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1. POS0264 THE EMERGING ROLE OF MAGNETIC RESONANCE IMAGING IN INTERSTITIAL LUNG DISEASE IN SYSTEMIC SCLEROSIS: EVIDENCE FOR ULTRA SHORT TE AND COMPRESSED SENSING VIBE ACQUISITIONS AS PROMISING TOOLS FOR THE EVALUATION OF PARENCHYMAL ALTERATIONS

Author

Lorenzo Tofani, Nicholas Landini, M. Matucci-Cerinic, Silvia Bellando-Randone, Martina Orlandi, C. Nardi, G. Morana, Stefano Colagrande, Mariaelena Occhipinti, and C. Bruni

Subjects
medicine.medical_specialty, medicine.diagnostic_test, business.industry, Immunology, Interstitial lung disease, Magnetic resonance imaging, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Rheumatology, Parenchyma, medicine, Immunology and Allergy, Radiology, business
Abstract

Background:Interstitial lung disease (ILD) is a frequent complication and the major cause of death in Systemic sclerosis (SSc). Computed tomography (CT) is the gold standard imaging technique to assess ILD but is burdened by exposure to ionizing radiations that limits its use for the follow-up. MRI sequences with Ultra Short Echo Time (UTE) are promising for ILD.Objectives:We tested two MRI sequences, UTE Spiral VIBE and Compressing Sensing (CS) VIBE, in SSc-ILD, in comparison to chest CT.Methods:SSc patients with suspected-ascertained ILD were evaluated for undergoing CT-MRI examinations in the same day. Two radiologists visually scored the extent of ground glass opacities (GGO), reticulations, honeycombing and consolidations on CT-MRI. The sum of alteration was assumed as ILD extent. A quantitative texture analysis (qCT) was also performed on CT. Cohen’s k was adopted for interreader concordance in ILD detection. MRI sensitivity and specificity in ILD detection were evaluated. Lin’s concordance was adopted to compare extent analysis between readers and between CT (visual and qCT analysis) and MRI sequences.Results:54 patients performed both CT and MRI. MRI interreader concordance was moderate in ILD detection, while ILD and GGO extent analysis showed good or very good concordance. UTE Spiral VIBE had a sensitivity and specificity in ILD detection of 95.8% and 77.8%, while alterations extent analysis obtained a very good concordance with CT for ILD and GGO. CS VIBE showed a sensitivity and specificity in ILD detection of 46.7% and 95.0%, but a slight or fair concordance with CT in all alterations’ extent analysis.Conclusion:MRI UTE Spiral VIBE sequences are helpful in the evaluation of SSc-ILD. Larger cohorts of patients will be needed to confirm that MRI may be useful in clinical practice, reducing the radiological load of chest CTReferences:[1]Romei C, Turturici L, Tavanti L, et al. The use of chest magnetic resonance imaging in interstitial lung disease: a systematic review. Eur Respir Rev. 2018;27(150):180062. Doi:10.1183/16000617.0062-2018[2]Miller GW, Mugler JP, Sá RC, Altes TA, Prisk GK, Hopkins SR. Advances in functional and structural imaging of the human lung using proton MRI. NMR Biomed. 2014;27(12):1542-1556. doi:10.1002/nbm.3156[3]Pinal-Fernandez I, Pineda-Sanchez V, Pallisa-Nuñez E, et al. Fast 1.5 T chest MRI for the assessment of interstitial lung disease extent secondary to systemic sclerosis. Clin Rheumatol. 2016;35(9):2339-2345. doi:10.1007/s10067-016-3267-0[4]Ohno Y, Koyama H, Yoshikawa T, et al. Pulmonary high-resolution ultrashort TE MR imaging: Comparison with thin-section standard- and low-dose computed tomography for the assessment of pulmonary parenchyma diseases: Pulmonary MRI with UTE in Pulmonary Disease. J Magn Reson Imaging. 2016;43(2):512-532. doi:10.1002/jmri.25008Disclosure of Interests:None declared

Published
2021
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2. MEDULLOBLASTOMA

