., Davis, W., Day, C., Day, I. E., De Bock, M., de Castro, A., de la Cal, E., de la Luna, E., De Masi, G., de Pablos, J. L., De Temmerman, G., De Tommasi, G., de Vries, P., Deakin, K., Deane, J., Degli Agostini, F., Dejarnac, R., Delabie, E., den Harder, N., Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dinca, P., D'Inca, R., Ding, B., Dittmar, T., Doerk, H., Doerner, R. P., Donne, T., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Drewelow, P., Drews, P., Duckworth, P., Dumont, R., Dumortier, P., Dunai, D., Dunne, M., Duran, I., Durodie, F., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edmond, J., Edwards, A. M., Edwards, J., Eich, T., Ekedahl, A., El-Jorf, R., Elsmore, C. G., Enachescu, M., Ericsson, G., Eriksson, F., Eriksson, J., Eriksson, L. G., Esposito, B., Esquembri, S., Esser, H. G., Esteve, D., Evans, B., Evans, G. E., Evison, G., Ewart, G. D., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Fasoli, A., Faustin, J. M., Fawlk, N., Fazendeiro, L., Fedorczak, N., Felton, R. C., Fenton, K., Fernades, A., Fernandes, H., Ferreira, J., Fessey, J. A., Fevrier, O., Ficker, O., Field, A., Fietz, S., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Fonnesu, N., Fontdecaba, J. 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A., Horacek, J., Hornung, G., Horton, A. R., Horton, L. D., Horvath, L., Hotchin, S. P., Hough, M. R., Howarth, P. J., Hubbard, A., Huber, A., Huddleston, T. M., Hughes, M., Huijsmans, G. T. A., Hunter, C. L., Huynh, P., Hynes, A. M., Iglesias, D., Imazawa, N., Imbeaux, F., Imrisek, M., Incelli, M., Innocente, P., Irishkin, M., Ivanova-Stanik, I., Jachmich, S., Jacobsen, A. S., Jacquet, P., Jansons, J., Jardin, A., Jarvinen, A., Jaulmes, F., Jednorog, S., Jenkins, I., Jeong, C., Jepu, I., Joffrin, E., Johnson, R., Johnson, T., Johnston, J., Joita, L., Jones, G., Jones, T. T. C., Hoshino, K. K., Kallenbach, A., Kamiya, K., Kaniewski, J., Kantor, A., Kappatou, A., Karhunen, J., Karkinsky, D., Karnowska, I., Kaufman, M., Kaveney, G., Kazakov, Y., Kazantzidis, V., Keeling, D. L., Keenan, T., Keep, J., Kempenaars, M., Kennedy, C., Kenny, D., Kent, J., Kent, O. N., Khilkevich, E., Kim, H. T., Kim, H. S., Kinch, A., King, C., King, D., King, R. F., Kinna, D. 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Warder, S, Warren, R, Waterhouse, J, Watkins, N, Watts, C, Wauters, T, Weckmann, A, Weiland, J, Weisen, H, Weiszflog, M, Wellstood, C, West, A, Wheatley, M, Whetham, S, Whitehead, A, Whitehead, B, Widdowson, A, Wiesen, S, Wilkinson, J, Williams, J, Williams, M, Wilson, A, Wilson, D, Wilson, H, Wilson, J, Wischmeier, M, Withenshaw, G, Withycombe, A, Witts, D, Wood, D, Wood, R, Woodley, C, Wray, S, Wright, J, Wu, J, Wukitch, S, Wynn, A, Xu, T, Yadikin, D, Yanling, W, Yao, L, Yavorskij, V, Yoo, M, Young, C, Young, D, Young, I, Young, R, Zacks, J, Zagorski, R, Zaitsev, F, Zanino, R, Zarins, A, Zastrow, K, Zerbini, M, Zhang, W, Zhou, Y, Zilli, E, Zoita, V, Zoletnik, S, Zychor, I, JET Contributors, Universidade do Minho = University of Minho [Braga], and Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Materials science, Image processing, Video camera, Hot spot (veterinary medicine), 01 natural sciences, 010305 fluids & plasmas, law.invention, [SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph], Image analysis, Plasma-wall interaction, Optics, law, 0103 physical sciences, General Materials Science, Camera image, 010306 general physics, Civil and Structural Engineering, Settore FIS/01, Jet (fluid), Pixel, business.industry, ITER-like wall, Mechanical Engineering, Divertor, [SPI.FLUID]Engineering Sciences [physics]/Reactive fluid environment, Settore ING-IND/18 - Fisica dei Reattori Nucleari, JET, Nuclear Energy and Engineering, visual_art, visual_art.visual_art_medium, Tile, Image analysi, business
Abstract: International audience; Hot spots on the divertor tiles at JET result in overestimation of the tile surface temperature which causes unnecessary termination of pulses. However, the appearance of hot spots can also indicate the condition of the divertor tile surfaces. To analyse the behaviour of the hot spots in the outer divertor tiles of JET, a simple image processing algorithm is developed. The algorithm isolates areas of bright pixels in the camera image and compares them to previously identified hot spots. The activity of the hot spots is then linked to values of other signals and parameters in the same time intervals. The operation of the detection algorithm was studied in a limited pulse range with high hot spot activity on the divertor tiles 5, 6 and 7. This allowed us to optimise the values of the controlling parameters. Then, the wider applicability of the method has been demonstrated by the analysis of the hot spot behaviour in a whole experimental campaign.
Published: 2019

23. Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial

Author: Albert C Ludolph, Joachim Schuster, Johannes Dorst, Luc Dupuis, Jens Dreyhaupt, Jochen H Weishaupt, Jan Kassubek, Ulrike Weiland, Susanne Petri, Thomas Meyer, Julian Grosskreutz, Berthold Schrank, Matthias Boentert, Alexander Emmer, Andreas Hermann, Daniel Zeller, Johannes Prudlo, Andrea S Winkler, Torsten Grehl, Michael T Heneka, Siw Wollebæk Johannesen, Bettina Göricke, Andreas Funke, Dagmar Kettemann, Robert Meyer, Kai Gruhn, Peter Schwenkreis, Philipp Stude, Delia Kurzwelly, Alexander Storch, Nicole Richter, Tobias Frank, Katharina Hein, Frank Hanisch, Dagmar Hanke, Torsten Kraya, Andreas Posa, Martina Romanakova, Susanne Schilling, Susanne Abdulla, Sebastian Böselt, Claas Janssen, Imken Lange, Xenia Kobeleva, Sonja Körner, Katja Kollewe, Alma Osmanovic, Nicole Scharn, Klaus J Rath, Christiane Dahms, Anne Gunkel, Bianka Heiling, Thomas Ringer, Uta Smesny, Sarah Baumeister, Achim Berthele, Sarah Bublitz, Esra Akova-Öztürk, Bianca Stubbe-Dräger, Alexandra Rahmann, Charlotte Young, Peter Young, Dobri Baldaranov, Ulrich Bogdahn, Andrei Khomenko, Wilhelm Schulte-Mattler, Christina Stadler, Susanne Husung, Simone Tesar, Nigar Dargah-Zaden, Christina Last, Eva Langer, Ann-Sophie Lauenstein, Eckard Lensch, Carolyn Mc Farlane, Heike Fischer-Brasse, Klara Orbán, Bertold Schrank, Sonja Schürger, Stephan Klebe, Peter Kraft, Thomas Musacchio, Carola Seiler, University of Ulm (UUlm), Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hannover Medical School [Hannover] (MHH), Humboldt-Universität zu Berlin, Jena University Hospital [Jena], DKD Helios Klinik Wiesbaden [Wiesbaden, Germany] (DKD HELIOS Medical Center), University Hospital Münster - Universitaetsklinikum Muenster [Germany] (UKM), Martin-Luther-University Halle-Wittenberg, University Hospital Carl Gustav Carus [Dresden, Germany], Technische Universität Dresden = Dresden University of Technology (TU Dresden), University of Würzburg = Universität Würzburg, University of Rostock, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Ruhr-Universität Bochum [Bochum], University of Bonn, University of Regensburg, University Medical Center Göttingen (UMG), RAS-ALS Study Group: Andreas Funke, Dagmar Kettemann, Robert Meyer, Thomas Meyer, Torsten Grehl, Kai Gruhn, Peter Schwenkreis, Philipp Stude, Michael T Heneka, Delia Kurzwelly, Andreas Hermann, Alexander Storch, Nicole Richter, Tobias Frank, Bettina Göricke, Katharina Hein, Alexander Emmer, Frank Hanisch, Dagmar Hanke, Torsten Kraya, Andreas Posa, Martina Romanakova, Susanne Schilling, Susanne Abdulla, Sebastian Böselt, Dagmar Hanke, Claas Janssen, Imken Lange, Xenia Kobeleva, Sonja Körner, Katja Kollewe, Alma Osmanovic, Susanne Petri, Nicole Scharn, Klaus J Rath, Christiane Dahms, Julian Grosskreutz, Anne Gunkel, Bianka Heiling, Thomas Ringer, Uta Smesny, Sarah Baumeister, Achim Berthele, Sarah Bublitz, Andrea S Winkler, Esra Akova-Öztürk, Matthias Boentert, Bianca Stubbe-Dräger, Alexandra Rahmann, Charlotte Young, Peter Young, Dobri Baldaranov, Ulrich Bogdahn, Siw Wollebæk Johannesen, Andrei Khomenko, Wilhelm Schulte-Mattler, Christina Stadler, Susanne Husung, Johannes Prudlo, Simone Tesar, Nigar Dargah-Zaden, Christina Last, Eva Langer, Albert C Ludolph, Jochen H Weishaupt, Ulrike Weiland, Ann-Sophie Lauenstein, Eckard Lensch, Carolyn Mc Farlane, Heike Fischer-Brasse, Klara Orbán, Bertold Schrank, Sonja Schürger, Stephan Klebe, Peter Kraft, Thomas Musacchio, Carola Seiler, Daniel Zeller., Technical University of Munich (TUM), Dieterle, Stéphane, Humboldt University Of Berlin, and Klebe, Stephan (Beitragende*r)
Subjects: Male, 0301 basic medicine, [SDV]Life Sciences [q-bio], Vital Capacity, Medizin, Body Mass Index, chemistry.chemical_compound, MESH: Riluzole, 0302 clinical medicine, Clinical endpoint, Medicine, MESH: Double-Blind Method, Amyotrophic lateral sclerosis, MESH: Amyotrophic Lateral Sclerosis, MESH: Treatment Outcome, MESH: Aged, education.field_of_study, Riluzole, MESH: Middle Aged, Hazard ratio, MESH: Neuroprotective Agents, Middle Aged, 3. Good health, [SDV] Life Sciences [q-bio], Neuroprotective Agents, Treatment Outcome, Indans, Disease Progression, Female, MESH: Disease Progression, medicine.drug, medicine.medical_specialty, Population, Placebo, MESH: Body Mass Index, 03 medical and health sciences, Double-Blind Method, Internal medicine, Humans, education, Aged, Retrospective Studies, Rasagiline, MESH: Humans, business.industry, Amyotrophic Lateral Sclerosis, MESH: Retrospective Studies, MESH: Vital Capacity, medicine.disease, MESH: Indans, MESH: Male, Clinical trial, 030104 developmental biology, chemistry, Neurology (clinical), business, MESH: Female, 030217 neurology & neurosurgery
Abstract: International audience; Background: Rasagiline, a monoamine oxidase B inhibitor with neuroprotective potential in Parkinson's disease, has shown a disease-modifying effect in the SOD1-Gly93Ala low-expressing mouse model of amyotrophic lateral sclerosis, both alone and in combination with riluzole. We sought to test whether or not rasagiline 1 mg/day can prolong survival in patients with amyotrophic lateral sclerosis also receiving riluzole.Methods: Patients with possible, probable, or definite amyotrophic lateral sclerosis were enrolled to our randomised, placebo-controlled, parallel-group, double-blind, phase 2 trial from 15 German network for motor neuron diseases (MND-NET) centres (university hospitals or clinics). Eligible patients were aged at least 18 years, had onset of progressive weakness within the 36 months before the study, had disease duration of more than 6 months and less than 3 years, and had a best-sitting slow vital capacity of at least 50%. After a 4-week screening period, eligible patients were randomly assigned (1:1) to receive either rasagiline (1 mg/day) or placebo in addition to riluzole (100 mg/day), after stratification for site of onset (bulbar or spinal) and study centre. Patients and all personnel assessing outcome parameters were masked to treatment allocation. Patients were followed up 2, 6, 12, and 18 months after randomisation. The primary endpoint was survival time, defined as the time to death or time to study cutoff date (ie, the last patient's last visit plus 14 days). Analyses of primary outcome and safety measures were done in all patients who received at least one dose of trial treatment (intention-to-treat population). The trial is registered with ClinicalTrials.gov, number NCT01879241.Findings: Between July 2, 2013, and Nov 11, 2014, 273 patients were screened for eligibility, and 252 patients were randomly assigned to receive rasagiline (n=127) or placebo (n=125). 126 patients taking rasagiline and 125 taking placebo were included in the intention-to-treat analysis. For the primary outcome, the survival probability at the end of the study was 0·43 (95% CI 0·25-0·59) in the rasagiline group (n=126) and 0·53 (0·43-0·62) in the placebo group (n=125). The estimated effect size (hazard ratio) was 0·91 (one-sided 97·5% CI -infinity to 1·34; p=0·31). Rasagiline was well tolerated, and most adverse events were due to amyotrophic lateral sclerosis disease progression rather than treatment; the most frequent of these were dysphagia (32 [25%] taking rasagiline vs 24 [19%] taking placebo) and respiratory failure (25 [20%] vs 31 [25%]). Frequency of adverse events were comparable between both groups.Interpretation: Rasagiline was safe in patients with amyotrophic lateral sclerosis. There was no difference between groups in the primary outcome of survival, although post-hoc analysis suggested that rasagiline might modify disease progression in patients with an initial slope of Amyotrophic Lateral Sclerosis Functional Rating Scale Revised greater than 0·5 points per month at baseline. This should be confirmed in another clinical trial.Funding: Teva Pharmaceutical Industries.
Published: 2018

