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16 results on '"E Antypa"'

1. A four-probiotic preparation for ventilator-associated pneumonia in multi-trauma patients: results of a randomized clinical trial

Author

Vasilis Grosomanidis, George Stavrou, Maria Tsilika, Giannoula Thoma, Helen Massa, Giakoumis Mitos, Helen Mouloudi, A Voudouris, Niki Paraforou, Petra Malliou, Kyriaki Pagdatoglou, Kyriakos Fotiadis, Georgia Tsaousi, Ntina Kontopoulou, Spyridoula Vasiliagou, Evangelos J. Giamarellos-Bourboulis, E Antypa, Zoi Aidoni, Katerina Kotzampassi, Eleni Gkeka, Georgia Vasiliadou, Angeliki Chorti, and Eleni Antoniadou

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, medicine.medical_treatment, Enteral administration, law.invention, Sepsis, Bifidobacterium animalis, law, Internal medicine, medicine, Humans, Pharmacology (medical), Mechanical ventilation, Greece, biology, business.industry, Probiotics, Ventilator-associated pneumonia, Pneumonia, Ventilator-Associated, General Medicine, Antibiotic Prophylaxis, Middle Aged, medicine.disease, biology.organism_classification, Intensive care unit, Lactobacillus acidophilus, Saccharomyces boulardii, Regimen, Pneumonia, Infectious Diseases, Female, business, Lactobacillus plantarum
Abstract

The role of probiotics in the prevention of ventilator-associated pneumonia (VAP) remains inconclusive. The aim of this study was to assess the efficacy of a probiotic regimen for VAP prophylaxis in mechanically ventilated multi-trauma patients, intubated immediately after the injurious insult. In a randomized, placebo-controlled study enrolling multi-trauma patients, patients expected to require mechanical ventilation for >10 days were assigned at random to receive prophylaxis with a probiotic formula (n=59) or placebo (n=53). The probiotic formula was a preparation of Lactobacillus acidophilus LA-5 [1.75 × 109 colony-forming units (cfu)], Lactobacillus plantarum (0.5 × 109 cfu), Bifidobacterium lactis BB-12 (1.75 × 109 cfu) and Saccharomyces boulardii (1.5 × 109 cfu) in sachets. Each patient received two sachets twice daily for 15 days: one through the nasogastric tube and one spread on the oropharynx. The incidence of VAP was the primary endpoint. The incidence of other infections and sepsis, and the duration of hospital stay were the secondary endpoints. Administration of probiotics reduced the incidence of VAP [11.9% vs 28.3%, hazard ratio (HR) 0.34, 95% confidence interval (CI) 0.13–0.92; P=0.034] and sepsis [6.8% vs 24.5%, odds ratio 0.22, 95% CI 0.07–0.74: P=0.016]. Furthermore, probiotic prophylaxis reduced the time of stay in the intensive care unit (ICU) and the length of hospital stay. The prophylactic use of probiotics with a combination of enteral and topical application to the oropharynx had a positive effect on the incidence of VAP and sepsis, as well as on ICU and total hospital stay in patients receiving protracted mechanical ventilation.

Published
2022
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2. Human Albumin Infusion for Volume Resuscitation: Recommended and Controversial Uses

Author

Eleftheria Chassou, Afroditi K Boutou, Anestis Bekridelis, N. Voloudakis, E Antypa, Eleni Antoniadou, and Spyridon Kapoulas

Subjects
Resuscitation, medicine.medical_specialty, business.industry, medicine.medical_treatment, Vascular surgery, medicine.disease, Endocrine surgery, Sepsis, Anesthesia, Ascites, medicine, Post-anesthesia care unit, medicine.symptom, Volume expander, Intensive care medicine, business, Trauma surgery
Abstract

Human albumin HA is currently the most expensive substitute for blood plasma and has been used since as part of volume expansion and resuscitation HA preparations are administered as volume expander in numerous pathologic conditions such as in the management of ascites and its complications in cirrhotic patients in therapeutic plasma exchange during major operations and in patients with burns trauma critical illness or sepsis However literature data indicate that HA use is rather empirical than evidence based The current review aims to summarize the published literature enlightening the circumstances where HA infusion can be recommended as an appropriate volume expander and indicating the pathologic conditions where its administration is yet controversial

Published
2016
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3. Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

