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6,903 results on '"Izquierdo, A."'

1. PACKAGING SHIFTS TO RENEWABLE SOURCES: PRIMARY OBJECTIVES FOCUS ON SUSTAINABILITY AND SHELF LIFE

Author

Izquierdo, Jorge

Subjects
Meat industry -- Packaging, Ecological footprint, Refuse and refuse disposal, Recycling (Waste, etc.), Environmental sustainability, Seafood -- Packaging, Business, Food and beverage industries
Abstract

Consumers continue to consider sustainability when making purchasing decisions. As a result, producers of meat, poultry, and seafood products are working to reduce plastic usage, especially single-use plastic, and adopt [...]

Published
2024

2. Rasgos determinantes para la conformación de territorios solidarios en Colombia

Author

Nubia Varón Triana, Aracelly Buitrago Mejía, Patricia del Pilar Izquierdo Hernández, and Gustavo Adolfo Rubio-Rodríguez

Subjects
asociaciones productoras, economía social y solidaria, rasgos de las comunidades, sector rural, territorio solidario, Commerce, HF1-6182, Business, HF5001-6182
Abstract

Esta investigación tiene por objeto analizar los rasgos económicos, sociales y culturales que caracterizan a las organizaciones de la economía social y solidaria como determinantes para configurar territorios solidarios donde prevalezcan los principios de esta economía. La investigación es descriptiva y su enfoque es cualitativo. La población está conformada por tres asociaciones dedicadas a la producción de mangos y sus derivados en el municipio de El Espinal - Colombia. Como resultado, se evidencia que los asociados gozan de una mejor calidad de vida que sus padres; se consideran afectados por el abandono del Estado al sector rural y no participan activamente en cargos de elección popular. Se identifican problemas en vías de acceso, educación y servicios públicos. Se concluye que las características económicas, sociales y culturales son determinantes para promover la conformación de territorios solidarios en Colombia. La discusión establece una línea de investigación para determinar el papel de estos rasgos en los territorios solidarios.

Published
2023
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3. A simple and efficient method to allocate costs and benefits in energy communities

Author

David Gonzalez-Asenjo, Luis R. Izquierdo, and Javier Sedano

Subjects
energy community, prosumer, allocation, costs, fairness, efficiency, Industrial engineering. Management engineering, T55.4-60.8, Social Sciences, Commerce, HF1-6182, Business, HF5001-6182
Abstract

Purpose: Define a simple and efficient method to allocate costs and benefits in energy communities, and characterize some of its key properties. Design/methodology/approach: The approach is theoretical. We define an algorithm to allocate costs and benefits in energy communities, and derive some of its formal properties using mathematical reasoning. We also compare the proposed algorithm with several alternatives. Findings: The proposed algorithm is simple and it ensures that the resulting distribution of costs and benefits is (i) beneficial for every member of the community, (ii) efficient, (iii) fair (in a formally defined sense), (iv) smooth (small changes in the consumption or in the generation of energy cannot lead to big changes in the allocation of costs and benefits), and (v) environmentally friendly in the sense that the individual allocated cost is a strictly increasing function of individual consumption. Research limitations/implications: The properties of the proposed algorithm are satisfied for a specific type of energy community that is defined in the manuscript. Practical implications: The algorithm is easy to implement in any energy community. Social implications: The algorithm is highly relevant for any community of prosumers who are willing to exchange energy internally. It guarantees a number of desirable properties that are formally defined in the paper. Originality/value: We prove that a simple algorithm to allocate costs and benefits in energy communities guarantees the fulfilment of several desirable properties.

Published
2023
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4. Stakeholders Must Join Forces to Achieve Circularity: A circular packaging economy depends on improvements in design, recovery infrastructure and regulatory changes

Author

Izquierdo, Jorge

Subjects
Infrastructure (Economics) -- Forecasts and trends, Refuse and refuse disposal -- Forecasts and trends, Market trend/market analysis, Business, Food and beverage industries
Abstract

Packaging has always been a balancing act. Consumer packaged goods (CPG) companies must weigh cost versus performance and market appeal versus machinability. As interest in sustainable packaging has grown, brand [...]

Published
2023

5. Metaverse, a Holistic Vision of the New Virtual Reality

Author

M.-Dolores Méndez-Aparicio, Ana-Isabel Jiménez-Zarco, and Alicia Izquierdo-Yusta

Subjects
Advertising, Archetype, Avatar, Augmented reality, Difussion of Innovation Model, Extended Reality, Business, HF5001-6182
Abstract

Metaverse bursts into the media as a new marketing channel in September 2021, creating an explosion of reactions as brands join the race to be pioneers. Within a fully digital society and from a mature gaming industry, Metaverse is much more than an incubator of marketing and advertising ideas for brands, Metaverse is envisioned as a social disruption. This scenario raises three relevant questions to resolve over time: 1) Will the Metaverse finally take shape as a virtual society or, on the contrary, will it be integrated as one more channel of relationship within the context omnichannel? 2) how customers, brands and institutions are reacting to the Metaverse and 3) in any case, what transversal disruptive changes will be necessary in the new scenario of the Metaverse? From the deep and constant search for information in secondary sources (desk research methodology), this article seeks a holistic vision of the Metaverse, and its reading will allow defining specific areas of research on behavior patterns of people in this new virtual reality.

Published
2023
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6. Focus on Sustainability in Packaging Intensifies: Brand owners embrace environmentally friendly materials and practices

Author

Izquierdo, Jorge

Subjects
Sustainable development -- Reports, Ecological footprint -- Reports, Global temperature changes -- Reports, Alternative energy sources -- Reports, Business, Food and beverage industries
Abstract

Interest in sustainability continues to intensify among consumer packaged goods (CPG) companies, contract packagers, suppliers, and OEMs. In fact, sustainability is one of four key priorities identified in Challenges and [...]

Published
2023

7. Diversidad económica regional y desempeño socioeconómico en las provincias del Ecuador (período 2014-2018)

Author

Wilson Santiago Izquierdo Rodríguez and Paola Alexandra Carangui Velecela

Subjects
concentración económica, desarrollo económico, desarrollo regional, estructura económica, geografía económica, Business, HF5001-6182, Economic theory. Demography, HB1-3840
Abstract

El presente artículo tiene como objetivo estimar el efecto de la diversidad económica regional sobre las condiciones socioeconómicas en las provincias del Ecuador, tomando como referencia el período 2014-2018. La investigación es de tipo explicativa, con diseño documental, no experimental, transversal y emplea como métodos de análisis los enfoques analítico-sintético y cuantitativo-empírico. Las estimaciones econométricas efectuadas con datos de corte transversal de las 24 provincias del Ecuador, con el método de Mínimos Cuadrados Ordinarios, sugieren efectos positivos del coeficiente de especialización regional y del índice de concentración sobre la volatilidad observada en el ingreso y en el crecimiento. Así mismo, la especialización regional se asocia con una mayor tasa de pobreza, mientras que hay una relación inversa entre especialización y concentración con la tasa promedio de crecimiento de las provincias. El estudio permitió concluir, en primer lugar, que la planificación del desarrollo exige la reducción de las heterogeneidades productivas que presenta una economía como Ecuador y, en segundo lugar, que los beneficios del desarrollo sólo serán ampliamente percibidos por la población en la medida que las regiones diversifican su actividad económica.

Published
2022
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8. KPI for students satisfaction measurement as an indicator of university management

Author

Alicia Izquierdo-Yusta, Ana Isabel Jiménez-Zarco, Inés González-González, and Carmen M. Gómez-Cantó

Subjects
kpi, educación, satisfacción, estudiantes, universidad, gestión, education, satisfaction, students, university, management, Special aspects of education, LC8-6691, Business, HF5001-6182
Abstract

Currently universities need to be competitive. The current environment forces universities to design strategies where the student becomes the center of their activity. Elements such as student satisfaction become key performance indicators of the strategy, so that universities are required to establish metrics that make it possible to measure the level of performance achieved based on the objectives they had previously set. In order to verify it, through a series of dimensions that measure the satisfaction of the teaching-learning process, a scale has been proposed to measure satisfaction. To confirm the consistency of the proposed scale, the reliability and validity indicators of the same were verified. The selected sample corresponds to university students studying undergraduate and master’s degrees in the online mode. Results obtained show the importance of correctly setting the objectives and contents of the different subjects that make up the curricula of each grade, as well as the outstanding role that the teacher has in said process.

Published
2020
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9. El comportamiento de mercado como ruta de cambio en los talleres mecánicos de Tijuana Baja California

Author

Omar Valladares-Icedo and Román Izquierdo-De Dios

Subjects
taller mecánico, marketing, comportamiento de mercado, mujeres, organización, Military Science, Business, HF5001-6182
Abstract

El comportamiento del mercado es uno de los factores más analizados por los mercadólogos, en este documento se inició con investigación empírica, a partir de hallazgos en la literatura y la observación, analizando los cambios de comportamiento, en el hombre y la mujer al momento adquirir un servicio, especialmente el taller mecánico, en la ciudad de Tijuana Baja California. Los hallazgos mostraron que la empresa dedica sus esfuerzos para atender el género masculino, pero que un 30% de las mujeres atiende sus necesidades de servicio automotriz, toma las decisiones con mucho mayor rapidez, y disfruta mucho más de la compra. Existe un porcentaje menor, que se hace de un aliado hombre, para solicitar los servicios mecánicos, y deja en total libertad al aliado para que tome la decisión de compra. En contra parte, los hombres que forman el 70% de los que adquieren este servicio, argumentan las soluciones del taller, y toman con mayor difcultad la decisión de compra. El marketing utilizado en el taller genérico cumple de manera empírica con parámetros de escasa medición, y la capacitación del personal, para mejorar el servicio al cliente, es una constante a mejorar.

Published
2020
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10. Redes neurales atencionales en enfermedades neurodegenerativas: evidencias anatómico-funcionales empleando el Attention Network Test

Author

G. Izquierdo-Ayuso, Manuel Vázquez-Marrufo, and E. Sarrias-Arrabal

Subjects
03 medical and health sciences, 0302 clinical medicine, business.industry, Medicine, Neurology (clinical), business, Humanities, 030217 neurology & neurosurgery
Abstract

Resumen Introduccion Comprender las alteraciones en la anatomia y funcion del cerebro en los procesos cognitivos para las enfermedades neurodegenerativas es aun un desafio para la neurociencia actual. Desde la neurociencia experimental algunos test computarizados han sido desarrollados para mejorar nuestro conocimiento de las redes neurales involucradas en la cognicion. El Attention Network Test (ANT) permite medir la activad de las 3 redes atencionales (alerta, orientacion y funcion ejecutiva). Objetivos El principal objetivo de esta revision fue describir todas las alteraciones anatomicas y funcionales encontradas en diversas enfermedades neurologicas usando el ANT. Material y metodos Un protocolo de revision fue aplicado seleccionando estudios desde 2010 en la base de datos PubMed, que involucraban al ATN en diferentes enfermedades neurologicas. Se obtuvieron 32 articulos para esclerosis multiple, epilepsia o Parkinson entre otras enfermedades. Conclusiones Se confirman algunas de las estructuras anatomicas propuestas para el modelo de 3 grandes redes atencionales. Las estructuras mas relevantes para la red de alerta son la corteza prefrontal, las regiones parietales, el talamo y el cerebelo. El talamo es tambien relevante para la red de orientacion, junto a regiones parietales posteriores. Respecto a la red ejecutiva no depende exclusivamente de la corteza prefrontal y corteza cingulada anterior, sino tambien de estructuras subcorticales como los ganglios basales y el cerebelo y sus proyecciones hacia toda la corteza.

Published
2023
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11. Experiencia clínica de la terapia electroconvulsiva con anestesia y relajación en la Clínica Universidad de La Sabana: 2009-2017

Author

Erika Pineda Carrascal, Hollman Salamanca Dimas, Ángela Rocío Acero González, Alejandra Ayala Escudero, Juliana Izquierdo Polanco, Verónica Páez Avendaño, and Yahira Rossini Guzmán Sabogal

Subjects
03 medical and health sciences, Psychiatry and Mental health, 0302 clinical medicine, business.industry, Medicine, business, Humanities, 030217 neurology & neurosurgery, 030227 psychiatry
Abstract

Resumen Introduccion La terapia electroconvulsiva es un procedimiento efectivo y seguro, el cual se indica principalmente a pacientes con episodios depresivos tanto unipolares como bipolares, mania y esquizofrenia, cuando no responden a otros tratamientos. Objetivo Describir las propiedades demograficas, sociales y clinicas de un grupo de pacientes tratados con terapia electroconvulsiva con anestesia y relajacion (TECAR) en la Clinica Universidad de La Sabana por un periodo de 8 anos. Metodos Se revisan las bases de datos y los registros de los procedimientos desde el 1 de enero de 2009 hasta el 31 de diciembre de 2017. Se realiza un analisis con estadistica descriptiva. Resultados En este periodo se realizaron 1.322 procedimientos a 143 pacientes, el 54,5% de ellos mujeres, y con diagnostico asociado de depresion mayor en el 57% de los pacientes. El numero de tratamientos por persona fue 9,2 y en el 3,8% se presentaron complicaciones, sin que se requiriese tratamiento invasivo en ninguna de ellas. Conclusiones La terapia electroconvulsiva se aplica con seguridad a los pacientes y con parametros diversos en cuanto a edad, sexo y diagnostico mas frecuente, en comparacion con otros paises de Latinoamerica y el mundo. Es importante sumar esfuerzos en investigacion que permitan tener un panorama mas completo de las caracteristicas de su aplicacion en el pais.

Published
2023
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12. CANNABIS GETS READY FOR ITS CLOSE-UP: Despite ongoing legal hurdles, an increasingly diverse market is poised for automation

Author

Izquierdo, Jorge

Subjects
Medical marijuana -- Forecasts and trends, Marijuana industry -- Forecasts and trends, Market trend/market analysis, Business, Containers and packaging industries
Abstract

According to a recent report on the COVID-19 outlook and impact on medical marijuana, the cannabis market is poised to grow by U.S. $22.33 billion with a CAGR if over [...]

Published
2020

13. 3 STEPS FOR SUSTAINABLE PACKAGING: Every decision counts, from conception to communication

Author

Izquierdo, Jorge

Subjects
Recycling, Sustainable development, Company marketing practices, Business, Pharmaceuticals and cosmetics industries
Abstract

Regardless of where companies currently stand on the sustainability spectrum, there is always room for growth--and certainly the demand to support it. As consumer awareness of sustainable brand practices grows, [...]

Published
2020

14. Automation Overcomes Workforce and Productivity Shortfalls: With automation, CPG firms can enhance and optimise their production, storage and distribution processes, gain flexibility and improve the safety of employees

Author

Izquierdo, Jorge

Subjects
Automation -- Technology application -- Reports -- Forecasts and trends, Workers -- Reports -- Forecasts and trends -- Technology application, Labor productivity -- Reports -- Technology application -- Forecasts and trends, Mechanization -- Technology application -- Reports -- Forecasts and trends, Market trend/market analysis, Technology application, Business, Food and beverage industries
Abstract

For consumer packaged goods (CPG) manufacturers, particularly makers of tea and coffee products, hiring enough workers with the proper skill levels, maintaining productivity, and responding to the growth in e-commerce [...]

