1. A Newly Developed mm-Wave Sensor for Detecting Plaques of Arterial Vessels
- Author
-
Ilona Rolfes, Georg Rose, Sebastian Vogt, Anette Ramaswamy, Wilhelm Nimphius, Subhajit Guha, Christian Wenger, Farabi Ibne Jamal, Christoph Baer, Jan Wessel, Betram Schmidt, Rabia Ramzan, Ulrich Schumann, Thomas Musch, Gordon Notzon, David W. Wagner, Christoph Dahl, Mohammed Hussein Eissa, and Markus Detert
- Subjects
Calcium Phosphates ,0301 basic medicine ,Pulmonary and Respiratory Medicine ,Catheters ,Biopsy ,Sus scrofa ,Transducers ,Microwave technology ,Dielectric ,030204 cardiovascular system & hematology ,Electric Capacitance ,Capacitance ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Predictive Value of Tests ,medicine ,Animals ,Humans ,Vascular Calcification ,Miniaturization ,Tissue water ,business.industry ,Fibrous cap ,Detector ,Arteries ,Equipment Design ,Hydroxylapatite ,Atherosclerosis ,Fibrosis ,Plaque, Atherosclerotic ,Durapatite ,030104 developmental biology ,medicine.anatomical_structure ,chemistry ,Dielectric Spectroscopy ,Extremely high frequency ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Biomedical engineering - Abstract
Background Microcalcifications within the fibrous cap of the arteriosclerotic plaques lead to the accrual of plaque-destabilizing mechanical stress. New techniques for plaque screening with small detectors and the ability to differentiate between the smooth and hard elements of plaque formation are necessary. Method Vascular plaque formations are characterized as calcium phosphate containing structures organized as hydroxylapatite resembling the mineral whitlockite. In transmission and reflexion studies with a simple millimeter wave (mm-wave)–demonstrator, we found that there is a narrow window for plaque detection in arterial vessels because of the tissue water content, the differentiation to fatty tissue, and the dielectric property of air or water, respectively. Result The new sensor is based on a sensing oscillator working around 27 GHz. The open-stub capacitance determines the operating frequency of the sensor oscillator. The capacitance depends on the dielectric properties of the surrounding material. The sensor components were completely built up in surface mount technique. Conclusion Completed with a catheter, the sensor based on microwave technology appears as a robust tool ready for further clinical use.
- Published
- 2017
- Full Text
- View/download PDF