Author

null Author et al, R. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. Ellis, J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez Gallego, F. Esen, G. Orhun, P. Ergin Ozcan, E. Senturk, C. Ugur Yilmaz, N. Orhan, N. Arican, M. Kaya, M. Kucukerden, M. Giris, U. Akcan, S. Bilgic Gazioglu, E. Tuzun, R. Riff, O. Naamani, A. Douvdevani, R. Takegawa, H. Yoshida, T. Hirose, N. Yamamoto, H. Hagiya, M. Ojima, Y. Akeda, O. Tasaki, K. Tomono, T. Shimazu, S. Ono, T. Kubo, S. Suda, T. Ueno, T. Ikeda, H. Ogura, H. Takahashi, J. Kang, Y. Nakamura, T. Kojima, Y. Izutani, T. Taniguchi, M. O, C. Dinter, J. Lotz, B. Eilers, C. Wissmann, R. Lott, M. M. Meili, P. S. Schuetz, H. Hawa, M. Sharshir, M. Aburageila, N. Salahuddin, V. Chantziara, S. Georgiou, A. Tsimogianni, P. Alexandropoulos, A. Vassi, F. Lagiou, M. Valta, G. Micha, E. Chinou, G. Michaloudis, A. Kodaira, H. Imaizumi, M. V. De la Torre-Prados, A. Garcia-De la Torre, A. Enguix-Armada, A. Puerto-Morlan, V. Perez-Valero, A. Garcia-Alcantara, N. Bolton, J. Dudziak, S. Bonney, A. Tridente, P. Nee, G. Nicolaes, M. Wiewel, M. Schultz, K. Wildhagen, J. Horn, R. Schrijver, T. Van der Poll, C. Reutelingsperger, S. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. Evans, E. G. Gayat, J. Struck, A. Cariou, N. Deye, B. Guidet, S. Jabert, J. Launay, M. Legrand, M. Léone, M. Resche-Rigon, E. Vicaut, A. Vieillard-Baron, A. Mebazaa, R. Arnold, M. Capan, A. Linder, P. Akesson, M. Popescu, D. Tomescu, C. L. Sprung, R. Calderon Morales, G. Munteanu, E. Orenbuch-Harroch, P. Levin, H. Kasdan, A. Reiter, T. Volker, Y. Himmel, Y. Cohen, J. Meissonnier, L. Girard, F. Rebeaud, I. Herrmann, B. Delwarde, E. Peronnet, E. Cerrato, F. Venet, A. Lepape, T. Rimmelé, G. Monneret, J. Textoris, N. Beloborodova, V. Moroz, A. Osipov, A. Bedova, Y. Sarshor, A. Pautova, A. Sergeev, E. Chernevskaya, J. Odermatt, R. Bolliger, L. Hersberger, M. Ottiger, M. Christ-Crain, B. Mueller, P. Schuetz, N. K. Sharma, A. K. Tashima, M. K. Brunialti, F. R. Machado, M. Assuncao, O. Rigato, R. Salomao, S. C. Cajander, G. Rasmussen, E. Tina, B. Söderquist, J. Källman, K. Strålin, A. L. Lange, J. S. Sundén-Cullberg, A. M. Magnuson, O. H. Hultgren, P. Van der Geest, M. Mohseni, J. Linssen, R. De Jonge, S. Duran, J. Groeneveld, R. Miller, B. K. Lopansri, L. C. McHugh, A. Seldon, J. P. Burke, J. Johnston, R. Reece-Anthony, A. Bond, A. Molokhia, C. Mcgrath, E. Nsutebu, P. Bank Pedersen, D. Pilsgaard Henriksen, S. Mikkelsen, A. Touborg Lassen, R. Tincu, C. Cobilinschi, Z. Ghiorghiu, R. Macovei, M. A. Wiewel, M. B. Harmon, L. A. Van Vught, B. P. Scicluna, A. J. Hoogendijk, A. H. Zwinderman, O. L. Cremer, M. J. Bonten, M. J. Schultz, N. P. Juffermans, W. J. Wiersinga, G. Eren, Y. Tekdos, M. Dogan, O. Acicbe, E. Kaya, O. Hergunsel, S. Alsolamy, G. Ghamdi, L. Alswaidan, S. Alharbi, F. Alenezi, Y. Arabi, J. Heaton, A. Boyce, L. Nolan, A. Dukoff-Gordon, A. Dean, T. Mann Ben Yehudah, C. Fleischmann, D. Thomas-Rueddel, C. Haas, U. Dennler, K. Reinhart, O. Suntornlohanakul, B. Khwannimit, F. Breckenridge, A. Puxty, P. Szturz, P. Folwarzcny, J. Svancara, R. Kula, P. Sevcik, L. Caneva, A. Casazza, E. Bellazzi, S. Marra, L. Pagani, M. Vetere, R. Vanzino, D. Ciprandi, R. Preda, R. Boschi, L. Carnevale, V. Lopez, M. Aguilar Arzapalo, L. Barradas, A. Escalante, J. Gongora, M. Cetina, B Adamik, D Jakubczyk, A Kübler, A. Radford, T. Lee, J. Singer, J. Boyd, D. Fineberg, M. Williams, J. Russell, E. Scarlatescu, G. Droc, S. Arama, M. Müller, M. Straat, S. S. Zeerleder, C. F. Fuchs, C. S. Scheer, S. W. Wauschkuhn, M. V. Vollmer, K. M. Meissner, S. K. Kuhn, K. H. Hahnenkamp, S. R. Rehberg, M. G. Gründling, S. Hamaguchi, E. Gómez-Sánchez, M. Heredia-Rodríguez, E. Álvarez-Fuente, M. Lorenzo-López, E. Gómez-Pesquera, M. Aragón-Camino, P. Liu-Zhu, A. Sánchez-López, A. Hernández-Lozano, M. T. Peláez-Jareño, E. Tamayo, D. O. Thomas-Rüddel, V. Adora, A. Kar, A. Chakraborty, S. Roy, A. Bandyopadhyay, M. Das, G. BenYehudah, M. Salim, N. Kumar, L. Arabi, T. Burger, P. Lephart, E. Toth-martin, C. Valencia, N. Hammami, S. Blot, J. L. Vincent, M. L. Lambert, J. Brunke, T. Riemann, I. Roschke, S. Nimitvilai, K. Jintanapramote, S. Jarupongprapa, D. Adukauskiene, D. Valanciene, G. Bose, V. Lostarakos, B. Carr, S. Khedher, A. Maaoui, A. Ezzamouri, M. Salem, J. Chen, D. R. Cranendonk, M. Day, G. Penrice, K. Roy, P. Robertson, G. Godbole, B. Jones, M. Booth, L. Donaldson, Y. Kawano, H. Ishikura, H. Al-Dorzi, M. Almutairi, B. Alhamadi, A. Crizaldo Toledo, R. Khan, B. Al Raiy, H. Talaie, J. A. Van Oers, A. Harts, E. Nieuwkoop, P. Vos, Y. Boussarsar, F. Boutouta, S. Kamoun, I. Mezghani, S. Koubaji, A. Ben Souissi, A. Riahi, M. S. Mebazaa, E. Giamarellos-Bourboulis, N. Tziolos, C. Routsi, C. Katsenos, I. Tsangaris, I. Pneumatikos, G. Vlachogiannis, V. Theodorou, A. Prekates, E. Antypa, V. Koulouras, N. Kapravelos, C. Gogos, E. Antoniadou, K. Mandragos, A. Armaganidis, A. R. Robles