Published
2023

16. Economía artificial: una valoración crítica // Artificial Economics: A Critical Review

Author

Segismundo S. Izquierdo, Luis R. Izquierdo, José M. Galán, and José I. Santos

Subjects
economía artificial, economía computacional, economía computacional basada en agentes, artificial economics, computational economics, agent-based computational economics, Applied mathematics. Quantitative methods, T57-57.97, Mathematics, QA1-939, Business, HF5001-6182
Abstract

La economía artificial es uno de los métodos o enfoques de investigación para el estudio de sistemas socioeconómicos complejos con mayor crecimiento durante los últimos años. Este artículo presenta una visión crítica sobre sus características, su potencial y los riesgos relativos al uso de esta metodología. Para ello, encontramos útil relacionar y comparar a la economía artificial con la economía teórica más tradicional. Desde nuestro análisis, la economía teórica y la economía artificial comparten los mismos objetivos, presentan menos diferencias metodológicas de las que a primera vista pudiera parecer, y sus aproximaciones son sin duda complementarias. ------------------------------------ Artificial Economics is one of the fastest growing approaches to analyse complex socio-economic systems. In this paper we present our views on the distinguishing features of Artificial Economics and on its relation with Theoretical Economics — the field that in our opinion lies closest to Artificial Economics. In this context, we discuss various reasons why conducting research on Artificial Economics may be worthwhile, and provide general guidelines on how to go about it. Our view is that Artificial Economics and Theoretical Economics share the same goals, do not differ conceptually as much as it is sometimes perceived, and their approaches are certainly complementary.

Published
2016

17. Clinical characteristics and prognosis of myocardial infarction with non-obstructive coronary arteries: A prospective single-center study

Author

Barbara Izquierdo Coronel, Carlos Moreno Vinués, José Ramón González-Juanatey, Maria Jesus Espinosa Pascual, Javier López-Pais, Blanca Alcon Duran, Javier Muñiz García, Paula Awamleh García, Joaquín J. Alonso Martín, Carlos Gustavo Martinez Peredo, and David Galan Gil

Subjects
medicine.medical_specialty, Myocardial Infarction, Coronary Artery Disease, 030204 cardiovascular system & hematology, Coronary Angiography, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Atrial Fibrillation, medicine, Humans, Prospective Studies, Myocardial infarction, Stroke, MINOCA, biology, business.industry, Hazard ratio, Atrial fibrillation, General Medicine, Prognosis, medicine.disease, Coronary Vessels, Troponin, Confidence interval, Coronary arteries, medicine.anatomical_structure, biology.protein, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Mace
Abstract

Background: A definition of myocardial infarction with non-obstructive coronary arteries (MINOCA) was published by European Society of Cardiology in 2016. The aim of this study is to analyze the clinical profile and prognosis of these patients in a prospective single-center study and compare it with the literature data. Methods: During a 3-year period, information from every consecutive MINOCA patient was gathered (n = 109). It was then compared with 412 contemporaneous patients with myocardial infarction and obstructive coronary arteries (MIOCA). Univariate and multivariate analyses were performed. Prognosis analysis was adjusted by age and cardiovascular risk factors (CVRF). Results: MINOCA represented 16.9% of the total of patients admitted for myocardial infarction. Compared with MIOCA, they had more psychosocial disorders (22.9% vs. 10.7%; p < 0.01) and more pro-inflammatory conditions (34.9% vs. 14.0%; p < 0.01). Atrial fibrillation was twice as frequent in MINOCA (14.7% vs. 7.3%; p = 0.016). Predictors of MINOCA were as follows: female gender, absence of diabetes, absence of tobacco use, tachycardia, troponin above 10 times the 99 th percentile, and pro-inflammatory conditions. Median follow-up was 17.3 ± 9.3 months. Major adverse cardiovascular events (MACE; a composite of a recurrence of acute myocardial infarction, transient ischemic attack/stroke, or death from cardiovascular cause and death from any cause) occurred in 10.8% of the MINOCA group as compared with 10.7% in the MIOCA group (hazard ratio [HR] 1.19, 95% confidence interval [CI] 0.58–2.45; p = 0.645). Cardiovascular re-admission rates were higher in the MINOCA group: 19.8% vs. 13.9% (HR 1.85; CI 1.06–3.21; p = 0.030). Conclusions: The frequency of MINOCA is high, with fewer CVRF, and it is linked to atrial fibrillation, psychosocial disorders, and pro-inflammatory conditions. Mid-term prognosis is worse than previously thought, with a similar proportion of MACE as compared to MIOCA, and even a higher rate of cardiovascular re-admissions.

Published
2022
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18. Tromboembolismo pulmonar agudo: adecuación del manejo de pacientes según las guías de práctica clínica en el servicio de urgencias

Author

María del Carmen Pérez-García, Regina Gálvez-López, Antonio Jesús Láinez-Ramos-Bossini, Mario Rivera-Izquierdo, S. Moreno-Suárez, and F. Garrido Sanz

Subjects
Gynecology, 03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, business.industry, medicine, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, 030204 cardiovascular system & hematology, business, medicine.disease, Pulmonary embolism
Abstract

Resumen Antecedentes y objetivo Evaluar la frecuencia de tromboembolismo pulmonar agudo (TEPA), el uso de escalas de probabilidad clinica (EPC) y la adecuacion del manejo de los pacientes a los que se solicito angiografia pulmonar por tomografia computarizada (angio-TC) por sospecha de TEPA desde el servicio de urgencias. Materiales y metodos Estudio observacional retrospectivo de las angio-TC solicitadas desde el servicio de urgencias para descartar TEPA. Se analizaron variables clinicas y el uso explicito de EPC. Se determino la adecuacion del manejo en funcion de las escalas de Wells (EW) y Ginebra (EG) y sus versiones simplificadas (EWs y EGs), calculadas retrospectivamente. Resultados Se incluyeron 534 pacientes (52,8% mujeres, mediana de edad: 73 anos). La frecuencia de TEPA fue del 23,0% y el uso explicito de la EW, del 15,2%. La adecuacion del manejo fue variable dependiendo de la EPC (54,5-75,8%) y del dimero D estandar o ajustado por edad. Conclusiones La baja utilizacion explicita de la EW no conlleva un manejo inadecuado, y el juicio clinico global puede ofrecer un rendimiento similar a las EPC, pero es necesario realizar estudios especificos para comprobar esta hipotesis.

Published
2022
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19. Multi-criteria risk classification to enhance complex supply networks performance

Author

Silvia Carpitella, Joaquín Izquierdo, Ilyas Mzougui, Carpitella S., Mzougui I., and Izquierdo J.

Subjects
Supply chain risk management, Application Article, Computer science, business.industry, Automotive industry, Management Science and Operations Research, Multiple-criteria decision analysis, Computer Science Applications, Management Information Systems, Intervention (law), Identification (information), Risk analysis (engineering), Multi-criteria decision-making, ELECTRE TRI, ELECTRE, MATEMATICA APLICADA, Set (psychology), business, Supply chain management, Risk management, Information Systems, Supply chain risk
Abstract

[EN] Management of complex supply networks is a fundamental business topic today. Especially in the presence of many and diverse stakeholders, identifying and assessing those risks having a potential negative impact on the performance of supply processes is of utmost importance and, as a result, implementing focused risk management actions is a current lively field of research. The possibility of supporting Supply Chain Risks Management (SCRM) is herein explored from a Multi-Criteria Decision-Making (MCDM)-based perspective. The sorting method ELimination Et Choix Traduisant la REalite (ELECTRE) TRI is proposed as a structural procedure to classify Supply Chain Risks (SCRs) into proper risk classes expressing priority of intervention so as to ease the implementation of prevention and protection measures. This approach is intended to offer structured management insights by means of an immediate identification of the most highly critical risks in a wide set of previously identified SCRs. A real-world case study in the field of the automotive industry is implemented to show the applicability and usefulness of the approach.

Published
2021

20. Severity and duration of allergic conjunctivitis: are they associated with severity and duration of allergic rhinitis and asthma?

Author

Javier Montoro, V Matheu, Ignacio Dávila, A Navarro, A del Cuvillo, Carmen Rondon, Paloma Campo, M Velasco, M L González, Francisco Vega, M T Dordal, Ruperto González-Pérez, Adriana Izquierdo-Domínguez, M C Sánchez-Hernández, A Valero, Carlos Colás, A Puiggros, B Fernández-Parra, A Fernández-Palacín, M Lluch-Bernal, [Sánchez-Hernández MC, Navarro AM] Allergology UGS, Hospital Universitario Virgen Macarena, Sevilla, Spain. [Dordal MT] Allergy Unit, Department of Internal Medicine, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain. [Dávila I] Allergy Service, Hospital Universitario de Salamanca, Salamanca, Spain.[Fernández-Parra B] Department of Allergology, Hospital El Bierzo, Ponferrada, León, Spain. [Colás C] Department of Allergology, Hospital Clínico Universitario, Zaragoza, Spain. [Izquierdo-Domínguez A] Servei d'Al·lergologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Clínica Diagonal, Barcelona, Spain, and Consorci Sanitari de Terrassa

Subjects
Adult, medicine.medical_specialty, Adolescent, Population, Respiratory Tract Diseases::Nose Diseases::Rhinitis [DISEASES], Dermatitis, Atopic, Young Adult, Food allergy, Internal medicine, enfermedades respiratorias::enfermedades nasales::rinitis [ENFERMEDADES], Epidemiology, medicine, Humans, Immunology and Allergy, Child, education, Rinitis, Asma, Aged, Conjunctivitis, Allergic, Rhinitis, Asthma, Aged, 80 and over, education.field_of_study, Eye Diseases::Conjunctival Diseases::Conjunctivitis [DISEASES], business.industry, allergic respiratory disease, Respiratory disease, Infant, Atopic dermatitis, Respiratory Tract Diseases::Bronchial Diseases::Asthma [DISEASES], Middle Aged, medicine.disease, Rhinitis, Allergic, Allergic conjunctivitis, allergic conjunctivitis, Allergic comorbidity, one airway, Child, Preschool, Etiology, oftalmopatías::enfermedades de la conjuntiva::conjuntivitis [ENFERMEDADES], enfermedades respiratorias::enfermedades bronquiales::asma [ENFERMEDADES], epidemiology, Conjuntivitis, business
Abstract

Comorbiditat al·lèrgica; Conjuntivitis al·lèrgica; Malaltia respiratòria al·lèrgica Allergic comorbidity; Allergic conjunctivitis; Allergic respiratory disease Comorbilidad alérgica; Conjuntivitis alérgica; Enfermedad respiratoria alérgica Objective. The association of allergic conjunctivitis (AC) with rhinitis and/or asthma is poorly understood. The objective of this study was to apply the Consensus Document for Allergic Conjunctivitis (DECA) criteria for the classification of AC to a population of patients with AC to assess the association between the severity and duration of AC and rhinitis and/or asthma. Methods. Patients with ocular symptoms of AC who participated in the 'Alergológica 2015' study were included. The demographics, classification according to the DECA criteria, etiology, and comorbidities were evaluated by age groups (less or equal than 14 and greater than 14 years). Results. A total of 2,914 patients (age range, 1-90 years) were included in the "Alergológica 2015" study. Of these, 965 patients (33.1%) were diagnosed with AC (77.5% > 14 years). AC was classified as severe, moderate, or mild in 1.8%, 46.4%, and 51.8%, respectively; and as intermittent or persistent in 51.6% and 48.4% of the patients. AC alone occurred in 4% of patients. AC was mainly associated with rhinitis (88.4%), asthma (38.2%), food allergy (8.3%) and atopic dermatitis (3.5%). In allergic respiratory disease rhinitis preceded AC and asthma developed later. The severity and duration of AC was significantly associated with severity and duration of rhinitis (p less than 0.001 for both age groups) and asthma (p less than 0.001 only in adults). Conclusions. The application of the new DECA classification for AC reveals a direct relationship between AC, rhinitis and asthma respect to severity and duration. These relationships suggest that AC should be considered an integral part of the "one airway, one disease" hypothesis.

Published
2022

21. TIPS FOR THRIVING IN AN ECOMMERCE MARKETPLACE: Flexibility, collaboration and automation offer keys to success in an omnichannel world

Author

Izquierdo, Jorge

Subjects
Electronic commerce -- Marketing, Electronic commerce, Company marketing practices, Business, Containers and packaging industries
Abstract

Let's face it: The ecommerce revolution has not only changed the rules for consumer packaged goods (CPG) companies, it has created a whole new game in which COVID-19 has only [...]

Published
2020

22. Detecting Serial Arcs in Aeronautical Applications Using Inductive Sensors

Author

Gabriel Barroso de Maria, Daniel Izquierdo, Guillermo Robles, Manuel Gomez de la Calle, and Juan Manuel Martínez-Tarifa

Subjects
business.industry, Computer science, Electrical engineering, Aerospace Engineering, Line (electrical engineering), DC-BUS, Electric arc, Fuselage, Electrical and Electronic Engineering, Inductive sensor, business, Electronic circuit, Voltage, DC bias
Abstract

There is a clear trend in the aircraft industry to use more electrical systems in propulsion and electromechanical and electrohydraulic actuators to comply with environmental sustainability and to improve reliability and maintenance processes. The increase of electrical consumption requires an increase of the rated voltages to supply power to these so called More Electrical Aircraft (MEA). Unfortunately, this voltage rise, currently up to 540 Vdc, can lead to ionization processes within the electric wiring due to the lower air density at high altitudes. As a consequence, a degraded insulation can create extremely hazardous events in flight such as arcs between wires (serial) or between wires and fuselage (parallel). Serial arcs in DC bus circuits are specially dangerous for the aircraft operation, so its detection within fractions of seconds is required to ensure a reliable operation. However, during a sustained serial arc the rated current can be passing through air deceiving the protections and avoiding their tripping. In this work, it has been found that arcing introduces high frequency current pulses superimposed to the DC component that can be identified to detect the occurrence of an arc. The frequency components of these pulses depend on the line characteristics and can be detected with inductive sensors. This manuscript also designs and tests a light and inexpensive sensor for arc detection in aircraft applications.

