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Articular distal radius fractures (DRFs) have increased in incidence in recent years, especially among the economically active population. Most of the treatment approaches are based on plain X- rays, and do not give us any information on how to treat these fractures. In the search for solutions with greater precision in diagnosis, in reducing the joint surface of the fracture, and envolving minimally-invasive techniques, we found arthroscopy as the main tool for these patients. Therefore, an enhanced understanding of the biomechanics of the different types of fracture associated with ligamentous lesions should facilitate the right decision regarding the treatment. The present paper aims at providing a management-oriented concept to diagnose and treat ligamentous lesions associated with intra-articular DRFs based on a arthroscopy-assisted procedure, and showing the objective and patient-reported outcomes and a new classification. The objective and patient-reported outcomes were: the mean range of motion (ROM) was of 94.80% on the non-affected side; the mean score on the abbreviated version of the Disabilities of the Arm, Shoulder and Hand questionnaire (QuickDASH) was of 3.6 (range: 1 to 12). The score on the Visual Analog Scale (VAS) was of 1.66 (range: 1 to 3). Complications were observed in 2 (13.33%) patients: extensor tendon synovitis in 1 patient, and a limitation (stiffness) in ROM in 1 patient, both treated with wrist arthroscopy release. The mean time until the return to work was of 6.4 weeks. In patients with unstable intra-articular DRFs associated with ligamentous lesions, the fixation of specific osseous-ligamentous fragments and ligamentous repair/reconstruction by wrist arthroscopy prove to be a safe and reliable treatment. The clinical and functional results predict that the patients can return to work more quickly.

Gliosarcoma, a variant of glioblastoma, is a rare and aggressive tumor of the central nervous system (CNS) composed of glial and sarcomatous tissues. Up to now, there are only 2 reported cases of gliosarcoma of the optical pathway. We report a case from March 2018 of a 53-year-old male patient presented with 6 months’ of right fronto-orbital pulsatile headache, behavior changes, and visual loss. The MRI study showed an expansile optic pathway lesion involving the chiasm and right optic nerve. The diagnosis of gliosarcoma was obtained by open brain biopsy and immunohistochemical analysis. Although gliosarcoma is rare, it should be considered a differential diagnosis even in optic pathway tumors in older patients. The experience of the neuropathologist with a trained eye can be the differential in the accurate diagnostic process. Optic pathway, Gliosarcoma, Glioblastoma, Magnetic resonance imaging

Spinal dysraphisms (SDs) are congenital malformations of the spinal cord, determined by derangement in the complex cascade of embryologic events involved in spinal development. They represent a heterogeneous group ranging from mild clinical manifestations-going unnoticed or being discovered at clinical examination-to a causal factor of life quality impairment, especially when associated with musculoskeletal, gastrointestinal, genitourinary, or respiratory system malformations. Knowledge of the normal embryologic development of the spinal cord-which encompasses three main steps (gastrulation, primary neurulation, and secondary neurulation)-is crucial for understanding the pathogenesis, neuroradiologic scenarios, and clinical-radiologic classification of congenital malformations of the spinal cord. SDs can be divided with clinical examination or neuroradiologic study into two major groups: open SDs and closed SDs. Congenital malformations of the spinal cord include a wide range of abnormalities that vary considerably in imaging and clinical characteristics and complexity and therefore may represent a diagnostic challenge, even for the experienced radiologist.

Efficient recovery and utilization of valuable components from industrial food side streams is a main driver towards a circular economy. Among different available purification techniques, adsorption can effectively recover these components. However, the conventional batch mode of operation can limit its applicability in food processes due to limited efficiency. This work compares conventional batch packed bed adsorption with semi-continuous adsorption (so-called CaptureSMB) for the recovery of sinapic acid at industrial scale, using a food grade resin AmberliteTM FPX66. A mathematical mechanistic model able to describe semi-continuous operation is successfully validated and used to identify optimum operating parameters to maximize productivity and resin capacity utilization in batch and semi-continuous operating modes. The results indicate that CaptureSMB outperforms batch operation, increasing productivity from 5.18 g/L/h to 10.3 g/L/h for a given yield (>97%). A resin capacity utilization (RU) of around 70% is observed in both operating modes when productivity is maximized. A 92% RU can be accomplished for a given yield using the CaptureSMB process at a productivity of 7.0 g/L/h, higher than for conventional batch operation. The use of semi-continuous adsorption operation in food industry contributes to more efficient processes at reduced purification costs.