Author

G. Vaidyanathan, S. Gururangan, D. Bigner, M. Zalutsky, M. Morfouace, A. Shelat, J. Megan, B. B. Freeman, S. Robinson, S. Throm, J. M. Olson, X.-N. Li, K. R. Guy, G. Robinson, C. Stewart, A. Gajjar, M. Roussel, N. Sirachainan, S. Pakakasama, U. Anurathapan, A. Hansasuta, M. Dhanachai, C. Khongkhatithum, S. Hongeng, A. Feroze, K.-S. Lee, S. Gholamin, Z. Wu, B. Lu, S. Mitra, S. Cheshier, P. Northcott, C. Lee, T. Zichner, P. Lichter, J. Korbel, R. Wechsler-Reya, S. Pfister, I. P. T. Project, K. K.-W. Li, T. Xia, F. M. T. Ma, R. Zhang, L. Zhou, K.-M. Lau, H.-K. Ng, L. Lafay-Cousin, S. Chi, J. Madden, A. Smith, E. Wells, E. Owens, D. Strother, N. Foreman, R. Packer, E. Bouffet, T. Wataya, J. Peacock, M. D. Taylor, D. Ivanov, M. Garnett, T. Parker, C. Alexander, L. Meijer, R. Grundy, P. Gellert, M. Ashford, D. Walker, J. Brent, F. Z. Cader, D. Ford, A. Kay, R. Walsh, G. Solanki, A. Peet, M. English, T. Shalaby, G. Fiaschetti, S. Baulande, N. Gerber, M. Baumgartner, M. Grotzer, T. Hayase, Y. Kawahara, M. Yagi, T. Minami, N. Kanai, T. Yamaguchi, A. Gomi, A. Morimoto, R. Hill, S. Kuijper, J. Lindsey, E. Schwalbe, K. Barker, J. Boult, D. Williamson, Z. Ahmad, A. Hallsworth, S. Ryan, E. Poon, R. Ruddle, F. Raynaud, L. Howell, C. Kwok, A. Joshi, S. L. Nicholson, S. Crosier, S. Wharton, K. Robson, A. Michalski, D. Hargrave, T. Jacques, B. Pizer, S. Bailey, F. Swartling, K. Petrie, W. Weiss, L. Chesler, S. Clifford, L. Kitanovski, T. Prelog, B. F. Kotnik, M. Debeljak, M. A. Grotzer, A. Gevorgian, E. Morozova, I. Kazantsev, T. Iukhta, S. Safonova, E. Kumirova, Y. Punanov, B. Afanasyev, O. Zheludkova, W. Grajkowska, M. Pronicki, B. Cukrowska, B. Dembowska-Baginska, M. Lastowska, A. Murase, S. Nobusawa, Y. Gemma, F. Yamazaki, A. Masuzawa, T. Uno, T. Osumi, Y. Shioda, C. Kiyotani, T. Mori, K. Matsumoto, H. Ogiwara, N. Morota, J. Hirato, A. Nakazawa, K. Terashima, T. Fay-McClymont, K. Walsh, D. Mabbott, D. Sturm, P. A. Northcott, D. T. W. Jones, A. Korshunov, S. M. Pfister, M. Kool, C. Hooper, S. Hawes, U. Kees, N. Gottardo, P. Dallas, A. Siegfried, A. I. Bertozzi, A. Sevely, N. Loukh, C. Munzer, C. Miquel, F. Bourdeaut, T. Pietsch, C. Dufour, M. B. Delisle, D. Kawauchi, J. Rehg, D. Finkelstein, F. Zindy, T. Phoenix, R. Gilbertson, J. Trubicka, M. Borucka-Mankiewicz, E. Ciara, K. Chrzanowska, M. Perek-Polnik, D. Abramczuk-Piekutowska, D. Jurkiewicz, S. Luczak, P. Kowalski, M. Krajewska-Walasek, C. Sheila, S. Lee, C. Foster, B. Manoranjan, M. Pambit, R. Berns, A. Fotovati, C. Venugopal, K. O'Halloran, A. Narendran, C. Hawkins, V. Ramaswamy, M. Taylor, A. Singhal, J. Hukin, R. Rassekh, S. Yip, S. Singh, C. Duhman, S. Dunn, T. Chen, S. Rush, H. Fuji, Y. Ishida, T. Onoe, T. Kanda, Y. Kase, H. Yamashita, S. Murayama, Y. Nakasu, T. Kurimoto, A. Kondo, S. Sakaguchi, J. Fujimura, M. Saito, T. Arakawa, H. Arai, T. Shimizu, E. Jurkiewicz, P. Daszkiewicz, M. Drogosiewicz, V. Hovestadt, I. Buchhalter, N. N. Jager, A. Stuetz, P. Johann, C. Schmidt, M. Ryzhova, P. Landgraf, M. Hasselblatt, U. Schuller, M.-L. Yaspo, A. von Deimling, R. Eils, A. Modi, M. Patel, M. Berk, L.-x. Wang, G. Plautz, H. Camara-Costa, A. Resch, C. Lalande, V. Kieffer, G. Poggi, C. Kennedy, K. Bull, G. Calaminus, J. Grill, F. Doz, S. Rutkowski, M. Massimino, R.-D. Kortmann, B. Lannering, G. Dellatolas, M. Chevignard, D. Solecki, P. McKinnon, J. Olson, J. Hayden, D. Ellison, M. Buss, M. Remke, J. Lee, T. Caspary, R. Castellino, M. Sabel, G. Gustafsson, G. Fleischhack, M. Benesch, A. Navajas, R. Reddingius, M.-B. Delisle, D. Lafon, N. Sevenet, G. Pierron, O. Delattre, J. Ecker, I. Oehme, R. Mazitschek, M. Lodrini, H. E. Deubzer, A. E. Kulozik, O. Witt, T. Milde, D. Patmore, N. Boulos, K. Wright, S. Boop, T. Janicki, S. Burzynski, G. Burzynski, A. Marszalek, J. Triscott, M. Green, S. R. Rassekh, B. Toyota, C. Dunham, S. E. Dunn, K.-W. Liu, Y. Pei, L. Genovesi, P. Ji, M. Davis, C. G. Ng, Y.