Published
2022
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23. Invasive pneumococcal disease in children under 60 months before and after availability of 13-valent conjugate vaccine

Author

Luis Salleras, Sergi Hernández, Sonia Uriona, Juan José García-García, Mariona Fernández de Sevilla, Carmen Muñoz-Almagro, Gemma Codina, Magda Campins, Cristina Esteva, Alvaro Díaz, Angela Domínguez, Pilar Ciruela, Anna Solé-Ribalta, Fernando A. Moraga-Llop, Sebastià González-Peris, Johanna Martínez-Osorio, Conchita Izquierdo, and Ana María Planes

Subjects
Serotype, Pediatrics, medicine.medical_specialty, medicine.medical_treatment, Population, Serogroup, medicine.disease_cause, Pneumococcal Infections, Pneumococcal conjugate vaccine, Pneumococcal Vaccines, Conjugate vaccine, Management of Technology and Innovation, Streptococcus pneumoniae, medicine, Humans, Prospective Studies, Child, education, Mechanical ventilation, education.field_of_study, Vaccines, Conjugate, business.industry, Incidence (epidemiology), bacterial infections and mycoses, medicine.disease, Pneumonia, Child, Preschool, business, medicine.drug
Abstract

BACKGROUND Invasive pneumococcal disease (IPD) is the most important bacterial infection in young children, and the introduction of pneumococcal conjugate vaccines has changed its presentation. This study compared the incidence, characteristics and serotype distribution of IPD before and after the introduction of the pneumococcal conjugate vaccine (PCV13). METHODS Prospective enrolment of patients with IPD aged less than 60 months and admitted to either of 2 tertiary care hospitals between January 2007 and December 2009 (pre-PCV13 period) and January 2012 and June-2016 (PCV13 period). RESULTS We identified 493 cases, 319 in the pre-PCV13 period and 174 in the PCV13 period. The incidence of IPD decreased from 89.7 to 34.4 casos per 100 000 habitantes ( -62%; P

Published
2022
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24. Factores asociados al estrés prenatal y la ansiedad en gestantes durante el COVID-19 en España

Author

María Teresa Izquierdo-Puchol, Natalia Awad-Sirhan, Juanita Cajiao-Nieto, Yerko Molina-Muñoz, and Sandra Simó-Teufel

Subjects
business.industry, Protective factor, General Medicine, Computer-assisted web interviewing, Mental health, Snowball sampling, Prenatal stress, Health care, medicine, Anxiety, Observational study, medicine.symptom, business, General Nursing, Clinical psychology
Abstract

AIM OF THE STUDY To describe prenatal stress and state anxiety levels in pregnant women living in Spain during the lockdown of the first wave of COVID-19 and its relation with obstetric factors, perception of health care, and concerns about the socio-sanitary situation. METHODS The present study is an observational, correlational, and cross-sectional quantitative study. The participants in the study were pregnant women recruited through non-probabilistic convenience and snowball sampling during the lockdown. A web link was provided to an online questionnaire designed for this research, which collected socio-demographic and obstetric variables, perceptions of health care received during the pandemic and preoccupations associated with COVID-19. It also included the Prenatal Stress Questionnaire (PDQ) and the State Anxiety Inventory (STAI-S). RESULTS Based on the responses of 695 pregnant women, the results showed a mean of 16.98 (SD=25.20) of prenatal stress and elevated levels of anxiety (M=25.20/ SD=11.07) in the first wave of the pandemic. Risk factors for prenatal stress and anxiety were the level of preoccupation associated with COVID-19 and previous mental health issues. A specific risk factor for anxiety was having more than one child and a protective factor were perceiving accessibility and availability of health care, with clear and consistent pregnancy care and follow-up protocols. CONCLUSIONS The lockdown period for COVID-19 was a stressful experience for pregnant women, highlighting the need to address their psychological well-being through clear and coherent protocols in terms of maternal-foetal health control and follow-up.

Published
2022
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26. Role of Botulinum Toxin in Pectoralis Minor Syndrome

Author

Paolo Tripodi, Dorelly Tanayra Martinez Del Carmen, Francisco Xavier Martí Mestres, Ricard Ramos Izquierdo, Ivan Macia Vidueia, and Antonio Romera Villegas

Subjects
Adult, medicine.medical_specialty, Botulinum Toxins, Decompression, Pectoralis Muscles, Young Adult, medicine, Spastic, Humans, Thoracic outlet syndrome, Rib cage, Cervical rib, business.industry, Cervical Rib, General Medicine, Middle Aged, Decompression, Surgical, medicine.disease, Neurovascular bundle, Botulinum toxin, Surgery, Thoracic Outlet Syndrome, Treatment Outcome, Pectoralis Minor, Cardiology and Cardiovascular Medicine, business, medicine.drug
Abstract

Introduction : Thoracic outlet syndrome (TOS) causes neurogenic symptoms in 95% of the cases due to neurovascular bundle compression. The treatment goal is the decompression of the neurovascular structures. In the last decade, non-surgical treatments have been evaluated as a treatment option for spastic syndromes and thoracic outlet syndrome. In this study we report the use of botulinum toxin (BTX-A) injection as a diagnostic tool to identify the pectoral minor syndrome, and as a less aggressive treatment-option. Methods : An observational cohort study of patients with neurogenic thoracic outlet syndrome who underwent sonographically guided chemodenervation of pectoral minor muscle with botulinum toxin. Follow-up includes clinical evaluation at one month, 3 months and 6 months after the procedure. Clinical evaluation was made with clinical questionnaire. In case of patients with partial improvement of the symptoms, a second infiltration of BTX-A was performed. The categorical variables were shown as percentages, and the continuous variables as mean and standard deviation (SD). For the comparison of categorical variables, the Fisher's exact test was used. Statistical analysis was performed using the SPSS version 20.0 program. We consider p Results : A total of twenty-six patients were diagnosed with thoracic outlet syndrome in this period, and 20 accomplished the inclusion criteria. Seven patients were excluded (1 due to neoplasia, 2 did not sign the informed consent, 1 due to neoplasia, 2 did not sign the informed consent, 1 was lost during the follow-up and 3 due to anomalies of the first rib secondary to fractures and cervical rib and 1 was lost during the follow-up), therefore a sample of 13 patients aged between 24 and 55 years was obtained. The most common type of procedure performed was the single injection of 50 IU of botulinum toxin. Four patients were infiltrated in two occasions due to partial improvement in symptoms at one-month follow-up. Clinical stability was found at three months and at six months follow-up. Conclusion : The ultrasound-guided botulinum injection of the pectoralis minor muscles provides symptoms relief in patients with pectoral minor syndrome, and could be considered a safe tool in the diagnosis of the pectoralis minor syndrome within the spectrum of thoracic operculum syndrome.

Published
2022
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27. ANTES: Un año después en la EPOC

Author

Julio Ancochea, Juan Luis García Rivero, Ciro Casanova, Cruz González, Jose Echave-Sustaeta, Juan José Soler Cataluña, Borja G. Cosío, Bernardino Alcázar, J Alberto Fernandez Villar, Alvar Agusti, Felipe Villar-Álvarez, Germán Peces-Barba, Miguel Roman, Bartolome R. Celli, Jesús Molina, José Luis López-Campos, José Luis Izquierdo, Javier Martín Sánchez, Marc Miravitlles, and José María Marín Trigo

Subjects
Pulmonary and Respiratory Medicine, business.industry, Medicine, business, Humanities
Published
2022
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28. Evaluación agronómica y fisiológica en clones de camote (Ipomoea batatas) sometidos a condiciones de estrés hídrico

Author

Gustavo Adolfo Rodríguez-Izquierdo, Edwin Andres Villagran-Munar, Mercedes Pérez-Macias, Rommel Igor León-Pacheco, Francia Concepción Fuenmayor-Campos, and Adrián José Rodríguez-Izquierdo

Subjects
Irrigation, productivity, Vegetative reproduction, growth, crecimiento, Drought tolerance, Soil Science, Biomass, gas exchange, drought, sequía, Ipomoea, Crop, Transpiration, productividad, biology, business.industry, intercambio gaseoso, Agriculture, biology.organism_classification, Horticulture, business, Agronomy and Crop Science, Food Science
Abstract

Resumen Introducción. Las raíces y tubérculos como el camote (Ipomoea batatas L.) se encuentran entre los seis primeros cultivos más importantes del mundo. Sin embargo, esta especie es sensible al estrés por déficit hídrico. El uso de genotipos resistentes a la sequía y mejores prácticas de gestión del agua pueden mejorar la calidad y el rendimiento de la raíz. Para ampliar la productividad en tales ambientes se pueden utilizar prácticas de riego complementario o identificar genotipos con potencial de rendimiento promisorios frente a estas condiciones. Objetivo. Evaluar el efecto del estrés hídrico en variables fisiológicas y agronómicas en clones de camote. Materiales y métodos. Se realizó un ensayo en el período de abril-julio 2015 en el Centro Nacional de Investigación Agropecuaria, Maracay, Venezuela, con tres repeticiones bajo un diseño en parcelas divididas, donde la parcela principal estuvo conformada por tres niveles de riego (todo el ciclo, dos y tres primeros meses con riego) y la parcela secundaria por tres clones de camote. Se midieron variables asociadas al intercambio gaseoso, crecimiento vegetativo, biomasa y rendimiento. Resultados. Las plantas de camote frente a condiciones de sequía disminuyeron su crecimiento, expansión foliar, cerraron en forma parcial los estomas para evitar pérdidas de agua por transpiración sin afectar las variables de tasa neta de asimilación de CO2, rendimiento y acumulación de biomasa. El mejor clon fue el 64, con mayor transpiración, acumulación de biomasa y rendimiento de 18,3 t ha-1. El riego en todo el cultivo generó el mayor crecimiento vegetativo con 125 hojas planta-1. Conclusiones. Bajo condiciones de estrés hídrico las plantas de camote se adaptaron fisiológicamente para no perder agua por la transpiración sin sacrificar las tasas de fotosíntesis, con las cuales los clones lograron alcanzar una acumulación de biomasa aérea, raíces y rendimiento del tubérculo similar al cultivo con riego. Abstract Introduction. Roots and tubers, such as sweet potatoes (Ipomoea batatas L.), are among the top six most important crops worldwide. However, this species is sensitive to stress due to water deficit. The use of drought resistant genotypes and better water management practices can enhance its’ root quality and yield. In order to enhance productivity in those environments, complementary irrigation practices can be used or genotypes with promising yield potential against these conditions can be identified. Objective. To evaluate the effect of water stress on physiological and agronomic variables in sweet potato clones. Materials and methods. A trial was conducted from April to July 2015 at the National Center for Agricultural Research, Maracay, Venezuela, with three replications under a split plot design, where the principal plot was integrated by three irrigation treatments (all cycles, two, and three first months with irrigation) and the secondary plot by three sweet potatoes clones. Variables associated with gas exchange, vegetative growth, biomass, and yield were measured. Results. The results show that sweet potato plants against drought conditions decreased their growth, foliar expansion, partially closed the stomata avoiding water losses through transpiration without affecting the variables of net assimilation rate of CO2, yield, and biomass accumulation. The best clone with increased transpiration, biomass accumulation, and yield of 18.3 t ha-1 was the 64. Irrigation throughout the crop cycle generated the highest vegetative growth with 125 leaves plant-1. Conclusions. Under water stress conditions, sweet potato plants adapted physiologically to avoid water loss through transpiration without sacrificing photosynthetic rates, with which the clones were able to accumulate aerial biomass, roots, and tuber yield similar to the irrigated crop.

Published
2021
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29. Eficacia de los aparatos de expansión rápida maxilar Hyrax y Haas

Author

Maria Cristina Rockenbach Binz, Karla Kamila Vallejo Izquierdo, Luis Alberto Vallejo Izquierdo, David Eduardo Vallejo Izquierdo, and Jenny Edith Collantes Acuña

Subjects
Orthodontics, medicine.medical_specialty, Hyrax, biology, business.industry, Orthopedic surgery, medicine, Rapid maxillary expansion, biology.organism_classification, business
Abstract

Este estudio evalua la eficacia que tienen los disyuntores dento-muco-soportados Haas y dento-soportados Hyrax, en tratamientos para corregir deficiencias del arco transversal superior, siguiendo los protocolos de activación tuvieron efectos ortopédicos satisfactorios durante la expansión maxilar rápida. Los resultados no tuvieron mayor relevancia entre estos, sin embargo, se recomienda Hyrax por la asepsia para el paciente.

Published
2021
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30. A global experiment on motivating social distancing during the COVID-19 pandemic