24. Pathological findings in African buffaloes (Syncerus caffer) in South Africa

Author: Daniel B. Woodburn, Johan Steyl, Elizabeth C. du Plessis, Rick D. Last, Bjorn Reininghaus, and Emily P. Mitchell
Subjects: Male, Veterinary medicine, Tuberculosis, Buffaloes, animal diseases, Population, Prevalence, Disease, african buffalo, Communicable Diseases, South Africa, Cause of Death, SF600-1100, parasitic diseases, medicine, Animals, Rift Valley fever, education, Original Research, Retrospective Studies, Skin, Cause of death, disease, education.field_of_study, General Veterinary, Foot-and-mouth disease, business.industry, Brucellosis, General Medicine, Abortion, Veterinary, medicine.disease, wildlife veterinarians, syncerus caffer, Female, pathology, Autopsy, business
Abstract: The African buffalo (Syncerus caffer) is an iconic species of South African megafauna. As the farmed buffalo population expands, the potential impacts on population health and disease transmission warrant investigation. A retrospective study of skin biopsy and necropsy samples from 429 animals was performed to assess the spectrum of conditions seen in buffaloes in South Africa. Determination of the cause of death (or euthanasia) could not be made in 33.1% (136/411) of the necropsy cases submitted due to autolysis or the absence of significant lesions in the samples submitted. Infectious and parasitic diseases accounted for 53.5% (147/275) of adult fatal cases and non-infectious conditions accounted for 34.9% (96/275). Abortions and neonatal deaths made up 11.6% (32/275) of necropsy cases. Rift Valley fever, bovine viral diarrhoea, malignant catarrhal fever, tuberculosis, bacterial pneumonia, anaesthetic deaths, cachexia and hepatotoxic lesions were the most common causes of death. The range of infectious, parasitic and non-infectious diseases to which African buffaloes were susceptible was largely similar to diseases in domestic cattle which supports concerns regarding disease transmission between the two species. The similarity between diseases experienced in both species will assist wildlife veterinarians in the diagnosis and treatment of diseases in captive African buffaloes. The present study likely does not represent accurate disease prevalence data within the source population of buffaloes, and diseases such as anthrax, brucellosis and foot and mouth disease are under-represented in this study. Hepatic ductal plate abnormalities and haemorrhagic septicaemia have not, to our knowledge, been previously reported in African buffaloes.
Published: 2021

25. 2021 Update of the International Council for Standardization in Haematology Recommendations for Laboratory Measurement of Direct Oral Anticoagulants

Author: Robert C. Gosselin, Edelgard Lindhoff-Last, Steve Kitchen, Yohko Kawai, Cecilia Guillermo, Jonathan Douxfils, Isabelle Gouin-Thibault, Shannon M. Bates, Emmanuel J. Favaloro, Dorothy M. Adcock, Université de Namur [Namur] (UNamur), McMaster University [Hamilton, Ontario], Westmead Hospital [Sydney], Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Universidad de la República [Montevideo] (UCUR), University of California [Davis] (UC Davis), University of California, Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Universidad de la República [Montevideo] (UDELAR), and University of California (UC)
Subjects: medicine.medical_specialty, Consensus, Standardization, diagnosis management, [SDV]Life Sciences [q-bio], MEDLINE, Hemorrhage, 030204 cardiovascular system & hematology, direct oral anticoagulants, Food and drug administration, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Predictive Value of Tests, medicine, Humans, Intensive care medicine, Blood Coagulation, Rivaroxaban, Evidence-Based Medicine, business.industry, Reproducibility of Results, Hematology, Anticoagulation Reversal, 3. Good health, chemistry, Point-of-Care Testing, 030220 oncology & carcinogenesis, Betrixaban, Apixaban, Blood Coagulation Tests, Drug Monitoring, Good laboratory practice, business, laboratory, guidance, Factor Xa Inhibitors, medicine.drug, Andexanet alfa
Abstract: In 2018, the International Council for Standardization in Haematology (ICSH) published a consensus document providing guidance for laboratories on measuring direct oral anticoagulants (DOACs). Since that publication, several significant changes related to DOACs have occurred, including the approval of a new DOAC by the Food and Drug Administration, betrixaban, and a specific DOAC reversal agent intended for use when the reversal of anticoagulation with apixaban or rivaroxaban is needed due to life-threatening or uncontrolled bleeding, andexanet alfa. In addition, this ICSH Working Party recognized areas where additional information was warranted, including patient population considerations and updates in point-of-care testing. The information in this manuscript supplements our previous ICSH DOAC laboratory guidance document. The recommendations provided are based on (1) information from peer-reviewed publications about laboratory measurement of DOACs, (2) contributing author's personal experience/expert opinion and (3) good laboratory practice.
Published: 2021

26. Broadening the range of use cases for ivermectin – a review of the evidence

Author: Christian Kositz, John Bradley, Harry Hutchins, Anna Last, Umberto D'Alessandro, and Michael Marks
Subjects: animal diseases, 030231 tropical medicine, Review Article, Onchocerciasis, 03 medical and health sciences, Scabies, 0302 clinical medicine, Ivermectin, parasitic diseases, Medicine, Animals, Humans, 030212 general & internal medicine, Lymphatic filariasis, biology, Antiparasitic Agents, business.industry, Public Health, Environmental and Occupational Health, Anopheles, Neglected Diseases, General Medicine, medicine.disease, biology.organism_classification, Antiparasitic agent, Malaria, Infectious Diseases, Immunology, Neglected tropical diseases, Parasitology, business, medicine.drug
Abstract: Ivermectin is a broad-spectrum antiparasitic agent that interferes with glutamate-gated chloride channels found in invertebrates but not in vertebrate species. Mass drug administration (MDA) with ivermectin-based regimes has been a mainstay of elimination efforts targeting onchocerciasis and lymphatic filariasis for more than 3 decades. More recently, interest in the use of ivermectin to control other neglected tropical diseases (NTDs) such as soil-transmitted helminths and scabies has grown. Interest has been further stimulated by the fact that ivermectin displays endectocidal efficacy against various Anopheles species capable of transmitting malaria. Therefore there is growing interest in using ivermectin MDA as a tool that might aid in the control of both malaria and several NTDs. In this review we outline the evidence base to date on these emerging indications for ivermectin MDA with reference to clinical and public health data and discuss the rationale for evaluating the range of impacts of a malaria ivermectin MDA on other NTDs.
Published: 2021

27. Accelerating quantum computer developments

Author: Garrelt J. N. Alberts, M. Adriaan Rol, Thorsten Last, Benno W. Broer, Cornelis C. Bultink, Matthijs S. C. Rijlaarsdam, and Amber E. Van Hauwermeiren
Subjects: Standardization, Computer science, business.industry, Supply chain, Data management, Condensed Matter Physics, Supercomputer, 01 natural sciences, Atomic and Molecular Physics, and Optics, Manufacturing engineering, 010305 fluids & plasmas, Quantum technology, Control and Systems Engineering, 0103 physical sciences, New product development, Product (category theory), Electrical and Electronic Engineering, 010306 general physics, business, Quantum computer
Abstract: Product developmentGiven the recent breakthroughs in quantum technology development in R& D labs all over the world, the perspective of high-tech companies has changed.Productdevelopment is initiated next to the existingresearchandtechnologydevelopment activities.Quantum computer product roadmapConsidering the quantum computer as a product requires standardization and integration of all its building blocks and a mature supply chain that can provide high-quality components and can ensure security of supply. The product development approach puts focus on functionality and performance requirements of the product and uses state-of-the-art technology to build the product. Based on the expected requirements of future products it is possible to outline a product development roadmap.It is expected that a fully functional quantum computer will be available within a decade from now, and will be used by the High Performance Computing (HPC) market, where it will replace (part of) the supercomputers that are currently used for complex calculations and data management. In the short term, a partly functional quantum computer will be available and of interest to the R&D market, which has a need for such a product to expedite their quantum technology developments.ImpaQT projectIn this paper, we present the product development approach and roadmap for quantum computers, based on superconducting circuits as an example. A group of companies in the Dutch quantum ecosystem (Quantum Delta) have joined forces and have started theImpaQTproject. The companies of the ImpaQT consortium form a local supply chain for key components of quantum computers.This paper shows that quantum community has reached the next level of maturity and that the quantum computer as a commercial product looks set to become a reality.
Published: 2021

28. Metaplastic carcinoma of the breast: Clinicopathological features and treatment outcomes with long‑term follow up

Author: Aron Gortman, Noel Aherne, Justin Westhuyzen, Julan Amalaseelan, Patrick Dwyer, Matthew Hoffmann, Andrew Last, and Thomas Shakespeare
Subjects: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Metaplastic carcinoma, Treatment outcome, Cancer, Articles, Disease, Metaplastic Breast Carcinoma, medicine.disease, Molecular medicine, Breast cancer, Median follow-up, Internal medicine, Medicine, skin and connective tissue diseases, business
Abstract: Metaplastic breast carcinoma is an uncommon subtype of invasive ductal carcinoma with a tendency towards poorer clinical outcomes. Following ethical approval, the current study reviewed the institutional records of ~2,500 women with breast cancer. A total of 14 cases of metaplastic breast cancer were reviewed for management and treatment outcomes. The results demonstrated that patients had median follow up of 30 months, a 5-year disease-free survival of 57.1% and 5-year overall survival of 57.1%. The majority of patients had at least T2 disease and all tumours were high grade. Additionally, most patients were triple negative and nodal metastases were uncommon. Metaplastic breast cancer is an aggressive variant of invasive breast cancer. Most patients can be treated with breast conservation and survival parameters tend to be worse than more common breast cancer subtypes.
Published: 2021

29. Systematic review of clinician-directed nudges in healthcare contexts

Author: Briana S Last, Alison M Buttenheim, Carter E Timon, Nandita Mitra, and Rinad S Beidas
Subjects: protocols & guidelines, Clinical Decision-Making, Psychological intervention, PsycINFO, 01 natural sciences, quality in health care, health & safety, EconLit, 03 medical and health sciences, 0302 clinical medicine, Health care, Humans, health economics, Medicine, 030212 general & internal medicine, 0101 mathematics, Medical education, Health economics, Nudge theory, business.industry, 010102 general mathematics, General Medicine, Bioethics, Snowball sampling, Health Facilities, Health Services Research, business, Delivery of Health Care
Abstract: ObjectiveNudges are interventions that alter the way options are presented, enabling individuals to more easily select the best option. Health systems and researchers have tested nudges to shape clinician decision-making with the aim of improving healthcare service delivery. We aimed to systematically study the use and effectiveness of nudges designed to improve clinicians’ decisions in healthcare settings.DesignA systematic review was conducted to collect and consolidate results from studies testing nudges and to determine whether nudges directed at improving clinical decisions in healthcare settings across clinician types were effective. We systematically searched seven databases (EBSCO MegaFILE, EconLit, Embase, PsycINFO, PubMed, Scopus and Web of Science) and used a snowball sampling technique to identify peer-reviewed published studies available between 1 January 1984 and 22 April 2020. Eligible studies were critically appraised and narratively synthesised. We categorised nudges according to a taxonomy derived from the Nuffield Council on Bioethics. Included studies were appraised using the Cochrane Risk of Bias Assessment Tool.ResultsWe screened 3608 studies and 39 studies met our criteria. The majority of the studies (90%) were conducted in the USA and 36% were randomised controlled trials. The most commonly studied nudge intervention (46%) framed information for clinicians, often through peer comparison feedback. Nudges that guided clinical decisions through default options or by enabling choice were also frequently studied (31%). Information framing, default and enabling choice nudges showed promise, whereas the effectiveness of other nudge types was mixed. Given the inclusion of non-experimental designs, only a small portion of studies were at minimal risk of bias (33%) across all Cochrane criteria.ConclusionsNudges that frame information, change default options or enable choice are frequently studied and show promise in improving clinical decision-making. Future work should examine how nudges compare to non-nudge interventions (eg, policy interventions) in improving healthcare.
Published: 2021