-J. Cho, N. Jenkins, N. Copeland, B. Wainwright, Y. Tang, S. Schubert, B. Nguyen, S. Masoud, A. Lee, M. Willardson, P. Bandopadhayay, G. Bergthold, S. Atwood, R. Whitson, J. Qi, R. Beroukhim, J. Tang, A. Oro, B. Link, J. Bradner, S. G. Vallero, D. Bertin, M. E. Basso, C. Milanaccio, P. Peretta, A. Cama, A. Mussano, S. Barra, G. Morana, I. Morra, P. Nozza, F. Fagioli, M. L. Garre, A. Darabi, E. Sanden, E. Visse, N. Stahl, P. Siesjo, D. Vaka, F. Vasquez, B. Weir, G. Cowley, C. Keller, W. Hahn, I. C. Gibbs, S. Partap, K. Yeom, M. Martinez, H. Vogel, S. S. Donaldson, P. Fisher, S. Perreault, L. Guerrini-Rousseau, S. Pujet, V. Kieffer-Renaux, M. A. Raquin, P. Varlet, A. Longaud, C. Sainte-Rose, D. Valteau-Couanet, J. Staal, L. S. Lau, H. Zhang, W. J. Ingram, Y. J. Cho, Y. Hathout, K. Brown, B. R. Rood, M. Handler, T. Hankinson, B. K. Kleinschmidt-Demasters, S. Hutter, D. T. Jones, N. Kagawa, R. Hirayama, N. Kijima, Y. Chiba, M. Kinoshita, K. Takano, D. Eino, S. Fukuya, F. Yamamoto, K. Nakanishi, N. Hashimoto, Y. Hashii, J. Hara, T. Yoshimine, J. Wang, C. Guo, Q. Yang, Z. Chen, I. Filipek, E. Swieszkowska, M. Tarasinska, D. Perek, R. Kebudi, B. Koc, O. Gorgun, F. Y. Agaoglu, J. Wolff, E. Darendeliler, K. Kerl, J. Gronych, J. McGlade, R. Endersby, H. Hii, T. Johns, J. Sastry, D. Murphy, M. Ronghe, C. Cunningham, F. Cowie, R. Jones, A. Calisto, M. Sangra, C. Mathieson, J. Brown, K. Phuakpet, V. Larouche, U. Bartels, T. Ishida, D. Hasegawa, K. Miyata, S. Ochi, A. Saito, A. Kozaki, T. Yanai, K. Kawasaki, K. Yamamoto, A. Kawamura, T. Nagashima, Y. Akasaka, T. Soejima, M. Yoshida, Y. Kosaka, A. von Bueren, T. Goschzik, R. Kortmann, K. von Hoff, C. Friedrich, A. z. Muehlen, M. Warmuth-Metz, N. Soerensen, F. Deinlein, I. Zwiener, A. Faldum, J. Kuehl, K. KRAMER, N. P. -Taskar, P. Zanzonico, J. L. Humm, S. L. Wolden, N.-K. V. Cheung, S. Venkataraman, I. Alimova, P. Harris, D. Birks, I. Balakrishnan, A. Griesinger, N. K. Foreman, R. Vibhakar, A. Margol, N. Robison, J. Gnanachandran, L. Hung, R. Kennedy, M. Vali, G. Dhall, J. Finlay, A. Erdrich-Epstein, M. Krieger, R. Drissi, M. Fouladi, F. Gilles, A. Judkins, R. Sposto, S. Asgharzadeh, A. Peyrl, M. Chocholous, S. Holm, P. Grillner, K. Blomgren, A. Azizi, T. Czech, B. Gustafsson, K. Dieckmann, U. Leiss, I. Slavc, S. Babelyan, I. Dolgopolov, R. Pimenov, G. Mentkevich, S. Gorelishev, M. Laskov, A. O. von Bueren, J. Nowak, R. D. Kortmann, M. Mynarek, K. Muller, N. U. Gerber, H. Ottensmeier, R. Kwiecien, M. Yankelevich, V. Boyarshinov, I. Glekov, S. Ozerov, S. Gorelyshev, A. Popa, N. Subbotina, A. M. Martin, C. Nirschl, M. Polanczyk, R. Bell, D. Martinez, L. M. Sullivan, M. Santi, P. C. Burger, J. M. Taube, C. G. Drake, D. M. Pardoll, M. Lim, L. Li, W.-G. Wang, J.-X. Pu, H.-D. Sun, R. Ruggieri, M. H. Symons, M. I. Vanan, S. Bolin, S. Schumacher, R. Zeid, F. Yu, N. Vue, W. Gibson, B. Paolella, F. J. Swartling, M. W. Kieran, J. E. Bradner, O. Maher, S. Khatua, N. Tarek, W. Zaky, T. Gupta, S. Mohanty, S. Kannan, R. Jalali, E. Kapitza, D. Denkhaus, A. z. Muhlen, D. G. van Vuurden, M. Garami, J. Fangusaro, T. B. Davidson, M. J. G. da Costa, J. Sterba, S. C. Clifford, J. L. Finlay, R. Schmidt, J. Felsberg, H. Skladny, F. Cremer, G. Reifenberger, R. Kunder, E. Sridhar, A. A. Moiyadi, A. Goel, N. Goel, N. Shirsat, R. Othman, L. Storer, I. Kerr, B. Coyle, N. Law, M. L. Smith, M. Greenberg, S. Laughlin, D. Malkin, F. Liu, I. Moxon-Emre, N. Scantlebury, A. Nasir, D. Onion, A. Lourdusamy, A. Grabowska, Y. Cai, T. Bradshaw, R. S. S. de Medeiros, A. Beaugrand, S. Soares, S. Epelman, W. Wang, M. Sultan, R. J. Wechsler-Reya, M. Zapatka, B. Radlwimmer, D. Alderete, L. Baroni, F. Lubinieki, F. Auad, M. L. Gonzalez, W. Puya, P. Pacheco, O. Aurtenetxe, A. Gaffar, L. Gros, O. Cruz, C. Calvo, N. Shinojima, H. Nakamura, J.-i. Kuratsu, A. Hanaford, C. Eberhart, T. Archer, P. Tamayo, S. Pomeroy, E. Raabe, K. De Braganca, S. Gilheeney, Y. Khakoo, K. Kramer, S. Wolden, I. Dunkel, R. R. Lulla, J. Laskowski, S. Goldman, V. Gopalakrishnan, D. Shih, X. Wang, C. Faria, C. Raybaud, U. Tabori, J. Rutka, S. Jacobs, F. De Vathaire, I. Diallo, D. Llanas, C. Verez, F. Diop, A. Kahlouche, S. Puget, E. Thompson, E. Prince, V. Amani, P. Sin-Chan, M. Lu, C. Kleinman, T. Spence, D. Picard, K. C. Ho, J. Chan, J. Majewski, N. Jabado, P. Dirks, A. Huang, J. R. Madden, A. M. Donson, D. M. Mirsky, A. Dubuc, S. Mack, D. Gendoo, B. Luu, T. MacDonald, T. Van Meter, S. Croul, A. Laureano, W. Brugmann, C. Denman, H. Singh, H. Huls, J. Moyes, D. Sandberg, L. Silla, L. Cooper, and D. Lee

