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1. NOW serving: PREVENTION: Proper PPE combats high rate of injuries in food and beverage manufacturing

Author: Cavallaro, David
Subjects: Work-related injuries -- Prevention, Cleaning compounds -- Production processes, Business, general, Business, Engineering and manufacturing industries
Abstract: The food and beverage industry is the third Largest manufacturing sector in the U.S., employing just about 1.7 million workers across nearly 40,000 processing plants. Given the multitude of plants [...]
Published: 2023

2. Implementing a SAFETY-FIRST CULTURE: Everyone needs to work together to protect construction workers

Author: Cavallaro, David
Subjects: Occupational health and safety, Construction workers, Business, general, Business, Engineering and manufacturing industries
Abstract: Construction workers face many workplace dangers on a daily basis, and ensuring proper safety is a vital component of the job to prevent injuries and even fatalities. And it's not [...]
Published: 2023

3. Sustained symptomatic remission in schizophrenia: Course and predictors from a two-year prospective study

Author: Mirko Manchia, Massimo Tusconi, Bernardo Carpiniello, Federica Pinna, Roberto Cavallaro, Marta Bosia, Carpiniello, B., Pinna, F., Manchia, M., Tusconi, M., Cavallaro, R., and Bosia, M.
Subjects: Psychosis, medicine.medical_specialty, Duration of illness, Schizoaffective disorder, Basal (phylogenetics), Internal medicine, medicine, Humans, Prospective Studies, Prospective cohort study, Cognitive symptoms, Biological Psychiatry, Survival analysis, Psychiatric Status Rating Scales, Positive and Negative Syndrome Scale, business.industry, Regression analysis, Antipsychotic treatment, Positive and negative syndrome scale, medicine.disease, Clinical setting, Psychiatry and Mental health, Treatment Outcome, Psychotic Disorders, Schizophrenia, Schizophrenic Psychology, business, Antipsychotic Agents, Follow-Up Studies
Abstract: Background Although remission is a priority target in psychosis, reported rates show a marked variation across studies and instability over time. Such variability, partly due to methodology, emphasizes the need to define the optimal assessment procedure, as well as to identify reliable predictors. This study aims to: 1. longitudinally compare remission status according to different criteria; 2. identify predictors of duration and stability. Methods 112 patients with schizophrenia or schizoaffective disorder underwent comprehensive clinical evaluations, with 24-month follow-up. Remission was assessed using three criteria: Remission in Schizophrenia Working Group (RSWG) vs Positive and Negative Syndrome Scale (PANSS) positive and negative scales (PANSS-PN) vs total score (PANSS-T). Kaplan-Meier survival analysis was used for longitudinal comparison, regression models to identify predictors of duration and stability. Results At enrolment 50% of patients were in remission according to RSWG, while only 23.2% reached the other criteria. PANSS-T cumulative remission rates showed the greatest stability. Stable remission according to RSWG criteria was predicted by negative symptoms, while no significant predictors emerged for PANSS-T. Remission duration was predicted by negative, positive and cognitive symptoms and treatment dosage for RSWG criteria, while for PANSS-T the predictors were cognitive symptoms and duration of illness. Conclusion Results are in line with previous literature on remission rates and further support the role of basal clinical predictors. In addition, this study shows that more stringent criteria are more stable over time, suggesting their predictive value and the relevance of their use to optimize evaluations also in clinical settings.
Published: 2022
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4. Safety and clinical efficacy of the double switch from originator infliximab to biosimilars CT‐P13 and SB2 in patients with inflammatory bowel diseases (SCESICS): A multicenter cohort study

Author: Flavio Caprioli, Maurizio Vecchi, Nicole Piazza O. Sed, Chiara Ricci, Carlo Maria Girelli, Pietro Invernizzi, Luca Ferraris, Beatrice Marinoni, Stefano Mazza, Gionata Fiorino, Alice Colucci, Flaminia Cavallaro, G. Lupinacci, Luca Pastorelli, Alessandro Rimondi, Francesca Munari, Lorena Pirola, Arnaldo Amato, F.S. Conforti, Alberto Fasci, V. Casini, Gian Eugenio Tontini, Mazza, S, Piazza, O, Conforti, F, Fasci, A, Rimondi, A, Marinoni, B, Casini, V, Ricci, C, Munari, F, Pirola, L, Invernizzi, P, Girelli, C, Lupinacci, G, Pastorelli, L, Cavallaro, F, Ferraris, L, Colucci, A, Amato, A, Eugenio Tontini, G, Vecchi, M, Fiorino, G, and Caprioli, F
Subjects: Adult, Male, medicine.medical_specialty, Adolescent, RM1-950, General Biochemistry, Genetics and Molecular Biology, Article, Cohort Studies, Young Adult, Internal medicine, medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, Adverse effect, Biosimilar Pharmaceuticals, business.industry, Drug Substitution, General Neuroscience, Incidence (epidemiology), Research, Antibodies, Monoclonal, Common Terminology Criteria for Adverse Events, General Medicine, Articles, Inflammatory Bowel Diseases, Infliximab, Confidence interval, Discontinuation, ECCO POSITION STATEMENTDOUBLE-BLINDCROHNS-DISEASEITALIAN GROUPTHERAPYIMMUNOGENICITYSOCIETYINDEXIBD, Treatment Outcome, Propensity score matching, Female, Therapeutics. Pharmacology, Public aspects of medicine, RA1-1270, business, medicine.drug, Cohort study
Abstract: Data regarding double switching from originator infliximab (IFX) to IFX biosimilars in inflammatory bowel diseases (IBDs) are lacking. The purpose of this study was to evaluate the safety and efficacy of switching from originator IFX to CT-P13 and subsequently to SB2 (double switch) in patients with IBD. Patients undergoing IFX-double switch in eight Centers in Lombardy (Italy) from November 2018 to May 2019 were retrospectively analyzed. The IFX discontinuation rate, incidence and type of adverse events (AEs), and clinical remission rate were recorded. A comparison with a control group of patients with IBD single-switched from originator IFX to CT-P13 was performed, before and after an inverse probability of treatment weighting (IPTW)-based propensity score analysis. Fifty-two double-switched patients with IBD were enrolled. The 24- and 52-week proportions of patients continuing on IFX therapy following the second switch (CTP13→SB2) were 98% (95% confidence interval [CI] 94%–100%) and 90% (95% CI 81%–99%), respectively. Four patients experienced a total of five AEs, all graded 1–3 according to Common Terminology Criteria for Adverse Events (CTCAE). No infusion reactions were observed. The 24-week and follow-up end clinical remission rates following the second switch were 94% and 88%, respectively. No differences were observed in the safety and efficacy outcomes by comparing the double-switch group with a single-switch group of 66 patients with IBD; all these results were confirmed by IPTW-adjusted analysis. The study suggests both the safety and efficacy of the double switch from originator IFX to CT-P13 and SB2 in patients with IBD is maintained. This strategy may be associated with potential cost implications.
Published: 2021

5. Association of age with treatment at high-volume hospitals and distance traveled for care, in patients with rectal cancer who seek curative resection

Author: Rocco Ricciardi, Grace C. Lee, Liliana Bordeianou, Paul M Cavallaro, Naomi M. Sell, Todd D. Francone, Hiroko Kunitake, and Lewis A. Lipsitz
Subjects: Curative resection, Travel, medicine.medical_specialty, Proctectomy, Rectal Neoplasms, business.industry, Colorectal cancer, General surgery, General Medicine, Middle Aged, medicine.disease, Health Services Accessibility, Resection, Hospital volume, Older patients, Humans, Medicine, Surgery, In patient, business, Hospitals, High-Volume, Aged, Retrospective Studies, Volume (compression)
Abstract: Background The association between volume and outcomes has led to recommendations that patients undergo surgery at high-volume centers. We aimed to determine if older patients with rectal cancer are undergoing operations at high-volume centers. Methods We identified patients ≥50 years old who underwent rectal cancer resection using the NCDB (2004–2015). Tertiles were used to categorize facility volume and distance traveled. Results Higher facility volume was associated with improved outcomes. Patients >75 years old were less likely than patients 50–59 years old to be treated at high-volume centers. Traveling >16.8 miles was associated with treatment at high-volume facilities, however patients >75 years old were less likely to travel >16.8 miles. Conclusions Higher facility volume is associated with improved outcomes after rectal cancer resection. However, older patients are less likely to be treated at high-volume facilities. Older patients travel shorter distances for care, suggesting that care integration across networks must be optimized.
Published: 2022
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6. Clinical phenotypes for risk stratification in small‐for‐gestational‐age fetuses

Author: Juan L. Delgado, José Villar, C Paules, A. Cavallaro, Daniel Oros, Aris T. Papageorghiou, S. Ruiz-Martinez, and C. De Paco
Subjects: medicine.medical_specialty, Placenta, Intrauterine growth restriction, Risk Assessment, Fetus, Pregnancy, medicine, Humans, Radiology, Nuclear Medicine and imaging, reproductive and urinary physiology, Fetal Growth Retardation, Radiological and Ultrasound Technology, Obstetrics, business.industry, Infant, Newborn, Obstetrics and Gynecology, General Medicine, Odds ratio, medicine.disease, Confidence interval, Gestational diabetes, Phenotype, Reproductive Medicine, Infant, Small for Gestational Age, Cohort, Premature Birth, Small for gestational age, Gestation, Female, business, Cohort study
Abstract: Objective This study evaluates whether clinical phenotypes of small for gestational (SGA) fetuses can be identified and used for adverse perinatal outcome risk stratification to facilitate decision-making. Methods This multicentre observational cohort study was conducted in two tertiary care university hospitals. It included 17,631 consecutive singleton pregnancies, among which 1274 (7.2%) were defined as SGA at birth according to INTERGROWTH-21st standards. The main outcome was the development of clinical clusters of SGA phenotypes. Results Nine SGA clinical phenotypes were identified using a predefined conceptual framework. Every delivery and perinatal outcome analysed showed statistically significant differences between phenotypes. The total SGA cohort had a 3 times increased risk of perinatal mortality than non-SGA fetuses (1.4% vs 0.4%; pConclusions We identified nine SGA clinical phenotypes associated with different patterns of risk for adverse perinatal outcomes. Our results suggest that adding clinical characteristics to ultrasound results would improve risk stratification and decision-making for SGA fetuses. Future clinical trials on the control of fetuses with SGA should take into account, in addition to Doppler and estimated fetal weight, this clinical information.
Published: 2022
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7. Spontaneous psoas haematoma: a life-threatening complication of anticoagulation in COVID-19. A case series of four episodes

Author: Mauro Giuffrè, Alessandro Marco Bozzato, Anna Di Giusto, Sofia Battisti, Verena Zerbato, Paola Martingano, Roberto Luzzati, Stefano Di Bella, Maria Assunta Cova, Marco Cavallaro, Zerbato, Verena, Bozzato, Alessandro Marco, Di Bella, Stefano, Giuffrè, Mauro, Martingano, Paola, Di Giusto, Anna, Battisti, Sofia, Cova, Maria Assunta, Luzzati, Roberto, and Cavallaro, Marco Francesco Maria
Subjects: 0301 basic medicine, Microbiology (medical), Pediatrics, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Spontaneous psoas haematoma, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), 030106 microbiology, 03 medical and health sciences, 0302 clinical medicine, Anticoagulant prophylaxis, medicine, Humans, COVID-19, SARS-CoV-2, anticoagulation, 030212 general & internal medicine, Aged, Aged, 80 and over, Hematoma, General Immunology and Microbiology, business.industry, Anticoagulants, Venous Thromboembolism, General Medicine, Middle Aged, medicine.disease, Pneumonia, Infectious Diseases, Complication, business, Venous thromboembolism
Abstract: Background: Anticoagulant prophylaxis is part of the standard management of hospitalized COVID-19 patients. Despite adequate thromboprophylaxis, one-third of COVID-19 patients with pneumonia developed pulmonary embolism. This high rate of thrombotic complications has led to higher doses of anticoagulants according to clinical complexity (e.g. intensive care unit (ICU) patients) and D-dimer levels. On the other side of the coin, haemorrhagic complications are being increasingly reported. Cases presentation: We herein report four cases of spontaneous psoas haematomas (SPH) among 548 patients hospitalized for SARS-CoV-2 pneumonia between March 2020 and January 2021 (incidence of 7.3 cases per 1000 patients). All patients had pneumonia, with age ranging between 62 and 83 years. All patients received anticoagulant therapy with low weight molecular heparin (100 U.I. anti-Xa/kg 2 times/d) from admission: in two cases, a diagnosis of pulmonary embolism was made. In another case, a thrombosis of left axillary and basilic veins was found, and only in one case anticoagulant therapy was started because of elevated levels of D-dimer. In all cases, signs of anaemia were detected and patients experienced low back or abdominal pain. The diagnosis of spontaneous psoas haematoma was made by computed tomography (CT) after a median of 12.5 d (9;16) from admission and 19.5 d (14.75; 24.25) from the beginning of COVID-19 symptoms. Half of these patients died from haemorrhagic shock. Conclusions: Given the potential life-threatening of SPH and the possible subtle clinical presentation, we believe it is crucial to raise clinicians awareness of this complication among COVID-19 patients undergoing anticoagulants.
Published: 2021
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8. Audio-Visual Tracking of Concurrent Speakers

Author: Xinyuan Qian, Alessio Brutti, Andrea Cavallaro, Oswald Lanz, and Maurizio Omologo
Subjects: Computer science, BitTorrent tracker, business.industry, Computation, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Image plane, Tracking (particle physics), Computer Science Applications, Image (mathematics), Task (computing), Discriminative model, Signal Processing, Media Technology, Computer vision, Artificial intelligence, Electrical and Electronic Engineering, business, Particle filter
Abstract: Audio-visual tracking of an unknown number of concurrent speakers in 3D is a challenging task, especially when sound and video are collected with a compact sensing platform. In this paper, we propose a tracker that builds on generative and discriminative audio-visual likelihood models formulated in a particle filtering framework. We localize multiple concurrent speakers with a de-emphasized acoustic map assisted by the image detection-derived 3D video observations. The 3D multimodal observations are either assigned to existing tracks for discriminative likelihood computation or used to initialize new tracks. The generative likelihoods rely on color distribution of the target and the de-emphasized acoustic map value. Experiments on AV16.3 and CAV3D datasets show that the proposed tracker outperforms the uni-modal trackers and the state-of-the-art approaches both in 3D and on the image plane.
Published: 2022
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9. Going Home with a Patent Ductus Arteriosus: Is it Benign?

Author: Stephania Cavallaro Moronta, Adrianne Rahde Bischoff, and Patrick J. McNamara
Subjects: medicine.medical_specialty, business.industry, Infant, Newborn, Infant, Infant, Low Birth Weight, Patient Discharge, medicine.anatomical_structure, Ductus arteriosus, Internal medicine, Pediatrics, Perinatology and Child Health, medicine, Cardiology, Humans, Prospective Studies, business, Ductus Arteriosus, Patent, Infant, Premature
Published: 2022
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10. Deep Learning Assisted Time-Frequency Processing for Speech Enhancement on Drones

Author: Lin Wang and Andrea Cavallaro
Subjects: Beamforming, Signal processing, Control and Optimization, Spatial filter, business.industry, Computer science, Speech recognition, Deep learning, Direction of arrival, Context (language use), Computer Science Applications, Speech enhancement, Reduction (complexity), Computational Mathematics, Artificial Intelligence, Artificial intelligence, business
Abstract: This article fills the gap between the growing interest in signal processing based on Deep Neural Networks (DNN) and the new application of enhancing speech captured by microphones on a drone. In this context, the quality of the target sound is degraded significantly by the strong ego-noise from the rotating motors and propellers. We present the first work that integrates single-channel and multi-channel DNN-based approaches for speech enhancement on drones. We employ a DNN to estimate the ideal ratio masks at individual time-frequency bins, which are subsequently used to design three potential speech enhancement systems, namely single-channel ego-noise reduction (DNN-S), multi-channel beamforming (DNN-BF), and multi-channel time-frequency spatial filtering (DNN-TF). The main novelty lies in the proposed DNN-TF algorithm, which infers the noise-dominance probabilities at individual time-frequency bins from the DNN-estimated soft masks, and then incorporates them into a time-frequency spatial filtering framework for ego-noise reduction. By jointly exploiting the direction of arrival of the target sound, the time-frequency sparsity of the acoustic signals (speech and ego-noise) and the time-frequency noise-dominance probability, DNN-TF can suppress the ego-noise effectively in scenarios with very low signal-to-noise ratios (e.g. SNR lower than −15 dB), especially when the direction of the target sound is close to that of a source of the ego-noise. Experiments with real and simulated data show the advantage of DNN-TF over competing methods, including DNN-S, DNN-BF and the state-of-the-art time-frequency spatial filtering.
Published: 2021
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11. A Complex Band-Pass Filter for Low-Power and High-Performance Transceivers

Author: Marco Cavallaro and Germano Nicollini
Subjects: Computer science, business.industry, Amplifier, Bandwidth (signal processing), Electrical engineering, Topology (electrical circuits), Noise (electronics), Power (physics), Band-pass filter, CMOS, Filter (video), Hardware_INTEGRATEDCIRCUITS, Electrical and Electronic Engineering, business
Abstract: In this paper a low-power and high-performance 2nd-order complex band-pass filter in trans-impedance amplifier (TIA) configuration is presented. Thanks to the adopted topology for the passive network and active-components exceeds current solutions exhibiting a gain as high as 121.5 dB $_Ω$ and 1.57 MHz of bandwidth centered around 1.33 MHz. The output noise is only 630 nV/√Hz. Furthermore, a new fully-differential class-AB operational trans-conductance amplifier (OTA) provides the required current to drive heavy ADC loads with very fast signals while an improved common-mode feedback circuit enables ultra low current without introducing stability and avoids start-up problems. The filter has been integrated in a 90-nm complementary metal oxide semiconductor (CMOS) technology. Despite the high performance and accuracy of the transfer function the power consumption is only 400 μA from a 1.2-V power supply.
Published: 2021
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12. Antenatal magnesium sulphate for preventing cerebral palsy: An economic evaluation of the impact of a quality improvement program

Author: Sarah McIntyre, Alice R. Rumbold, Angela Cavallaro, Charlotte Groves, Emily J. Callander, Amy Keir, Caroline A Crowther, and Emily Shepherd
Subjects: medicine.medical_specialty, Quality management, Cost-Benefit Analysis, Perinatal care, Cerebral palsy, Magnesium Sulfate, Pregnancy, Health care, medicine, Humans, Child, health care economics and organizations, Cost–benefit analysis, business.industry, Cerebral Palsy, Incidence (epidemiology), Obstetrics and Gynecology, General Medicine, medicine.disease, Quality Improvement, Cost savings, Neuroprotective Agents, Economic evaluation, Emergency medicine, Premature Birth, Female, business
Abstract: Previous work demonstrated that implementing a quality improvement (QI) program improves the uptake of guideline-recommended antenatal magnesium sulphate, a critical intervention known to reduce cerebral palsy risk. Here we estimate potential cost savings attributable to the improved uptake. By expanding coverage from 63 to 83% of eligible women, we estimated that five children potentially would not have received a diagnosis of cerebral palsy, a potential cost saving of $AU4.8 million in lifetime healthcare costs. Our findings strengthen the case for embedding QI approaches in perinatal care to reduce the incidence of cerebral palsy.
Published: 2021
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13. Finite element modeling of an energy storing and return prosthetic foot and implications of stiffness on rollover shape

Author: Carlo Ferraresi, Giovanni Milandri, Matteo Laffranchi, Lorenzo De Michieli, Federico Tessari, Lorenzo Cavallaro, and Carlo De Benedictis
Subjects: Finite Element Analysis, Artificial Limbs, Walking, Prosthesis Design, Prosthetic foot, finite element analysis, foot stiffness, rollover shape, Amputees, medicine, Gait, Prosthetic feet, Foot, business.industry, Mechanical Engineering, FOOT STIFFNESS, Stiffness, General Medicine, Structural engineering, Rollover, Finite element method, Biomechanical Phenomena, medicine.symptom, business, Energy (signal processing), Geology, Foot (unit)
Abstract: Energy storing and return (ESAR) prosthetic feet showed continuous improvements during the last 30 years. Despite this, standard guidelines are still missing to achieve an optimal foot design in terms of performances. One of the most important design parameters in ESAR feet is the Rollover Shape (RoS). This represents the foot Center of Pressure (CoP) path in a shank-based coordinate system during stance. RoS objectively describes the foot behavior according to its stiffness, which depends on foot geometry and material. This work presents the development of a finite element modeling methodology able to predict the stiffness characteristic of an ESAR foot and its RoS. The validation of the model is performed on a well-known commercially available prosthetic foot both in bench tests and realistic walking scenario. The obtained results confirm an error of +6.1% on stiffness estimation and +10.2% on RoS evaluation, which underlines that the proposed method is a powerful tool able to replicate the mechanical behavior of a prosthetic foot.
Published: 2021
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14. Bolus intravenous 0.9% saline leads to interstitial permeability pulmonary edema in healthy volunteers

Author: Elena Cavallaro, Shailesh Bihari, Hanmo Li, Ubbo F Wiersema, Dani-Louise Dixon, David Schembri, and Andrew D. Bersten
Subjects: medicine.diagnostic_test, Physiology, business.industry, medicine.medical_treatment, Public Health, Environmental and Occupational Health, General Medicine, Lung injury, Doppler echocardiography, Pulmonary edema, medicine.disease, Pulmonary function testing, Bolus (medicine), Bronchoalveolar lavage, Physiology (medical), Anesthesia, medicine, Orthopedics and Sports Medicine, business, Saline, Blood sampling
Abstract: Bolus intravenous administration of 0.9% saline has been associated with the development of pulmonary edema, and increased mortality. An animal model has previously demonstrated that rapid intravenous administration of 0.9% saline was associated with non-hydrostatic lung injury with increased lung lavage protein. We hypothesized that this non-hydrostatic effect would also occur in human volunteers. In a randomized, cross-over study of 14 healthy male subjects, the lung lavage protein concentration and cardiorespiratory effects of an intervention with rapid intravenous administration of 30 mL/kg of 0.9% saline were compared with sham intervention. Bronchoalveolar lavage (BAL) was performed after fluid administration. Doppler echocardiography, lung ultrasound, pulmonary function tests, and blood sampling were performed before and after each intervention. The BAL total protein concentration was greater after 0.9% saline administration than with sham (196.1 µg/mL (SD 87.6) versus 129.8 µg/mL (SD 55.4), respectively (p = 0.020). Plasma angiopoietin-2 concentration was also increased to 2.26 ng/mL (SD 0.87) after 0.9% saline administration compared with sham 1.53 ng/mL (SD 0.69) (p
Published: 2021
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15. Problems of sleep, depression, quality of life in adolescents with TMD diagnosis

Author: Danilo Antônio Duarte, Karla Christina Amaral de Pinto Costa, Giselle Rodrigues de Sant'Anna, Kelly Maria Silva Moreira, José Carlos Pettorossi Imparato, Victor Cavallaro Bottesini, and Stela Maris Wanderley Rocha
Subjects: stomatognathic diseases, medicine.medical_specialty, Quality of life (healthcare), business.industry, Medicine, General Medicine, business, Psychiatry, Sleep in non-human animals, Depression (differential diagnoses)
Abstract: Aim: To verify the relationship between temporal-mandibular dysfunction (TMD) with depression, sleep, sleepiness and quality of life in adolescents aged 13 to 18 years old. Methods: Thirty-eight adolescents being seen at the UFAL Dental Clinic (Federal University of Alagoas), for TMD, and qualifying according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC / TMD), participated in the study. Two instruments were used to investigate sleep quality: the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS); the Oral Health Impact Profile (OHIP-14) for quality-of-life assessment; and the Beck Depression Inventory (BDI-II) for depression assessment. Pearson’s correlation coefficient was used for the relationship of numerical variables. For the means tests, the Student t test was applied (using, when necessary, the Welch correction). For the analyses, the Bonferroni correction was considered. Results: After calculation, αBonferroni correction was applied equal to 0,0005. Of the total number of participants (56% female and 44% male), with a mean age of 14.7). In all comparisons between groups (with and without TMD), there were statistically significant indices for adolescents with TMD in relation to: depression (p=5.6∙10-11), quality of life (p=4.3∙10-12), sleep quality (p=5.0∙10-10), and somnolence (p=0.0002). From the correlation matrix, it was observed that all correlations were significantly positive and moderate. Conclusions: Adolescents with a diagnosis of TMD presented an increase of depression and somnolence, as well as impairment of sleep quality and quality of life, and these same variables can influence on the onset of TMD.
Published: 2021
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16. Improving the admission temperatures of preterm infants in the neonatal unit

Author: Angela Cavallaro and Amy Keir
Subjects: medicine.medical_specialty, Obstetrics, business.industry, Infant, Newborn, Temperature, Health services research, Infant, Gestational Age, Infant, Premature, Diseases, Body Temperature, Unit (housing), Intensive Care Units, Neonatal, Pediatrics, Perinatology and Child Health, medicine, Humans, Gestation, Neonatology, business, Infant, Premature
Abstract: Use of plan-do-study-act cycles to increase the proportion of preterm infants born at
Published: 2021
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17. Fetal MRI mediastinal shift angle and respiratory and cardiovascular pharmacological support in newborns with congenital diaphragmatic hernia

Author: Mariarosa Colnaghi, Francesco Macchini, Nicola Persico, Fabio Mosca, Stefano Ghirardello, Ilaria Amodeo, Giulia Corsani, Giacomo Cavallaro, Valentina Condò, Nicola Pesenti, Irene Borzani, and Genny Raffaeli
Subjects: Mechanical ventilation, medicine.medical_specialty, Lung, Sildenafil, business.industry, medicine.medical_treatment, Mediastinal Shift, Congenital diaphragmatic hernia, medicine.disease, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Internal medicine, Pediatrics, Perinatology and Child Health, medicine, Cardiology, Milrinone, Dobutamine, Respiratory system, business, medicine.drug
Abstract: In newborns with congenital diaphragmatic hernia (CDH), the mediastinal shift caused by the herniated organs negatively affects lung development. Assessment of the fetal magnetic resonance imaging (MRI) mediastinal shift angle (MSA) was shown to have an inverse correlation with the total fetal lung volume (TFLV), being associated with neonatal survival. However, a possible association with postnatal morbidity has never been investigated. We hypothesize that the degree of the mediastinal shift could be associated with higher respiratory and cardiocirculatory impairment, requiring intensive treatments and extended hospitalization in survivors. We retrospectively consider a cohort of isolated, left-sided CDH, for whom we calculated the MSA and the observed/expected (O/E) TFLV at fetal MRI. We performed a data collection regarding inotropic or vasoactive support, treatment with pulmonary vasodilators, mechanical ventilation, and length of stay. General linear models were performed. The MSA and O/E TFLV were inversely correlated (Pearson’s coefficient − 0.65, p < 0.001), and deceased patients showed higher MSA values then survivors (p = 0.011). Among survivors, an increase in MSA was associated with longer pharmacological treatments (dobutamine: p = 0.016; dopamine: p = 0.049; hydrocortisone: p = 0.003; nitric oxide: p = 0.002; sildenafil: p = 0.039; milrinone: p = 0.039; oxygen: p = 0.066), and mechanical ventilation (p = 0.005), with an increasing trend in the length of hospitalization (p = 0.089). Conclusion: The MSA indirectly reflects lung hypoplasia and is associated with a higher neonatal intensity of cares. However, further studies are needed to consolidate the results. Trial registration: The study is an exploratory post hoc analysis of the registered NeoAPACHE protocol at ClinicalTrials.gov with the identifier NCT04396028.
Published: 2021
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18. Parent Training and Therapy in Children with Autism

