3 results on '"J. López Robles"'
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2. The First Year of the AEVD Primary Cutaneous Lymphoma Registry
- Author
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M. Morillo, P. Espinosa, Pablo L. Ortiz-Romero, Miguel Ángel Descalzo, J. López Robles, M.D. Ramón, Octavio Servitje, Yeray Peñate, Maria Teresa Estrach, S. Machan, N. Gónzalez-Romero, A. Mateu, S. Medina, Andrea Combalia, Ignacio García-Doval, Á. Flórez, Arnoldo Riquelme Pérez, Berta Ferrer, J. Bassas, I. Yanguas, Jesús Domínguez, M. Blanes, C. Muniesa, J. Mitxelena, I. Polo-Rodríguez, A. Zayas, H. Suh, Elvira Acebo, Isabel Bielsa, and Ricardo Fernández-de-Misa
- Subjects
Mycosis fungoides ,Registry ,medicine.medical_specialty ,Histology ,Lymphoma, B-Cell ,Skin Neoplasms ,CD30 ,Databases, Factual ,Dermatology ,Cutaneous lymphoma ,Pathology and Forensic Medicine ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Disease registry ,Lymphomatoid Papulosis ,medicine ,Humans ,Prospective Studies ,Registries ,Lymphomatoid papulosis ,Stage (cooking) ,business.industry ,medicine.disease ,Primary cutaneous 8-cell lymphoma ,Lymphoma ,Lymphoma, T-Cell, Cutaneous ,Cutaneous lymphoma, Linfoma cutáneo primario B, Linfomas cutáneos, Micosis fungoide, Mycosis fungoides, Primary cutaneous B-cell lymphoma, Primary cutaneous CD30-positive lymphoproliferative disorder, Registro, Registry, Trastorno linfoproliferativo primario cutáneo CD30+ ,Clinical research ,Primary cutaneous CD30-positive lymphoproliferative disorder ,Spain ,030220 oncology & carcinogenesis ,Lymphoma, Large-Cell, Anaplastic ,business - Abstract
Background and objective: Primary cutaneous lymphomas are uncommon. This article describes the Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV) and reports on the results from the first year. Patients and methods: Disease registry for patients with primary cutaneous lymphoma. The participating hospitals prospectively recorded data on diagnosis, treatment, tests, and disease stage for all patients with primary cutaneous lymphoma. A descriptive analysis was performed. Results: In December 2017, the registry contained data on 639 patients (60% male) from 16 university hospitals. The most common diagnoses, in order of frequency, were mycosis fungoides/Sezary syndrome (MF/SS) (348 cases, 55%), primary cutaneous B-cell lymphoma (CBCL) (184 cases, 29%), primary cutaneous [D30' T-cell lymphoproliferative disorder (CD30+ CLPD) (70 cases, 11%), and other types of T-cell lymphoma (37 cases, 5%). In total, 105 (16.5%) of the cases recorded were incident cases. The most common diagnosis in the MF/SS group was classic MF (77.3%). Half of the patients with MF had stage IA disease when diagnosed, and the majority were either in partial remission (32.5%) or had stable disease (33.1%). The most widely used treatments were topical corticosteroids (90.8%) and phototherapy. The most common form of primary CBCL was marginal zone lymphoma (50%). Almost all of the patients had cutaneous involvement only and nearly half had stage T1a disease. Most (76.1%) were in complete remission. The main treatments were surgery (55.4%) and radiotherapy (41.9%). The most common diagnosis in patients with CD30+ CLPD was lymphomatoid paputosis (68.8%). Most of the patients (31.4%) had stage T3b disease and half were in complete remission. The most common treatments were topical corticosteroids (68.8%) and systemic chemotherapy (32.9%). Conclusion: The characteristics of patients with primary cutaneous lymphoma in Spain do not differ from those described in other series in the literature. The registry will facilitate clinical research by the AEDV's lymphoma group. (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.
- Published
- 2018
3. Evaluation of biocontrol agro-techniques against R. solani: study of microbial communities catabolic profile modifications
- Author
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A. García-Villaraco, F. J. Gutiérrez-Mañero, J. I. Reguera-Useros, Gonzalo Sacristán-Pérez-Minayo, and D. J. López-Robles
- Subjects
education.field_of_study ,biology ,business.industry ,Inoculation ,Damping off ,Population ,Pseudomonas ,Biological pest control ,Pseudomonas fluorescens ,biology.organism_classification ,Rhizobacteria ,Biotechnology ,Rhizoctonia solani ,Horticulture ,Genetics ,Animal Science and Zoology ,business ,education ,Agronomy and Crop Science - Abstract
SUMMARYDamping off is the most common disease caused by edaphic fungi in Spanish crops, among which Rhizoctonia solani AG-4 stands out. In the present work, two possible methods of control were evaluated, incorporation of different doses of organic matter (OM; obtained from strawberry crops) and Pseudomonas fluorescens as a plant growth promoting rhizobacteria (PGPR). The highest inhibition (43% less) against the pathogen was found in the assays that used 20 g of biofumigant/kg soil. Inoculation of the P. fluorescens strain (PGPR) did not protect against the pathogen. In addition, the microbial evolution during incubation with OM was studied. For this purpose, the bacterial and fungal catabolic profiles were determined (using Biolog Eco and FF plates, respectively) as well as bacterial counts of total aerobes, Pseudomonas sp. and aminocyclopropane-1-carboxylate (ACC)-degrading populations, during OM incorporation. This agro-technique produced changes in microbial catabolic community profiles, increasing bacterial metabolic activity and minimizing metabolic diversity of micro-organisms under control with and without pathogen. As for microbial counts, aerobic and ACC-degrading populations decreased while Pseudomonas sp. population increased with OM treatments.The OM amendment applied to control the damping off caused by R. solani is viable; it is more environmentally friendly and has a lower economic cost than chemical controls and, therefore, it could serve as a component in integrated-management programmes.
- Published
- 2011
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