Subjects
Oncology, Abstracts, Cancer Research, medicine.medical_specialty, Cns pnet, business.industry, Internal medicine, Meta-analysis, medicine, Neurology (clinical), business
Published
2014
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4. Optimal capacitors on-line operation on distribution networks by an integrated control system based on local neurocontrollers

Author

G. Morana, I. Arces, and M. G. Ippolito

Subjects
Engineering, Artificial neural network, business.industry, Local area network, Energy Engineering and Power Technology, Control engineering, Switched capacitor, Optimal control, law.invention, Compensation (engineering), Capacitor, Control theory, law, Control system, Electrical network, Electrical and Electronic Engineering, business
Abstract

This work proposes a contribution to the problem of an optimal control of switched capacitor banks installed in radial distribution networks, by studying the possibility of adopting an integrated control strategy based on the use of neural local controllers able to manage the status of every compensation bank. In order to analyse the feasibility of this solution, the kind of control proposed was implemented in a particular study case, which allowed to compare the performance of a set of local neurocontrollers with the results of a centralized optimisation procedure, for different conditions of load and network configuration.

Published
2002
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5. Management optimization of non small cell lung cancer (NSCLC) specimens. A single institution experience with a multiplexed mass spectrometry approach

Author

N. Bergamin, Stefano Pizzolitto, S. Ciani, G. De Maglio, G. Morana, M. Cattaneo, Emilio Lugatti, S. Distefano, E. De Carlo, E. Poletto, Alessandro Follador, Giacomo Pelizzari, P. Vailati, A. De Pellegrin, and Gianpiero Fasola

Subjects
Oncology, medicine.medical_specialty, business.industry, Internal medicine, medicine, non-small cell lung cancer (NSCLC), Hematology, Single institution, business, Mass spectrometry, medicine.disease
Published
2016
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6. Fault decoupling device: a new device to reduce the impact of distributed generation on electrical distribution systems

Author

G. Morana, G. Cocchiara, Mariano Giuseppe Ippolito, and A. Campoccia

Subjects
Distribution system, Electric power system, Engineering, Power system simulation, business.industry, Asynchronous communication, Distributed generation, Electrical engineering, Electronic engineering, New device, business, Decoupling (electronics), Fault indicator
Abstract

Distributed generation will play an increasing role in the electric power system of the near future. The high penetration of DG in the next years represents a potential resource for the electric power system. On the other hand it brings about several problems concerning with distribution system planning, control and management. The aim of this paper is to analyze some operating conflicts due to the presence of synchronous and asynchronous generators directly connected to distribution networks. The work also proposes a possible solution, based on a new device defined as fault decoupling device (FDD). The principle of operation of this device has been presented and the capability has been proved by means of computer simulations.