Author: Alessandro Frolli, Francesca Di Carmine, Giulio Corrivetti, Antonia Bosco, Antonella Cavallaro, Maria Carla Ricci, Agnese Lombardi, and Luana Sergi
Subjects: early social communication scales, Joint attention, applied behavior analysis, medicine.medical_treatment, autism, 050108 psychoanalysis, Pediatrics, Article, RJ1-570, Developmental psychology, Theory of mind, mentalization, Medicine, 0501 psychology and cognitive sciences, Emotional expression, Applied behavior analysis, joint attention, business.industry, 05 social sciences, medicine.disease, reflective function, Mentalization, Autism spectrum disorder, parent training, Parent training, Autism, business, 050104 developmental & child psychology
Abstract: With the introduction of the Diagnostic and Statistical Manual of Mental Disorders-5th ed. (DSM-5) autism spectrum disorders (ASD) fall into the category of neurodevelopmental disorders. ASD is characterized by the inhibitory mechanisms responsible for social adaptation and emotional expression being underdeveloped, causing a child’s recognition and understanding of emotions to be impaired. Our study hypothesizes that early intervention using behavioral interventions such as Applied Behavior Analysis (ABA) and reflexive functions (RF) training on parents can improve the development of joint attention (JA), a cognitive precursor to the theory of mind (ToM) and mentalization processes. We considered a sample of 84 children aged between 20 and 30 months who had received a diagnosis of risk of autism spectrum disorder (level 1). The sample was divided into two groups of 42 subjects, in the first group we carried out a weekly behavioral parent training (PT) based only on ABA principles, while in the second group we carried out a weekly PT aimed at improving reflective functions and parental awareness according to a model inspired by the model based on emotional mirroring and mentalization of Fonagy. Our study shows that parents who are able to make sense of both their own mental state and that of their child can serve as a protective factor for the child’s development even in atypical developmental situations such as in ASD.
Published: 2021

19. Patients Undergoing Ileoanal Pouch Surgery Experience a Constellation of Symptoms and Consequences Representing a Unique Syndrome

Author: Nimalan Jeganathan, Paula Denoya, Paul M Cavallaro, Mantaj S. Brar, Nicola S Fearnhead, Samantha Hendren, Beth-Anne Norton, Thomas E. Cataldo, Karen Zaghiyan, Stefan D. Holubar, Pär Myrelid, Rasheed Clarke, Krisztina B Gecse, Ian P. Bissett, Steven D. Wexner, Liliana Bordeianou, Amber Lorraine Elder, Lauren R. Wilson, Gastroenterology and Hepatology, and AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
Subjects: medicine.medical_specialty, Delphi Technique, Inflammatory bowel disease, Delphi method, MEDLINE, Colonic Pouches, Article, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Crohn Disease, Quality of life, Ileoanal pouch, Humans, Medicine, Patient Reported Outcome Measures, Patient participation, Patient reported outcomes, computer.programming_language, Patient Care Team, Gynecology, ileoanal pouch, inflammatory bowel disease, patient reported outcomes, ulcerative colitis, business.industry, Kirurgi, Proctocolectomy, Restorative, Gastroenterology, Pouch surgery, Recovery of Function, Syndrome, General Medicine, Focus Groups, Focus group, Surgery, Ulcerative colitis, 030220 oncology & carcinogenesis, Quality of Life, Colitis, Ulcerative, 030211 gastroenterology & hepatology, Patient Participation, Pouch, business, computer, Delphi
Abstract: Background Functional outcomes after ileoanal pouch creation have been studied; however, there is great variability in how relevant outcomes are defined and reported. More importantly, the perspective of patients has not been represented in deciding which outcomes should be the focus of research. Objective The primary aim was to create a patient-centered definition of core symptoms that should be included in future studies of pouch function. Design This was a Delphi consensus study. Setting Three rounds of surveys were used to select high-priority items. Survey voting was followed by a series of online patient consultation meetings used to clarify voting trends. A final online consensus meeting with representation from all 3 expert panels was held to finalize a consensus statement. Patients Expert stakeholders were chosen to correlate with the clinical scenario of the multidisciplinary team that cares for pouch patients, including patients, colorectal surgeons, and gastroenterologists or other clinicians. Main outcome measures A consensus statement was the main outcome. Results patients, 62 colorectal surgeons, and 48 gastroenterologists or nurse specialists completed all 3 Delphi rounds. Fifty-three patients participated in online focus groups. One hundred sixty-one stakeholders participated in the final consensus meeting. On conclusion of the consensus meeting, 7 bowel symptoms and 7 consequences of undergoing ileoanal pouch surgery were included in the final consensus statement. Limitations The study was limited by online recruitment bias. Conclusions This study is the first to identify key functional outcomes after pouch surgery with direct input from a large panel of ileoanal pouch patients. The inclusion of patients in all stages of the consensus process allowed for a true patient-centered approach in defining the core domains that should be focused on in future studies of pouch function. See Video Abstract at http://links.lww.com/DCR/B571. Los pacientes sometidos a ciruga de reservorio ileoanal experimentan una constelacin de sntomas y consecuencias que representan un sndrome unico Un Informe de los Resultados Reportados por los Pacientes Posterior a la Cirugia de Reservorio (PROPS) Estudio de Consenso DelphiANTECEDENTES:Los resultados funcionales despues de la creacion del reservorio ileoanal han sido estudiados; sin embargo, existe una gran variabilidad en la forma en que se definen y reportan los resultados relevantes. Mas importante aun, la perspectiva de los pacientes no se ha representado a la hora de decidir que resultados deberian ser el foco de investigacion.OBJETIVO:El objetivo principal era crear en el paciente una definicion centrada de los sintomas principales que deberia incluirse en los estudios futuros de la funcion del reservorio.DISENO:Estudio de consenso Delphi.ENTORNO CLINICO:Se emplearon tres rondas de encuestas para seleccionar elementos de alta prioridad. La votacion de la encuesta fue seguida por una serie de reuniones de consulta de pacientes en linea que se utilizan para aclarar las tendencias de votacion. Se realizo una reunion de consenso final en linea con representacion de los tres paneles de expertos para finalizar una declaracion de consenso.PACIENTES:Se eligieron partes interesadas expertas para correlacionar con el escenario clinico del equipo multidisciplinario que atiende a los pacientes con reservorio: pacientes, cirujanos colorrectales, gastroenterologos / otros medicos.PRINCIPALES MEDIDAS DE VALORACION:Declaracion de consenso.RESULTADOS:Ciento noventa y cinco pacientes, 62 cirujanos colorrectales y 48 gastroenterologos / enfermeras especialistas completaron las tres rondas Delphi. 53 pacientes participaron en grupos focales en linea. 161 interesados participaron en la reunion de consenso final. Al concluir la reunion de consenso, siete sintomas intestinales y siete consecuencias de someterse a una cirugia de reservorio ileoanal se incluyeron en la declaracion de consenso final.LIMITACIONES:Sesgo de reclutamiento en linea.CONCLUSIONES:Este estudio es el primero en identificar resultados funcionales claves despues de la cirugia de reservorio con informacion directa de un gran panel de pacientes con reservorio ileoanal. La inclusion de pacientes en todas las etapas del proceso de consenso permitio un verdadero enfoque centrado en el paciente para definir los dominios principales en los que deberia centrarse los estudios futuros de la funcion del reservorio. Consulte Video Resumen en http://links.lww.com/DCR/B571.
Published: 2021
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20. Cerebellar amelanotic melanoma can mimic cerebellar abscess in a pediatric case of neurocutaneous melanosis

Author: Sergio Vinci, Alessandra Coglitore, Karol Galletta, Marco Cavallaro, Enricomaria Mormina, Francesca Granata, Carmela Visalli, and Agostino Tessitore
Subjects: Pathology, medicine.medical_specialty, Medicine (General), Neurology, Case Report, Case Reports, 030204 cardiovascular system & hematology, paediatrics, 03 medical and health sciences, 0302 clinical medicine, R5-920, Phakomatosis, adolescent medicine, neurology, medicine, Amelanotic melanoma, business.industry, General Medicine, medicine.disease, Neurocutaneous melanosis, 030220 oncology & carcinogenesis, Cerebellar abscess, Medicine, Differential diagnosis, business
Abstract: Neurocutaneous melanosis (NCM) is a rare phakomatosis that may be associated with intracerebral masses. The differential diagnosis of intracerebral masses in NCM is often challenging and should include pigmented and nonpigmented lesions.
Published: 2021

21. Changes over time in HIV testing and counselling uptake and associated factors among youth in Zambia: a cross-sectional analysis of demographic and health surveys from 2007 to 2018

Author: Maurice Mubuyaeta Musheke, Nurilign Ahmed, Mitsuaki Matsui, Francesca L. Cavallaro, and Aimé Bitakuya Heri
Subjects: Adult, Counseling, Male, medicine.medical_specialty, Multivariate analysis, 90–90-90, Youth, Adolescent, Cross-sectional study, Zambia, HIV Infections, 030312 virology, Demographic health survey, Logistic regression, Adolescents, Odds, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Acquired immunodeficiency syndrome (AIDS), Pregnancy, Epidemiology, Humans, Mass Screening, Medicine, 030212 general & internal medicine, Demography, 0303 health sciences, Sub-Saharan Africa, business.industry, Public health, lcsh:Public aspects of medicine, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, HTC, medicine.disease, Health Surveys, HIV testing, Cross-Sectional Studies, HIV/AIDS, Female, Biostatistics, business, Research Article
Abstract: Introduction: Zambia is among the countries with the highest HIV burden and where youth remain disproportionally affected. Access to HIV testing and counselling (HTC) is a crucial step to ensure the reduction of HIV transmission. This study examines the changes that occurred between 2007 and 2018 in access to HTC, inequities in testing uptake, and determinants of HTC uptake among youth. Methods: We carried out repeated cross-sectional analyses using three Zambian Demographic and Health Surveys (2007, 2013–14, and 2018). We calculated the percentage of women and men ages 15–24 years old who were tested for HIV in the last 12 months. We analysed inequity in HTC coverage using indicators of absolute inequality. We performed bivariate and multivariate logistic regression analyses to identify predictors of HTC uptake in the last 12 months. Results: HIV testing uptake increased between 2007 and 2018, from 45 to 92% among pregnant women, 10 to 58% among non-pregnant women, and from 10 to 49% among men. By 2018 roughly 60% of youth tested in the past 12 months used a government health centre. Mobile clinics were the second most common source reaching up to 32% among adolescent boys by 2018. Multivariate analysis conducted among men and non-pregnant women showed higher odds of testing among 20–24 year-olds than adolescents (aOR = 1.55 [95%CI:1.30–1.84], among men; and aOR = 1.74 [1.40–2.15] among women). Among men, being circumcised (aOR = 1.57 [1.32–1.88]) and in a union (aOR = 2.44 [1.83–3.25]) were associated with increased odds of testing. For women greater odds of testing were associated with higher levels of education (aOR = 6.97 [2.82–17.19]). Education-based inequity was considerably widened among women than men by 2018. Conclusion: HTC uptake among Zambian youth improved considerably by 2018 and reached 65 and 49% tested in the last 12 months for women and men, respectively. However, achieving the goal of 95% envisioned by 2020 will require sustaining the success gained through government health centres, and scaling up the community-led approaches that have proven acceptable and effective in reaching young men and adolescent girls who are less easy to reach through the government facilities., BMC Public Health, 21, art. no. 456; 2021
Published: 2021

22. Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

Author: Bracale, U., Podda, Maria Vittoria, Castiglioni, S., Peltrini, R., Sartori, Alessandra, Arezzo, A., Corcione, F., Agresta, F., Antonucci, A., Zanframundo, C., Cavallo, F., Mazzarolo, G., Agrusa, A., Di Buono, G., Aldrighetti, L., Fiorentini, G., Lucianetti, A., Magnone, S., Alfieri, Sergio, Rosa, Fausto, Altomare, D. F., Picciariello, A., Parisi, Carmelo Maria Antonio, Di Cintio, A., Amisano, M. F., Cravero, F., Ammendola, M., Ammerata, G., Anastasi, A., Canonico, G., Gattolin, A., Travaglio, E., De Palma, M., Angelini, P., Galante, F., Benevento, A., Rausei, S., Serao, A., Abbatini, F., Annecchiarico, M., Varricchio, A., Annessi, V., Tumiati, D., Annicchiarico, A., Mirabella, A., Marino, M. V., Spinelli, A., Braun, A., Santi, H. T., Romano, L., Antoniutti, M., Armellino, M. F., Argenio, G., Verzelli, A., Budassi, A., Baiocchi, G., Alfano, M. S., Balani, A., Barone, M., Baldazzi, G., Cassini, D., Canger, R. C. B., Zabbialini, G., Belli, Andrea, Izzo, Filippo, Bertolino, F., Brunetti, Maria Mercede, Bianco, Flaviana, Cappiello, A., Boccia, L., Boffi, B., Perna, Francesco, Bonilauri, S., Frazzetta, G., Bordoni, P., Fleres, F., Borghi, F., Giraudo, G., Bottino, V., Canfora, A., Piccoli, F. B., Calligaris, L., Nipote, B., Nasti, A. G., Bufalari, A., Bettarini, F., Buononato, M., Greco, M., Calo, P. G., Medas, F., Cardamone, E., Castaldo, P., Carlini, M., Spoletini, D., De Nisco, C., Pulighe, F., Feo, C. V., Fabbri, N., Antropoli, C., Foroni, F., Carnazza, M., Ragazzi, S., Cassinotti, E., Boni, L., Catena, F., Giuffrida, M., Perrone, Giuseppe, Ccotsoglou, C., Granieri, S., Ceccarelli, G., Bugiantella, W., Cedolini, C., Seriau, L., Cesari, Matteo, Contine, A., Chiara, Osvaldo, Cimbanassi, S., Cocozza, E., Berselli, M., Fantini, C., Costi, R., Casali, L., Morini, A., Crafa, F., Vanela, S., Curro, G., Orsini, V., Da Lio, C., Biral, Maria Francesca, Danelli, P., Guerci, C., Scala, D., Marino, Giuseppe, De Carlis, L., Lauterio, A., De Giorgi, D., Sciannamea, G., De Manzini, N., Losurdo, P., Sangiuliano, N., Degiuli, M., Caterina, F., Del Rio, P., Bonati, E., Di Lernia, S., Ardizzone, M. V. R., Di Saverio, S., Franchi, C., Di Venere, B., Miglio, R., Cuccurullo, D., Sagnelli, C., Docimo, L., Tolone, S., Longoni, M., Faillace, G., Rondelli, F., Pennella, F. P., Colucci, V., Carfora, T., Muttillo, I. A., Picardi, B., Stefano, R., Campagnacci, R., Maurizi, A., Tricarico, F., Montagna, M., Amedeo, E., Scollica, M. C., Lauro, E., Laterza, E., Molinari, E., Berta, G., Bono, D., Fabozzi, Simone Michele, Romano, M., Facci, E., Parini, D., Farfaglia, R., Arizzi, V., Farsi, M., Miranda, E., Fei, L., Flavio, G., Pirozzi, F., Sciuto, A., Ferrero, A., Palisi, M., Filauro, M., Barberis, A., Azzinnaro, A., Fiscon, V., Vigna, S., D'Ambra, M., Pontecorvi, E., Anania, G., Bombardini, C., Galizia, G., Auricchio, Anna Maria, Cardella, F., Genna, M., Gentilli, S., Herald, N., Castagnoli, G., Bartoli, A., Gianotti, L., Garancini, M., Bellanova, G., Palazzo, P., De Palma, G., Milone, Maria, Ferrari, G., Magistro, C., Giuliani, Antonio, Di Natale, Maria Grazia, Brisinda, Giuseppe, Cavallaro, G., Sammarco, G., Gallo, Giuseppe, Goletti, O., Macchini, D., Greco, Viviana, Amoroso, V., Guercioni, G., Benedetti, M., Guzzo, G., Pata, F., Scandroglio, I., Roscio, F., Jovine, E., Lombardi, Roberto, La Rocca, F., Di Capua, F., Lanci, C., Leli, R., Borasi, A., Lepiane, P., Balla, A., Liberatore, E., Morelli, L., Di Franco, G., Lucchi, A., Vittori, L., Bonavina, L., Asti, Emilio Fabrizio, Maggioni, D., Martino, G., Manca, Gavina, Delvecchio, A., Tedesco, M., Gambardella, D., Marafioti, S., De Marco, M. L., Guicciardi, M. A., Motta, M., Calgaro, M., Adamo, V., Guerrieri, Maria Chiara, Coletta, P., Ortenzi, M., Martines, G., Lantone, G., Martinotti, M., Fassardi, G., Castriconi, M., Squillante, S., De Luca, M., Pavanello, M., Di Marco, C., Ronconi, M., Casiraghi, Maria Stella, Mazzaferro, V., Battiston, C., Perrotta, M., Ripa, C., Giancarlo, M., Panizzo, V., Millo, P., Contul, R. B., Ferraro, V., Molino, C., Crolla, E., Moretto, G., Bacchion, M., Morino, M., Allaix, M. E., Motterlini, E., Petracca, Martina, Muratore, A., Musella, Martina, Vitiello, A., Nardo, B., Crocco, V., Navarra, G., Lazzara, S., Navarra, G. G., Cuoghi, M., Olmi, S., Oldani, Alberto, Uccelli, M., Opocher, E., Giovenzana, M., De Paolis, P., Santarelli, M., Delrio, P., Carbone, F., Bianchi, P. P. G., Formisano, Capelli, P., Baldini, E., Festa, P., Mottola, Armando, Merola, G., Perrotta, N., Celiento, M., Personnettaz, E., Muzio, S., Petitti, T., Melchiorre, A., Piccoli, M., Pecchini, F., Frontali, A., Maffioli, A., Maida, P., Tammaro, P., Pignata, G., Andreuccetti, J., Pilone, V., Renzulli, M., Pintaldi, S., Ceretti, A. P., Mariani, N. M., Pisanu, A., Polastri, R., Maiello, F., Porcu, A., Perra, T., Mucilli, F., Troisi, R., Montalti, R., Scognamillo, F., Delogu, D., Galleano, R., Malerba, M., Salfi, R., Pisano, M., Sechi, R., Cillara, N., Ramuscello, S., De Leo, E., Restini, E., Tumolo, R., Cianci, P., Capuzzolo, S., Rizzo, M., Recordare, A., Santoro, Roberto, Amodio, P. M., Rocca, A., Cecere, G., Romito, R., Portigliotti, L., Rosati, R., Elmore, U., Russello, D., Latteri, S., Costarella, S. M., Massa, S., Capasso, L., Santangelo, M., Sodo, M., Sarro, G., Rivolta, U., Scabini, S., Pertile, D., Selvaggi, F., Rossi, S., Pellino, G., Sganga, Gabriele, Fransvea, P., Testa, S., De Rosa, Maria Cristina, Siquini, W., Trana, C., Solej, M., Bolzon, S., Guerra, Eliana, Stella, M., Ferrara, F., Stipa, F., Stringhi, E., Celotti, A., Taglietti, L., Del Giudice, R., Talarico, C. A., Ruggiero, Miriam, Tirone, G., Romario, U. F., Petz, W., Caracino, V., Rossetti, V., Verza, L. A., Vescovi, L., Marini, M., Vettoretto, N., Botteri, E., Vincenti, L., Giannandrea, G., Viora, T., Maganuco, L., Veronesi, P., Zani, B., Zanus, G., Brizzolari, M., Zanzi, F., Guariniello, A., Zappa, M. A., Galfrascoli, E., Zonta, S., Oragano, L., Zuliani, W., Chiari, D., Bracale, Umberto, Podda, Mauro, Castiglioni, Simone, Peltrini, Roberto, Sartori, Alberto, Arezzo, Alberto, Corcione, Francesco, Agresta, Ferdinando, Rosati, Riccardo, Umberto, Bracale, Mauro, Podda, Simone, Castiglioni, Roberto, Peltrini, Alberto, Sartori, Alberto, Arezzo, Francesco, Corcione, Ferdinando, Agresta, CLOUD-19 Collaborative Group Adelmo Antonucci, Claudia, Zanframundo, Fabio, Cavallo, Giorgio, Mazzarolo, Antonio, Agrusa, Giuseppe Di Buono, Luca, Aldrighetti, Guido, Fiorentini, Alessandro, Lucianetti, Stefano, Magnone, Sergio, Alfieri, Fausto, Rosa, Altomare, Donato F., Arcangelo, Picciariello, Amilcare, Parisi, Antonio Di Cintio, Marco Francesco Amisano, Francesca, Cravero, Michele, Ammendola, Giorgio, Ammerata, Alessandro, Anastasi, Giuseppe, Canonico, Andra, Gattolin, Elisabetta, Travaglio, Andrea, Sartori, Massimiliano De Palma, Pierluigi, Angelini, Francesco, Galante, Angelo, Benevento, Stefano, Rausei, Angelo, Serao, Francesca, Abbatini, Mario, Annecchiarico, Antonio, Varricchio, Valerio, Annessi, David, Tumiati, Alfredo, Annicchiarico, Antonello, Mirabella, Marino, Marco V., Antonino, Spinelli, Antonio, Braun, Hong Tham Santi, Lucia, Romano, Michele, Antoniutti, Mariano Fortunato Armellino, Giulio, Argenio, Augusto, Verzelli, Andrea, Budassi, Gianluca, Baiocchi, Marie Sophie Alfano, Alessandro, Balani, Marco, Barone, Gianandrea, Baldazzi, Diletta, Cassini, Ruben Carlo Balzarotti Canger, Gianpietro, Zabbialini, Andrea, Belli, Francesco, Izzo, Franco, Bertolino, Marco, Brunetti, Francesco, Bianco, Antonio, Cappiello, Luigi, Boccia, Bernardo, Boffi, Federico, Perna, Stefano, Bonilauri, Giuseppe, Frazzetta, Pierpaolo, Bordoni, Francesco, Flere, Felice, Borghi, Giorgio, Giraudo, Vincenzo, Bottino, Alfonso, Canfora, Fabrizio Briganti Piccoli, Luca, Calligari, Bruno, Nipote, Aniello Gennaro Nasti, Andrea, Bufalari, Francesca, Bettarini, Massimo, Buononato, Marco, Greco, Pietro Giorgio Calò, Fabio, Meda, Eugenia, Cardamone, Pasquale, Castaldo, Massimo, Carlini, Domenico, Spoletini, Carlo De Nisco, Fabio, Pulighe, Feo, Carlo V., Nicolò, Fabbri, Carmine, Antropoli, Fabrizio, Foroni, Maurizio, Carnazza, Salvatore, Ragazzi, Elisa, Cassinotti, Luigi, Boni, Fausto, Catena, Mario, Giuffrida, Gennaro, Perrone, Christian, Ccotsoglou, Stefano, Granieri, Graziano, Ceccarelli, Walter, Bugiantella, Carla, Cedolini, Luca, Seriau, Maurizio, Cesari, Alessandro, Contine, Osvaldo, Chiara, Stefania, Cimbanassi, Eugenio, Cocozza, Mattia, Berselli, Corrado, Fantini, Renato, Costi, Lorenzo, Casali, Andrea, Morini, Francesco, Crafa, Serafino, Vanela, Giuseppe, Currò, Vincenzo, Orsini, Corrado Da Lio, Mario, Biral, Piergiorgio, Danelli, Claudio, Guerci, Dario, Scala, Graziella, Marino, Luciano De Carlis, Andrea, Lauterio, Donato De Giorgi, Gianluca, Sciannamea, Nicolo De Manzini, Pasquale, Losurdo, Maurizio De Palma, Nicola, Sangiuliano, Maurizio, Degiuli, Franco, Caterina, Paolo Del Rio, Elena, Bonati, Stefano Di Lernia, Marco Vittorio Rossi Ardizzone, Salomone Di Saverio, Caterina, Franchi, Beatrice Di Venere, Rosanna, Miglio, Diego, Cuccurullo, Carlo, Sagnelli, Docimo, Ludovico, Tolone, Salvatore, Mauro, Longoni, Giuseppe, Faillace, Fabio, Rondelli, Francesca Pennetti Pennella, Vincenzo, Colucci, Teresa, Carfora, Irnerio Angelo Muttillo, Biagio, Picardi, Rossi, Stefano, Roberto, Campagnacci, Angela, Maurizi, Fausto, Tricarico, Marco, Montagna, Elio, Amedeo, Scollica, Michela C., Enrico, Lauro, Ernesto, Laterza, Enrico, Molinari, Berta, G., Dario, Bono, Massimiliano, Fabozzi, Mafalda, Romano, Enzo, Facci, Dario, Parini, Roberto, Farfaglia, Valeria, Arizzi, Marco, Farsi, Egidio, Miranda, Fei, Landino, Giordano, Flavio, Felice, Pirozzi, Antonio, Sciuto, Alessandro, Ferrero, Marco, Palisi, Marco, Filauro, Andrea, Barberi, Antonio, Azzinnaro, Valentino, Fiscon, Silvia, Vigna, Michele, D’Ambra, Emanuele, Pontecorvi, Gabriele, Anania, Cristina, Bombardini, Galizia, Gennaro, Auricchio, Annamaria, Cardella, Francesca, Michele, Genna, Sergio, Gentilli, Nikaj, Herald, Giampaolo, Castagnoli, Alberto, Bartoli, Luca, Gianotti, Mattia, Garancini, Giovanni, Bellanova, Paola, Palazzo, Giovanni De Palma, Marco, Milone, Giovanni, Ferrari, Carmelo, Magistro, Antonio, Giuliani, Giuseppe Di Natale, Giuseppe, Brisinda, Giuseppe, Cavallaro, Giuseppe, Sammarco, Gaetano, Gallo, Orlando, Goletti, Daniele, Macchini, Vincenzo, Greco, Vincenzo, Amoroso, Gianluca, Guercioni, Michele, Benedetti, Guglielmo, Guzzo, Francesco, Pata, Ildo, Scandroglio, Francesco, Roscio, Elio, Jovine, Raffaele, Lombardi, Francesco La Rocca, Francesca Di Capua, Carmine, Lanci, Renzo, Leli, Andrea, Borasi, Pasquale, Lepiane, Andrea, Balla, Edoardo, Liberatore, Luca, Morelli, Gregorio Di Franco, Andrea, Lucchi, Laura, Vittori, Luigi, Bonavina, Emanuele, Asti, Dario, Maggioni, Gerosa, Martino, Giuseppe, Manca, Antonella, Delvecchio, Manfredo, Tedesco, Denise, Gambardella, Salvatore, Marafioti, Maria Luisa De Marco, Marco Azzola Guicciardi, Massimo, Motta, Marco, Calgaro, Vincenzo, Adamo, Mario, Guerrieri, Pietro, Coletta, Monica, Ortenzi, Gennaro, Martine, Giuliano, Lantone, Mario, Martinotti, Giuseppe, Fassardi, Maurizio, Castriconi, Simone, Squillante, Maurizio De Luca, Maurizio, Pavanello, Carlo Di Marco, Maurizio, Ronconi, Silvia, Casiraghi, Vincenzo, Mazzaferro, Carlo, Battiston, Michele, Perrotta, Carmine, Ripa, Micheletto, Giancarlo, Valerio, Panizzo, Paolo, Millo, Riccardo Brachet Contul, Valentina, Ferraro, Carlo, Molino, Enrico, Crolla, Gianluigi, Moretto, Matilde, Bacchion, Mario, Morino, Marco Ettore Allaix, Enrico, Motterlini, Michele, Petracca, Andrea, Muratore, Mario, Musella, Antonio, Vitiello, Bruno, Nardo, Veronica, Crocco, Giuseppe, Navarra, Salvatore, Lazzara, Giuseppe Giovanni Navarra, Manuela, Cuoghi, Stefano, Olmi, Alberto, Oldani, Matteo, Uccelli, Enrico, Opocher, Marco, Giovenzana, Paolo De Paolis, Mauro, Santarelli, Paolo, Delrio, Fabio, Carbone, Paolo Pietro Giampaolo Bianchi, Formisano, Patrizio, Capelli, Edoardo, Baldini, Patrizio, Festa, Arianna, Mottola, Giovanni, Merola, Nicola, Perrotta, Marta, Celiento, Eraldo, Personnettaz, Stefania, Muzio, Tommaso, Petitti, Antonietta, Melchiorre, Micaela, Piccoli, Francesca, Pecchini, Alice, Frontali, Anna, Maffioli, Pietro, Maida, Pasquale, Tammaro, Giusto, Pignata, Jacopo, Andreuccetti, Vincenzo, Pilone, Michele, Renzulli, Salvatore, Pintaldi, Andrea Pisani Ceretti, Nicolò Maria Mariani, Adolfo, Pisanu, Roberto, Polastri, Fabio, Maiello, Alberto, Porcu, Teresa, Perra, Felice, Mucilli, Mirko, Barone, Roberto, Troisi, Roberto, Montalti, Fabrizio, Scognamillo, Daniele, Delogu, Raffaele, Galleano, Michele, Malerba, Raffaele, Salfi, Marcello, Pisano, Raffaele, Sechi, Nicola, Cillara, Salvatore, Ramuscello, Eugenio De Leo, Enrico, Restini, Rocco, Tumolo, Pasquale, Cianci, Sabino, Capuzzolo, Maurizio, Rizzo, Alfonso, Recordare, Roberto, Santoro, Pietro Maria Amodio, Aldo, Rocca, Giuseppe, Cecere, Raffaele, Romito, Luca, Portigliotti, Riccardo, Rosati, Ugo, Elmore, Domenico, Russello, Saverio, Latteri, Salvatore Maria Costarella, Salvatore, Massa, Lorenzo, Capasso, Michele, Santangelo, Maurizio, Sodo, Giuliano, Sarro, Umberto, Rivolta, Stefano, Scabini, Davide, Pertile, Federico, Selvaggi, Selene, Rossi, Selvaggi, Francesco, Pellino, Gianluca, Gabriele, Sganga, Pietro, Fransvea, Silvio, Testa, Clemente De Rosa, Walter, Siquini, Cristian, Tranà, Mario, Solej, Stefano, Bolzon, Enrico, Guerra, Marco, Stella, Francesco, Ferrara, Francesco, Stipa, Enrico, Stringhi, Andrea, Celotti, Lucio, Taglietti, Roberto Del Giudice, Carlo Alessandro Talarico, Michele, Ruggiero, Giuseppe, Tirone, Uberto Fumagalli Romario, Wanda, Petz, Valerio, Caracino, Valentina, Rossetti, Luca Andrea Verza, Lorenzo, Vescovi, Michele, Marini, Nereo, Vettoretto, Emanuele, Botteri, Leonardo, Vincenti, Giusy, Giannandrea, Tiziana, Viora, Lorenzo, Maganuco, Paolo, Veronesi, Bruno, Zani, Giacomo, Zanu, Marco, Brizzolari, Federico, Zanzi, Anna, Guariniello, Marco Antonio Zappa, Elisa, Galfrascoli, Sandro, Zonta, Luigi, Oragano, Walter Zuliani &amp, Damiano, Chiari, de Manzini, Nicolo', Agresta, Ferdinando, Agrusa, Antonino, Di Buono, Giuseppe, Bracale, U., Podda, M., Castiglioni, S., Peltrini, R., Sartori, A., Arezzo, A., Corcione, F., Agresta, F., Antonucci, A., Zanframundo, C., Cavallo, F., Mazzarolo, G., Agrusa, A., Di Buono, G., Aldrighetti, L., Fiorentini, G., Lucianetti, A., Magnone, S., Alfieri, S., Rosa, F., Altomare, D. F., Picciariello, A., Parisi, A., Di Cintio, A., Amisano, M. F., Cravero, F., Ammendola, M., Ammerata, G., Anastasi, A., Canonico, G., Gattolin, A., Travaglio, E., De Palma, M., Angelini, P., Galante, F., Benevento, A., Rausei, S., Serao, A., Abbatini, F., Annecchiarico, M., Varricchio, A., Annessi, V., Tumiati, D., Annicchiarico, A., Mirabella, A., Marino, M. V., Spinelli, A., Braun, A., Santi, H. T., Romano, L., Antoniutti, M., Armellino, M. F., Argenio, G., Verzelli, A., Budassi, A., Baiocchi, G., Alfano, M. S., Balani, A., Barone, M., Baldazzi, G., Cassini, D., Canger, R. C. B., Zabbialini, G., Belli, A., Izzo, F., Bertolino, F., Brunetti, M., Bianco, F., Cappiello, A., Boccia, L., Boffi, B., Perna, F., Bonilauri, S., Frazzetta, G., Bordoni, P., Fleres, F., Borghi, F., Giraudo, G., Bottino, V., Canfora, A., Piccoli, F. B., Calligaris, L., Nipote, B., Nasti, A. G., Bufalari, A., Bettarini, F., Buononato, M., Greco, M., Calo, P. G., Medas, F., Cardamone, E., Castaldo, P., Carlini, M., Spoletini, D., De Nisco, C., Pulighe, F., Feo, C. V., Fabbri, N., Antropoli, C., Foroni, F., Carnazza, M., Ragazzi, S., Cassinotti, E., Boni, L., Catena, F., Giuffrida, M., Perrone, G., Ccotsoglou, C., Granieri, S., Ceccarelli, G., Bugiantella, W., Cedolini, C., Seriau, L., Cesari, M., Contine, A., Chiara, O., Cimbanassi, S., Cocozza, E., Berselli, M., Fantini, C., Costi, R., Casali, L., Morini, A., Crafa, F., Vanela, S., Curro, G., Orsini, V., Da Lio, C., Biral, M., Danelli, P., Guerci, C., Scala, D., Marino, G., De Carlis, L., Lauterio, A., De Giorgi, D., Sciannamea, G., De Manzini, N., Losurdo, P., Sangiuliano, N., Degiuli, M., Caterina, F., Del Rio, P., Bonati, E., Di Lernia, S., Ardizzone, M. V. R., Di Saverio, S., Franchi, C., Di Venere, B., Miglio, R., Cuccurullo, D., Sagnelli, C., Docimo, L., Tolone, S., Longoni, M., Faillace, G., Rondelli, F., Pennella, F. P., Colucci, V., Carfora, T., Muttillo, I. A., Picardi, B., Stefano, R., Campagnacci, R., Maurizi, A., Tricarico, F., Montagna, M., Amedeo, E., Scollica, M. C., Lauro, E., Laterza, E., Molinari, E., Bono, D., Fabozzi, M., Romano, M., Facci, E., Parini, D., Farfaglia, R., Arizzi, V., Farsi, M., Miranda, E., Fei, L., Flavio, G., Pirozzi, F., Sciuto, A., Ferrero, A., Palisi, M., Filauro, M., Barberis, A., Azzinnaro, A., Fiscon, V., Vigna, S., D'Ambra, M., Pontecorvi, E., Anania, G., Bombardini, C., Galizia, G., Auricchio, A., Cardella, F., Genna, M., Gentilli, S., Herald, N., Castagnoli, G., Bartoli, A., Gianotti, L., Garancini, M., Bellanova, G., Palazzo, P., De Palma, G., Milone, M., Ferrari, G., Magistro, C., Giuliani, A., Di Natale, G., Brisinda, G., Cavallaro, G., Sammarco, G., Gallo, G., Goletti, O., Macchini, D., Greco, V., Amoroso, V., Guercioni, G., Benedetti, M., Guzzo, G., Pata, F., Scandroglio, I., Roscio, F., Jovine, E., Lombardi, R., La Rocca, F., Di Capua, F., Lanci, C., Leli, R., Borasi, A., Lepiane, P., Balla, A., Liberatore, E., Morelli, L., Di Franco, G., Lucchi, A., Vittori, L., Bonavina, L., Asti, E., Maggioni, D., Martino, G., Manca, G., Delvecchio, A., Tedesco, M., Gambardella, D., Marafioti, S., De Marco, M. L., Guicciardi, M. A., Motta, M., Calgaro, M., Adamo, V., Guerrieri, M., Coletta, P., Ortenzi, M., Martines, G., Lantone, G., Martinotti, M., Fassardi, G., Castriconi, M., Squillante, S., De Luca, M., Pavanello, M., Di Marco, C., Ronconi, M., Casiraghi, S., Mazzaferro, V., Battiston, C., Perrotta, M., Ripa, C., Giancarlo, M., Panizzo, V., Millo, P., Contul, R. B., Ferraro, V., Molino, C., Crolla, E., Moretto, G., Bacchion, M., Morino, M., Allaix, M. E., Motterlini, E., Petracca, M., Muratore, A., Musella, M., Vitiello, A., Nardo, B., Crocco, V., Navarra, G., Lazzara, S., Navarra, G. G., Cuoghi, M., Olmi, S., Oldani, A., Uccelli, M., Opocher, E., Giovenzana, M., De Paolis, P., Santarelli, M., Delrio, P., Carbone, F., Bianchi, P. P. G., Capelli, P., Baldini, E., Festa, P., Mottola, A., Merola, G., Perrotta, N., Celiento, M., Personnettaz, E., Muzio, S., Petitti, T., Melchiorre, A., Piccoli, M., Pecchini, F., Frontali, A., Maffioli, A., Maida, P., Tammaro, P., Pignata, G., Andreuccetti, J., Pilone, V., Renzulli, M., Pintaldi, S., Ceretti, A. P., Mariani, N. M., Pisanu, A., Polastri, R., Maiello, F., Porcu, A., Perra, T., Mucilli, F., Troisi, R., Montalti, R., Scognamillo, F., Delogu, D., Galleano, R., Malerba, M., Salfi, R., Pisano, M., Sechi, R., Cillara, N., Ramuscello, S., De