Caballero, B. Civantos, J. C. Figueira, J. López, A. Silva-Pinto, F. Ceia, A. Sarmento, L. Santos, G. Almekhlafi, Y. Sakr, S. Baharoon, A. Aldawood, A. Matroud, J. Alchin, S. Al Johani, H. Balkhy, S. Y. Yousif, B. O. Alotabi, A. S. Alsaawi, J. Ang, M. D. Curran, D. Enoch, V. Navapurkar, A. Morris, R. Sharvill, J. Astin, J. Patel, C. Kruger, J. O’Neal, H. Rhodes, J. Jancik, B. François, P. F. Laterre, P. Eggimann, A. Torres, M. Sánchez, P. F. Dequin, G. L. Bassi, J. Chastre, H. S. Jafri, M. Ben Romdhane, Z. Douira, M. Bousselmi, A. Vakalos, V. Avramidis, T. H. Craven, G. Wojcik, K. Kefala, J. McCoubrey, J. Reilly, R. Paterson, D. Inverarity, I. Laurenson, T. S. Walsh, S. Mongodi, B. Bouhemad, A. Orlando, A. Stella, G. Via, G. Iotti, A. Braschi, F. Mojoli, M. Haliloglu, B. Bilgili, U. Kasapoglu, I. Sayan, M. Süzer Aslan, A. Yalcin, I. Cinel, H. E. Ellis, K. Bauchmuller, D. Miller, A. Temple, C. E. Luyt, M. Singer, Y. Nassar, M. S. Ayad, A. Trifi, S. Abdellatif, F. Daly, R. Nasri, S. Ben Lakhal, F. Gul, A. Kuzovlev, A. Shabanov, S. Polovnikov, N. Kadrichu, T. Dang, K. Corkery, P. Challoner, G. Li Bassi, E. Aguilera, C. Chiurazzi, C. Travierso, A. Motos, L. Fernandez, R. Amaro, T. Senussi, F. Idone, J. Bobi, M. Rigol, C. J. Hodiamont, J. M. Janssen, C. S. Bouman, R. A. Mathôt, M. D. De Jong, R. M. Van Hest, L. Payne, G. L. Fraser, B. Tudor, M. Lahner, G. Roth, C. Krenn, P. Jault, J. Gabard, T. Leclerc, S. Jennes, Y. Que, A. Rousseau, F. Ravat, A. Eissa, S. Al-Harbi, T. Aldabbagh, S. Abdellatif., F. Paramba, N. Purayil, V. Naushad, O. Mohammad, V. Negi, P. Chandra, A. Kleinsasser, M. R. Witrz, J. F. Buchner-Doeven, A. M. Tuip-de Boer, J. C. Goslings, M. Van Hezel, A Boing, R Van Bruggen, N Juffermans, D. Markopoulou, K. Venetsanou, V. Kaldis, D. Koutete, D. Chroni, I. Alamanos, L. Koch, E. Walter, K. Maekawa, M. Hayakawa, S. Kushimoto, A. Shiraishi, H. Kato, J. Sasaki, T. Matauoka, T. Uejima, N. Morimura, A. Hagiwara, M. Takeda, O. Tarabrin, S. Shcherbakow, D. Gavrychenko, G. Mazurenko, V. Ivanova, O. Chystikov, C. Plourde, J. Lessard, J. Chauny, R. Daoust, L. Kropman, L. In het Panhuis, J. Konings, D. Huskens, E. Schurgers, M. Roest, B. De Laat, M. Lance, M. Durila, P. Lukas, M. Astraverkhava, J. Jonas, I. Budnik, B. Shenkman, H. Hayami, Y. Koide, T. Goto, R. Iqbal, Y. Alhamdi, N. Venugopal, S. Abrams, C. Downey, C. H. Toh, I. D. Welters, V. B. Bombay, J. M. Chauny, R. D. Daoust, J. L. Lessard, M. M. Marquis, J. P. Paquet, K. Siemens, D. Sangaran, B. J. Hunt, A. Durward, A. Nyman, I. A. Murdoch, S. M. Tibby, F. Ampatzidou, D. Moisidou, E. Dalampini, M. Nastou, E. Vasilarou, V. Kalaizi, H. Chatzikostenoglou, G. Drossos, S. Spadaro, A. Fogagnolo, T. Fiore, A. Schiavi, V. Fontana, F. Taccone, C. Volta, E. Chochliourou, E. Volakli, A. Violaki, E. Samkinidou, G. Evlavis, V. Panagiotidou, M. Sdougka, R. Mothukuri, C. Battle, K. Guy, J. Wijesuriya, S. Keogh, A. Docherty, R. O’Donnell, S. Brunskill, M. Trivella, C. Doree, L. Holst, M. Parker, M. Gregersen, J. Almeida, T. Walsh, S. Stanworth, S. Moravcova, J. Mansell, A. Rogers, R. A. Smith, C. Hamilton-Davies, A. Omar, M. Allam, O. Bilala, A. Kindawi, H. Ewila, A. Malamas, G. Ferreira, J. Caldas, J. Fukushima, E. A. Osawa, E. Arita, L. Camara, S. Zeferino, J. Jardim, F. Gaioto, L. Dallan, F. B. Jatene, R. Kalil Filho, F. Galas, L. A. Hajjar, C. Mitaka, T. Ohnuma, T. Murayama, F. Kunimoto, M. Nagashima, T. Takei, M. Tomita, K. Mahmoud, S. Hanoura, S. Sudarsanan, P. Sivadasan, H. Othamn, Y. Shouman, R. Singh, A. Al Khulaifi, I. Mandel, S. Mikheev, I. Suhodolo, V. Kiselev, Y. Svirko, Y. Podoksenov, S. A. Jenkins, R. Griffin, M. S. Tovar Doncel, A. Lima, C. Aldecoa, C. Ince, A. Taha, A. Shafie, M. Mostafa, N. Syed, H. Hon, F. Righetti, E. Colombaroli, G. Castellano, M. Hravnak, L. C. Chen, A. D. Dubrawski, G. C. Clermont, M. R. Pinsky, S. Gonzalez, D. Macias, J. Acosta, P. Jimenez, A. Loza, A. Lesmes, F. Lucena, C. Leon, M. Bastide, J. Richecoeur, E. Frenoy, C. Lemaire, B. Sauneuf, F. Tamion, S. Nseir, D. Du Cheyron, H. Dupont, J. Maizel, M. Shaban, R. Kolko, M. AbuRageila, A. AlHussain, P. Mercado, L. Kontar, D. Titeca, F. Brazier, A. Riviere, M. Joris, T. Soupison, B. De Cagny, M. Slama, J. Wagner, A. Körner, M. Kubik, S. Kluge, D. Reuter, B. Saugel, T. Tran, D. De Bels, A. Cudia, M. Strachinaru, P. Ghottignies, J. Devriendt, C. Pierrakos, Ó. Martínez González, R. Blancas, J. Luján, D. Ballesteros, C. Martínez Díaz, A. Núñez, C. Martín Parra, B. López Matamala, M. Alonso