Published
2004
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7. Avoiding obstacles by using a proximity US/IR sensitive skin

Author

Paolo Dario, G. Morana, Eugenio Guglielmelli, and V. Genovese

Subjects
Modularity (networks), Engineering, business.industry, Proximity sensor, Obstacle avoidance, Robot, Mobile robot, Computer vision, Motion planning, Artificial intelligence, Sensor fusion, business, Robot control
Abstract

The problem of developing a sensing system for robots moving in a partially or completely unknown environment is investigated. A model of a generalized sensitive skin based on different types of sensors to be located on the whole surface of a robot is illustrated. A logic and hardware structure of the low-level layer of the skin is proposed to guarantee modularity and consistency of sensory data. A configuration including ultrasonic and infrared proximity sensors was chosen for the implementation of a prototype of the skin. A possible physical layout for obtaining a conformable skin to be used on any kind of robot surface is also presented. Local and general rules for low-level sensory data fusion are defined, and possible improvements of real-time obstacle avoidance path planning strategies are discussed by introducing sensor-based instinctive behaviors. A simulation of a modified potential field-based real-time planner for a mobile robot operating in a partially unknown environments is discussed to demonstrate the feasibility of this approach.

Published
2002
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8. Imaging of cholangiocarcinoma

Author

G. Morana and A. Dorigo

Subjects
medicine.medical_specialty, Oncology, Radiological and Ultrasound Technology, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Radiology, business
Published
2011
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9. Distribution power quality improvements using dc links with battery storage in existing networks

Author

L. Russo, P. Pelacchi, M. Ceraolo, and G. Morana

Subjects
Battery (electricity), Engineering, business.industry, Electrical engineering, Distribution transformer, law.invention, Power (physics), Electric utility, Reliability (semiconductor), law, Electromagnetic coil, Electrical network, business, Voltage
Abstract

The use of DC links with battery storage in LV distribution networks provides several advantages for both the final user and the electric utility. In particular, with the use of DC links between the LV windings of the distribution transformers and the load, the following advantages can be obtained: improvement of the power quality of the energy supplied to the user, in particular because the DC link with battery storage can eliminate short voltage interruptions and dips of up to a few minutes; and possibility of using a higher voltage level for the DC line than those presently used for AC lines, thus increasing the link power carrying capability. These features are very important in urban areas, where the installation of new power cables is costly (and sometimes very difficult to realise) and the request for power quality is ever increasing due to the growth in the number of electronic appliances. In this paper, several possible alternatives for realising such a DC link are presented and their feasibility is shown, both in terms of normal and faulty operation and of reliability. Some economic considerations are also dealt with, with particular attention given to a case study. (5 pages)

Published
1997
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10. Difficult liver lesions in patients with cancer

Author

G. Morana and C. Cugini

Subjects
medicine.medical_specialty, Oncology, Radiological and Ultrasound Technology, business.industry, medicine, Cancer, Radiology, Nuclear Medicine and imaging, In patient, General Medicine, Radiology, medicine.disease, business
Published
2011
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11. Psychological evaluation and follow-up in liver transplantation

Author

Josephine G Morana

Subjects
medicine.medical_specialty, Pharmacological therapy, medicine.medical_treatment, Liver transplantation, Personality Assessment, medicine.disease_cause, Cognition, medicine, Humans, Psychological stress, Psychological testing, Topic Highlights, Psychiatry, Intensive care medicine, business.industry, Contraindications, Patient Selection, Gastroenterology, Follow up studies, General Medicine, Liver Transplantation, Psychological evaluation, Transplantation, surgical procedures, operative, Personality Assessment Inventory, business, Stress, Psychological, Follow-Up Studies
Abstract

An increasingly number of transplant centers have integrated a psychological assessment within their protocol for evaluation of patients being considered for transplantation. This paper highlights the psychological criteria for inclusion or exclusion for listing, briefly discusses the psychological dynamics of patients, and addresses possible psychotherapy and pharmacological therapy, before and after transplant.

Published
2009
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12. Abstracts of papers Rational use of drugs