Leo, E., Restini, E., Tumolo, R., Cianci, P., Capuzzolo, S., Rizzo, M., Recordare, A., Santoro, R., Amodio, P. M., Rocca, A., Cecere, G., Romito, R., Portigliotti, L., Rosati, R., Elmore, U., Russello, D., Latteri, S., Costarella, S. M., Massa, S., Capasso, L., Santangelo, M., Sodo, M., Sarro, G., Rivolta, U., Scabini, S., Pertile, D., Selvaggi, F., Rossi, S., Pellino, G., Sganga, G., Fransvea, P., Testa, S., De Rosa, C., Siquini, W., Trana, C., Solej, M., Bolzon, S., Guerra, E., Stella, M., Ferrara, F., Stipa, F., Stringhi, E., Celotti, A., Taglietti, L., Del Giudice, R., Talarico, C. A., Ruggiero, M., Tirone, G., Romario, U. F., Petz, W., Caracino, V., Rossetti, V., Verza, L. A., Vescovi, L., Marini, M., Vettoretto, N., Botteri, E., Vincenti, L., Giannandrea, G., Viora, T., Maganuco, L., Veronesi, P., Zani, B., Zanus, G., Brizzolari, M., Zanzi, F., Guariniello, A., Zappa, M. A., Galfrascoli, E., Zonta, S., Oragano, L., Zuliani, W., Chiari, D., Bracale, U, Podda, M, Castiglioni, S, Peltrini, R, Sartori, A, Arezzo, A, Corcione, F, Agresta, F, Antonucci, A, Zanframundo, C, Cavallo, F, Mazzarolo, G, Agrusa, A, Di Buono, G, Aldrighetti, L, Fiorentini, G, Lucianetti, A, Magnone, S, Alfieri, S, Rosa, F, Altomare, D, Picciariello, A, Parisi, A, Di Cintio, A, Amisano, M, Cravero, F, Ammendola, M, Ammerata, G, Anastasi, A, Canonico, G, Gattolin, A, Travaglio, E, De Palma, M, Angelini, P, Galante, F, Benevento, A, Rausei, S, Serao, A, Abbatini, F, Annecchiarico, M, Varricchio, A, Annessi, V, Tumiati, D, Annicchiarico, A, Mirabella, A, Marino, M, Spinelli, A, Braun, A, Santi, H, Romano, L, Antoniutti, M, Armellino, M, Argenio, G, Verzelli, A, Budassi, A, Baiocchi, G, Alfano, M, Balani, A, Barone, M, Baldazzi, G, Cassini, D, Canger, R, Zabbialini, G, Belli, A, Izzo, F, Bertolino, F, Brunetti, M, Bianco, F, Cappiello, A, Boccia, L, Boffi, B, Perna, F, Bonilauri, S, Frazzetta, G, Bordoni, P, Fleres, F, Borghi, F, Giraudo, G, Bottino, V, Canfora, A, Piccoli, F, Calligaris, L, Nipote, B, Nasti, A, Bufalari, A, Bettarini, F, Buononato, M, Greco, M, Calo, P, Medas, F, Cardamone, E, Castaldo, P, Carlini, M, Spoletini, D, De Nisco, C, Pulighe, F, Feo, C, Fabbri, N, Antropoli, C, Foroni, F, Carnazza, M, Ragazzi, S, Cassinotti, E, Boni, L, Catena, F, Giuffrida, M, Perrone, G, Ccotsoglou, C, Granieri, S, Ceccarelli, G, Bugiantella, W, Cedolini, C, Seriau, L, Cesari, M, Contine, A, Chiara, O, Cimbanassi, S, Cocozza, E, Berselli, M, Fantini, C, Costi, R, Casali, L, Morini, A, Crafa, F, Vanela, S, Curro, G, Orsini, V, Da Lio, C, Biral, M, Danelli, P, Guerci, C, Scala, D, Marino, G, De Carlis, L, Lauterio, A, De Giorgi, D, Sciannamea, G, De Manzini, N, Losurdo, P, Sangiuliano, N, Degiuli, M, Caterina, F, Del Rio, P, Bonati, E, Di Lernia, S, Ardizzone, M, Di Saverio, S, Franchi, C, Di Venere, B, Miglio, R, Cuccurullo, D, Sagnelli, C, Docimo, L, Tolone, S, Longoni, M, Faillace, G, Rondelli, F, Pennella, F, Colucci, V, Carfora, T, Muttillo, I, Picardi, B, Stefano, R, Campagnacci, R, Maurizi, A, Tricarico, F, Montagna, M, Amedeo, E, Scollica, M, Lauro, E, Laterza, E, Molinari, E, Berta, G, Bono, D, Fabozzi, M, Romano, M, Facci, E, Parini, D, Farfaglia, R, Arizzi, V, Farsi, M, Miranda, E, Fei, L, Flavio, G, Pirozzi, F, Sciuto, A, Ferrero, A, Palisi, M, Filauro, M, Barberis, A, Azzinnaro, A, Fiscon, V, Vigna, S, D'Ambra, M, Pontecorvi, E, Anania, G, Bombardini, C, Galizia, G, Auricchio, A, Cardella, F, Genna, M, Gentilli, S, Herald, N, Castagnoli, G, Bartoli, A, Gianotti, L, Garancini, M, Bellanova, G, Palazzo, P, De Palma, G, Milone, M, Ferrari, G, Magistro, C, Giuliani, A, Di Natale, G, Brisinda, G, Cavallaro, G, Sammarco, G, Gallo, G, Goletti, O, Macchini, D, Greco, V, Amoroso, V, Guercioni, G, Benedetti, M, Guzzo, G, Pata, F, Scandroglio, I, Roscio, F, Jovine, E, Lombardi, R, La Rocca, F, Di Capua, F, Lanci, C, Leli, R, Borasi, A, Lepiane, P, Balla, A, Liberatore, E, Morelli, L, Di Franco, G, Lucchi, A, Vittori, L, Bonavina, L, Asti, E, Maggioni, D, Martino, G, Manca, G, Delvecchio, A, Tedesco, M, Gambardella, D, Marafioti, S, De Marco, M, Guicciardi, M, Motta, M, Calgaro, M, Adamo, V, Guerrieri, M, Coletta, P, Ortenzi, M, Martines, G, Lantone, G, Martinotti, M, Fassardi, G, Castriconi, M, Squillante, S, De Luca, M, Pavanello, M, Di Marco, C, Ronconi, M, Casiraghi, S, Mazzaferro, V, Battiston, C, Perrotta, M, Ripa, C, Giancarlo, M, Panizzo, V, Millo, P, Contul, R, Ferraro, V, Molino, C, Crolla, E, Moretto, G, Bacchion, M, Morino, M, Allaix, M, Motterlini, E, Petracca, M, Muratore, A, Musella, M, Vitiello, A, Nardo, B, Crocco, V, Navarra, G, Lazzara, S, Cuoghi, M, Olmi, S, Oldani, A, Uccelli, M, Opocher, E, Giovenzana, M, De Paolis, P, Santarelli, M, Delrio, P, Carbone, F, Bianchi, P, Capelli, P, Baldini, E, Festa, P, Mottola, A, Merola, G, Perrotta, N, Celiento, M, Personnettaz, E, Muzio, S, Petitti, T, Melchiorre, A, Piccoli, M, Pecchini, F, Frontali, A, Maffioli, A, Maida, P, Tammaro, P, Pignata, G, Andreuccetti, J, Pilone, V, Renzulli, M, Pintaldi, S, Ceretti, A, Mariani, N, Pisanu, A, Polastri, R, Maiello, F, Porcu, A, Perra, T, Mucilli, F, Troisi, R, Montalti, R, Scognamillo, F, Delogu, D, Galleano, R, Malerba, M, Salfi, R, Pisano, M, Sechi, R, Cillara, N, Ramuscello, S, De Leo, E, Restini, E, Tumolo, R, Cianci, P, Capuzzolo, S, Rizzo, M, Recordare, A, Santoro, R, Amodio, P, Rocca, A, Cecere, G, Romito, R, Portigliotti, L, Rosati, R, Elmore, U, Russello, D, Latteri, S, Costarella, S, Massa, S, Capasso, L, Santangelo, M, Sodo, M, Sarro, G, Rivolta, U, Scabini, S, Pertile, D, Selvaggi, F, Rossi, S, Pellino, G, Sganga, G, Fransvea, P, Testa, S, De Rosa, C, Siquini, W, Trana, C, Solej, M, Bolzon, S, Guerra, E, Stella, M, Ferrara, F, Stipa, F, Stringhi, E, Celotti, A, Taglietti, L, Del Giudice, R, Talarico, C, Ruggiero, M, Tirone, G, Romario, U, Petz, W, Caracino, V, Rossetti, V, Verza, L, Vescovi, L, Marini, M, Vettoretto, N, Botteri, E, Vincenti, L, Giannandrea, G, Viora, T, Maganuco, L, Veronesi, P, Zani, B, Zanus, G, Brizzolari, M, Zanzi, F, Guariniello, A, Zappa, M, Galfrascoli, E, Zonta, S, Oragano, L, Zuliani, W, and Chiari, D
Subjects: Laparoscopic surgery, Settore MED/18 - CHIRURGIA GENERALE, medicine.medical_treatment, laparoscopy, COVID-19, Elective surgery, Emergency surgery, Survey, Oral Health, cross infection (MeSH), Surveys and Questionnaires, Epidemiology, Pandemic, Infection control, Practice Patterns, Physicians', emergency surgery, Laparoscopy, humans, medicine.diagnostic_test, General Commentary, laparoscopic surgery, infection control, Italy, physicians', Original Article, Elective Surgical Procedure, Human, heating ventilation air conditioning, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), fallow period, elective surgical procedures, pandemics, NO, aerosol generating procedures, elective surgery, survey, practice patterns, physicians', SARS-CoV-2, surveys and questionnaires, medicine, Infection Control, business.industry, General surgery, practice patterns, Surgery, business
Abstract: Background The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted the surgical community. Recommendations have been published to manage patients needing surgery during the COVID-19 pandemic. This survey, under the aegis of the Italian Society of Endoscopic Surgery, aims to analyze how Italian surgeons have changed their practice during the pandemic. Methods The authors designed an online survey that was circulated for completion to the Italian departments of general surgery registered in the Italian Ministry of Health database in December 2020. Questions were divided into three sections: hospital organization, screening policies, and safety profile of the surgical operation. The investigation periods were divided into the Italian pandemic phases I (March–May 2020), II (June–September 2020), and III (October–December 2020). Results Of 447 invited departments, 226 answered the survey. Most hospitals were treating both COVID-19-positive and -negative patients. The reduction in effective beds dedicated to surgical activity was significant, affecting 59% of the responding units. 12.4% of the respondents in phase I, 2.6% in phase II, and 7.7% in phase III reported that their surgical unit had been closed. 51.4%, 23.5%, and 47.8% of the respondents had at least one colleague reassigned to non-surgical COVID-19 activities during the three phases. There has been a reduction in elective (> 200 procedures: 2.1%, 20.6% and 9.9% in the three phases, respectively) and emergency ( Conclusion This survey offers three faithful snapshots of how the surgical community has reacted to the COVID-19 pandemic during its three phases. The significant reduction in surgical activity indicates that better health policies and more evidence-based guidelines are needed to make up for lost time and surgery not performed during the pandemic.
Published: 2021

23. A maChine and deep Learning Approach to predict pulmoNary hyperteNsIon in newbornS with congenital diaphragmatic Hernia (CLANNISH): Protocol for a retrospective study

Author: Isabella Fabietti, Valentina Condò, Benedetta Tafuri, Nicola Persico, Mariarosa Colnaghi, Stefano Ghirardello, Giuseppe Como, Donato Cascio, Genny Raffaeli, Maria Pierro, Ilaria Amodeo, Francesco Macchini, Fabio Mosca, Giacomo Cavallaro, Irene Borzani, Alice Griggio, Giorgio De Nunzio, Luana Conte, Amodeo, I., De Nunzio, G., Raffaeli, G., Borzani, I., Griggio, A., Conte, L., Macchini, F., Condo, V., Persico, N., Fabietti, I., Ghirardello, S., Pierro, M., Tafuri, B., Como, G., Cascio, D., Colnaghi, M., Mosca, F., Cavallaro, G., Amodeo I., De Nunzio G., Raffaeli G., Borzani I., Griggio A., Conte L., Macchini F., Condo V., Persico N., Fabietti I., Ghirardello S., Pierro M., Tafuri B., Como G., Cascio D., Colnaghi M., Mosca F., and Cavallaro G.
Subjects: Pediatrics, medicine.medical_treatment, retrospective study, Diagnostic Radiology, Cohort Studies, Study Protocol, Mathematical and Statistical Techniques, Pregnancy, Medicine and Health Sciences, Lung volumes, Multidisciplinary, medicine.diagnostic_test, Radiology and Imaging, Statistics, Software Engineering, Magnetic Resonance Imaging, Pulmonary Imaging, machine learning, Obstetric Procedures, Physical Sciences, Engineering and Technology, Medicine, Female, Cohort study, Computer and Information Sciences, medicine.medical_specialty, Imaging Techniques, Hypertension, Pulmonary, Science, Surgical and Invasive Medical Procedures, Research and Analysis Methods, Pulmonary hypertension, Computer Software, Diagnostic Medicine, Artificial Intelligence, Congenital Diaphragmatic Hernia, Pulmonary Ipertension, Deep Learning, protocol, medicine, Extracorporeal membrane oxygenation, Humans, Hernia, Statistical Methods, Retrospective Studies, Fetal surgery, business.industry, diaphragmatic hernia, segmentation, Infant, Newborn, Biology and Life Sciences, Neonates, Congenital diaphragmatic hernia, deep learning, Retrospective cohort study, Magnetic resonance imaging, medicine.disease, Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin), Hernias, Diaphragmatic, Congenital, business, Mathematics, Developmental Biology, Forecasting
Abstract: Introduction Outcome predictions of patients with congenital diaphragmatic hernia (CDH) still have some limitations in the prenatal estimate of postnatal pulmonary hypertension (PH). We propose applying Machine Learning (ML), and Deep Learning (DL) approaches to fetuses and newborns with CDH to develop forecasting models in prenatal epoch, based on the integrated analysis of clinical data, to provide neonatal PH as the first outcome and, possibly: favorable response to fetal endoscopic tracheal occlusion (FETO), need for Extracorporeal Membrane Oxygenation (ECMO), survival to ECMO, and death. Moreover, we plan to produce a (semi)automatic fetus lung segmentation system in Magnetic Resonance Imaging (MRI), which will be useful during project implementation but will also be an important tool itself to standardize lung volume measures for CDH fetuses. Methods and analytics Patients with isolated CDH from singleton pregnancies will be enrolled, whose prenatal checks were performed at the Fetal Surgery Unit of the Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico (Milan, Italy) from the 30th week of gestation. A retrospective data collection of clinical and radiological variables from newborns’ and mothers’ clinical records will be performed for eligible patients born between 01/01/2012 and 31/12/2020. The native sequences from fetal magnetic resonance imaging (MRI) will be collected. Data from different sources will be integrated and analyzed using ML and DL, and forecasting algorithms will be developed for each outcome. Methods of data augmentation and dimensionality reduction (feature selection and extraction) will be employed to increase sample size and avoid overfitting. A software system for automatic fetal lung volume segmentation in MRI based on the DL 3D U-NET approach will also be developed. Ethics and dissemination This retrospective study received approval from the local ethics committee (Milan Area 2, Italy). The development of predictive models in CDH outcomes will provide a key contribution in disease prediction, early targeted interventions, and personalized management, with an overall improvement in care quality, resource allocation, healthcare, and family savings. Our findings will be validated in a future prospective multicenter cohort study. Registration The study was registered at ClinicalTrials.gov with the identifier NCT04609163.
Published: 2021

24. Impact of the COVID-19 pandemic on surgery for thyroid cancer in Italy: nationwide retrospective study

Author: Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Novelli, G., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Pezzullo, L., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Boniardi, M., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Casal Ide, E., Chiappini, A., Chiofalo, M. G., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., De Manzini, N., DI Gioia, A., DI Resta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., Zucca, A., Medas, F, Ansaldo, G L, Avenia, N, Basili, G, Bononi, M, Bove, A, Carcoforo, P, Casaril, A, Cavallaro, G, Conzo, G, De Pasquale, L, Del Rio, P, Dionigi, G, Dobrinja, C, Docimo, G, Graceffa, G, Iacobone, M, Innaro, N, Lombardi, C P, Novelli, G, Palestini, N, Pedicini, F, Perigli, G, Pezzolla, A, Pezzullo, L, Scerrino, G, Spiezia, S, Testini, M, Calò, P G, Cipolla C, Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Novelli, G., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Pezzullo, L., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Boniardi, M., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Casal Ide, E., Chiappini, A., Chiofalo, M. G., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., De Manzini, N., DI Gioia, A., DI Resta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., and Zucca, A.
Subjects: 2019-20 coronavirus outbreak, medicine.medical_specialty, AcademicSubjects/MED00910, Coronavirus disease 2019 (COVID-19), medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pandemics, NO, Pandemic, Research Letter, medicine, humans, Thyroid cancer, Thyroid Neoplasm, LS7_4, Thyroid Neoplasms, Thyroidectomy, SARS-CoV-2, COVID-19, Pandemics, Italy, business.industry, thyroid neoplasms, Retrospective cohort study, medicine.disease, Comorbidity, comorbidity, retrospective studies, thyroidectomy, Settore MED/18 - Chirurgia Generale, Emergency medicine, Surgery, AcademicSubjects/MED00010, business
Abstract: N/A
Published: 2021

25. The THYCOVIT (Thyroid Surgery during COVID-19 pandemic in Italy) study: results from a nationwide, multicentric, case-controlled study

Author: Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Boniardi, M., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Chiofalo, M. G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Annamaria, D. A., Ide, E. C., Chiappini, A., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., Demanzini, N., Digioia, A., Diresta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., Zucca, A., Medas, Fabio, Ansaldo, Gian Luca, Avenia, Nicola, Basili, Giancarlo, Boniardi, Marco, Bononi, Marco, Bove, Aldo, Carcoforo, Paolo, Casaril, Andrea, Cavallaro, Giuseppe, Chiofalo, Maria Grazia, Conzo, Giovanni, De Pasquale, Loredana, Del Rio, Paolo, Dionigi, Gianlorenzo, Dobrinja, Chiara, Docimo, Giovanni, Graceffa, Giuseppa, Iacobone, Maurizio, Innaro, Nadia, Lombardi, Celestino Pio, Palestini, Nicola, Pedicini, Francesco, Perigli, Giuliano, Pezzolla, Angela, Scerrino, Gregorio, Spiezia, Stefano, Testini, Mario, Calò, Pietro Giorgio, Calogero, Cipolla, Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Boniardi, M., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Chiofalo, M. G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Annamaria, D. A., Ide, E. C., Chiappini, A., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., Demanzini, N., Digioia, A., Diresta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., and Zucca, A.
Subjects: COVID-19, Endocrine surgery, SARS-CoV-2, Thyroid carcinoma, Thyroidectomy, medicine.medical_specialty, medicine.medical_treatment, Thyroid Gland, Humans, Italy, Retrospective Studies, Pandemics, NO, Retrospective Studie, Pandemic, Epidemiology, medicine, Thyroid cancer, LS7_4, business.industry, Thyroid disease, Case-control study, Retrospective cohort study, medicine.disease, Surgery, Original Article, business, Human
Abstract: The outbreak of the COVID-19 pandemic has led to a disruption of surgical care. The aim of this multi-centric, retrospective study was to evaluate the impact of the pandemic on surgical activity for thyroid disease among the Italian Units of Endocrine Surgery. Three phases of the pandemic were identified based on the epidemiological situation and the public measures adopted from the Italian Government (1st phase: from 9th March to 3rd May 2020; 2nd phase: from 4th May to 14th June; 3rd phase: from 15th June to 31st). The patients operated upon during these phases were compared to those who underwent surgery during the same period of the previous year. Overall, 3892 patients from 28 Italian endocrine surgical units were included in the study, 1478 (38%) operated upon during COVID-19 pandemic, and 2414 (62%) during the corresponding period of 2019. The decrease in the number of operations was by 64.8%, 44.7% and 5.1% during the three phases of COVID-19 pandemic, compared to 2019, respectively. During the first and the second phases, the surgical activity was dedicated mainly to oncological patients. No differences in post-operative complications were noted between the two periods. Oncological activity for thyroid cancer was adequately maintained during the COVID-19 pandemic.
Published: 2021