Author

Legate, N, Ngyuen, T-V, Weinstein, N, Moller, A, Legault, L, Vally, Z, Tajchman, Z, Zsido, AN, Zrimsek, M, Chen, Z, Ziano, I, Gialitaki, Z, Ceary, CD, Jang, Y, Lin, Y, Kunisato, Y, Yamada, Y, Xiao, Q, Jiang, X, Du, X, Yao, E, Ryan, WS, Wilson, JP, Cyrus-Lai, W, Jimenez-Leal, W, Law, W, Unanue, W, Collins, WM, Richard, KL, Vranka, M, Ankushev, V, Schei, V, DePaola, C, Lerche, V, Kovic, V, Križanić, V, Kadreva, VH, Adoric, VC, Tran, US, Yeung, SK, Hassan, W, Houston, R, Machin, MA, Lima, TJS, Ostermann, T, Frizzo, T, Sverdrup, TE, House, T, Gill, T, Fedotov, M, Paltrow, T, Jernsäther, T, Rahman, T, Machin, T, Koptjevskaja-Tamm, M, Hostler, TJ, Ishii, T, Szaszi, B, Adamus, S, Suter, L, von Bormann, SM, Habib, S, Studzinska, A, Stojanovska, D, Janssen, SMJ, Stieger, S, Schulenberg, SE, Tatachari, S, Azouaghe, S, Sorokowski, P, Sorokowska, A, Song, X, Morbée, S, Lewis, S, Sinkolova, S, Grigoryev, D, Drexler, SM, Daches, S, Levine, SL, Geniole, SN, Akter, S, Vračar, S, Massoni, S, Costa, S, Zorjan, S, Sarioguz, E, Izquierdo, SM, Tshonda, SS, Alves, SG, Pöntinen, S, Solas, SÁ, Ordoñez-Riaño, S, Očovaj, SB, Onie, S, Lins, S, Biberauer, T, Çoksan, S, Khumkom, S, Sacakli, A, Ruiz-Fernández, S, Geiger, SJ, FatahModares, S, Walczak, RB, Betlehem, R, Vilar, R, Cárcamo, RA, Ross, RM, McCarthy, R, Ballantyne, T, Westgate, EC, Ryan, RM, Gargurevich, R, Afhami, R, Ren, D, Monteiro, RP, Reips, U-D, Reggev, N, Calin-Jageman, RJ, Pourafshari, R, Oliveira, R, Nedelcheva-Datsova, M, Rahal, R-M, Ribeiro, RR, Radtke, T, Searston, R, Jai-ai, R, Habte, R, Zdybek, P, Chen, S-C, Wajanatinapart, P, Maturan, PLG, Perillo, JT, Isager, PM, Kačmár, P, Macapagal, PM, Maniaci, MR, Szwed, P, Hanel, PHP, Forbes, PAG, Arriaga, P, Paris, B, Parashar, N, Papachristopoulos, K, Correa, PS, Kácha, O, Bernardo, M, Campos, O, Bravo, ON, Galindo-Caballero, OJ, Ogbonnaya, CE, Bialobrzeska, O, Kiselnikova, N, Simonovic, N, Cohen, N, Nock, NL, Hernandez, A, Thogersen-Ntoumani, C, Ntoumanis, N, Johannes, N, Albayrak-Aydemir, N, Say, N, Neubauer, AB, Martin, NI, Levy, N, Torunsky, N, Antwerpen, NV, Doren, NV, Sunami, N, Rachev, NR, Majeed, NM, Schmidt, N-D, Nadif, K, Corral-Frías, NS, Ouherrou, N, Abbas, N, Pantazi, M, Lucas, MY, Vasilev, MR, Victoria Ortiz, M, Butt, MM, Kurfalı, M, Kabir, M, Muda, R, Rivera, MDCMCT, Sirota, M, Seehuus, M, Parzuchowski, M, Toro, M, Hricova, M, Maldonado, MA, Rentzelas, P, Vansteenkiste, M, Metz, MA, Marszalek, M, Karekla, M, Mioni, G, Bosma, MJ, Westerlund, M, Vdovic, M, Bialek, M, Silan, MA, Anne, M, Misiak, M, Gugliandolo, MC, Grinberg, M, Capizzi, M, Espinoza Barría, MF, Kurfali, MA, Mensink, MC, Harutyunyan, M, Khosla, M, Dunn, MR, Korbmacher, M, Adamkovič, M, Ribeiro, MFF, Terskova, M, Hruška, M, Martončik, M, Jansen, M, Voracek, M, Čadek, M, Frias-Armenta, M, Kowal, M, Topor, M, Roczniewska, M, Oosterlinck, M, Kohlová, MB, Paruzel-Czachura, M, Sabristov, M, Romanova, M, Papadatou-Pastou, M, Lund, ML, Antoniadi, M, Magrin, ME, Jones, MV, Li, M, Ortiz, MS, Manavalan, M, Muminov, A, Kossowska, M, Friedemann, M, Wielgus, M, van Hooff, MLM, Varella, MAC, Standage, M, Nicolotti, M, Colloff, MF, Bradford, M, Vaughn, LA, Eudave, L, Vieira, L, Lu, JG, Pineda, LMS, Matos, L, Pérez, LC, Lazarevic, LB, Jaremka, LM, Smit, ES, Kushnir, E, Ferguson, LJ, Anton-Boicuk, L, Lins de Holanda Coelho, G, Ahlgren, L, Liga, F, Levitan, CA, Micheli, L, Gunton, L-A, Volz, L, Stojanovska, M, Boucher, L, Samojlenko, L, Delgado, LGJ, Kaliska, L, Beatrix, L, Warmelink, L, Rojas-Berscia, LM, Yu, K, Wylie, K, Wachowicz, J, Desai, K, Barzykowski, K, Kozma, L, Evans, K, Kirgizova, K, Emmanuel Agesin, BB, Koehn, MA, Wolfe, K, Korobova, T, Morris, K, Klevjer, K, van Schie, K, Vezirian, K, Damnjanović, K, Thommesen, KK, Schmidt, K, Filip, K, Staniaszek, K, Grzech, K, Hoyer, K, Moon, K, Khaobunmasiri, S, Rana, K, Janjić, K, Suchow, JW, Kielińska, J, Cruz Vásquez, JE, Chanal, J, Beitner, J, Vargas-Nieto, JC, Roxas, JCT, Taber, J, Urriago-Rayo, J, Pavlacic, JM, Benka, J, Bavolar, J, Soto, JA, Olofsson, JK, Vilsmeier, JK, Messerschmidt, J, Czamanski-Cohen, J, Waterschoot, J, Moss, JD, Boudesseul, J, Lee, JM, Kamburidis, J, Joy-Gaba, JA, Zickfeld, J, Miranda, JF, Verharen, JPH, Hristova, E, Beshears, JE, Djordjevic, JM, Bosch, J, Valentova, JV, Antfolk, J, Berkessel, JB, Schrötter, J, Urban, J, Röer, JP, Norton, JO, Silva, JR, Pickering, JS, Vintr, J, Uttley, J, Kunst, JR, Ndukaihe, ILG, Iyer, A, Vilares, I, Ivanov, A, Ropovik, I, Sula, I, Sarieva, I, Metin-Orta, I, Prusova, I, Pinto, I, Bozdoc, AI, Almeida, IAT, Pit, IL, Dalgar, I, Zakharov, I, Arinze, AI, Ihaya, K, Stephen, ID, Gjoneska, B, Brohmer, H, Flowe, H, Godbersen, H, Kocalar, HE, Hedgebeth, MV, Chuan-Peng, H, Sharifian, M, Manley, H, Akkas, H, Hajdu, N, Azab, H, Kaminski, G, Nilsonne, G, Anjum, G, Travaglino, GA, Feldman, G, Pfuhl, G, Czarnek, G, Marcu, GM, Hofer, G, Banik, G, Adetula, GA, Bijlstra, G, Verbruggen, F, Kung, FYH, Martela, F, Foroni, F, Forest, J, Singer, G, Muchembled, F, Azevedo, F, Mosannenzadeh, F, Marinova, E, Štrukelj, E, Etebari, Z, Bradshaw, EL, Baskin, E, Garcia, EOL, Musser, E, van Steenkiste, IMM, Ahn, ER, Quested, E, Pronizius, E, Jackson, EA, Manunta, E, Agadullina, E, Šakan, D, Dursun, P, Dujols, O, Dubrov, D, Willis, M, Tümer, M, Beaudry, JL, Popović, D, Dunleavy, D, Djamai, I, Krupić, D, Herrera, D, Vega, D, Du, H, Mola, D, Chakarova, D, Davis, WE, Holford, DL, Lewis, DMG, Vaidis, DC, Ozery, DH, Ricaurte, DZ, Storage, D, Sousa, D, Alvarez, DS, Boller, D, Rosa, AD, Dimova, D, Marko, D, Moreau, D, Reeck, C, Correia, RC, Whitt, CM, Lamm, C, Solorzano, CS, von Bastian, CC, Sutherland, CAM, Overkott, C, Aberson, CL, Wang, C, Niemiec, CP, Karashiali, C, Noone, C, Chiu, F, Picciocchi, C, Brownlow, C, Karaarslan, C, Cellini, N, Esteban-Serna, C, Reyna, C, Ferreyra, C, Batres, C, Li, R, Grano, C, Carpentier, J, Tamnes, CK, Fu, CHY, Ishkhanyan, B, Bylinina, L, Jaeger, B, Bundt, C, Allred, TB, Vermote, BJ, Bokkour, A, Bogatyreva, N, Shi, J, Chopik, WJ, Antazo, B, Behzadnia, B, Becker, M, Bayyat, MM, Cocco, B, Chou, W-L, Barkoukis, V, Hubena, B, Žuro, B, Aczel, B, Baklanova, E, Bai, H, Balci, BB, Babinčák, P, Soenens, B, Dixson, BJW, Mokady, A, Kappes, HB, Atari, M, Szala, A, Szabelska, A, Aruta, JJB, Domurat, A, Arinze, NC, Modena, A, Adiguzel, A, Monajem, A, ARABI, KAITEL, Özdoğru, AA, Rothbaum, AO, Torres, AO, Theodoropoulou, A, Skowronek, A, Jurković, AP, Singh, A, Kassianos, AP, Findor, A, Hartanto, A, Landry, AT, Ferreira, A, Santos, AC, De la Rosa-Gomez, A, Gourdon-Kanhukamwe, A, Luxon, AM, Todsen, AL, Karababa, A, Janak, A, Pilato, A, Bran, A, Tullett, AM, Kuzminska, AO, Krafnick, AJ, Urooj, A, Khaoudi, A, Ahmed, A, Groyecka-Bernard, A, Askelund, AD, Adetula, A, Belaus, A, Charyate, AC, Wichman, AL, Stoyanova, A, Greenburgh, A, Thomas, AG, Arvanitis, A, Forscher, PS, Mallik, PR, Coles, NA, Miller, JK, Moshontz, H, Urry, HL, IJzerman, H, Basnight-Brown, DM, Ebersole, CR, Chartier, CR, Buchanan, EM, Primbs, MA, Department of Psychology, Education and Child Studies, Clinical Psychology, Legate, N, Nguyen, T, Weinstein, N, Moller, A, Legault, L, Vally, Z, Tajchman, Z, Zsido, A, Zrimsek, M, Chen, Z, Ziano, I, Gialitaki, Z, Ceary, C, Jang, Y, Lin, Y, Kunisato, Y, Yamada, Y, Xiao, Q, Jiang, X, Du, X, Yao, E, Ryan, W, Wilson, J, Cyrus-Lai, W, Jimenez-Leal, W, Law, W, Unanue, W, Collins, W, Richard, K, Vranka, M, Ankushev, V, Schei, V, Lerche, V, Kovic, V, Krizanic, V, Kadreva, V, Adoric, V, Tran, U, Yeung, S, Hassan, W, Houston, R, Machin, M, Lima, T, Ostermann, T, Frizzo, T, Sverdrup, T, House, T, Gill, T, Fedotov, M, Paltrow, T, Jernsather, T, Rahman, T, Machin, T, Koptjevskaja-Tamm, M, Hostler, T, Ishii, T, Szaszi, B, Adamus, S, Suter, L, von Bormann, S, Habib, S, Studzinska, A, Stojanovska, D, Janssen, S, Stieger, S, Schulenberg, S, Tatachari, S, Azouaghe, S, Sorokowski, P, Sorokowska, A, Song, X, Morbee, S, Lewis, S, Sinkolova, S, Grigoryev, D, Drexler, S, Daches, S, Levine, S, Geniole, S, Akter, S, Vracar, S, Massoni, S, Costa, S, Zorjan, S, Sarioguz, E, Izquierdo, S, Tshonda, S, Alves, S, Pontinen, S, Solas, S, Ordonez-Riano, S, Ocovaj, S, Onie, S, Lins, S, Biberauer, T, Coksan, S, Khumkom, S, Sacakli, A, Ruiz-Fernandez, S, Geiger, S, Modares, S, Walczak, R, Betlehem, R, Vilar, R, Carcamo, R, Ross, R, Mccarthy, R, Ballantyne, T, Westgate, E, Ryan, R, Gargurevich, R, Afhami, R, Ren, D, Monteiro, R, Reips, U, Reggev, N, Calin-Jagema, R, Pourafshari, R, Oliveira, R, Nedelcheva-Datsova, M, Rahal, R, Ribeiro, R, Radtke, T, Searston, R, Jai-ai, R, Habte, R, Zdybek, P, Chen, S, Wajanatinapart, P, Maturan, P, Perillo, J, Isager, P, Kacmar, P, Macapagal, P, Maniaci, M, Szwed, P, Hanel, P, Forbes, P, Arriaga, P, Paris, B, Parashar, N, Papachristopoulos, K, Correa, P, Kacha, O, Bernardo, M, Campos, O, Bravo, O, Galindo-Caballero, O, Ogbonnaya, C, Bialobrzeska, O, Kiselnikova, N, Simonovic, N, Cohen, N, Nock, N, Hernandez, A, Thogersen-Ntouma, C, Ntoumanis, N, Johannes, N, Albayrak-Aydemir, N, Say, 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C., De La Rosa-Gomez, A., Gourdon-Kanhukamwe, A., Luxon, A. M., Todsen, A. L., Karababa, A., Janak, A., Pilato, A., Bran, A., Tullett, A. M., Kuzminska, A. O., Krafnick, A. J., Department of Industrial Engineering and Management, Aalto-yliopisto, Aalto University, Massey, D., Kurfali, Merve A., Collaboration, Psychological Science Accelerator Self-Determination Theory, FdR overig onderzoek, Persuasive Communication (ASCoR, FMG), and Organizational Psychology

Subjects
behavior change, Coronavirus disease 2019 (COVID-19), 230 Affective Neuroscience, INTENTIONS, L400, self-determination theory, Physical Distancing, Social Sciences, Intention, Ciências Sociais::Psicologia [Domínio/Área Científica], FATIGUE, motivation, PARENTAL PROHIBITION, SDG 3 - Good Health and Well-being, Pandemic, Humans, health communication, MESSAGES, Sociology, Pandemics, METAANALYSIS, COVID-19, Behaviour Change and Well-being, Multidisciplinary, business.industry, Social distance, Public relations, Motivation, INTERNALIZATION, business, BEHAVIOR
Abstract

Significance\ud \ud Communicating in ways that motivate engagement in social distancing remains a critical global public health priority during the COVID-19 pandemic. This study tested motivational qualities of messages about social distancing (those that promoted choice and agency vs. those that were forceful and shaming) in 25,718 people in 89 countries. The autonomy-supportive message decreased feelings of defying social distancing recommendations relative to the controlling message, and the controlling message increased controlled motivation, a less effective form of motivation, relative to no message. Message type did not impact intentions to socially distance, but people’s existing motivations were related to intentions. Findings were generalizable across a geographically diverse sample and may inform public health communication strategies in this and future global health emergencies.\ud \ud \ud \ud Abstract\ud \ud Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This cross-country, preregistered experiment (n = 25,718 from 89 countries) tested hypotheses concerning generalizable positive and negative outcomes of social distancing messages that promoted personal agency and reflective choices (i.e., an autonomy-supportive message) or were restrictive and shaming (i.e., a controlling message) compared with no message at all. Results partially supported experimental hypotheses in that the controlling message increased controlled motivation (a poorly internalized form of motivation relying on shame, guilt, and fear of social consequences) relative to no message. On the other hand, the autonomy-supportive message lowered feelings of defiance compared with the controlling message, but the controlling message did not differ from receiving no message at all. Unexpectedly, messages did not influence autonomous motivation (a highly internalized form of motivation relying on one’s core values) or behavioral intentions. Results supported hypothesized associations between people’s existing autonomous and controlled motivations and self-reported behavioral intentions to engage in social distancing. Controlled motivation was associated with more defiance and less long-term behavioral intention to engage in social distancing, whereas autonomous motivation was associated with less defiance and more short- and long-term intentions to social distance. Overall, this work highlights the potential harm of using shaming and pressuring language in public health communication, with implications for the current and future global health challenges.

