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Objective We aimed to reveal whether there is nasal involvement by examining the Nasal Mucociliary Clearance (NMC) and the relationship between this activity and disease severity in Rheumatoid Arthritis (RA) patients. Methods In this prospective study, NMC time, disease activity (Disease Activity Score 28) and blood parameters of RA patients (n = 87) were investigated and compared with the healthy control group (n = 50). In addition, the relationship between DAS 28 and NMC was investigated. Results The mean NMC of the RA group was 9.51 ± 3.54 min, the mean NMC of the control group was 8.69 ± 2.85 min, and there was no significant difference between the two groups. There was no correlation between NMC and disease duration, and DAS 28. The mean NMC of the RA patients with Anti Cyclic Citrulled Peptide (Anti-CCP) positive was significantly higher than the negative ones. Conclusion Although there was no significant difference in NMC values between the RA and control group, the NMC of the Anti-CCP positive patients was higher. Level of evidence Level 2.

Background: We aimed to evaluate whether C-reactive protein(CRP)/ Albumin ratio (CAR) performed in the early postoperative period after total laryngectomy could be a predictive factor for the development of pharyngocutaneous fistula (PCF). Methods: The files of patients with laryngeal squamous cell carcinoma who underwent total laryngectomy between January 2005 and January 2019 were retrospectively reviewed. Patients were divided into two groups: patients with PCF (PCF group) and without (Non-PCF group). CAR values and risk factors were compared between groups. Results: The overall incidence of PCF was 23.2%. There was a statistically significant difference between the two groups in terms of CRP and CAR levels (p = 0.001). The CAR value of 27.05 (sensitivity = 75.0% , specificity 68.2%, area under curve (AUC) = 0.742, 95% confidence interval 0.616–0.868) was determined as a cutoff value to describe the development of fistula in the early postoperative period. In multiple linear regression analysis, there was an independent relationship between presence of PCF and previous RT and CAR value. Conclusions: CAR, performed in the early postoperative period, may be a new and useful marker for predicting PCF after total laryngectomy.

PubMed ID: 31129457 Objectives: To investigate the changes in the risk factors affecting the results of the Newborn Hearing Screening (NHS) and the hearing test results of the Syrian refugees in our city. Methods: Syrian and Turkish newborns, born in our hospital between 01.01.2016 and 31.12.2017 and referred to our hospital from environmental hospitals for NHS, were included in this study. NHS results and risk factors were analyzed. Results: 786 Syrian and 7230 Turkish newborns were included in this study. 53 (6,74%) infants referred in both ears, 26 (3,30%) infants in the one ear. There was a significant relationship between the presence of hearing loss and the history of intensive care unit admittance, presence and absence of low birth weight and neonatal icterus at Syrian newborns. In the same period, 20 (0,3%) Turkish infants referred bilaterally and 45 (0,6%) newborns unilaterally (25 right ear, 20 left ear). There was a significant difference between Turkish and Syrian newborns in terms of very low and low birth weight and intensive care unit admittance. Conclusions: The rate of hearing loss in Syrian refugee patients is quite high. Pregnant refugee women who are forced to migrate because of war face many risk factors and these people need to be included into the newborn hearing screening programs in the country where they took refuge in. © 2019 Elsevier B.V.

Lipomlar vücudun her yerinde görülebilen benign mezenkimal tümörlerdir. Lipomların %25'i baş-boyun bölgesinde görülür ve bunların çoğu posterior servikal üçgende yerleşir. On cm'den daha uzun veya 1000 gramdan daha ağır olan lipomlara dev lipom denir. Servikotorasik lipomlar oldukça nadirdir ve şu ana kadar literatürde dört olgu bildirilmiştir. Bu raporda biz, orta juguler üçgenden başlayıp ön servikal üçgene ve mediastinuma uzanan dev bir lipomun torakotomi yapılmadan başarılı bir şekilde eksizyonunu sunduk., Lipomas are benign mesenchymal tumors that can be observed all over the body. In total, 25% of lipomas are observed in the head and neck region, and most of them are located in the posterior cervical triangle. Lipomas that are greater than 10 cm in width or more than 1000 g in weight are called giant tumors. Cervico–thoracic lipomas are extremely rare, and only four cases have been reported in the English literature. We report successful surgical excision of a giant lipoma, which started from middle-anterior cervical region covered the anterior cervical triangle, and extended to the mediastinum, without thoracotomy.

Transnasal penetrating brain injuries are rare and a medical emergency, which needs to be treated promptly. A 4-year-old male patient was brought to our emergency room with a knife sticking out of his nose. The patient was immediately taken to the operating room and the knife was removed under general anesthesia. No cerebrospinal fluid leakage or any bleeding was seen and so the operation was terminated. The authors herein report a penetrating brain trauma through to the cella turcica with a knife that improved without any sequelae at a child.

WOS:000365356700012, PubMed ID: 29391978, Baş-boyun bölgesinden kaynaklanan dermoid kistler nadir, yavaş büyüyen ve iyi sınırlı benign tümörlerdir. Semptomları, özgün değildir, genellikle lezyonun boyutu ve bulunduğu yere bağlıdır. Epiglottan kaynaklı dermoid kist son derece nadirdir. Bilgimiz dahilinde, İngilizce literatürde sadece bir olgu rapor edilmiştir. Bu çalışmada, epiglottan kaynaklanan bir dermoid kist olgusu çok nadir bir klinik durum olarak sunulmuştur. Hastalığın karakteristikleri, ayırıcı tanısı ve tedavi yöntemleri özetlenmiştir., Dermoid cysts arising from the head and neck region are rare, slow-growing, and well-circumscribed neoplasms. Symptoms are non-specific and usually related to the size and the location of the lesion. A dermoid cyst of the epiglottis is extremely rare. To the best of our knowledge, only one case has been previously reported in the English literature. In this study, a case of a dermoid cyst arising from the epiglottis was presented as an extremely rare clinical condition. The characteristics, differential diagnosis, and treatment of the disease are summarized.