26. Global attitudes in the management of acute appendicitis during COVID-19 pandemic: ACIE Appy Study

Author: Benedetto, Ielpo, Mauro, Podda, Gianluca, Pellino, Pata, Francesco, Gianpiero, Gravante, Salomone Di Saverio, Gallo, Gaetano, Rashid, Lui, Adam, Orengia, Aditya, Chowdary, Aditya, Kulkarni, Adnan, Kuvvetli, Adolfo, Navarro, Adolfo, Pisanu, Adrian, Smith, Adriana Cavero Ibiricu, Aeris Jane, D Nacion, Ahmad, Alsaleh, Ahmad, Alhazmi, Ahmad, Elmabri, Ajaz, Wani, Ahmet, Rencuzogullari, Aingeru Sarriugarte Lasarte, Ainhoa Valle Rubio, Akshay, Bavikatte, Akshay, Kumar, Al-Radjid, Jamiri, Alain Michel Alvarado Padilla, Alban, Cacurri, Alberto de San Ildefonso, Alberto, Porcu, Alberto, Sartori, Aldo, Rocca, Alejandro Paz Yáñez, Alejandro, Becaria, Alejandro, Solís-Peña, Aleksandar, Sretenović, Alex, Urbistondo, Alfonso, Bandin, Alfonso, Najar, Alessandro De Luca, Alex, Boddy, Alexandros, Charalabopoulos, Alexios, Tzivanakis, Alfonso, Amendola, Alfredo Ramirez-Gutierrez de Velasco, Ali Cihat Yildirim, Alice, Frontali, Alpha Oumar Toure, Alvaro, García-Granero, Amaia Martínez Roldan, Amaia Sanz Larrainzar, Amila Sanjiva Ratnayake, Ana María Gonzalez-Ganso, Ana, M Minaya-Bravo, Andre, Das, Andrea, Bondurri, Andrea, Costanzi, Andrea, Lucchi, Andrea, Mazzari, Andrea, Musig, Andrea, Peloso, Andrea, Piano, Andrea, Police, Andrei, Mihailescu, Andrés, Pouy, Angela, Romano, Iossa, Angelo, Anna Carmen Leonetti, Anna, Guariniello, Anna, Isaac, Anna Pia Delli Bovi, Antonella, Chessa, Antonella, Tromba, Antonio Álvarez Martínez, Antonio, Brillantino, Antonio, Caira, Antonio, Castaldi, Antonio, Ferronetti, Antonio, Giuliani, Antonio, Prestera, Antonio Ramos-De la Medina, Antonio, Tarasconi, Antonino, Tornambè, Arcangelo, Picciariello, Argyrios, Ioannidis, Ari, Leppäniemi, Arshad, Khan, Arshad, Rashid, Arteaga Luis Eduardo Pérez-Sánchez, Ashok, Mittal, Ashrarur Rahman Mitul, Asif, Mehraj, Asim, Laharwal, Asnel, Dorismé, Athanasios, Marinis, Atif, Iqbal, Augusto, Moncada, Bartolomeo, Braccio, Basim, Alkhafaji, Beatriz de Andrés Asenjo, Beatriz, Martin-Perez, Belinda Sánchez Pérez, Ben, Creavin, Benedetto, Calì, Beniamino, Pascotto, Benjamin, Stubbs, Benjamin Zavala Retes, Branislav, Jovanovic, Brian Kp Goh, Bruno, Sensi, Carlo, Biddau, Carlo, Gazia, Carlo, Vallicelli, Carlos Alberto Fagundes, Carlos Cerdán Santacruz, Carlos, Chirico, Carlos Javier Gómez, Carlos, Petrola, Carlos Sánchez Rodriguez, Carlos Yánez Benítez, Carmelisa, Dammaro, Carmelo Lo Faro, Caroline, Reinke, Casandra Dominguez Paez, Catalina, Oliva, Charudutt, Paranjape, Charlotte, Thomas, Chi Fung Chia, Chi Kwan Kong, Chiara De Lucia, Christian Ovalle Chao, Claudio, Arcudi, Claudio, Guerci, Clement, Chia, Cristiano, Parise, Cristina, Folliero, Cristopher, Varela, Dalya, M Ferguson, Daniel, Camacho, Daniel, Popowich, Daniel Souza Lima, Daniela, Rega, Daniele, Delogu, Daniele, Zigiotto, Danilo, Vinci, Dario, D'Antonio, Dario, Parini, David Alessio Merlini, David DE Zimmerman, David, Moro-Valdezate, Davide, Pertile, Deborah Maria Giusti, Deborah, S Keller, Delko, Tarik, Denis, Kalivaçi, Dennis, Mazingi, Diana Gabriela Maldonado-Pintado, Diego, Sasia, Dimitrios, Linardoutsos, Dixon, Osilli, Domenico, Murrone, Domenico, Russello, Edgar, Rodas, Edisson Alberto Acuña Roa, Edoardo, Ricciardi, Edoardo, Rosso, Edoardo, Saladino, Eduardo, Flores-Villalba, Eduardo Ruiz Ajs, Eduardo, Smith-Singares, Efstratia, Baili, Efstratios, Kouroumpas, Eirini, Bourmpouteli, Eleftheria, Douka, Elena, Martin-Perez, Eleonora, Guaitoli, Elgun, Samadov, Elisa, Francone, Elisa, Vaterlini, Emilio, Morales, Emilio, Peña, Enhao, Zhao, Eneko Del Pozo Andres, Enrico, Benzoni, Enrico, Erdas, Enrico, Pinotti, Enrique, Colás-Ruiz, Erman, Aytac, Ernesto, Laterza, Ervis, Agastra, Esteban, Foianini, Esteban, Moscoso, Estefania, Laviano, Ester, Marra, Eugenia, Cardamone, Eugenio, Licardie, Eustratia, Mpaili, Eva, Pinna, Evaristo, Varo, Fabian Martín Navarro, Fabio, Marino, Fabio, Medas, Fabio, Romano, Fatlum, Maraska, Fatmir, Saliu, Fausto, Madrid, Fausto, Rosa, Federica, Mastella, Federico, Gheza, Federico, Luvisetto, Felipe, Alconchel, Felipe Monge Vieira, Felipe, Pareja, Ferdinando, Agresta, Fernanda, Luna, Fernando, Bonilla, Fernando, Cordera, Fernando, Burdió, Fernando, Mendoza-Moreno, Fernando Muñoz Flores, Fernando Pardo Aranda, Fiona, Taylor, Flavia, L Ramos, Flavio, Fernandes, Francesca Paola Tropeano, Francesco, Balestra, Francesco, Bianco, Francesco, Ceci, Francesco, Colombo, Francesco Di Marzo, Francesco, Ferrara, Francesco, Lancellotti, Francesco, Lazzarin, Francesco, Litta, Francesco, Martini, Francesco, Pizza, Francesco, Roscio, Francesco, Virdis, Francisco Blanco Antona, Francisco Cervantes Ramírez, Francisco Miguel Fernandez, Francisco Oliver Llinares, Francisco, Quezada, Francisco, Schlottmann, Gabriel, Herrera-Almario, Gabriel, Massaferro, Gabriele, Bislenghi, Gabrielle van Ramshorst, Gaetano, Gallo, Gaetano, Luglio, Georgios, Bointas, Georgios, Kampouroglou, Georgios, Papadopoulos, Gerardo Arredondo Manrique, Giacomo, Calini, Giacomo, Nastri, Giampaolo, Formisano, Giampaolo, Galiffa, Gian Marco Palini, Gianluca, Colucci, Gianluca, Pagano, Gianluca, Vanni, Gianmaria Casoni Pattacini, Gilda De Paola, Giorgio, Lisi, Giovanna, Partida, Giovanni, Bellanova, Giovanni De Nobili, Giovanni Sammy Necchi, Giovanni, Sinibaldi, Giovanni, Tebala, Giulia, Bagaglini, Giuliano, Izzo, Giulio, Argenio, Giuseppe, Brisinda, Giuseppe, Candilio, Giuseppe Di Grezia, Giuseppe, Esposito, Giuseppe, Faillace, Giuseppe, Frazzetta, Giuseppe La Gumina, Giuseppe, Nigri, Giuseppe, Romeo, Gloria Chocarro Amatriaín, Gloria, Ortega, Gonzalo, Martin-Martin, Gregor, A Stavrou, Gunadi, Gustavo Armand Ugon, Gustavo, Machain, Gustavo, Marcucci, Gustavo, Martínez-Mier, Gustavo Miguel Machain, Gustavo, Nari, Haydée, Calvo, Hamada, Fathy, Hamilto, Hazem, Ahmed, Hazem, Faraj, Hector, Nava, Hector Ordas Macias, Herald, Nikaj, Heriberto, Solano, Huma Ahmed Khan, Humberto Sánchez Alarcón, Husam, Ebied, Iacopo, Giani, Ibabe Villalabeitia Ateca, Ignacio, Neri, Igor Alberdi San Roman, Iliya, Fidoshev, Iñaki Martinez Rodriguez, Ionut, Negoi, Irene, Ortega, Irina, Bernescu, Iris Shari Russo, Irune Vincente Rodríguez, Irving, Palomares, Isaac, Baltazar, Isabel Jaén Torrejimeno, Isabel María Cornejo Jurado, Isabella, Reccia, Ishtiyaq, Hussain, Ismael Brito Toledo, Ismael, Mora-Guzmán, Iulia, Dogaru, Ivan, Romic, Izaskun, Balciscueta, J Cleo Kenington, Jackison, Sagolsem, Jae, Y Jang, James, Olivier, Jan, Lammel-Lindemann, Jana, Dziakova, Javier Ismael Roldán Villavicencio, Javier, Salinas, Jelena, Pejanovic, Jose Gustavo Parreira, Jovanovic, Jeny Rincón Pérez, Jeryl, Asreyes, Jesus Antonio Medina Luque, Joanna, Mak, Joanne Salas Rodriguez, Johnn Henry Herrera Kok, Jon, Krook, Jose Antonio Diaz-Elizondo, Jose, Castell, José Eduardo García-Flores, José María Jover Navalón, Jose Mauro Silva Rodrigues, José, Pereira, José Tomas Castell Gómez, Juan Bellido Luque, Juan Carlos Martín Del Olmo, Juan Carlos Salamea, Juan Francisco Coronel Olivier, Juan Luis Blas Laina, Juliana Maria Ordoñez, Julieta, Gutierrez, Julio, Abba, Junaid Ahmad Sofi, Kashaf, Sherafgan, Kapil, Sahnan, Katsuhiko, Yanaga, Kevin, Beatson, Laharwal, Asim, Laura, Alvarez, Leandro, Siragusa, Lee, Farber, Lester, Ong, Liarakos, Athanasios, Lorena, García-Bruña, Luca De Martino, Luca, Ferrario, Luca, Giordano, Luca, Gordini, Luca, Pio, Luca, Ponchietti, Lucia, Moletta, Luciano, Curella, Luciano, Poggi, Lucio, Taglietti, Luigi, Bonavina, Luigi, Conti, Luigi, Goffredi, Luis Angel Garcia Ruiz, Luis, Barrionuevo, Luis Enrique Fregoso, Luis, F Cabrera, Luis, G Rodriguez, Luis, Grande, Luis Gregorio Osoria, Luis Javier Kantun Gonzalez, Luis, Sánchez-Guillén, Luis, Tallon-Aguilar, Luis, Tresierra, Luisa, Giavarini, Mahmoud, Hasabelnabi, Maja, Odovic, Mamoru, Uemura, Mansoor, Khan, Manuel, Artiles-Armas, Mara, David, Marcello Di Martino, Marcello Giuseppe Spampinato, Marcelo A, F Ribeiro, Marcelo, Viola, Marco, Angrisani, Marco, Calussi, Marco, Cannistrà, Marco, Catarci, Marco, Cereda, Marco, Conte, Marco, Giordano, Marco, Pellicciaro, Marco Vito Marino, Maria, E Vaterlini, María, F Jiménez, María Giulia Lolli, Bellini, MARIA IRENE, Maria, Lemma, Maria Michela Chiarello, Maria, Nicola, Mario, Arrigo, Mario Caneda Mejia, Mario Montes Manrique, Mario, Rodriguez-Lopez, Mario, Serradilla-Martín, Mario Zambrano Lara, Marisa, Martínez, Mark, Bagnall, Mark, Peter, Marta Cañón Lara, Marta Jimenez Gomez, Marta, Paniagua-Garcia-Señorans, Marta Perez Gonzalez, Martin, Rutegård, Martin, Salö, Marzia, Franceschilli, Massimiliano, Silveri, Massimiliano, Veroux, Massimo, Pezzulo, Matteo, Nardi, Matteo, Rottoli, Matti, Tolonen, Mauricio Pedraza Ciro, Mauricio, Zuluagua, Maurizio, Cannavò, Maurizio, Cervellera, Maurizio, Iacobone, Mauro, Montuori, Melody García Domínguez, Meltem, Bingol-Kologlu, Mian, Tahir, Michael, Lim, Michael Sj Wilson, Michael, Wilson, Michela, Campanelli, Michele, Bisaccia, Michele De Rosa, Michele, Maruccia, Michele, Paterno, Michele, Pisano, Michele, Torre, Michele, Treviño, Michele, Zuolo, Miguel, A Hernandez Bartolome, Miguel, Farina, Miguel, Pera, Miguel Prieto Calvo, Milagros, Sotelo, Min Myat Thway, Mohamed, Hassan, Mohamed Salah Eldin Hassan, Mohammad, Azfar, Mohammad, Bouhuwaish, Mohammad, Taha, Mohammad, Zaieem, Mohammed, Korkoman, Montserrat, Guraieb, Mostafa, Shalaby, Muhammad Asif Raza, Muhammad Umar Younis, Muhammed, Elhadi, Mujahid Zulfiqar Ali, Nadeem, Quazi, Nagendra, N Dudi-Venkata, Nahar, Alselaim, Natasha, Loria, Nathalie Villan Ramírez, Nay Win Than, Neil, Smart, Nelson, Trelles, Nicanor, Pinto, Niccolò, Allievi, Niccolo, Petrucciani, Nicola, Antonacci, Nicola, Cillara, Nicolae, Gica, Nicolaescu Diana Cristiana, Nicolás, Nicolás, Nicolò, Falco, Nicolò, Pecorelli, Nicolò, Tamini, Nikolaos Andreas Dallas, Nikolaos, Machairas, Noelia, Brito, Nura Ahmed Fieturi, Nuria, Ortega, Octavio, Avilamercado, Oktay, Irkorucu, Omar, Alsherif, Orestes, Valles, Orestis, Ioannidis, Oscar Hernández Palmas, Oscar Isaac Hernandez Palmas, Oscar Sanz Guadarrama, Osman, Bozbiyik, Pablo, Omelanczuk, Pablo, Ottolino, Pablo, Rodrigues, Pablo, Ruiz, Paola, Campenni, Paola, Chiarade, Paola Prieto Olivares, Paolo, Baroffio, Pascal, Wintringer, Pasquale Di Fronzo, Pasquale, Talento, Pasqualino, Favoriti, Patricia, Sendino, Patrizia, Marsanic, Patricia, Mifsut, Paúl, Andrade, Pawel, Ajawin, Valentina, Ferri, Giuseppe Massimiliano de Luca, Sara, Ingallinella, Eva, Pueyo, Francesco, Palmieri, Jesus, Silva, Ken Min Chin, Nicholas, Syn, Brian K, P Goh, Ye Xin Koh, Valeria, Tonini, Ana, Gonzales-Ganso, Vicente, Simó, Maria Victoria Diago, Pedro, Abadía-Barnó, Pedro Alfonso Najar Castañeda, Pedro Omar Sillas Arevalos, Pedro Palazón Bellver, Peng Soon Koh, Petry, Souza, Piotr, Major, Rajandeep Singh Bali, Rakesh Mohan Khattar, Renato Bessa Melo, Reza, Ebrahiminia, Ricardo, Azar, Ricardo López Murga, Riccardo, Caruso, Riccardo, Pirolo, Richard, Brady, Richard Justin Davies, Rishi, Dholakia, Rishi, Rattan, Rishi, Singhal, Robert, Lim, Roberta, Angelico, Roberta Maria Isernia, Roberta, Tutino, Roberto, Faccincani, Roberto, Peltrini, Rocío, Carrera-Ceron, Rodrigo, Tejos, Rohit, Kashyap, Roosevelt, Fajardo, Rosa, Lozito, Royer Madariaga Pareja, Sabrina, Garbarino, Salvador, Morales-Conde, Sami, Benli, Sami, Mansour, Samir, Flores, Samuel Limon Suarez, Santiago Lopez Ben, Sara, Fuentes, Sara, Napetti, Sara Ortiz de Guzmán, Selmy, Awad, Sergio, A Weckmann Luján, Sergio, Gentilli, Sergio, Grimaldi, Sergio Olivares Pizarro, Serkan, Tayar, Shakeeb, Nabi, Shannon, M Chan, Sheikh, Junaid, Sidney, Rojas, Silvana, Monetti, Silvia, García, Silvia, Salvans, Silvia, Tenconi, Simon, Shaw, Simone, Santoni, Sofia Andrea Parra, Sofía, Cárdenas, Sonia, Pérez-Bertólez, Sonja, Chiappetta, Sophie, Dessureault, Spiros, Delis, Stefano Amore Bonapasta, Stefano, Rausei, Stefano, Scaringi, Sundeep, Keswani, Syed Muhammad Ali, Süleyman, Cetinkunar, Tak Lit Derek Fung, Tariq, Rawashdeh, Tatiana Nicolás López, Tercio De Campos, Teresa Calderon Duque, Teresa, Perra, Theodore, Liakakos, Theodoros, Daskalakis, Theodoros, Liakakos, Thomas, Barnes, Tijmen, Koëter, Tiku, Zalla, Tomás, E González, Tomás, Elosua, Tommaso, Campagnaro, Tommy, Brown, Topi, Luoto, Touré Alpha Oumar, Ugo, Giustizieri, Ugo, Grossi, Umberto, Bracale, Uriel, Rivas, Valentina, Sosa, Valentina, Testa, Valeria, Andriola, Valerio, Balassone, Valerio, Celentano, Valerio, Progno, Varun, Raju, Vanessa, Carroni, Venera, Cavallaro, Venkateswara Rao Katta, Veronica De Simone, Vicent Primo Romaguera, Victor Hugo García Orozco, Victor, Luraschi, Victor, Rachkov, Victor, Turrado-L, Victor, Visag-Castillo, Victoria, Dowling, Victoria, Graham, Vincenzo, Papagni, Vincenzo, Vigorita, Vinicius Cordeiro Fonseca, Virginia Jimenez Carneros, Vittoria, Bellato, Walyson, Gonçalves, William, F Powers, William, Grigg, Wolf, O Bechstein, Yu Bing Lim, Yuksel, Altinel, Zoran, Golubović, Zutoia, Balciscueta, Ielpo B., Podda M., Pellino G., Pata F., Caruso R., Gravante G., Di Saverio S., Gallo G., Lui R., Orengia A., Chowdary A., Kulkarni A., Kuvvetli A., Navarro A., Pisanu A., Smith A., Ibiricu A.C., Nacion A.J.D., Alsaleh A., Alhazmi A., Elmabri A., Wani A., Rencuzogullari A., Lasarte A.S., Rubio A.V., Bavikatte A., Kumar A., Jamiri A.-R., Padilla A.M.A., Cacurri A., de San Ildefonso A., Porcu A., Sartori A., Rocca A., Yanez A.P., Becaria A., Solis-Pena A., Sretenovic A., Urbistondo A., Bandin A., Najar A., De Luca A., Boddy A., Charalabopoulos A., Tzivanakis A., Amendola A., de Velasco A.R.-G., Yildirim A.C., Frontali A., Toure A.O., Garcia-Granero A., Roldan A.M., Larrainzar A.S., Ratnayake A.S., Gonzalez-Ganso A.M., Minaya-Bravo A.M., Das A., Bondurri A., Costanzi A., Lucchi A., Mazzari A., Musig A., Peloso A., Piano A., Police A., Mihailescu A., Pouy A., Romano A., Iossa A., Leonetti A.C., Guariniello A., Isaac A., Bovi A.P.D., Chessa A., Tromba A., Martinez A.A., Brillantino A., Caira A., Castaldi A., Ferronetti A., Giuliani A., Prestera A., la Medina A.R.-D., Tarasconi A., Tornambe A., Picciariello A., Ioannidis A., Leppaniemi A., Khan A., Rashid A., Perez-Sanchez A.L.E., Mittal A., Mitul A.R., Mehraj A., Laharwal A., Dorisme A., Marinis A., Iqbal A., Moncada A., Braccio B., Alkhafaji B., de Andres Asenjo B., Martin-Perez B., Perez B.S., Creavin B., Cali B., Pascotto B., Stubbs B., Retes B.Z., Jovanovic B., Goh B.K.P., Sensi B., Biddau C., Gazia C., Vallicelli C., Fagundes C.A., Santacruz C.C., Chirico C., Diaz C.J.G., Petrola C., Rodriguez C.S., Benitez C.Y., Dammaro C., Faro C.L., Reinke C., Paez C.D., Oliva C., Paranjape C., Thomas C., Chia C.F., Kong C.K., De Lucia C., Chao C.O., Arcudi C., Guerci C., Chia C., Parise C., Folliero C., Varela C., Ferguson D.M., Camacho D., Popowich D., Lima D.S., Rega D., Delogu D., Zigiotto D., Vinci D., D'Antonio D., Parini D., Merlini D.A., Zimmerman D.D.E., Moro-Valdezate D., Pertile D., Giusti D.M., Keller D.S., Tarik D., Kalivaci D., Mazingi D., Maldonado-Pintado D.G., Sasia D., Linardoutsos D., Osilli D., Murrone D., Russello D., Rodas E., Roa E.A.A., Ricciardi E., Rosso E., Saladino E., Flores-Villalba E., Ajs E.R., Smith-Singares E., Baili E., Kouroumpas E., Bourmpouteli E., Douka E., Martin-Perez E., Guaitoli E., Samadov E., Francone E., Vaterlini E., Morales E., Pena E., Zhao E., Andres E.D.P., Benzoni E., Erdas E., Pinotti E., Colas-Ruiz E., Aytac E., Laterza E., Agastra E., Foianini E., Moscoso E., Laviano E., Marra E., Cardamone E., Licardie E., Mpaili E., Pinna E., Varo E., Navarro F.M., Marino F., Medas F., Romano F., Maraska F., Saliu F., Madrid F., Rosa F., Mastella F., Gheza F., Luvisetto F., Alconchel F., Vieira F.M., Pareja F., Agresta F., Luna F., Bonilla F., Cordera F., Burdio F., Mendoza-Moreno F., Flores F.M., Aranda F.P., Taylor F., Ramos F.L., Fernandes F., Tropeano F.P., Balestra F., Bianco F., Ceci F., Colombo F., Di Marzo F., Ferrara F., Lancellotti F., Lazzarin F., Litta F., Martini F., Pizza F., Roscio F., Virdis F., Antona F.B., Ramirez F.C., Fernandez F.M., Llinares F.O., Quezada F., Schlottmann F., Herrera-Almario G., Massaferro G., Bislenghi G., van Ramshorst G., Luglio G., Bointas G., Kampouroglou G., Papadopoulos G., Manrique G.A., Calini G., Nastri G., Formisano G., Galiffa G., Palini G.M., Colucci G., Pagano G., Vanni G., Pattacini G.C., De Paola G., Lisi G., Partida G., Bellanova G., De Nobili G., Necchi G.S., Sinibaldi G., Tebala G., Bagaglini G., Izzo G., Argenio G., Brisinda G., Candilio G., Di Grezia G., Esposito G., Faillace G., Frazzetta G., La Gumina G., Nigri G., Romeo G., Amatriain G.C., Ortega G., Martin-Martin G., Stavrou G.A., Gunadi, Ugon G.A., Machain G., Marcucci G., Martinez-Mier G., Machain G.M., Nari G., Calvo H., Fathy H., Hamilto, Ahmed H., Faraj H., Nava H., Macias H.O., Nikaj H., Solano H., Khan H.A., Alarcon H.S., Ebied H., Giani I., Ateca I.V., Neri I., Roman I.A.S., Fidoshev I., Rodriguez I.M., Negoi I., Ortega I., Bernescu I., Russo I.S., Rodriguez I.V., Palomares I., Baltazar I., Torrejimeno I.J., Jurado I.M.C., Reccia I., Hussain I., Toledo I.B., Mora-Guzman I., Dogaru I., Romic I., Balciscueta I., Kenington J.C., Sagolsem J., Jang J.Y., Olivier J., Lammel-Lindemann J., Dziakova J., Villavicencio J.I.R., Salinas J., Parreira J.P.J.G., Jovanovic, Perez J.R., Reyes J.A.S., Luque J.A.M., Mak J., Rodriguez J.S., Kok J.H.H., Krook J., Diaz-Elizondo J.A., Castell J., Garcia-Flores J.E., Navalon J.M.J., Rodrigues J.M.S., Pereira J., Gomez J.T.C., Luque J.B., del Olmo J.C.M., Salamea J.C., Olivier J.F.C., Laina J.L.B., Ordonez J.M., Gutierrez J., Abba J., Sofi J.A., Sherafgan K., Sahnan K., Yanaga K., Beatson K., Asim L., Alvarez L., Siragusa L., Farber L., Ong L., Athanasios L., Garcia-Bruna L., De Martino L., Ferrario L., Giordano L., Gordini L., Pio L., Ponchietti L., Moletta L., Curella L., Poggi L., Taglietti L., Bonavina L., Conti L., Goffredi L., Ruiz L.A.G., Barrionuevo L., Fregoso L.E., Cabrera L.F., Rodriguez L.G., Grande L., Osoria L.G., Gonzalez L.J.K., Sanchez-Guillen L., Tallon-Aguilar L., Tresierra L., Giavarini L., Hasabelnabi M., Odovic M., Uemura M., Khan M., Artiles-Armas M., David M., Di Martino M., Spampinato M.G., Ribeiro M.A.F., Viola M., Angrisani M., Calussi M., Cannistra M., Catarci M., Cereda M., Conte M., Giordano M., Pellicciaro M., Marino M.V., Vaterlini M.E., Jimenez M.F., Lolli M.G., Bellini M.I., Lemma M., Chiarello M.M., Nicola M., Arrigo M., Mejia M.C., Manrique M.M., Rodriguez-Lopez M., Serradilla-Martin M., Lara M.Z., Martinez M., Bagnall M., Peter M., Lara M.C., Gomez M.J., Paniagua-Garcia-Senorans M., Gonzalez M.P., Rutegard M., Salo M., Franceschilli M., Silveri M., Veroux M., Pezzulo M., Nardi M., Rottoli M., Tolonen M., Ciro M.P., Zuluagua M., Cannavo M., Cervellera M., Iacobone M., Montuori M., Dominguez M.G., Bingol-Kologlu M., Tahir M., Lim M., Wilson M.S., Wilson M., Campanelli M., Bisaccia M., De Rosa M., Maruccia M., Paterno M., Pisano M., Torre M., Trevino M., Zuolo M., Hernandez Bartolome M.A., Farina M., Pera M., Calvo M.P., Sotelo M., Thway M.M., Hassan M., Hassan M.S.E., Azfar M., Bouhuwaish M., Taha M., Zaieem M., Korkoman M., Guraieb M., Shalaby M., Raza M.A., Younis M.U., Elhadi M., Ali M.Z., Quazi N., Dudi-Venkata N.N., Alselaim N., Loria N., Ramirez N.V., Than N.W., Smart N., Trelles N., Pinto N., Allievi N., Petrucciani N., Antonacci N., Cillara N., Gica N., Cristiana N.D., Krystek N., Falco N., Pecorelli N., Tamini N., Dallas N.A., Machairas N., Brito N., Fieturi N.A., Ortega N., Mercado O.A., Irkorucu O., Alsherif O., Valles O., Ioannidis O., Palmas O.H., Palmas O.I.H., Guadarrama O.S., Bozbiyik O., Omelanczuk P., Ottolino P., Rodrigues P., Ruiz P., Campenni P., Chiarade P., Olivares P.P., Baroffio P., Panaccio P., Wintringer P., Di Fronzo P., Talento P., Favoriti P., Sendino P., Marsanic P., Mifsut P., Andrade P., Ajawin P., Abadia-Barno P., Castaneda P.A.N., Arevalos P.O.S., Bellver P.P., Koh P.S., Souza P., Major P., Bali R.S., Khattar R.M., Melo R.B., Ebrahiminia R., Azar R., Murga R.L., Pirolo R., Brady R., Davies R.J., Dholakia R., Rattan R., Singhal R., Lim R., Angelico R., Isernia R.M., Tutino R., Faccincani R., Peltrini R., Carrera-Ceron R., Tejos R., Kashyap R., Fajardo R., Lozito R., Pareja R.M., Garbarino S., Morales-Conde S., Benli S., Mansour S., Flores S., Suarez S.L., Ben S.L., Fuentes S., Napetti S., de Guzman S.O., Awad S., Weckmann Lujan S.A., Gentilli S., Grimaldi S., Pizarro S.O., Tayar S., Nabi S., Chan S.M., Junaid S., Rojas S., Monetti S., Garcia S., Salvans S., Tenconi S., Shaw S., Santoni S., Parra S.A., Cardenas S., Perez-Bertolez S., Chiappetta S., Dessureault S., Delis S., Bonapasta S.A., Rausei S., Scaringi S., Keswani S., Ali S.M., Cetinkunar S., Fung T.L.D., Rawashdeh T., Lopez T.N., De Campos T., Duque T.C., Perra T., Liakakos T., Daskalakis T., Barnes T., Koeter T., Zalla T., Gonzalez T.E., Elosua T., Campagnaro T., Brown T., Luoto T., Oumar T.A., Giustizieri U., Grossi U., Bracale U., Rivas U., Sosa V., Testa V., Andriola V., Tonini V., Balassone V., Celentano V., Progno V., Raju V., Carroni V., Cavallaro V., Katta V.R., De Simone V., Romaguera V.P., Orozco V.H.G., Luraschi V., Rachkov V., Turrado-L V., Visag-Castillo V., Dowling V., Graham V., Papagni V., Vigorita V., Fonseca V.C., Carneros V.J., Bellato V., Goncalves W., Powers W.F., Grigg W., Bechstein W.O., Lim Y.B., Altinel Y., Golubovic Z., Balciscueta Z., Ielpo, B., Podda, M., Pellino, G., Pata, F., Caruso, R., Gravante, G., Di Saverio, S., Gallo, G., Lui, R., Orengia, A., Chowdary, A., Kulkarni, A., Kuvvetli, A., Navarro, A., Pisanu, A., Smith, A., Ibiricu, A. C., Nacion, A. J. D., Alsaleh, A., Alhazmi, A., Elmabri, A., Wani, A., Rencuzogullari, A., Lasarte, A. S., Rubio, A. V., Bavikatte, A., Kumar, A., Jamiri, A. -R., Padilla, A. M. A., Cacurri, A., de San Ildefonso, A., Porcu, A., Sartori, A., Rocca, A., Yanez, A. P., Becaria, A., Solis-Pena, A., Sretenovic, A., Urbistondo, A., Bandin, A., Najar, A., De Luca, A., Boddy, A., Charalabopoulos, A., Tzivanakis, A., Amendola, A., de Velasco, A. R. -G., Yildirim, A. C., Frontali, A., Toure, A. O., Garcia-Granero, A., Roldan, A. M., Larrainzar, A. S., Ratnayake, A. S., Gonzalez-Ganso, A. M., Minaya-Bravo, A. M., Das, A., Bondurri, A., Costanzi, A., Lucchi, A., Mazzari, A., Musig, A., Peloso, A., Piano, A., Police, A., Mihailescu, A., Pouy, A., Romano, A., Iossa, A., Leonetti, A. C., Guariniello, A., Isaac, A., Bovi, A. P. D., Chessa, A., Tromba, A., Martinez, A. A., Brillantino, A., Caira, A., Castaldi, A., Ferronetti, A., Giuliani, A., Prestera, A., la Medina, A. R. -D., Tarasconi, A., Tornambe, A., Picciariello, A., Ioannidis, A., Leppaniemi, A., Khan, A., Rashid, A., Perez-Sanchez, A. L. E., Mittal, A., Mitul, A. R., Mehraj, A., Laharwal, A., Dorisme, A., Marinis, A., Iqbal, A., Moncada, A., Braccio, B., Alkhafaji, B., de Andres Asenjo, B., Martin-Perez, B., Perez, B. S., Creavin, B., Cali, B., Pascotto, B., Stubbs, B., Retes, B. Z., Jovanovic, B., Goh, B. K. P., Sensi, B., Biddau, C., Gazia, C., Vallicelli, C., Fagundes, C. A., Santacruz, C. C., Chirico, C., Diaz, C. J. G., Petrola, C., Rodriguez, C. S., Benitez, C. Y., Dammaro, C., Faro, C. L., Reinke, C., Paez, C. D., Oliva, C., Paranjape, C., Thomas, C., Chia, C. F., Kong, C. K., De Lucia, C., Chao, C. O., Arcudi, C., Guerci, C., Chia, C., Parise, C., Folliero, C., Varela, C., Ferguson, D. M., Camacho, D., Popowich, D., Lima, D. S., Rega, D., Delogu, D., Zigiotto, D., Vinci, D., D'Antonio, D., Parini, D., Merlini, D. A., Zimmerman, D. D. E., Moro-Valdezate, D., Pertile, D., Giusti, D. M., Keller, D. S., Tarik, D., Kalivaci, D., Mazingi, D., Maldonado-Pintado, D. G., Sasia, D., Linardoutsos, D., Osilli, D., Murrone, D., Russello, D., Rodas, E., Roa, E. A. A., Ricciardi, E., Rosso, E., Saladino, E., Flores-Villalba, E., Ajs, E. R., Smith-Singares, E., Baili, E., Kouroumpas, E., Bourmpouteli, E., Douka, E., Martin-Perez, E., Guaitoli, E., Samadov, E., Francone, E., Vaterlini, E., Morales, E., Pena, E., Zhao, E., Andres, E. D. P., Benzoni, E., Erdas, E., Pinotti, E., Colas-Ruiz, E., Aytac, E., Laterza, E., Agastra, E., Foianini, E., Moscoso, E., Laviano, E., Marra, E., Cardamone, E., Licardie, E., Mpaili, E., Pinna, E., Varo, E., Navarro, F. M., Marino, F., Medas, F., Romano, F., Maraska, F., Saliu, F., Madrid, F., Rosa, F., Mastella, F., Gheza, F., Luvisetto, F., Alconchel, F., Vieira, F. M., Pareja, F., Agresta, F., Luna, F., Bonilla, F., Cordera, F., Burdio, F., Mendoza-Moreno, F., Flores, F. M., Aranda, F. P., Taylor, F., Ramos, F. L., Fernandes, F., Tropeano, F. P., Balestra, F., Bianco, F., Ceci, F., Colombo, F., Di Marzo, F., Ferrara, F., Lancellotti, F., Lazzarin, F., Litta, F., Martini, F., Pizza, F., Roscio, F., Virdis, F., Antona, F. B., Ramirez, F. C., Fernandez, F. M., Llinares, F. O., Quezada, F., Schlottmann, F., Herrera-Almario, G., Massaferro, G., Bislenghi, G., van Ramshorst, G., Luglio, G., Bointas, G., Kampouroglou, G., Papadopoulos, G., Manrique, G. A., Calini, G., Nastri, G., Formisano, G., Galiffa, G., Palini, G. M., Colucci, G., Pagano, G., Vanni, G., Pattacini, G. C., De Paola, G., Lisi, G., Partida, G., Bellanova, G., De Nobili, G., Necchi, G. S., Sinibaldi, G., Tebala, G., Bagaglini, G., Izzo, G., Argenio, G., Brisinda, G., Candilio, G., Di Grezia, G., Esposito, G., Faillace, G., Frazzetta, G., La Gumina, G., Nigri, G., Romeo, G., Amatriain, G. C., Ortega, G., Martin-Martin, G., Stavrou, G. A., Ugon, G. A., Machain, G., Marcucci, G., Martinez-Mier, G., Machain, G. M., Nari, G., Calvo, H., Fathy, H., Ahmed, H., Faraj, H., Nava, H., Macias, H. O., Nikaj, H., Solano, H., Khan, H. A., Alarcon, H. S., Ebied, H., Giani, I., Ateca, I. V., Neri, I., Roman, I. A. S., Fidoshev, I., Rodriguez, I. M., Negoi, I., Ortega, I., Bernescu, I., Russo, I. S., Rodriguez, I. V., Palomares, I., Baltazar, I., Torrejimeno, I. J., Jurado, I. M. C., Reccia, I., Hussain, I., Toledo, I. B., Mora-Guzman, I., Dogaru, I., Romic, I., Balciscueta, I., Kenington, J. C., Sagolsem, J., Jang, J. Y., Olivier, J., Lammel-Lindemann, J., Dziakova, J., Villavicencio, J. I. R., Salinas, J., Parreira, J. P. J. G., Perez, J. R., Reyes, J. A. S., Luque, J. A. M., Mak, J., Rodriguez, J. S., Kok, J. H. H., Krook, J., Diaz-Elizondo, J. A., Castell, J., Garcia-Flores, J. E., Navalon, J. M. J., Rodrigues, J. M. S., Pereira, J., Gomez, J. T. C., Luque, J. B., del Olmo, J. C. M., Salamea, J. C., Olivier, J. F. C., Laina, J. L. B., Ordonez, J. M., Gutierrez, J., Abba, J., Sofi, J. A., Sherafgan, K., Sahnan, K., Yanaga, K., Beatson, K., Asim, L., Alvarez, L., Siragusa, L., Farber, L., Ong, L., Athanasios, L., Garcia-Bruna, L., De Martino, L., Ferrario, L., Giordano, L., Gordini, L., Pio, L., Ponchietti, L., Moletta, L., Curella, L., Poggi, L., Taglietti, L., Bonavina, L., Conti, L., Goffredi, L., Ruiz, L. A. G., Barrionuevo, L., Fregoso, L. E., Cabrera, L. F., Rodriguez, L. G., Grande, L., Osoria, L. G., Gonzalez, L. J. K., Sanchez-Guillen, L., Tallon-Aguilar, L., Tresierra, L., Giavarini, L., Hasabelnabi, M., Odovic, M., Uemura, M., Khan, M., Artiles-Armas, M., David, M., Di Martino, M., Spampinato, M. G., Ribeiro, M. A. F., Viola, M., Angrisani, M., Calussi, M., Cannistra, M., Catarci, M., Cereda, M., Conte, M., Giordano, M., Pellicciaro, M., Marino, M. V., Vaterlini, M. E., Jimenez, M. F., Lolli, M. G., Bellini, M. I., Lemma, M., Chiarello, M. M., Nicola, M., Arrigo, M., Mejia, M. C., Manrique, M. M., Rodriguez-Lopez, M., Serradilla-Martin, M., Lara, M. Z., Martinez, M., Bagnall, M., Peter, M., Lara, M. C., Gomez, M. J., Paniagua-Garcia-Senorans, M., Gonzalez, M. P., Rutegard, M., Salo, M., Franceschilli, M., Silveri, M., Veroux, M., Pezzulo, M., Nardi, M., Rottoli, M., Tolonen, M., Ciro, M. P., Zuluagua, M., Cannavo, M., Cervellera, M., Iacobone, M., Montuori, M., Dominguez, M. G., Bingol-Kologlu, M., Tahir, M., Lim, M., Wilson, M. S., Wilson, M., Campanelli, M., Bisaccia, M., De Rosa, M., Maruccia, M., Paterno, M., Pisano, M., Torre, M., Trevino, M., Zuolo, M., Hernandez Bartolome, M. A., Farina, M., Pera, M., Calvo, M. P., Sotelo, M., Thway, M. M., Hassan, M., Hassan, M. S. E., Azfar, M., Bouhuwaish, M., Taha, M., Zaieem, M., Korkoman, M., Guraieb, M., Shalaby, M., Raza, M. A., Younis, M. U., Elhadi, M., Ali, M. Z., Quazi, N., Dudi-Venkata, N. N., Alselaim, N., Loria, N., Ramirez, N. V., Than, N. W., Smart, N., Trelles, N., Pinto, N., Allievi, N., Petrucciani, N., Antonacci, N., Cillara, N., Gica, N., Cristiana, N. D., Krystek, N., Falco, N., Pecorelli, N., Tamini, N., Dallas, N. A., Machairas, N., Brito, N., Fieturi, N. A., Ortega, N., Mercado, O. A., Irkorucu, O., Alsherif, O., Valles, O., Ioannidis, O., Palmas, O. H., Palmas, O. I. H., Guadarrama, O. S., Bozbiyik, O., Omelanczuk, P., Ottolino, P., Rodrigues, P., Ruiz, P., Campenni, P., Chiarade, P., Olivares, P. P., Baroffio, P., Panaccio, P., Wintringer, P., Di Fronzo, P., Talento, P., Favoriti, P., Sendino, P., Marsanic, P., Mifsut, P., Andrade, P., Ajawin, P., Abadia-Barno, P., Castaneda, P. A. N., Arevalos, P. O. S., Bellver, P. P., Koh, P. S., Souza, P., Major, P., Bali, R. S., Khattar, R. M., Melo, R. B., Ebrahiminia, R., Azar, R., Murga, R. L., Pirolo, R., Brady, R., Davies, R. J., Dholakia, R., Rattan, R., Singhal, R., Lim, R., Angelico, R., Isernia, R. M., Tutino, R., Faccincani, R., Peltrini, R., Carrera-Ceron, R., Tejos, R., Kashyap, R., Fajardo, R., Lozito, R., Pareja, R. M., Garbarino, S., Morales-Conde, S., Benli, S., Mansour, S., Flores, S., Suarez, S. L., Ben, S. L., Fuentes, S., Napetti, S., de Guzman, S. O., Awad, S., Weckmann Lujan, S. A., Gentilli, S., Grimaldi, S., Pizarro, S. O., Tayar, S., Nabi, S., Chan, S. M., Junaid, S., Rojas, S., Monetti, S., Garcia, S., Salvans, S., Tenconi, S., Shaw, S., Santoni, S., Parra, S. A., Cardenas, S., Perez-Bertolez, S., Chiappetta, S., Dessureault, S., Delis, S., Bonapasta, S. A., Rausei, S., Scaringi, S., Keswani, S., Ali, S. M., Cetinkunar, S., Fung, T. L. D., Rawashdeh, T., Lopez, T. N., De Campos, T., Duque, T. C., Perra, T., Liakakos, T., Daskalakis, T., Barnes, T., Koeter, T., Zalla, T., Gonzalez, T. E., Elosua, T., Campagnaro, T., Brown, T., Luoto, T., Oumar, T. A., Giustizieri, U., Grossi, U., Bracale, U., Rivas, U., Sosa, V., Testa, V., Andriola, V., Tonini, V., Balassone, V., Celentano, V., Progno, V., Raju, V., Carroni, V., Cavallaro, V., Katta, V. R., De Simone, V., Romaguera, V. P., Orozco, V. H. G., Luraschi, V., Rachkov, V., Turrado-L, V., Visag-Castillo, V., Dowling, V., Graham, V., Papagni, V., Vigorita, V., Fonseca, V. C., Carneros, V. J., Bellato, V., Goncalves, W., Powers, W. F., Grigg, W., Bechstein, W. O., Lim, Y. B., Altinel, Y., Golubovic, Z., Balciscueta, Z., Ielpo, B, Podda, M, Pellino, G, Pata, F, Caruso, R, Gravante, G, Di Saverio, S, and Luglio, G
Subjects: medicine.medical_specialty, Anti-Bacterial Agents, Appendectomy, Appendicitis, COVID-19 Testing, Hospital Administration, Humans, Pandemics, Personal Protective Equipment, Practice Patterns, Physicians', Surveys and Questionnaires, Attitude of Health Personnel, COVID-19, Surgeons, Coronavirus disease 2019 (COVID-19), Settore MED/18 - CHIRURGIA GENERALE, COVID-19 pandemic. Acute appendicitis, MEDLINE, Practice Patterns, 030230 surgery, Health administration, 03 medical and health sciences, 0302 clinical medicine, Anti-Bacterial Agent, Pandemic, medicine, Surveys and Questionnaire, Appendiciti, General, Laparoscopy, Personal protective equipment, Physicians', medicine.diagnostic_test, business.industry, General surgery, Original Articles, medicine.disease, Anti-bacterial agents, appendectomy, appendicitis, COVID-19 testing, hospital administration, humans, pandemics, personal protective equipment, practice patterns physicians', surveys and questionnaires, attitude of health personnel, surgeons, appendicitis - COVI-19 - ACIE study - management, Acute appendicitis, Original Article, Surgery, Covid-19, business, Human
Abstract: Background Surgical strategies are being adapted to face the COVID‐19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a snapshot of worldwide approaches to appendicitis. Methods The Association of Italian Surgeons in Europe designed an online survey to assess the current attitude of surgeons globally regarding the management of patients with acute appendicitis during the pandemic. Questions were divided into baseline information, hospital organization and screening, personal protective equipment, management and surgical approach, and patient presentation before versus during the pandemic. Results Of 744 answers, 709 (from 66 countries) were complete and were included in the analysis. Most hospitals were treating both patients with and those without COVID. There was variation in screening indications and modality used, with chest X‐ray plus molecular testing (PCR) being the commonest (19·8 per cent). Conservative management of complicated and uncomplicated appendicitis was used by 6·6 and 2·4 per cent respectively before, but 23·7 and 5·3 per cent, during the pandemic (both P, The COVID‐19 pandemic required reorganization of surgical services, affecting patients with common surgical diseases including acute appendicitis. No evidence is available on the topic. This study found global variation in screening policies, use of personal protective equipment and intraoperative directives. There has been increased adoption of non‐operative management and open appendicectomy. Hands off
Published: 2021