Published
2022
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31. Factors associated with readmission to the Emergency Department in a cohort of COVID-19 hospitalized patients

Author

Antonio Cárdenas-Cruz, Pablo Redruello-Guerrero, Antonio Jesús Láinez-Ramos-Bossini, Mario Rivera-Izquierdo, Álvaro Romero-Duarte, [Romero-Duarte, Alvaro] Univ Granada, Fac Med, Granada 18016, Spain, [Redruello-Guerrero, Pablo] Univ Granada, Fac Med, Granada 18016, Spain, [Rivera-Izquierdo, Mario] Hosp Univ Clin San Cecilio, Serv Prevent Med & Publ Hlth, Granada 18016, Spain, [Rivera-Izquierdo, Mario] Univ Granada, Dept Prevent Med & Publ Hlth, Granada 18016, Spain, [Rivera-Izquierdo, Mario] Inst Biosanitario Granada Ibs GRANADA, Granada 37007, Spain, [Jesus Lainez-Ramos-Bossini, Antonio] Virgen de las Nieves Univ Hosp, Dept Radiol, Granada 18016, Spain, [Jesus Lainez-Ramos-Bossini, Antonio] Univ Granada, PhD Programme Clin Med & Publ Hlth, Granada 18016, Spain, [Cardenas-Cruz, Antonio] Univ Granada, Dept Med, Granada 18016, Spain, [Cardenas-Cruz, Antonio] Hosp Poniente, Intens Care Unit, Almeria 04003, Spain, 'Artificial Intelligence for the diagnosis and prognosis of COVID-19' project - Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades, Junta de Andalucia, and FEDER funds

Subjects
medicine.medical_specialty, Longitudinal study, Coronavirus disease 2019 (COVID-19), business.industry, Medical record, COVID-19, Emergency department, Logistic regression, medicine.disease_cause, Coronavirus, Hospitalization, Internal medicine, Superinfection, Cohort, Symptoms, Emergency, medicine, Observational study, business, Post-discharge
Abstract

This work was supported by the 'Artificial Intelligence for the diagnosis and prognosis of COVID-19' project (CV20-29480), funded by the Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades, Junta de Andalucia, and the FEDER funds. We acknowledge the Faculty of Medicine, University of Granada, for the successful organization of the final degree projects, since this work was designed and conducted during the project of Alvaro Romero-Duarte. We also acknowledge all the healthcare workers from the Department of Preventive Medicine and Public Health, San Cecilio University Hospital for their restless commitment during the pandemic of COVID-19 and their continuous efforts for investigating and communicating their results to the scientific community. Finally, we thank the SEMERGEN-UGR Chair of Teaching and Research in Family Medicine for being an example of support and encouragement in Primary Care research., Introduction: The aim of this study was to describe the symptomatology and main factors associated with readmission to the Emergency Department (ED) in COVID-19 patients discharged from hospital during the first wave of the pandemic at the San Cecilio University Hospital, Granada, Spain. Methods: An observational longitudinal study was conducted in a cohort of 441 patients admitted to our hospital with confirmed SARS-CoV-2 polymerase chain reaction (PCR) from 1 March to 15 April 2020. Patients were followed up through medical records 6 months after discharge. Sociodemographic, clinical and symptomatologic variables were collected. Descriptive, bivariate and multivariate logistic regression analyses were performed. Results: The mean age of patients in the cohort was 66.4 years (s = 15.3), with 55.1% men. In-hospital mortality was 18.1%. The presence of persistent symptomatology was high (64.5%), especially respiratory (53.2%), systemic (46.3%) and neurological (31.0%). A total of 75 (20.8%) patients were readmitted to the ED during the 6 months following hospital discharge. The main factors associated with readmission to the ED were polymedication (P = 0.031), living in a care home (P = 0.014), fever (P = 0.047), general malaise (P < 0.001), thoracic pain (P < 0.001), headache (P = 0.012), hematological symptoms (P = 0.011), nephrological symptoms (P = 0.047), depressive symptoms (P = 0.009), syncope or hypotension (P = 0.006) and superinfection (P = 0.018). After multivariate adjustment analysis, thoracic pain (OR: 4.45, 95% CI: 1.88– 10.52), general malaise and hematological symptoms (OR: 3.95, 95% CI: 1.12–13.89) remained as risk factors. Conclusions: The presence of persistent symptomatology after hospital discharge in our cohort was common and varied. Polymedication and living in a care home made up the most vulnerable profile of COVID-19 patients for returning to the ED. Thoracic pain, general malaise and hematological symptoms were identified as potential markers of severity, along with others predictors. These findings might be useful for optimizing follow-up strategies. Future studies conducted in other geographical areas are necessary to corroborate our results., 'Artificial Intelligence for the diagnosis and prognosis of COVID-19' project - Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades CV20-29480, Junta de Andalucia European Commission

Published
2022

32. Sisal fiber reinforced hollow concrete blocks for structural applications: Testing and modeling

Author

Izquierdo, Indara Soto, Izquierdo, Orieta Soto, Ramalho, Marcio Antonio, and Taliercio, Alberto

Subjects
Hemp (Fiber) -- Research, Concrete cracking -- Analysis, Hollow concrete blocks -- Research -- Mechanical properties, Business, Construction and materials industries
Abstract

ABSTRACT An experimental programme was carried out to investigate the mechanical behavior of masonry elements made of concrete and natural sisal fibers. Compression tests were carried out on individual hollow [...]

Published
2017
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33. Antibody formation against SARS-CoV-2 in imatinib-treated COVID-19 patients

Author

Juan Víctor San Martín-López, Nieves Mesa-Plaza, L Molina-Esteban, María Toledano-Macías, Aida Izquierdo-Martínez, Jaime García de Tena, Alejandro Morales-Ortega, Ana Isabel Farfán-Sedano, Guillermo Soria Fernández-Llamazares, David Bernal-Bello, Sonia Gonzalo-Pascua, Cristina Llarena-Barroso, Santiago Prieto-Menchero, and Beatriz Jaenes-Barrios

Subjects
Microbiology (medical), 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Antibodies, Viral, Article, delayed second vaccine dose, RBD-binding IgG antibody, Humans, Medicine, BNT162b2 vaccine, SARS-CoV-2, business.industry, SARS-CoV-2 infection, COVID-19, neutralizing antibody, Imatinib, antibody response, Virology, adverse events, mRNA vaccine, Infectious Diseases, Antibody Formation, Imatinib Mesylate, business, Antibody formation, medicine.drug
Published
2022
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34. High-Linearity Tunable Low-Gₘ Transconductor Based on Bootstrapping

Author

C.A. De La Cruz-Blas, O. J. Cinco-Izquierdo, M. T. Sanz-Pascual, Universidad Pública de Navarra. Departamento de Ingeniería Eléctrica, Electrónica y de Comunicación, and Nafarroako Unibertsitate Publikoa. Ingeniaritza Elektriko, Elektroniko eta Telekomunikazio Saila

Subjects
Physics, Total harmonic distortion, business.industry, Amplifier, Transconductance, Resistance, Resistors, Electrical engineering, Buffer amplifier, Linearity, Analog CMOS, Current mirrors, Transistors, law.invention, Bootstrapping (electronics), law, Bootstrapping, Power demand, Electrical and Electronic Engineering, Resistor, Low Gm OTA, business, Voltage
Abstract

In this brief, a novel pseudo-differential low-transconductance amplifier is proposed based on the bootstrapping technique. The transconductor is implemented using two voltage follower topologies as amplifiers with their outputs connected to both terminals of a resistor, thus bootstrapping the voltages at these terminals to increase the equivalent resistance value, and achieve a very low transconductance without the need for large passive components. In this way, a highly-linear compact structure is designed whose transconductance can be tuned by external current sources. The circuit was fabricated in a standard 0.18μm CMOS process. The experimental results show a tunable transconductance in the range of tens of nA/V, with a total harmonic distortion lower than -40dB at 350mVpp@1kHz. The power consumption of the amplifier is 4μW under a 1.8V supply voltage. This work was supported by CONACYT through the Doctoral Grant 467255 and the Research Project CONACYT CB-2015-257985

Published
2022
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35. Spike-based COVID-19 immunization increases antibodies to nucleocapsid antigen

Author

Alberto L. García-Basteiro, Josep Vidal-Alaball, Gemma Moncunill, Ruth Aguilar, Anna Ramirez-Morros, Anna Ruiz-Comellas, Rocío Rubio, Marta Vidal, Luis Izquierdo, Alfons Jiménez, Carlota Dobaño, and Selena Alonso

Subjects
COVID-19 Vaccines, Coronavirus disease 2019 (COVID-19), nucleocapsid, Antibodies, Viral, Article, Antigen, Pfizer, avidity, vaccine, antibody, Physiology (medical), Humans, Medicine, breakthrough, Multiplex, Avidity, Longitudinal Studies, biology, SARS-CoV-2, business.industry, Immunogenicity, Biochemistry (medical), Public Health, Environmental and Occupational Health, COVID-19, spike, General Medicine, Virology, Immunoglobulin A, Vaccination, Immunization, Moderna, Immunoglobulin G, Spike Glycoprotein, Coronavirus, biology.protein, Antibody, business
Abstract

Antibodies to the nucleocapsid (N) antigen are suggested to be used to monitor infections after COVID-19 vaccination, as first generation subunit vaccines are based on the spike (S) protein. We used multiplex immunoassays to simultaneously measure antibody responses to different fragments of the SARS-CoV-2 S and N antigens for evaluating the immunogenicity of the mRNA-1273 (Spykevax) and the BNT162b2 (Comirnaty) vaccines in 445 health care workers. We report a >4-fold increase post-vaccination of IgG levels to the full length (N FL) and C-terminus of N (N CT) in 5.2% and 18.0% of individuals, respectively, and of IgA in 3.6% (N FL) and 9.0% (N CT) of them. The increase in IgG levels and avidity was more pronounced after Spykevax than Comirnaty vaccination (36.2% vs 13.1% for N CT, and 10.6% vs 3.7% for N FL). Data suggest the induction of cross-reactive antibodies against the N CT region after administering these S-based vaccines, and this should be taken into account when using N seropositivity to detect breakthroughs.

Published
2022
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36. Defining the Heterogeneity of Sleep Apnea Syndrome: A Cluster Analysis With Implications for Patient Management

Author

Jesús Fernández Francés, Sofía Romero-Peralta, Olga Mediano, Jorge Castelao, Rodrigo Sabroso, Francisco García-Río, Esther Viejo-Ayuso, José Luis Izquierdo, and Pilar Resano Barrio

Subjects
Pulmonary and Respiratory Medicine, Pediatrics, medicine.medical_specialty, business.industry, Apnea, Sleep apnea, Disease, medicine.disease, Comorbidity, Obstructive sleep apnea, Mood, Cohort, medicine, Sleep study, medicine.symptom, business
Abstract

Introduction Obstructive sleep apnea (OSA) is a complex pathology with heterogeneity that has not been fully characterized to date. Our objective is to identify groups of patients with common clinical characteristics through cluster analysis that could predict patient prognosis, the impact of comorbidities and/or the response to a common treatment. Methods Cluster analysis was performed using the hierarchical cluster method in 2025 patients in the apnea-HUGU cohort. The variables used for building the clusters included general data, comorbidity, sleep symptoms, anthropometric data, physical exam and sleep study results. Results Four clusters were identified: (1) young male without comorbidity with moderate apnea and otorhinolaryngological malformations; (2) middle-aged male with very severe OSA with comorbidity without cardiovascular disease; (3) female with mood disorder; and (4) symptomatic male with established cardiovascular disease and severe OSA. Conclusions The characterization of these four clusters in OSA can be decisive when identifying groups of patients who share a special risk or common therapeutic strategies, orienting us toward personalized medicine and facilitating the design of future clinical trials.

Published
2022
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37. Integrating Provenance Capture and UML With UML2PROV: Principles and Experience

Author

Saenz-Adan, Carlos, Perez, Beatriz, Garcia-Izquierdo, Francisco J., Moreau, Luc, 0000-0003-2485-3182, 0000-0001-9235-7311, 0000-0003-0972-0787, and 0000-0002-3494-120X

Subjects
Provenance, Unified Modeling Language, Computer science, business.industry, Software engineering, business, computer, Software, computer.programming_language
Abstract

In response to the increasing calls for algorithmic accountability, UML2PROV is a novel approach to address the existing gap between application design, where models are described by UML diagrams, and provenance design, where generated provenance is meant to describe an application’s flows of data, processes and responsibility, enabling greater accountability of this application. The originality of UML2PROV is that designers are allowed to follow their preferred software engineering methodology to create the UML Diagrams for their application, while UML2PROV takes the UML diagrams as a starting point to automatically generate: (1) the design of the provenance to be generated (expressed as PROV templates); and (2) the software library for collecting runtime values of interest (encoded as variable-value associations known as bindings), which can be deployed in the application without developer intervention. At runtime, the PROV templates combined with the bindings are used to generate high-quality provenance suitable for subsequent consumption. UML2PROV is rigorously defined by an extensive set of 17 patterns mapping UML diagrams to provenance templates, and is accompanied by a reference implementation based on Model Driven Development techniques. A systematic evaluation of UML2PROV uses quantitative data and qualitative arguments to show the benefits and trade-offs of applying UML2PROV for software engineers seeking to make applications provenance-aware. In particular, as the UML design drives both the design and capture of provenance, we discuss how the levels of detail in UML designs affect aspects such as provenance design generation, application instrumentation, provenance capability maintenance, storage and run-time overhead, and quality of the generated provenance. Some key lessons are learned such as: starting from a non-tailored UML design leads to the capture of more provenance than required to satisfy provenance requirements and therefore, increases the overhead unnecessarily; alternatively, if the UML design is tailored to focus on addressing provenance requirements, only relevant provenance gets to be collected, resulting in lower overheads.

Published
2022
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38. Diversidad económica regional y desempeño socioeconómico en las provincias del Ecuador (período 2014-2018)

Author

Paola Alexandra Carangui Velecela and Wilson Santiago Izquierdo Rodríguez

Subjects
HB1-3840, HF5001-6182, Economic theory. Demography, concentración económica, desarrollo económico, desarrollo regional, estructura económica, geografía económica, Business
Abstract

El presente artículo tiene como objetivo estimar el efecto de la diversidad económica regional sobre las condiciones socioeconómicas en las provincias del Ecuador, tomando como referencia el período 2014-2018. La investigación es de tipo explicativa, con diseño documental, no experimental, transversal y emplea como métodos de análisis los enfoques analítico-sintético y cuantitativo-empírico. Las estimaciones econométricas efectuadas con datos de corte transversal de las 24 provincias del Ecuador, con el método de Mínimos Cuadrados Ordinarios, sugieren efectos positivos del coeficiente de especialización regional y del índice de concentración sobre la volatilidad observada en el ingreso y en el crecimiento. Así mismo, la especialización regional se asocia con una mayor tasa de pobreza, mientras que hay una relación inversa entre especialización y concentración con la tasa promedio de crecimiento de las provincias. El estudio permitió concluir, en primer lugar, que la planificación del desarrollo exige la reducción de las heterogeneidades productivas que presenta una economía como Ecuador y, en segundo lugar, que los beneficios del desarrollo sólo serán ampliamente percibidos por la población en la medida que las regiones diversifican su actividad económica.

Published
2022
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39. Predicting Cardiorespiratory Fitness in Female Soccer Players: The Basque Female Football Cohort Study

Author

Julen Castellano, Eduardo Lusa Cadore, Mikel Izquierdo, Ibai Garcia-Tabar, Aitor Iturricastillo, and Igor Setuain

Subjects
Male, medicine.medical_specialty, Football, Physical Therapy, Sports Therapy and Rehabilitation, Cohort Studies, Oxygen Consumption, Heart Rate, Operational equations, Internal medicine, Soccer, Linear regression, Heart rate, Blood lactate, Humans, Medicine, Orthopedics and Sports Medicine, Lactic Acid, business.industry, Cardiorespiratory fitness, Physiological responses, Cardiorespiratory Fitness, Spain, Exercise Test, Cardiology, Female, business, Anaerobic exercise, Cohort study
Abstract

Purpose: To develop gender-specific operational equations for prediction of cardiorespiratory fitness in female footballers. Method: Forty-eight semiprofessional female footballers performed an intermittent progressive maximal running test for determination of fixed blood lactate concentration (FBLC) thresholds. Relationships between FBLC thresholds and the physiological responses to submaximal running were examined. Developed equations (n = 48) were compared with equations previously obtained in another investigation performed in males (n = 100). Results: Submaximal velocity associated with 90% maximal heart rate was related to FBLC thresholds (r = .76 to .79; P R2 = .82 to .94) of a single blood lactate concentration (BLC) sample measured at 10 or 11.5 km·h−1 was very high. A single BLC sample taken after a 5-minute running bout at 8.5 km·h−1 was related to FBLC thresholds (r = −.71; P P = .15) in the regression lines predicting FBLC thresholds from velocity associated with 90% maximal heart rate was observed between the female and male cohorts. However, regressions estimating FBLC thresholds by a single BLC sample were different (P = .002). Conclusions: Velocity associated with 90% maximal heart rate was robustly related to FBLC thresholds and might serve for mass field testing independently of sex. BLC equations accurately predicted FBLC thresholds. However, these equations are gender-specific. This is the first study reporting operational equations to estimate the FBLC thresholds in female footballers. The use of these equations reduces the burden associated with cardiorespiratory testing. Further cross-validation studies are warranted to validate the proposed equations and establish them for mass field testing.