30. The Current Role of Dexmedetomidine as Neuroprotective Agent: An Updated Review

Author: Zaara Liaquat, Xiaoying Xu, Prince Last Mudenda Zilundu, Rao Fu, and Lihua Zhou
Subjects: 0301 basic medicine, Agonist, medicine.drug_class, Sedation, Neurosciences. Biological psychiatry. Neuropsychiatry, Review, Bioinformatics, Neuroprotection, necrosis, neuroinflammation, 03 medical and health sciences, 0302 clinical medicine, caspase 8, Medicine, Dexmedetomidine, excitatory amino acid transporter 3, Neuroinflammation, business.industry, General Neuroscience, focal adhesion kinase, apoptosis, dexmedetomidine, excitotoxic neurotransmitter, Clinical trial, 030104 developmental biology, Anesthetic, neuroprotection, Animal studies, nerve injury, medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug, RC321-571
Abstract: Dexmedetomidine, selective α2-adrenergic agonist dexmedetomidine, has been widely used clinically for sedation and anesthesia. The role of dexmedetomidine has been an interesting topic of neonatological and anesthetic research since a series of advantages of dexmedetomidine, such as enhancing recovery from surgery, reducing opioid prescription, decreasing sympathetic tone, inhibiting inflammatory reactions, and protecting organs, were reported. Particularly, an increasing number of animal studies have demonstrated that dexmedetomidine ameliorates the neurological outcomes associated with various brain and spinal cord injuries. In addition, a growing number of clinical trials have reported the efficacy of dexmedetomidine for decreasing the rates of postoperative neurological dysfunction, such as delirium and stroke, which strongly highlights the possibility of dexmedetomidine functioning as a neuroprotective agent for future clinical use. Mechanism studies have linked dexmedetomidine’s neuroprotective properties with its modulation of neuroinflammation, apoptosis, oxidative stress, and synaptic plasticity via the α2-adrenergic receptor, dependently or independently. By reviewing recent advances and preclinical and clinical evidence on the neuroprotective effects of dexmedetomidine, we hope to provide a complete understanding of the above mechanism and provide insights into the potential efficacy of this agent in clinical use for patients.
Published: 2021

31. Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion

Author: Prince Last Mudenda Zilundu, Xiaoying Xu, Zaara Liaquat, Yaqiong Wang, Ke Zhong, Rao Fu, and Lihua Zhou
Subjects: medicine.medical_specialty, QH301-705.5, Proto-Oncogene Proteins c-jun, Nitric Oxide Synthase Type I, Neuroprotection, Article, Avulsion, Rats, Sprague-Dawley, Myelin, Atrophy, motor neuron ultrastructure, Anterior Horn Cells, Internal medicine, Forelimb, medicine, Animals, Brachial Plexus, Biology (General), Radiculopathy, Motor Neurons, business.industry, ventral horn, c-jun, motor function, General Medicine, Recovery of Function, Motor neuron, medicine.disease, brachial plexus roots avulsion, Oxidative Stress, medicine.anatomical_structure, Endocrinology, Neuroprotective Agents, nervous system, Nitrosative Stress, business, Spinal Nerve Roots, Brachial plexus
Abstract: Brachial plexus root avulsions cause debilitating upper limb paralysis. Short-term neuroprotective treatments have reported preservation of motor neurons and function in model animals while reports of long-term benefits of such treatments are scarce, especially the morphological sequelae. This morphological study investigated the long-term suppression of c-Jun- and neuronal nitric oxide synthase (nNOS) (neuroprotective treatments for one month) on the motor neuron survival, ultrastructural features of lower motor neurons, and forelimb function at six months after brachial plexus roots avulsion. Neuroprotective treatments reduced oxidative stress and preserved ventral horn motor neurons at the end of the 28-day treatment period relative to vehicle treated ones. Motor neuron sparing was associated with suppression of c-Jun, nNOS, and pro-apoptotic proteins Bim and caspases at this time point. Following 6 months of survival, neutral red staining revealed a significant loss of most of the motor neurons and ventral horn atrophy in the avulsed C6, 7, and 8 cervical segments among the vehicle-treated rats (n = 4). However, rats that received neuroprotective treatments c-Jun JNK inhibitor, SP600125 (n = 4) and a selective inhibitor of nNOS, 7-nitroindazole (n = 4), retained over half of their motor neurons in the ipsilateral avulsed side compared. Myelinated axons in the avulsed ventral horns of vehicle-treated rats were smaller but numerous compared to the intact contralateral ventral horns or neuroprotective-treated groups. In the neuroprotective treatment groups, there was the preservation of myelin thickness around large-caliber axons. Ultrastructural evaluation also confirmed the preservation of organelles including mitochondria and synapses in the two groups that received neuroprotective treatments compared with vehicle controls. Also, forelimb functional evaluation demonstrated that neuroprotective treatments improved functional abilities in the rats. In conclusion, neuroprotective treatments aimed at suppressing degenerative c-Jun and nNOS attenuated apoptosis, provided long-term preservation of motor neurons, their organelles, ventral horn size, and forelimb function.
Published: 2021

32. Reduction of cardiac imaging tests during the COVID-19 pandemic: The case of Italy. Findings from the IAEA Non-invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID)