27. Impact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic

Author: Bellato, V., Konishi, T., Pellino, G., An, Y., Piciocchi, A., Khanna, K., Campanelli, M., Efetov, S., Sica, G. S., Kefleyesus, A., Hoofwijk, A. G. M., Eldaly, A. S., Gonzalez, A., Jawad, A., Jooma, A., Hafez, A. M., Rubio, A. V., Landaluce-Olavarria, A., Wu, A., Nagatsu, A., Inoue, A., Kanamoto, A., Ouchi, A., El-Hussuna, A., Vazquez-Melero, A., Wolthuis, A. M., Peral, A. M., Lozano, A. C., Efremov, A., Ryasantsev, A. V., Giorgio, A. D., Parente, A., Tamburrini, A., Alo, A., Forero-Torres, A., Vahrmeijer, A. L., Varabei, A., Hinojosa, S., Balkan, A. Z. A., Frontali, A., Oleg, A., Soler-Silva, A., Makni, A., Andre, A., Cabrera, A. M. G., Fernandez, A. M. G., Minaya-Bravo, A. M., Rodriguez-Sanchez, A., Musina, A. -M., Pangeni, A., Zolotko, A., Tonoyan, A., Balla, A., Belli, A., Cavallaro, A., Chierici, A., Divizia, A., Bucci, A. F., Salido, A. J., Morini, A., Muratore, A., Vignali, A., Chitul, A., Sebastian, D. A., Pcolkins, A., Shchegolev, A., Hollenbeck, A., Wisneski, A., Iossa, A., D'Amore, A., Hunter, A., Hesketh, A. J., Brocca, A. L., Spinelli, A., Caires, A., D'Alessandro, A., Correo, A. F. S. L., Macri, A., Navarro-Sanchez, A., Pronk, A., Akunc, A., Mehri, A., Pelta, A., Papadopoulos, A., Kechagias, A., Rashid, A., Ramazanov, A., Chandio, A., Kohyama, A., Nishimura, A., Ohkawa, A., Dulskas, A., Jamal, A., Mariani, A., Unal, A. G., Karagoz, A., Ozkan, B. B., Salih, B., Gulcu, B., Pessia, B., Martin-Perez, B., Ielpo, B., Tulelli, B., Yang, B., Mhamed, B., Murphy, B., Pirozzi, B. M., Sensi, B., Langenhoff, B., Belevi, B., Guney, B., Ng, C., Rueda, C., Roxburgh, C. S., Feo, C. V., Ferrari, C., Gazia, C., Pratesi, C., Ratto, C., Santacruz, C. C., Arroyave, C. R. M., Macias, C., Fernandez, C. G., Fernandez, C. C., Curtis-Martinez, C., Fortmann, C., Kim, C., Galeano, C. U., Barroso, C., Baldi, C., Foppa, C., Formisano, C., Li, C., Ding, C., Wang, C., Iacusso, C., Yang, C., Pizzera, C., Skias, C., Chouliras, C., Liakos, C., Matsuda, C., C. -Y., Wu, Ozaslan, C., Tanda, C., Tommaso, C. M., Dagorno, C., Ramos, C. P. A., Arcudi, C., Coco, C., Morales, C. M., Ali, M. Z., De Azevedo, C. T. M., Lozano, C. C., Sala, C., Leo, C. A., Scarpa, C. R., Ferro, C. V., Fernandez, C. M., Morales-Garcia, D., Nakano, D., Cristian, D., Hechtl, D., Canovas, D. T., Calabrese, D., Rega, D., Ferraro, D., Morezzi, D., Sommacale, D., Brogden, D., Miskovic, D., Merlini, D., Pertile, D., Coniglio, D., Zhu, D., Wu, D., Coletta, D., Rubio, D. R., Sasia, D., Fillipov, D., Russiello, D., Dardanov, D., Consten, E. C. J., Smolskas, E., Muttillo, E. M., Jones, E., Sunami, E., Etienne, E. -H., Chalkiadaki, E., Giacomelli, E., Karbovnichaya, E., Ruiz-Ucar, E., Guaitoli, E., Samadov, E., Jovine, E., Treppiedi, E., Vaterlini, E. M., Zambaiti, E., Moggia, E., Coetzee, E., Chisari, E., D'Errico, E., Ciofic, E., Pena, E., Kurt, E., Balik, E., Gunay, E., Sivrikoz, E., Andolfi, E., Araimo, E., Lucci, E., Opocher, E., Pinotti, E., Rubino, E., Reyhan, E., Mazzotta, E., Navarro, E. B., El-Helou, E., Licardie-Bolanos, E., Porto, E. I., Contreras, E., Boerma, E. -J., Cianchi, F., Marino, F., Uggeri, F., Han, F., Calculli, F., Falaschi, F., Ghignone, F., Perrone, F., Borghi, F., Garcia, F., Agresta, F., Cananzi, F. C. M., Mendoza-Moreno, F., Cengiz, F., Almeida, F. M., Baracchi, F., Carannante, F., Torre, F. L., Fernandes, F., Friedmacher, F., Grama, F., Carissimi, F., Pecchini, F., Bianco, F., Colombo, F., Ferrara, F., Litta, F., Carrano, F. M., Martignoni, F., Tasselli, F. M., Milone, F., Pata, F., Sammartino, F., Zambianchi, F., Barragan, F., Herrero, F., Schlottmann, F., Den Boer, F. C., Pfeffer, F., Fujita, F., Navarra, G., Herrera-Almario, G., Pozzo, G., Capolupo, G. T., Van Ramshorst, G. 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A., Baini, M., De Cillia, M., De Rosa, M., Manigrasso, M., Zuolo, M., Cunha, M. F., Misca, M., Slavchev, M., Danilov, M., Shigaev, M., Martens, M., Kobayashi, M., Ren, M., Ishizuka, M., Hassan, M. M., Siblini, M., Sahloul, M., Keramati, M. R., Karunakaran, M., Markel, M., Majeed, M., Younis, M. U., Akin, M. I., Laraibe, M., Derebey, M., Kendirci, M., Fukunaga, M., Matsubara, N., Ordaz, N. E. C., Samalavicius, N. E., Keeratibharat, N., De Angelis, N., Gica, N., Mariani, N. M., Ramino, N., Falco, N., Smart, N., De Korte, N., Kok, N. F. M., Jamieson, N. B., Aberyasev, N., Bruklich, N., Ichikawa, N., Miyoshi, N., De Palma, N., Figueiredo, N., Torrecilla, N. O., Dybov, O. G., Yudin, O., Crepin, O., Gomez, O., Sert, O. Z., Lominchar, P. L., Menendez, P., De Nardi, P., Tejedor, P., Jordan, P., Tan, P., Marsanic, P., Natalya, P., Banos, P. P., Rebasa, P., Neary, P. M., Tanis, P., Giustacchini, P., Anoldo, P., Concejo, P., Cao, P., Chandrasinghe, P., Abeyratne, P., Wang, Q., Klicks, R. 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D., Sibio, S., Ersoz, S., Pejkova, S., Altarifi, S., He, S., Malakorn, S., Meindert, S., Sumikawa, S., Parmar, S., Uranitsch, S., D'Ugo, S., Giuliani, S., Breukink, S., Lee, S. -H., Hata, T., Ishikawa, T., Akiyoshi, T., Azuma, T., Kobatake, T., Fukuzaki, T., Aiyama, T., Yamada, T., Garmanova, T., Gomez-Sanchez, T., Yamaguchi, T., De Jesus Flores, T., Usub, T., Tsuruma, T., Shimizu, T., Hristov, T. G., Van Loon, T., Funakoshi, T., Manzia, T. M., Kiyomatsu, T., Katayama, T., Akagi, T., Mizushima, T., Kazuhito, U., Elmore, U., Grossi, U., Truchalev, V. A., Rodriguez, V. S., Testa, V., Tonini, V., Celentano, V., Nekoval, V. M., Bettencourt, V., Mammadov, V., Leyva, V. A. G., Mariscal, V. G. O., Seid, V. E., Klemann, V., Turrado-Rodriguez, V., Papagni, V., Vento, V., Frering, V., Vigorita, V., Petrove, V. V., Lyadov, V., Fu, W., Mi, W., Jeong, W. K., Leclercq, W. K. G., De Sousa, X., Zhao, X., Li, X., Wang, X., Yang, X., Zhang, X., Zhen, Y., Dong, Y., Erushevich, Y., Takii, Y., Sumi, Y., Loli, Y. T., Yifat, Y. L., Shimada, Y., Nabeya, Y., Ide, Y., Wu, Y., Tsukada, Y., Miyamoto, Y., Toiyama, Y., Fujie, Y., Kaneko, Y., Mokutani, Y., Fujii, Y., Kanemitsu, Y., Medkova, Y., Chen, Y., Ruiz, Y. G., Kinugasa, Y., Sow, Z., Razzaq, Z., Wang, Z., Liu, Z., Han, Z., Tai, Z., Lai, Z., Z. Q., Ng, Dambrauskas, Z., Center of Experimental and Molecular Medicine, Graduate School, ACS - Pulmonary hypertension & thrombosis, AII - Infectious diseases, Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Surgery, Amsterdam Reproduction & Development (AR&D), Bellato V., Konishi T., Pellino G., An Y., Piciocchi A., Sensi B., Siragusa L., Khanna K., Pirozzi B.M., Franceschilli M., Campanelli M., Efetov S., Sica G.S., Kefleyesus A., Hoofwijk A.G.M., Eldaly A.S., Gonzalez A., Jawad A., Jooma A., Hafez A.M., Rubio A.V., Landaluce-Olavarria A., Wu A., Nagatsu A., Inoue A., Kanamoto A., Ouchi A., El-Hussuna A., Vazquez-Melero A., Wolthuis A.M., Peral A.M., Lozano A.C., Efremov A., Ryasantsev A.V., Di Giorgio A., Parente A., Tamburrini A., Alo A., Forero-Torres A., Vahrmeijer A.L., Varabei A., Hinojosa S., Balkan A.Z.A., Frontali A., Oleg A., Soler-Silva A., Makni A., Andre A., Cabrera A.M.G., Fernandez A.M.G., Minaya-Bravo A.M., Rodriguez-Sanchez A., Musina A.-M., Pangeni A., Zolotko A., Tonoyan A., Balla A., Belli A., Cavallaro A., Chierici A., Divizia A., Bucci A.F., Salido A.J., Morini A., Muratore A., Vignali A., Chitul A., Sebastian D.A., Pcolkins A., Shchegolev A., Hollenbeck A., Wisneski A., Iossa A., D'Amore A., Hunter A., Hesketh A.J., La Brocca A., Spinelli A., Caires A., D'Alessandro A., Correo A.F.S.L., Macri A., Navarro-Sanchez A., Pronk A., Akunc A., Mehri A., Pelta A., Papadopoulos A., Kechagias A., Rashid A., Ramazanov A., Chandio A., Kohyama A., Nishimura A., Ohkawa A., Dulskas A., Jamal A., Mariani A., Unal A.G., Karagoz A., Ozkan B.B., Salih B., Gulcu B., Pessia B., Martin-Perez B., Ielpo B., Tulelli B., Yang B., Mhamed B., Murphy B., Langenhoff B., Belevi B., Guney B., Ng C., Rueda C., Roxburgh C.S., Feo C.V., Ferrari C., Gazia C., Pratesi C., Ratto C., Santacruz C.C., Arroyave C.R.M., Macias C., Fernandez C.G., Fernandez C.C., Curtis-Martinez C., Fortmann C., Kim C., Galeano C.U., Barroso C., Baldi C., Foppa C., Formisano C., Li C., Ding C., Wang C., Iacusso C., Yang C., Pizzera C., Skias C., Chouliras C., Liakos C., Matsuda C., Wu C.-Y., Ozaslan C., Tanda C., Tommaso C.M., Dagorno C., Ramos C.P.A., Arcudi C., Coco C., Morales C.M., Ali M.Z., Lozano C.C., Sala C., Leo C.A., Scarpa C.R., Ferro C.V., Fernandez C.M., Morales-Garcia D., Nakano D., Cristian D., Hechtl D., Canovas D.T., Calabrese D., Rega D., Ferraro D., Morezzi D., Sommacale D., Brogden D., Miskovic D., Merlini D., Pertile D., Coniglio D., Zhu D., Wu D., Coletta D., Rubio D.R., Sasia D., Fillipov D., Russiello D., Dardanov D., Consten E.C.J., Smolskas E., Muttillo E.M., Jones E., Sunami E., Etienne E.-H., Chalkiadaki E., Giacomelli E., Karbovnichaya E., Ruiz-Ucar E., Guaitoli E., Samadov E., Jovine E., Treppiedi E., Vaterlini E.M., Zambaiti E., Moggia E., Coetzee E., Chisari E., D'Errico E., Ciofic E., Pena E., Kurt E., Balik E., Gunay E., Sivrikoz E., Andolfi E., Araimo E., Lucci E., Opocher E., Pinotti E., Rubino E., Reyhan E., Mazzotta E., Navarro E.B., El-Helou E., Licardie-Bolanos E., Porto E.I., Contreras E., Boerma E.-J., Cianchi F., Marino F., Uggeri F., Han F., Calculli F., Falaschi F., Ghignone F., Perrone F., Borghi F., Garcia F., Agresta F., Cananzi F.C.M., Mendoza-Moreno F., Cengiz F., Almeida F.M., Baracchi F., Carannante F., La Torre F., Fernandes F., Friedmacher F., Grama F., Carissimi F., Pecchini F., Bianco F., Colombo F., Ferrara F., Litta F., Carrano F.M., Martignoni F., Tasselli F.M., Milone F., Pata F., Sammartino F., Zambianchi F., Barragan F., Herrero F., Schlottmann F., Den Boer F.C., Pfeffer F., Fujita F., Navarra G., Herrera-Almario G., Pozzo G., Capolupo G.T., Van Ramshorst G.H., Liscia G., Gallo G., Asawa G., Wang G., Raiyani G., Beets G., Naval G.S., Jin G., Chang G.J., Saakian G., Kahane G., Borroni G., Secco G.L., Baiocchi G.L., Baronio G., Pagano G., Pattacini G.C., Lisi G., Milito G., Sinibaldi G., Serrao G., Bagaglini G., Sarro G., Brisinda G., Candilio G., Mangiameli G., Giuliani G., Martin-Martin G.P., Bodzin G., Leon G., Mackay G., Vasil G., Palmisano G., Giovanna G.M., Fernandez G.C., Steingel G.B., Zhang G., Choi G.S., Chen H., Hirose H., Kayano H., Ulgur H.S., Impellizzeri H., Ariola H., Liu H., Medina H., Miyauchi H., Takahashi H., Hayashi H., Ishikawa H., Ishida H., De Vries H., Ulman H., Kon H., Ota H., Akamatsu H., Tamagawa H., Shoji H., Egi H., Matsubara H., Miki H., Elfeki H., Lin H.-H., Giani I., Caravaca-Garcia I., Takemasa I., Angriman I., Negoi I., Volkova I., Russo I., Kronberger I.E., Shageev I., Aydin I., Mora Guzman I., Novak I., Giuliano I., Rachmuth J., Ngu J.C.-Y., Glasbey J., Stoot J., Zatecky J., Melenhorst J., Van Der Wal J.B.C., Leijtens J., Bogach J., Elliott J., De Wilt J.H.W., Han J., Cui J., Liu J., Khan J., Wirawan J.P., Zhang J., Manyari J.D.O., Doerner J., Bock J., Konsten J., Castro J.M., Grobas J.P., Pereira J., Juloski J., Laina J.L.B., Solorzano J.J., Lopez J.R.G., Li J., Watanabe J., Kwak J.-M., Hasegawa J., Hiro J., Sergey K., Zhang K., Nagahori K., Martinez K., Tokuhara K., Danno K., Uehara K., Yoshimatsu K., Ehara K., Ueda K., Suda K., Yamamoto K., Ishimaru K., Kimura K., Hirata K., Deen K., Imaizumi K., Yamada J., Tanakura K., Rida K., Sugimoto K., Kotaro K., Shi K., Okabayashi K., Hida K., Kataoka K., Hongo K., Xia K., Tseng L., Reime L., Lorenzon L., Ruano L.M., Zhou L., De Nes L., Brandariz L., Morini L., Petagna L., Ripamonti L., Martinez L.H., Pio L., Sacco L., Carvalho L., Zorcolo L., Perez-Sanchez L.E., Esparza L.H.R., Aguilar L.T., Garner M., Sugimoto M., Nagashima M., Shiozawa M., Simone M., Ferrer-Marquez M., Carvalho M., Alifano M., Arganini M., Calussi M., Catarci M., Allaix M.E., Forlin M., Milone M., Paci M., Fodor M., Antipova M., Martos M.B., Giuffrida M.C., Tabernilla M.D., Quiros M.J.A., Lemma M., Correo M.L.R.D., Malowiecka M., Bellomo M.P., Fernandez M.R., Socias M., Rizk M., Aurora M., Antolinez M.A., Ninkovic M., Giuffrida M., De Roos M.A.J., Lara M.C., Agustin M.C., Cuadrado M., Pascual M., Lemmerer M., Carlos R., Okamoto M., Miyo M., Inomata M., Ikenaga M., Tsujie M., Yasuno M., Kotake M., Sato M., Yasui M., Lavazza M., Rottoli M., Zuin M., Zuluaga M., Cervellera M., Cesari M., Zizzo M., Garino M., Ghirardi M., Montuori M., Podda M., Santarelli M., Koc M.A., Baini M., Manigrasso M., Zuolo M., Cunha M.F., Misca M., Slavchev M., Danilov M., Shigaev M., Martens M., Kobayashi M., Ren M., Ishizuka M., Hassan M.M., Siblini M., Sahloul M., Keramati M.R., Karunakaran M., Markel M., Majeed M., Younis M.U., Akin M.I., Laraibe M., Derebey M., Kendirci M., Fukunaga M., Matsubara N., Ordaz N.E.C., Samalavicius N.E., Keeratibharat N., de Angelis N., Gica N., Mariani N.M., Ramino N., Falco N., Smart N., De Korte N., Kok N.F.M., Jamieson N.B., Aberyasev N., Bruklich N., Ichikawa N., Miyoshi N., De Palma N., Figueiredo N., Torrecilla N.O., Dybov O.G., Yudin O., Crepin O., Gomez O., Sert O.Z., Lominchar P.L., Menendez P., De Nardi P., Tejedor P., Jordan P., Tan P., Marsanic P., Natalya P., Banos P.P., Rebasa P., Neary P.M., Tanis P., Giustacchini P., Anoldo P., Concejo P., Cao P., Chandrasinghe P., Abeyratne P., Wang Q., Klicks R.J., Riquelme R.F., Galli R., Gianesini R., Moorjani R.G., Deshpande R.K., Gorter R., Ledesma R.L., Ruslan R., Chhabra R., Talreja-Pelaez R., Suzuki R., Balestri R., Rosati R., Kiblawi R., Martins R., Angelico R., Tutino R., Persiani R., Pollastri R., Lopez R.G., Perez R.O., Hompes R., Lukanin R., Roser Termes Serra R., Brunaccino R., Nakanishi R., Stefan S., Hernandez S.P.S., Di Carlo S., Ingallinella S., Domoto S., Ikeda S., Mikalauskas S., Kim S.H., Mantova S., Barbuta S., Li S., Yamaguchi S., Yamagishi S., Homma S., Tsujinaka S., Yoshioka S., Mori S., Tewari S., Rayman S., Horiuchi S., Matoba S., Morita S., Yaman S., Vigna S., Testa S., Ng S., Deidda S., Cicconi S., Di Maria S., Sibio S., Ersoz S., Pejkova S., Altarifi S., He S., Malakorn S., Meindert S., Sumikawa S., Parmar S., Uranitsch S., D'ugo S., Giuliani S., Breukink S., Lee S.-H., Hata T., Ishikawa T., Akiyoshi T., Azuma T., Kobatake T., Fukuzaki T., Aiyama T., Yamada T., Garmanova T., Gomez-Sanchez T., Yamaguchi T., Flores T.D.J., Usub T., Tsuruma T., Shimizu T., Hristov T.G., Van Loon T., Funakoshi T., Manzia T.M., Kiyomatsu T., Katayama T., Kazuhito U., Elmore U., Grossi U., Truchalev V.A., Rodriguez V.S., Testa V., Tonini V., Celentano V., Bettencourt V., Mammadov V., Leyva V.A.G., Mariscal V.G.O., Seid V.E., Klemann V., Turrado-Rodriguez V., Papagni V., Vento V., Frering V., Vigorita V., Petrove V.V., Lyadov V., Fu W., Mi W., Jeong W.K., Leclercq W.K.G., De Sousa X., Zhao X., Li X., Wang X., Yang X., Zhang X., Dong Y., Erushevich Y., Takii Y., Sumi Y., Loli Y.T., Yifat Y.L., Shimada Y., Nabeya Y., Ide Y., Wu Y., Tsukada Y., Miyamoto Y., Toiyama Y., Fujie Y., Kaneko Y., Mokutani Y., Fujii Y., Kanemitsu Y., Medkova Y., Chen Y., Ruiz Y.G., Kinugasa Y., Sow Z., Razzaq Z., Wang Z., Liu Z., Han Z., Tai Z., Lai Z., Ng Z.Q., Dambrauskas Z., Bellato, 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J., La Brocca, A., Spinelli, A., Caires, A., D'Alessandro, A., Correo, A. F. S. L., Macri, A., Navarro-Sanchez, A., Pronk, A., Akunc, A., Mehri, A., Pelta, A., Papadopoulos, A., Kechagias, A., Rashid, A., Ramazanov, A., Chandio, A., Kohyama, A., Nishimura, A., Ohkawa, A., Dulskas, A., Jamal, A., Mariani, A., Unal, A. G., Karagoz, A., Ozkan, B. B., Salih, B., Gulcu, B., Pessia, B., Martin-Perez, B., Ielpo, B., Tulelli, B., Yang, B., Mhamed, B., Murphy, B., Langenhoff, B., Belevi, B., Guney, B., Ng, C., Rueda, C., Roxburgh, C. S., Feo, C. V., Ferrari, C., Gazia, C., Pratesi, C., Ratto, C., Santacruz, C. C., Arroyave, C. R. M., Macias, C., Fernandez, C. G., Fernandez, C. C., Curtis-Martinez, C., Fortmann, C., Kim, C., Galeano, C. U., Barroso, C., Baldi, C., Foppa, C., Formisano, C., Li, C., Ding, C., Wang, C., Iacusso, C., Yang, C., Pizzera, C., Skias, C., Chouliras, C., Liakos, C., Matsuda, C., Wu, C. -Y., Ozaslan, C., Tanda, C., Tommaso, C. M., Dagorno, C., Ramos, C. P. 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I., Contreras, E., Boerma, E. -J., Cianchi, F., Marino, F., Uggeri, F., Han, F., Calculli, F., Falaschi, F., Ghignone, F., Perrone, F., Borghi, F., Garcia, F., Agresta, F., Cananzi, F. C. M., Mendoza-Moreno, F., Cengiz, F., Almeida, F. M., Baracchi, F., Carannante, F., La Torre, F., Fernandes, F., Friedmacher, F., Grama, F., Carissimi, F., Pecchini, F., Bianco, F., Colombo, F., Ferrara, F., Litta, F., Carrano, F. M., Martignoni, F., Tasselli, F. M., Milone, F., Pata, F., Sammartino, F., Zambianchi, F., Barragan, F., Herrero, F., Schlottmann, F., Den Boer, F. C., Pfeffer, F., Fujita, F., Navarra, G., Herrera-Almario, G., Pozzo, G., Capolupo, G. T., Van Ramshorst, G. H., Liscia, G., Gallo, G., Asawa, G., Wang, G., Raiyani, G., Beets, G., Naval, G. S., Jin, G., Chang, G. J., Saakian, G., Kahane, G., Borroni, G., Secco, G. L., Baiocchi, G. L., Baronio, G., Pagano, G., Pattacini, G. C., Lisi, G., Milito, G., Sinibaldi, G., Serrao, G., Bagaglini, G., Sarro, G., Brisinda, G., Candilio, G., Mangiameli, G., Giuliani, G., Martin-Martin, G. P., Bodzin, G., Leon, G., Mackay, G., Vasil, G., Palmisano, G., Giovanna, G. M., Fernandez, G. C., Steingel, G. B., Zhang, G., Choi, G. S., Chen, H., Hirose, H., Kayano, H., Ulgur, H. S., Impellizzeri, H., Ariola, H., Liu, H., Medina, H., Miyauchi, H., Takahashi, H., Hayashi, H., Ishikawa, H., Ishida, H., De Vries, H., Ulman, H., Kon, H., Ota, H., Akamatsu, H., Tamagawa, H., Shoji, H., Egi, H., Matsubara, H., Miki, H., Elfeki, H., Lin, H. -H., Giani, I., Caravaca-Garcia, I., Takemasa, I., Angriman, I., Negoi, I., Volkova, I., Russo, I., Kronberger, I. E., Shageev, I., Aydin, I., Guzman, I. M., Novak, I., Giuliano, I., Rachmuth, J., Ngu, J. C. -Y., Glasbey, J., Stoot, J., Zatecky, J., Melenhorst, J., Van Der Wal, J. B. C., Leijtens, J., Bogach, J., Elliott, J., De Wilt, J. H. W., Han, J., Cui, J., Liu, J., Khan, J., Wirawan, J. 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I., Laraibe, M., Derebey, M., Kendirci, M., Fukunaga, M., Matsubara, N., Ordaz, N. E. C., Samalavicius, N. E., Keeratibharat, N., de Angelis, N., Gica, N., Mariani, N. M., Ramino, N., Falco, N., Smart, N., De Korte, N., Kok, N. F. M., Jamieson, N. B., Aberyasev, N., Bruklich, N., Ichikawa, N., Miyoshi, N., De Palma, N., Figueiredo, N., Torrecilla, N. O., Dybov, O. G., Yudin, O., Crepin, O., Gomez, O., Sert, O. Z., Lominchar, P. L., Menendez, P., De Nardi, P., Tejedor, P., Jordan, P., Tan, P., Marsanic, P., Natalya, P., Banos, P. P., Rebasa, P., Neary, P. M., Tanis, P., Giustacchini, P., Anoldo, P., Concejo, P., Cao, P., Chandrasinghe, P., Abeyratne, P., Wang, Q., Klicks, R. J., Riquelme, R. F., Galli, R., Gianesini, R., Moorjani, R. G., Deshpande, R. K., Gorter, R., Ledesma, R. L., Ruslan, R., Chhabra, R., Talreja-Pelaez, R., Suzuki, R., Balestri, R., Rosati, R., Kiblawi, R., Martins, R., Angelico, R., Tutino, R., Persiani, R., Pollastri, R., Lopez, R. G., Perez, R. O., Hompes, R., Lukanin, R., Roser Termes Serra, R., Brunaccino, R., Nakanishi, R., Stefan, S., Hernandez, S. P. S., Di Carlo, S., Ingallinella, S., Domoto, S., Ikeda, S., Mikalauskas, S., Kim, S. H., Mantova, S., Barbuta, S., Li, S., Yamaguchi, S., Yamagishi, S., Homma, S., Tsujinaka, S., Yoshioka, S., Mori, S., Tewari, S., Rayman, S., Horiuchi, S., Matoba, S., Morita, S., Yaman, S., Vigna, S., Testa, S., Ng, S., Deidda, S., Cicconi, S., Di Maria, S., Sibio, S., Ersoz, S., Pejkova, S., Altarifi, S., He, S., Malakorn, S., Meindert, S., Sumikawa, S., Parmar, S., Uranitsch, S., D'Ugo, S., Giuliani, S., Breukink, S., Lee, S. -H., Hata, T., Ishikawa, T., Akiyoshi, T., Azuma, T., Kobatake, T., Fukuzaki, T., Aiyama, T., Yamada, T., Garmanova, T., Gomez-Sanchez, T., Yamaguchi, T., Flores, T. D. J., Usub, T., Tsuruma, T., Shimizu, T., Hristov, T. G., Van Loon, T., Funakoshi, T., Manzia, T. M., Kiyomatsu, T., Katayama, T., Kazuhito, U., Elmore, U., Grossi, U., Truchalev, V. A., Rodriguez, V. S., Testa, V., Tonini, V., Celentano, V., Bettencourt, V., Mammadov, V., Leyva, V. A. G., Mariscal, V. G. O., Seid, V. E., Klemann, V., Turrado-Rodriguez, V., Papagni, V., Vento, V., Frering, V., Vigorita, V., Petrove, V. V., Lyadov, V., Fu, W., Mi, W., Jeong, W. K., Leclercq, W. K. G., De Sousa, X., Zhao, X., Li, X., Wang, X., Yang, X., Zhang, X., Dong, Y., Erushevich, Y., Takii, Y., Sumi, Y., Loli, Y. T., Yifat, Y. L., Shimada, Y., Nabeya, Y., Ide, Y., Wu, Y., Tsukada, Y., Miyamoto, Y., Toiyama, Y., Fujie, Y., Kaneko, Y., Mokutani, Y., Fujii, Y., Kanemitsu, Y., Medkova, Y., Chen, Y., Ruiz, Y. G., Kinugasa, Y., Sow, Z., Razzaq, Z., Wang, Z., Liu, Z., Han, Z., Tai, Z., Lai, Z., Ng, Z. Q., Dambrauskas, Z., Mora Guzman, I., Rinha, R., Robotics and image-guided minimally-invasive surgery (ROBOTICS), Bellato, V, Konishi, T, Pellino, G, An, Y, Piciocchi, A, Sensi, B, Siragusa, L, Khanna, K, Pirozzi, B, Franceschilli, M, Campanelli, M, Efetov, S, Sica, G, Kefleyesus, A, Hoofwijk, A, Eldaly, A, Gonzalez, A, Jawad, A, Jooma, A, Hafez, A, Rubio, A, Landaluce-Olavarria, A, Wu, A, Nagatsu, A, Inoue, A, Kanamoto, A, Ouchi, A, El-Hussuna, A, Vazquez-Melero, A, Wolthuis, A, Peral, A, Lozano, A, Efremov, A, Ryasantsev, A, Di Giorgio, A, Parente, A, Tamburrini, A, Alo, A, Forero-Torres, A, Vahrmeijer, A, Varabei, A, Hinojosa, S, Balkan, A, Frontali, A, Oleg, A, Soler-Silva, A, Makni, A, Andre, A, Cabrera, A, Fernandez, A, Minaya-Bravo, A, Rodriguez-Sanchez, A, Musina, A, Pangeni, A, Zolotko, A, Tonoyan, A, Balla, A, Belli, A, Cavallaro, A, Chierici, A, Divizia, A, Bucci, A, Salido, A, Morini, A, Muratore, A, Vignali, A, Chitul, A, Sebastian, D, Pcolkins, A, Shchegolev, A, Hollenbeck, A, Wisneski, A, Iossa, A, D'Amore, A, Hunter, A, Hesketh, A, La Brocca, A, Spinelli, A, Caires, A, D'Alessandro, A, Correo, A, Macri, A, Navarro-Sanchez, A, Pronk, A, Akunc, A, Mehri, A, Pelta, A, Papadopoulos, A, Kechagias, A, Rashid, A, Ramazanov, A, Chandio, A, Kohyama, A, Nishimura, A, Ohkawa, A, Dulskas, A, Jamal, A, Mariani, A, Unal, A, Karagoz, A, Ozkan, B, Salih, B, Gulcu, B, Pessia, B, Martin-Perez, B, Ielpo, B, Tulelli, B, Yang, B, Mhamed, B, Murphy, B, Langenhoff, B, Belevi, B, Guney, B, Ng, C, Rueda, C, Roxburgh, C, Feo, C, Ferrari, C, Gazia, C, Pratesi, C, Ratto, C, Santacruz, C, Arroyave, C, Macias, C, Fernandez, C, Curtis-Martinez, C, Fortmann, C, Kim, C, Galeano, C, Barroso, C, Baldi, C, Foppa, C, Formisano, C, Li, C, Ding, C, Wang, C, Iacusso, C, Yang, C, Pizzera, C, Skias, C, Chouliras, C, Liakos, C, Matsuda, C, Wu, C, Ozaslan, C, Tanda, C, Tommaso, C, Dagorno, C, Ramos, C, Arcudi, C, Coco, C, Morales, C, Ali, M, Lozano, C, Sala, C, Leo, C, Scarpa, C, Ferro, C, Morales-Garcia, D, Nakano, D, Cristian, D, Hechtl, D, Canovas, D, Calabrese, D, Rega, D, Ferraro, D, Morezzi, D, Sommacale, D, Brogden, D, Miskovic, D, Merlini, D, Pertile, D, Coniglio, D, Zhu, D, Wu, D, Coletta, D, Rubio, D, Sasia, D, Fillipov, D, Russiello, D, Dardanov, D, Consten, E, Smolskas, E, Muttillo, E, Jones, E, Sunami, E, Etienne, E, Chalkiadaki, E, Giacomelli, E, Karbovnichaya, E, Ruiz-Ucar, E, Guaitoli, E, Samadov, E, Jovine, E, Treppiedi, E, Vaterlini, E, Zambaiti, E, Moggia, E, Coetzee, E, Chisari, E, D'Errico, E, Ciofic, E, Pena, E, Kurt, E, Balik, E, Gunay, E, Sivrikoz, E, Andolfi, E, Araimo, E, Lucci, E, Opocher, E, Pinotti, E, Rubino, E, Reyhan, E, Mazzotta, E, Navarro, E, El-Helou, E, Licardie-Bolanos, E, Porto, E, Contreras, E, Boerma, E, Cianchi, F, Marino, F, Uggeri, F, Han, F, Calculli, F, Falaschi, F, Ghignone, F, Perrone, F, Borghi, F, Garcia, F, Agresta, F, Cananzi, F, Mendoza-Moreno, F, Cengiz, F, Almeida, F, Baracchi, F, Carannante, F, La Torre, F, Fernandes, F, Friedmacher, F, Grama, F, Carissimi, F, Pecchini, F, Bianco, F, Colombo, F, Ferrara, F, Litta, F, Carrano, F, Martignoni, F, Tasselli, F, Milone, F, Pata, F, Sammartino, F, Zambianchi, F, Barragan, F, Herrero, F, Schlottmann, F, Den Boer, F, Pfeffer, F, Fujita, F, Navarra, G, Herrera-Almario, G, Pozzo, G, Capolupo, G, Van Ramshorst, G, Liscia, G, Gallo, G, Asawa, G, Wang, G, Raiyani, G, Beets, G, Naval, G, Jin, G, Chang, G, Saakian, G, Kahane, G, Borroni, G, Secco, G, Baiocchi, G, Baronio, G, Pagano, G, Pattacini, G, Lisi, G, Milito, G, Sinibaldi, G, Serrao, G, Bagaglini, G, Sarro, G, Brisinda, G, Candilio, G, Mangiameli, G, Giuliani, G, Martin-Martin, G, Bodzin, G, Leon, G, Mackay, G, Vasil, G, Palmisano, G, Giovanna, G, Fernandez, G, Steingel, G, Zhang, G, Choi, G, Chen, H, Hirose, H, Kayano, H, Ulgur, H, Impellizzeri, H, Ariola, H, Liu, H, Medina, H, Miyauchi, H, Takahashi, H, Hayashi, H, Ishikawa, H, Ishida, H, De Vries, H, Ulman, H, Kon, H, Ota, H, Akamatsu, H, Tamagawa, H, Shoji, H, Egi, H, Matsubara, H, Miki, H, Elfeki, H, Lin, H, Giani, I, Caravaca-Garcia, I, Takemasa, I, Angriman, I, Negoi, I, Volkova, I, Russo, I, Kronberger, I, Shageev, I, Aydin, I, Mora Guzman, I, Novak, I, Giuliano, I, Rachmuth, J, Ngu, J, Glasbey, J, Stoot, J, Zatecky, J, Melenhorst, J, Van Der Wal, J, Leijtens, J, Bogach, J, Elliott, J, De Wilt, J, Han, J, Cui, J, Liu, J, Khan, J, Wirawan, J, Zhang, J, Manyari, J, Doerner, J, Bock, J, Konsten, J, Castro, J, Grobas, J, Pereira, J, Juloski, J, Laina, J, Solorzano, J, Lopez, J, Li, J, Watanabe, J, Kwak, J, Hasegawa, J, Hiro, J, Sergey, K, Zhang, K, Nagahori, K, Martinez, K, Tokuhara, K, Danno, K, Uehara, K, Yoshimatsu, K, Ehara, K, Ueda, K, Suda, K, Yamamoto, K, Ishimaru, K, Kimura, K, Hirata, K, Deen, K, Imaizumi, K, Yamada, J, Tanakura, K, Rida, K, Sugimoto, K, Kotaro, K, Shi, K, Okabayashi, K, Hida, K, Kataoka, K, Hongo, K, Xia, K, Tseng, L, Reime, L, Lorenzon, L, Ruano, L, Zhou, L, De Nes, L, Brandariz, L, Morini, L, Petagna, L, Ripamonti, L, Martinez, L, Pio, L, Sacco, L, Carvalho, L, Zorcolo, L, Perez-Sanchez, L, Esparza, L, Aguilar, L, Garner, M, Sugimoto, M, Nagashima, M, Shiozawa, M, Simone, M, Ferrer-Marquez, M, Carvalho, M, Alifano, M, Arganini, M, Calussi, M, Catarci, M, Allaix, M, Forlin, M, Milone, M, Paci, M, Fodor, M, Antipova, M, Martos, M, Giuffrida, M, Tabernilla, M, Quiros, M, Lemma, M, Correo, M, Malowiecka, M, Bellomo, M, Fernandez, M, Socias, M, Rizk, M, Aurora, M, Antolinez, M, Ninkovic, M, De Roos, M, Lara, M, Agustin, M, Cuadrado, M, Pascual, M, Lemmerer, M, Carlos, R, Okamoto, M, Miyo, M, Inomata, M, Ikenaga, M, Tsujie, M, Yasuno, M, Kotake, M, Sato, M, Yasui, M, Lavazza, M, Rottoli, M, Zuin, M, Zuluaga, M, Cervellera, M, Cesari, M, Zizzo, M, Garino, M, Ghirardi, M, Montuori, M, Podda, M, Santarelli, M, Koc, M, Baini, M, Manigrasso, M, Zuolo, M, Cunha, M, Misca, M, Slavchev, M, Danilov, M, Shigaev, M, Martens, M, Kobayashi, M, Ren, M, Ishizuka, M, Hassan, M, Siblini, M, Sahloul, M, Keramati, M, Karunakaran, M, Markel, M, Majeed, M, Younis, M, Akin, M, Laraibe, M, Derebey, M, Kendirci, M, Fukunaga, M, Matsubara, N, Ordaz, N, Samalavicius, N, Keeratibharat, N, de Angelis, N, Gica, N, Mariani, N, Ramino, N, Falco, N, Smart, N, De Korte, N, Kok, N, Jamieson, N, Aberyasev, N, Bruklich, N, Ichikawa, N, Miyoshi, N, De Palma, N, Figueiredo, N, Torrecilla, N, Dybov, O, Yudin, O, Crepin, O, Gomez, O, Sert, O, Lominchar, P, Menendez, P, De Nardi, P, Tejedor, P, Jordan, P, Tan, P, Marsanic, P, Natalya, P, Banos, P, Rebasa, P, Neary, P, Tanis, P, Giustacchini, P, Anoldo, P, Concejo, P, Cao, P, Chandrasinghe, P, Abeyratne, P, Wang, Q, Klicks, R, Riquelme, R, Galli, R, Gianesini, R, Moorjani, R, Deshpande, R, Gorter, R, Ledesma, R, Ruslan, R, Chhabra, R, Talreja-Pelaez, R, Suzuki, R, Balestri, R, Rosati, R, Kiblawi, R, Martins, R, Angelico, R, Tutino, R, Persiani, R, Pollastri, R, Lopez, R, Perez, R, Hompes, R, Lukanin, R, Roser Termes Serra, R, Brunaccino, R, Nakanishi, R, Stefan, S, Hernandez, S, Di Carlo, S, Ingallinella, S, Domoto, S, Ikeda, S, Mikalauskas, S, Kim, S, Mantova, S, Barbuta, S, Li, S, Yamaguchi, S, Yamagishi, S, Homma, S, Tsujinaka, S, Yoshioka, S, Mori, S, Tewari, S, Rayman, S, Horiuchi, S, Matoba, S, Morita, S, Yaman, S, Vigna, S, Testa, S, Ng, S, Deidda, S, Cicconi, S, Di Maria, S, Sibio, S, Ersoz, S, Pejkova, S, Altarifi, S, He, S, Malakorn, S, Meindert, S, Sumikawa, S, Parmar, S, Uranitsch, S, D'Ugo, S, Giuliani, S, Breukink, S, Lee, S, Hata, T, Ishikawa, T, Akiyoshi, T, Azuma, T, Kobatake, T, Fukuzaki, T, Aiyama, T, Yamada, T, Garmanova, T, Gomez-Sanchez, T, Yamaguchi, T, Flores, T, Usub, T, Tsuruma, T, Shimizu, T, Hristov, T, Van Loon, T, Funakoshi, T, Manzia, T, Kiyomatsu, T, Katayama, T, Kazuhito, U, Elmore, U, Grossi, U, Truchalev, V, Rodriguez, V, Testa, V, Tonini, V, Celentano, V, Bettencourt, V, Mammadov, V, Leyva, V, Mariscal, V, Seid, V, Klemann, V, Turrado-Rodriguez, V, Papagni, V, Vento, V, Frering, V, Vigorita, V, Petrove, V, Lyadov, V, Fu, W, Mi, W, Jeong, W, Leclercq, W, De Sousa, X, Zhao, X, Li, X, Wang, X, Yang, X, Zhang, X, Dong, Y, Erushevich, Y, Takii, Y, Sumi, Y, Loli, Y, Yifat, Y, Shimada, Y, Nabeya, Y, Ide, Y, Wu, Y, Tsukada, Y, Miyamoto, Y, Toiyama, Y, Fujie, Y, Kaneko, Y, Mokutani, Y, Fujii, Y, Kanemitsu, Y, Medkova, Y, Chen, Y, Ruiz, Y, Kinugasa, Y, Sow, Z, Razzaq, Z, Wang, Z, Liu, Z, Han, Z, Tai, Z, Lai, Z, Ng, Z, and Dambrauskas, Z
Subjects: 2019-20 coronavirus outbreak, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), covid-19, pandemic, surgery, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Settore MED/18 - CHIRURGIA GENERALE, MEDLINE, COVID-19. Global surgery, Asymptomatic, COVID-19, Critical Pathways, Cross Infection, Cross-Sectional Studies, Health Care Surveys, Humans, Pandemics, Postoperative Complications, SARS-CoV-2, Surgical Procedures, Operative, Asymptomatic Infections, COVID-19, Critical Pathways, Cross Infection, Cross-Sectional Studies, Health Care Surveys, Humans, Pandemics, Postoperative Complications, SARS-CoV-2, Surgical Procedures, Operative, Asymptomatic Infections, NO, surgery, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], Pandemic, Correspondence, medicine, LS7_4, COVID, Surgical Procedures, Critical pathways, business.industry, pandemic, Surgical procedures, Operative, Settore MED/18, covid 19, surgical practice, COVID-19 - surgery, Emergency medicine, medicine.symptom, business
Abstract: The rapid spread of COVID-19 has changed the global surgical care. Patients infected with COVID-19 may present without typical symptoms, and such asymptomatic patients may potentially trigger in-hospital outbreaks by transmitting the disease to health care providers and other hospitalized patients. Further, asymptomatic COVID-19 patients have worse postop- erative outcomes with an unexpectedly high morbidity and mortality, reaching 20⋅5 per cent deaths. However, we do not have objective global data on this issue. In an attempt to clarify the current global surgical practice under the COVID-19 pandemic particularly focusing on the preoperative screening of asymptomatic COVID-19 patients, we conducted a cross-sectional online survey on surgical practice. The survey was administered to surgeons worldwide through international surgical societies, social media and personal contacts dur- ing 2 April to 8 April. The results were analyzed by country’s cumulative deaths number by 8 April, 2020 (high risk, >5000; intermediate risk, 100-5000; low risk
Published: 2020

