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Geographic and socio-economic factors combined make China particularly vulnerable to droughts. Here we review academic literature to assess publication trends on the topics of drought monitoring and early warning in China, exploring the common themes and recent advances presented. Literature searches for the 1970–2017 period were made for a range of search terms relating to drought monitoring. It was found that publications on these topics started to appear sporadically in 1989 and have increased rapidly since the early 2000s, with the rate of publication increasing over the last eight years. The scope of studies varied, often with the spatial scale considered: at the national scale, studies focused on evaluating existing indices, while new indices were developed and tested at the regional scale – relating, in general, to monitoring agricultural and meteorological droughts. At the catchment scale, novel monitoring techniques were developed, often incorporating other data types such as modelled data or soil moisture measurements. National scale operational drought monitoring in China is currently being improved and updated. However, although operational systems are discussed in the literature, there is a still a disconnect between theory and practice with the most recent advances not yet operationalised. Here, we identify the methods and approaches which can be translated from the experimental case study scale to the national operational scale.

Weakening drinking-related reward memories by blocking their reconsolidation is a potential novel strategy for treating alcohol use disorders. However, few viable pharmacological options exist for reconsolidation interference in humans. We therefore examined whether the NMDA receptor antagonising gas, Nitrous Oxide (N2O) could reduce drinking by preventing the post-retrieval restabilisation of alcohol memories in a group of hazardous drinkers. Critically, we focussed on whether prediction error (PE; a key determinant of reconsolidation) was experienced at retrieval. Sixty hazardous drinkers were randomised to one of three groups that retrieved alcohol memories either with negative PE (Retrieval + PE), no PE (Retrieval no PE) or non-alcohol memory retrieval with PE (No-retrieval +PE). All participants then inhaled 50% N2O for 30 min. The primary outcome was change in beer consumption and alcohol cue-driven urge to drink from the week preceding manipulation (baseline) to the week following manipulation (test). The manipulation did not affect drinking following the intended retrieval+/- PE conditions However, a manipulation check, using a measure of subjective surprise, revealed that the group-level manipulation did not achieve the intended differences in PE at retrieval. Assessment of outcomes according to whether alcohol-relevant PE was actually experienced at retrieval, showed N2O produced reductions in drinking in a retrieval and PE-dependent fashion. These preliminary findings highlight the importance of directly testing assumptions about memory reactivation procedures in reconsolidation research and suggest that N2O should be further investigated as a potential reconsolidation-blocking agent.

Macroinvertebrates are used more often than any other groups of organisms when assessing the environmental quality of lotic systems. In this chapter we describe the many ways macroinvertebrates are used as indicators of environmental quality—from the molecular-through the community-level of biological organization. We highlight more recent advances in the use of DNA bar coding and species traits and then describe in detail the most commonly used macroinvertebrate-based methods for assessing the quality of streams and rivers. Two exercises are provided. The first can be completed as a full day project by students or volunteers and includes a laboratory-only option. The second provides the basic background and information for a college-level senior thesis, graduate study or governmental monitoring organization.

This paper presents a novel approach for the mapping of geometric errors of machine tools and coordinate measuring machines by a single tracking interferometer. The concept is based on interferometric displacement measurements between reference points that are fixed to the base and offset points fixed to the machine head. The experimental comparison with an independent technique on a high accuracy CMM demonstrated the agreement of parameters in the sub-micron range. Thus, the method proved to be suitable for the highest accuracy demands. Furthermore, it has almost no limitation for the maximum size of the working volume. It does not require any alignment of equipment and yields a very simple data structure, which can be evaluated by the developed software with very little additional information from the operator. The method has also been tested on a large horizontal arm machine and on a smaller high precision machine tool.

Habitat assessments are an important component of most water quality evaluations in the USA. Habitat assessments are often based on an observer rating the habitat quality of a site by matching specific habitat features to written descriptions. We examined the effect that training has on reducing observer variability by using 2 separate groups of observers to assess the habitat quality at the same sites. One group received training on habitat assessments; the 2nd group conducted the assessment using the written descriptions but without training. The trained group's assessments were less variable than those of the untrained group of observers. We attribute this difference to a greater disparity among untrained observers in the interpretation of individual habitat features. However, after equal training and experience, variability of both groups' habitat assessments was not significantly different at a 2nd stream site. Finally, the variability of the habitat assessments at the 2 sites was not equal, indicati...

The prevalence of neuropathy and microangiopathy complicating diabetes mellitus led to our development of non-invasive tests of neurovascular function. On the foot dorsum of consenting normal subjects, diabetic patients, normal and streptozotocin-induced (STZ) diabetic rats, transcutaneous electrical nerve stimulation (TENS) with 1, 2, 4, 8, 16 pulses at 150 V, 0.75 ms, at 2 Hz, evokes transient cutaneous axon reflex vasodilatation measured by a laser Doppler (Periflux Pfld). This tests the integrity of both the polymodal nociceptor/primary afferent nerves and microvessels in the skin. TENS-evoked axon reflexes are reduced in diabetics (particularly with neuropathy) and progressively in rats 40-100 days after STZ administration. This could be reversed in rats by a single injection of 3 units of soluble insulin at 100 days post STZ. The microvascular endothelium and smooth muscle are tested in man by measuring vasodilatation induced by iontophoretic application of 2 mC acetylcholine (ACh) and 4 mC sodium nitroprusside (NaNP), respectively. Diabetics show reduced ACh-evoked endothelium-dependent vasodilator responses, but the direct smooth muscle (endothelium-independent) responses evoked by NaNP are not reduced. Such functional neurovascular disturbances probably underlie many complications of diabetes mellitus, and the potential for these to be reversible with appropriate therapy can now be examined with such neurovascular tests.

Increasingly competitive pressures during the past decade have caused both industrial buyers and suppliers to search for new economies and means for achieving greater profitability. Industrial wholesaler-distributors have responded with a variety of contractually based “systems” that are designed to simplify customers' purchase of supplies while ensuring distributor profits. The two main varieties of such Systems are popularly called “Blanket Orders” and ”Systems Contracts,” but the latter are more comprehensive extensions of the former. Specifically, Systems Contracts imply a total commitment by a distributor toward solving his customers' supplies problems. Such agreements typically involve a shifting of the supplies warehousing function back to the vendor, where items are then automatically reordered by plant-level users as opposed to purchasing agents. Rounding out the System is an extensive array of vendor-supplied services: 24-hour item delivery, computer-processed item usage reports, a control feature, and vendor consultation and problem solving. The Contract effectively links buyer and supplier together in a harmonious, profitable relationship.