Con el objetivo de determinar la tasa y factores relacionados con peritonitis en pacientes de una unidad de diálisis peritoneal (DP) atendidos en un hospital de Lima, Perú, se realizó un estudio retrospectivo de cohorte única durante el periodo de 2014 a 2016. Se incluyó a todos los pacientes con diagnóstico de enfermedad renal crónica del programa de DP del Hospital Cayetano Heredia. Se estimó la tasa de incidencia de peritonitis y se realizó un análisis bivariado para evaluar los factores relacionados. Se incluyó un total de 73 pacientes. La tasa de incidencia de peritonitis fue de 0,60 episodios por paciente al año; el 46,7% de los cultivos fueron positivos siendo el germen aislado más común el S. aureus. Los factores relacionados con peritonitis fueron menor valor de albúmina y hematocrito. La tasa de incidencia de peritonitis y de cultivos negativos se encontraron por encima del valor sugerido internacionalmente.

The scientific novelty of this research lies in the integrating conception of the management audit, the social responsibility approach and its relationships expressed in a conceptual model that defines lines of action for management, which is operationalized through the methodological and practical construction of a management audit procedure with a social responsibility approach that allows the identification and management of indicators associated with the social behavior of an organization. This research was supported with the use of open source tools.

As combinações entre as necessidades dos entornos sociais, governamentais e empresariais geram novos mode­los de desenvolvimento que fazem links entre situações tradicionais e atuais, dando como resultados novos cenários que oferecem interações peer-to-peer para gerar um mix de soluções nas quais o benefício é mutuo. “Minuteros” apresenta a análise de um modelo de serviço de comunicação que além de gerar renda e suscitar aproximações entre usuários, aproveita tecnologia em desuso com ciclos de vida adicionais como caminho para a sustentabilidade..ABSTRACT The combinations between the needs of the corporate, government and corporate environments generate new develop­ment models that make links between traditional and current situations, giving as results new scenarios that offer peer-to-peer interactions to generate a mix of solutions in which the benefit is mutual. "Minuteros" presents the analysis of a communication service model that besides generating income and raise similarities between users, leverages technology into disuse with addi­tional life cycles as a path to sustainability.

The conceptual design of a bio-based process for 2-butanol production is presented for the first time. Considering a hypothetical efficient producing strain, a vacuum fermentation is proposed to alleviate product toxicity, but the main challenge is the energy-efficient product recovery from the vapor. Three downstream scenarios were examined for this purpose: 1) multi-stage vapor recompression; 2) temperature swing adsorption; and 3) vapor absorption. The processes were simulated using Aspen Plus, considering a production capacity of 101 kton/yr. Process optimization was performed targeting the minimum selling price of 2-butanol. The feasibility of the different configurations was analyzed based on the global energy requirements and capital expenditure. The use of integrated adsorption and absorption minimized the energy duty required for azeotrope purification, which represents 11% of the total operational expenditure in Scenario 1. The minimum selling price of 2-butanol as commodity chemical was estimated as 1.05 $/kg, 1.21 $/kg, and 1.03 $/kg regarding the fermentation integrated with downstream scenarios 1), 2), and 3), respectively. Significant savings in 2-butanol production could be achieved in the suggested integrated configurations if more efficient microbial strains were engineered, and more selective adsorption and absorption materials were found for product recovery.

This paper presents the results of a comparative study of digital segmentation methods and analog methods - digital segmentation. The spectral images were acquired with an acousto-optic system, which allows the acquisition of grayscale pictures in a narrow range of wavelengths. The series of images acquired for the entire visible spectrum, allows simple digital operations, perform segmentation processes. The segmentation is based on the analysis of spectral components over regions of the image. This type of processing is compared with traditional digital processing. The experimental results demonstrate that the segmentation processes developed with the acousto-optical system in conjunction with digital techniques of image processing, reduce the computational cost without compromise the quality of the segmentation.