Author: Dondi, M., Milan, E., Pontone, G., Hirschfeld, C. B., Williams, M., Shaw, L. J., Pynda, Y., Raggi, P., Cerci, R., Vitola, J., Better, N., Villines, T. C., Dorbala, S., Pascual, T. N. B., Giubbini, R., Einstein, A. J., Paez, D., Italy: Domenico Albano, Pierpaolo, Alongi, Gaspare, Arnone, Elisa, Bagatin, Sergio, Baldari, Matteo, Bauckneht, Paolo, Bertelli, Francesco, Bianco, Rachele, Bonfiglioli, Roberto, Boni, Andrea, Bruno, Isabella, Bruno, Elena, Busnardo, Elena, Califaretti, Luca, Camoni, Aldo, Carnevale, Roberta, Casoni, Armando Ugo Cavallo, Giorgio, Cavenaghi, Franca, Chierichetti, Marcello, Chiocchi, Corrado, Cittanti, Mauro, Colletta, Umberto, Conti, Alberto, Cossu, Alberto, Cuocolo, Marco, Cuzzocrea, Maria Luisa De Rimini, Giuseppe De Vincentis, Eleonora Del Giudice, Alberico Del Torto, Veronica Della Tommasina, Rexhep, Durmo, Paola Anna Erba, Laura, Evangelista, Riccardo, Faletti, Evelina, Faragasso, Mohsen, Farsad, Paola, Ferro, Luigia, Florimonte, Viviana, Frantellizzi, Fabio Massimo Fringuelli, Marco, Gatti, Angela, Gaudiano, Alessia, Gimelli, Raffaele, Giubbini, Francesca, Giuffrida, Salvatore, Ialuna, Riccardo, Laudicella, Lucia, Leccisotti, Lucia, Leva, Liga, Riccardo, Carlo, Liguori, Giampiero, Longo, Margherita, Maffione, Maria Elisabetta Mancini, Claudio, Marcassa, Elisa, Milan, Barbara, Nardi, Sara, Pacella, Giovanna, Pepe, Gianluca, Pontone, Sabina, Pulizzi, Natale, Quartuccio, Lucia, Rampin, Fabrizio, Ricci, Pierluigi, Rossini, Giuseppe, Rubini, Vincenzo, Russo, Gian Mauro Sacchetti, Gianmario, Sambuceti, Massimo, Scarano, Roberto, Sciagrà, Massimiliano, Sperandio, Antonella, Stefanelli, Guido, Ventroni, Stefania Zoboli Members from Rest of the World (alphabetically by country and last name) Afghanistan: Mohammad Nawaz Nasery Albania: Artan Goda, Ervina Shirka Algeria: Rabie Benlabgaa, Salah, Bouyoucef, Abdelkader, Medjahedi, Qais Nailli Argentina: Mariela Agolti, Roberto Nicolas Aguero, Maria del Carmen Alak, Lucia Graciela Alberguina, Guillermo, Arroñada, Andrea, Astesiano, Alfredo, Astesiano, Carolina Bas Norton, Pablo, Benteo, Juan, Blanco, Juan Manuel Bonelli, Jose Javier Bustos, Raul, Cabrejas, Jorge, Cachero, Roxana, Campisi, Alejandro, Canderoli, Silvia, Carames, Patrícia, Carrascosa, Ricardo, Castro, Oscar, Cendoya, Luciano Martin Cognigni, Carlos, Collaud, Claudia, Cortes, Javier, Courtis, Daniel, Cragnolino, Mariana, Daicz, Alejandro De La Vega, Silvia Teresa De Maria, Horacio Del Riego, Fernando, Dettori, Alejandro, Deviggiano, Laura, Dragonetti, Mario, Embon, Ruben Emilio Enriquez, Jorge, Ensinas, Fernando, Faccio, Adolfo, Facello, Diego, Garofalo, Ricardo, Geronazzo, Natalia, Gonza, Lucas, Gutierrez, Miguel Angel Guzzo, Victor, Hasbani, Melina, Huerin, Victor, Jäger, Julio Manuel Lewkowicz, Maria Nieves, A López De Munaín, Jose Maria Lotti, Alejandra, Marquez, Osvaldo, Masoli, Osvaldo Horacio Masoli, Edgardo, Mastrovito, Matias, Mayoraz, Graciela Eva Melado, Anibal, Mele, Maria Fernanda Merani, Alejandro Horacio Meretta, Susana, Molteni, Marcos, Montecinos, Eduardo, Noguera, Carlos, Novoa, Claudio Pereyra Sueldo, Sebastian Perez Ascani, Pablo, Pollono, Maria Paula Pujol, Alejandro, Radzinschi, Gustavo, Raimondi, Marcela, Redruello, Marina, Rodríguez, Matías, Rodríguez, Romina Lorena Romero, Arturo Romero Acuña, Federico, Rovaletti, Lucas San Miguel, Lucrecia, Solari, Bruno, Strada, Sonia, Traverso, Sonia Simona Traverzo, Maria del Huerto Velazquez Espeche, Juan Sebastian Weihmuller, Juan, Wolcan, Susana Zeffiro Armenia: Mari Sakanyan Australia: Scott Beuzeville, Raef, Boktor, Patrick, Butler, Jennifer, Calcott, Loretta, Carr, Virgil, Chan, Charles, Chao, Woon, Chong, Mark, Dobson, D'Arne, Downie, Girish, Dwivedi, Barry, Elison, Jean, Engela, Roslyn, Francis, Anand, Gaikwad, Ashok Gangasandra Basavaraj, Bruce, Goodwin, Robert, Greenough, Christian, Hamilton-Craig, Victar, Hsieh, Subodh, Joshi, Karin, Lederer, Kenneth, Lee, Joseph, Lee, John, Magnussen, Nghi, Mai, Gordon, Mander, Fiona, Murton, Dee, Nandurkar, Johanne, Neill, Edward, O'Rourke, Patricia, O'Sullivan, George, Pandos, Kunthi, Pathmaraj, Alexander, Pitman, Rohan, Poulter, Manuja, Premaratne, David, Prior, Lloyd, Ridley, Natalie, Rutherford, Hamid, Salehi, Connor, Saunders, Luke, Scarlett, Sujith, Seneviratne, Deepa, Shetty, Ganesh, Shrestha, Jonathan, Shulman, Vijay, Solanki, Tony, Stanton, Murch, Stuart, Michael, Stubbs, Ian, Swainson, Kim, Taubman, Andrew, Taylor, Paul, Thomas, Steven, Unger, Anthony, Upton, Shankar, Vamadevan, William Van Gaal, Johan, Verjans, Demetrius, Voutnis, Victor, Wayne, Peter, Wilson, David, Wong, Kirby, Wong, John Younger Austria: Gudrun Feuchtner, Siroos, Mirzaei, Konrad Weiss Belarus: Natallia Maroz-Vadalazhskaya Belgium: Olivier Gheysens, Filip, Homans, Rodrigo, Moreno-Reyes, Agnès, Pasquet, Veronique, Roelants, Van De Heyning Bolivia: Raúl Araujo Ríos Bosnia - Herzegovina: Valentina Soldat-Stankovic, Caroline M., Sinisa Stankovic Brazil: Maria Helena Albernaz Siqueira, Augusto, Almeida, Paulo Henrique Alves Togni, Jose Henrique Andrade, Luciana, Andrade, Carlos, Anselmi, Roberta, Araújo, Guilherme, Azevedo, Sabbrina, Bezerra, Rodrigo, Biancardi, Gabriel Blacher Grossman, Simone, Brandão, Diego Bromfman Pianta, Lara, Carreira, Bruno, Castro, Tien, Chang, Fernando Cunali, Jr., Roberto, Cury, Roberto, Dantas, Fernando de Amorim Fernandes, Andrea De Lorenzo, Robson De Macedo Filho, Fernanda, Erthal, Fabio, Fernandes, Juliano, Fernandes, Thiago Ferreira De Souza, Wilson Furlan Alves, Bruno, Ghini, Luiz, Goncalves, Ilan, Gottlieb, Marcelo, Hadlich, Vinícius, Kameoka, Ronaldo, Lima, Adna, Lima, Rafael Willain Lopes, Ricardo Machado, e Silva, Tiago, Magalhães, Fábio Martins Silva, Luiz Eduardo Mastrocola, Fábio, Medeiros, José Claudio Meneghetti, Vania, Naue, Danilo, Naves, Roberto, Nolasco, Cesar, Nomura, Joao Bruno Oliveira, Eduardo, Paixao, Filipe Penna De Carvalho, Ibraim, Pinto, Priscila, Possetti, Mayra, Quinta, Rodrigo Rizzo Nogueira Ramos, Ricardo, Rocha, Alfredo, Rodrigues, Carlos, Rodrigues, Leila, Romantini, Adelina, Sanches, Sara, Santana, Leonardo Sara da Silva, Paulo, Schvartzman, Cristina Sebastião Matushita, Tiago, Senra, Afonso, Shiozaki, Maria Eduarda Menezes de Siqueira, Cristiano, Siqueira, Paola, Smanio, Carlos Eduardo Soares, José Soares Junior, Marcio Sommer Bittencourt, Bernardo, Spiro, Cláudio Tinoco Mesquita, Jorge, Torreao, Rafael, Torres, Marly, Uellendahl, Guilherme Urpia Monte, Otávia, Veríssimo, Estevan Vieira Cabeda, Felipe Villela Pedras, Roberto, Waltrick, Marcello Zapparoli Brunei Darussalam: Hamid Naseer Bulgaria: Marina Garcheva-Tsacheva, Irena Kostadinova Cambodia: Youdaline Theng Canada: Gad Abikhzer, Rene, Barette, Benjamin, Chow, Dominique, Dabreo, Matthias, Friedrich, Ria, Garg, Mohammed Nassoh Hafez, Chris, Johnson, Marla, Kiess, Jonathon, Leipsic, Eugene, Leung, Robert, Miller, Anastasia, Oikonomou, Stephan, Probst, Idan, Roifman, Gary, Small, Vikas, Tandon, Adwait, Trivedi, James, White, Katherine Zukotynski Chile: Jose Canessa, Gabriel Castro Muñoz, Carmen, Concha, Pablo, Hidalgo, Cesar, Lovera, Teresa, Massardo, Luis Salazar Vargas Colombia: Pedro Abad, Harold, Arturo, Sandra, Ayala, Luis, Benitez, Alberto, Cadena, Carlos, Caicedo, Antonio Calderón Moncayo, Sharon, Gomez, Gutierrez Villamil, Claudia T., Claudia, Jaimes, Juan, Londoño, Juan Luis Londoño Blair, Luz, Pabon, Mauricio, Pineda, Juan Carlos Rojas, Diego, Ruiz, Manuel Valencia Escobar, Andres, Vasquez, Damiana, Vergel, Alejandro Zuluaga Costa Rica: Isabel Berrocal Gamboa, Gabriel, Castro, Ulises, González, Croatia: Ana Baric, Tonci, Batinic, Maja, Franceschi, Maja Hrabak Paar, Mladen, Jukic, Petar, Medakovic, Viktor, Persic, Marina, Prpic, Ante Punda Cuba: Juan Felipe Batista, Juan Manuel Gómez Lauchy, Yamile Marcos Gutierrez, Rayner, Menéndez, Amalia, Peix, Luis Rochela Cyprus: Christoforos Panagidis, Ioannis Petrou Czech Republic: Vaclav Engelmann, Milan, Kaminek, Vladimír, Kincl, Otto, Lang, Milan Simanek Denmark: Jawdat Abdulla, Morten, Bøttcher, Mette, Christensen, Lars Christian Gormsen, Philip, Hasbak, Søren, Hess, Paw, Holdgaard, Allan, Johansen, Kasper, Kyhl, Bjarne Linde Norgaard, Kristian Altern Øvrehus, Niels Peter Rønnow Sand, Rolf, Steffensen, Anders, Thomassen, Bo Zerahn Dominican Republic: Alfredo Perez Ecuador: Giovanni Alejandro Escorza Velez, Mayra Sanchez Velez Egypt: Islam Shawky Abdel Aziz, Mahasen, Abougabal, Taghreed, Ahmed, Adel, Allam, Ahmed, Asfour, Mona, Hassan, Alia, Hassan, Ahmed, Ibrahim, Sameh, Kaffas, Ahmed, Kandeel, Mohamed Mandour Ali, Ahmad, Mansy, Hany, Maurice, Sherif, Nabil, Mahmoud Shaaban El Salvador: Ana Camila Flores Estonia: Anne Poksi Finland: Juhani Knuuti, Velipekka, Kokkonen, Martti, Larikka, Valtteri Uusitalo France: Matthieu Bailly, Samuel, Burg, Jean-François, Deux, Vincent, Habouzit, Fabien, Hyafil, Olivier, Lairez, Franck, Proffit, Hamza, Regaieg, Laure, Sarda-Mantel, Schneider Ghana: Harold Ayetey Greece: George Angelidis, Vania Tacher Germany: Roman P., Aikaterini, Archontaki, Sofia, Chatziioannou, Ioannis, Datseris, Christina, Fragkaki, Panagiotis, Georgoulias, Sophia, Koukouraki, Maria, Koutelou, Eleni, Kyrozi, Evangelos, Repasos, Petros, Stavrou, Pipitsa Valsamaki Guatemala: Carla Gonzalez, Goleat Gutierrez Honduras: Alejandro Maldonado Hungary: Klara Buga, Ildiko, Garai, Pál, Maurovich-Horvat, Erzsébet, Schmidt, Balint, Szilveszter, Edit Várady India: Nilesh Banthia, Jinendra Kumar Bhagat, Rishi, Bhargava, Vivek, Bhat, Mona, Bhatia, Partha, Choudhury, Vijay Sai Chowdekar, Aparna, Irodi, Shashank, Jain, Elizabeth, Joseph, Sukriti, Kumar, Prof Dr Girijanandan Mahapatra, Deepanjan, Mitra, Bhagwant Rai Mittal, Ahmad, Ozair, Chetan, Patel, Tapan, Patel, Ravi, Patel, Shivani, Patel, Sudhir, Saxena, Shantanu, Sengupta, Santosh, Singh, Bhanupriya, Singh, Ashwani, Sood, Atul Verma Indonesia: Erwin Affandi, Padma Savenadia Alam, Edison, Edison, Gani, Gunawan, Habusari, Hapkido, Basuki, Hidayat, Aulia, Huda, Anggoro Praja Mukti, Djoko, Prawiro, Erwin Affandi Soeriadi, Hilman Syawaluddin Iraq: Amjed Albadr Islamic Republic of Iran: Majid Assadi, Farshad, Emami, Golnaz, Houshmand, Majid, Maleki, Maryam Tajik Rostami, Seyed Rasoul Zakavi Israel: Eed Abu Zaid, Svetlana, Agranovich, Yoav, Arnson, Rachel, Bar-Shalom, Alex, Frenkel, Galit, Knafo, Rachel, Lugassi, Israel Shlomo Maor Moalem, Maya, Mor, Noam, Muskal, Sara, Ranser, Aryeh Shalev Jamaica: Dainia Baugh, Duane, Chambers, Ernest, Madu, Felix Nunura Japan: Hiroshi Asano, Chimura Misato Chimura, Shinichiro, Fujimoto, Koichiro, Fujisue, Tomohisa, Fukunaga, Yoshimitsu, Fukushima, Kae, Fukuyama, Jun, Hashimoto, Yasutaka, Ichikawa, Nobuo, Iguchi, Masamichi, Imai, Anri, Inaki, Hayato, Ishimura, Satoshi, Isobe, Toshiaki, Kadokami, Takao, Kato, Takashi, Kudo, Shinichiro, Kumita, Hirotaka, Maruno, Hiroyuki, Mataki, Masao, Miyagawa, Ryota, Morimoto, Masao, Moroi, Shigeki, Nagamachi, Kenichi, Nakajima, Tomoaki, Nakata, Ryo, Nakazato, Mamoru, Nanasato, Masanao, Naya, Takashi, Norikane, Yasutoshi, Ohta, Satoshi, Okayama, Atsutaka, Okizaki, Yoichi, Otomi, Hideki, Otsuka, Masaki, Saito, Sakata Yasushi Sakata, Masayoshi, Sarai, Daisuke, Sato, Shinya, Shiraishi, Yoshinobu, Suwa, Kentaro, Takanami, Kazuya, Takehana, Junichi, Taki, Nagara, Tamaki, Yasuyo, Taniguchi, Hiroki, Teragawa, Nobuo, Tomizawa, Kenichi, Tsujita, Kyoko, Umeji, Yasushi, Wakabayashi, Shinichiro, Yamada, Shinya, Yamazaki, Tatsuya Yoneyama Jordan: Mohammad Rawashdeh Kazakhstan: Daultai Batyrkhanov, Tairkhan Dautov Kenya: Khalid Makhdomi, Kevin Ombati Kuwait: Faridah Alkandari, Masoud Garashi Lao People's Democratic Republic: Tchoyoson Lim Coie, Sonexay Rajvong Latvia: Artem Kalinin, Marika Kalnina Lebanon: Mohamad Haidar Lithuania: Renata Komiagiene, Giedre, Kviecinskiene, Mindaugas, Mataciunas, Karim Malta: Luise Reichmuth, Donatas Vajauskas Luxembourg: Christian Picard Malaysia: Noor Khairiah A., Anthony Samuel Mauritius: Mohammad Aaftaab Allarakha, Ambedhkar Shantaram Naojee Mexico: Erick Alexanderson-Rosas, Erika, Barragan, Alejandro Becerril