Fernández, M. Chana, W. Huber, M. Eckmann, F. Elkmann, A. Gruber, I. Klein, R. M. Schmid, T. Lahmer, P. W. Moller, S. Sondergaard, S. M. Jakob, J. Takala, D. Berger, D. Bastoni, H. Aya, L. Toscani, L. Pigozzi, A. Rhodes, M. Cecconi, C. Ostrowska, A. Abbas, J. Mellinghoff, C. Ryan, D. Dawson, M. Cronhjort, O. Wall, E. Nyberg, R. Zeng, C. Svensen, J. Mårtensson, E. Joelsson-Alm, N. Parenti, C. Palazzi, L. A. Amidei, F. B. Borrelli, S. C. Campanale, F. T. Tagliazucchi, G. S. Sedoni, D. L. Lucchesi, E. C. Carella, A. L Luciani, M. Mackovic, N. Maric, M. Bakula, R. M. Grounds, N. Fletcher, B. Avard, P. Zhang, M. Mezidi, J. Charbit, M. Ould-Chikh, P. Deras, C. Maury, O. Martinez, X. Capdevila, P. Hou, W. Z. Linde-Zwirble, I. D. Douglas, N. S. Shapiro, Y. Ben Aicha, B. Laribi, B. Jeribi, C. Pereira, R. Marinho, R. Antunes, A. Marinho, M. Crivits, M. Raes, J. Decruyenaere, E. Hoste, V. Bagin, V. Rudnov, A. Savitsky, M. Astafyeva, I. Korobko, V. Vein, T. Kampmeier, P. Arnemann, M. Hessler, A. Wald, K. Bockbreder, A. Morelli, H. Van Aken, S. Rehberg, C. Ertmer, S. Reddy, M. Bailey, R. Beasley, R. Bellomo, D. Mackle, A. Psirides, P. Young, H. Venkatesh, S. Ramachandran, A. Basu, H. Nair, S. Egan, J. Bates, S. Oliveira, N. R. Rangel Neto, F. Q. Reis, C. P. Lee, X. L. Lin, C. Choong, K. M. Eu, W. Y. Sim, K. S. Tee, J. Pau, J. Abisheganaden, K. Maas, H. De Geus, E. Lafuente, J. Moura, T. E. Doris, D. Monkhouse, T. Shipley, S. Kardasz, I Gonzalez, S. Stads, A. J. Groeneveld, I. Elsayed, N. Ward, A. Raithatha, A. Steuber, C. Pelletier, S. Schroeder, E. Michael, T. Slowinski, D. Kindgen-Milles, S. Ghabina, F. Turani, A. Belli, S. Busatti, G. Barettin, F. Candidi, F. Gargano, R. Barchetta, M. Falco, O. Demirkiran, M. Kosuk, S. Bozbay, V. Weber, J. Hartmann, S. Harm, I. Linsberger, T. Eichhorn, G. Valicek, G. Miestinger, C. Hoermann, S. Faenza, D. Ricci, E. Mancini, C. Gemelli, A. Cuoghi, S. Magnani, M. Atti, T. Laddomada, A. Doronzio, B. Balicco, M. C. Gruda, P. O’Sullivan, V. P. Dan, T. Guliashvili, A. Scheirer, T. D. Golobish, V. J. Capponi, P. P. Chan, K. Kogelmann, M. Drüner, D. Jarczak, A. B. Belli, S. M. Martni, V. C. Cotticelli, F. Mounajergi, S. Morimoto, I. Hussain, A. Nadeem, K. Ghorab, K. Maghrabi, S. K. Kloesel, C. Goldfuss, A. Stieglitz, A. S. Stieglitz, L. Krstevska, G. Albuszies, G. Jimmy, J. Izawa, T. Iwami, S. Uchino, M. Takinami, T. Kitamura, T. Kawamura, J. G. Powell-Tuck, S. Crichton, M. Raimundo, L. Camporota, D. Wyncoll, M. Ostermann, A. Hana, H. R. De Geus, M. Aydogdu, N. Boyaci, S. Yuksel, G. Gursel, A. B. Cayci Sivri, J. Meza-Márquez, J. Nava-López, R. Carrillo-Esper, A. Dardashti, A. Grubb, M. Wetzstein, E. Peters, H. Njimi, P. Pickkers, M. Waraich, J. Doyle, T. Samuels, L. Forni, N. Desai, R. Baumber, P. Gunning, A. Sell, S. Lin, H. Torrence, M. O’Dwyer, C. Kirwan, J. Prowle, T. Kim, M. E. O’Connor, R. W. Hewson, C. J. Kirwan, R. M. Pearse, M. Maksoud, O. Uzundere, D. Memis, M. Ýnal, A. Gultekin, N. Turan, M. A. Aydin, H. Basar, I. Sencan, A. Kapuagasi, M. Ozturk, Z. Uzundurukan, D. Gokmen, A. Ozcan, C. Kaymak, V. A. Artemenko, A. Budnyuk, R. Pugh, S. Bhandari, T. Mauri, C. Turrini, T. Langer, P. Taccone, C. A. Volta, C. Marenghi, L. Gattinoni, A. Pesenti, L. Sweeney, A. O’Sullivan, P. Kelly, E. Mukeria, R. MacLoughlin, M. Pfeffer, J. T. Thomas, G. B. Bregman, G. K. Karp, E. K. Kishinevsky, D. S. Stavi, N. A. Adi, T. Poropat, R. Knafelj, E. Llopart, M. Batlle, C. De Haro, J. Mesquida, A. Artigas, D. Pavlovic, L. Lewerentz, A. Spassov, R. Schneider, S. De Smet, S. De Raedt, E. Derom, P Depuydt, S. Oeyen, D. Benoit, A. Gobatto, B. Besen, P. Tierno, L. Melro, P. Mendes, F. Cadamuro, M. Park, L. M. Malbouisson, B. C. Civantos, J. L. Lopez, A. Robles, J. Figueira, S. Yus, A. Garcia, A. Oglinda, G. Ciobanu, C. Oglinda, L. Schirca, T. Sertinean, V. Lupu, M. Wolny, A. Pagano, F. Numis, G. Visone, L. Saldamarco, T. Russo, G. Porta, F. Paladino, C. Bell, J. Liu, J. Debacker, C. Lee, E. Tamberg, V. Campbell, S. Mehta, Ý. Kara, F. Yýldýrým, A. Zerman, Z. Güllü, N. Boyacý, B. Basarýk Aydogan, Ü. Gaygýsýz, K. Gönderen, G. Arýk, M. Turkoglu, G. Aygencel, Z. Ülger, Z. Isýkdogan, Ö. Özdedeoglu, M. Badoglu, U. Gaygýsýz, N. Kongpolprom, C. Sittipunt, A. Eden, Y. Kokhanovsky, S. Bursztein – De Myttenaere, R. Pizov, L. Neilans, N. MacIntyre, M. Radosevich, B. Wanta, T. Meyer, N. Smischney, D. Brown, D. Diedrich, A. Fuller, P. McLindon, K. Sim, M. Shoaeir, K. Noeam, A. Mahrous, R. Matsa, A. Ali, C. Dridi, F. Haddad, A. Pérez-Calatayud, A. Zepeda-Mendoza, M. Diaz-Carrillo, E. Arch-Tirado, S. Carbognin, L. Pelacani, F. Zannoni, A. Agnoli, G. Gagliardi, R. Cho, A. Adams, S. Lunos, S. Ambur, R. Shapiro, M. Prekker, M. Thijssen, L. Janssen, N. Foudraine, C. J. Voscopoulos, J. Freeman, E. George, D. Eversole, S. Muttini, R. Bigi, G. Villani, N. Patroniti, G. Williams, E