28. Accuracy of genomic prediction of complex traits in sugarcane

Author: Loan T. Nguyen, Ben J. Hayes, Priya Joyce, Tony Cavallaro, Emily Deomano, Jenny Yue, Felicity Atkin, Kai P. Voss-Fels, Xianming Wei, Karen S. Aitken, and Elizabeth M. Ross
Subjects: 0106 biological sciences, education.field_of_study, business.industry, Population, Plant genetics, General Medicine, Quantitative trait locus, Biology, Flowering time, 01 natural sciences, Biotechnology, Genetic marker, Genetic gain, Genetics, education, business, Agronomy and Crop Science, Hectare, Fibre content, 010606 plant biology & botany
Abstract: Complex traits in sugarcane can be accurately predicted using genome-wide DNA markers. Genomic single-step prediction is an attractive method for genomic selection in commercial breeding programs. Sugarcane breeding programs have achieved up to 1% genetic gain in key traits such as tonnes of cane per hectare (TCH), commercial cane sugar (CCS) and Fibre content over the past decades. Here, we assess the potential of genomic selection to increase the rate of genetic gain for these traits by deriving genomic estimated breeding values (GEBVs) from a reference population of 3984 clones genotyped for 26 K SNP. We evaluated the three different genomic prediction approaches GBLUP, genomic single step (GenomicSS), and BayesR. GenomicSS combining pedigree and SNP information from historic and recent breeding programs achieved the most accurate predictions for most traits (0.3–0.44). This method is attractive for routine genetic evaluation because it requires relatively little modification to the existing evaluation and results in breeding value estimates for all individuals, not only those genotyped. Adding information from early-stage trials added up to 5% accuracy for CCS and Fibre, but 0% for TCH, reflecting the importance of competition effects for TCH. These GEBV accuracies are sufficiently high that, combined with the right breeding strategy, a doubling of the rate of genetic gain could be achieved. We also assessed the flowering traits days to flowering, gender and pollen viability and found high heritabilities of 0.57, 0.78 and 0.72, respectively. The GEBV accuracies indicated that genomic selection could be used to improve these traits. This could open new avenues for breeders to manage their breeding programs, for example, by synchronising flowering time and selecting males with high pollen viability.
Published: 2021
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29. Evaluación de lesiones de la columna cervical en pacientes con politraumatismos, en el Servicio de Urgencias

Author: Alejandro Griglio, Romina Cavallaro, Sergio Sánchez, Sofía Frank, Alberto Tulli, and Federico Koll
Subjects: medicine.medical_specialty, Emergency unit, medicine.diagnostic_test, business.industry, Radiography, 030208 emergency & critical care medicine, Physical examination, General Medicine, Semiology, Cervical spine, Palpation, 03 medical and health sciences, 0302 clinical medicine, medicine, 030212 general & internal medicine, Radiology, False positive rate, Medical diagnosis, business
Abstract: Introducción: Tradicionalmente se ha recurrido al examen clínico-neurológico y a los estudios por imágenes para identificar lesiones de la columna cervical en pacientes con politraumatismos. En diferentes centros de trauma, la evaluación inicial de estos pacientes incluye un examen clínico-neurológico más radiografías obligatorias, independientemente de una semiología normal, en un paciente despierto y consciente. Esto se debe a la creencia de que el examen clínico es insuficiente para detectar estas lesiones. Materiales y Métodos: Se trata de un estudio transversal y observacional para determinar la sensibilidad y la especificidad de la evaluación clínica para el diagnóstico de lesiones de la columna cervical comparadas con las de los estudios por imágenes, en un período de 22 meses, en un Servicio de Urgencias. Resultados: Durante este período, se asistió a 127 pacientes. El examen físico neurológico fue normal en 101 pacientes, ninguno tenía una lesión constatada en las radiografías o las imágenes tomográficas. Veintiséis pacientes refirieron dolor a la palpación de las apófisis espinosas; en 6 de ellos, se constató una lesión de la columna cervical con la tomografía. La sensibilidad del examen físico fue del 100% y la especificidad, del 83%. La tasa de falsos positivos fue del 17% y no se registró ningún falso negativo. Conclusiones: Los datos de este estudio demuestran que la mayoría de los estudios por imágenes, radiografías o tomografías computarizadas podrían disminuirse, sin perder la sensibilidad del diagnóstico de lesiones de la columna cervical, reduciendo así los costos de la atención.Nivel de Evidencia: IV
Published: 2021
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30. Neonatal respiratory and cardiac ECMO in Europe

Author: Francesco Macchini, Giacomo Cavallaro, Fabio Mosca, Antonio Amodeo, Ilaria Amodeo, Matteo Di Nardo, Shady Kamel, and Genny Raffaeli
Subjects: medicine.medical_specialty, medicine.medical_treatment, Review, Disease, Anticoagulation, 03 medical and health sciences, Extracorporeal Membrane Oxygenation, Neonate, 0302 clinical medicine, 030225 pediatrics, Epidemiology, medicine, Extracorporeal membrane oxygenation, Humans, Respiratory ECMO, 030212 general & internal medicine, Intensive care medicine, ECMO management, Survival rate, Critically ill, business.industry, Follow-up, Infant, Newborn, Congenital diaphragmatic hernia, Developmental Hemostasis, medicine.disease, Europe, Survival Rate, surgical procedures, operative, Respiratory failure, Life support, Pediatrics, Perinatology and Child Health, ECMO, Hernias, Diaphragmatic, Congenital, Respiratory Insufficiency, business, Cardiac ECMO, ECMO complications
Abstract: Neonatal extracorporeal membrane oxygenation (ECMO) is a life-saving procedure for critically ill neonates suffering from a potentially reversible disease, causing severe cardiac and/or respiratory failure and refractory to maximal conventional management. Since the 1970s, technology, management, and clinical applications of neonatal ECMO have changed. Pulmonary diseases still represent the principal neonatal diagnosis, with an overall 74% survival rate, and up to one-third of cases are due to congenital diaphragmatic hernia. The overall survival rate in cardiac ECMO is lower, with congenital heart defect representing the main indication. This review provides an overview of the available evidence in the field of neonatal ECMO. We will address the changing epidemiology, basic principles, technologic advances in circuitry, and monitoring, and deliver a current multidisciplinary management framework, focusing on ECMO applications, complications, and long-term morbidities. Lastly, areas for further research will be highlighted.Conclusions: ECMO is a life support with a potential impact on long-term patients' outcomes. In the next years, advances in knowledge, technology, and expertise may push neonatal ECMO boundaries towards more premature and increasingly complex infants, with the final aim to reduce the burden of ECMO-related complications and improve overall patients' outcomes. What is Known: • ECMO is a life-saving option in newborns with refractory respiratory and/or cardiac failure. • The multidisciplinary ECMO management is challenging and may expose neonates to complications with an impact on long-term outcomes. What is New: • Advances in technology and biomaterials will improve neonatal ECMO management and, eventually, the long-term outcome of these complex patients. • Experimental models of artificial placenta and womb technology are under investigation and may provide clinical translation and future research opportunities.
Published: 2021
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31. View-Action Representation Learning for Active First-Person Vision

Author: Andrea Cavallaro and Changjae Oh
Subjects: Artificial neural network, Computer science, business.industry, Representation (systemics), Sensory system, 02 engineering and technology, Visualization, Ranking (information retrieval), Action (philosophy), 0202 electrical engineering, electronic engineering, information engineering, Media Technology, Feature (machine learning), 020201 artificial intelligence & image processing, Computer vision, State (computer science), Artificial intelligence, Electrical and Electronic Engineering, business, Feature learning
Abstract: In visual navigation, a moving agent equipped with a camera is traditionally controlled by an input action and the estimation of the features from a sensory state (i.e. the camera view) is treated as a pre-processing step to perform high-level vision tasks. In this paper, we present a representation learning approach that, instead, considers both state and action as inputs. We condition the encoded feature from the state transition network on the action that changes the view of the camera, thus describing the scene more effectively. Specifically, we introduce an action representation module that generates decoded higher dimensional representations from an input action to increase the representational power. We then fuse the output from the action representation module with the intermediate response of the state transition network that predicts the future state. To enhance the discrimination capability among predictions from different input actions, we further introduce triplet ranking loss and $N$ -tuplet loss functions, which in turn can be integrated with the regression loss. We demonstrate the proposed representation learning approach in reinforcement and imitation learning-based mapless navigation tasks, where the camera agent learns to navigate only through the view of the camera and the performed action, without external information.
Published: 2021
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32. Incremental diagnostic value of color-coded virtual non-calcium dual-energy CT for the assessment of traumatic bone marrow edema of the scaphoid

Author: Christian Booz, Thomas J. Vogl, Marco Cavallaro, Tommaso D'Angelo, Felix C. Müller, Vitali Koch, Lukas Lenga, Ibrahim Yel, Christoph Mader, Moritz H. Albrecht, Giuseppe Cicero, Silvio Mazziotti, Kasper Kjærulf Gosvig, Julian L. Wichmann, and Simon S. Martin
Subjects: Adult, Male, medicine.medical_specialty, Wrist, Sensitivity and Specificity, 030218 nuclear medicine & medical imaging, Multidetector computed tomography, Young Adult, 03 medical and health sciences, Magnetic resonance imaging, 0302 clinical medicine, Bone Marrow, Hounsfield scale, Scaphoid, medicine, Edema, Humans, Radiology, Nuclear Medicine and imaging, Aged, Retrospective Studies, Neuroradiology, Aged, 80 and over, Scaphoid Bone, medicine.diagnostic_test, Receiver operating characteristic, business.industry, Ultrasound, Interventional radiology, Retrospective cohort study, General Medicine, Middle Aged, Fracture, medicine.anatomical_structure, Bone marrow edema, 030220 oncology & carcinogenesis, Calcium, Female, Radiology, Tomography, X-Ray Computed, business
Abstract: To investigate the diagnostic accuracy of color-coded dual-energy CT virtual non-calcium (VNCa) reconstructions for the assessment of bone marrow edema (BME) of the scaphoid in patients with acute wrist trauma. Our retrospective study included data from 141 patients (67 women, 74 men; mean age 43 years, range 19–80 years) with acute wrist trauma who had undergone third-generation dual-source dual-energy CT and 3-T MRI within 7 days. Eight weeks after assessment of conventional grayscale dual-energy CT scans for the presence of fractures, corresponding color-coded VNCa reconstructions were independently analyzed by the same six radiologists for the presence of BME. CT numbers on VNCa reconstructions were evaluated by a seventh radiologist. Consensus reading of MRI series by two additional radiologists served as the reference standard. MRI depicted 103 scaphoideal zones with BME in 76 patients. On qualitative analysis, VNCa images yielded high overall sensitivity (580/618 [94%]), specificity (1880/1920 [98%]), and accuracy (2460/2538 [97%]) for assessing BME as compared with MRI as reference standard. The interobserver agreement was excellent (κ = 0.98). CT numbers derived from VNCa images were significantly different in zones with and without edema (p
Published: 2021
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33. Autism, Therapy and COVID-19

Author: Alessandro Frolli, Francesca Felicia Operto, Giulio Corrivetti, Antonella Cavallaro, Emanuele Mingione, Ferdinando Russo, Maria Carla Ricci, and Luana Sergi
Subjects: 050103 clinical psychology, Pediatrics, medicine.medical_specialty, stereotypes, behaviors, Coronavirus disease 2019 (COVID-19), medicine.medical_treatment, autism, lcsh:Medicine, Article, 03 medical and health sciences, 0302 clinical medicine, children, 030225 pediatrics, Intervention (counseling), medicine, 0501 psychology and cognitive sciences, Applied behavior analysis, communication, business.industry, lcsh:R, 05 social sciences, Socialization, quarantine, lcsh:RJ1-570, COVID-19, lcsh:Pediatrics, medicine.disease, ABA, Autism spectrum disorder, Parent training, Autism, business, Inclusion (education)
Abstract: While numerous treatments for ASD are available, intervention based on the principles and procedures of Applied Behavior Analysis (ABA) has garnered substantial scientific support. In this study we evaluated the effects of the lockdown during the COVID-19 pandemic outbreak, followed by quarantine provisions and during the three months after the resumption of activities. The study was conducted on a group of children taking part on a ABA-based intervention funded by the Local Health Authority (ASL) of the province of Caserta. In this study we considered a sample of 88 children who had been diagnosed with Autism Spectrum Disorder, aged between 18 and 30 months. The following inclusion criteria were observed: age at the time of diagnosis less than 30 months, absence of other neurological, genetic, or sensorineural pathologies, and severity level 1 measured by symptoms evaluation based on the ADOS 2 module T (used for diagnosis). During the lockdown children experienced improvements in communication, socialization, and personal autonomy. During the three months after the ABA treatment, the acquired skills were maintained but no significant improvement was demonstrated. In this study, we describe how parent training was significant in avoiding delays in the generalization of socially significant behaviors, following the drastic interruption of the treatment in this group of children.
Published: 2021
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34. Metrics Used to Quantify Fecal Incontinence and Constipation

Author: Liliana Bordeianou, Paul M Cavallaro, and Cameron W. Hunt
Subjects: medicine.medical_specialty, Research use, Constipation, business.industry, Gastroenterology, Review article, Pelvic Floor Disorders, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Clinical decision making, 030220 oncology & carcinogenesis, Physical therapy, Medicine, Fecal incontinence, 030211 gastroenterology & hepatology, Surgery, medicine.symptom, business
Abstract: While fecal incontinence and constipation can be measured through physiological testing, the subjective experience of severity and impact on health-related quality of life lead to both being most effectively captured through patient-reported measures. Patient-reported measures of severity and impact help to determine baseline symptoms, guide clinical decision making, and compare various treatments. Here, we take pause to review the psychometric qualities that make effective instruments, and discuss some of the most commonly used instruments along with the reasons behind their use. In addition, we highlight the benefits of a standardized instrument designed to evaluate the major symptoms of patients presenting with pelvic floor disorders (including fecal incontinence and constipation). Ultimately, we aim to provide guidance in choosing appropriate instruments for clinical and research use.
Published: 2021
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35. Is there a relationship between length of resection and lymph-node ratio in colorectal cancer?

Author: Emanuele Lo Menzo, Alessandro Cappellani, Salvatore Lo Bianco, Francesco Cardì, Maria Di Vita, Andrea Cavallaro, Antonio Zanghì, and Serena Curella Botta
Subjects: medicine.medical_specialty, Colorectal cancer, colorectal cancer, Gastroenterology, lymph-node ratio, resection length, prognostic value, Resection, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Statistical significance, medicine, In patient, Lymph node, AcademicSubjects/MED00260, business.industry, Confounding, Retrospective cohort study, Original Articles, medicine.disease, medicine.anatomical_structure, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Lymph, business
Abstract: Background The prognosis of colorectal cancer depends on the number of positive lymph nodes (LN+) and the total number of lymph nodes resected (rLN). This represents the lymph-node ratio (LNR). The aim of our study is to assess how the length of the resected specimen (RL) influences the prognostic values of the LNR. Methods We conducted a retrospective study of all the patients operated on for colorectal cancer from 2000 to 2015 at our institution. Pathology details were analysed. The total number of rLN, the number of LN+, and the LNR were calculated and measured against the RL. The receiver-operating characteristic (ROC) curve of patients with LN+ was calculated. Results Of the 670 patients included in our study, 337 were men (50.3%) and the mean age was 69.2 years. The correlation with prognosis of the LNR is greater than that of the LNR adjusted to RL (LNR/RL), both in subjects with positive nodes (n = 312) and in all cases (n = 670). The LNR presents a higher prognostic value than LNR/RL and RL in patients with LN+ except for metastatic recurrence, for which the predictive value appears slightly higher for LNR/RL. The statistical significance of the maximal divergence in Kaplan–Meier survival plots was demonstrated for the LNR (P = 0.043), not for LNR/RL (P = 0.373) and RL alone (P = 0.314). Conclusion An increase in RL causes an increase in the number of harvested lymph nodes without affecting the number of LN+, thus representing a confounding factor that could alter the prognostic value of the LNR. Prospective larger-scale studies are needed to confirm these findings.
Published: 2020
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36. Institutional barriers to participation in EU framework programs: contrasting the Swiss and UK cases

Author: Benedetto Lepori and Marco Cavallaro
Subjects: Public economics, Higher education, business.industry, European research, 05 social sciences, Control (management), General Social Sciences, Library and Information Sciences, Difference in differences, 0506 political science, Computer Science Applications, Politics, Brexit, Policy decision, Political science, 0502 economics and business, 050602 political science & public administration, Research policy, business, 050203 business & management
Abstract: The aim of this study was to examine how institutional barriers arising from policy decisions influence the level of participation of third-party countries in European Framework Programs (EU-FPs). To achieve this, we contrasted the effect of EU funding restrictions following Switzerland’s 2014 reclassification as a “third country” in Horizon 2020, and the political uncertainties resulting from the 2016 Brexit vote in the United Kingdom (UK). We compared the participation patterns of Swiss and UK higher education institutions (HEIs) with control groups of similar European HEIs over time and, complementarily, analyzed changes in the participation of small and medium-sized enterprises (SMEs). Our results showed that the Brexit-induced uncertainty had stronger negative effects than the Swiss reclassification, which was, however, characterized by effective EU funding restrictions. In both cases, the negative impact of institutional barriers was stronger for the more central HEIs in EU-FP networks. These results suggest that the effect of institutional barriers is closely linked to consortium building mechanisms, where research collaboration requires stability and projection over the long term. Regarding individual grants, the impact was stronger for Marie Skłodowska-Curie actions than for European Research Council grants, suggesting that a researcher’s mobility is affected by political uncertainties. Finally, in the UK case, we observed a steep decrease in the participation of SMEs. Based on these results, we suggest that a stable framework of participation and a clear ruling on relationships with the EU for what concerns people’s mobility and economic relationships are key to fostering the participation of third-party countries.
Published: 2020
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37. Cultivating a learning culture in the US Navy

Author: Liz Cavallaro and William J. Nault
Subjects: Learning culture, Organizational Behavior and Human Resource Management, National security, Knowledge management, business.industry, media_common.quotation_subject, 05 social sciences, Learning organization, Competitive advantage, Education, Unit (housing), Navy, Political science, 0502 economics and business, 050211 marketing, Conversation, Bureaucracy, business, 050203 business & management, media_common
Abstract: Purpose This paper aims to explore the cultivation of a learning culture in the US Navy (USN). The intent of preparing and sharing this research is to reveal the particular challenges of developing learning organization capability in national security organizations. This paper believes this effort will contribute to the evolution and establishment of learning organization models that are replicable across and adaptable to distinct industrial settings. Design/methodology/approach Several efforts were explored and assessed by applying relevant research in the learning organization literature to trends in current organizational practice within the USN. Findings Recent USN learning culture efforts align with the broader, multi-sector, global trend toward building learning organizations to develop people as a source of competitive advantage. This research reveals the trials of enabling learning organizations across large, hierarchical bureaucracies with substantial structural and cultural barriers. The myriad obstacles currently being addressed by the USN, both at an institutional level and at smaller organization and unit levels, can inform the development of learning cultures. In particular, this research highlights the need to align specific efforts to the appropriate level of the organization. Originality/value This paper contributes to the learning organization conversation by examining the associated challenges through a multi-level framework – top, middle and bottom.
Published: 2020
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38. A climate change indicator framework for rangelands and pastures of the USA

Author: Julian Reyes, Dennis S. Ojima, John A. Tanaka, Susan M. Casby-Horton, Nancy Cavallaro, Robert A. Washington-Allen, Rebecca Aicher, Derek W. Bailey, and Steven R. Archer
Subjects: Atmospheric Science, Global and Planetary Change, education.field_of_study, 010504 meteorology & atmospheric sciences, Land use, business.industry, 0208 environmental biotechnology, Environmental resource management, Population, 02 engineering and technology, Land cover, 01 natural sciences, 020801 environmental engineering, Ecosystem services, Water conservation, Adaptive management, Geography, Grazing, Rangeland, business, education, 0105 earth and related environmental sciences
Abstract: Rangelands and pastures include grasslands, savannas, shrublands, and woodlands and are often maintained to support grazing animals. Rangelands and pastures cover more than one-third of the land area in the USA and a similar extent globally. The ecosystem goods and services associated with rangeland and pastureland include critical wildlife habitat, forage for livestock, amenities related to water conservation, sustainable soil functions, and soil stabilization and support a diversity of biota and livelihoods. This paper provides a framework for development of a socio-ecological system (SES)–oriented set of indicators for rangeland and pasture systems to support evaluation of impacts of climate and land use changes. These indicators will also serve to inform adaptive management practices. We present a rationale for using an SES approach to evaluate trends and vulnerabilities of rangeland and pasture systems and provide an example of a set of system indicators arising from the SES approach. The indicators include evaporative demand, land cover extent, aboveground plant biomass, human demographics (population age distribution), cattle numbers, and economic value of cattle products relative to total agricultural value. These indicators are not meant to be comprehensive but are offered to illustrate how they might be used in a SES approach to plan for, assess, and mitigate climate change impacts. The conceptual framework provides a systems perspective on the impact of climate change on the socio-ecological dynamics of rangeland and pasture systems including measures of the resilience and vulnerability of ecosystem services with respect to the six indicators. The article focusses on livestock production in rangeland ecosystems, recognizing that additional work is needed to address pastures and other ecosystem services. Examples of the types of regional information associated with the indicators are provided. Guidance for future efforts in indicator development is offered. This framework will serve to guide future development of indicators for rangeland and pasture components of a larger national effort of indicators.
Published: 2020
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39. Convergent pathological and ultrasound features in hereditary syndromic and non‐syndromic minifascicular neuropathy related to <scp> DHH </scp>

Author: Federica Taioli, Tiziana Cavallaro, Fulvia Baldinotti, Federica Boso, Giampietro Zanette, Silvano Bertelloni, Gian Maria Fabrizi, and Salvatore Monaco
Subjects: Proband, Pathology, medicine.medical_specialty, Microscopy, Acoustic, Gonadal dysgenesis, nerve ultrasound, Consanguinity, 03 medical and health sciences, 0302 clinical medicine, Sural Nerve, inherited neuropathy, medicine, Humans, Hedgehog Proteins, Genetic Testing, Disorders of sex development, Pathological, Desert hedgehog, Genetic testing, Disorder of Sex Development, 46,XY, Nerve biopsy, medicine.diagnostic_test, business.industry, Siblings, General Neuroscience, Syndrome, Middle Aged, medicine.disease, gonadal dysgenesia, minifascicular neuropathy, medicine.anatomical_structure, desert Hedgehog, 030220 oncology & carcinogenesis, Female, Neurology (clinical), Hereditary Sensory and Motor Neuropathy, business, Perineurium, 030217 neurology & neurosurgery
Abstract: Minifascicular neuropathy (MN) is a rare, autosomal recessive disease with prominent structural changes of peripheral nerves. So far, it has been observed in females with a 46,XY karyotype and mutations of the Desert Hedgehog (DHH) gene, thus linking MN to gonadal dysgenesis (GD) and disorders of sex development (DSD). However, a 46,XX proband with normal female sex and gender development underwent clinical evaluations, nerve conduction studies and genetic screening for a severe motor-sensory neuropathy with a pathological phenotype that hinted at MN. Indeed, sural nerve biopsy revealed a profound disturbance of perineurium development with a thin and loose structure. High-resolution ultrasound (HRUS) also disclosed diffuse changes of nerve echotexture that visibly correlated with the pathological features. After extensive genetic testing, a novel homozygous DHH null mutation (p.Ser185*) was identified in the proband and in her sister, who was affected by a similar motor-sensory neuropathy, but was eventually found to be a 46,XY patient according to a late diagnosis of DSD with complete GD. DHH should therefore be considered as a possible cause of rare non-syndromic hereditary motor-sensory neuropathies, regardless of DSD. Furthermore, HRUS could effectively smooth the complex diagnostic workup as it demonstrated a high predictive power to detect MN, providing the same detailed correlations to the pathologic features of the nerve biopsy and Dhh-/- mice in both sisters. Hence, HRUS may assume a pivotal role in guiding molecular analysis in individuals with or without DSD.
Published: 2020
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40. CIDP, CMT1B, or CMT1B plus CIDP?