Published
2022
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40. Compact and Wideband Crossed Dipole Antenna Using Coupling Stub for Circular Polarization

Author

Wei Hu, Steven Gao, Lehu Wen, Chao Wang, Benito Sanz-Izquierdo, Jian Wu, and Xiaofei Ren

Subjects
Physics, Coupling, business.industry, Bandwidth (signal processing), Input impedance, Stub (electronics), law.invention, Optics, law, Dipole antenna, Electrical and Electronic Engineering, Antenna (radio), Antenna gain, Wideband, business
Abstract

A novel compact and wideband circularly polarized (CP) crossed dipole antenna is presented. To realize CP radiation, a new design concept of using coupling stub is first illustrated. The coupling stub is equivalent as a combination of a dipole-c and dipole-y. The dipole-c not only couples proper energy from the x-axis arranged driven dipole-x to the orthogonally arranged dipole-y, but also provides quadrature phase delay to the dipole-y. Therefore, CP radiation is realized for the presented configuration. To improve the input impedance caused by the strong coupling, a long narrow strip is incorporated for the enhancement of impedance bandwidth. Based on the design concept, a compact and wideband CP antenna by using the coupling stub and stepped square loop is developed to further increase the operation bandwidth and realize stable radiation. The designed antenna was finally fabricated for performance verification. Both the simulation and measurement show that the developed antenna can have a wide overlapped impedance and AR bandwidth from 1.1 to 1.74 GHz with a compact radiator size. In addition, stable antenna gain and radiation patterns are achieved for wireless communications.

Published
2022
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41. Ontology verification testing using lexico-syntactic patterns

Author

Alba Fernández-Izquierdo and Raúl García-Castro

Subjects
Information Systems and Management, Computer science, business.industry, Process (engineering), Software requirements specification, Repetitive task, Ontology (information science), Computer Science Applications, Theoretical Computer Science, Domain (software engineering), Artificial Intelligence, Control and Systems Engineering, Lexico, Software engineering, business, computer, Software, Software verification, computer.programming_language
Abstract

Ontology verification refers to the activity where an ontology is tested against its ontology requirements to ensure that it is built correctly in compliance with its ontology requirements specification. Therefore, it is an important activity that should be performed in any ontology development process. Since manual verification can be a time-consuming and repetitive task, testing processes to automatically verify an ontology facilitate this activity. Moreover, the involvement of not only ontology engineers during the ontology verification process , but also domain experts and users, can provide valuable feedback to avoid misunderstandings and lack of information. This paper proposes a method for ontology verification that defines the testing activities to be performed. The method uses a testing language based on lexico-syntactic patterns to facilitate the definition of tests and an ontology to store and publish such tests. Moreover, this verification testing method proposes an online tool to execute tests on one or more ontologies. The method was compared in terms of time and errors by user evaluation with other tools for ontology verification; the evaluation showed that the tools that use testing languages had better results in terms of reducing errors in the verification activity compared to the tools that do not.

Published
2022
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42. Tomographic behavior of pneumonia caused by SARS-CoV-2

Author

Eva A. Izquierdo-Echávarri, Francisco J. Ayala-Ochoa, Luis A. Concha-Rebollar, Luis F. Alva-López, and Vito S. Hernández-Melchor

Subjects
Adult, Male, medicine.medical_specialty, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Ground-glass opacity, Young Adult, medicine, Medical imaging, Humans, Chest tomography, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Respiratory disease, Transverse axis, COVID-19, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Pneumonia, Female, Radiology, medicine.symptom, Tomography, X-Ray Computed, business
Abstract

From the first report of the respiratory disease caused by SARS-Cov-2 towards the end of 2019, in Wuhan, China, to June 8, 2020, 6,931,000 people had been affected in the world, and 113,619 in Mexico, where there is a lack of literature describing the tomographic behavior of this disease throughout its evolution and its correlation with patient clinical data.To identify, describe and classify the manifestations detected on chest computed tomography images of patients with pneumonia caused by SARS-CoV-2.Hospitalized patients with RT-PCR-confirmed SARS-CoV-2 infection and who underwent a plain chest tomography were included.The most common tomographic patterns were ground glass opacity, consolidation, cobblestone pattern and mixed pattern, with peripheral and subpleural distribution and bilateral involvement in up to 95 %. Subpleural bands that distorted the architecture were identified in up to 62 % of patients, with an average of seven days of evolution. The most common extrapulmonary finding was an increase in pulmonary artery transverse axis.Knowing the behavior of this type of pneumonia allows becoming familiarized with the characteristic tomographic patterns, in order to aid timely detection and treatment.Desde el primer reporte de la enfermedad respiratoria causada por SARS-Cov-2 a finales de 2019, en Wuhan, China, hasta el 8 de junio de 2020, habían sido afectadas 6 931 000 personas en el mundo y 113 619 en México, donde se carece de informes que describan el comportamiento tomográfico de esta enfermedad a lo largo de su evolución y su correlación con los datos clínicos del paciente.Identificar, describir y clasificar las manifestaciones en las imágenes de tomografía de tórax de pacientes con neumonía causada por SARS-CoV-2.Se incluyeron pacientes hospitalizados con infección por SARS-CoV-2 confirmada mediante PCR-TR y en quienes se realizó tomografía simple de tórax.Los patrones tomográficos más comunes fueron opacidad de vidrio despulido, consolidación, empedrado y patrón mixto, con distribución periférica, subpleural y afectación bilateral hasta en 95 %. Se identificaron bandas subpleurales que distorsionaban la arquitectura hasta en 62 % de los pacientes, con un promedio de siete días de evolución. El aumento del eje transverso de la arteria pulmonar constituyó el hallazgo extrapulmonar más frecuente.Conocer el comportamiento de este tipo de neumonía permite la familiarización con los patrones tomográficos característicos, con el fin de coadyuvar a la detección y tratamiento oportunos.

Published
2023
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43. Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE)