George, A. Waldmann, S. Böhm, W. Windisch, S. Strassmann, C. Karagiannidis, C. K. Karagiannidis, A. W. Waldmann, S. B. Böhm, W. W. Windisch, P. Persson, S. Lundin, O. Stenqvist, C. S. Serra, A. P. Pagano, M. M. Masarone, L. R. Rinaldi, A. A. Amelia, M. F. Fascione, L. A. Adinolfi, E. R. Ruggiero, F. Asota, K. O’Rourke, S. Ranjan, P. Morgan, J. W. DeBacker, L. O’Neill, L. Munshi, L. Burry, E. Fan, S. Poo, K. Mahendran, J. Fowles, C. Gerrard, A. Vuylsteke, R. Loveridge, C. Chaddock, S. Patel, V. Kakar, C. Willars, T. Hurst, C. Park, T. Best, A. Vercueil, G. Auzinger, A. Borgman, A. G. Proudfoot, E. Grins, K. E. Emiley, J. Schuitema, S. J. Fitch, G. Marco, J. Sturgill, M. G. Dickinson, M. Strueber, A. Khaghani, P. Wilton, S. M. Jovinge, C. Sampson, S. Harris-Fox, M. E. Cove, L. H. Vu, A. Sen, W. J. Federspiel, J. A. Kellum, C. Mazo Torre, J. Riera, S. Ramirez, B. Borgatta, L. Lagunes, J. Rello, A. K. Kuzovlev, A. Goloubev, S. Nenchuk, V. Karavana, C. Glynos, A. Asimakos, K. Pappas, C. Vrettou, M. Magkou, E. Ischaki, G. Stathopoulos, S. Zakynthinos, I. Kozhevnikova, F. Dalla Corte, S. Grasso, P. Casolari, G. Caramori, T. Andrianjafiarinoa, T. Randriamandrato, T. Rajaonera, S. El-Dash, E. L. V. Costa, M. R. Tucci, F Leleu, L Kontar, G. Bacari-Risal, M. Amato, S. El Dash, null Remmington, A. Fischer, S. Squire, M. Boichat, H. Honzawa, H. Yasuda, T. Adati, S. Suzaki, M. Horibe, M. Sasaki, M. Sanui, J. Daniel, H. Miranda, K. Milinis, M. Cooper, G. R. Williams, E. McCarron, S. Simants, I. Patanwala, I. Welters, Y. Su, J. Fernández Villanueva, R. Fernández Garda, A. López Lago, E. Rodríguez Ruíz, R. Hernández Vaquero, S. Tomé Martínez de Rituerto, E. Varo Pérez, N. Lefel, F. Schaap, D. Bergmans, S. Olde Damink, M. Van de Poll, K. Tizard, C. Lister, L. Poole, D. Ringaitiene, D. Gineityte, V. Vicka, I. Norkiene, J. Sipylaite, A. O’Loughlin, V. Maraj, J. Dowling, M. B. Velasco, D. M. Dalcomune, E. B. Dias, S. L. Fernandes, T. Oshima, S. Graf, C. Heidegger, L. Genton, V. Karsegard, Y. Dupertuis, C. Pichard, N. Friedli, Z. Stanga, L. Vandersteen, B. Stessel, S. Evers, A. Van Assche, L. Jamaer, J. Dubois, H. Castro, J. Valente, P. Martins, P. Casteloes, C. Magalhaes, S. Cabral, M. Santos, B. Oliveira, A. Salgueiro, S. Duarte, S. Castro, M. Melo, S. Gray, K. Maipang, R. Bhurayanontachai, L. G. Grädel, P. Schütz, P. Langlois, W. Manzanares, M. Lemieux, G. Elke, F. Bloos, D. Heyland, I. Aramendi, N. Babo, M. Hoshino, Y. Haraguchi, S. Kajiwara, T. Mitsuhashi, T. Tsubata, M. Aida, T. Rattanapraphat, C. Kongkamol, B. Xavier, C. Koutsogiannidis, M. Moschopoulou, G. Taskin, M. Çakir, AK Güler, A. Taskin, N. Öcal, S. Özer, L. Yamanel, J. M. Wong, C. Fitton, S. Anwar, S. Stacey, M. Aggou, B. Fyntanidou, S. Patsatzakis, E. Oloktsidou, K. Lolakos, E. Papapostolou, V. Grosomanidis, S. Gaudry, V. Desailly, P. Pasquier, PB Brun, AT Tesnieres, JD Ricard, D. Dreyfuss, A. Mignon, J. C White, A. Stilwell, G. Friedlaender, M. Peters, S. Stipulante, A. Delfosse, AF Donneau, A. Ghuysen, C. Feldmann, D. Freitag, W. Dersch, M. Irqsusi, D. Eschbach, T. Steinfeldt, H. Wulf, T. Wiesmann, J. Cholkraisuwat, S. Beitland, E. Nakstad, H. Stær-Jensen, T. Drægni, G. Andersen, D. Jacobsen, C. Brunborg, B. Waldum-Grevbo, K. Sunde, K. Hoyland, D. Pandit, K. Hayakawa, K. Kotzampassi, L. Loukipoudi, E. Doumaki, M. M. Admiraal, M. Van Assen, M. J. Van Putten, M. Tjepkema-Cloostermans, A. F. Van Rootselaar, F. Ragusa, A. Marudi, S. Baroni, A. Gaspari, E. Bertellini, T. Abdullah, S. Abdel Monem, S. Alcorn, S. McNeill, S. Russell, W. Eertmans, C. Genbrugge, I. Meex, J. Dens, F. Jans, C. De Deyne, B Avard, R Burns, A. Patarchi, T. Spina, H. Tanaka, N. Otani, S. Ode, S. Ishimatsu, J. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. Shin, M. H. Won, S. Dakova, Z. Ramsheva, K. Ramshev, A Marudi, S Baroni, A Gaspari, E Bertellini, P. E. Ozcan, S. Sencer, C. Ulusoy, M. Fallenius, M. B. Skrifvars, M. Reinikainen, S. Bendel, R. Raj, M. Abu-Habsa, C. Hymers, A. Borowska, H. Sivadhas, S. Sahiba, S. Perkins, J. Rubio, J. A. Rubio, R. Sierra, S. English, M. Chasse, A. Turgeon, F. Lauzier, D. Griesdale, A. Garland, D. Fergusson, R. Zarychanski, A. Tinmouth, C. Van Walraven, K. Montroy, J. Ziegler, R. Dupont Chouinard, R. Carignan, A. Dhaliwal, C. Lum, J. Sinclair, G. Pagliarello, L. McIntyre, T. Groza, N. Moreau, D. Castanares-Zapatero, P. Hantson, M. Carbonara, F. Ortolano, T. Zoerle, S. Magnoni, S. Pifferi, V. Conte, N. Stocchetti, L. Carteron, T. Suys, C. Patet, H. Quintard, M. Oddo, V. Spatenkova, E. Pokorna, P. Suchomel, N. Ebert, T. Bylinski, C. Hawthorne, M. Shaw, I. Piper, J. Kinsella, A. K. Kink, I. R. Rätsep, A. Boutin, L. Moore, J. Lacroix, P. Lessard-Bonaventure, A. F. Turgeon, R. Green, M. Erdogan, M. Butler, P. Desjardins, D. A. Fergusson, B. Goncalves, B. Vidal, C. Valdez, A. C. Rodrigues, L. Miguez, G. Moralez, T. Hong, A. Kutz, P. Hausfater, D. Amin, T. Struja, S. Haubitz, A. Huber, T. Brown, J. Collinson, C. Pritchett, T. Slade, M. Le