González-Montecinos, Manuel, Cabada, Daniel Calderon Rodriguez, Isabel, Carvajal-Juarez, Violeta, Cortés, Filiberto, Cortés, Erasmo De La Peña, Manlio, Gama-Moreno, Luis, González, Nelsy Gonzalez Ramírez, Moisés, Jiménez-Santos, Luis, Matos, Edgar, Monroy, Martha, Morelos, Mario, Ornelas, Jose Alberto Ortga Ramirez, Andrés, Preciado-Anaya, Óscar Ulises Preciado-Gutiérrez, Adriana Puente Barragan, Sandra Graciela Rosales Uvera, Sigelinda, Sandoval, Miguel Santaularia Tomas, Sierra-Galan, Lilia M., Silvia, Siu, Enrique, Vallejo, Mario Valles Monaco: Marc Faraggi Mongolia: Erdenechimeg Sereegotov Montenegro: Srdja Ilic Morocco: Nozha Ben-Rais, Nadia Ismaili Alaoui, Sara Taleb Myanmar: Khin Pa Pa Myo, Phyo Si Thu Nepal: Ram Kumar Ghimire, Bijoy Rajbanshi Netherlands: Peter Barneveld, Andor, Glaudemans, Jesse, Habets, Klaas Pieter Koopmans, Jeroen, Manders, Stefan, Pool, Arthur, Scholte, Asbjørn, Scholtens, Riemer, Slart, Paul, Thimister, Erik-Jan Van Asperen, Niels, Veltman, Derk, Verschure, Nils Wagenaar New Zealand: John Edmond, Chris, Ellis, Kerryanne, Johnson, Ross, Keenan, Shaw Hua (Anthony) Kueh, Christopher, Occleshaw, Alexander, Sasse, Andrew, To, Niels Van Pelt, Calum Young Nicaragua: Teresa Cuadra, Hector Bladimir Roque Vanegas Niger: Idrissa Adamou Soli, Djibrillou Moussa Issoufou Nigeria: Tolulope Ayodele, Chibuzo, Madu, Yetunde Onimode Norway: Elen Efros-Monsen, Signe Helene Forsdahl, Jenni-Mari Hildre Dimmen, Arve, Jørgensen, Isabel, Krohn, Pål, Løvhaugen, Anders Tjellaug Bråten Oman: Humoud Al Dhuhli, Faiza Al Kindi, Naeema, Al-Bulushi, Zabah, Jawa, Naima Tag Pakistan: Muhammad Shehzad Afzal, Shazia, Fatima, Muhammad Numair Younis, Musab, Riaz, Mohammad Saadullah Panama: Yariela Herrera Papua New Guinea: Dora Lenturut-Katal Paraguay: Manuel Castillo Vázquez, José Ortellado People's Republic of Bangladesh: Afroza Akhter People's Republic of China: Dianbo Cao, Stephen, Cheung, Dai, Xu, Lianggeng, Gong, Dan, Han, Yang, Hou, Caiying, Li, Tao, Li, Dong, Li, Sijin, Li, Jinkang, Liu, Hui, Liu, Bin, Lu, Ming Yen Ng, Kai, Sun, Gongshun, Tang, Jian, Wang, Ximing, Wang, Zhao-Qian, Wang, Yining, Wang, Yifan, Wang, Jiang, Wu, Zhifang, Wu, Liming, Xia, Jiangxi, Xiao, Lei, Xu, Youyou, Yang, Yin, Wu, Jianqun, Yu, Yuan, Li, Tong, Zhang, Longjiang, Zhang, Yong-Gao, Zhang, Xiaoli, Zhang, Li Zhu Peru: Ana Alfaro Philippines: Paz Abrihan, Asela, Barroso, Eric, Cruz, Marie Rhiamar Gomez, Vincent Peter Magboo, John Michael Medina, Jerry, Obaldo, Davidson, Pastrana, Christian Michael Pawhay, Alvin, Quinon, Jeanelle Margareth Tang, Bettina, Tecson, Kristine Joy Uson, Mila Uy Poland: Magdalena Kostkiewicz, Jolanta Kunikowska Portugal: Nuno Bettencourt, Guilhermina, Cantinho, Antonio Ferreira Qatar: Ghulam Syed Republic of Ireland: Samer Arnous, Said, Atyani, Angela, Byrne, Tadhg, Gleeson, David, Kerins, Conor, Meehan, David, Murphy, Mark, Murphy, John, Murray, Julie O'Brien Republic of Korea: Ji-In Bang, Henry, Bom, Sang-Geon, Cho, Chae Moon Hong, Su Jin Jang, Yong Hyu Jeong, Won Jun Kang, Ji-Young, Kim, Jaetae, Lee, Chang Kyeong Namgung, Young, So, Kyoung Sook Won Republic of North Macedonia: Venjamin Majstorov, Marija Vavlukis Republic of Slovenia: Barbara Gužic Salobir, Monika Štalc Romania: Theodora Benedek, Imre, Benedek, Raluca, Mititelu, Claudiu Adrian Stan Russian Federation: Alexey Ansheles, Olga, Dariy, Olga, Drozdova, Nina, Gagarina, Vsevolod Milyevich Gulyaev, Irina, Itskovich, Anatoly, Karalkin, Alexander, Kokov, Ekaterina, Migunova, Viktor, Pospelov, Daria, Ryzhkova, Guzaliya, Saifullina, Svetlana, Sazonova, Vladimir, Sergienko, Irina, Shurupova, Tatjana, Trifonova, Wladimir Yurievich Ussov, Margarita, Vakhromeeva, Nailya, Valiullina, Konstantin, Zavadovsky, Kirill Zhuravlev Saudi Arabia: Mirvat Alasnag, Subhani Okarvi Serbia: Dragana Sobic Saranovic Singapore: Felix Keng, Jia Hao Jason See, Ramkumar, Sekar, Min Sen Yew Slovak Republic: Andrej Vondrak South Africa: Shereen Bejai, George, Bennie, Ria, Bester, Gerrit, Engelbrecht, Osayande, Evbuomwan, Harlem, Gongxeka, Magritha Jv Vuuren, Mitchell, Kaplan, Purbhoo, Khushica, Hoosen, Lakhi, Lizette, Louw, Nico, Malan, Katarina, Milos, Moshe, Modiselle, Stuart, More, Mathava, Naidoo, Leonie, Scholtz, Mboyo Vangu Spain: Santiago Aguadé-Bruix, Isabel, Blanco, Antonio, Cabrera, Alicia, Camarero, Irene, Casáns-Tormo, Hug, Cuellar-Calabria, Albert, Flotats, Maria Eugenia Fuentes Cañamero, María Elia García, Amelia, Jimenez-Heffernan, Rubén, Leta, Javier Lopez Diaz, Luis, Lumbreras, Juan Javier Marquez-Cabeza, Francisco, Martin, Anxo Martinez de Alegria, Francisco, Medina, Maria Pedrera Canal, Virginia, Peiro, Virginia, Pubul-Nuñez, Juan Ignacio Rayo Madrid, Cristina Rodríguez Rey, Ricardo Ruano Perez, Joaquín, Ruiz, Gertrudis Sabatel Hernández, Ana, Sevilla, Nahla Zeidán Sri Lanka: Damayanthi Nanayakkara, Chandraguptha Udugama Sweden: Magnus Simonsson Switzerland: Hatem Alkadhi, Ronny Ralf Buechel, Peter, Burger, Luca, Ceriani, Bart De Boeck, Christoph, Gräni, Alix Juillet de Saint Lager Lucas, Kamani, Christel H., Nadine, Kawel-Boehm, Robert, Manka, Prior, John O., Axel, Rominger, Jean-Paul Vallée Thailand: Benjapa Khiewvan, Teerapon, Premprabha, Tanyaluck Thientunyakit Tunisia: Ali Sellem Turkey: Kemal Metin Kir, Haluk Sayman Uganda: Mugisha Julius Sebikali, Zerida Muyinda Ukraine: Yaroslav Kmetyuk, Pavlo, Korol, Olena, Mykhalchenko, Volodymyr, Pliatsek, Maryna Satyr United Arab Emirates: Batool Albalooshi, Mohamed Ismail Ahmed Hassan United Kingdom: Jill Anderson, Punit, Bedi, Thomas, Biggans, Anda, Bularga, Russell, Bull, Rajesh, Burgul, John-Paul, Carpenter, Duncan, Coles, David, Cusack, Aparna, Deshpande, John, Dougan, Timothy, Fairbairn, Alexia, Farrugia, Deepa, Gopalan, Alistair, Gummow, Prasad Guntur Ramkumar, Mark, Hamilton, Mark, Harbinson, Thomas, Hartley, Benjamin, Hudson, Nikhil, Joshi, Michael, Kay, Andrew, Kelion, Azhar, Khokhar, Jamie, Kitt, Ken, Lee, Chen, Low, Sze Mun Mak, Ntouskou, Marousa, Jon, Martin, Elisa, Mcalindon, Leon, Menezes, Gareth, Morgan-Hughes, Alastair, Moss, Anthony, Murray, Edward, Nicol, Dilip, Patel, Charles, Peebles, Francesca, Pugliese, Jonathan Carl Luis Rodrigues, Christopher, Rofe, Nikant, Sabharwal, Rebecca, Schofield, Thomas, Semple, Naveen, Sharma, Peter, Strouhal, Deepak, Subedi, William, Topping, Katharine, Tweed, Jonathan Weir-Mccall United States of America: Suhny Abbara, Taimur, Abbasi, Brian, Abbott, Shady, Abohashem, Sandra, Abramson, Tarek, Al-Abboud, Mouaz, Al-Mallah, Omar, Almousalli, Karthikeyan, Ananthasubramaniam, Mohan Ashok Kumar, Jeffrey, Askew, Lea, Attanasio, Mallory, Balmer-Swain, Bayer, Richard R., Adam, Bernheim, Sabha, Bhatti, Erik, Bieging, Ron, Blankstein, Stephen, Bloom, Sean, Blue, David, Bluemke, Andressa, Borges, Kelley, Branch, Paco, Bravo, Jessica, Brothers, Matthew, Budoff, Renée, Bullock-Palmer, Angela, Burandt, Burke, Floyd W., Kelvin, Bush, Candace, Candela, Elizabeth, Capasso, Joao, Cavalcante, Donald, Chang, Saurav, Chatterjee, Yiannis, Chatzizisis, Michael, Cheezum, Tiffany, Chen, Jennifer, Chen, Marcus, Chen, Andrew, Choi, James, Clarcq, Ayreen, Cordero, Matthew, Crim, Sorin, Danciu, Bruce, Decter, Nimish, Dhruva, Neil, Doherty, Rami, Doukky, Anjori, Dunbar, William, Duvall, Rachael, Edwards, Kerry, Esquitin, Husam, Farah, Emilio, Fentanes, Maros, Ferencik, Daniel, Fisher, Daniel, Fitzpatrick, Cameron, Foster, Tony, Fuisz, Michael, Gannon, Lori, Gastner, Myron, Gerson, Brian, Ghoshhajra, Alan, Goldberg, Brian, Goldner, Jorge, Gonzalez, Rosco, Gore, Sandra, Gracia-López, Fadi, Hage, Agha, Haider, Sofia, Haider, Yasmin, Hamirani, Karen, Hassen, Mallory, Hatfield, Carolyn, Hawkins, Katie, Hawthorne, Nicholas, Heath, Robert, Hendel, Phillip, Hernandez, Gregory, Hill, Stephen, Horgan, Jeff, Huffman, Lynne, Hurwitz, Ami, Iskandrian, Rajesh, Janardhanan, Christine, Jellis, Scott, Jerome, Dinesh, Kalra, Summanther, Kaviratne, Fernando, Kay, Faith, Kelly, Omar, Khalique, Mona, Kinkhabwala, George Kinzfogl Iii, Jacqueline, Kircher, Rachael, Kirkbride, Michael, Kontos, Anupama, Kottam, Joseph, Krepp, Jay, Layer, Steven, H Lee, Jeffrey, Leppo, John, Lesser, Steve, Leung, Howard, Lewin, Diana, Litmanovich, Yiyan, Liu, Juan, Lopez-Mattei, Kathleen, Magurany, Jeremy, Markowitz, Amanda, Marn, Stephen, E Matis, Michael, Mckenna, Tony, Mcrae, Fernando, Mendoza, Michael, Merhige, David, Min, Chanan, Moffitt, Karen, Moncher, Warren, Moore, Shamil, Morayati, Michael, Morris, Mahmud, Mossa-Basha, Zorana, Mrsic, Venkatesh, Murthy, Prashant, Nagpal, Kyle, Napier, Jagat, Narula, Katarina, Nelson, Prabhjot, Nijjar, Medhat, Osman, Purvi, Parwani, Edward, Passen, Amit, Patel, Pravin, Patil, Ryan, Paul, Lawrence, Phillips, Venkateshwar, Polsani, Rajaram, Poludasu, Brian, Pomerantz, Thomas, Porter, Ryan, Prentice, Amit, Pursnani, Mark, Rabbat, Suresh, Ramamurti, Florence, Rich, Hiram Rivera Luna, Austin, Robinson, Kim, Robles, Cesar, Rodríguez, Mark, Rorie, John, Rumberger, Raymond, Russell, Philip, Sabra, Diego, Sadler, Mary, Schemmer, Joseph Schoepf, U., Samir, Shah, Nishant, Shah, Sujata, Shanbhag, Gaurav, Sharma, Steven, Shayani, Jamshid, Shirani, Pushpa, Shivaram, Steven, Sigman, Mitch, Simon, Ahmad, Slim, David, Smith, Alexandra, Smith, Prem, Soman, Aditya, Sood, Monvadi Barbara Srichai-Parsia, James, Streeter, Albert, T, Ahmed, Tawakol, Dustin, Thomas, Randall, Thompson, Tara, Torbet, Desiree, Trinidad, Shawn, Ullery, Samuel, Unzek, Seth, Uretsky, Srikanth, Vallurupalli, Vikas, Verma, Alfonso, Waller, Ellen, Wang, Parker, Ward, Gaby, Weissman, George, Wesbey, Kelly, White, David, Winchester, David, Wolinsky, Sandra, Yost, Michael Zgaljardic Uruguay: Omar Alonso, Mario, Beretta, Rodolfo, Ferrando, Miguel, Kapitan, Fernando Mut Uzbekistan: Omoa Djuraev, Gulnora Rozikhodjaeva Vietnam: Ha Le Ngoc, Son Hong Mai, and Xuan Canh Nguyen
Subjects: medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Cardiology, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, COVID-19, Cardiac imaging, Cardiovascular disease, Article, cardiac imaging, Healthcare delivery, cardiovascular disease, Intensive care, Surveys and Questionnaires, Health care, Pandemic, medicine, Humans, Pandemics, Protocol (science), business.industry, SARS-CoV-2, Non invasive, Italy, humans, pandemics, surveys and questionnaires, cardiology, Emergency medicine, Cardiology and Cardiovascular Medicine, business
Abstract: Background: In early 2020, COVID-19 massively hit Italy, earlier and harder than any other European country. This caused a series of strict containment measures, aimed at blocking the spread of the pandemic. Healthcare delivery was also affected when resources were diverted towards care of COVID-19 patients, including intensive care wards. Aim of the study: The aim is assessing the impact of COVID-19 on cardiac imaging in Italy, compare to the Rest of Europe (RoE) and the World (RoW). Methods: A global survey was conducted in May–June 2020 worldwide, through a questionnaire distributed online. The survey covered three periods: March and April 2020, and March 2019. Data from 52 Italian centres, a subset of the 909 participating centres from 108 countries, were analyzed. Results: In Italy, volumes decreased by 67% in March 2020, compared to March 2019, as opposed to a significantly lower decrease (p < 0.001) in RoE and RoW (41% and 40%, respectively). A further decrease from March 2020 to April 2020 summed up to 76% for the North, 77% for the Centre and 86% for the South. When compared to the RoE and RoW, this further decrease from March 2020 to April 2020 in Italy was significantly less (p = 0.005), most likely reflecting the earlier effects of the containment measures in Italy, taken earlier than anywhere else in the West. Conclusions: The COVID-19 pandemic massively hit Italy and caused a disruption of healthcare services, including cardiac imaging studies. This raises concern about the medium- and long-term consequences for the high number of patients who were denied timely diagnoses and the subsequent lifesaving therapies and procedures.
Published: 2021