Author

Nicola Disma, Katalin Virag, Thomas Riva, Jost Kaufmann, Thomas Engelhardt, Walid Habre, Christian Breschan, Rudolf Likar, Manuela Platzer, Isole Edelman, Johanes Eger, Stefan Heschl, Brigitte Messerer, Maria Vittinghof, Ruth Kroess, Martina Stichlberger, David Kahn, Thierry Pirotte, Caroline Pregardien, Francis Veyckemans, France Stevens, Johan Berghmans, Annemie Bauters, Luc De Baerdemaeker, Stefan De Hert, Koen Lapage, Aliaksandra Parashchanka, Jurgen Van Limmen, Piet Wyffels, Julie Lauweryns, Nadia Najafi, Joris Vundelinckx, Diana Butković, Ivana Kerovec Sorić, Sandra Kralik, Ana Markić, Josip Azman, Josko Markic, Daniela Pupacic, Michal Frelich, Petr Reimer, René Urbanec, Petra Cajková, Vladimír Mixa, Yvona Sedláčková, Lenka Knoppová, Alena Zlámalová (neé Květoňová), Martin Vavřina, Jiří Žurek, Tom Hansen, Arash Afshari, Anders Bastholm Bille, Marguerite Ellekvist, Mari-Liis Ilmoja, Reet Moor, Reet Kikas, Merle Väli, Kariantti Kallio, Elisa Reponen, Pertti Suominen, Sami Suvanto, Raisa Vähätalo, Hannu Kokki, Merja Kokki, Jarkko Harju, Miia Kokkonen, Jenni Vieri, Tuula Manner, Catherine Amory, Hugues Ludot, Dina Bert, Juliette Godart, Anne Laffargue, Hervé Dupont, Benjamin Urbina, Catherine Baujard, Philippe Roulleau, Giuseppe Staiti, Maryline Bordes, Karine Nouette Gaulain, Yann Hamonic, François Semjen, Olivier Jacqmarcq, Caroline Lejus-Bourdeau, Cécile Magne, Léa Petry, Lilica Ros, Aurélien Zang, Mehdi Bennis, Bernard Coustets, Rose Fesseau, Isabelle Constant, Eliane Khalil, Nada Sabourdin, Noemie Audren, Thomas Descarpentries, Fanny Fabre, Aurélien Legrand, Emilie Druot, Gilles Orliaguet, Lucie Sabau, Lynn Uhrig, François de la Brière, Karin Jonckheer, Jean-Paul Mission, Lucia Scordo, Caroline Couchepin, Christophe Dadure, Pablo De la Arena, Laurent Hertz, Philippe Pirat, Chrystelle Sola, Myriam Bellon, Souhayl Dahmani, Florence Julien-Marsollier, Daphne Michelet, Veronique Depret-Donatien, Anne Lesage, Michael Laschat, Frank Wappler, Karin Becke, Lena Brunner, Karin Oppenrieder, Gregor Badelt, Karin Hochmuth, Bernhard Koller, Anita Reil, Sebastian Richter, Thomas Fischer, Anja Diers, Clemens Schorer, Andreas Weyland, Ruth Cohausz, Franz-Josef Kretz, Michaela Löffler, Markus Wilbs, Claudia Hoehne, Johanna Ulrici, Christiane Goeters, Armin Flinspach, Matthias Klages, Simone Lindau, Leila Messroghli, Kai Zacharowski, Christoph Eisner, Thomas Mueller, Daniel Richter, Melanie Schäfer, Markus Weigand, Sebastian Weiterer, Miriam Ochsenreiter, Michael Schöler, Tom Terboven, Isabel Eggemann, Sascha Haussmann, Nicolas Leister, Christoph Menzel, Uwe Trieschmann, Sirin Yücetepe, Susanna Keilig, Peter Kranke, Yvonne Jelting, Torsten Baehner, Richard Ellerkmann, Shahab Ghamari, Claudia Neumann, Martin Söhle, Pelagia Chloropoulou, Vagia Ntritsou, Pinelopi Papagiannopoulou, Eleana Garini, Afroditi Karafotia, Panagoula Mammi, Evangelia Bali, Despoina Iordanidou, Anna Malisiova, Artemis Polyzoi, Adelais Tsiotou, Erzsebet Sapi, Edgar Székely, Nandor Kosik, Veronika Maráczi, Janos Schnur, Judit Csillag, János Gál, Gergely Göbl, Balázs Hauser, András Petróczy, Gyula Tövisházi, Stuart Blain, Sarah Gallagher, Sinead Harte, Mandy Jackson, Emma Meehan, Zeenat Nawoor, Brendan O’Hare, Mark Ross, Daniela Lerro, Marinella Astuto, Chiara Grasso, Rita Scalisi, Giulia Frasacco, Elena Lenares, Roberto Leone, Maurizia Grazzini, Carmelo Minardi, Nicola Zadra, Gilda Cinnella, Antonella Cotoia, Dario Galante, Brita De Lorenzo, Beate Kuppers, Giulia Bottazzi, Fabio Caramelli, Maria Cristina Mondardini, Emanuele Rossetti, Sergio Picardo, Alessandro Vittori, Anna Camporesi, Andrea Wolfler, Edoardo Calderini, Laura Brigitta Colantonio, Simona Anna Finamore, Giuliana Anna Porro, Rachele Bonfiglio, Svetlana Kotzeva, Leila Mameli, Girolamo Mattioli, Camilla Micalizzi, Alessia Montaguti, Angela Pistorio, Clelia Zanaboni, Anna Guddo, Gerald Rogan Neba, Moreno Favarato, Bruno Guido Locatelli, Micol Maffioletti, Valter Sonzogni, Rossella Garra, Maria Sammartino, Fabio Sbaraglia, Andrea Cortegiani, Alessandra Moscarelli, Elena Attanasi, Simonetta Tesoro, Cristina Agapiti, Francesca Pinzoni, Cesare Vezzoli, Federico Bilotta, Arta Barzdina, Zane Straume, Anda Zundane, Laura Lukosiene, Irena Maraulaite, Ilona Razlevice, Bernd Schmitz, Stephanie Mifsud, Carolin Aehling, Celia Allison, Rients De Boer, Dina Emal, Markus Stevens, Marielle Buitenhuis, Jurgen de Graaff, Inge De Liefde, Andreas Machotta, Gail Scoones, Lonneke Staals, Jeremy Tomas, Anouk Van der Knijff-van Dortmont, Marianne Veldhuizen, David Alders, Wolfgang Buhre, Eva Schafrat, Jan Schreiber, Petronella Mari Vermeulen, Mark Hendriks, Sandra Lako, Marieke Voet-Lindner, Barbe Pieters, Gert-Jan Scheffer, Luc Tielens, Anthony R. Absalom, Margot Bergsma, Joke De Ruiter, Sascha Meier, Martin Volkers, Tjerk Zweers, Anne M. Beukers, Christa Boer, Jurgen Dertinger, Sandra Numan, Bas Van Zaane, Wenche B. Boerke, Nil Ekiz, Kristoffer Stensrud, Inger Marie Drage, Erik Ramon Isern, Alicja Bartkowska-Sniatkowska, Malgorzata Grzeskowiak, Magdalena Juzwa-Sobieraj, Jowita Rosada-Kurasińska, Artur Baranowski, Karina Jakubowska, Dorota Lewandowska, Magdalena Mierzewska-Schmidt, Piotr Sawicki, Magdalena Urban-Lechowicz, Pomianek Przemyslaw, Marzena Zielinska, Teresa Leal, Maria Soares, Pedro Pina, Sílvia Pinho, Maria Domingas Patuleia, Catarina Cruz Esteves, Helena Salgado, Maria João Santos, Rodica Badeti, Iulia Cindea, Loredana Oana, Adriana Gurita, Luminita Ilie, Gabriel Mocioiu, Radu Tabacaru, Irina Trante, Valentin Munteanu, Mihai Morariu, Emese Nyíri, Ivana Budic, Vesna Marjanovic, Biljana Drašković, Marina Pandurov, Jordanka Ilic, Ana Mandras, Zdenka Rados, Nikola Stankovic, Maja Suica, Sladjana Vasiljevic, Mirjana Knezevic, Irina Milojevic, Ivana Petrov, Selena Puric Racic, Dusica Simic, Irena Simic, Marija Stevic, Irena Vulicevic, Barbora Cabanová, Miloslav Hanula, Jelena Berger, Darja Janjatovic, Špela Pirtovšek Štupnik, Dolores Méndez, Gema Pino, Paloma Rubio, Alberto Izquierdo, Silvia López, Cristina González Serrano, Jesús Cebrián, Ana Peleteiro, Pilar Del Rey de Diego, Ernesto Martínez García, Carolina Tormo de las Heras, Pablo Troncoso Montero, Celia Arbona, David Artés, Alicia Chamizo, Silvia Serrano, Montserrat Suarez Comas, Francisco Escribá, Cristina Auli, Osvaldo Pérez Pardo, Natalia Sierra Biddle, Ceferina Suárez Castaño, María Isabel Villalobos Rico, Susana Manrique Muñoz, Irene García Martínez, Nuria Montferrer Estruch, Elena Vilardell Ortíz, Rodrigo Poves-Álvarez, Ivan Kohn, Ulf Lindestam, Jarl Reinhard, Albert Castellheim, Kerstin Sandström, Sporre Bengt, Rainer Dörenberg, Peter Frykholm, Maria Garcia, Ann Kvarnström, Emma Pontén, Thomas Bruelisauer, Gabor Erdoes, Heiko Kaiser, Mathias Marchon, Stefan Seiler, Yann Bögli, Mirko Dolci, Carine Marcucci, Isabelle Pichon, Laszlo Vutskits, Mattias Casutt, Martin Hölzle, Thomas Hurni, Martin Jöhr, Anna-Ursina Malär, Jacqueline Mauch, Thomas Erb, Karin Oeinck, Mine Akin, Gulsen Keskin, Yesim Senayli, Guner Kaya, Pinar Kendigelen, Ayse Çiğdem Tutuncu, Zehra Hatipoğlu, Dilek Özcengiz, Hale Aksu Erdost, Elvan Öçmen, Çimen Olguner, Hilmi Ayanoglu, Pelin Corman Dincer, Tumay Umuroglu, Mustafa Azizoglu, Handan Birbiçer, Nurcan Doruk, Aslı Sagun, Sibel Baris, Dmytro Dmytriiev, Sridevi Kuchi, Nuria Masip, Peter Brooks, Alison Hare, Nargis Ahmad, Michelle Casey, Sam De Silva, Nadine Dobby, Prakash Krishnan, L. Amaki Sogbodjor, Ellie Walker, Suellen Walker, Stephanie King, Katy Nicholson, Michelle Quinney, Paul Stevens, Andrew Blevin, Mariangela Giombini, Chulananda Goonasekera, Sadia Adil, Stephanie Bew, Carol Bodlani, Dan Gilpin, Stephanie Jinks, Nalini Malarkkan, Alice Miskovic, Rebecca Pad, Juliet Wolfe Barry, Joy Abbott, James Armstrong, Natalie Cooper, Lindsay Crate, John Emery, Kathryn James, Hannah King, Paul Martin, Stefano Scalia Catenacci, Rob Bomont, Paul Smith, Sara Mele, Alessandra Verzelloni, Philippa Dix, Graham Bell, Elena Gordeva, Lesley McKee, Esther Ngan, Jutta Scheffczik, Li-En Tan, Mark Worrall, Carmel Cassar, Kevin Goddard, Victoria Barlow, Vimmi Oshan, Khairi Shah, Sarah Bell, Lisa Daniels, Monica Gandhi, David Pachter, Chris Perry, Andrew Robertson, Carmen Scott, Lynne Waring, David Barnes, Sophie Childs, Joanne Norman, Robin Sunderland, Dowell Julia, Feijten Prisca, Harlet Pierre, Herbineaux Sarah, Leva Brigitte, Plichon Benoît, Virág Katalin, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Anesthesiology, HUS Children and Adolescents, Children's Hospital, Clinicum, Anestesiologian yksikkö, Disma, Nicola, Virag, Katalin, Riva, Thoma, Kaufmann, Jost, Engelhardt, Thoma, Habre, Walid, Breschan, Christian, Likar, Rudolf, Platzer, Manuela, Edelman, Isole, Eger, Johane, Heschl, Stefan, Messerer, Brigitte, Vittinghof, Maria, Kroess, Ruth, Stichlberger, Martina, Kahn, David, Pirotte, Thierry, Pregardien, Caroline, Veyckemans, Franci, Stevens, France, Berghmans, Johan, Bauters, Annemie, De Baerdemaeker, Luc, De Hert, Stefan, Lapage, Koen, Parashchanka, Aliaksandra, Van Limmen, Jurgen, Wyffels, Piet, Lauweryns, Julie, Najafi, Nadia, Vundelinckx, Jori, Butković, Diana, Kerovec Sorić, Ivana, Kralik, Sandra, Markić, Ana, Azman, Josip, Markic, Josko, Pupacic, Daniela, Frelich, Michal, Reimer, Petr, Urbanec, René, Cajková, Petra, Mixa, Vladimír, Sedláčková, Yvona, Knoppová, Lenka, Zlámalová (neé Květoňová), Alena, Vavřina, Martin, Žurek, Jiří, Hansen, Tom, Afshari, Arash, Bille, Anders Bastholm, Ellekvist, Marguerite, Ilmoja, Mari-Lii, Moor, Reet, Kikas, Reet, Väli, Merle, Kallio, Kariantti, Reponen, Elisa, Suominen, Pertti, Suvanto, Sami, Vähätalo, Raisa, Kokki, Hannu, Kokki, Merja, Harju, Jarkko, Kokkonen, Miia, Vieri, Jenni, Manner, Tuula, Amory, Catherine, Ludot, Hugue, Bert, Dina, Godart, Juliette, Laffargue, Anne, Dupont, Hervé, Urbina, Benjamin, Baujard, Catherine, Roulleau, Philippe, Staiti, Giuseppe, Bordes, Maryline, Nouette Gaulain, Karine, Hamonic, Yann, Semjen, Françoi, Jacqmarcq, Olivier, Lejus-Bourdeau, Caroline, Magne, Cécile, Petry, Léa, Ros, Lilica, Zang, Aurélien, Bennis, Mehdi, Coustets, Bernard, Fesseau, Rose, Constant, Isabelle, Khalil, Eliane, Sabourdin, Nada, Audren, Noemie, Descarpentries, Thoma, Fabre, Fanny, Legrand, Aurélien, Druot, Emilie, Orliaguet, Gille, Sabau, Lucie, Uhrig, Lynn, de la Brière, Françoi, Jonckheer, Karin, Mission, Jean-Paul, Scordo, Lucia, Couchepin, Caroline, Dadure, Christophe, De la Arena, Pablo, Hertz, Laurent, Pirat, Philippe, Sola, Chrystelle, Bellon, Myriam, Dahmani, Souhayl, Julien-Marsollier, Florence, Michelet, Daphne, Depret-Donatien, Veronique, Lesage, Anne, Laschat, Michael, Wappler, Frank, Becke, Karin, Brunner, Lena, Oppenrieder, Karin, Badelt, Gregor, Hochmuth, Karin, Koller, Bernhard, Reil, Anita, Richter, Sebastian, Fischer, Thoma, Diers, Anja, Schorer, Clemen, Weyland, Andrea, Cohausz, Ruth, Kretz, Franz-Josef, Löffler, Michaela, Wilbs, Marku, Hoehne, Claudia, Ulrici, Johanna, Goeters, Christiane, Flinspach, Armin, Klages, Matthia, Lindau, Simone, Messroghli, Leila, Zacharowski, Kai, Eisner, Christoph, Mueller, Thoma, Richter, Daniel, Schäfer, Melanie, Weigand, Marku, Weiterer, Sebastian, Ochsenreiter, Miriam, Schöler, Michael, Terboven, Tom, Eggemann, Isabel, Haussmann, Sascha, Leister, Nicola, Menzel, Christoph, Trieschmann, Uwe, Yücetepe, Sirin, Keilig, Susanna, Kranke, Peter, Jelting, Yvonne, Baehner, Torsten, Ellerkmann, Richard, Ghamari, Shahab, Neumann, Claudia, Söhle, Martin, Chloropoulou, Pelagia, Ntritsou, Vagia, Papagiannopoulou, Pinelopi, Garini, Eleana, Karafotia, Afroditi, Mammi, Panagoula, Bali, Evangelia, Iordanidou, Despoina, Malisiova, Anna, Polyzoi, Artemi, Tsiotou, Adelai, Sapi, Erzsebet, Székely, Edgar, Kosik, Nandor, Maráczi, Veronika, Schnur, Jano, Csillag, Judit, Gál, Jáno, Göbl, Gergely, Hauser, Baláz, Petróczy, Andrá, Tövisházi, Gyula, Blain, Stuart, Gallagher, Sarah, Harte, Sinead, Jackson, Mandy, Meehan, Emma, Nawoor, Zeenat, O’Hare, Brendan, Ross, Mark, Lerro, Daniela, Astuto, Marinella, Grasso, Chiara, Scalisi, Rita, Frasacco, Giulia, Lenares, Elena, Leone, Roberto, Grazzini, Maurizia, Minardi, Carmelo, Zadra, Nicola, Cinnella, Gilda, Cotoia, Antonella, Galante, Dario, De Lorenzo, Brita, Kuppers, Beate, Bottazzi, Giulia, Caramelli, Fabio, Mondardini, Maria Cristina, Rossetti, Emanuele, Picardo, Sergio, Vittori, Alessandro, Camporesi, Anna, Wolfler, Andrea, Calderini, Edoardo, Colantonio, Laura Brigitta, Finamore, Simona Anna, Porro, Giuliana Anna, Bonfiglio, Rachele, Kotzeva, Svetlana, Mameli, Leila, Mattioli, Girolamo, Micalizzi, Camilla, Montaguti, Alessia, Pistorio, Angela, Zanaboni, Clelia, Guddo, Anna, Neba, Gerald Rogan, Favarato, Moreno, Locatelli, Bruno Guido, Maffioletti, Micol, Sonzogni, Valter, Garra, Rossella, Sammartino, Maria, Sbaraglia, Fabio, Cortegiani, Andrea, Moscarelli, Alessandra, Attanasi, Elena, Tesoro, Simonetta, Agapiti, Cristina, Pinzoni, Francesca, Vezzoli, Cesare, Bilotta, Federico, Barzdina, Arta, Straume, Zane, Zundane, Anda, Lukosiene, Laura, Maraulaite, Irena, Razlevice, Ilona, Schmitz, Bernd, Mifsud, Stephanie, Aehling, Carolin, Allison, Celia, De Boer, Rient, Emal, Dina, Stevens, Marku, Buitenhuis, Marielle, de Graaff, Jurgen, De Liefde, Inge, Machotta, Andrea, Scoones, Gail, Staals, Lonneke, Tomas, Jeremy, Van der Knijff-van Dortmont, Anouk, Veldhuizen, Marianne, Alders, David, Buhre, Wolfgang, Schafrat, Eva, Schreiber, Jan, Vermeulen, Petronella Mari, Hendriks, Mark, Lako, Sandra, Voet-Lindner, Marieke, Pieters, Barbe, Scheffer, Gert-Jan, Tielens, Luc, Absalom, Anthony R., Bergsma, Margot, De Ruiter, Joke, Meier, Sascha, Volkers, Martin, Zweers, Tjerk, Beukers, Anne M., Boer, Christa, Dertinger, Jurgen, Numan, Sandra, Van Zaane, Ba, Boerke, Wenche B., Ekiz, Nil, Stensrud, Kristoffer, Drage, Inger Marie, Isern, Erik Ramon, Bartkowska-Sniatkowska, Alicja, Grzeskowiak, Malgorzata, Juzwa-Sobieraj, Magdalena, Rosada-Kurasińska, Jowita, Baranowski, Artur, Jakubowska, Karina, Lewandowska, Dorota, Mierzewska-Schmidt, Magdalena, Sawicki, Piotr, Urban-Lechowicz, Magdalena, Przemyslaw, Pomianek, Zielinska, Marzena, Leal, Teresa, Soares, Maria, Pina, Pedro, Pinho, Sílvia, Patuleia, Maria Dominga, Esteves, Catarina Cruz, Salgado, Helena, Santos, Maria João, Badeti, Rodica, Cindea, Iulia, Oana, Loredana, Gurita, Adriana, Ilie, Luminita, Mocioiu, Gabriel, Tabacaru, Radu, Trante, Irina, Munteanu, Valentin, Morariu, Mihai, Nyíri, Emese, Budic, Ivana, Marjanovic, Vesna, Drašković, Biljana, Pandurov, Marina, Ilic, Jordanka, Mandras, Ana, Rados, Zdenka, Stankovic, Nikola, Suica, Maja, Vasiljevic, Sladjana, Knezevic, Mirjana, Milojevic, Irina, Petrov, Ivana, Puric Racic, Selena, Simic, Dusica, Simic, Irena, Stevic, Marija, Vulicevic, Irena, Cabanová, Barbora, Hanula, Miloslav, Berger, Jelena, Janjatovic, Darja, Pirtovšek Štupnik, Špela, Méndez, Dolore, Pino, Gema, Rubio, Paloma, Izquierdo, Alberto, López, Silvia, González Serrano, Cristina, Cebrián, Jesú, Peleteiro, Ana, Del Rey de Diego, Pilar, Martínez García, Ernesto, Tormo de las Heras, Carolina, Troncoso Montero, Pablo, Arbona, Celia, Artés, David, Chamizo, Alicia, Serrano, Silvia, Suarez Comas, Montserrat, Escribá, Francisco, Auli, Cristina, Pérez Pardo, Osvaldo, Sierra Biddle, Natalia, Suárez Castaño, Ceferina, Villalobos Rico, María Isabel, Manrique Muñoz, Susana, García Martínez, Irene, Montferrer Estruch, Nuria, Vilardell Ortíz, Elena, Poves-Álvarez, Rodrigo, Kohn, Ivan, Lindestam, Ulf, Reinhard, Jarl, Castellheim, Albert, Sandström, Kerstin, Bengt, Sporre, Dörenberg, Rainer, Frykholm, Peter, Garcia, Maria, Kvarnström, Ann, Pontén, Emma, Bruelisauer, Thoma, Erdoes, Gabor, Kaiser, Heiko, Marchon, Mathia, Seiler, Stefan, Bögli, Yann, Dolci, Mirko, Marcucci, Carine, Pichon, Isabelle, Vutskits, Laszlo, Casutt, Mattia, Hölzle, Martin, Hurni, Thoma, Jöhr, Martin, Malär, Anna-Ursina, Mauch, Jacqueline, Erb, Thoma, Oeinck, Karin, Akin, Mine, Keskin, Gulsen, Senayli, Yesim, Kaya, Guner, Kendigelen, Pinar, Tutuncu, Ayse Çiğdem, Hatipoğlu, Zehra, Özcengiz, Dilek, Erdost, Hale Aksu, Öçmen, Elvan, Olguner, Çimen, Ayanoglu, Hilmi, Dincer, Pelin Corman, Umuroglu, Tumay, Azizoglu, Mustafa, Birbiçer, Handan, Doruk, Nurcan, Sagun, Aslı, Baris, Sibel, Dmytriiev, Dmytro, Kuchi, Sridevi, Masip, Nuria, Brooks, Peter, Hare, Alison, Ahmad, Nargi, Casey, Michelle, De Silva, Sam, Dobby, Nadine, Krishnan, Prakash, Sogbodjor, L. Amaki, Walker, Ellie, Walker, Suellen, King, Stephanie, Nicholson, Katy, Quinney, Michelle, Stevens, Paul, Blevin, Andrew, Giombini, Mariangela, Goonasekera, Chulananda, Adil, Sadia, Bew, Stephanie, Bodlani, Carol, Gilpin, Dan, Jinks, Stephanie, Malarkkan, Nalini, Miskovic, Alice, Pad, Rebecca, Wolfe Barry, Juliet, Abbott, Joy, Armstrong, Jame, Cooper, Natalie, Crate, Lindsay, Emery, John, James, Kathryn, King, Hannah, Martin, Paul, Scalia Catenacci, Stefano, Bomont, Rob, Smith, Paul, Mele, Sara, Verzelloni, Alessandra, Dix, Philippa, Bell, Graham, Gordeva, Elena, McKee, Lesley, Ngan, Esther, Scheffczik, Jutta, Tan, Li-En, Worrall, Mark, Cassar, Carmel, Goddard, Kevin, Barlow, Victoria, Oshan, Vimmi, Shah, Khairi, Bell, Sarah, Daniels, Lisa, Gandhi, Monica, Pachter, David, Perry, Chri, Robertson, Andrew, Scott, Carmen, Waring, Lynne, Barnes, David, Childs, Sophie, Norman, Joanne, Sunderland, Robin, Julia, Dowell, Prisca, Feijten, Pierre, Harlet, Sarah, Herbineaux, Brigitte, Leva, Benoît, Plichon, Katalin, Virág, IOO, ACS - Microcirculation, APH - Quality of Care, and ANS - Neuroinfection & -inflammation