Guen, S. Hellings, R. Ramsaran, A. Alsheikhly, T. Abe, L. Kanapeckaite, R. Bahl, M. Q. Russell, K. J. Real, R. M. Lyon, N. P. Oveland, J. Penketh, M. Mcdonald, F. Kelly, M. Alfafi, W. Almutairi, B. Alotaibi, A. E Van den Berg, Y. Schriel, L. Dawson, I. A. Meynaar, D. Silva, S. Fernandes, J. Gouveia, J. Santos Silva, J. Foley, A. Kaskovagheorgescu, D. Evoy, J. Cronin, J. Ryan, M. Huck, C. Hoffmann, J. Renner, P. Laitselart, N. Donat, A. Cirodde, J. V. Schaal, Y. Masson, A. Nau, O. Howarth, K. Davenport, P. Jeanrenaud, S. Raftery, P. MacTavish, H. Devine, J. McPeake, M. Daniel, T. Quasim, S. Alrabiee, A. Alrashid, O. Gundogan, C. Bor, E. Akýn Korhan, K. Demirag, M. Uyar, F. Frame, C. Ashton, L. Bergstrom Niska, P. Dilokpattanamongkol, T. Suansanae, C. Suthisisang, S. Morakul, C. Karnjanarachata, V. Tangsujaritvijit, S. Mahmood, H. Al Thani, A. Almenyar, S. E. Morton, Y. S. Chiew, C. Pretty, J. G. Chase, G. M. Shaw, P. Kordis, V. Grover, I. Kuchyn, K. Bielka, Z. Aidoni, G. Stavrou, C. Skourtis, S. D. Lee, K. Williams, I. D. Weltes, S. Berhane, C. Arrowsmith, C. Peters, S. Robert, R. B. Panerai, T. G. Robinson, E. Borg-Seng-Shu, M. De Lima Oliveira, N. C. Mian, R. Nogueira, S. P. Zeferino, M. Jacobsen Teixeira, P. Killeen, M. McPhail, W. Bernal, J. Maggs, J. Wendon, T. Hughes, L. U. Taniguchi, E. M. Siqueira, J. M. Vieira Jr, L. C. Azevedo, A. N. Ahmad, E. Helme, S. Hadfield, J. Shak, C. Senver, R. Howard-Griffin, P. Wacharasint, P. Fuengfoo, N. Sukcharoen, R. Rangsin, D. Sbiti-Rohr, H. Na, S. Song, S. Lee, E. Jeong, K. Lee, E. Zoumpelouli, E. A Volakli, V. Chrysohoidou, K. Charisopoulou, E. Kotzapanagiotou, K. Manavidou, Z. Stathi, B. AlGhamdi, Q. Marashly, K. Zaza, M. Khurshid, Z. Ali, M. Malgapo, M. Jamil, A. Shafquat, M. Shoukri, M. Hijazi, F. A. Rocha, K. Ebecken, L. S. Rabello, M. F. Lima, R. Hatum, F. V. De Marco, A. Alves, J. E. Pinto, M. Godoy, P. E. Brasil, F. A. Bozza, J. I. Salluh, M. Soares, J. Krinsley, G. Kang, J. Perry, H. Hines, K. M. Wilkinson, C. Tordoff, B. Sloan, M. C. Bellamy, E. Moreira, F. Verga, M. Barbato, G. Burghi, M Soares, U. V. Silva, A. P. Torelly, J. M. Kahn, D. C. Angus, M. F. Knibel, R. Marshall, T. Gilpin, D. Mota, B. Loureiro, J. Dias, O. Afonso, F. Coelho, A. Martins, F. Faria, H. Al Orainni, F. AlEid, H. Tlaygeh, A. Itani, A. Hejazi, J. Messika, J. D. Ricard, S. Guillo, B. Pasquet, E. Dubief, F. Tubach, K. James, P. Temblett, L. Davies, C. Lynch, S. Pereira, S. Cavaco, J. Fernandes, I. Moreira, E. Almeida, F. Seabra Pereira, M. Malheiro, F. Cardoso, I. Aragão, T. Cardoso, M. Fister, P. Muraray Govind, N. Brahmananda Reddy, R. Pratheema, E. D. Arul, J. Devachandran, N. Chin-Yee, G. D’Egidio, K. Thavorn, K. Kyeremanteng, A. G. Murchison, K. Swalwell, J. Mandeville, D. Stott, I. Guerreiro, C. Goossens, M. B. Marques, S. Derde, S. Vander Perre, T. Dufour, S. E. Thiessen, F. Güiza, T. Janssens, G. Hermans, I. Vanhorebeek, K. De Bock, G. Van den Berghe, L. Langouche, B. Miles, S. Madden, M. Weiler, P. Marques, C. Rodrigues, M. Boeira, K. Brenner, C. Leães, A. Machado, R. Townsend, J. Andrade, R. Kishore, C. Fenlon, T. Fiks, A. Ruijter, M. Te Raa, P. Spronk, P. Docherty, J. Dickson, E. Moltchanova, C. Scarrot, T. Hall, W. C. Ngu, J. M. Jack, A. Pavli, X. Gee, E. Akin Korhan, M. Shirazy, A. Fayed, S. Gupta, A. Kaushal, S. Dewan, A. Varma, E. Ghosh, L. Yang, L. Eshelman, B. Lord, E. Carlson, R. Broderick, J. Ramos, D. Forte, F. Yang, J. Feeney, K. Wilkinson, K. Shuker, M. Faulds, D. Bryden, L. England, K Shuker, A Tridente, M Faulds, A Matheson, J. Gaynor, D Bryden, S South Yorkshire Hospitals Researc ᅟ, B. Peroni, R. Daglius-Dias, L. Miranda, C. Cohen, C. Carvalho, I. Velasco, J. M. Kelly, A. Neill, G. Rubenfeld, N. Masson, A. Min, E. Boezeman, J. Hofhuis, A. Hovingh, R. De Vries, G. Cabral-Campello, M. Van Mol, M. Nijkamp, E. Kompanje, P. Ostrowski, K. Kiss, B. Köves, V. Csernus, Z. Molnár, Y. Hoydonckx, S. Vanwing, V. Medo, R. Galvez, J. P. Miranda, C. Stone, T. Wigmore, Y. Arunan, A. Wheeler, Y. Wong, C. Poi, C. Gu, P. Molmy, N. Van Grunderbeeck, O. Nigeon, M. Lemyze, D. Thevenin, J. Mallat, M. Correa, R. T. Carvalho, A. Fernandez, C. McBride, E. Koonthalloor, C. Walsh, A. Webber, M. Ashe, K. Smith, E. A. Volakli, M. Dimitriadou, P. Mantzafleri, O. Vrani, A. Arbouti, T. Varsami, J. A. Bollen, T. C. Van Smaalen, W. C. De Jongh, M. M. Ten Hoopen, D. Ysebaert, L. W. Van Heurn, W. N. Van Mook, A. Roze des Ordons, P. Couillard, C. Doig, R. V. Van Keer, R. D. Deschepper, A. F. Francke, L. H. Huyghens, J. B. Bilsen, B. Nyamaizi, C. Dalrymple, A. Dobru, E. Marrinan, A. Ankuli, R. Struthers, R. Crawford, P. Mactavish, P. Morelli, M. Degiovanangelo, F. Lemos, V. MArtinez, J. Cabrera, A. Rutten, S. Van Ieperen, S. De Geer, M. Van Vugt, E. Der Kinderen, A. Giannini, G Miccinesi, T Marchesi, and E Prandi

