1. Obesity as a risk factor of in-hospital outcomes in patients with endometrial cancer treated with laparoscopic surgical mode
- Author
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Katarzyna Kalandyk-Osinko, Sławomir M. Januszek, Joanna Skręt-Magierło, Marek Kluza, Wojciech Domka, Aleksandra Bolanowska, Jakub Sokolowski, Paweł Szczerba, Rafał Januszek, Tomasz Kluz, Krzysztof Piotr Malinowski, and Edyta Barnas
- Subjects
obesity ,medicine.medical_specialty ,Multivariate analysis ,Waist ,sentinel lymph node procedure ,Urology ,Body Mass Index ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,medicine ,risk factors ,Humans ,minimally invasive therapy ,total laparoscopic histerectomy ,Obesity ,Risk factor ,Abdominal obesity ,Aged ,030219 obstetrics & reproductive medicine ,business.industry ,Endometrial cancer ,Obstetrics and Gynecology ,Length of Stay ,Middle Aged ,Circumference ,medicine.disease ,Endometrial Neoplasms ,endometrial cancer ,Lymph Node Excision ,Female ,Laparoscopy ,medicine.symptom ,perioperative outcomes ,business ,Body mass index - Abstract
Objectives: Abdominal obesity is a risk factor for endometrial cancer. The negative impact of individual parameters of obesity on the procedural effects of endometrial cancer surgical treatment has been suggested. The aim of the current study was to estimate the relationship of particular parameters of obesity and in-hospital outcomes in patients treated surgically due to endometrial cancer. Material and methods: The study included 70 women treated surgically for endometrial cancer. Pre-operatively, mass, body mass index (BMI), waist circumference, waist-hip ratio and selected anatomical indices were measured. The duration of surgery, hospitalisation, and the loss of haemoglobin served as parameters of in-hospital procedure success. Also, procedural-related complications were estimated. Results: There were 37 (52.8%) obese females in the current study. They were obese patients presenting more advanced clinical stages of endometrial cancer before operation. The duration of operation (94.9 ± 21.6 min. vs. 76.1 ± 13.5 min., p < 0.0001), hospitalisation (12.4 ± 3.4 days vs. 10 ± 2.3 days, p = 0.0009) and haemoglobin loss (2.5 ± 0.9 g/dL vs. 1.9 ± 0.8 g/dL, p = 0.004) were significantly greater in obese patients. Multivariate analysis, among the independent predictors of the duration of operation, has confirmed the correlation between BMI, waist circumference and weight and the duration of hospitalisation. Waist and hip circumference and BMI coupled with external conjugate dimension and intertrochanteric distance have been linked with haemoglobin loss. The strongest correlation for the duration of operation, hospitalisation and haemoglobin loss was noticed for waist circumference (r = 0.7, r = 0.57 and r = 0.59). Conclusions: Waist circumference and BMI are strong predictors of in-hospital outcomes among patients with endometrial cancer treated via traditional surgical operation.
- Published
- 2020
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