Author

M. N. G. Dukes, Robert M. Elenbaas, G. Tognoni, Dorothy L. Smith, Inga Lunde, H. G. M. Leufkens, Y. A. Hekster, A. Bakker, G. Ostino, H. Petri, F. Sturmans, H. D. Banta, F. F. H. Rutten, L. L. Martens, P. R. Noyce, F. W. H. M. Merkus, Lolkje de Jong-v.d.Berg, Flora Haaijer-Ruskamp, Graham Dukes, B. -M. Vidgren, S. Vidgren, N. Martini, M. L. Sala, G. Scroccaro, P. Olivencia, D. C. McLcod, W. G. Coln, A. G. Hartzcma, C. F. Thaver, J. M. Rodriguez-Sasiain, B. Sangroniz, M. D. Mauleon, M. A. Wood, M. J. Martinez, O. Leinebø, J. N. Saugen, P. Marini, R. Olivato, C. Alberola, E. Cruz-Martos, T. Cruz, N. Marfagon, A. Herreros de Tejada, P. Denig, F. M. Haaijer-Ruskamp, H. Wesseling, A. Versluis, M. P. Gascón, Robert Horne, Jane Hough, N. S. Klazinga, J. J. -E. van Everdingen, P. J. van den Broek, D. K. Roberts, G. B. A. Veitch, K. K. C. Tan, D. A. Holland, M. C. Allwood, A. Nicholls, A. Astobieta, R. Calvo, J. M. Rodriquez-Sasiain, D. Barriquand, C. Pochon, G. Aulagner, A. Vial, C. Dumarest, P. H. Maire, R. W. Jelliffe, J. R. B. J. Brouwers, K. Cramer, J. Gulyas, H. J. vd Kam, J. Sijtsma, C. Donadio, G. Tramonti, G. Garcea, M. Costagli, A. Lucchetti, R. Giordani, G. Paizis, R. Pierotti, G. Falcone, C. Bianchi, C. Gallastegui, R. Farré, I. Jiménez, M. A. Mangues, E. Guasch, G. Ginovart, X. Sagrera, F. Raspall, J. M. Queralto, J. M. Kovarik, C. M. A. Rademaker, J. Verhoef, L. Silvestri, M. Caputo, M. Andrew, E. -L. Toverud, I. Jimenez, I. Castro, E. Alvarez, J. Altimiras, J. J. J. P. M. van de Leur, N. F. Muller, J. M. Van Turnhout, L. Mendizabal, J. M. Rodriguez Sasiain, G. Morana, K. Moss Ofstad, A. -M. Timenes, J. K. F. Vroom, L. T. W. de Jong-van den Berg, P. B. van den Berg, J. J. de Gier, J. Ferres, O. Recoder, Rio T. Sanchez, M. P. Garcia, A. Julia, A. Balet, R. Farre, M. A. Manques, T. Berod, E. Dufay, C. Naveau, M. Combe, A. Sauvageon, Erik Wind Hansen, Jens Dencker Christensen, L. Lie-A-Huen, J. H. Kinqma, D. K. P. Meijer, F. Le Meur, P. Isoard, M. S. Salek, A. Y. Finlay, G. K. Khan, D. K. Luscombe, A. Stuurman, M. P. Boidin, K. Wallenius, R. Ojala, A. Kariluoto, M. Ikonen, A. H. P. Paes, A. Th. G. Blom, S. Wallenius, H. Enlund, K. Vainio, C. Codina, M. Roca, P. Sardà, N. Corominas, J. Massó, J. Ribas, K. Kentra, M. Myllyntausta, M. Saarenpää, M. S. A. Airaksinen, L. Mendarte, A. Rimola, R. Meisters, Y. Hekster, W. Janssen, A. Cox, R. Kempen, S. J. A. Aerdts, R. van Dalen, H. A. L. Clasener, J. Festen, PP Schjphorst, HB Benraad, P. van Asten, R. de Wit, R. J. G. Limbeek, H. G. M. Nagel, R. H. B. Mgyboom, B. H. C. Stricker, B. A. M. van den Berg, T. H. A. Nelen, T. A. G. Tijssen, P. Wassink, M. J. E. Wassink-L'Ortije, P. Gascón, C. Selva, T. Bassons, C. Pardo, M. P. Mas, M. Saqalés, F. Sánchez, V. Mercade, R. Pujol, C. Agustí, M. Cano, T. Gurrera, M. Gorchs, X. Fabregas, L. L. Murgui, A. Verdaguer, W. P. J. Witjes, E. J. Vollaard, B. J. P. Crul, C. Limpens, K. Ahonen, T. Klaukka, I. Vohlonen, J. Martikainen, Daniel Goldenberg, Andres Brodsky, Ines Aparici, Cecilia Argeri, D. Goldenberg, C. Saidman, L. Sevinski, N. Allevato, B. Mujico, J. Ubogui, P. Dorfman, Lupo L. Rodriguez, M. Varela, J. Higa, Annie Fourrier, Philippe Larrouturou, Claire Samarran, Jacqueline Huchet, N. D. Barber, N. Party, P. Wilson, Grethe Eide, Kari Horvei, Angelika Kruse-Jensen, Ingrid Wold, Turid Møark, C. W. Barrett, A. C. Tugwell, B. Søndergaard, M. Rasmussen, F. Davidsen, H. Hey, L. Kierkeby, L. Riis, M. Korhonen, P. Vidgren, T. Ojanen, M. Vidqren, J. Ferrés, T. Sanchez, C. Gallastequi, A. Julià, R. M. C. Herings, B. H. Ch. Stricker, A. J. H. H. Janssen, Heike Dinter, A. J. H. M. Janssen, X. Barbaut, S. Proust, G. Amlagner, F. A. L. M. Eskens, E. Arnoldussen, E. Sieradzki, E. Wanat-Słupska, M. Zlółkowska, I. Pankowska, R. Mazur, B. Ksiazkiewicz, A. Jankowski, A. Marzec, C. Marzec, M. O. Marzec, J. P. Marzec, D. R. Mungall, Lynne Portnoy, F. Lucas, F. Kadir, A. Pijpers, A. Vulto, J. Zuidema, P. Sutton, Antal Samu, John E. Murphy, Ronnie Chapman, Nicolien Wieringa, J. Rolloos, M. T. P. J. Voesten, P. J. J. de Meijer, G. H. P. de Koning, S. Salek, E. Reerink, L. Farrow, G. Raskob, D. Rosenbloom, R. Hull, A. Torras, O. Recorder, C. Torras, J. Cubellsl, M. Font, R. Madridejos, A. Catalán, M. Huguet, N. Franquesa, J. Gratacós, M. Martinez, A. Saltó, E. van der Kleijn, R. J. M. ter Wee, N. Holmberg, and R. F. Brenninkmeijer