Subjects
0301 basic medicine, 03 medical and health sciences, medicine.medical_specialty, 030219 obstetrics & reproductive medicine, 030104 developmental biology, 0302 clinical medicine, business.industry, Intensive care, Emergency medicine, Medicine, Critical Care and Intensive Care Medicine, business
Published
2016
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4. Predictors of Prolonged Mechanical Ventilation in Lung Cancer: Use of Noninvasive Ventilation

Author

Nikolaos Barbetakis and E. Antypa

Subjects
Mechanical ventilation, medicine.medical_specialty, Lung, business.industry, medicine.medical_treatment, Cancer, Disease, respiratory system, medicine.disease, Terminal cancer, respiratory tract diseases, medicine.anatomical_structure, Internal medicine, medicine, Cardiology, Noninvasive ventilation, In patient, Intensive care medicine, business, Lung cancer
Abstract

Although dyspnea is a well-known symptom of tumors involving the lung or pleura, shortness of breath is commonly present in patients with terminal cancer who do not have lung or pleura involvement. Dyspnea in cancer patients may be caused by the tumor itself, treatment of the tumor, medical complications of the debilitated state, or underlying lung or cardiac disease.

Published
2016
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5. Improving outcomes of severe infections by multidrug-resistant pathogens with polyclonal IgM-enriched immunoglobulins

Author

K. Mandragos, Christina Routsi, A. Prekates, Charalampos Gogos, Eleni Antoniadou, G. Vlachogiannis, V. Theodorou, E Antypa, N. Kapravelos, Evangelos J. Giamarellos-Bourboulis, C. Katsenos, Vasilios Koulouras, Apostolos Armaganidis, Nikolaos Tziolos, I. Pneumatikos, and Iraklis Tsangaris

Subjects
Microbiology (medical), Adult, Male, medicine.medical_specialty, bacteraemia, Antimicrobial resistance, law.invention, Sepsis, 03 medical and health sciences, 0302 clinical medicine, Antibiotic resistance, law, Internal medicine, Drug Resistance, Multiple, Bacterial, Medicine, Humans, Immunologic Factors, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Aged, Retrospective Studies, Aged, 80 and over, Greece, business.industry, Septic shock, IgM immunoglobulin, 030208 emergency & critical care medicine, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Intensive care unit, mortality, Survival Analysis, Intensive Care Units, Infectious Diseases, Treatment Outcome, Immunoglobulin M, Adjunctive treatment, Cohort, Immunology, septic shock, Female, business, Gram-Negative Bacterial Infections
Abstract

The emergence of infections by multidrug-resistant (MDR) Gram-negative bacteria, which is accompanied by considerable mortality due to inappropriate therapy, led to the investigation of whether adjunctive treatment with one polyclonal IgM-enriched immunoglobulin preparation (IgGAM) would improve outcomes. One hundred patients in Greece with microbiologically confirmed severe infections by MDR Gram-negative bacteria acquired after admission to the Intensive Care Unit and treated with IgGAM were retrospectively analysed from a large prospective multicentre cohort. A similar number of patient comparators well-matched for stage of sepsis, source of infection, appropriateness of antimicrobials and co-morbidities coming from the same cohort were selected. All-cause 28-day mortality was the primary end point; mortality by extensively drug-resistant (XDR) pathogens and time to breakthrough bacteraemia were the secondary end points. Fifty-eight of the comparators and 39 of the IgGAM-treated cases died by day 28 (p 0.011). The OR for death under IgGAM treatment was 0.46 (95% CI 0.26–0.85). Stepwise regression analysis revealed that IgGAM was associated with favourable outcome whereas acute coagulopathy, cardiovascular failure, chronic obstructive pulmonary disease and chronic renal disease were associated with unfavourable outcome. Thirty-nine of 62 comparators (62.9%) were infected by XDR Gram-negative bacteria and died by day 28 compared with 25 of 65 cases treated with IgGAM (38.5%) (p 0.008). Median times to breakthrough bacteraemia were 4 days and 10 days, respectively (p

Published
2015

6. Tigecycline for carbapenem-resistant Klebsiella pneumoniae infections in the intensive care unit

Author

Matthew E. Falagas, Dimitrios K. Matthaiou, E Antypa, Asimoula Koteli, Eleni Antoniadou, and Konstantinos Z. Vardakas

Subjects
Microbiology (medical), Male, medicine.medical_specialty, Carbapenem resistant Klebsiella pneumoniae, Klebsiella pneumoniae, Minocycline, Tigecycline, Drug resistance, law.invention, Pharmacotherapy, law, Drug Resistance, Bacterial, Medicine, Humans, Intensive care medicine, Aged, General Immunology and Microbiology, biology, business.industry, Critically ill, General Medicine, Middle Aged, biology.organism_classification, Intensive care unit, Klebsiella Infections, Intensive Care Units, Infectious Diseases, Carbapenems, Drug Therapy, Combination, Female, business, medicine.drug
Abstract

To the Editor, A report on the use of tigecycline for treatment of carbapenem-resistant Klebsiella pneumoniae (CRKp) infections in critically ill patients was recently published in this journal [1]...

Published
2015

7. Characteristics, risk factors and outcomes of carbapenem-resistant Klebsiella pneumoniae infections in the intensive care unit

Author

Konstantinos Z. Vardakas, Asimoula Koteli, Eleni Antoniadou, Matthew E. Falagas, Dimitrios K. Matthaiou, and E Antypa

Subjects
Microbiology (medical), Male, medicine.medical_specialty, Multivariate analysis, Isolation (health care), Klebsiella pneumoniae, Bacteremia, law.invention, law, Risk Factors, Internal medicine, Drug Resistance, Multiple, Bacterial, Medicine, Humans, Intensive care medicine, APACHE, Aged, Retrospective Studies, Aged, 80 and over, APACHE II, biology, business.industry, Retrospective cohort study, Middle Aged, biology.organism_classification, medicine.disease, Intensive care unit, Anti-Bacterial Agents, Klebsiella Infections, Intensive Care Units, Infectious Diseases, Respiratory failure, Carbapenems, Case-Control Studies, Female, business
Abstract

Summary Objective To study the characteristics, risk factors and outcomes of intensive care unit (ICU) patients with carbapenem-resistant (CRKp) and carbapenem-susceptible (CSKp) Klebsiella pneumoniae infections. Methods A retrospective cohort of patients with K. pneumoniae infections in an eight-bed ICU between January 2006 and October 2009. Results During the study period, 104 patients were diagnosed with K. pneumoniae infection (80 CRKp and 24 CSKp). Isolation of CRKp increased gradually during the study period, while isolation of CSKp remained constant. The mean age of patients was 66.3 ± 14.3 years. The mean APACHE II score was 17.9 ± 6.9. The median duration of ICU stay until the infection was 15 days. Thirty five patients (33.7%) had primary and 30 (28.8%) had secondary bacteremia. Seventy-two patients (69.2%) died in the ICU. No independent risk factors for development of CRKp infections were identified in the multivariate analysis. Treatment failure ( p = 0.001) was the only independent predictor of mortality in the multivariate analysis (APACHE II, shock, multi-organ failure, respiratory failure, acute renal failure, acidosis and extensive-drug resistance were included in the model). No difference in mortality was found between patients with CRKp and CSKp isolates. Conclusions Infection due to K. pneumoniae in the ICU was associated with high mortality. Control of the infection was the most important determinant of the outcome of critically ill patients.

Published
2014

8. Ultrasound contrast agent delivered per os first diagnoses pharyngoesophageal tumour

Author

E. Antypa, Pn N. Piperopoulos, Dd D. Cokkinos, D. Tomais, and I. Kalogeropoulos

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, Adult, Male, medicine.medical_specialty, Esophageal Neoplasms, lcsh:R895-920, media_common.quotation_subject, Biopsy, Sulfur Hexafluoride, Administration, Oral, Contrast Media, Ultrasound (US), Diagnosis, Differential, Oral administration, medicine, Contrast (vision), Humans, Medical diagnosis, Phospholipids, media_common, Ultrasonography, contrast media, medicine.diagnostic_test, business.industry, Ultrasound, Pharyngeal Neoplasms, Carcinoma, Squamous Cell, Radiology, Esophagoscopy, business, Medical literature
Abstract

Oral administration of ultrasound contrast agents has been described very little so far in medical literature. These agents are mainly administered intravenously and, less commonly, intracavitarily. We present the case of a patient with a cervical mass in whom sonographic examination with per os administration of SonoVue led to the diagnosis of a pharyngoesophageal tumour. The diagnosis was confirmed on barium swallow and endoscopy-guided biopsy.