Author: Tiziana Cavallaro, Davide Cardellini, Sergio Ferrari, Federica Taioli, Giampietro Zanette, Laura Bertolasi, and Gian Maria Fabrizi
Subjects: medicine.medical_specialty, Pathology, Neurology, Dermatology, Myelin protein zero (MPZ), 03 medical and health sciences, 0302 clinical medicine, Charcot-Marie-Tooth Disease, Peripheral nerve, Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), medicine, Humans, Peripheral Nerves, 030212 general & internal medicine, Ultrasonography, Subclinical infection, Neuroradiology, business.industry, Myelin protein zero, Polyradiculoneuropathy, General Medicine, medicine.disease, Null allele, Charcot-Marie-Tooth disease (CMT), Psychiatry and Mental health, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Neurology (clinical), Neurosurgery, Nerve high-resolution ultrasound (HRUS), business, Myelin P0 Protein, 030217 neurology & neurosurgery
Abstract: Charcot-Marie-Tooth disease type 1 (CMT1) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have distinct clinical and neurophysiological features that result from dysmyelination in CMT1 and macrophage-mediated segmental demyelination in CIDP. CMT1 may occur in genetically isolated cases with atypical presentations that converge phenotypically with CIDP; in rare cases, however, CMT1 may be complicated by superimposed CIDP. We report the case of a patient harboring a de novo heterozygous null mutation of the myelin protein zero (MPZ) gene and affected by subclinical CMT1B who became symptomatic due to superimposed CIDP. Peripheral nerve high-resolution ultrasound (HRUS) aided in establishing the coexistence of CMT1B and CIDP; the diagnosis was further supported by favorable clinical, neurophysiological, and ultrasound responses to immunoglobulin therapy.
Published: 2020
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41. Strengthening National Immunization Technical Advisory Groups in resource-limited settings: current and potential linkages with polio national certification committees

Author: Abigail Shefer, S. Deblina Datta, Koffi Isidore Kouadio, Blanche-Philomene Melanga Anya, Morgane Donadel, Kathleen F. Cavallaro, Humayun Asghar, Irtaza Chaudhri, and Sharon A Greene
Subjects: Economic growth, medicine.medical_specialty, Certification, Advisory Committees, 030231 tropical medicine, Polio endgame, Health administration, 03 medical and health sciences, 0302 clinical medicine, Poliomyelitis eradication, medicine, Humans, National Immunization Technical Advisory Group (or NITAG), 030212 general & internal medicine, Vaccine decision-making, Polio eradication, Health policy, Response rate (survey), Immunization Programs, Research, Public health, lcsh:Public aspects of medicine, Health services research, lcsh:RA1-1270, medicine.disease, Poliomyelitis, Health workforce capacity-building, Advisory committee, Africa, Immunization, Business, Immunization programme
Abstract: Background Countries are transitioning assets and functions from polio eradication to integrated immunization and surveillance activities. We assessed the extent of linkages between and perceptions of National Immunization Technical Advisory Groups (NITAGs) and National Certification Committees (NCCs) for polio eradication to understand how linkages can be leveraged to improve efficiencies of these expert bodies. Methods During May 2017 to May 2018, we administered a 15-question survey to a NITAG chair or member and an NCC counterpart in all countries of the WHO Regions for Africa (AFR) and for the Eastern Mediterranean (EMR) that had both a NITAG and an NCC. Data were analysed using frequency distributions. Results Of countries with both a NITAG and an NCC (n = 44), the response rate was 92% (22/24) in AFR and 75% (15/20) in EMR. Some respondents reported being very familiar with the functions of the other technical bodies, 36% (8/22) for NITAG members and 38% (14/37) for NCC members. Over 85% (51/59) of respondents felt it was somewhat useful or very useful to strengthen ties between bodies. Nearly all respondents (98%, 58/59) felt that NCC expertise could inform measles and rubella elimination programmes. Conclusions We observed a broad consensus that human resource assets of NCCs may serve an important technical role to support national immunization policy-making. At this stage of the polio eradication initiative, countries should consider how to integrate the technical expertise of NCC members to reinforce NITAGs and maintain the polio essential functions, beginning in countries that have been polio-free for several years.
Published: 2020
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42. Artificial neural networks training acceleration through network science strategies

Author: Antonio Liotta, Pasquale De Meo, Giacomo Fiumara, Ovidiu Bagdasar, and Lucia Cavallaro
Subjects: Artificial neural networks, Artificial neural network, business.industry, Computer science, Deep learning, Network science, Multilayer perceptron, Revise phase, Process (computing), 020206 networking & telecommunications, Computational intelligence, 02 engineering and technology, Theoretical Computer Science, Acceleration, 0202 electrical engineering, electronic engineering, information engineering, 020201 artificial intelligence & image processing, Geometry and Topology, Artificial intelligence, Applications of artificial intelligence, business, Set (psychology), Software
Abstract: The development of deep learning has led to a dramatic increase in the number of applications of artificial intelligence. However, the training of deeper neural networks for stable and accurate models translates into artificial neural networks (ANNs) that become unmanageable as the number of features increases. This work extends our earlier study where we explored the acceleration effects obtained by enforcing, in turn, scale freeness, small worldness, and sparsity during the ANN training process. The efficiency of that approach was confirmed by recent studies (conducted independently) where a million-node ANN was trained on non-specialized laptops. Encouraged by those results, our study is now focused on some tunable parameters, to pursue a further acceleration effect. We show that, although optimal parameter tuning is unfeasible, due to the high non-linearity of ANN problems, we can actually come up with a set of useful guidelines that lead to speed-ups in practical cases. We find that significant reductions in execution time can generally be achieved by setting the revised fraction parameter ($$\zeta $$ ζ ) to relatively low values.
Published: 2020
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43. Nerve ultrasound in hereditary transthyretin amyloidosis: red flags and possible progression biomarkers

Author: Chiara Briani, Luca Gentile, Giulia Bisogni, Alessandro Salvalaggio, Luca Padua, Anna Mazzeo, Francesca Pastorelli, Mario Cacciavillani, Marta Campagnolo, Alessandro Lozza, Roberto Gasparotti, Rosaria Plasmati, Marina Grandis, Chiara Gemelli, Carlo Martinoli, Daniele Coraci, Tiziana Cavallaro, Laura Obici, M Luigetti, Gian Maria Fabrizi, Francesca Castellani, and Mario Ermani
Subjects: Male, medicine.medical_specialty, Delayed Diagnosis, Neurology, Gene mutation, Amyloid Neuropathies, Gastroenterology, Transthyretin amyloidosis, 03 medical and health sciences, 0302 clinical medicine, ATTRv, Amyloidotic polyneuropathy, Carpal tunnel syndrome, Nerve ultrasound, Internal medicine, medicine, Humans, 030212 general & internal medicine, Neuroradiology, Amyloid Neuropathies, Familial, Original Communication, biology, business.industry, Amyloidosis, Amyloid Neuropathies, Familial Italy Male Median Nerve/diagnostic imaging Middle Aged ATTRv Amyloidotic polyneuropathy Carpal tunnel syndrome Nerve ultrasound Transthyretin amyloidosis, Familial Italy Male Median Nerve/diagnostic imaging Middle Aged ATTRv Amyloidotic polyneuropathy Carpal tunnel syndrome Nerve ultrasound Transthyretin amyloidosis, Middle Aged, medicine.disease, Median nerve, Median Nerve, nervous system diseases, Settore MED/26 - NEUROLOGIA, Transthyretin, Italy, biology.protein, Female, Neurology (clinical), Emblems and Insignia, business, Polyneuropathy, Biomarkers, 030217 neurology & neurosurgery
Abstract: Background Diagnostic delay of hereditary transthyretin amyloidosis (ATTRv, v for variant) prevents timely treatment and, therefore, concurs to the mortality of the disease. The aim of the present study was to explore with nerve ultrasound (US) possible red flags for early diagnosis in ATTRv patients with carpal tunnel syndrome (CTS) and/or polyneuropathy and in pre-symptomatic carriers. Methods Patients and pre-symptomatic carriers with a TTR gene mutation were enrolled from seven Italian centers. Severity of CTS was assessed with neurophysiology and clinical evaluation. Median nerve cross-section area (CSA) was measured with US in ATTRv carriers with CTS (TTR-CTS). One thousand one hundred ninety-six idiopathic CTS were used as controls. Nerve US was also performed in several nerve trunks (median, ulnar, radial, brachial plexi, tibial, peroneal, sciatic, sural) in ATTRv patients with polyneuropathy and in pre-symptomatic carriers. Results Sixty-two subjects (34 men, 28 women, mean age 59.8 years ± 12) with TTR gene mutation were recruited. With regard to CTS, while in idiopathic CTS there was a direct correlation between CTS severity and median nerve CSA (r = 0.55, p r = − 0.473). ATTRv patients with polyneuropathy showed larger CSA than pre-symptomatic carriers in several nerve sites, more pronounced at brachial plexi (p Conclusions The present study identifies nerve morphological US patterns that may help in the early diagnosis (morpho-functional dissociation of median nerve in CTS) and monitoring of pre-symptomatic TTR carriers (larger nerve CSA at proximal nerve sites, especially at brachial plexi).
Published: 2020
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44. Morphology of the Atlantic salmon ( Salmo salar) tongue

Author: Maria Levanti, Antonino Germanà, Giuseppe Montalbano, Francesco Abbate, Rosaria Laurà, Mauro Cavallaro, Germana Patrizia Germanà, and Maria Cristina Guerrera
Subjects: Atlantic salmon, Morphology (linguistics), 040301 veterinary sciences, Confocal, Salmo salar, Biology, law.invention, 0403 veterinary science, Rosette (botany), 03 medical and health sciences, Aquaculture, Apex (mollusc), tongue, Tongue, Confocal microscopy, law, morphology, medicine, Animals, Salmo, 0303 health sciences, Microscopy, Confocal, General Veterinary, business.industry, 04 agricultural and veterinary sciences, General Medicine, Anatomy, biology.organism_classification, medicine.anatomical_structure, Microscopy, Fluorescence, 030301 anatomy & morphology, Microscopy, Electron, Scanning, business
Abstract: The Atlantic salmon (Salmo salar) is a freshwater and marine fish of the family Salmonidae, widely farmed in aquaculture facilities in several countries. The salmon are carnivorous, but in aquaculture, alternative foods have been experienced. It is well known that feeding in captivity should cause adaptation and modifications of the morphological characteristics of the oral cavity, especially of tongue; therefore, the aim of this study was to investigate, by light, laser confocal and scanning electron microscopy, the morphological characteristics of the tongue dorsal surface, considering the importance of the correlations between feeding habits and the anatomy of the tongue. Scanning electron microscopy demonstrates the presence of caniniform teeth with oro-aboral orientation surrounded by numerous filiform papillae, single, fused or arranged in row. Oro-aborally, the papillae show an appearance like a rosette and they disappear at level of the root. Light and laser confocal microscopy demonstrates that the mucosa is covered by a non-keratinized stratified pavement epithelium with, in the deepest layer, the presence of a triangular structure whose apex is cranially directed and base facing aborally. In this structure, spindle-shaped cells are present, with a vimentin immunoreactivity, that for their characteristics could be adult mesenchymal stem cells. The obtained data could be useful not only for further studies on the nutrition, but it is interesting the detection of tissues typical of the embryo-fetal phase in the adult specimens tongue, thus giving a basis for studies of potential applications, if any, regarding cell therapies for different clinical indications.
Published: 2020
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45. Can We Predict Surgically Complex Diverticulitis in Elective Cases?

Author: Ronald Bleday, Yuksel Altinel, Paul M Cavallaro, Liliana Bordeianou, Fraz K Ahmed, Rocco Ricciardi, and Marc Rubin
Subjects: Adult, Male, medicine.medical_specialty, Complex disease, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, medicine, Humans, Elective surgery, Colectomy, Diverticulitis, Aged, Retrospective Studies, Gynecology, Acute diverticulitis, business.industry, Patient Selection, Gastroenterology, Outcome measures, General Medicine, Middle Aged, medicine.disease, Acs nsqip, Logistic Models, Elective Surgical Procedures, 030220 oncology & carcinogenesis, Charlson comorbidity index, Female, 030211 gastroenterology & hepatology, Functional status, business
Abstract: BACKGROUND Diverticulitis is separated into complicated and uncomplicated, based on the patient's presentation at the time of his or her initial attack of acute diverticulitis. OBJECTIVE The aim of this study was to identify risk factors for persistent complex diverticulitis, defined as an abscess, fistula, or stricture, at the time of elective surgery, and to characterize outcomes in this patient population. DESIGN This was a retrospective review of 2010 to 2016 in the American College of Surgeons National Surgical Quality Improvement Project database. SETTINGS Individuals diagnosed with diverticulitis who underwent elective surgery were included. PATIENTS A total of 1502 patients underwent elective surgery for diverticulitis, of which 559 (37%) patients had a surgical indication of persistent complex diverticulitis. INTERVENTIONS We performed logistic regression analysis to identify risk factors for complex diverticulitis and evaluated a new prediction model. MAIN OUTCOME MEASURES The predictive factors of persistent complex diverticulitis for elective colon resection were measured. RESULTS The patients with complex diverticulitis were older (p < 0.001), had worse functional status (p < 0.001), more comorbidities (diabetes mellitus and hypertension), and a higher Charlson Comorbidity Index (2.7 vs 1.6, p < 0.001). They were more likely to have a history of tobacco or alcohol use (p < 0.001) and to be malnourished. Interestingly, patients found to have persistent complex diverticulitis did not have more episodes than patients with uncomplicated cases did (p = 0.67). Surgical time was longer in complex diverticulitis, and the patients were more likely to require diverting stomas and concurrent resections of adjacent structures. The area under the curve from the test set was (0.75; 95% CI, 0.72-0.78), sensitivity and specificity were 0.890 (95% CI, 0.870-0.891) and 0.450 (95% CI, 0.410-0.490). LIMITATIONS The study was limited by its retrospective review and observational bias. CONCLUSIONS Patients undergoing elective surgery for complex diverticulitis did not have more episodes. Instead, complex diverticulitis may be a reflection of a complicated patient, suggesting that complicated patients should have a different algorithm of care at the time of their initial presentation with diverticulitis to prevent the development of complex disease. See Video Abstract at http://links.lww.com/DCR/B183. ?PODEMOS PREDECIR DIVERTICULITIS QUIRURGICAMENTE COMPLEJA EN CASOS ELECTIVOS?: La diverticulitis se divide en complicada y sin complicaciones, segun la presentacion del paciente en el momento de su ataque inicial de diverticulitis aguda.El objetivo de este estudio fue identificar los factores de riesgo para la diverticulitis compleja persistente, definida como un absceso, fistula o estenosis, en el momento de la cirugia electiva, y caracterizar los resultados en esta poblacion de pacientes.Esta fue una revision retrospectiva del 2010-2016 en la base de datos del Proyecto de Mejora de la Calidad Quirurgica Nacional del Colegio Estadounidense de Cirujanos.Se incluyeron individuos diagnosticados con diverticulitis que se sometieron a cirugia electiva.1502 pacientes fueron sometidos a cirugia electiva por diverticulitis, de los cuales 559 (37%) pacientes tenian una indicacion quirurgica de diverticulitis compleja persistente.Realizamos un analisis de regresion logistica para identificar los factores de riesgo de diverticulitis compleja y evaluamos un nuevo modelo de prediccion.Se midieron los factores predictivos de diverticulitis compleja persistente para la reseccion de colon electiva.Los pacientes con diverticulitis compleja eran mayores (p
Published: 2020
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46. Young Man With Dyspnea and Hemoptysis

Author: Sarah M. Petteys, Chase Donaldson, Joseph A. Cavallaro, and James B. Haran
Subjects: Male, Hemoptysis, Oxygen inhalation therapy, Inhalation, business.industry, Vaping, Treatment outcome, Oxygen Inhalation Therapy, MEDLINE, Cocaine-Related Disorders, Young Adult, Dyspnea, Treatment Outcome, Cocaine, X ray computed, Anesthesia, Administration, Inhalation, Emergency Medicine, Humans, Medicine, Young adult, Lung Diseases, Interstitial, Tomography, X-Ray Computed, business
Published: 2020
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47. Benchmark for Human-to-Robot Handovers of Unseen Containers With Unknown Filling

Author: Apostolos Modas, Pascal Frossard, Nuno Ferreira Duarte, Konstantinos Chatzilygeroudis, Aude Billard, Andrea Cavallaro, Ricardo Sanchez-Matilla, and Alessio Xompero
Subjects: 0209 industrial biotechnology, Control and Optimization, Computer science, Biomedical Engineering, 02 engineering and technology, Human-Robot Handover, Motion capture, Task (project management), 020901 industrial engineering & automation, Artificial Intelligence, Perception for Manipulation, 0202 electrical engineering, electronic engineering, information engineering, Computer vision, Baseline (configuration management), Performance Evaluation and Benchmarking, business.industry, Mechanical Engineering, Pipeline (software), Computer Science Applications, Human-Computer Interaction, Control and Systems Engineering, Benchmark (computing), RGB color model, Robot, 020201 artificial intelligence & image processing, Computer Vision and Pattern Recognition, Artificial intelligence, business
Abstract: The real-time estimation through vision of the physical properties of objects manipulated by humans is important to inform the control of robots for performing accurate and safe grasps of objects handed over by humans. However, estimating the 3D pose and dimensions of previously unseen objects using only RGB cameras is challenging due to illumination variations, reflective surfaces, transparencies, and occlusions caused both by the human and the robot. In this letter, we present a benchmark for dynamic human-to-robot handovers that do not rely on a motion capture system, markers, or prior knowledge of specific objects. To facilitate comparisons, the benchmark focuses on cups with different levels of transparencies and with an unknown amount of an unknown filling. The performance scores assess the overall system as well as its components in order to help isolate modules of the pipeline that need improvements. In addition to the task description and the performance scores, we also present and distribute as open source a baseline implementation for the overall pipeline to enable comparisons and facilitate progress.
Published: 2020
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48. Voice Differences When Wearing and Not Wearing a Surgical Mask

Author: Vincenzo Di Nicola, Nicola Quaranta, Giada Cavallaro, and Maria Luisa Fiorella
Subjects: medicine.medical_specialty, business.industry, Hearing loss, Statistical difference, Maximum phonation time, Audiology, LPN and LVN, Affect (psychology), Intensity (physics), 030507 speech-language pathology & audiology, 03 medical and health sciences, Speech and Hearing, Surgical mask, Nonverbal communication, 0302 clinical medicine, Otorhinolaryngology, Vocal effort, otorhinolaryngologic diseases, Medicine, medicine.symptom, 030223 otorhinolaryngology, 0305 other medical science, business
Abstract: Summary Objective The purpose of our study was to investigate the impact of surgical mask on some vocal parameters such as F0, vocal intensity, jitter, shimmer and harmonics-to-noise ratio in order to understand how surgical mask can affect voice and verbal communication in adults. Methods The study was carried out on a selected group of 60 healthy subjects. All subjects were trained to voice a vocal sample of a sustained /a/, at a conversational voice intensity for the Maximum Phonation Time (MPT), wearing the surgical mask and then without wearing the surgical mask. Voice samples were recorded directly in Praat. Results There were no statistically significant differences in any acoustic parameter between the masked and unmasked condition. There was a non-significant decrease in vocal intensity in 65% of the subjects while wearing a surgical mask. Conclusions The statistical comparison carried out between all the acoustic voice parameters observed, extracted wearing and not wearing a surgical mask did not reveal any significant statistical difference. Most of the subjects, after wearing the surgical mask, presented a decrease in vocal intensity measured. Our conclusion was that wearing a mask is likely to induce the unconscious need to increase the vocal effort, resulting over time in a greater risk of developing functional dysphonia. The reduction of intensity can affect also social interaction and speech audibility, especially for individuals with hearing loss.
Published: 2023
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49. NeoAPACHE II. Relationship Between Radiographic Pulmonary Area and Pulmonary Hypertension, Mortality, and Hernia Recurrence in Newborns With CDH

Author: Ilaria Amodeo, Nicola Pesenti, Genny Raffaeli, Francesco Macchini, Valentina Condò, Irene Borzani, Nicola Persico, Isabella Fabietti, Giulia Bischetti, Anna Maria Colli, Stefano Ghirardello, Silvana Gangi, Mariarosa Colnaghi, Fabio Mosca, Giacomo Cavallaro, Amodeo, I, Pesenti, N, Raffaeli, G, Macchini, F, Condo, V, Borzani, I, Persico, N, Fabietti, I, Bischetti, G, Colli, A, Ghirardello, S, Gangi, S, Colnaghi, M, Mosca, F, and Cavallaro, G
Subjects: medicine.medical_specialty, Pediatrics, RJ1-570, congenital diaphragmatic hernia, Perimeter, 03 medical and health sciences, Pulmonary hypoplasia, recurrence of the hernia, 0302 clinical medicine, 030225 pediatrics, Internal medicine, medicine.artery, pulmonary hypertension, medicine, 030212 general & internal medicine, Original Research, Lung, business.industry, Congenital diaphragmatic hernia, radiographic lung area, medicine.disease, Pulmonary hypertension, mortality, Clinical trial, stomatognathic diseases, FETO, medicine.anatomical_structure, lung hypoplasia, Pediatrics, Perinatology and Child Health, Pulmonary artery, Cardiology, business, Rare disease
Abstract: Congenital diaphragmatic hernia is a rare disease with high mortality and morbidity due to pulmonary hypoplasia and pulmonary hypertension. The aim of the study is to investigate the relationship between radiographic lung area and systolic pulmonary artery pressure (sPAP) on the first day of life, mortality, and hernia recurrence during the first year of life in infants with a congenital diaphragmatic hernia (CDH). A retrospective data collection was performed on 77 CDH newborns. Echocardiographic sPAP value, deaths, and recurrence cases were recorded. Lung area was calculated by tracing the lung's perimeter, excluding mediastinal structures, and herniated organs, on the preoperative chest X-ray performed within 24 h after birth. Logistic and linear regression analyses were performed. Deceased infants showed lower areas and higher sPAP values. One square centimeter of rising in the total, ipsilateral, and contralateral area was associated with a 22, 43, and 24% reduction in mortality risk. sPAP values showed a decreasing trend after birth, with a maximum of 1.84 mmHg reduction per unitary increment in the ipsilateral area at birth. Recurrence patients showed lower areas, with recurrence risk decreasing by 14 and 29% per unit increment of the total and ipsilateral area. In CDH patients, low lung area at birth reflects impaired lung development and defect size, being associated with increased sPAP values, mortality, and recurrence risk.Clinical Trial Registration: The manuscript is an exploratory secondary analysis of the trial registered at ClinicalTrials.gov with identifier NCT04396028.
Published: 2021

50. Functional benefits of co-occurring autistic symptoms in schizophrenia is delimited by symptom severity

Author: Giulia Agostoni, Margherita Bechi, Marta Bosia, Marco Spangaro, Ahmad Abu-Akel, Roberto Cavallaro, Federica Cocchi, Bechi, M., Abu-Akel, A., Agostoni, G., Bosia, M., Cocchi, F., Spangaro, M., and Cavallaro, R.
Subjects: Psychosis, Autism Spectrum Disorder, Autistic symptoms, Diametric model, Disease cluster, 03 medical and health sciences, 0302 clinical medicine, mental disorders, Medicine, Humans, Functioning, Autistic Disorder, Adverse effect, Biological Psychiatry, Psychopathology, business.industry, medicine.disease, Psychiatry and Mental health, 030227 psychiatry, Psychotic Disorders, Schizophrenia, Autism spectrum disorder, Autism, Biological psychiatry, business, Positive symptoms, 030217 neurology & neurosurgery, Clinical psychology
Abstract: Background Impairments in daily functioning characterize both autism spectrum disorder and schizophrenia. Research has shown that a subsample of schizophrenia patients presents autistic symptoms, leading to the hypothesis that their co-occurrence would be associated with a ‘double dose’ of deficit. A growing body of research examined this hypothesis by looking at the joint effect of autistic and positive psychotic symptoms, and yielded contrasting results, ranging from benefits to adverse effects. We hypothesized that the interactive effect of autistic and positive symptoms on functioning in schizophrenia might depend on the patients' symptom severity. Method In 170 schizophrenia patients, a two-step cluster analysis identified two groups of patients with different levels of autistic and positive symptom severity. Using general linear models, we examined the interactions of groups, autistic and positive symptoms on functioning. Results Autistic and positive symptoms were interactively associated with better functioning, but only in the symptomatically less severe patients. In contrast, autistic and positive symptoms were independently associated with worse functioning in the symptomatically more severe patients. These associations were observed above and beyond the effects of I.Q. and illness duration. Conclusions The findings highlight the complex role played by co-occurring autistic symptoms in schizophrenia, whose beneficial effects on functioning appear to depend on patients’ psychopathological severity. Our findings may help to reconcile the seemingly contrasting results from previous studies, and to understand the heterogeneity of behavior and functional outcomes in schizophrenia. This study underscores the potential utility of routinely assessing autism in schizophrenia, in order to better formulate individualized rehabilitative programs.
Published: 2021

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