1. Central nervous system involvement in acute lymphoblastic leukemia: diagnosis by immunophenotyping
- Author
-
Benigna Maria de Oliveira, Maria Luiza Silva, Marcelo Eduardo de Lima Souza, Marcos Borato Viana, Vírginia Miguel Furtado, José Márcio Barcelos, Mitiko Murao, and Camila Silva Peres Cancela
- Subjects
líquido cefalorraquidiano ,imunofenotipagem ,Pathology ,medicine.medical_specialty ,business.industry ,Lymphoblastic Leukemia ,Clinical Biochemistry ,Central nervous system ,hemic and immune systems ,leucemia linfoide aguda ,Pathology and Forensic Medicine ,Medical Laboratory Technology ,Cerebrospinal fluid ,medicine.anatomical_structure ,Immunophenotyping ,hemic and lymphatic diseases ,Immunology ,lcsh:Pathology ,medicine ,sistema nervoso central ,business ,lcsh:RB1-214 - Abstract
The central nervous system is the most commonly affected extramedullary site in acute lymphoblastic leukemia. Although morphologic evaluation of the cerebrospinal fluid has been traditionally used for diagnosing central nervous system involvement, it is a method of low sensitivity. The present study aimed at evaluating the use of immunophenotyping in the detection of blasts in the cerebrospinal fluid from children and adolescents with acute lymphoblastic leukemia.
- Published
- 2013
- Full Text
- View/download PDF