Published
2013

9. Contrast-enhanced ultrasound for imaging blunt abdominal trauma - indications, description of the technique and imaging review

Author

V. Kostaras, D. D. Cokkinos, P. Tserotas, K. Stefanidis, A. Parlamenti, P. N. Piperopoulos, K. Tavernaraki, and E. Antypa

Subjects
medicine.medical_specialty, Point-of-Care Systems, Contrast Media, Abdominal Injuries, Wounds, Nonpenetrating, Sensitivity and Specificity, Blunt, medicine, Humans, Radiology, Nuclear Medicine and imaging, Hemoperitoneum, Ultrasonography, Abdominal Fluid, business.industry, Multiple Trauma, Ultrasound, medicine.disease, Image Enhancement, medicine.anatomical_structure, Abdominal trauma, Abdomen, Radiology, Tomography, medicine.symptom, business, Tomography, X-Ray Computed, Contrast-enhanced ultrasound, Extravasation of Diagnostic and Therapeutic Materials, Follow-Up Studies
Abstract

Patients with blunt abdominal trauma are initially imaged with ultrasound (US) for the evaluation of free abdominal fluid. However, lacerations of solid organs can be overlooked. Although computed tomography (CT) is the gold standard technique for abdominal trauma imaging, overutilization, ionizing radiation, need to transport the patient and potential artifacts are well known disadvantages. Contrast-enhanced US (CEUS) can be used as an imaging tool between the two methods. It can easily and reliably reveal solid abdominal organ injuries in patients with low-energy localized trauma and decrease the number of CT scans performed. It can be rapidly performed at the patient's bedside with no need for transportation. There are only very few contraindications and anaphylactoid reactions are extremely rare. Altogether, CEUS has proved to be very helpful for the initial imaging of traumatic lesions of the liver, kidney and spleen, as well as for patient follow-up.

Published
2012

10. Serum beta-endorphin response to stress before and after operation under fentanyl anesthesia in neonates, infants and preschool children

Author

Petros Mirilas, Elissaios Kontis, E. Antypa, Anastasia Mentessidou, Anastasios Petropoulos, and A. Makedou

Subjects
Male, Surgical stress, Fentanyl, chemistry.chemical_compound, medicine, Humans, Propofol, Endogenous opioid, Pain, Postoperative, Morphine, business.industry, beta-Endorphin, Infant, Newborn, Infant, Analgesics, Opioid, Treatment Outcome, chemistry, Opioid, Anesthesia, Child, Preschool, Pediatrics, Perinatology and Child Health, Anesthesia, Intravenous, Anxiety, Surgery, Female, medicine.symptom, business, Anesthetics, Intravenous, Stress, Psychological, medicine.drug
Abstract

INTRODUCTION The endogenous opioid beta-endorphin is a known indicator of stress and pain. Opioid anesthesia during operation may prevent postoperative beta-endorphin hypersecretion. We examine the effect on serum beta-endorphin of both preoperative stress and stress of operation under opioids in neonates, infants and preschool children. In order to eliminate the effect of hospitalization anxiety we compared with inpatients of similar age with non-surgical disease. MATERIAL AND METHODS We included 74 surgical patients (25 neonates, 24 infants, 25 preschool children), and 44 non-surgical inpatients (14 neonates, 12 infants, 18 preschool children). Anesthesia comprised propofol and fentanyl. In presence of pain after extubation, supplementary morphine was administered. Sera were taken preoperatively and 2 h postoperatively in surgical patients, and once in non-surgical patients. Beta-endorphin was tested using ELISA (ng/ml). RESULTS In all surgical patients beta-endorphin did not increase significantly after surgery. Neonates showed significantly elevated beta-endorphin preoperatively (mean+/-SD: 2.02+/-0.76) and postoperatively (2.07+/-0.90) compared to neonates with a non-surgical disease (1.05+/-0.34; p

Published
2010

12. Risk factors associated with Acinetobacter baumannii septicemia and its mortality rates in critically ill patients

Author

Konstantina Kontopoulou, P Tassioudis, K Tsepanis, Eleni Antoniadou, A Triantafyllidou, K Mandraveli, E Chasou, E Antypa, F Renta, I Sgouropoulos, and D Socratous

Subjects
medicine.medical_specialty, biology, business.industry, Critically ill, Mortality rate, High mortality, bacterial infections and mycoses, Critical Care and Intensive Care Medicine, medicine.disease, biology.organism_classification, Acinetobacter baumannii, Bacteremia, Poster Presentation, medicine, Intensive care medicine, business
Abstract

Acinetobacter baumannii (A. baum) is a leading cause of septicemia of patients hospitalized in the ICU with high mortality rates. The aim of our study is to investigate the risk factors associated with A. baum bacteremia and its mortality rates.

Published
2013

13. Risk factors for the development of carbapenem-resistant Klebsiella pneumoniae infections in critically ill patients

Author

Konstantinos Z. Vardakas, Eleni Antoniadou, E Chasou, Alexandros P. Grammatikos, Dimitrios K. Matthaiou, and E Antypa

Subjects
medicine.medical_specialty, Icu patients, Critically ill, Carbapenem resistant Klebsiella pneumoniae, business.industry, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Critical Care and Intensive Care Medicine, Poster Presentation, polycyclic compounds, medicine, bacteria, Intensive care medicine, business
Abstract

We sought to study the characteristics and outcomes of ICU patients with carbapenem-resistant (CRKp) and carbapenem-sensitive (CSKp) K. pneumoniae infections.

Published
2010
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14. Antimicrobial resistance pattern of Pseudomonas aeruginosa in clinical isolates from ICU patients

Author

Konstantina Kontopoulou, Eleni Antoniadou, A Kiparissi, Asimoula Koteli, and E Antypa

Subjects
medicine.medical_specialty, Imipenem, Pseudomonas aeruginosa, business.industry, Ceftazidime, Critical Care and Intensive Care Medicine, medicine.disease_cause, medicine.disease, Meropenem, Microbiology, Antibiotic resistance, Amikacin, Bacteremia, Poster Presentation, medicine, Tobramycin, Intensive care medicine, business, medicine.drug
Abstract

Pseudomonas aeruginosa remains one of the most important pathogens in the nosocomial setting, where it is a common causative agent of bacteremia [1,2]. The aim of this study was to evaluate the antimicrobial resistance of Pseudomonas spp. strains isolated from inpatients hospitalized in the ICU of our hospital throughout a 3-year period.

Published
2009

15. Risk factors of candidemia in postoperative ICU patients: a prospective study

Author

N Voloudakis, E Chassou, Konstantina Kontopoulou, E Antypa, Eleni Antoniadou, and I Sgouropoulos

Subjects
Icu patients, medicine.medical_specialty, business.industry, biochemical phenomena, metabolism, and nutrition, equipment and supplies, bacterial infections and mycoses, Critical Care and Intensive Care Medicine, fluids and secretions, hemic and lymphatic diseases, Poster Presentation, Emergency medicine, Medicine, business, Intensive care medicine, Prospective cohort study
Abstract

The prediction for and the mortality of patients with candidemia are highly adverse. The aim of this study was to identify the risk factors for the development of candidemia in postoperative patients.

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16. Infections from MDR strains (K. pneumoniae, P. aeruginosa, A. Baumannii complex) in a multivalent ICU

Author

Eleni Antoniadou, Konstantina Kontopoulou, P Tasioudis, I Sgouropoulos, E Antypa, and G Voloudakis

Subjects
medicine.medical_specialty, Pediatrics, Icu patients, business.industry, Potential risk, health care facilities, manpower, and services, Internal medicine, Poster Presentation, medicine, K pneumoniae, business, Critical Care and Intensive Care Medicine, A baumannii
Abstract

The infection incidences from MDR strains in our ICU are in accordance with the results of respective studies in other ICUs of our country. Our aim is to identify potential risk factors for the development of MDR infection in ICU patients.

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