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Ganglion cysts are benign cystic masses that occur in association with musculoskeletal structures. The aetiology of ganglion cysts is controversial; however, it is generally thought to result from myxoid degeneration of connective tissue associated with joint capsules or tendon sheaths, to which the lesions are usually attached. They may occur in any part of the extremities within muscles, menisci, tendons or bones. Hereby, we present a rare case of intra-tendinous location of a ganglion cyst of the semimembranosus tendon occurring within the tendon substance itself. To date, there have only few cases reports in the literature reviewing intra-tendinous ganglion cysts occurred in the lower limbs.

The 2010 Annual General Meeting and Scientific Meeting of the Hong Kong Society for Immunology (HKSI), Hong Kong, 17 April 2010.