Subjects
Pharmacology, Medical education, business.industry, Pharmacology (medical), Pharmacy, business, Psychology, Rational use
Published
1989
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13. 43 Lung-MRI for monitoring cystic fibrosis (CF) patients with pulmonary exacerbation

Author

S. Bertolo, Mirco Ros, V. Tavano, F. De Leo, P. Ciet, and G. Morana

Subjects
Pulmonary and Respiratory Medicine, Lung, business.industry, Statistical difference, Mean age, medicine.disease, Cystic fibrosis, Catheter, medicine.anatomical_structure, Pediatrics, Perinatology and Child Health, Healthy volunteers, medicine, Pediatrics, Perinatology, and Child Health, business, Nuclear medicine, Perfusion, Pulmonary exacerbation
Abstract

NPD is a valuable diagnostic tool in case of questionable CF. Currently, 2 methods, that are considered equivalent, are used: (A) the Calomel/agar method using a needle as subcutaneous reference electrode (RE) and (B) the AgCl/ECG cream method using AgCl electrodes and ECG cream on abraded skin as RE. NPD is measured with a Marquat® catheter under the inferior turbinate (IT). Aim: To compare the subjects’ acceptance for the 2 methods. Methods: CF patients and healthy volunteers (HV) had method A and B in 2 nostrils on separate days. After each test they completed the questionnaire (Q): Did you experience pain at the RE site, at the IT site, during perfusion? Was the procedure annoying? Would you be prepared to repeat NPD? Which method do you prefer? Results: 50 Qs were completed by 12 CF patients (mean age 26.6 y) and 14 HV (mean age 24.7 y). 16/50 (10A/6B, 3CF/13HV) reported pain at RE site, 7/50 (4A/3B, 3CF/4HV) at IT site, and 1/50 (A, HV) during nasal perfusion. 12/50 (9A/3B, 8CF/4HV) found the procedure annoying. 37/50 would agree to repeat NPD, 13/50 probably would. 9/24 subjects (3CF/6HV) preferred method A, 5/24 (2CF/3HV) method B and 10/24 (5CF/5HV) had no preference. 2nd testing (B) was refused twice (2CF) for reasons not related to the test. CF patients reported less pain at RE site compared to HV (p = 0.017). No other statistical difference was found between both tests or between subject groups. Discussion: Overall, NPD was well tolerated. CF patients reported less pain at RE site compared to HV. Both methods were equally accepted by the study subjects. Further analyses of the quality of the tracings is needed to decide which method is most accurate.

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14. Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines

Author

M.A. Bali, Dominik Weishaupt, Jaap Stoker, Jeroen A. W. Tielbeek, Shaji Sebastian, Daniel C. Baumgart, Andrea Laghi, Gerhard Rogler, Yoram Bouhnik, Doug Pendse, Giovanni Morana, Fernando Magro, Livia Biancone, D. Tolan, Davide Bellini, Jordi Rimola, J. Martín-Comín, Stuart A. Taylor, Francesca Maccioni, Steve Halligan, B. Marincek, Torsten Kucharzik, Walter Reinisch, Roberto Grassi, B. Wiarda, Fabiana Castiglione, Alberto Signore, A. Ba-Ssalamah, Silvio Danese, G. Van Assche, Giovanni Maconi, Laurent Peyrin-Biroulet, Julián Panés, Robert Ehehalt, Celso Matos, Sandro Ardizzone, Panes, J, Bouhnik, Y, Reinisch, W, Stoker, J, Taylor, Sa, Baumgart, Dc, Danese, S, Halligan, S, Marincek, B, Matos, C, Peyrin Biroulet, L, Rimola, J, Rogler, G, van Assche, G, Ardizzone, S, Ba Ssalamah, A, Bali, Ma, Bellini, D, Biancone, L, Castiglione, F, Ehehalt, R, Grassi, Roberto, Kucharzik, T, Maccioni, F, Maconi, G, Magro, F, Martín Comín, J, Morana, G, Pendsé, D, Sebastian, S, Signore, A, Tolan, D, Tielbeek, Ja, Weishaupt, D, Wiarda, B, Laghi, A., AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, Radiology and Nuclear Medicine, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Clínica Universitaria, CIBER-EHD, Service de Gastroentérologie [Hôpital Beaujon], Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Department Internal Medicine III [Medizinische Universität Wien], Medizinische Universität Wien = Medical University of Vienna, Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), University of Amsterdam [Amsterdam] (UvA), University College London Hospitals (UCLH), Charité Campus Virchow-Klinikum (CVK), Department of Gastroenterology [Humanitas Research Hospital], Humanitas Research Hospital, University Hospitals Case Medical Center (CLEVELAND - UHCMC), University Hospitals Case Medical Center, Hôpital Erasme [Bruxelles] (ULB), Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Service d'Hépato-gastro-entérologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Vall d'Hebron University Hospital [Barcelona], Division of Gastroenterology and Hepatology [Zurich], Universität Zürich [Zürich] = University of Zurich (UZH)-University hospital of Zurich [Zurich], Mt. Sinai Hospital [Toronto, Canada], University Hospital L. Sacco (ICPS), Department of Radiology [Medizinische Universität Wien], Department of Radiological Oncologic and Pathologic Sciences, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Department of Internal Medicine, Università degli Studi di Roma Tor Vergata [Roma], Università degli studi di Napoli Federico II, Heidelberg University Hospital [Heidelberg], Seconda Università degli studi di Napoli, Städtisches Klinikum Lüneburg, Hospital de São João [Porto], Hospital Universitari de Bellvitge, Hospitalet de Llobregat, Hospital of Treviso, Castle Hill Hospital, Hull & East Yorkshire Hospitals NHS Trust, Nuclear Medicine Unit [Sapienza Roma], Leeds General Infirmary (LGI), Leeds Teaching Hospitals NHS Trust, Stadtspital Triemli Zürich, Medical Center Alkmaar, Peyrin-Biroulet, L, Ba-Ssalamah, A, Grassi, R, Martin-Comin, J, Pendse, D, Laghi, A, J., Pane, Y., Bouhnik, W., Reinisch, J., Stoker, S. A., Taylor, D. C., Baumgart, S., Danese, S., Halligan, B., Marincek, C., Mato, L., Peyrin Biroulet, J., Rimola, G., Rogler, G. v., Assche, S., Ardizzone, A., Ba Ssalamah, M. A., Bali, D., Bellini, L., Biancone, Castiglione, Fabiana, R., Ehehalt, R., Grassi, T., Kucharzik, F., Maccioni, G., Maconi, F., Magro, J., Martín Comín, G., Morana, D., Pendsé, S., Sebastian, A., Signore, D., Tolan, J. A., Tielbeek, D., Weishaupt, B., Wiarda, and A., Laghi

Subjects
Diagnostic Imaging, medicine.medical_specialty, Consensus, Evidence-based practice, [SDV]Life Sciences [q-bio], Consensus, Diagnostic Imaging, MEDLINE, diagnosis/pathology, 030218 nuclear medicine & medical imaging, Primary sclerosing cholangitis, 03 medical and health sciences, Magnetic resonance imaging, 0302 clinical medicine, medicine, Medical imaging, Humans, Intensive care medicine, Computed tomography, Ultrasonography, Settore MED/12 - Gastroenterologia, Crohn's disease, Magnetic resonance cholangiopancreatography, Evidence-Based Medicine, medicine.diagnostic_test, business.industry, Gastroenterology, Ulcerative colitis, Europe, Inflammatory Bowel Diseases, General Medicine, Evidence-based medicine, medicine.disease, 3. Good health, standards, Europe, Evidence-Based Medicine, Humans, Inflammatory Bowel Disease, 030211 gastroenterology & hepatology, Radiology, business
Abstract

International audience; The management of patients with IBD requires evaluation with objective tools, both at the time of diagnosis and throughout the course of the disease, to determine the location, extension, activity and severity of inflammatory lesions, as well as, the potential existence of complications. Whereas endoscopy is a well-established and uniformly performed diagnostic examination, the implementation of radiologic techniques for assessment of IBD is still heterogeneous; variations in technical aspects and the degrees of experience and preferences exist across countries in Europe. ECCO and ESGAR scientific societies jointly elaborated a consensus to establish standards for imaging in IBD using magnetic resonance imaging, computed tomography, ultrasonography, and including also other radiologic procedures such as conventional radiology or nuclear medicine examinations for different clinical situations that include general principles, upper GI tract, colon and rectum, perineum, liver and biliary tract, emergency situation, and the postoperative setting. The statements and general recommendations of this consensus are based on the highest level of evidence available, but significant gaps remain in certain areas such as the comparison of diagnostic accuracy between different techniques, the value for therapeutic monitoring, and the prognostic implications of particular findings.

Published
2013
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