Subjects
Male, Time Factors, paediatric, medicine.medical_treatment, morbidity, Severity of Illness Index, 0302 clinical medicine, 030202 anesthesiology, Risk Factors, Clinical endpoint, Anesthesia, Prospective Studies, 610 Medicine & health, Hypoxia, Medical Audit, medicine.diagnostic_test, ddc:617, infants, Incidence (epidemiology), Incidence, Age Factors, anaesthesia, respiratory system, Europe, Treatment Outcome, Cohort, Female, medicine.symptom, Bradycardia, Laryngoscopy, Anesthesia/adverse effects/mortality, Risk Assessment, Europe/epidemiology, 03 medical and health sciences, Laryngoscopy/adverse effects/mortality, Hypoxia/diagnosis/epidemiology/mortality, medicine, Intubation, Intratracheal, Humans, difficult intubation, business.industry, Tracheal intubation, Infant, Newborn, Infant, Perioperative, Newborn, 3126 Surgery, anesthesiology, intensive care, radiology, mortality, neonates, Clinical trial, Intratracheal, Anesthesiology and Pain Medicine, airway, Intubation, Intratracheal/adverse effects/mortality, neonate, Intubation, business, airways
Abstract

Background: Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences. Methods: We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes. Results: Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1e6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO2

Published
2021
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44. Multi‐criteria decision‐making approach for modular enterprise resource planning sorting problems

Author

Marco La Cascia, Antonella Certa, Silvia Carpitella, Joaquín Izquierdo, Carpitella S., Certa A., Izquierdo Sebastian J., and La Cascia M.

Subjects
Operations research, Computer science, business.industry, Strategy and Management, Usability, Maintainability, Sorting, General Decision Sciences, Modular design, Multiple-criteria decision analysis, Multi criteria decision, Enterprise resource planning, ELECTRE TRI, MATEMATICA APLICADA, business, MCDM
Abstract

[EN] Implementing Enterprise Resource Planning (ERP) systems is currently recognized as a best practice with wide associated possibilities of business improvement for companies. Integrating these kinds of systems with business processes in the most efficient way requires to endeavour as much as possible simplifications for final users, which can be pursued by optimizing crucial software characteristics. The present article proposes a novel Multi-Criteria Decision-Making (MCDM) approach to deal with such an issue. Specifically, the ELECTRE (ELimination Et Choix Traduisant la REalite) TRI technique is suggested to assign ERP modules into predefined and ordered categories according to maintainability and usability, which are useful drivers in evaluating which module of an ERP software should be enhanced with priority. The results prove to have whole beneficial impact on system performance with relation to a case study: improvement evaluations will be identified based on the classes the ERP modules are assigned to by the method.

Published
2021
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45. Utilization of coal fly ash from a Chinese power plant for manufacturing highly insulating foam glass: Implications of physical, mechanical properties and environmental features

Author

Lia, Jing, Zhuang, Xinguo, Monfort, Eliseo, Querol, Xavier, Llaudis, Alejandro Saburit, Font, Oriol, Moreno, Natalia, Ten, Francisco Javier Garcia, and Izquierdo, Maria

Subjects
Electric power plants -- Mechanical properties, Combustion -- Mechanical properties, Raw materials -- Mechanical properties, Fly ash -- Mechanical properties -- Chemical properties -- Analysis, Business, Construction and materials industries
Abstract

ABSTRACT This research focuses on the potential use of fly ash (WAf) from a Chinese pulverized-coal combustion (PCC) power plant for manufacturing foam glass. The influences of fly ash properties, [...]

Published
2018
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46. Towards storage-stable high-content recycled tyre rubber modified bitumen

Author

Presti, D. Lo, Izquierdo, M.A., and del Barco Carrion, A. Jimenez

Subjects
Bituminous materials -- Thermal properties -- Mechanical properties -- Analysis, Rheology -- Analysis, Temperature -- Analysis, Business, Construction and materials industries
Abstract

ABSTRACT The addition of crumb rubber particles as bitumen modifier can be currently considered as a wellestablished alternative to conventional polymers for bitumen modification. However, Recycle Tyre Rubber (RTR) modified [...]

Published
2018
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47. Cost-effectiveness analysis of anti–IL-5 therapies of severe eosinophilic asthma in Spain

Author

Xavier Muñoz-Gall, Gijs van de Wetering, Shibing Yang, Andrea García, José Luis Izquierdo-Alonso, Francisco-Javier González-Barcala, Esther Mariscal, Institut Català de la Salut, [González-Barcala FJ] Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain. Respiratory Medicine, Universidad de Santiago de Compostela, Santiago de Compostela, Spain. [Muñoz-Gall X] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. CIBER of Respiratory Diseases (CIBERes), Madrid, Spain. Departament de Biologia Cel•lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Mariscal E, García A] GlaxoSmithKline, Madrid, Spain. [Yang S] GlaxoSmithKline, Collegeville, PA, USA. [van de Wetering G] Pharmerit International, Rotterdam, the Netherlands. [Izquierdo-Alonso JL] Medicine and Specialities Department, Universidad de Alcalá (Alcalá de Henares, Madrid), Hospital Universitario Guadalajara, Guadalajara, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
medicine.medical_specialty, Standard of care, Cost effectiveness, Cost-Benefit Analysis, Eosinophilic asthma, 03 medical and health sciences, 0302 clinical medicine, Adrenal Cortex Hormones, Internal medicine, Eosinophilia, economía y organizaciones para la atención de la salud::economía::costes y análisis de costes::análisis coste-beneficio [ATENCIÓN DE SALUD], medicine, hormonas, sustitutos de hormonas y antagonistas de hormonas::hormonas::hormonas de la corteza suprarrenal [COMPUESTOS QUÍMICOS Y DROGAS], Humans, Other subheadings::/therapeutic use [Other subheadings], Eosinofília, health care economics and organizations, enfermedades hematológicas y linfáticas::enfermedades hematológicas::trastornos leucocitarios::eosinofilia [ENFERMEDADES], Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones [CHEMICALS AND DRUGS], Otros calificadores::/uso terapéutico [Otros calificadores], business.industry, 030503 health policy & services, Health Policy, Cost-effectiveness analysis, Asthma, Anti il 5, Hormones esteroides - Ús terapèutic, Health Care Economics and Organizations::Economics::Costs and Cost Analysis::Cost-Benefit Analysis [HEALTH CARE], Spain, 030220 oncology & carcinogenesis, Cost-eficàcia, Hemic and Lymphatic Diseases::Hematologic Diseases::Leukocyte Disorders::Eosinophilia [DISEASES], Quality-Adjusted Life Years, 0305 other medical science, business, Mepolizumab, medicine.drug
Abstract

Asma eosinofílica greu; Comparació indirecta del tractament; Mepolizumab Severe eosinophilic asthma; Indirect treatment comparison; Mepolizumab Asma eosinofílica severa; Comparación de tratamiento indirecto; Mepolizumab Aim To analyse the cost-effectiveness of MEP with standard of care (SoC) versus other anti-IL-5 therapies approved for the treatment of severe eosinophilic asthma (SEA) patients, within the Spanish National Health System (NHS) perspective. Methods A Markov model with a 4-week cycle length was used to compare MEP with BEN and RES as therapies added to SoC in the management of SEA, in terms of cost per QALY gained and incremental cost-effectiveness ratio (ICER). Costs (€2019) were obtained from public sources, while utilities and transition probabilities were retrieved from literature, e.g. network meta-analysis. Continuation criteria for biological treatment and reduction of oral corticosteroids (OCS) was set at 50% minimum reduction of exacerbation rate. Adverse events related to chronic OCS use included diabetes, osteoporosis, cataracts, acute myocardial infarct, and peptic ulcer. The analysis was performed over a 5-year time horizon from the National Healthcare System (NHCS) perspective, with a yearly discount rate of 3% applied to both costs and QALYs. Probabilistic sensitivity analysis and univariate deterministic sensitivity analysis were performed to address uncertainty around the cost-effectiveness results. Results On top of SoC, the model indicates that MEP is dominant (lower cost, higher benefit) compared to BEN and RES: For BEN and RES, respectively, treatment with MEP had a point estimate of 0.076 and 0.075 additional QALYs, and savings of €3,173.47 and €7,772.95 per patient. The findings were robust to variation as estimated using sensitivity analysis. Conclusions MEP is a cost-effective treatment in comparison with BEN and RES added to SoC for patients with SEA in the Spanish setting. This study was funded by GlaxoSmithKline [Study code: HO-19-19968].

Published
2021
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48. Manufacturing, Developments, and Constraints in Full 3-D Printing of Frequency-Selective Surface Using Low-Cost Open-Source Printer

Author

A. Elibiary, A. Shastri, Benito Sanz-Izquierdo, and Edward A. Parker

Subjects
Fabrication, Computer science, business.industry, Plastics extrusion, TK7800, Mechanical engineering, 3D printing, Fused filament fabrication, Substrate (printing), Signal, Industrial and Manufacturing Engineering, Electronic, Optical and Magnetic Materials, TK5101, Electrical and Electronic Engineering, Center frequency, business, Electrical conductor
Abstract

A comprehensive study of developing a novel printing system using a low-cost open-source printer for fully 3D printing frequency selective surface is presented in this paper. The novel printing setup employs a low-cost printer to print a plastic based filament and a conductive silver ink paste simultaneously. As there were no printers available in the market for this application, the open-source Fused Filament Fabrication (FFF) printer was modified to accommodate two extruders mounted on the same extruder carriage. Techcon TS250 air pressure dispenser was employed for the extrusion of silver ink. Extension pieces for the extruder carriage were also 3D printed using a Fused Deposition Modelling (FDM) printer to reduce the production costs. A bandstop FSS comprising of square loop elements was designed to demonstrate the full fabrication. The FSS operated at a central frequency of 2.55 GHz and provided a good angle of response with wide bandwidths. Surface profiles of the printed FSS and substrate demonstrate the reliable fabrication of the FSS design. This full 3D printing method provides an economical, eco-friendly, swift, reliable, and viable substitute for the fabrication of FSS designs that could be highly customised in terms of fabricating three-dimensional FSS designs with reliable performances. The designs can be printed and deployed to reduce the drop in signal within an enclosed environment.

Published
2021
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50. Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Segmentation

Author

Campello, Victor M., Gkontra, Polyxeni, Izquierdo, Cristian, Martin-Isla, Carlos, Sojoudi, Alireza, Full, Peter M., Maier-Hein, Klaus, Zhang, Yao, He, Zhiqiang, Ma, Jun, Parreno, Mario, Albiol, Alberto, Kong, Fanwei, Shadden, Shawn C., Corral Acero, Jorge, Sundaresan, Vaanathi, Saber, Mina, Elattar, Mustafa, Li, Hongwei, Menze, Bjoern, Khader, Firas, Haarburger, Christoph, Scannell, Cian M., Veta, Mitko, Carscadden, Adam, Punithakumar, Kumaradevan, Liu, Xiao, Tsaftaris, Sotirios A., Huang, Xiaoqiong, Yang, Xin, Li, Lei, Zhuang, Xiahai, Viladés Medel, David, Descalzo, Martin, Guala, Andrea, Mura, Lucía La, Friedrich, Matthias G., Garg, Ria, Lebel, Julie, Henriques, Filipe., Karakas, Mahir, Cavus, Ersin, Petersen, Steffen E., Escalera, Sergio, Segui, Santi, Rodriguez-Palomares, Jose F.., Lekadir, Karim, Universitat Autònoma de Barcelona, Medical Image Analysis, and EAISI Health

Subjects
Computer science, Processament digital d'imatges, computer.software_genre, SDG 3 – Goede gezondheid en welzijn, Field (computer science), 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Resource (project management), Segmentation, Cardiac imaging, Image segmentation, domain adaption, Radiological and Ultrasound Technology, Heart, Benchmarking, Magnetic Resonance Imaging, Hospitals, Computer Science Applications, Generalizability, Domain adaption, Biomedical engineering, data augmentation, Data augmentation, Machine learning, 03 medical and health sciences, Magnetic resonance imaging, SDG 3 - Good Health and Well-being, Imatges per ressonància magnètica, Aprenentatge automàtic, Humans, Training, Generalizability theory, Electrical and Electronic Engineering, generalizability, business.industry, Deep learning, deep learning, Public dataset, public dataset, Cardiac Imaging Techniques, Cardiovascular magnetic resonance, Artificial intelligence, business, computer, Digital image processing, Software, Protocols
Abstract

The emergence of deep learning has considerably advanced the state-of-the-art in cardiac magnetic resonance (CMR) segmentation. Many techniques have been proposed over the last few years, bringing the accuracy of automated segmentation close to human performance. However, these models have been all too often trained and validated using cardiac imaging samples from single clinical centres or homogeneous imaging protocols. This has prevented the development and validation of models that are generalizable across different clinical centres, imaging conditions or scanner vendors. To promote further research and scientific benchmarking in the field of generalizable deep learning for cardiac segmentation, this paper presents the results of the Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Segmentation (M&Ms) Challenge, which was recently organized as part of the MICCAI 2020 Conference. A total of 14 teams submitted different solutions to the problem, combining various baseline models, data augmentation strategies, and domain adaptation techniques. The obtained results indicate the importance of intensity-driven data augmentation, as well as the need for further research to improve generalizability towards unseen scanner vendors or new imaging protocols. Furthermore, we present a new resource of 375 heterogeneous CMR datasets acquired by using four different scanner vendors in six hospitals and three different countries (Spain, Canada and Germany), which we provide as open-access for the community to enable future research in the field.

Published
2021

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