33. Interactive History-Based Vessel Movement Prediction

Author: Philipp Last, Martin Hering-Bertram, and Lars Linsen
Subjects: Computer Networks and Communications, Movement (music), business.industry, Computer science, 02 engineering and technology, Data modeling, Visual inspection, Prediction algorithms, Artificial Intelligence, cardiovascular system, 0202 electrical engineering, electronic engineering, information engineering, Trajectory, 020201 artificial intelligence & image processing, Computer vision, Artificial intelligence, business, Collision avoidance, Data compression
Abstract: Analyzing vessel movements is indispensable for multiple tasks such as collision avoidance or route and logistics planning. We propose a novel approach for vessel movement prediction based on recorded movement data. The predicted movements including uncertainties are calculated and visualized interactively, facilitating visual inspection of relevant vessel movements within the above-mentioned scenarios.
Published: 2019

34. Predicting FinTech innovation adoption in South Africa: the case of cryptocurrency

Author: Last Mazambani and Emmanuel Mutambara
Subjects: Cryptocurrency, education.field_of_study, Financial innovation, business.industry, 05 social sciences, Population, Theory of planned behavior, General Business, Management and Accounting, FinTech, 0502 economics and business, Economics, 050211 marketing, Marketing, Emerging markets, business, education, Lagging, General Economics, Econometrics and Finance, 050203 business & management, Consumer behaviour
Abstract: Purpose Financial technology innovation within the developed world is driving financial markets, yet its adoption is lagging among consumers in emerging markets. At the same time, most African economies continue to be at the tail end of global financial innovations adoption. Given lagging consumer adoption of cryptocurrency in South Africa, the purpose of this paper is to apply the theory of planned behaviour (TPB) to predict behavioural intention to adopt cryptocurrency. Design/methodology/approach A survey instrument based on the TPB was used to collect quantitative data for predicting adoption from adult distance students at the Mancosa, Cape Town campus. For data analysis, the two-step structural equation modelling approach was used. Findings The findings indicate that attitude and perceived behavioural control positively impact the intention to adopt cryptocurrency. Subjective norm showed a negative non-significant influence. Overall, the results of the study show that the model has a good model fit and can be used to explain the theory. Research limitations/implications The results of this study may not be generalisable to the wider population as it is only based on a cross-sectional study of a sample of adult students at a single institute in South Africa. Originality/value The contribution of this paper is threefold: it is one of a few studies on the behavioural intention to adopt cryptocurrency in South Africa using the TPB model, it contributes towards the use of predictive behavioural economics models in understanding consumer behaviour critical to accelerating the adoption of financial innovations, and the results of the study also inform behaviour change strategies that can be applied by practitioners or policymakers to improve adoption. Studies of this nature may lead to the development of financial innovation in emerging markets through a nuanced understanding of consumer behaviour.
Published: 2019

35. A wall-aligned grid generator for non-linear simulations of MHD instabilities in tokamak plasmas

Author: Pamela, S., Huijsmans, G., Thornton, A. J., Kirk, A., Smith, S. F., Hoelzl, M., Eich, T., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Catarino, N., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chitarin, G., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clark, M., Clarkson, R., Clatworthy, D., Clements, C., Cleverly, M., Coad, J. P., Coates, P. A., Cobalt, A., Coccorese, V., Cocilovo, V., Coda, S., Coelho, R., Coenen, J. W., Coffey, I., Colas, L., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M. P., Craciunescu, T., Cramp, S., Craven, R., Crisanti, F., Croci, G., Croft, D., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarnecka, A., Dabirikhah, H., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., Davies, O., Davis, W., Day, C., Day, I. E., De Bock, M., de Castro, A., de la Cal, E., de la Luna, E., De Masi, G., de Pablos, J. L., De Temmerman, G., De Tommasi, G., de Vries, P., Deakin, K., Deane, J., Agostini, F. Degli, Dejarnac, R., Delabie, E., den Harder, N., Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dinca, P., D'Inca, R., Ding, B., Dittmar, T., Doerk, H., Doerner, R. P., Donne, T., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Drenik, A., Drewelow, P., Drews, P., Duckworth, Ph., Dumont, R., Dumortier, P., Dunai, D., Dunne, M., Duran, I., Durodie, F., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edmond, J., Edwards, A. M., Edwards, J., Eich, Th., Ekedahl, A., El-Jorf, R., Elsmore, C. G., Enachescu, M., Ericsson, G., Eriksson, F., Eriksson, J., Eriksson, L. G., Esposito, B., Esquembri, S., Esser, H. G., Esteve, D., Evans, B., Evans, G. E., Evison, G., Ewart, G. D., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Fasoli, A., Faustin, J. M., Fawlk, N., Fazendeiro, L., Fedorczak, N., Felton, R. C., Fenton, K., Fernades, A., Fernandes, H., Ferreira, J., Fessey, J. A., Fevrier, O., Ficker, O., Field, A., Fietz, S., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Fonnesu, N., Fontdecaba, J. M., Formisano, A., Forsythe, L., Fortuna, L., Fortuna-Zalesna, E., Fortune, M., Foster, S., Franke, T., Franklin, T., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Frigione, D., Fuchs, V., Fuller, D., Futatani, S., Fyvie, J., Gal, K., Galassi, D., Galazka, K., Galdon-Quiroga, J., Gallagher, J., Gallart, D., Galvao, R., Gao, X., Gao, Y., Garcia, J., Garcia-Carrasco, A., Garcia-Munoz, M., Gardarein, J. -L., Garzotti, L., Gaudio, P., Gauthier, E., Gear, D. F., Gee, S. J., Geiger, B., Gelfusa, M., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Ghate, M., Gherendi, M., Giacalone, J. C., Giacomelli, L., Gibson, C. S., Giegerich, T., Gil, C., Gil, L., Gilligan, S., Gin, D., Giovannozzi, E., Girardo, J. B., Giroud, C., Giruzzi, G., Gloeggler, S., Godwin, J., Goff, J., Gohil, P., Goloborod'ko, V., Gomes, R., Goncalves, B., Goniche, M., Goodliffe, M., Goodyear, A., Gorini, G., Gosk, M., Goulding, R., Goussarov, A., Gowland, R., Graham, B., Graham, M. E., Graves, J. P., Grazier, N., Grazier, P., Green, N. R., Greuner, H., Grierson, B., Griph, F. S., Grisolia, C., Grist, D., Groth, M., Grove, R., Grundy, C. N., Grzonka, J., Guard, D., Guerard, C., Guillemaut, C., Guirlet, R., Gurl, C., Utoh, H. H., Hackett, L. J., Hacquin, S., Hagar, A., Hager, R., Hakola, A., Halitovs, M., Hall, S. J., Cook, S. P. Hallworth, Hamlyn-Harris, C., Hammond, K., Harrington, C., Harrison, J., Harting, D., Hasenbeck, F., Hatano, Y., Hatch, D. R., Haupt, T. D. V., Hawes, J., Hawkes, N. C., Hawkins, J., Hawkins, P., Haydon, P. W., Hayter, N., Hazel, S., Heesterman, P. J. L., Heinola, K., Hellesen, C., Hellsten, T., Helou, W., Hemming, O. N., Hender, T. C., Henderson, M., Henderson, S. S., Henriques, R., Hepple, D., Hermon, G., Hertout, P., Hidalgo, C., Highcock, E. G., Hill, M., Hillairet, J., Hillesheim, J., Hillis, D., Hizanidis, K., Hjalmarsson, A., Hobirk, J., Hodille, E., Hogben, C. H. A., Hogeweij, G. M. D., Hollingsworth, A., Hollis, S., Homfray, D. A., Horacek, J., Hornung, G., Horton, A. R., Horton, L. D., Horvath, L., Hotchin, S. P., Hough, M. R., Howarth, P. J., Hubbard, A., Huber, A., Huber, V., Huddleston, T. M., Hughes, M., Huijsmans, G. T. A., Hunter, C. L., Huynh, P., Hynes, A. M., Iglesias, D., Imazawa, N., Imbeaux, F., Imrisek, M., Incelli, M., Innocente, P., Irishkin, M., Ivanova-Stanik, I., Jachmich, S., Jacobsen, A. S., Jacquet, P., Jansons, J., Jardin, A., Jarvinen, A., Jaulmes, F., Jednorog, S., Jenkins, I., Jeong, C., Jepu, I., Joffrin, E., Johnson, R., Johnson, T., Johnston, Jane, Joita, L., Jones, G., Jones, T. T. C., Hoshino, K. K., Kallenbach, A., Kamiya, K., Kaniewski, J., Kantor, A., Kappatou, A., Karhunen, J., Karkinsky, D., Karnowska, I., Kaufman, M., Kaveney, G., Kazakov, Y., Kazantzidis, V., Keeling, D. L., Keenan, T., Keep, J., Kempenaars, M., Kennedy, C., Kenny, D., Kent, J., Kent, O. N., Khilkevich, E., Kim, H. T., Kim, H. S., Kinch, A., King, C., King, D., King, R. F., Kinna, D. J., Kiptily, V., Kirov, K., Kirschner, A., Kizane, G., Klepper, C., Klix, A., Knight, P., Knipe, S. J., Knott, S., Kobuchi, T., Koechl, F., Kocsis, G., Kodeli, I., Kogan, L., Kogut, D., Koivuranta, S., Kominis, Y., Koeppen, M., Kos, B., Koskela, T., Koslowski, H. R., Koubiti, M., Kovari, M., Kowalska-Strzeciwilk, E., Krasilnikov, A., Krasilnikov, V., Krawczyk, N., Kresina, M., Krieger, K., Krivska, A., Kruezi, U., Ksiazek, I., Kukushkin, A., Kundu, A., Kurki-Suonio, T., Kwak, S., Kwiatkowski, R., Kwon, O. J., Laguardia, L., Lahtinen, A., Laing, A., Lam, N., Lambertz, H. T., Lane, C., Lang, P. T., Lanthaler, S., Lapins, J., Lasa, A., Last, J. R., Laszynska, E., Lawless, R., Lawson, A., Lawson, K. D., Lazaros, A., Lazzaro, E., Leddy, J., Lee, S., Lefebvre, X., Leggate, H. J., Lehmann, J., Lehnen, M., Leichtle, D., Leichuer, P., Leipold, F., Lengar, I., Lennholm, M., Lerche, E., Lescinskis, A., Lesnoj, S., Letellier, E., Leyland, M., Leysen, W., Li, L., Liang, Y., Likonen, J., Linke, J., Linsmeier, Ch., Lipschultz, B., Liu, G., Liu, Y., Lo Schiavo, V. P., Loarer, T., Loarte, A., Lobel, R. C., Lomanowski, B., Lomas, P. J., Lonnroth, J., Lopez, J. M., Lopez-Razola, J., Lorenzini, R., Losada, U., Lovell, J. J., Loving, A. B., Lowry, C., Luce, T., Lucock, R. M. A., Lukin, A., Luna, C., Lungaroni, M., Lungu, C. P., Lungu, M., Lunniss, A., Lupelli, I., Lyssoivan, A., Macdonald, N., Macheta, P., Maczewa, K., Magesh, B., Maget, P., Maggi, C., Maier, H., Mailloux, J., Makkonen, T., Makwana, R., Malaquias, A., Malizia, A., Manas, P., Manning, A., Manso, M. E., Mantica, P., Mantsinen, M., Manzanares, A., Maquet, Ph., Marandet, Y., Marcenko, N., Marchetto, C., Marchuk, O., Marinelli, M., Marinucci, M., Markovic, T., Marocco, D., Marot, L., Marren, C. A., Marshal, R., Martin, A., Martin, Y., Martin de Aguilera, A., Martinez, F. J., Martin-Solis, J. R., Martynova, Y., Maruyama, S., Masiello, A., Maslov, M., Matejcik, S., Mattei, M., Matthews, G. F., Maviglia, F., Mayer, M., Mayoral, M. L., May-Smith, T., Mazon, D., Mazzotta, C., McAdams, R., McCarthy, P. J., McClements, K. G., McCormack, O., McCullen, P. A., McDonald, D., McIntosh, S., McKean, R., McKehon, J., Meadows, R. C., Meakins, A., Medina, F., Medland, M., Medley, S., Meigh, S., Meigs, A. G., Meisl, G., Meitner, S., Meneses, L., Menmuir, S., Mergia, K., Merrigan, I. R., Mertens, Ph., Meshchaninov, S., Messiaen, A., Meyer, H., Mianowski, S., Michling, R., Middleton-Gear, D., Miettunen, J., Militello, F., Militello-Asp, E., Miloshevsky, G., Mink, F., Minucci, S., Miyoshi, Y., Mlynar, J., Molina, D., Monakhov, I., Moneti, M., Mooney, R., Moradi, S., Mordijck, S., Moreira, L., Moreno, R., Moro, F., Morris, A. W., Morris, J., Moser, L., Mosher, S., Moulton, D., Murari, A., Muraro, A., Murphy, S., Asakura, N. N., Na, Y. S., Nabais, F., Naish, R., Nakano, T., Nardon, E., Naulin, V., Nave, M. F. F., Nedzelski, I., Nemtsev, G., Nespoli, F., Neto, A., Neu, R., Neverov, V. S., Newman, M., Nicholls, K. J., Nicolas, T., Nielsen, A. H., Nielsen, P., Nilsson, E., Nishijima, D., Noble, C., Nocente, M., Nodwell, D., Nordlund, K., Nordman, H., Nouailletas, R., Nunes, I., Oberkofler, M., Odupitan, T., Ogawa, M. T., O'Gorman, T., Okabayashi, M., Olney, R., Omolayo, O., O'Mullane, M., Ongena, J., Orsitto, F., Orszagh, J., Oswuigwe, B. I., Otin, R., Owen, A., Paccagnella, R., Pace, N., Pacella, D., Packer, L. W., Page, A., Pajuste, E., Palazzo, S., Panja, S., Papp, P., Paprok, R., Parail, V., Park, M., Diaz, F. Parra, Parsons, M., Pasqualotto, R., Patel, A., Pathak, S., Paton, D., Patten, H., Pau, A., Pawelec, E., Soldan, C. Paz, Peackoc, A., Pearson, I. J., Pehkonen, S. -P., Peluso, E., Penot, C., Pereira, A., Pereira, R., Puglia, P. P. Pereira, von Thun, C. Perez, Peruzzo, S., Peschanyi, S., Peterka, M., Petersson, P., Petravich, G., Petre, A., Petrella, N., Petrzilka, V., Peysson, Y., Pfefferle, D., Philipps, V., Pillon, M., Pintsuk, G., Piovesan, P., Pires dos Reis, A., Piron, L., Pironti, A., Pisano, F., Pitts, R., Pizzo, F., Plyusnin, V., Pomaro, N., Pompilian, O. G., Pool, P. J., Popovichev, S., Porfiri, M. T., Porosnicu, C., Porton, M., Possnert, G., Potzel, S., Powell, T., Pozzi, J., Prajapati, V., Prakash, R., Prestopino, G., Price, D., Price, M., Price, R., Prior, P., Proudfoot, R., Pucella, G., Puglia, P., Puiatti, M. E., Pulley, D., Purahoo, K., Puetterich, Th., Rachlew, E., Rack, M., Ragona, R., Rainford, M. S. J., Rakha, A., Ramogida, G., Ranjan, S., Rapson, C. J., Rasmussen, J. J., Rathod, K., Ratta, G., Ratynskaia, S., Ravera, G., Rayner, C., Rebai, M., Reece, D., Reed, A., Refy, D., Regan, B., Regana, J., Reich, M., Reid, N., Reimold, F., Reinhart, M., Reinke, M., Reiser, D., Rendell, D., Reux, C., Reyes Cortes, S. D. A., Reynolds, S., Riccardo, V., Richardson, N., Riddle, K., Rigamonti, D., Rimini, F. G., Risner, J., Riva, M., Roach, C., Robins, R. J., Robinson, S. A., Robinson, T., Robson, D. W., Roccella, R., Rodionov, R., Rodrigues, P., Rodriguez, J., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Romazanov, J., Rowe, S., Rubel, M., Rubinacci, G., Rubino, G., Ruchko, L., Ruiz, M., Ruset, C., Rzadkiewicz, J., Saarelma, S., Sabot, R., Safi, E., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salmon, R., Salzedas, F., Samaddar, D., Samm, U., Sandiford, D., Santa, P., Santala, M. I. K., Santos, B., Santucci, A., Sartori, F., Sartori, R., Sauter, O., Scannell, R., Schlummer, T., Schmid, K., Schmidt, V., Schmuck, S., Schneider, M., Schoepf, K., Schworer, D., Scott, S. D., Sergienko, G., Sertoli, M., Shabbir, A., Sharapov, S. E., Shaw, A., Shaw, R., Sheikh, H., Shepherd, A., Shevelev, A., Shumack, A., Sias, G., Sibbald, M., Sieglin, B., Silburn, S., Silva, A., Silva, C., Simmons, P. A., Simpson, J., Simpson-Hutchinson, J., Sinha, A., Sipila, S. K., Sips, A. C. C., Siren, P., Sirinelli, A., Sjostrand, H., Skiba, M., Skilton, R., Slabkowska, K., Slade, B., Smith, N., Smith, P. G., Smith, R., Smith, T. J., Smithies, M., Snoj, L., Soare, S., Solano, E. R., Somers, A., Sommariva, C., Sonato, P., Sopplesa, A., Sousa, J., Sozzi, C., Spagnolo, S., Spelzini, T., Spineanu, F., Stables, G., Stamatelatos, I., Stamp, M. F., Staniec, P., Stankunas, G., Stan-Sion, C., Stead, M. J., Stefanikova, E., Stepanov, I., Stephen, A. V., Stephen, M., Stevens, A., Stevens, B. D., Strachan, J., Strand, P., Strauss, H. R., Strom, P., Stubbs, G., Studholme, W., Subba, F., Summers, H. P., Svensson, J., Swiderski, L., Szabolics, T., Szawlowski, M., Szepesi, G., Suzuki, T. T., Tal, B., Tala, T., Talbot, A. R., Talebzadeh, S., Taliercio, C., Tamain, P., Tame, C., Tang, W., Tardocchi, M., Taroni, L., Taylor, D., Taylor, K. A., Tegnered, D., Telesca, G., Teplova, N., Terranova, D., Testa, D., Tholerus, E., Thomas, J., Thomas, J. D., Thomas, P., Thompson, A., Thompson, C. -A., Thompson, V. K., Thorne, L., Thornton, A., Thrysoe, A. S., Tigwell, P. A., Tipton, N., Tiseanu, I., Tojo, H., Tokitani, M., Tolias, P., Tomes, M., Tonner, P., Towndrow, M., Trimble, P., Tripsky, M., Tsalas, M., Tsavalas, P., Jun, D. Tskhakaya, Turner, I., Turner, M. M., Turnyanskiy, M., Tvalashvili, G., Tyrrell, S. G. J., Uccello, A., Ul-Abidin, Z., Uljanovs, J., Ulyatt, D., Urano, H., Uytdenhouwen, I., Vadgama, A. P., Valcarcel, D., Valentinuzzi, M., Valisa, M., Olivares, P. Vallejos, Valovic, M., Van De Mortel, M., Van Eester, D., Van Renterghem, W., van Rooij, G. J., Varje, J., Varoutis, S., Vartanian, S., Vasava, K., Vasilopoulou, T., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Rinati, G. Verona, Veshchev, E., Vianello, N., Vicente, J., Viezzer, E., Villari, S., Villone, F., Vincenzi, P., Vinyar, I., Viola, B., Vitins, A., Vizvary, Z., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vora, N., Vu, T., Pires de Sa, W. W., Wakeling, B., Waldon, C. W. F., Walkden, N., Walker, M., Walker, R., Walsh, M., Wang, E., Wang, N., Warder, S., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Weckmann, A., Weiland, J., Weisen, H., Weiszflog, M., Wellstood, C., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Widdowson, A. M., Wiesen, S., Wilkinson, J., Williams, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wilson, J., Wischmeier, M., Withenshaw, G., Withycombe, A., Witts, D. M., Wood, D., Wood, R., Woodley, C., Wray, S., Wright, J., Wright, J. C., Wu, J., Wukitch, S., Wynn, A., Xu, T., Yadikin, D., Yanling, W., Yao, L., Yavorskij, V., Yoo, M. G., Young, C., Young, D., Young, I. D., Young, R., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zarins, A., Zastrow, K. D., Zerbini, M., Zhang, W., Zhou, Y., Zilli, E., Zoita, V., Zoletnik, S., Zychor, I., Magneto-Hydro-Dynamic Stability of Fusion Plasmas, Science and Technology of Nuclear Fusion, JET Contributors, MAST Team, and JOREK Team
Subjects: fusion, Tokamak, General Physics and Astronomy, Computational fluid dynamics, grid, 01 natural sciences, Instability, 010305 fluids & plasmas, law.invention, Physics::Plasma Physics, law, 0103 physical sciences, elm, Aerospace engineering, 010306 general physics, Aerospace, tokamak, Physics, business.industry, mhd, edge turbulence, Plasma, stability, Grid, instability, Hardware and Architecture, Mesh generation, Magnetohydrodynamics, business, reduced mhd
Abstract: Block-structured mesh generation techniques have been well addressed in the CFD community for automobile and aerospace studies, and their applicability to magnetic fusion is highly relevant, due to the complexity of the plasma-facing wall structures inside a tokamak device. Typically applied to non-linear simulations of MHD instabilities relevant to magnetically confined fusion, the JOREK code was originally developed with a 2D grid composed of isoparametric bi-cubic Bezier finite elements, that are aligned to the magnetic equilibrium of tokamak plasmas (the third dimension being represented by Fourier harmonics). To improve the applicability of these simulations, the grid-generator has been generalised to provide a robust extension method, using a block-structured mesh approach, which allows the simulations of arbitrary domains of tokamak vacuum vessels. Such boundary-aligned grids require the adaptation of boundary conditions along the edge of the new domain. Demonstrative non-linear simulations of plasma edge instabilities are presented to validate the robustness of the new grid, and future potential physics applications for tokamak plasmas are discussed. The methods presented here may be of interest to the wider community, beyond tokamak physics, wherever imposing arbitrary boundaries to quadrilateral finite elements is required. (C) 2019 Elsevier B.V. All rights reserved.
Published: 2019

36. Multi‐institutional analysis of outcomes following transoral surgery for HPV‐positive oropharyngeal squamous cell carcinoma in elderly patients

Author: Ryan S. Jackson, Stephanie Chen, Aisling Last, Amish Khan, Dorina Kallogjeri, Kathryn M. Van Abel, Eric J. Moore, and Patrik Pipkorn
Subjects: Male, medicine.medical_specialty, Population, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Stage (cooking), 030223 otorhinolaryngology, education, Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, education.field_of_study, business.industry, Incidence (epidemiology), Papillomavirus Infections, Head and neck cancer, Age Factors, Odds ratio, medicine.disease, Comorbidity, Confidence interval, Survival Rate, Oropharyngeal Neoplasms, Treatment Outcome, Otorhinolaryngology, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Female, Transoral surgery, business
Abstract: BACKGROUND The incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) is rising, even in elderly patients. The outcomes of transoral surgery (TOS) in this population are not entirely known. METHODS A retrospective review was performed at two institutions from October 2003 to September 2016 on patients 70 years or older with HPV-related OPSCC treated with TOS. RESULTS A total of 75 patients were included with a mean age of 74 years (70-87 years). At a median follow-up of 35.7 months, 3-year overall survival was 81.5% and disease-specific survival was 94.3%. Advanced cT stage (odds ratio, 2.74; 95% confidence interval, 1.13-6.64) negatively impacted OS. Conjunctive consolidation was performed to create a staging system with patients older than 80 years, severe comorbidity, and cT3-4 having worse survival. CONCLUSIONS Elderly patients with HPV-related OPSCC treated with TOS have excellent survival and therefore should not be excluded from such therapy based on age alone.
Published: 2019

37. Redefining Community: Community Radio Licencing in Zimbabwe at Crossroads

Author: Last Alfandika and Sarah Kimberly Muchetwa
Subjects: Service (business), business.industry, Communication, 05 social sciences, 050801 communication & media studies, 0506 political science, Broadcasting system, Promulgation, 0508 media and communications, Broadcasting (networking), 050602 political science & public administration, Community radio, Telecommunications, business
Abstract: The promulgation of the Broadcasting Service Act (BSA), which contains a three-tier model of the broadcasting system, was supposed to revolutionise the broadcasting media sphere in Zimbabwe. It was...
Published: 2019

38. Therapie des Antiphosphoplidsyndrom (APS) mit DOAK

Author: Edelgard Lindhoff-Last, Sebastian Schellong, U. Scholz, C. Kalka, Markus Stücker, Rupert Bauersachs, and Johannes Oldenburg
Subjects: Gynecology, 030207 dermatology & venereal diseases, 03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, business.industry, medicine, 030204 cardiovascular system & hematology, Cardiology and Cardiovascular Medicine, business, Anti phospholipid antibodies
Abstract: ZusammenfassungDas Antiphospholipid-Syndrom ist eine der schwerwiegendsten thrombophilen Störungen, die nicht nur zu rezidivierenden venösen, sondern auch zu arteriellen Thromboembolien sowie Schwangerschaftskomplikationen führen kann. Zusammen mit dem klinischen Bild ist das APS durch spezifische Laborbefunde charakterisiert: 1. Lupus Antikoagulans (LA), 2. Anticardiolipin-Antikörper (ACA), 3. β2-Glykoprotein I-Antikörper (β2GPI-AK). Alle Testergebnisse müssen nach 12 Wochen bestätigt werden. Sind alle drei Testgruppen positiv, besteht das höchste thrombotische Risiko. Beachtet werden muss, dass LA-Tests unter UFH, VKA oder DOAKs falsch positiv ausfallen können; bei DOAKs scheint die Zugabe von Absorbern nach Blutentnahme zuverlässige Ergebnisse zu liefern.Eine Vergleichsstudie (TRAPS) zwischen VKA und dem DOAK Rivaroxaban mit ausschliesslich 3-fach positiven Hochrisiko-Patienten wurde vorzeitig abgebrochen, wegen erhöhter Ereignisraten unter Rivaroxaban [19 % zumeist arterielle Ereignisse versus 3 % unter Warfarin (HR 7.4; 1.7–32.9)]. Ein daraufhin herausgegebener Rote-Hand-Brief warnt vor der Anwendung von DOAKs bei Patienten mit APS, insbesondere bei Hoch-Risiko- (3-fach positiven) Patienten, und empfiehlt die Überprüfung einer laufenden DOAK-Therapie und eine mögliche Umstellung auf VKA, insbesondere bei Hoch-Risiko-Patienten. Als Fazit soll 1. bei klinischem Verdacht eine sorgfältige APS-Diagnostik erfolgen. Viele Patienten haben aufgrund von inadäquater Diagnostik wahrscheinlich gar kein APS und können bei venöser Thromboembolie adäquat ein DOAK erhalten.2. Bei einfach- oder zweifach-positiven Antiphospholipid-AK Tests ohne LA besteht ein vergleichbar niedriges Thromboserisiko; auch hier kann möglicherweise ebenfalls mit DOAKs behandelt werden, wenn venöse Thrombosen vorliegen – ausreichende Daten liegen noch nicht vor, aber Metaanalysen legen dies nahe. 3. Patienten mit Positivität in allen 3 APS-Tests und APS-Patienten mit arteriellen Thromboembolien haben ein sehr hohes Risiko. Die TRAPS-Studie zeigt, dass diese Patienten nicht mit DOAKs, sondern mit einem VKA behandelt werden sollen.
Published: 2019

39. Moderne Therapie tiefer Venenthrombosen und der Lungenarterienembolie

Author: J Renczes and E Lindhoff-Last
Subjects: Gynecology, medicine.medical_specialty, business.industry, Deep vein, 030204 cardiovascular system & hematology, medicine.disease, Thrombosis, Pulmonary embolism, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Internal Medicine, medicine, 030212 general & internal medicine, business, Venous thromboembolism
Abstract: Die Virchow-Trias ist seit 100 Jahren bekannt. Die Entwicklung der therapeutischen Moglichkeiten in dieser Zeit war enorm. Heute ist die Antikoagulation viel differenzierter. Vier neue orale Substanzen haben die klassische Behandlung mit Vitamin-K-Antagonisten in der Angiologie abgelost. Eine standardisierte Dosis ist moglich. Das Monitoring der Gerinnungsparameter entfallt, aber die Kontrolle der Nierenfunktion wird wichtig. Direkte orale Antikoagulanzien sind fur die Behandlung der venosen Thrombosen und Lungenarterienembolie zugelassen, bisher allerdings nicht in der Schwangerschaft oder bei Kindern. Schwere, insbesondere intrazerebrale, Blutungskomplikationen sind seltener. Die Inzidenz der venosen Thromboembolien ist weiterhin hoch. Eine besondere Bedeutung kommt hierbei der Adipositas und den Tumorleiden zu. Der „therapeutische Pakt“ mit dem Patienten erfordert von uns Arzten das Beherrschen der „sprechenden Medizin“.
Published: 2019

40. Shorter Incubation Times for Detecting Multi-drug Resistant Bacteria in Patient Samples: Defining Early Imaging Time Points Using Growth Kinetics and Total Laboratory Automation

Author: Irene Burckhardt, Katharina Last, and Stefan Zimmermann
Subjects: Methicillin-Resistant Staphylococcus aureus, 0301 basic medicine, Time Factors, Growth kinetics, Multi drug resistant bacteria, 030106 microbiology, Clinical Biochemistry, Chromogenic media, medicine.disease_cause, Vancomycin-Resistant Enterococci, Workflow, Incubation period, Microbiology, 03 medical and health sciences, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, medicine, Humans, In patient, Laboratory automation, Incubation, Automation, Laboratory, Colony-forming unit, business.industry, Biochemistry (medical), Rectum, General Medicine, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Methicillin-resistant Staphylococcus aureus, Multi-drug resistant gram-negative bacteria, Kinetics, Clinical Microbiology, 030104 developmental biology, Staphylococcus aureus, Original Article, business
Abstract: Background The transition from manual processing of patient samples to automated workflows in medical microbiology is challenging. Although automation enables microbiologists to evaluate all samples following the same incubation period, the essential incubation times have yet to be determined. We defined essential incubation times for detecting methicillin-resistant Staphylococcus aureus (MRSA), multi-drug resistant gram-negative bacteria (MDRGN), and vancomycin-resistant enterococci (VRE). Methods We monitored the growth kinetics of MRSA, MDRGN, and VRE between two and 48 hours on chromogenic media to establish the time points of first growth, single colony appearance, and typical morphology for 102, 104, 106, and 108 colony forming units/mL. Subsequently, we imaged plates inoculated with 778 patient samples after 20, 24, and 36 hours. Results The first growth, single colony appearance, and typical morphology time points were inoculum-dependent. First growth appeared after 6–18 hours, 4–18 hours, and 8–48 hours for MRSA, MDRGN, and VRE, respectively, and single colonies appeared at 12–18 hours, 6–20 hours, and 12–48 hours, respectively. Typical morphology was visible at 14–22 hours and 12–48 hours for MRSA and VRE, but was not determined for MDRGN. By examining patient samples, ≥98% of MRSA and MDRGN were visible 20 hours after the start of incubation. Following 24 hours of incubation, only 79.5% of VRE were clearly visible on the respective plates. Conclusions An incubation time of 20 hours is sufficient for detecting MRSA and MDRGN. VRE growth is much slower and requires additional imaging after 36 hours.
Published: 2019

41. Cochrane's Linked Data Project: How it Can Advance our Understanding of Surrogate Endpoints

Author: Chris Mavergames, Deirdre Beecher, Lorne A. Becker, A. Last, and A. Ali
Subjects: Metadata, medicine.medical_specialty, business.industry, Surrogate endpoint, Health Policy, MEDLINE, General Medicine, Linked data, 03 medical and health sciences, Issues, ethics and legal aspects, 0302 clinical medicine, Vocabulary, Controlled, Database Management Systems, Humans, Medicine, 030212 general & internal medicine, business, Intensive care medicine, Biomarkers, 030217 neurology & neurosurgery, Semantic Web
Abstract: Cochrane has developed a linked data infrastructure to make the evidence and data from its rich repositories more discoverable to facilitate evidence-based health decision-making. These annotated resources can enhance the study and understanding of biomarkers and surrogate endpoints.
Published: 2019

42. Artificial Intelligence Methods for Software Engineering

Author: Meir Kalech, Rui Abreu, and Mark Last
Subjects: Engineering, business.industry, business, Software engineering
Published: 2021

43. The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau

Author: David McGregor, Eunice Texeira da Silva, Lynn Grignard, Adriana Goncalves, Hristina Vasileva, David Mabey, and Anna Last
Subjects: Adult, Male, medicine.medical_specialty, Mosquito Control, Adolescent, Anemia, Plasmodium falciparum, Population, Parasitemia, Logistic regression, Young Adult, Virology, Environmental health, Epidemiology, parasitic diseases, Prevalence, medicine, Humans, Guinea-Bissau, Longitudinal Studies, Insecticide-Treated Bednets, Malaria, Falciparum, Artemisinin, Child, education, Aged, education.field_of_study, biology, business.industry, Infant, Articles, Middle Aged, medicine.disease, biology.organism_classification, Cross-Sectional Studies, Infectious Diseases, Child, Preschool, Female, Parasitology, business, Malaria, medicine.drug
Abstract: Distribution of long-lasting insecticide-treated nets (LLINs), passive detection and treatment with artemisinin-based combination therapy (ACT), and intermittent preventive treatment in pregnancy (IPTp) are the mainstay malaria control measures of Guinea-Bissau’s national control programme. This study aimed to estimate the prevalence of Plasmodium falciparum on Bubaque, the most populous island of the country’s remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed to identify associations with P. falciparum infection. Four hundred four persons (aged 6 months–79 years, median 17 years) were enrolled in the study. The prevalence of P. falciparum parasitemia was 5.8% by RDT (95% CI: 3.55–9.33) and 16.9% by qPCR (95% CI: 13.09–21.71). The prevalence of anemia was 74.3% (95% CI: 69.04–78.85) as defined by the WHO criteria. All sampled houses were found to have open eaves; 99.5% of the surveyed population reported sleeping under a bednet (95% CI: 97.8–99.9). Although reported LLIN use is high, there remains an appreciable prevalence of malaria, suggesting that transmission is ongoing and further tools are required to reduce the burden of the disease.
Published: 2021

44. An Error Analysis Toolkit for Binned Counting Experiments

Author: Messerly, B., Fine, R., Olivier, A., Dar, Z. Ahmad, Akbar, F., Ascencio, M. V., Bashyal, A., Bellantoni, L., Bercellie, A., Bonilla, J. L., Caceres, G., Cai, T., Carneiro, M. F., Díaz, G. A., Felix, J., Fields, L., Filkins, A., Ghosh, A., Gilligan, S., Gran, R., Haider, H., Harris, D. A., Henry, S., Jena, S., Jena, D., Kleykamp, J., Kordosky, M., Last, D., Lozano, A., Lu, X. -G., McFarland, K. S., Nguyen, C., Paolone, V., Perdue, G. N., Ramírez, M. A., Ray, H., Ruterbories, D., Schellman, H., Salinas, C. J. Solano, Su, H., Valencia, E., Vaughan, N. H, Yaeggy, B., Yang, K., and Zazueta, L.
Subjects: Flexibility (engineering), Standardization, business.industry, Physics, QC1-999, FOS: Physical sciences, Modular design, computer.software_genre, Extensibility, Personalization, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Histogram, Physics - Data Analysis, Statistics and Probability, Data mining, User interface, business, computer, Data Analysis, Statistics and Probability (physics.data-an), Universe (mathematics)
Abstract: We introduce the MINERvA Analysis Toolkit (MAT), a utility for centralizing the handling of systematic uncertainties in HEP analyses. The fundamental utilities of the toolkit are the MnvHnD, a powerful histogram container class, and the systematic Universe classes, which provide a modular implementation of the many universe error analysis approach. These products can be used stand-alone or as part of a complete error analysis prescription. They support the propagation of systematic uncertainty through all stages of analysis, and provide flexibility for an arbitrary level of user customization. This extensible solution to error analysis enables the standardization of systematic uncertainty definitions across an experiment and a transparent user interface to lower the barrier to entry for new analyzers.
Published: 2021

45. Expanding the spectrum of gestational alloimmune liver disease

Author: Eleanor Last, David Ketteridge, and David Moore
Subjects: medicine.medical_specialty, business.industry, Internal medicine, Pediatrics, Perinatology and Child Health, medicine, business, Gestational alloimmune liver disease, Gastroenterology
Published: 2021

46. Treatment trends among men with metastatic Castration Sensitive Prostate Cancer (mCSPC): Results from the European component of an international study

Author: P. Barata, A. Leith, A. Ribbands, R. Montgomery, M. Last, B. Arondekar, J. Ivanova, and A. Niyazov
Subjects: Oncology, medicine.medical_specialty, business.industry, Urology, Internal medicine, Component (UML), medicine, business, Castration-sensitive prostate cancer
Published: 2021

47. Treatment patterns among men with metastatic Castration Resistant Prostate Cancer (mCRPC): Results from a European international study

Author: P. Barata, A. Leith, A. Ribbands, R. Montgomery, M. Last, B. Arondekar, J. Ivanova, and A. Niyazov
Subjects: Oncology, medicine.medical_specialty, Prostate cancer, business.industry, Urology, Internal medicine, medicine, Castration resistant, business, medicine.disease
Published: 2021

48. 1232P Understanding the diagnostic and treatment landscape in EGFRm advanced non-small cell lung cancer (aNSCLC) patients with exon 20 insertion mutations (Ex20ins)

Author: H. Bailey, F. Nasirova, J. Sermon, B. Rodrigues, K. Khela, J. Hall, M.J. Last, and J. Penton
Subjects: Exon, Oncology, business.industry, Cancer research, Medicine, Hematology, Non small cell, business, Lung cancer, medicine.disease
Published: 2021

49. Direct oral anticoagulants in point-of-care monitoring: an ex-vivo study

Author: Florian J Raimann, Haitham Mutlak, Edelgard Lindhoff-Last, Anna-Lena Philipp, Matthias Klages, and Kai Zacharowski
Subjects: medicine.medical_specialty, Point-of-Care Systems, Gastroenterology, Fibrin, Dabigatran, 03 medical and health sciences, 0302 clinical medicine, Thrombin, Rivaroxaban, 030202 anesthesiology, Internal medicine, Medicine, Humans, Platelet, biology, business.industry, Anticoagulants, 030208 emergency & critical care medicine, Thrombelastography, Anesthesiology and Pain Medicine, Clotting time, Concomitant, biology.protein, Blood Coagulation Tests, business, Ex vivo, medicine.drug
Abstract: BACKGROUND Anticoagulatory activity of direct oral anticoagulants (DOACs) is not routinely measurable by point-of-care monitoring. Thus, the aim of this study was to evaluate the influence of dabigatran/rivaroxaban on point-of-care testing. METHODS Samples from 34 participants under DOAC therapy were drawn at two time points. Before ingestion and two-to-three hours afterwards. Thrombelastometric (ROTEM) and aggregometric (Multiplate) measurements were performed. Dabigatran and rivaroxaban plasma levels were determined. RESULTS Dabigatran and rivaroxaban plasma levels showed significant correlations with clotting time (CT) in EXTEM (r=0.765, P
Published: 2021

50. Is it feasible to learn research skills in addition to audit skills through clinical audit? A mixed methods study in general practice

Author: Crea Carberry, Ian Callanan, Geoff McCombe, Helen Tobin, Gerard Bury, Jason Last, and Walter Cullen
Subjects: Clinical audit, Medical education, Students, Medical, education, General Practice, Sample (statistics), Audit, Patient safety, ComputingMilieux_COMPUTERSANDEDUCATION, Medicine, Humans, Learning, Undergraduate research skills, Clinical Audit, business.industry, Significant difference, General Medicine, Curriculum design, Research skills, General practice, Original Article, Curriculum, business, Family Practice, Graduation, Education, Medical, Undergraduate
Abstract: BackgroundInvolving medical students in research in their undergraduate careers may increase the likelihood that they will be research active after graduation. To date, there has been a paucity of published research of students doing research in general practice.AimThe study aims to evaluate the impact of general practice clinical audits on early-stage graduate entry students’ audit and research self-efficacy and explore feasibility issues from the student and GP perspective.MethodsTwo student questionnaires (pre- and post-intervention), a qualitative GP survey of the 25 participating GPs and semi-structured interviews of a purposeful sample of GPs were conducted.ResultsParticipating students who completed the follow-up survey found that it had a positive educational impact (55%), increased their understanding of the audit cycle (72%) and real-world prescribing (77%). Research confidence wise, there was a statistically significant difference in the student group who completed the audit project compared to those students who did not in knowledge of the audit cycle and the difference between research and audit (p = 0.001) but not in other research skills. Ninety-six percent of responding GPs would be happy for students to do future audits in their practice but some feasibility issues similar to other research initiatives in general practice were identified.ConclusionWe found this audit initiative feasible and useful in helping students learn about audit skills, patient safety and real-world prescribing. GPs and students would benefit more if it were linked to a substantial clinical placement, focussed on a topic of interest and given protected time. Separate research projects may be needed to develop research skills confidence.
Published: 2021

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